K562_Alendronate sodium trihydrate_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Alendronate sodium trihydrate 10µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
Similar Terms
Downloads & Tools

Genes

1000 genes differentially expressed following the K562_Alendronate sodium trihydrate_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
BCAS3 breast carcinoma amplified sequence 3 0.0832545
SND1 staphylococcal nuclease and tudor domain containing 1 0.0749375
ACTN4 actinin, alpha 4 0.0725239
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0698609
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0670992
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0657777
RPS2 ribosomal protein S2 0.0613659
COPA coatomer protein complex, subunit alpha 0.0543181
MAPK14 mitogen-activated protein kinase 14 0.0535828
SETD5 SET domain containing 5 0.05269
NMU neuromedin U 0.0523713
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0523507
TRIP12 thyroid hormone receptor interactor 12 0.0513654
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0506569
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0504685
SET SET nuclear proto-oncogene 0.0499129
PHF14 PHD finger protein 14 0.0484595
MARCHF3 membrane associated ring-CH-type finger 3 0.0477098
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0469858
ZFR zinc finger RNA binding protein 0.0463362
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0461985
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0452205
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0452188
ZCCHC7 zinc finger, CCHC domain containing 7 0.0445586
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.044301
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0441411
MAN1A1 mannosidase, alpha, class 1A, member 1 0.043437
CELF1 CUGBP, Elav-like family member 1 0.0432534
CNKSR3 CNKSR family member 3 0.0423897
HDLBP high density lipoprotein binding protein 0.0423776
MBNL2 muscleblind-like splicing regulator 2 0.041471
CPED1 cadherin-like and PC-esterase domain containing 1 0.0411952
MRPS25 mitochondrial ribosomal protein S25 0.0406932
SON SON DNA binding protein 0.0405553
FAM222B family with sequence similarity 222, member B 0.0403801
CDK13 cyclin-dependent kinase 13 0.040336
CMC4 C-x(9)-C motif containing 4 0.0391728
NCAM2 neural cell adhesion molecule 2 0.0389717
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.0388032
STAT5B signal transducer and activator of transcription 5B 0.0386141
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.0384553
LMAN1 lectin, mannose-binding, 1 0.0382887
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.0382596
SERBP1 SERPINE1 mRNA binding protein 1 0.0380724
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.0380263
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.037906
GLG1 golgi glycoprotein 1 0.0378219
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.0377862
THSD4 thrombospondin, type I, domain containing 4 0.0375189
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0373936
CTCF CCCTC-binding factor (zinc finger protein) 0.0370836
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0369969
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0366489
ADD1 adducin 1 (alpha) 0.0364746
ACTG1 actin gamma 1 0.0363551
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0357304
CDK6 cyclin-dependent kinase 6 0.035354
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0353299
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.0350441
FANCI Fanconi anemia, complementation group I 0.0350174
BCAP29 B-cell receptor-associated protein 29 0.0347695
CALR calreticulin 0.0346418
KHSRP KH-type splicing regulatory protein 0.0346013
APTX aprataxin 0.0342739
PRR11 proline rich 11 0.0341975
TBCK TBC1 domain containing kinase 0.0341829
SEC24D SEC24 family member D 0.0341696
TAOK3 TAO kinase 3 0.0339089
RTN4 reticulon 4 0.0335596
MUSK muscle, skeletal, receptor tyrosine kinase 0.0334797
ANO6 anoctamin 6 0.0334401
ELP6 elongator acetyltransferase complex subunit 6 0.0332781
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0332773
FBXO42 F-box protein 42 0.0332478
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0332341
RICTOR RPTOR independent companion of MTOR, complex 2 0.0330677
RPS11 ribosomal protein S11 0.0328694
LATS1 large tumor suppressor kinase 1 0.0325567
MTDH metadherin 0.0325125
ZNF846 zinc finger protein 846 0.0324763
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.0324156
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0322777
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0321382
KIF2A kinesin heavy chain member 2A 0.0321139
PTGES2 prostaglandin E synthase 2 0.0320577
BRWD1 bromodomain and WD repeat domain containing 1 0.0319748
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.0319387
GAB2 GRB2-associated binding protein 2 0.0319015
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0317644
ATM ATM serine/threonine kinase 0.0317603
SCLT1 sodium channel and clathrin linker 1 0.0316437
RPL4 ribosomal protein L4 0.0316091
WASF2 WAS protein family, member 2 0.031571
SULF2 sulfatase 2 0.0309317
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0308382
TTL tubulin tyrosine ligase 0.03057
SQSTM1 sequestosome 1 0.0304945
NCALD neurocalcin delta 0.03045
ATP9B ATPase, class II, type 9B 0.0303632
UBA2 ubiquitin-like modifier activating enzyme 2 0.0303497
SRRM2 serine/arginine repetitive matrix 2 0.0303067
NUCB1 nucleobindin 1 0.0302698
FCHSD2 FCH and double SH3 domains 2 0.0301872
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.0300754
GSPT1 G1 to S phase transition 1 0.0300572
DLG5 discs, large homolog 5 (Drosophila) 0.0300366
AARS1 alanyl-tRNA synthetase 1 0.0299679
NBAS neuroblastoma amplified sequence 0.0299599
EIF3J eukaryotic translation initiation factor 3, subunit J 0.0298877
ELP4 elongator acetyltransferase complex subunit 4 0.0298241
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.029802
CLYBL citrate lyase beta like 0.0297844
KMT2C lysine (K)-specific methyltransferase 2C 0.0297386
NCOA3 nuclear receptor coactivator 3 0.0297325
MED15 mediator complex subunit 15 0.0297323
ANKRD11 ankyrin repeat domain 11 0.0295828
KRT8 keratin 8, type II 0.0295075
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0294039
RCL1 RNA terminal phosphate cyclase-like 1 0.0293323
ZNF106 zinc finger protein 106 0.0292336
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.0290698
SEC31A SEC31 homolog A (S. cerevisiae) 0.0290672
EXOC4 exocyst complex component 4 0.0289992
RLF rearranged L-myc fusion 0.028819
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0288124
CMIP c-Maf inducing protein 0.028772
CLTC clathrin, heavy chain (Hc) 0.0287339
DCAKD dephospho-CoA kinase domain containing 0.028657
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.028379
RPL13A ribosomal protein L13a 0.0283673
PDIA4 protein disulfide isomerase family A, member 4 0.0282096
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0281559
MYH9 myosin, heavy chain 9, non-muscle 0.0280028
SLC30A9 solute carrier family 30 (zinc transporter), member 9 0.0278726
RPS5 ribosomal protein S5 0.0278315
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0278314
DCAF7 DDB1 and CUL4 associated factor 7 0.0277369
SESN2 sestrin 2 0.0277359
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0276225
PITRM1 pitrilysin metallopeptidase 1 0.0275481
UBN2 ubinuclein 2 0.0274472
NCAPG2 non-SMC condensin II complex, subunit G2 0.0273753
NUP214 nucleoporin 214kDa 0.0273698
IGF1R insulin-like growth factor 1 receptor 0.0273564
FUBP1 far upstream element (FUSE) binding protein 1 0.0272548
STIM1 stromal interaction molecule 1 0.0272464
PRDX5 peroxiredoxin 5 0.027066
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0267385
FTL ferritin, light polypeptide 0.0267148
MBD5 methyl-CpG binding domain protein 5 0.0266652
UBAP1 ubiquitin associated protein 1 0.0265886
NUP88 nucleoporin 88kDa 0.0265661
STRBP spermatid perinuclear RNA binding protein 0.026548
RBM39 RNA binding motif protein 39 0.0264732
SCAF11 SR-related CTD-associated factor 11 0.0263959
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0263434
TTC17 tetratricopeptide repeat domain 17 0.0262327
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0261688
GTPBP4 GTP binding protein 4 0.0261419
USP15 ubiquitin specific peptidase 15 0.0259635
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0259199
DNPEP aspartyl aminopeptidase 0.0259009
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0258375
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 0.0258261
TLN1 talin 1 0.0256461
NUP155 nucleoporin 155kDa 0.0256053
RSRC1 arginine/serine-rich coiled-coil 1 0.02559
THOC2 THO complex 2 0.0255759
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0255569
AK1 adenylate kinase 1 0.0253385
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0253278
CLCN3 chloride channel, voltage-sensitive 3 0.0252607
NSUN6 NOP2/Sun domain family, member 6 0.0252596
PPP4R3A protein phosphatase 4 regulatory subunit 3A 0.0252267
DCTN2 dynactin 2 (p50) 0.0249619
CASC3 cancer susceptibility candidate 3 0.0249445
TSPAN14 tetraspanin 14 0.0249049
GALK2 galactokinase 2 0.024884
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.02485
SELENOF selenoprotein F 0.024799
OLA1 Obg-like ATPase 1 0.0247719
BMP2K BMP2 inducible kinase 0.0247153
RAD51B RAD51 paralog B 0.0246991
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0246413
PDIA5 protein disulfide isomerase family A, member 5 0.0245827
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0245423
H4C8 H4 clustered histone 8 0.024488
CC2D1A coiled-coil and C2 domain containing 1A 0.0244472
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0243576
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.024352
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0242426
LMNA lamin A/C 0.0242231
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0241827
SAE1 SUMO1 activating enzyme subunit 1 0.0241215
AGO2 argonaute RISC catalytic component 2 0.0241048
DMXL1 Dmx-like 1 0.024065
SIL1 SIL1 nucleotide exchange factor 0.0240187
SHCBP1 SHC SH2-domain binding protein 1 0.0239703
CNST consortin, connexin sorting protein 0.0239703
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0239393
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.0239325
TMEM267 transmembrane protein 267 0.0239073
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 0.0238796
DBF4B DBF4 zinc finger B 0.0238728
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 0.0238636
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0238389
CCDC91 coiled-coil domain containing 91 0.0237524
H2AC6 H2A clustered histone 6 0.0237261
ANKRD28 ankyrin repeat domain 28 0.0236512
POM121 POM121 transmembrane nucleoporin 0.0236318
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0236145
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.0236022
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.023541
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0234457
HM13 histocompatibility (minor) 13 0.0233322
RPS17 ribosomal protein S17 0.0232964
DENND1A DENN/MADD domain containing 1A 0.0232759
TRIM37 tripartite motif containing 37 0.0232696
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.023267
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0232614
HCFC1 host cell factor C1 0.0231816
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0231496
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0231473
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.023021
CD47 CD47 molecule 0.0229281
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0228656
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.0228442
FBXO11 F-box protein 11 0.0228424
CEP85L centrosomal protein 85kDa-like 0.0227778
CDC42SE2 CDC42 small effector 2 0.0227479
ZNF124 zinc finger protein 124 0.022739
EYA3 EYA transcriptional coactivator and phosphatase 3 0.0227238
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0226978
TNIK TRAF2 and NCK interacting kinase 0.0226682
RAB6A RAB6A, member RAS oncogene family 0.0226463
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0226323
PRRC2C proline-rich coiled-coil 2C 0.0226236
OXCT1 3-oxoacid CoA transferase 1 0.0226023
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.022571
CCNY cyclin Y 0.0225409
MYH10 myosin, heavy chain 10, non-muscle 0.0225366
PBRM1 polybromo 1 0.0225296
KIF5B kinesin family member 5B 0.0225027
LONP1 lon peptidase 1, mitochondrial 0.0224876
CALU calumenin 0.0224452
RPL27 ribosomal protein L27 0.0223447
CSDE1 cold shock domain containing E1, RNA-binding 0.0223243
MDN1 MDN1, midasin homolog (yeast) 0.0221943
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0221357
ZFHX3 zinc finger homeobox 3 0.0219821
TMEM263 transmembrane protein 263 0.021903
EVI5 ecotropic viral integration site 5 0.0218909
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.0218433
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0218396
RRBP1 ribosome binding protein 1 0.0217469
FAF2 Fas associated factor family member 2 0.0217035
WASHC5 WASH complex subunit 5 0.0216918
AIG1 androgen-induced 1 0.0216789
POLK polymerase (DNA directed) kappa 0.0216445
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0216415
MIMS1 mitochondrial inner membrane scaffold 1 0.0216404
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0214991
SMAD3 SMAD family member 3 0.021497
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.0214799
KLHDC10 kelch domain containing 10 0.0214793
ANK1 ankyrin 1, erythrocytic 0.0214544
ATG4B autophagy related 4B, cysteine peptidase 0.0213865
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.0213776
ATAD2 ATPase family, AAA domain containing 2 0.0213564
NMT1 N-myristoyltransferase 1 0.0212802
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0211905
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0211526
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0211296
ZGRF1 zinc finger, GRF-type containing 1 0.0210683
PICALM phosphatidylinositol binding clathrin assembly protein 0.0210434
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0209972
CRY1 cryptochrome circadian clock 1 0.0208553
CD63 CD63 molecule 0.0208476
SRPK1 SRSF protein kinase 1 0.0208308
PRMT5 protein arginine methyltransferase 5 0.0207545
CENPP centromere protein P 0.0207334
YEATS2 YEATS domain containing 2 0.0207071
SMC1A structural maintenance of chromosomes 1A 0.0206573
TTC19 tetratricopeptide repeat domain 19 0.0206388
PNISR PNN-interacting serine/arginine-rich protein 0.0206161
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0205782
CEP95 centrosomal protein 95kDa 0.0205593
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.0204933
ZCCHC10 zinc finger, CCHC domain containing 10 0.0204882
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.02047
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.0204606
NLK nemo-like kinase 0.0204172
CEP192 centrosomal protein 192kDa 0.0204056
LAMP2 lysosomal-associated membrane protein 2 0.0203518
RPS16 ribosomal protein S16 0.0203148
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 0.0202886
USP36 ubiquitin specific peptidase 36 0.0202187
TUBB tubulin, beta class I 0.0201929
CD46 CD46 molecule, complement regulatory protein 0.0201846
TM9SF2 transmembrane 9 superfamily member 2 0.0201666
WDR36 WD repeat domain 36 0.0201443
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0201286
GNAS GNAS complex locus 0.0201067
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0200907
RPS23 ribosomal protein S23 0.0200113
DPP9 dipeptidyl-peptidase 9 0.0200056
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.0199967
MPC2 mitochondrial pyruvate carrier 2 0.0199942
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.019944
HDAC2 histone deacetylase 2 0.0199389
NUP62 nucleoporin 62kDa 0.019906
USP32 ubiquitin specific peptidase 32 0.0199049
SIK3 SIK family kinase 3 0.0198953
LYRM4 LYR motif containing 4 0.019895
GFRA1 GDNF family receptor alpha 1 0.0198775
ANAPC5 anaphase promoting complex subunit 5 0.0198663
ZC3H8 zinc finger CCCH-type containing 8 0.0198297
RYBP RING1 and YY1 binding protein 0.0197263
LETMD1 LETM1 domain containing 1 0.0197263
C2CD3 C2 calcium-dependent domain containing 3 0.0196989
USP20 ubiquitin specific peptidase 20 0.0196964
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0196754
TMEM117 transmembrane protein 117 0.0196339
SPC25 SPC25, NDC80 kinetochore complex component 0.0196223
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0196109
RNF111 ring finger protein 111 0.0195265
PKM pyruvate kinase, muscle 0.0195145
USP3 ubiquitin specific peptidase 3 0.0195136
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.0195055
WDR4 WD repeat domain 4 0.019488
ATG5 autophagy related 5 0.0193595
PTPRA protein tyrosine phosphatase, receptor type, A 0.0193518
NOL9 nucleolar protein 9 0.0193322
FAM178B family with sequence similarity 178, member B 0.0193093
MROH1 maestro heat-like repeat family member 1 0.0192885
MECR mitochondrial trans-2-enoyl-CoA reductase 0.0192687
KDM2B lysine (K)-specific demethylase 2B 0.0192374
PDCD6IP programmed cell death 6 interacting protein 0.0192275
CLCN4 chloride channel, voltage-sensitive 4 0.019201
KIF15 kinesin family member 15 0.019179
TM9SF4 transmembrane 9 superfamily protein member 4 0.0191742
PLD3 phospholipase D family, member 3 0.0191654
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0191462
TCERG1 transcription elongation regulator 1 0.0191275
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0191253
CLIP1 CAP-GLY domain containing linker protein 1 0.0191127
SLC38A9 solute carrier family 38, member 9 0.0190901
PRKX protein kinase, X-linked 0.0190182
UBE3C ubiquitin protein ligase E3C 0.019
GATAD2B GATA zinc finger domain containing 2B 0.0189675
TPR translocated promoter region, nuclear basket protein 0.0189263
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.0188872
SFTPA2 surfactant protein A2 0.0188708
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0188681
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.0188441
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 0.0188376
TRA2A transformer 2 alpha homolog (Drosophila) 0.0188235
RPS10 ribosomal protein S10 0.0187561
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 0.0187531
PKNOX1 PBX/knotted 1 homeobox 1 0.0187056
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.0186682
PDCD11 programmed cell death 11 0.0185758
INTS7 integrator complex subunit 7 0.0185702
FAM117A family with sequence similarity 117, member A 0.0185468
DHRS7B dehydrogenase/reductase (SDR family) member 7B 0.0185401
TXNIP thioredoxin interacting protein 0.0185348
CD2AP CD2-associated protein 0.0185189
MAP7 microtubule-associated protein 7 0.0185162
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 0.0184555
NFIB nuclear factor I/B 0.0184499
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.0183986
SEC24A SEC24 family member A 0.0183945
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0183446
NCAPD3 non-SMC condensin II complex, subunit D3 0.0183402
FOXK2 forkhead box K2 0.0183152
DGCR2 DiGeorge syndrome critical region gene 2 0.0182983
KTN1 kinectin 1 (kinesin receptor) 0.0182965
RTL10 retrotransposon Gag like 10 0.0182781
FYTTD1 forty-two-three domain containing 1 0.018271
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0182625
AKAP10 A kinase (PRKA) anchor protein 10 0.0182498
ZNF24 zinc finger protein 24 0.0182184
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.0181665
TEX9 testis expressed 9 0.0181121
NLRP1 NLR family, pyrin domain containing 1 0.0181083
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0180812
PAXBP1 PAX3 and PAX7 binding protein 1 0.0180125
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.0179785
GOLGA3 golgin A3 0.0179719
ATRN attractin 0.017919
COPB1 coatomer protein complex, subunit beta 1 0.0178991
SH3GL1 SH3-domain GRB2-like 1 0.0178891
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0178425
EPB41 erythrocyte membrane protein band 4.1 0.0177922
GCC2 GRIP and coiled-coil domain containing 2 0.01778
AHI1 Abelson helper integration site 1 0.0177439
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.0177412
RAD21 RAD21 homolog (S. pombe) 0.0177115
C4ORF36 chromosome 4 open reading frame 36 0.0177025
TUBA1B tubulin, alpha 1b 0.0176889
DYM dymeclin 0.0176548
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0175888
NECTIN2 nectin cell adhesion molecule 2 0.0175531
TRIT1 tRNA isopentenyltransferase 1 0.0175018
RFX7 regulatory factor X, 7 0.017499
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0174926
PCNX1 pecanex 1 0.0174299
MRPS35 mitochondrial ribosomal protein S35 0.0174125
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.0173631
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0173612
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.0173249
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.017317
CCAR1 cell division cycle and apoptosis regulator 1 0.0172239
RPS9 ribosomal protein S9 0.0172125
SSRP1 structure specific recognition protein 1 0.0171912
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0171886
GAPVD1 GTPase activating protein and VPS9 domains 1 0.017187
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.0171661
SCAF4 SR-related CTD-associated factor 4 0.0171248
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0171237
ZER1 zyg-11 related, cell cycle regulator 0.0171115
SEC13 SEC13 homolog (S. cerevisiae) 0.017084
RPL19 ribosomal protein L19 0.0170715
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0170393
ANKRD12 ankyrin repeat domain 12 0.0169801
SOX5 SRY (sex determining region Y)-box 5 0.0169646
SURF4 surfeit 4 0.0169466
EIF3G eukaryotic translation initiation factor 3, subunit G 0.0169336
AFG1L AFG1 like ATPase 0.0169099
PTMS parathymosin 0.0168985
WDR82 WD repeat domain 82 0.0168565
CLASP2 cytoplasmic linker associated protein 2 0.0168523
LAPTM4B lysosomal protein transmembrane 4 beta 0.0168502
CNTRL centriolin 0.0168482
ACYP2 acylphosphatase 2, muscle type 0.0167839
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0167751
BMP7 bone morphogenetic protein 7 0.016732
RNF43 ring finger protein 43 0.0167003
RBM26 RNA binding motif protein 26 0.0166331
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0165693
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0165554
HSDL2 hydroxysteroid dehydrogenase like 2 0.0165352
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0165188
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0165187
ZDHHC17 zinc finger, DHHC-type containing 17 0.0165119
SENP1 SUMO1/sentrin specific peptidase 1 0.0165076
RORA RAR-related orphan receptor A 0.0164913
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0164765
MAPK9 mitogen-activated protein kinase 9 0.0164695
RPL10A ribosomal protein L10a 0.01644
CAVIN1 caveolae associated protein 1 0.016438
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0164368
ARB2A ARB2 cotranscriptional regulator A 0.0163709
FBL fibrillarin 0.0163656
ZC3H13 zinc finger CCCH-type containing 13 0.0163578
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0163057
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0162975
NKTR natural killer cell triggering receptor 0.0162956
MIER1 mesoderm induction early response 1, transcriptional regulator 0.0162952
ARHGAP35 Rho GTPase activating protein 35 0.0162547
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.016222
STK38 serine/threonine kinase 38 0.0161822
ZNF197 zinc finger protein 197 0.0161799
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0161593
TRIM27 tripartite motif containing 27 0.0161502
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.0161175
MORC3 MORC family CW-type zinc finger 3 0.0161134
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.0160931
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0160725
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0160692
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 0.016056
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.0160546
ZNF346 zinc finger protein 346 0.0160501
JAK1 Janus kinase 1 0.0160457
CSNK1G2 casein kinase 1, gamma 2 0.0160399
PCGF6 polycomb group ring finger 6 0.0160238
CCNT2 cyclin T2 0.0160161
USP45 ubiquitin specific peptidase 45 0.0160072
POGZ pogo transposable element with ZNF domain 0.0160071
GTF2B general transcription factor IIB 0.0160007
ASXL2 additional sex combs like transcriptional regulator 2 0.0160001
UBE2M ubiquitin-conjugating enzyme E2M 0.0159985
THUMPD2 THUMP domain containing 2 0.0159922
RAB5A RAB5A, member RAS oncogene family 0.0159434
FUBP3 far upstream element (FUSE) binding protein 3 0.0159254
UVRAG UV radiation resistance associated 0.0159231
EHBP1 EH domain binding protein 1 0.0158827
SLC39A9 solute carrier family 39, member 9 0.0158791
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0158684
ERP29 endoplasmic reticulum protein 29 0.0158652
ZNF490 zinc finger protein 490 0.0158032
RSL1D1 ribosomal L1 domain containing 1 0.0157754
ABHD12 abhydrolase domain containing 12 0.0157681
RUFY2 RUN and FYVE domain containing 2 0.0157679
FARSA phenylalanyl-tRNA synthetase, alpha subunit 0.0157601
VRK3 vaccinia related kinase 3 0.0157575
RHOBTB3 Rho-related BTB domain containing 3 0.0157327
PGK1 phosphoglycerate kinase 1 0.0157283
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.0156999
PPP1R8 protein phosphatase 1, regulatory subunit 8 0.0156438

decreased expression

Symbol Name Standardized Value
ARL15 ADP-ribosylation factor-like 15 -0.146117
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0871949
HBG2 hemoglobin, gamma G -0.0708097
MACF1 microtubule-actin crosslinking factor 1 -0.0685826
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0660195
GSE1 Gse1 coiled-coil protein -0.064723
FHIT fragile histidine triad -0.0572607
GPC5 glypican 5 -0.0562882
FDPS farnesyl diphosphate synthase -0.0560234
SUSD1 sushi domain containing 1 -0.0550534
RABGAP1L RAB GTPase activating protein 1-like -0.0545352
MEF2C myocyte enhancer factor 2C -0.0509796
STRN3 striatin, calmodulin binding protein 3 -0.0508301
PLCL1 phospholipase C-like 1 -0.0504173
PHACTR4 phosphatase and actin regulator 4 -0.0501072
PRKCB protein kinase C, beta -0.0495456
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0486206
SPATS2 spermatogenesis associated, serine-rich 2 -0.0482242
TGFB1 transforming growth factor, beta 1 -0.0481446
TET3 tet methylcytosine dioxygenase 3 -0.047928
SCARB1 scavenger receptor class B, member 1 -0.0474939
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0471234
ANKRD17 ankyrin repeat domain 17 -0.046868
LDLR low density lipoprotein receptor -0.0459839
TNPO3 transportin 3 -0.0456037
RANBP9 RAN binding protein 9 -0.0448649
LTBP1 latent transforming growth factor beta binding protein 1 -0.0447478
TBC1D5 TBC1 domain family, member 5 -0.0436874
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0430997
CEP350 centrosomal protein 350kDa -0.0425519
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0422561
MYO1D myosin ID -0.0415228
RPLP0 ribosomal protein, large, P0 -0.0406165
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.0400208
DIAPH1 diaphanous-related formin 1 -0.0389466
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0388157
SMYD3 SET and MYND domain containing 3 -0.0388056
HSPG2 heparan sulfate proteoglycan 2 -0.0387189
SGMS1 sphingomyelin synthase 1 -0.0382569
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0380652
ARHGAP21 Rho GTPase activating protein 21 -0.0374571
RPL30 ribosomal protein L30 -0.0372884
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0368516
MEIS2 Meis homeobox 2 -0.0364321
MICU1 mitochondrial calcium uptake 1 -0.0360818
CARD11 caspase recruitment domain family, member 11 -0.0353295
USP34 ubiquitin specific peptidase 34 -0.0352846
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0341057
CUX1 cut-like homeobox 1 -0.0339363
ZMYND8 zinc finger, MYND-type containing 8 -0.0337068
RC3H1 ring finger and CCCH-type domains 1 -0.0336214
RAB7A RAB7A, member RAS oncogene family -0.0336083
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.033484
BSG basigin (Ok blood group) -0.0333121
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0332536
IMMT inner membrane protein, mitochondrial -0.0324536
TTC28 tetratricopeptide repeat domain 28 -0.0321168
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0320988
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.032096
FASTKD1 FAST kinase domains 1 -0.0318281
TGFBR3 transforming growth factor, beta receptor III -0.0316582
CLASP1 cytoplasmic linker associated protein 1 -0.0316446
ASPH aspartate beta-hydroxylase -0.0316068
PPP1R9B protein phosphatase 1, regulatory subunit 9B -0.0311458
TPST2 tyrosylprotein sulfotransferase 2 -0.031038
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0307532
KDM5A lysine (K)-specific demethylase 5A -0.0307516
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.030589
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0304006
NCOR1 nuclear receptor corepressor 1 -0.0302131
JMJD1C jumonji domain containing 1C -0.0299661
TENT2 terminal nucleotidyltransferase 2 -0.0299018
WAC WW domain containing adaptor with coiled-coil -0.0297591
UBE2H ubiquitin-conjugating enzyme E2H -0.0297497
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0297491
MARCHF6 membrane associated ring-CH-type finger 6 -0.0294683
JARID2 jumonji, AT rich interactive domain 2 -0.0294213
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -0.0293581
TFCP2 transcription factor CP2 -0.029312
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -0.0291778
ZNF518A zinc finger protein 518A -0.0291568
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.028978
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0289011
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0286673
WSB1 WD repeat and SOCS box containing 1 -0.0286471
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0285299
ECPAS Ecm29 proteasome adaptor and scaffold -0.0285179
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0285029
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0284838
TMEM131 transmembrane protein 131 -0.0283516
ADGRV1 adhesion G protein-coupled receptor V1 -0.0282402
QSER1 glutamine and serine rich 1 -0.0281969
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0281288
PFKP phosphofructokinase, platelet -0.0280145
TFR2 transferrin receptor 2 -0.0279696
ZNF292 zinc finger protein 292 -0.0278733
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0277133
CD44 CD44 molecule (Indian blood group) -0.0276468
YTHDC2 YTH domain containing 2 -0.0276258
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0274085
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -0.0273711
DTNBP1 dystrobrevin binding protein 1 -0.0271239
BTBD7 BTB (POZ) domain containing 7 -0.0270986
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0270326
ITGAV integrin, alpha V -0.0270245
SOX6 SRY (sex determining region Y)-box 6 -0.0269869
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.026893
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.026877
ADGRE2 adhesion G protein-coupled receptor E2 -0.0268209
VWDE von Willebrand factor D and EGF domains -0.0266893
GSK3B glycogen synthase kinase 3 beta -0.0265794
ASF1B anti-silencing function 1B histone chaperone -0.0265496
ZYG11B zyg-11 family member B, cell cycle regulator -0.0265278
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0264367
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0263228
FUS FUS RNA binding protein -0.0257655
HBG1 hemoglobin, gamma A -0.0257592
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0257027
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.02564
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0254759
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0252527
EIF3M eukaryotic translation initiation factor 3, subunit M -0.0252466
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.0251874
NALF1 NALCN channel auxiliary factor 1 -0.0250382
DGCR8 DGCR8 microprocessor complex subunit -0.0250011
CNTNAP2 contactin associated protein-like 2 -0.0249471
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0249264
ITCH itchy E3 ubiquitin protein ligase -0.0248345
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0248209
BCL2L1 BCL2-like 1 -0.0246803
SCFD2 sec1 family domain containing 2 -0.0244267
TMEM181 transmembrane protein 181 -0.0243898
USP6NL USP6 N-terminal like -0.0243875
CENPC centromere protein C -0.0243615
INSIG1 insulin induced gene 1 -0.0242782
VTA1 vesicle (multivesicular body) trafficking 1 -0.0241913
FANCC Fanconi anemia, complementation group C -0.0241713
PRRC2B proline-rich coiled-coil 2B -0.0241503
RNF38 ring finger protein 38 -0.0241421
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0240654
MRTFA myocardin related transcription factor A -0.0240027
VCL vinculin -0.0239937
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.0238931
RACK1 receptor for activated C kinase 1 -0.0238554
FBXL20 F-box and leucine-rich repeat protein 20 -0.0238299
CFAP161 cilia and flagella associated protein 161 -0.0237985
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0235988
RHOT1 ras homolog family member T1 -0.0235769
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0234138
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.023404
NIBAN1 niban apoptosis regulator 1 -0.0233262
MCFD2 multiple coagulation factor deficiency 2 -0.0233026
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0232735
NPAT nuclear protein, ataxia-telangiectasia locus -0.0232173
DROSHA drosha, ribonuclease type III -0.0230124
HDAC4 histone deacetylase 4 -0.0229545
CLIP2 CAP-GLY domain containing linker protein 2 -0.0229387
NEB nebulin -0.0228734
KAT6A K(lysine) acetyltransferase 6A -0.0228713
ZEB2 zinc finger E-box binding homeobox 2 -0.0227889
PPA2 pyrophosphatase (inorganic) 2 -0.0227681
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 -0.0227551
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0226495
DCP1A decapping mRNA 1A -0.0225247
CAPNS1 calpain, small subunit 1 -0.022502
CORO2A coronin, actin binding protein, 2A -0.0223703
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0223147
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0222594
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -0.0221937
RREB1 ras responsive element binding protein 1 -0.0221929
H2AZ2 H2A.Z variant histone 2 -0.02217
GMPR guanosine monophosphate reductase -0.0220693
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0220633
CMC1 C-x(9)-C motif containing 1 -0.0220245
RBL1 retinoblastoma-like 1 -0.021966
FAM13A family with sequence similarity 13, member A -0.0219332
PTH2R parathyroid hormone 2 receptor -0.0218874
ATXN7L1 ataxin 7-like 1 -0.0217704
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0217308
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -0.021726
CDC27 cell division cycle 27 -0.0216814
FKBP15 FK506 binding protein 15, 133kDa -0.0216638
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0215965
STAG2 stromal antigen 2 -0.0215857
TPM3 tropomyosin 3 -0.0215312
CADM2 cell adhesion molecule 2 -0.0214889
ELL2 elongation factor, RNA polymerase II, 2 -0.0214764
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0214228
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.0213206
ADGRB3 adhesion G protein-coupled receptor B3 -0.021279
ARHGAP15 Rho GTPase activating protein 15 -0.0212634
SPPL3 signal peptide peptidase like 3 -0.0212077
TCF12 transcription factor 12 -0.021086
KDM4B lysine (K)-specific demethylase 4B -0.0210736
NCOA4 nuclear receptor coactivator 4 -0.0209843
FAM13B family with sequence similarity 13, member B -0.0209599
CCDC57 coiled-coil domain containing 57 -0.0209591
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0209503
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0208393
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -0.0208255
TMEM165 transmembrane protein 165 -0.0208157
CPEB3 cytoplasmic polyadenylation element binding protein 3 -0.0208121
CDK12 cyclin-dependent kinase 12 -0.0208105
LUC7L LUC7-like (S. cerevisiae) -0.020781
DCAF10 DDB1 and CUL4 associated factor 10 -0.0207215
KRT19 keratin 19, type I -0.0206573
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0206195
LUZP1 leucine zipper protein 1 -0.0205861
PGPEP1 pyroglutamyl-peptidase I -0.0205688
EFL1 elongation factor like GTPase 1 -0.0205627
RPS8 ribosomal protein S8 -0.0204417
AHCYL2 adenosylhomocysteinase-like 2 -0.0203931
ECI1 enoyl-CoA delta isomerase 1 -0.0203728
RNF115 ring finger protein 115 -0.0203579
GEN1 GEN1 Holliday junction 5' flap endonuclease -0.0203289
CDIN1 CDAN1 interacting nuclease 1 -0.020324
SRPK2 SRSF protein kinase 2 -0.0203007
TFRC transferrin receptor -0.0202327
BCR breakpoint cluster region -0.0202255
ARHGAP11B Rho GTPase activating protein 11B -0.020195
CDCP1 CUB domain containing protein 1 -0.020165
AAK1 AP2 associated kinase 1 -0.0201381
PARN poly(A)-specific ribonuclease -0.0201306
NLN neurolysin (metallopeptidase M3 family) -0.0200816
AGO1 argonaute RISC catalytic component 1 -0.0199859
SLC25A42 solute carrier family 25, member 42 -0.0199807
FBXO28 F-box protein 28 -0.0199699
TRIM24 tripartite motif containing 24 -0.0198467
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.019816
BST2 bone marrow stromal cell antigen 2 -0.0197511
STRIP2 striatin interacting protein 2 -0.019732
FOXJ3 forkhead box J3 -0.0196964
RPSA ribosomal protein SA -0.0196349
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.0195674
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0195596
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0195453
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.019532
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0195096
ZNF326 zinc finger protein 326 -0.0194723
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0194249
LNPEP leucyl/cystinyl aminopeptidase -0.0193947
ADGRE5 adhesion G protein-coupled receptor E5 -0.0193782
SOGA1 suppressor of glucose, autophagy associated 1 -0.0193323
CDC14A cell division cycle 14A -0.0193147
RPL22 ribosomal protein L22 -0.0193119
UBXN7 UBX domain protein 7 -0.0192813
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0192368
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0192042
CCSER2 coiled-coil serine-rich protein 2 -0.0191944
KIF11 kinesin family member 11 -0.019164
PRAME preferentially expressed antigen in melanoma -0.0191263
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0190555
FMNL3 formin-like 3 -0.0190554
EXOC3L2 exocyst complex component 3-like 2 -0.0189805
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0189775
AFF4 AF4/FMR2 family, member 4 -0.018969
ZFPM2 zinc finger protein, FOG family member 2 -0.0189457
ZNF83 zinc finger protein 83 -0.018944
STX5 syntaxin 5 -0.0189386
FANCA Fanconi anemia, complementation group A -0.0189306
COTL1 coactosin-like F-actin binding protein 1 -0.018883
ZC3H4 zinc finger CCCH-type containing 4 -0.0188039
ACO2 aconitase 2, mitochondrial -0.0187746
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0187688
QPCTL glutaminyl-peptide cyclotransferase-like -0.018743
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0187137
COP1 COP1 E3 ubiquitin ligase -0.0186681
RSRP1 arginine/serine-rich protein 1 -0.0185759
CDC73 cell division cycle 73 -0.0185599
STXBP3 syntaxin binding protein 3 -0.0185215
TXNRD1 thioredoxin reductase 1 -0.0185194
ACBD6 acyl-CoA binding domain containing 6 -0.0184193
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.0183962
COX5B cytochrome c oxidase subunit Vb -0.0183837
CAMTA1 calmodulin binding transcription activator 1 -0.0183294
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0182814
SYNGR2 synaptogyrin 2 -0.0182621
RFWD3 ring finger and WD repeat domain 3 -0.0182482
ANXA2 annexin A2 -0.0181645
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -0.0181631
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.0180512
STXBP4 syntaxin binding protein 4 -0.0180494
IGFBP5 insulin-like growth factor binding protein 5 -0.0179648
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0179289
GTF2IRD1 GTF2I repeat domain containing 1 -0.0179282
CSMD1 CUB and Sushi multiple domains 1 -0.0179221
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0178735
UBE3A ubiquitin protein ligase E3A -0.0178687
PFDN1 prefoldin subunit 1 -0.0178329
CIZ1 CDKN1A interacting zinc finger protein 1 -0.0177506
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0177048
CA8 carbonic anhydrase VIII -0.0176612
WDR12 WD repeat domain 12 -0.0176017
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -0.0175794
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.017506
BZW2 basic leucine zipper and W2 domains 2 -0.0174908
DENND1B DENN/MADD domain containing 1B -0.0174724
TXK TXK tyrosine kinase -0.0174399
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0174038
GOLGA4 golgin A4 -0.0173691
CTBP2 C-terminal binding protein 2 -0.0173689
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0172815
WDR33 WD repeat domain 33 -0.0172414
KIF13A kinesin family member 13A -0.0172076
KAZN kazrin, periplakin interacting protein -0.0171462
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.0170744
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0170643
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.017052
MEPCE methylphosphate capping enzyme -0.0170426
RBM20 RNA binding motif protein 20 -0.0169941
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -0.0169621
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0169201
TRAPPC9 trafficking protein particle complex 9 -0.01685
CLIC2 chloride intracellular channel 2 -0.0167876
MACROD1 MACRO domain containing 1 -0.0167801
CSNK1D casein kinase 1, delta -0.0167719
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.0167626
DENND5A DENN/MADD domain containing 5A -0.0167519
ABI1 abl-interactor 1 -0.0167513
UNKL unkempt family zinc finger-like -0.016742
CCDC88A coiled-coil domain containing 88A -0.0167356
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.016727
GATAD1 GATA zinc finger domain containing 1 -0.0166999
RNASE3 ribonuclease, RNase A family, 3 -0.0166709
BCCIP BRCA2 and CDKN1A interacting protein -0.016669
SRSF11 serine/arginine-rich splicing factor 11 -0.016651
PDZD8 PDZ domain containing 8 -0.0166431
AGO3 argonaute RISC catalytic component 3 -0.0166325
HPCAL1 hippocalcin-like 1 -0.0166114
UBN1 ubinuclein 1 -0.0166028
SLMAP sarcolemma associated protein -0.0165272
WHRN whirlin -0.0165137
PHF20 PHD finger protein 20 -0.0165126
NAP1L4 nucleosome assembly protein 1-like 4 -0.0164631
ICA1 islet cell autoantigen 1, 69kDa -0.016456
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.0164466
COMMD10 COMM domain containing 10 -0.0164311
RANBP10 RAN binding protein 10 -0.0163586
PNKP polynucleotide kinase 3'-phosphatase -0.0163503
OTUD5 OTU deubiquitinase 5 -0.0163272
MGST1 microsomal glutathione S-transferase 1 -0.0163134
LPIN1 lipin 1 -0.0163112
CUL2 cullin 2 -0.0163017
SENP7 SUMO1/sentrin specific peptidase 7 -0.0162818
KIAA2026 KIAA2026 -0.0162736
ZFX zinc finger protein, X-linked -0.0162049
FNDC3B fibronectin type III domain containing 3B -0.0161744
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0161633
SEH1L SEH1-like (S. cerevisiae) -0.016148
UBE3D ubiquitin protein ligase E3D -0.0161286
HBA1 hemoglobin, alpha 1 -0.0161026
DAND5 DAN domain family member 5, BMP antagonist -0.0160844
FKBP8 FK506 binding protein 8, 38kDa -0.0160498
STARD3 StAR-related lipid transfer (START) domain containing 3 -0.0160492
LMAN2L lectin, mannose-binding 2-like -0.0160221
RPL7 ribosomal protein L7 -0.0160145
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.016007
SLC39A11 solute carrier family 39, member 11 -0.015983
FKBP5 FK506 binding protein 5 -0.0159827
BLVRB biliverdin reductase B -0.015973
RNF215 ring finger protein 215 -0.0159461
RBM19 RNA binding motif protein 19 -0.0158839
GTF2I general transcription factor IIi -0.0158587
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -0.0158553
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -0.0158458
VAC14 Vac14 homolog (S. cerevisiae) -0.0158264
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -0.0158155
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0158137
RHBDD2 rhomboid domain containing 2 -0.0158081
CREB1 cAMP responsive element binding protein 1 -0.0157785
XPO4 exportin 4 -0.0157659
NDC1 NDC1 transmembrane nucleoporin -0.0157653
GFOD2 glucose-fructose oxidoreductase domain containing 2 -0.0157616
CAPN2 calpain 2, (m/II) large subunit -0.0157054
ARHGAP17 Rho GTPase activating protein 17 -0.0156848
SOD2 superoxide dismutase 2, mitochondrial -0.0156665
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0156508
TMEM41B transmembrane protein 41B -0.0156492
SEPTIN6 septin 6 -0.0156479
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.0156403
EIPR1 EARP complex and GARP complex interacting protein 1 -0.0156028
ZNF318 zinc finger protein 318 -0.0155753
SEPTIN9 septin 9 -0.0155682
IGSF1 immunoglobulin superfamily, member 1 -0.0155103
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.0154976
HOOK2 hook microtubule-tethering protein 2 -0.0154268
NEBL nebulette -0.0154137
MBNL1 muscleblind-like splicing regulator 1 -0.0154041
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0153983
SH2B3 SH2B adaptor protein 3 -0.0153945
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -0.0153617
SETD2 SET domain containing 2 -0.0153454
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -0.0153437
HBE1 hemoglobin, epsilon 1 -0.0153025
PLCD1 phospholipase C, delta 1 -0.0152997
IFT74 intraflagellar transport 74 -0.0152825
MPZL1 myelin protein zero-like 1 -0.0152615
SFPQ splicing factor proline/glutamine-rich -0.0152354
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -0.0152235
SSR4 signal sequence receptor, delta -0.015217
TMEM245 transmembrane protein 245 -0.015204
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0151795
STAU2 staufen double-stranded RNA binding protein 2 -0.0151789
CENPE centromere protein E, 312kDa -0.0151492
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -0.0151392
XPC xeroderma pigmentosum, complementation group C -0.0151301
SEPTIN11 septin 11 -0.0151223
UBL4A ubiquitin-like 4A -0.0151169
RRM1 ribonucleotide reductase M1 -0.0150926
FRS2 fibroblast growth factor receptor substrate 2 -0.015088
WDFY2 WD repeat and FYVE domain containing 2 -0.0150796
ZNF431 zinc finger protein 431 -0.0150443
MSL2 male-specific lethal 2 homolog (Drosophila) -0.0149944
CSPP1 centrosome and spindle pole associated protein 1 -0.0149636
PARD3B par-3 family cell polarity regulator beta -0.0149345
RPL18 ribosomal protein L18 -0.0149338
THADA thyroid adenoma associated -0.0149142
HMBOX1 homeobox containing 1 -0.0148665
JPT1 Jupiter microtubule associated homolog 1 -0.0148487
AHDC1 AT hook, DNA binding motif, containing 1 -0.0148461
SREBF2 sterol regulatory element binding transcription factor 2 -0.0148372
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0148205
TUBA1C tubulin, alpha 1c -0.0148167
FRRS1 ferric-chelate reductase 1 -0.0148093
LCOR ligand dependent nuclear receptor corepressor -0.0147866
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0147516
GIPR gastric inhibitory polypeptide receptor -0.0147144
ZNF394 zinc finger protein 394 -0.0147051
HMGN1 high mobility group nucleosome binding domain 1 -0.014666
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -0.014638
MCM4 minichromosome maintenance complex component 4 -0.0146333
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0146056
PPP4R2 protein phosphatase 4, regulatory subunit 2 -0.0145808
GOLPH3L golgi phosphoprotein 3-like -0.0145337
IGSF3 immunoglobulin superfamily, member 3 -0.0145275
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0145247
SPAG5 sperm associated antigen 5 -0.0145147
RAP1B RAP1B, member of RAS oncogene family -0.0144991
FOSL1 FOS-like antigen 1 -0.0144971
TGM2 transglutaminase 2 -0.0144963
SRSF10 serine/arginine-rich splicing factor 10 -0.0144786
CUL1 cullin 1 -0.014476
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.014466
FBH1 F-box DNA helicase 1 -0.0144552
SERINC5 serine incorporator 5 -0.0144515
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -0.0144495
ANKMY1 ankyrin repeat and MYND domain containing 1 -0.0143695
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0143608
DLK1 delta-like 1 homolog (Drosophila) -0.0143445
PRPF4B pre-mRNA processing factor 4B -0.014298
HOOK3 hook microtubule-tethering protein 3 -0.0142936
SLX4IP SLX4 interacting protein -0.0142885
KLHDC4 kelch domain containing 4 -0.0142838
ARHGAP25 Rho GTPase activating protein 25 -0.0142742
IL16 interleukin 16 -0.0142717
USP33 ubiquitin specific peptidase 33 -0.0142416
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -0.0141757
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0141689
WRN Werner syndrome, RecQ helicase-like -0.0141395
TTC7B tetratricopeptide repeat domain 7B -0.0141348
DSCAM Down syndrome cell adhesion molecule -0.014113
SCAMP2 secretory carrier membrane protein 2 -0.0141095
SENP6 SUMO1/sentrin specific peptidase 6 -0.0140987
RBM12B RNA binding motif protein 12B -0.0140826
PNKD paroxysmal nonkinesigenic dyskinesia -0.0140474
SAP30BP SAP30 binding protein -0.0140347
FLNB filamin B, beta -0.014034
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0140249
ZNF407 zinc finger protein 407 -0.0140245
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -0.0140152
WNK1 WNK lysine deficient protein kinase 1 -0.0139832
VPS35L VPS35 endosomal protein sorting factor like -0.0139825
BICRAL BICRA like chromatin remodeling complex associated protein -0.0139809
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0139618
FKBP1A FK506 binding protein 1A, 12kDa -0.0139514
UTRN utrophin -0.0139347
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.0139342
MDH1 malate dehydrogenase 1, NAD (soluble) -0.0138985
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -0.0138866
C1ORF159 chromosome 1 open reading frame 159 -0.0138409
KNTC1 kinetochore associated 1 -0.0138387
TMEM135 transmembrane protein 135 -0.0138302
ZNF195 zinc finger protein 195 -0.0138272
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.013818
PCSK7 proprotein convertase subtilisin/kexin type 7 -0.0138119
DENND4C DENN/MADD domain containing 4C -0.0137984
TBPL1 TBP-like 1 -0.0137902
ACBD3 acyl-CoA binding domain containing 3 -0.0137843
RUBCN rubicon autophagy regulator -0.0137814
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 -0.0137738
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -0.0137697
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0137656
ZDHHC5 zinc finger, DHHC-type containing 5 -0.013759
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -0.0137487
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0137455
PHKB phosphorylase kinase, beta -0.0137119
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0136861
ITGB5 integrin, beta 5 -0.0136842
ZBTB44 zinc finger and BTB domain containing 44 -0.0136651
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.0136397