Jaundice Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Yellow pigmentation of the skin or sclera due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream. (Human Phenotype Ontology, HP_0000952)
External Link https://www.disgenet.org/browser/0/1/0/C0022350
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Genes

76 genes associated with the disease Jaundice in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE2 angiotensin I converting enzyme 2
ACR acrosin
ACTB actin, beta
ADM adrenomedullin
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ANK1 ankyrin 1, erythrocytic
BRD1 bromodomain containing 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CFH complement factor H
COL4A1 collagen, type IV, alpha 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAO D-amino-acid oxidase
DPP4 dipeptidyl-peptidase 4
G6PD glucose-6-phosphate dehydrogenase
GGTLC1 gamma-glutamyltransferase light chain 1
GH1 growth hormone 1
GPBAR1 G protein-coupled bile acid receptor 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAP2 GRB2-related adaptor protein 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
IL6 interleukin 6
KLHL1 kelch-like family member 1
LBP lipopolysaccharide binding protein
LOC101060233 medium-wave-sensitive opsin 1
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like
LYZ lysozyme
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MARCKSL1 MARCKS-like 1
MUC2 mucin 2, oligomeric mucus/gel-forming
NPHP3 nephronophthisis 3 (adolescent)
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2
PCNA proliferating cell nuclear antigen
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PNPLA6 patatin-like phospholipase domain containing 6
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POMC proopiomelanocortin
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRLR prolactin receptor
RDX radixin
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
S100A12 S100 calcium binding protein A12
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SYCE1L synaptonemal complex central element protein 1-like
SYK spleen tyrosine kinase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCAM1 vascular cell adhesion molecule 1
WLS wntless Wnt ligand secretion mediator