Jaundice, Obstructive Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D041781
Similar Terms
Downloads & Tools

Genes

286 genes/proteins associated with the disease Jaundice, Obstructive from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 2.88009
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.17059
TNF tumor necrosis factor 2.12854
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.99437
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.98025
IL6 interleukin 6 1.96086
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.92234
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.92058
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.86823
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.82708
MPO myeloperoxidase 1.80642
PRL prolactin 1.80303
IFNG interferon, gamma 1.7874
IL1B interleukin 1, beta 1.78149
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.77492
CAT catalase 1.75003
BAX BCL2-associated X protein 1.73878
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.70491
TP53 tumor protein p53 1.69017
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.6819
BCL2 B-cell CLL/lymphoma 2 1.61413
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.60617
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.60594
NOS2 nitric oxide synthase 2, inducible 1.6043
TAGLN transgelin 1.59172
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.58255
IGF1 insulin-like growth factor 1 (somatomedin C) 1.56947
IL10 interleukin 10 1.56288
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.55971
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.55673
INHBE inhibin, beta E 1.54815
HMOX1 heme oxygenase 1 1.54766
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.5103
EGR1 early growth response 1 1.50524
NUPR1 nuclear protein, transcriptional regulator, 1 1.50298
TGFB1 transforming growth factor, beta 1 1.49915
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.49226
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.48864
FMO1 flavin containing monooxygenase 1 1.48633
GSTP1 glutathione S-transferase pi 1 1.47762
FOS FBJ murine osteosarcoma viral oncogene homolog 1.47167
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.46568
GADD45A growth arrest and DNA-damage-inducible, alpha 1.46488
VEGFA vascular endothelial growth factor A 1.46356
CCL2 chemokine (C-C motif) ligand 2 1.46304
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.45777
HPN hepsin 1.45326
VCAM1 vascular cell adhesion molecule 1 1.44273
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.44166
GSTT1 glutathione S-transferase theta 1 1.42696
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.42101
PPARG peroxisome proliferator-activated receptor gamma 1.42074
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.41829
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.41613
C10ORF10 chromosome 10 open reading frame 10 1.4065
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.40457
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.4026
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.39785
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.39114
DDIT3 DNA-damage-inducible transcript 3 1.37958
ICAM1 intercellular adhesion molecule 1 1.37846
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.37761
BIRC5 baculoviral IAP repeat containing 5 1.3759
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.37446
CCND1 cyclin D1 1.37132
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.36476
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.36104
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.3556
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.35242
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.34314
ALB albumin 1.34256
GLS2 glutaminase 2 (liver, mitochondrial) 1.34024
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.33464
ARG1 arginase 1 1.32876
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.31837
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.31596
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.30941
PLG plasminogen 1.30941
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.30788
IL1A interleukin 1, alpha 1.30758
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.30604
FABP1 fatty acid binding protein 1, liver 1.30604
HSPA8 heat shock 70kDa protein 8 1.30543
CDKN2A cyclin-dependent kinase inhibitor 2A 1.30543
GRB14 growth factor receptor-bound protein 14 1.30269
EDN1 endothelin 1 1.29719
JUN jun proto-oncogene 1.28703
DCAF8 DDB1 and CUL4 associated factor 8 1.28425
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.28395
NPHP4 nephronophthisis 4 1.28395
SPP1 secreted phosphoprotein 1 1.27875
SOD2 superoxide dismutase 2, mitochondrial 1.27533
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.26917
F3 coagulation factor III (thromboplastin, tissue factor) 1.26917
DUSP1 dual specificity phosphatase 1 1.26638
KLF4 Kruppel-like factor 4 (gut) 1.26298
IGFBP1 insulin-like growth factor binding protein 1 1.26205
MMP2 matrix metallopeptidase 2 1.26175
MAPK3 mitogen-activated protein kinase 3 1.2596
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.25307
POR P450 (cytochrome) oxidoreductase 1.25028
MAPK1 mitogen-activated protein kinase 1 1.24812
KCNK15 potassium channel, two pore domain subfamily K, member 15 1.24465
NAP1L1 nucleosome assembly protein 1-like 1 1.24307
MBP myelin basic protein 1.23868
NQO1 NAD(P)H dehydrogenase, quinone 1 1.23775
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.22339
REN renin 1.22112
PCNA proliferating cell nuclear antigen 1.21855
LOX lysyl oxidase 1.21823
ATF3 activating transcription factor 3 1.21599
RPSA ribosomal protein SA 1.20913
FAS Fas cell surface death receptor 1.20687
LDLR low density lipoprotein receptor 1.20526
CXCL8 chemokine (C-X-C motif) ligand 8 1.19835
INS insulin 1.19672
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.19477
STMN1 stathmin 1 1.19445
TIMP3 TIMP metallopeptidase inhibitor 3 1.19445
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.19345
ANXA2 annexin A2 1.18816
ANXA4 annexin A4 1.18718
KRT18 keratin 18, type I 1.1862
SMAD7 SMAD family member 7 1.18424
RNF152 ring finger protein 152 1.18126
EIF4B eukaryotic translation initiation factor 4B 1.18026
NPPB natriuretic peptide B 1.17827
RXRG retinoid X receptor, gamma 1.17827
PLAT plasminogen activator, tissue 1.17794
H2AFX H2A histone family, member X 1.17794
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.17268
GDF11 growth differentiation factor 11 1.17202
CXCL2 chemokine (C-X-C motif) ligand 2 1.17067
NFE2L2 nuclear factor, erythroid 2-like 2 1.17067
CLU clusterin 1.16799
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.16368
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.16203
CRIP1 cysteine-rich protein 1 (intestinal) 1.16137
COL3A1 collagen, type III, alpha 1 1.1607
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.15729
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.15593
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.15593
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.15256
DPP4 dipeptidyl-peptidase 4 1.15055
RET ret proto-oncogene 1.14781
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 1.14678
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.14507
ISYNA1 inositol-3-phosphate synthase 1 1.13997
FASN fatty acid synthase 1.13929
E2F1 E2F transcription factor 1 1.13862
UNG uracil-DNA glycosylase 1.13724
GSTA1 glutathione S-transferase alpha 1 1.13655
PHYH phytanoyl-CoA 2-hydroxylase 1.13586
TTC23 tetratricopeptide repeat domain 23 1.13177
BICD2 bicaudal D homolog 2 (Drosophila) 1.13143
TTL tubulin tyrosine ligase 1.13143
COL1A1 collagen, type I, alpha 1 1.13143
EPAS1 endothelial PAS domain protein 1 1.12973
S100A6 S100 calcium binding protein A6 1.12973
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.12973
HNF4A hepatocyte nuclear factor 4, alpha 1.12737
CREM cAMP responsive element modulator 1.12495
BHLHE40 basic helix-loop-helix family, member e40 1.12461
RB1 retinoblastoma 1 1.12461
PHF1 PHD finger protein 1 1.12426
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 1.12426
PA2G4 proliferation-associated 2G4, 38kDa 1.12391
PPL periplakin 1.12391
APOA4 apolipoprotein A-IV 1.12219
AKR1C3 aldo-keto reductase family 1, member C3 1.11639
FGA fibrinogen alpha chain 1.11255
FUNDC2 FUN14 domain containing 2 1.11046
MAP1A microtubule-associated protein 1A 1.11046
FDPS farnesyl diphosphate synthase 1.11011
AKR1C1 aldo-keto reductase family 1, member C1 1.10942
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.10872
THRA thyroid hormone receptor, alpha 1.10803
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.10527
GFAP glial fibrillary acidic protein 1.1014
HMGB1 high mobility group box 1 1.09857
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.09822
HSPB3 heat shock 27kDa protein 3 1.09681
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30 1.09541
FAM69C family with sequence similarity 69, member C 1.09506
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.09436
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 1.09436
FKBP5 FK506 binding protein 5 1.09401
DNASE1 deoxyribonuclease I 1.09119
COL11A1 collagen, type XI, alpha 1 1.08726
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.08726
FNDC4 fibronectin type III domain containing 4 1.08549
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.08549
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.08478
RGS8 regulator of G-protein signaling 8 1.08442
ERP29 endoplasmic reticulum protein 29 1.08407
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.08372
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.08301
THRB thyroid hormone receptor, beta 1.08301
S100A9 S100 calcium binding protein A9 1.07875
PARP1 poly (ADP-ribose) polymerase 1 1.07804
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.07696
CES2 carboxylesterase 2 1.07447
ADIPOR2 adiponectin receptor 2 1.07376
BCL6B B-cell CLL/lymphoma 6, member B 1.07234
LGALS3 lectin, galactoside-binding, soluble, 3 1.07234
ECI1 enoyl-CoA delta isomerase 1 1.07057
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.06734
CRP C-reactive protein, pentraxin-related 1.06734
FSHB follicle stimulating hormone, beta polypeptide 1.06734
GRB7 growth factor receptor-bound protein 7 1.06661
PPARA peroxisome proliferator-activated receptor alpha 1.06442
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.06406
MRPS18B mitochondrial ribosomal protein S18B 1.06152
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.06152
TBX3 T-box 3 1.0608
CTGF connective tissue growth factor 1.06008
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.05793
ACTA1 actin, alpha 1, skeletal muscle 1.05793
S100A8 S100 calcium binding protein A8 1.05757
SEC31A SEC31 homolog A (S. cerevisiae) 1.05573
ANK1 ankyrin 1, erythrocytic 1.05535
ACBD7 acyl-CoA binding domain containing 7 1.05498
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.05498
CD96 CD96 molecule 1.05498
MMP9 matrix metallopeptidase 9 1.05015
CPN1 carboxypeptidase N, polypeptide 1 1.05015
SELM selenoprotein M 1.04978
IL4 interleukin 4 1.04868
CTSK cathepsin K 1.04831
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.04757
LAMB2 laminin, beta 2 (laminin S) 1.04574
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 1.04501
LRRC8E leucine rich repeat containing 8 family, member E 1.04352
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 1.04352
NPTXR neuronal pentraxin receptor 1.04352
VIM vimentin 1.04276
HDC histidine decarboxylase 1.04239
CCNG1 cyclin G1 1.04163
HINT1 histidine triad nucleotide binding protein 1 1.04014
PRDX1 peroxiredoxin 1 1.03976
FASLG Fas ligand (TNF superfamily, member 6) 1.03976
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1.03939
AACS acetoacetyl-CoA synthetase 1.03939
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.03604
CRH corticotropin releasing hormone 1.03567
GCKR glucokinase (hexokinase 4) regulator 1.03493
RAB30 RAB30, member RAS oncogene family 1.03456
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.03456
MAG myelin associated glycoprotein 1.03419
MYL10 myosin, light chain 10, regulatory 1.03197
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.03159
CYP3A cytochrome P450, family 3, subfamily A 1.03084
NGFR nerve growth factor receptor 1.03046
ARC activity-regulated cytoskeleton-associated protein 1.03046
FADS1 fatty acid desaturase 1 1.03046
CCND3 cyclin D3 1.03009
FOXP3 forkhead box P3 1.03009
ANXA1 annexin A1 1.03009
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.02971
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.02971
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.02933
CHGA chromogranin A 1.02933
KLF5 Kruppel-like factor 5 (intestinal) 1.02783
UGDH UDP-glucose 6-dehydrogenase 1.02522
OAF OAF homolog (Drosophila) 1.02485
EIF4E eukaryotic translation initiation factor 4E 1.02485
C1S complement component 1, s subcomponent 1.02485
FFAR3 free fatty acid receptor 3 1.02336
INSIG1 insulin induced gene 1 1.02262
HAL histidine ammonia-lyase 1.02188
NPVF neuropeptide VF precursor 1.02114
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.02003
CDC25A cell division cycle 25A 1.01928
GPNMB glycoprotein (transmembrane) nmb 1.01928
FOSL2 FOS-like antigen 2 1.01928
TGFBI transforming growth factor, beta-induced, 68kDa 1.01663
CDK4 cyclin-dependent kinase 4 1.01549
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1.01474
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.01474
GFRA2 GDNF family receptor alpha 2 1.01474
GATA3 GATA binding protein 3 1.01399
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.01361
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 1.01174
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 1.01137
WWC3 WWC family member 3 1.01137
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.01025