K562_GSK J1_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 1µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK J1_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
CENPF centromere protein F, 350/400kDa 0.0985783
GSE1 Gse1 coiled-coil protein 0.0816386
USP34 ubiquitin specific peptidase 34 0.0729016
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0645138
ARHGAP21 Rho GTPase activating protein 21 0.0625238
TLK1 tousled-like kinase 1 0.0617969
FHIT fragile histidine triad 0.0607902
MTDH metadherin 0.0563041
MKI67 marker of proliferation Ki-67 0.056019
ZFPM2 zinc finger protein, FOG family member 2 0.0519459
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0514783
BCOR BCL6 corepressor 0.0465946
OLA1 Obg-like ATPase 1 0.045985
GON4L gon-4-like (C. elegans) 0.0458765
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0455257
ARHGAP6 Rho GTPase activating protein 6 0.0448839
RARS1 arginyl-tRNA synthetase 1 0.0444781
RPL13A ribosomal protein L13a 0.0444455
CALU calumenin 0.0442521
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.04407
LRPPRC leucine-rich pentatricopeptide repeat containing 0.043957
PHIP pleckstrin homology domain interacting protein 0.0438453
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0433053
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0432204
CPED1 cadherin-like and PC-esterase domain containing 1 0.0427459
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.0424398
AGO3 argonaute RISC catalytic component 3 0.0413529
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0411043
SIK3 SIK family kinase 3 0.0411019
UBTF upstream binding transcription factor, RNA polymerase I 0.0404174
ADAM17 ADAM metallopeptidase domain 17 0.0394011
PARD3B par-3 family cell polarity regulator beta 0.039112
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0389171
AIG1 androgen-induced 1 0.0386262
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0385713
UBE3C ubiquitin protein ligase E3C 0.0385
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0384832
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0384135
RNF4 ring finger protein 4 0.0379523
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0374492
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0373838
LEPROT leptin receptor overlapping transcript 0.0372351
ATG7 autophagy related 7 0.0368813
ZFAND3 zinc finger, AN1-type domain 3 0.0366451
CCDC91 coiled-coil domain containing 91 0.0365317
MYO19 myosin XIX 0.0362314
QRICH1 glutamine-rich 1 0.0361702
RBM15 RNA binding motif protein 15 0.0360289
FAM222B family with sequence similarity 222, member B 0.035961
SORT1 sortilin 1 0.0357374
NUP160 nucleoporin 160kDa 0.0356591
BSG basigin (Ok blood group) 0.0355359
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.035516
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0347751
SLC38A2 solute carrier family 38, member 2 0.0347517
RAB10 RAB10, member RAS oncogene family 0.0347424
WT1 Wilms tumor 1 0.0346271
CDYL chromodomain protein, Y-like 0.0343713
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0343603
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0342316
ZMYND8 zinc finger, MYND-type containing 8 0.0342088
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.0338622
CHEK1 checkpoint kinase 1 0.033721
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 0.0337075
USP47 ubiquitin specific peptidase 47 0.0336125
AFG2A AFG2 AAA ATPase homolog A 0.0333648
RABGAP1L RAB GTPase activating protein 1-like 0.0333614
PRKCA protein kinase C, alpha 0.0332778
MED13 mediator complex subunit 13 0.0331175
MUSK muscle, skeletal, receptor tyrosine kinase 0.0330791
BID BH3 interacting domain death agonist 0.0328927
FER fer (fps/fes related) tyrosine kinase 0.0328607
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.032747
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0327447
RTN4 reticulon 4 0.0326909
SRRM1 serine/arginine repetitive matrix 1 0.0326
NMU neuromedin U 0.0325373
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.0323557
CD53 CD53 molecule 0.0322951
CNST consortin, connexin sorting protein 0.0322307
RAP1A RAP1A, member of RAS oncogene family 0.0322129
CENPE centromere protein E, 312kDa 0.0319701
LMNA lamin A/C 0.0319631
AKAP9 A kinase (PRKA) anchor protein 9 0.0319002
FLOT1 flotillin 1 0.031886
ZNF106 zinc finger protein 106 0.0317673
PCNT pericentrin 0.0317047
KMT2A lysine (K)-specific methyltransferase 2A 0.0314394
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0313772
ELOVL5 ELOVL fatty acid elongase 5 0.0313527
PTGES2 prostaglandin E synthase 2 0.0310671
NBAS neuroblastoma amplified sequence 0.0310221
SKA2 spindle and kinetochore associated complex subunit 2 0.0309975
SPTBN2 spectrin, beta, non-erythrocytic 2 0.0309841
U2SURP U2 snRNP-associated SURP domain containing 0.0309535
WDR4 WD repeat domain 4 0.0309329
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0308902
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0308677
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0307473
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0306203
SPAG9 sperm associated antigen 9 0.0302473
NADK NAD kinase 0.0301871
RAB1A RAB1A, member RAS oncogene family 0.0298127
LYRM4 LYR motif containing 4 0.0296086
ADAMTSL4 ADAMTS-like 4 0.0293155
PRAME preferentially expressed antigen in melanoma 0.0292657
PDE4A phosphodiesterase 4A, cAMP-specific 0.0292456
CEP192 centrosomal protein 192kDa 0.0291976
KRT19 keratin 19, type I 0.0290994
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0289693
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 0.0289542
RELN reelin 0.028881
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0288323
SMG5 SMG5 nonsense mediated mRNA decay factor 0.0286617
NOSTRIN nitric oxide synthase trafficking 0.0285028
CEP290 centrosomal protein 290kDa 0.0284858
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.0284778
LUC7L LUC7-like (S. cerevisiae) 0.0284654
SMC4 structural maintenance of chromosomes 4 0.0284334
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0281779
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0281348
RHOBTB3 Rho-related BTB domain containing 3 0.0280888
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0280608
CCSER2 coiled-coil serine-rich protein 2 0.0280211
ARID1A AT rich interactive domain 1A (SWI-like) 0.0280033
MICU2 mitochondrial calcium uptake 2 0.027773
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0276794
ABHD12 abhydrolase domain containing 12 0.0276154
TFRC transferrin receptor 0.0275584
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.0274711
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0274658
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.027455
SEPTIN6 septin 6 0.0274354
SCAF11 SR-related CTD-associated factor 11 0.0273067
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.0272415
RBBP6 retinoblastoma binding protein 6 0.0271754
RPL37A ribosomal protein L37a 0.0269523
CALN1 calneuron 1 0.026881
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0266444
CUX1 cut-like homeobox 1 0.0266232
NDC1 NDC1 transmembrane nucleoporin 0.026528
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0264143
WDR70 WD repeat domain 70 0.0264063
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0263823
PTBP2 polypyrimidine tract binding protein 2 0.0263698
MAML2 mastermind-like 2 (Drosophila) 0.0262772
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.0262312
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.0261411
ARTN artemin 0.026127
XPO7 exportin 7 0.0260315
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0260001
KAZN kazrin, periplakin interacting protein 0.0258947
FNDC3B fibronectin type III domain containing 3B 0.0257668
RACK1 receptor for activated C kinase 1 0.0256329
CHD6 chromodomain helicase DNA binding protein 6 0.025619
MRTFA myocardin related transcription factor A 0.0255799
PEAK1 pseudopodium-enriched atypical kinase 1 0.0255643
YDJC YdjC homolog (bacterial) 0.0254869
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0254705
PLIN3 perilipin 3 0.0254507
ATXN2L ataxin 2-like 0.0253884
DSTN destrin (actin depolymerizing factor) 0.0253737
NCKAP1 NCK-associated protein 1 0.025373
ECD ecdysoneless homolog (Drosophila) 0.0253458
SOS1 son of sevenless homolog 1 (Drosophila) 0.025319
SCFD2 sec1 family domain containing 2 0.0251657
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.0251606
UGCG UDP-glucose ceramide glucosyltransferase 0.0251598
TMEM131 transmembrane protein 131 0.0251211
FYN FYN proto-oncogene, Src family tyrosine kinase 0.0250852
RBSN rabenosyn, RAB effector 0.0250712
HBG1 hemoglobin, gamma A 0.0250292
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0250052
EIF3K eukaryotic translation initiation factor 3, subunit K 0.02481
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0247401
PRDX5 peroxiredoxin 5 0.0245827
DSCAM Down syndrome cell adhesion molecule 0.0245348
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.0244867
CMC1 C-x(9)-C motif containing 1 0.0244502
VDAC2 voltage-dependent anion channel 2 0.0243756
HDGF hepatoma-derived growth factor 0.0243274
SLC35E2B solute carrier family 35, member E2B 0.0242151
NUCB1 nucleobindin 1 0.024168
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0241619
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0241576
TMOD3 tropomodulin 3 (ubiquitous) 0.0240708
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0240096
RPS17 ribosomal protein S17 0.0239684
METTL15 methyltransferase like 15 0.0239413
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0239395
CORO1C coronin, actin binding protein, 1C 0.0239011
CREB1 cAMP responsive element binding protein 1 0.0238141
CANX calnexin 0.0237997
NAP1L4 nucleosome assembly protein 1-like 4 0.0237853
NBEAL1 neurobeachin-like 1 0.0237153
RSF1 remodeling and spacing factor 1 0.0236808
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0236405
MEF2A myocyte enhancer factor 2A 0.0236273
TUBB tubulin, beta class I 0.0235868
UBL4A ubiquitin-like 4A 0.0235619
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.0235261
TCP1 t-complex 1 0.0235192
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0234442
PHACTR2 phosphatase and actin regulator 2 0.0234389
NKTR natural killer cell triggering receptor 0.0234199
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0233579
SACK1A scaffolding CK1 anchoring protein A 0.0233364
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0232873
MRPL4 mitochondrial ribosomal protein L4 0.0232836
IPO7 importin 7 0.023275
TMEM41B transmembrane protein 41B 0.0232724
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.023268
SNX9 sorting nexin 9 0.0232405
IARS1 isoleucyl-tRNA synthetase 1 0.023121
NDC80 NDC80 kinetochore complex component 0.0231079
FAM13A family with sequence similarity 13, member A 0.022935
USP9X ubiquitin specific peptidase 9, X-linked 0.0229026
XPO6 exportin 6 0.0228824
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.0227956
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.0227693
TNRC18 trinucleotide repeat containing 18 0.0227657
ECI1 enoyl-CoA delta isomerase 1 0.022658
AHCYL1 adenosylhomocysteinase-like 1 0.0226518
KDM4C lysine (K)-specific demethylase 4C 0.0225828
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0225573
BFAR bifunctional apoptosis regulator 0.0224865
PACS1 phosphofurin acidic cluster sorting protein 1 0.0224601
SLC44A5 solute carrier family 44, member 5 0.0224494
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.0224011
ZC3H7B zinc finger CCCH-type containing 7B 0.0223713
SAP130 Sin3A-associated protein, 130kDa 0.0223689
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.0223621
KIF13A kinesin family member 13A 0.0222864
NEBL nebulette 0.0222476
SRSF7 serine/arginine-rich splicing factor 7 0.0222172
CEP20 centrosomal protein 20 0.0222159
CCAR1 cell division cycle and apoptosis regulator 1 0.0221773
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 0.022087
SRRM2 serine/arginine repetitive matrix 2 0.0220398
PGK1 phosphoglycerate kinase 1 0.0220272
RBM33 RNA binding motif protein 33 0.021939
WASL Wiskott-Aldrich syndrome-like 0.0219351
RPN2 ribophorin II 0.0219294
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0218787
BLTP2 bridge-like lipid transfer protein family member 2 0.0218459
DCAF17 DDB1 and CUL4 associated factor 17 0.0218079
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0217672
RBM26 RNA binding motif protein 26 0.0217437
AFDN afadin, adherens junction formation factor 0.0217265
CNOT2 CCR4-NOT transcription complex, subunit 2 0.0217234
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.0217095
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0216667
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.021651
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.0215923
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0215745
PRPF6 pre-mRNA processing factor 6 0.0215427
SERTAD2 SERTA domain containing 2 0.0215141
CUL5 cullin 5 0.021463
RSL1D1 ribosomal L1 domain containing 1 0.0214588
DYNC2I1 dynein 2 intermediate chain 1 0.0213401
SATB2 SATB homeobox 2 0.0212197
SENP6 SUMO1/sentrin specific peptidase 6 0.0212196
DCP1A decapping mRNA 1A 0.0212083
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.021154
ZNF638 zinc finger protein 638 0.0211051
CTPS2 CTP synthase 2 0.0211046
SLC39A11 solute carrier family 39, member 11 0.0210994
ZNF431 zinc finger protein 431 0.0210951
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.020971
XRRA1 X-ray radiation resistance associated 1 0.0209537
KIF2A kinesin heavy chain member 2A 0.020865
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0208499
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0207487
RPLP1 ribosomal protein, large, P1 0.0207388
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.0206609
FLNC filamin C, gamma 0.0206479
MTFR1 mitochondrial fission regulator 1 0.0206462
CNOT6 CCR4-NOT transcription complex, subunit 6 0.0206117
KLHDC10 kelch domain containing 10 0.0206054
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.0205346
WDR36 WD repeat domain 36 0.020494
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.0204491
RANGAP1 Ran GTPase activating protein 1 0.0204172
LRRC8A leucine rich repeat containing 8 family, member A 0.0203347
BRD2 bromodomain containing 2 0.0202908
UBN2 ubinuclein 2 0.0202864
IRF3 interferon regulatory factor 3 0.0202671
ZBTB35 zinc finger and BTB domain containing 35 0.0202567
IL12RB2 interleukin 12 receptor, beta 2 0.0202223
PSME3IP1 proteasome activator subunit 3 interacting protein 1 0.02022
RPS11 ribosomal protein S11 0.0202178
PDCD11 programmed cell death 11 0.0201716
DENND1B DENN/MADD domain containing 1B 0.0201344
SAMD1 sterile alpha motif domain containing 1 0.0201284
MOV10 Mov10 RISC complex RNA helicase 0.0201248
IWS1 IWS1 homolog (S. cerevisiae) 0.0201091
PRKX protein kinase, X-linked 0.0200951
FAM117B family with sequence similarity 117, member B 0.0200799
SASH1 SAM and SH3 domain containing 1 0.0200539
RILPL2 Rab interacting lysosomal protein-like 2 0.0200316
LMAN1 lectin, mannose-binding, 1 0.0200314
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0199849
WDR1 WD repeat domain 1 0.0199312
TXN2 thioredoxin 2 0.0199195
PDZD8 PDZ domain containing 8 0.0198768
FANCI Fanconi anemia, complementation group I 0.019863
YARS1 tyrosyl-tRNA synthetase 1 0.01985
COASY CoA synthase 0.0197917
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.0197751
BICD1 bicaudal D homolog 1 (Drosophila) 0.0197624
DOK7 docking protein 7 0.0197421
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0197399
AVL9 AVL9 homolog (S. cerevisiase) 0.0197225
CLIC1 chloride intracellular channel 1 0.0197013
MED13L mediator complex subunit 13-like 0.0196935
DPY19L4 dpy-19-like 4 (C. elegans) 0.0196849
NRIP1 nuclear receptor interacting protein 1 0.0196361
RPL32 ribosomal protein L32 0.0195343
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 0.0194516
KLHL8 kelch-like family member 8 0.0194094
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0193606
PPARD peroxisome proliferator-activated receptor delta 0.0193513
IMMT inner membrane protein, mitochondrial 0.0193292
FAM133B family with sequence similarity 133, member B 0.0193195
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0193047
FUS FUS RNA binding protein 0.0192707
NPAT nuclear protein, ataxia-telangiectasia locus 0.0192386
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0192185
CENPB centromere protein B, 80kDa 0.0192132
PGAP2 post-GPI attachment to proteins 2 0.0191996
RPL10A ribosomal protein L10a 0.0191705
PKN3 protein kinase N3 0.019138
MYADM myeloid-associated differentiation marker 0.0191271
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0190488
CNOT9 CCR4-NOT transcription complex subunit 9 0.0190452
AHCTF1 AT hook containing transcription factor 1 0.0190207
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.019016
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0190008
CYRIB CYFIP related Rac1 interactor B 0.0189419
BRD1 bromodomain containing 1 0.0189352
RPL12 ribosomal protein L12 0.0189259
DHDDS dehydrodolichyl diphosphate synthase 0.0188882
DCP2 decapping mRNA 2 0.0188879
USP48 ubiquitin specific peptidase 48 0.0188788
NOL10 nucleolar protein 10 0.0188766
RNF43 ring finger protein 43 0.0188476
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.018842
CTSH cathepsin H 0.0188204
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0187851
PRPF38B pre-mRNA processing factor 38B 0.0187579
CTSB cathepsin B 0.0187422
ELP4 elongator acetyltransferase complex subunit 4 0.0187359
NXF1 nuclear RNA export factor 1 0.0187108
CCDC125 coiled-coil domain containing 125 0.0187077
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.018704
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0187033
DRC8 dynein regulatory complex subunit 8 0.0186938
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.0186904
STXBP3 syntaxin binding protein 3 0.0186892
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.0186832
LDLR low density lipoprotein receptor 0.0186721
THUMPD3 THUMP domain containing 3 0.0186402
CD44 CD44 molecule (Indian blood group) 0.0186315
XKR3 XK, Kell blood group complex subunit-related family, member 3 0.0186283
EEF2 eukaryotic translation elongation factor 2 0.018617
IL13RA1 interleukin 13 receptor, alpha 1 0.0185909
RIOK3 RIO kinase 3 0.0185704
CRTC3 CREB regulated transcription coactivator 3 0.0185387
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.0185328
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.0185273
KIF5B kinesin family member 5B 0.0185092
AKAP1 A kinase (PRKA) anchor protein 1 0.0185088
RPL23 ribosomal protein L23 0.0185057
ZNF282 zinc finger protein 282 0.0184944
ACO2 aconitase 2, mitochondrial 0.0184892
EMC7 ER membrane protein complex subunit 7 0.0184752
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 0.0184734
CAPN15 calpain 15 0.0183889
PRR11 proline rich 11 0.0183857
KIF4A kinesin family member 4A 0.0183814
TTC1 tetratricopeptide repeat domain 1 0.018324
TOR1AIP2 torsin A interacting protein 2 0.0182966
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.0182897
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0182776
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0182624
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.0182206
LONP2 lon peptidase 2, peroxisomal 0.0181567
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0181456
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0181297
PDHX pyruvate dehydrogenase complex, component X 0.0180999
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.0180689
ATOSA atos homolog A 0.0180555
ZFYVE28 zinc finger, FYVE domain containing 28 0.0180461
RBM39 RNA binding motif protein 39 0.01803
NCOA1 nuclear receptor coactivator 1 0.0180242
MGST3 microsomal glutathione S-transferase 3 0.0180053
TCF20 transcription factor 20 (AR1) 0.0179707
VDAC3 voltage-dependent anion channel 3 0.0179471
AOPEP aminopeptidase O (putative) 0.0179093
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0178453
LTAP1 lipid transport auxiliary protein 1 0.0178243
TUBA1C tubulin, alpha 1c 0.0177954
TBCE tubulin folding cofactor E 0.0177321
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.0177278
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0177267
EDF1 endothelial differentiation-related factor 1 0.0177037
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.017692
KDM3A lysine (K)-specific demethylase 3A 0.0176831
LARP1 La ribonucleoprotein domain family, member 1 0.0176294
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0176141
SCAF8 SR-related CTD-associated factor 8 0.0176102
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.0176033
CENPP centromere protein P 0.0175784
WWOX WW domain containing oxidoreductase 0.0175351
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0175185
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.0174675
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.0174298
SPRED2 sprouty-related, EVH1 domain containing 2 0.0174245
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.0173954
TSC22D2 TSC22 domain family, member 2 0.0173933
TM9SF2 transmembrane 9 superfamily member 2 0.0173824
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.0173542
SF3A3 splicing factor 3a, subunit 3, 60kDa 0.017317
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.0172972
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0172852
IPO9 importin 9 0.0172708
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.01727
DCLRE1C DNA cross-link repair 1C 0.0172662
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.0172477
ADNP activity-dependent neuroprotector homeobox 0.0171781
TJP2 tight junction protein 2 0.01717
PCDH9 protocadherin 9 0.0171505
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.017102
ETFDH electron-transferring-flavoprotein dehydrogenase 0.0170902
TMC6 transmembrane channel-like 6 0.0170482
CDC27 cell division cycle 27 0.0170469
TOX4 TOX high mobility group box family member 4 0.0170331
BLVRB biliverdin reductase B 0.0170275
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.0170233
EXOC6 exocyst complex component 6 0.0169607
TTF1 transcription termination factor, RNA polymerase I 0.0169081
TASOR2 transcription activation suppressor family member 2 0.0168742
METTL8 methyltransferase like 8 0.0168597
MRPS35 mitochondrial ribosomal protein S35 0.0168308
CARS1 cysteinyl-tRNA synthetase 1 0.0168077
ANXA1 annexin A1 0.0167917
DNASE1 deoxyribonuclease I 0.0167662
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 0.0167638
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.0167506
BAG4 BCL2-associated athanogene 4 0.0167305
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.016708
LYPLAL1 lysophospholipase-like 1 0.0166243
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.0166216
LMO2 LIM domain only 2 (rhombotin-like 1) 0.016605
HELLS helicase, lymphoid-specific 0.0165956
ATG10 autophagy related 10 0.0165875
GLB1 galactosidase, beta 1 0.016561
TTC21B tetratricopeptide repeat domain 21B 0.0165553
ZNF160 zinc finger protein 160 0.0165125
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.0164414
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0164375
FOXN2 forkhead box N2 0.0164322
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.0164077
DNM2 dynamin 2 0.0164058
NEMF nuclear export mediator factor 0.0164013
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.0163977
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0163795
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.0163484
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0163221
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0162881
ARLN allregulin 0.0162691
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.0162662
RPS24 ribosomal protein S24 0.0162381
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0162266
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0162149
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0162036
RPL18A ribosomal protein L18a 0.016173
LRRC4B leucine rich repeat containing 4B 0.0161585
RPS19 ribosomal protein S19 0.0161349
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.0161282
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0161209
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 0.0160953
TMEM135 transmembrane protein 135 0.016087
SPIRE1 spire-type actin nucleation factor 1 0.0160798
QSER1 glutamine and serine rich 1 0.0160559
VDAC1 voltage-dependent anion channel 1 0.0160415
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.0160378
RNF115 ring finger protein 115 0.0160332
SCAP SREBF chaperone 0.016016
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0160141
HEATR3 HEAT repeat containing 3 0.0159915
CNOT8 CCR4-NOT transcription complex, subunit 8 0.0159895
STX8 syntaxin 8 0.0159752
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.015974
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0159458
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0159371
ARHGAP4 Rho GTPase activating protein 4 0.0159255
C9ORF78 chromosome 9 open reading frame 78 0.0158901
PPP1R12C protein phosphatase 1, regulatory subunit 12C 0.015874
EPAS1 endothelial PAS domain protein 1 0.0158693

decreased expression

Symbol Name Standardized Value
ARL15 ADP-ribosylation factor-like 15 -0.119851
SRPK2 SRSF protein kinase 2 -0.0714412
NLRP1 NLR family, pyrin domain containing 1 -0.0700937
FBXL13 F-box and leucine-rich repeat protein 13 -0.0698893
JMJD1C jumonji domain containing 1C -0.0655552
GPC5 glypican 5 -0.0622817
ESYT2 extended synaptotagmin-like protein 2 -0.0596408
WASF2 WAS protein family, member 2 -0.0567872
NFIA nuclear factor I/A -0.0560358
RNASE3 ribonuclease, RNase A family, 3 -0.0549518
COPA coatomer protein complex, subunit alpha -0.0494535
ANO10 anoctamin 10 -0.048844
CREBBP CREB binding protein -0.0478066
MCAM melanoma cell adhesion molecule -0.0465229
TTC3 tetratricopeptide repeat domain 3 -0.0454896
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0442123
TENM1 teneurin transmembrane protein 1 -0.0431814
NF1 neurofibromin 1 -0.0428698
FGF13 fibroblast growth factor 13 -0.0414396
MAPK1 mitogen-activated protein kinase 1 -0.0413268
BMP2K BMP2 inducible kinase -0.0409127
GAB2 GRB2-associated binding protein 2 -0.0404184
ANK1 ankyrin 1, erythrocytic -0.0398523
SLTM SAFB-like, transcription modulator -0.0398423
PRKCB protein kinase C, beta -0.03976
TAOK1 TAO kinase 1 -0.0390726
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0381543
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0380991
SQLE squalene epoxidase -0.0380756
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0378527
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0374049
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.037075
TRIM24 tripartite motif containing 24 -0.0368996
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0367474
TGFB1 transforming growth factor, beta 1 -0.0366561
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0362861
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0362313
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0357735
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0357288
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0353845
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.0353044
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0352474
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0350706
MICU1 mitochondrial calcium uptake 1 -0.0349369
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.034582
PTPRJ protein tyrosine phosphatase, receptor type, J -0.03424
NCAM2 neural cell adhesion molecule 2 -0.0340678
RTN3 reticulon 3 -0.0337152
SMYD3 SET and MYND domain containing 3 -0.0335294
ENO1 enolase 1, (alpha) -0.0330878
RNF217 ring finger protein 217 -0.0330669
ANKRD17 ankyrin repeat domain 17 -0.0329654
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0329047
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0324052
FLNB filamin B, beta -0.0323236
TNPO1 transportin 1 -0.0322967
TNIK TRAF2 and NCK interacting kinase -0.0322914
AARS1 alanyl-tRNA synthetase 1 -0.0320898
VMP1 vacuole membrane protein 1 -0.031997
SETX senataxin -0.03199
ETV6 ets variant 6 -0.0319444
SETD2 SET domain containing 2 -0.0316274
UBE4B ubiquitination factor E4B -0.0314132
MEIS2 Meis homeobox 2 -0.0311849
SNX3 sorting nexin 3 -0.0311787
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0309119
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0308054
TPST2 tyrosylprotein sulfotransferase 2 -0.0308001
KIF2C kinesin family member 2C -0.0307211
PTBP3 polypyrimidine tract binding protein 3 -0.030433
GLMN glomulin, FKBP associated protein -0.0300423
SCLT1 sodium channel and clathrin linker 1 -0.0298662
PRELID2 PRELI domain containing 2 -0.0298438
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.029765
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0296693
ABHD3 abhydrolase domain containing 3 -0.0296096
TAOK3 TAO kinase 3 -0.0295299
MFSD11 major facilitator superfamily domain containing 11 -0.0294734
SSBP3 single stranded DNA binding protein 3 -0.0293834
ACTN1 actinin, alpha 1 -0.0293798
UBN1 ubinuclein 1 -0.0291012
VTA1 vesicle (multivesicular body) trafficking 1 -0.028975
SAMD4A sterile alpha motif domain containing 4A -0.0289312
RB1 retinoblastoma 1 -0.0287514
CDC14A cell division cycle 14A -0.0284074
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0281978
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0281561
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0280833
CDK6 cyclin-dependent kinase 6 -0.0280793
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0279318
MIA3 melanoma inhibitory activity family, member 3 -0.0279165
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0278914
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0278535
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0277874
SUSD1 sushi domain containing 1 -0.0277606
RUNX1 runt-related transcription factor 1 -0.0277587
YEATS2 YEATS domain containing 2 -0.0276472
KDM2A lysine (K)-specific demethylase 2A -0.0275897
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0275841
PDLIM5 PDZ and LIM domain 5 -0.0275669
LIN28B lin-28 homolog B (C. elegans) -0.0275379
DOCK8 dedicator of cytokinesis 8 -0.0274157
ELOVL6 ELOVL fatty acid elongase 6 -0.0273995
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -0.027343
SPATS2 spermatogenesis associated, serine-rich 2 -0.0273317
JAK1 Janus kinase 1 -0.0272989
LARS1 leucyl-tRNA synthetase 1 -0.0271859
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.0271384
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0270998
INSIG1 insulin induced gene 1 -0.027052
PLCL1 phospholipase C-like 1 -0.0269493
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -0.0268779
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -0.0267639
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0266374
KSR1 kinase suppressor of ras 1 -0.0266156
UIMC1 ubiquitin interaction motif containing 1 -0.0265397
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 -0.0261298
MACO1 macoilin 1 -0.0261246
BCR breakpoint cluster region -0.026027
MARCHF3 membrane associated ring-CH-type finger 3 -0.0260182
TPM3 tropomyosin 3 -0.0259875
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -0.025935
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0259329
STK4 serine/threonine kinase 4 -0.0259057
SMAP2 small ArfGAP2 -0.0257595
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0257293
USP32 ubiquitin specific peptidase 32 -0.02567
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0256596
CSMD1 CUB and Sushi multiple domains 1 -0.0255627
NCOA3 nuclear receptor coactivator 3 -0.025562
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0255419
SCAI suppressor of cancer cell invasion -0.0255212
NUP93 nucleoporin 93kDa -0.0253755
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0252631
GOLGA4 golgin A4 -0.0251943
CDK17 cyclin-dependent kinase 17 -0.0249897
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0249465
SSH2 slingshot protein phosphatase 2 -0.0248602
PEX6 peroxisomal biogenesis factor 6 -0.024838
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -0.0248375
CAMKMT calmodulin-lysine N-methyltransferase -0.0247835
DSTYK dual serine/threonine and tyrosine protein kinase -0.0247624
KHSRP KH-type splicing regulatory protein -0.024734
SSR1 signal sequence receptor, alpha -0.0247325
KNTC1 kinetochore associated 1 -0.0247105
NAP1L1 nucleosome assembly protein 1-like 1 -0.0246716
EIF4B eukaryotic translation initiation factor 4B -0.0246086
RPL19 ribosomal protein L19 -0.0245931
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0245446
MYO1D myosin ID -0.0245389
CAPRIN1 cell cycle associated protein 1 -0.0242915
MEF2C myocyte enhancer factor 2C -0.0242435
WDTC1 WD and tetratricopeptide repeats 1 -0.0241587
KPNB1 karyopherin (importin) beta 1 -0.0239808
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0238857
AAK1 AP2 associated kinase 1 -0.0238328
INVS inversin -0.0237541
CALR calreticulin -0.0237413
TRAPPC9 trafficking protein particle complex 9 -0.023694
MCU mitochondrial calcium uniporter -0.0236269
UBE2K ubiquitin-conjugating enzyme E2K -0.0236227
FBXL20 F-box and leucine-rich repeat protein 20 -0.0236061
MRPS18B mitochondrial ribosomal protein S18B -0.0236031
SEC31A SEC31 homolog A (S. cerevisiae) -0.0235762
CDC42SE2 CDC42 small effector 2 -0.023555
TBC1D5 TBC1 domain family, member 5 -0.0235252
RORA RAR-related orphan receptor A -0.0235038
DENND4A DENN/MADD domain containing 4A -0.0234967
TBCK TBC1 domain containing kinase -0.0234772
TAC4 tachykinin 4 (hemokinin) -0.0234539
ADGRV1 adhesion G protein-coupled receptor V1 -0.0234431
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0234101
TNPO2 transportin 2 -0.0233636
LMTK2 lemur tyrosine kinase 2 -0.0233577
LCORL ligand dependent nuclear receptor corepressor-like -0.0232768
WDPCP WD repeat containing planar cell polarity effector -0.0231908
LIN9 lin-9 DREAM MuvB core complex component -0.0231601
SUMF1 sulfatase modifying factor 1 -0.0230724
RSL24D1 ribosomal L24 domain containing 1 -0.0230556
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.0230211
RBM19 RNA binding motif protein 19 -0.0229927
NIBAN1 niban apoptosis regulator 1 -0.0229481
SIL1 SIL1 nucleotide exchange factor -0.0229477
CFAP161 cilia and flagella associated protein 161 -0.0228544
MMS22L MMS22-like, DNA repair protein -0.022841
CFAP20DC CFAP20 domain containing -0.0227819
GUSB glucuronidase, beta -0.0227575
SPOP speckle-type POZ protein -0.0227352
STK24 serine/threonine kinase 24 -0.0227233
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0226456
ACACA acetyl-CoA carboxylase alpha -0.022638
RPL35 ribosomal protein L35 -0.0226358
MYO9A myosin IXA -0.0226167
SSB Sjogren syndrome antigen B (autoantigen La) -0.0226128
SMIM44 small integral membrane protein 44 -0.0225873
SZRD1 SUZ RNA binding domain containing 1 -0.0224279
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0222129
UBE2H ubiquitin-conjugating enzyme E2H -0.0220407
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0219927
UBP1 upstream binding protein 1 (LBP-1a) -0.0219749
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0218945
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0218735
PDCD6IP programmed cell death 6 interacting protein -0.0218538
MAML3 mastermind-like 3 (Drosophila) -0.0218409
EPB41 erythrocyte membrane protein band 4.1 -0.0218287
FBXO11 F-box protein 11 -0.0218069
TOP1 topoisomerase (DNA) I -0.0216763
RPS12 ribosomal protein S12 -0.0216744
BRCA1 breast cancer 1, early onset -0.0216435
RHBDD2 rhomboid domain containing 2 -0.0216187
MFSD12 major facilitator superfamily domain containing 12 -0.0216165
GGNBP2 gametogenetin binding protein 2 -0.0215434
ZMYM5 zinc finger, MYM-type 5 -0.0215403
DMTF1 cyclin D binding myb-like transcription factor 1 -0.0215363
BIRC5 baculoviral IAP repeat containing 5 -0.0214968
TRAK1 trafficking protein, kinesin binding 1 -0.0214919
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0214398
VEPH1 ventricular zone expressed PH domain-containing 1 -0.0213621
CCNI cyclin I -0.0212957
FAM135A family with sequence similarity 135, member A -0.0212935
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.0212863
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0212683
PTRH2 peptidyl-tRNA hydrolase 2 -0.021252
MTMR3 myotubularin related protein 3 -0.021208
TMED3 transmembrane emp24 protein transport domain containing 3 -0.0211838
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -0.0211549
SKIL SKI-like proto-oncogene -0.021139
CAPN2 calpain 2, (m/II) large subunit -0.0211265
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0210159
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0209806
PHKB phosphorylase kinase, beta -0.0209454
NCALD neurocalcin delta -0.02088
FBXO28 F-box protein 28 -0.0208486
TNRC6B trinucleotide repeat containing 6B -0.0208478
NSUN4 NOP2/Sun domain family, member 4 -0.0208396
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0208185
FOXJ3 forkhead box J3 -0.0207047
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0206809
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta -0.0206505
RHOA ras homolog family member A -0.0205775
LCLAT1 lysocardiolipin acyltransferase 1 -0.0205375
CADM2 cell adhesion molecule 2 -0.0205253
MYEOV myeloma overexpressed -0.0205017
RNF169 ring finger protein 169 -0.0204897
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0204337
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0203685
SINHCAF SIN3-HDAC complex associated factor -0.0203396
EMC3 ER membrane protein complex subunit 3 -0.0202829
KIDINS220 kinase D-interacting substrate, 220kDa -0.0202107
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -0.0201638
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.020155
UBXN7 UBX domain protein 7 -0.0201267
TPP2 tripeptidyl peptidase II -0.0201221
USO1 USO1 vesicle transport factor -0.0200982
PKM pyruvate kinase, muscle -0.0200843
KIF23 kinesin family member 23 -0.0199859
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0199267
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0199227
PXDN peroxidasin -0.0199213
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) -0.01992
DIAPH3 diaphanous-related formin 3 -0.0198882
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0198757
PKP4 plakophilin 4 -0.0198729
MLH1 mutL homolog 1 -0.0198308
SRBD1 S1 RNA binding domain 1 -0.0198053
KIAA0319L KIAA0319-like -0.0197385
COPB1 coatomer protein complex, subunit beta 1 -0.0197168
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0197161
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0197134
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -0.0196897
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0196841
ALDOC aldolase C, fructose-bisphosphate -0.019662
FLOT2 flotillin 2 -0.0196371
EIF1 eukaryotic translation initiation factor 1 -0.0196107
UNC13D unc-13 homolog D (C. elegans) -0.0195975
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0195594
DEAF1 DEAF1 transcription factor -0.0194305
RBL1 retinoblastoma-like 1 -0.0193926
ZNF611 zinc finger protein 611 -0.0193884
TRIM56 tripartite motif containing 56 -0.0193713
SETD5 SET domain containing 5 -0.0193249
KMT5B lysine methyltransferase 5B -0.019318
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -0.0193173
CD2AP CD2-associated protein -0.0193143
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.0192976
SENP7 SUMO1/sentrin specific peptidase 7 -0.0192535
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.0192456
SYNJ2 synaptojanin 2 -0.0192204
C19ORF25 chromosome 19 open reading frame 25 -0.0192136
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0191576
MRPL13 mitochondrial ribosomal protein L13 -0.019144
AMPD3 adenosine monophosphate deaminase 3 -0.0191283
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0190731
FNBP4 formin binding protein 4 -0.0190437
SLC35F5 solute carrier family 35, member F5 -0.0190243
DHRS7B dehydrogenase/reductase (SDR family) member 7B -0.019023
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0189875
GOLGA8A golgin A8 family, member A -0.0189806
AHNAK AHNAK nucleoprotein -0.0189637
DPP8 dipeptidyl-peptidase 8 -0.018959
SON SON DNA binding protein -0.0189316
H2BC15 H2B clustered histone 15 -0.018851
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -0.0188448
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0188206
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0187786
ESRRA estrogen-related receptor alpha -0.0187761
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.018719
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0186739
STIP1 stress-induced phosphoprotein 1 -0.0185551
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0185129
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0185041
VWDE von Willebrand factor D and EGF domains -0.018478
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -0.0184644
DCTN4 dynactin 4 (p62) -0.0184269
TGOLN2 trans-golgi network protein 2 -0.018402
RDX radixin -0.0183857
APTX aprataxin -0.0183482
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -0.0182356
RPL28 ribosomal protein L28 -0.0182138
PRKD2 protein kinase D2 -0.018205
RAD18 RAD18 E3 ubiquitin protein ligase -0.0181651
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0181533
RNF157 ring finger protein 157 -0.0181409
FAM168B family with sequence similarity 168, member B -0.0180776
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0180735
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0179839
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0179802
STAU1 staufen double-stranded RNA binding protein 1 -0.0179702
SERF2 small EDRK-rich factor 2 -0.0179494
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -0.0179492
RUFY2 RUN and FYVE domain containing 2 -0.0179281
CHD8 chromodomain helicase DNA binding protein 8 -0.0179166
CA8 carbonic anhydrase VIII -0.0179097
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -0.0179087
SLC31A1 solute carrier family 31 (copper transporter), member 1 -0.0178633
PBK PDZ binding kinase -0.017829
ZNF217 zinc finger protein 217 -0.0178286
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -0.0178068
CALCOCO2 calcium binding and coiled-coil domain 2 -0.0177953
ZNF292 zinc finger protein 292 -0.0177484
SELENOF selenoprotein F -0.0176681
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0176403
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0176172
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.0175955
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0175815
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -0.0175758
TSG101 tumor susceptibility 101 -0.0175628
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0175529
MRPS16 mitochondrial ribosomal protein S16 -0.0174833
MAP7D1 MAP7 domain containing 1 -0.0174776
ERCC8 excision repair cross-complementation group 8 -0.017466
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.017424
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0174229
FOXM1 forkhead box M1 -0.0173603
PHF3 PHD finger protein 3 -0.017359
TUBB4B tubulin, beta 4B class IVb -0.0173409
ZNF367 zinc finger protein 367 -0.0173275
SMAD3 SMAD family member 3 -0.0173241
GLCE glucuronic acid epimerase -0.0173038
PHF21A PHD finger protein 21A -0.0173038
RPS25 ribosomal protein S25 -0.017284
NCOA7 nuclear receptor coactivator 7 -0.0172588
LCOR ligand dependent nuclear receptor corepressor -0.0172501
DOCK11 dedicator of cytokinesis 11 -0.0172182
CDK19 cyclin-dependent kinase 19 -0.0171723
HSPB11 heat shock protein family B (small), member 11 -0.0171551
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -0.0171547
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.0171517
PHTF2 putative homeodomain transcription factor 2 -0.0171282
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0171245
MPZ myelin protein zero -0.0171092
WDR27 WD repeat domain 27 -0.0170318
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0170267
DEK DEK proto-oncogene -0.0170262
CFH complement factor H -0.0170235
GDNF glial cell derived neurotrophic factor -0.0170225
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.016998
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.0169844
H2BC8 H2B clustered histone 8 -0.0169284
FCHSD2 FCH and double SH3 domains 2 -0.0169233
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -0.0169
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0168981
DENND5A DENN/MADD domain containing 5A -0.0168934
CSDE1 cold shock domain containing E1, RNA-binding -0.0168919
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0168863
GEN1 GEN1 Holliday junction 5' flap endonuclease -0.0168853
FDPS farnesyl diphosphate synthase -0.0168765
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0168754
MIPOL1 mirror-image polydactyly 1 -0.0168549
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0168078
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0168053
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0167543
WWC2 WW and C2 domain containing 2 -0.0166971
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0166358
NME7 NME/NM23 family member 7 -0.0166351
WAC WW domain containing adaptor with coiled-coil -0.0165557
FGGY FGGY carbohydrate kinase domain containing -0.016535
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -0.0164593
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 -0.0164517
PRPF8 pre-mRNA processing factor 8 -0.0163228
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.016303
THSD4 thrombospondin, type I, domain containing 4 -0.0162765
STX2 syntaxin 2 -0.016231
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.0162099
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0162071
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.0161975
LUZP1 leucine zipper protein 1 -0.0161948
CCNY cyclin Y -0.0161946
CERS6 ceramide synthase 6 -0.0161794
TXNIP thioredoxin interacting protein -0.0161743
OSBPL6 oxysterol binding protein-like 6 -0.0161346
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0161157
MAP2K5 mitogen-activated protein kinase kinase 5 -0.0160992
RAD23B RAD23 homolog B (S. cerevisiae) -0.016085
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0160823
C16ORF95 chromosome 16 open reading frame 95 -0.0160793
MSN moesin -0.0160261
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -0.0160171
CSPP1 centrosome and spindle pole associated protein 1 -0.0160114
MRE11 MRE11 homolog, double strand break repair nuclease -0.0160079
RNF145 ring finger protein 145 -0.0160009
TTLL3 tubulin tyrosine ligase-like family member 3 -0.0159904
SCAPER S-phase cyclin A-associated protein in the ER -0.0159631
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -0.0159519
ANAPC11 anaphase promoting complex subunit 11 -0.015946
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0159416
PNISR PNN-interacting serine/arginine-rich protein -0.0159372
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.0158547
IFT88 intraflagellar transport 88 -0.0158255
AHDC1 AT hook, DNA binding motif, containing 1 -0.0158236
TASOR transcription activation suppressor -0.0158198
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0157993
FRYL FRY-like -0.015785
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0157646
RNF114 ring finger protein 114 -0.0157475
WDFY3 WD repeat and FYVE domain containing 3 -0.0157424
RAP1B RAP1B, member of RAS oncogene family -0.0157367
METAP1 methionyl aminopeptidase 1 -0.0157213
DBF4 DBF4 zinc finger -0.0156877
RANBP10 RAN binding protein 10 -0.0156583
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0156561
C11ORF58 chromosome 11 open reading frame 58 -0.0156537
TM9SF3 transmembrane 9 superfamily member 3 -0.0156416
PPP1R21 protein phosphatase 1, regulatory subunit 21 -0.0155942
RHOT1 ras homolog family member T1 -0.0155695
SERP1 stress-associated endoplasmic reticulum protein 1 -0.0155666
CBFB core-binding factor, beta subunit -0.0155558
NEK7 NIMA-related kinase 7 -0.0155343
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -0.0155104
EI24 etoposide induced 2.4 -0.0154992
GNPAT glyceronephosphate O-acyltransferase -0.0154987
MIS18BP1 MIS18 binding protein 1 -0.015491
TMEM161B transmembrane protein 161B -0.0154706
COP1 COP1 E3 ubiquitin ligase -0.015464
GMEB1 glucocorticoid modulatory element binding protein 1 -0.0154338
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0154147
CCDC137 coiled-coil domain containing 137 -0.0153878
FAM178B family with sequence similarity 178, member B -0.0153846
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.0153827
CSNK1D casein kinase 1, delta -0.0153622
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -0.0153586
SBF2 SET binding factor 2 -0.0153462
TMEM161A transmembrane protein 161A -0.0152945
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0152625
AXIN1 axin 1 -0.0152435
KRIT1 KRIT1, ankyrin repeat containing -0.0152327
DOCK7 dedicator of cytokinesis 7 -0.0151644
UVRAG UV radiation resistance associated -0.0151522
HOOK3 hook microtubule-tethering protein 3 -0.0151371
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.0151045
MLXIP MLX interacting protein -0.0151014
AGO2 argonaute RISC catalytic component 2 -0.0150989
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -0.0150822
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0150789
SEC63 SEC63 homolog (S. cerevisiae) -0.0150598
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -0.0150529
BCL2L12 BCL2-like 12 (proline rich) -0.0150524
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0150518
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.015037
STIM2 stromal interaction molecule 2 -0.015028
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.0150171
TBC1D32 TBC1 domain family, member 32 -0.0150171
CDCA8 cell division cycle associated 8 -0.0149723
SLMAP sarcolemma associated protein -0.014952
FAM13B family with sequence similarity 13, member B -0.0149516
NOP58 NOP58 ribonucleoprotein -0.0149192
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0149035
ECE1 endothelin converting enzyme 1 -0.0148972
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0148846
DCAF10 DDB1 and CUL4 associated factor 10 -0.0148797
APLF aprataxin and PNKP like factor -0.0148674
CHD1 chromodomain helicase DNA binding protein 1 -0.0148626
ATL3 atlastin GTPase 3 -0.0148507
DNAAF9 dynein axonemal assembly factor 9 -0.0148387
ELP2 elongator acetyltransferase complex subunit 2 -0.0148387
FUBP1 far upstream element (FUSE) binding protein 1 -0.0148324
SLC25A42 solute carrier family 25, member 42 -0.0148285
ALMS1 Alstrom syndrome protein 1 -0.0148073
NDE1 nudE neurodevelopment protein 1 -0.014786
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.0147569