K562_GSK J1_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 10µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK J1_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
FLNA filamin A, alpha 0.115198
HBG1 hemoglobin, gamma A 0.0975381
MUSK muscle, skeletal, receptor tyrosine kinase 0.0954485
ZNF609 zinc finger protein 609 0.0771553
MAML2 mastermind-like 2 (Drosophila) 0.0676562
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0650173
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0644302
CALN1 calneuron 1 0.0601792
ZMYM4 zinc finger, MYM-type 4 0.0590578
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.0590273
PHIP pleckstrin homology domain interacting protein 0.0582097
PRRC2C proline-rich coiled-coil 2C 0.0579765
LARP1 La ribonucleoprotein domain family, member 1 0.0560439
FAM13A family with sequence similarity 13, member A 0.0555565
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0551446
PUM1 pumilio RNA-binding family member 1 0.0511913
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0511545
ANKRD11 ankyrin repeat domain 11 0.0500779
RIPOR3 RIPOR family member 3 0.0499737
LDLR low density lipoprotein receptor 0.0497827
RPL4 ribosomal protein L4 0.0490448
SNX9 sorting nexin 9 0.0486918
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0464746
SETD2 SET domain containing 2 0.0462479
CCNI cyclin I 0.0462254
AKAP9 A kinase (PRKA) anchor protein 9 0.0460067
UNC13D unc-13 homolog D (C. elegans) 0.0456518
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0454515
NFIA nuclear factor I/A 0.0439329
SRSF10 serine/arginine-rich splicing factor 10 0.0435708
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.042926
FBXL13 F-box and leucine-rich repeat protein 13 0.0411896
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.0403663
ARHGAP24 Rho GTPase activating protein 24 0.040348
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.040176
PTPN7 protein tyrosine phosphatase, non-receptor type 7 0.0396565
BCAS3 breast carcinoma amplified sequence 3 0.039412
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0390673
JMJD1C jumonji domain containing 1C 0.0388987
RPLP1 ribosomal protein, large, P1 0.0387501
CALU calumenin 0.0387168
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0382049
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0378594
SNX29 sorting nexin 29 0.0377672
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0375082
FRYL FRY-like 0.0372125
NOP58 NOP58 ribonucleoprotein 0.0370225
FTL ferritin, light polypeptide 0.036965
ANKRD17 ankyrin repeat domain 17 0.0369599
SFPQ splicing factor proline/glutamine-rich 0.0366254
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0365128
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.036307
RAB31 RAB31, member RAS oncogene family 0.0362531
MACROH2A1 macroH2A.1 histone 0.0358877
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0357375
CD2AP CD2-associated protein 0.0356946
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0353066
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.034942
OLA1 Obg-like ATPase 1 0.0347299
ENO1 enolase 1, (alpha) 0.033502
PLEC plectin 0.0334526
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0333499
ZDHHC14 zinc finger, DHHC-type containing 14 0.0333466
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0329737
RANBP9 RAN binding protein 9 0.0329557
HIP1 huntingtin interacting protein 1 0.0327716
WDR33 WD repeat domain 33 0.0324943
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.032324
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0322332
PTK2 protein tyrosine kinase 2 0.0322257
TUBA1B tubulin, alpha 1b 0.0322165
TMC6 transmembrane channel-like 6 0.0317318
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0314425
LIN54 lin-54 DREAM MuvB core complex component 0.031199
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.0311859
MFGE8 milk fat globule-EGF factor 8 protein 0.0311557
ACVR1 activin A receptor, type I 0.0310012
AFDN afadin, adherens junction formation factor 0.0309358
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.0306643
SQSTM1 sequestosome 1 0.0305928
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0305838
TET1 tet methylcytosine dioxygenase 1 0.0304372
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0303938
TGFB1 transforming growth factor, beta 1 0.0302867
TMOD3 tropomodulin 3 (ubiquitous) 0.0301187
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0300479
COG5 component of oligomeric golgi complex 5 0.0298891
TPI1 triosephosphate isomerase 1 0.0298144
TRRAP transformation/transcription domain-associated protein 0.0297872
ETV1 ets variant 1 0.0297707
LATS1 large tumor suppressor kinase 1 0.029546
DENND1A DENN/MADD domain containing 1A 0.0294998
SLC43A3 solute carrier family 43, member 3 0.0294323
KIF13A kinesin family member 13A 0.0294183
TNIK TRAF2 and NCK interacting kinase 0.0293891
ZMYND8 zinc finger, MYND-type containing 8 0.0293752
CLIC1 chloride intracellular channel 1 0.0293361
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.0293336
SRRM2 serine/arginine repetitive matrix 2 0.0292296
TEX2 testis expressed 2 0.0289239
E2F3 E2F transcription factor 3 0.0288593
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 0.0287873
UBE4B ubiquitination factor E4B 0.0287211
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.028697
AGO2 argonaute RISC catalytic component 2 0.0286821
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.0285052
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0284889
PLIN3 perilipin 3 0.0282418
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0281728
FDPS farnesyl diphosphate synthase 0.0280803
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.0280604
SIMC1 SUMO-interacting motifs containing 1 0.0279849
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0279641
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0278086
EEF2 eukaryotic translation elongation factor 2 0.0276357
CCDC91 coiled-coil domain containing 91 0.0276191
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.0275487
AK1 adenylate kinase 1 0.0275077
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.027369
SRSF11 serine/arginine-rich splicing factor 11 0.0272881
HOOK3 hook microtubule-tethering protein 3 0.0272706
TTC28 tetratricopeptide repeat domain 28 0.0270799
TRIM37 tripartite motif containing 37 0.0270701
H2AC6 H2A clustered histone 6 0.0269411
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0268182
TMEM41A transmembrane protein 41A 0.0266681
MARCHF6 membrane associated ring-CH-type finger 6 0.0266563
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 0.0266236
BIRC6 baculoviral IAP repeat containing 6 0.0266101
FANCL Fanconi anemia, complementation group L 0.0266035
UBA2 ubiquitin-like modifier activating enzyme 2 0.0265849
AHNAK AHNAK nucleoprotein 0.0264396
SETD5 SET domain containing 5 0.0264279
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.0264107
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0262549
UNK unkempt family zinc finger 0.0262109
CST3 cystatin C 0.0261641
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.026141
CR1L complement component (3b/4b) receptor 1-like 0.0260768
FAM222B family with sequence similarity 222, member B 0.0260605
SESN2 sestrin 2 0.026005
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0259911
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.025916
LIN9 lin-9 DREAM MuvB core complex component 0.0258635
URM1 ubiquitin related modifier 1 0.0257832
COX5B cytochrome c oxidase subunit Vb 0.025769
NCOA3 nuclear receptor coactivator 3 0.025715
RAB10 RAB10, member RAS oncogene family 0.0257032
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.0256835
TGOLN2 trans-golgi network protein 2 0.0255538
SRPK1 SRSF protein kinase 1 0.0254046
CD63 CD63 molecule 0.0253614
N4BP2 NEDD4 binding protein 2 0.0253469
MCU mitochondrial calcium uniporter 0.0253026
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.0252271
MED23 mediator complex subunit 23 0.0252183
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.0251204
COG7 component of oligomeric golgi complex 7 0.025108
BTNL9 butyrophilin-like 9 0.0250436
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0249529
ATM ATM serine/threonine kinase 0.0249187
EFCAB10 EF-hand calcium binding domain 10 0.0248375
SLC10A7 solute carrier family 10, member 7 0.0248321
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.024822
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0247935
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0247721
RAB1A RAB1A, member RAS oncogene family 0.0247124
FAM174B family with sequence similarity 174, member B 0.0246673
UVRAG UV radiation resistance associated 0.0245902
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0245846
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0244929
MCM4 minichromosome maintenance complex component 4 0.0244889
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0244786
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0244745
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 0.0244727
ZBTB38 zinc finger and BTB domain containing 38 0.0243851
KMT5B lysine methyltransferase 5B 0.0243532
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0243302
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0243235
MAST2 microtubule associated serine/threonine kinase 2 0.0242344
ATOSA atos homolog A 0.0242096
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.02419
IQSEC2 IQ motif and Sec7 domain 2 0.0241161
VARS1 valyl-tRNA synthetase 1 0.0239069
INVS inversin 0.0238697
DGLUCY D-glutamate cyclase 0.0238656
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0238558
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0238289
TCF20 transcription factor 20 (AR1) 0.0237864
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0236734
RNF217 ring finger protein 217 0.0235813
TIMP1 TIMP metallopeptidase inhibitor 1 0.0235613
FXN frataxin 0.0235468
EIF3K eukaryotic translation initiation factor 3, subunit K 0.023521
CEP57L1 centrosomal protein 57kDa-like 1 0.0234531
TLN1 talin 1 0.0233698
LAPTM4B lysosomal protein transmembrane 4 beta 0.0233223
KCTD20 potassium channel tetramerization domain containing 20 0.0232762
ITGAV integrin, alpha V 0.0232549
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.0232427
RAD23B RAD23 homolog B (S. cerevisiae) 0.0232051
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0231969
SP3 Sp3 transcription factor 0.0231534
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0231157
ELP2 elongator acetyltransferase complex subunit 2 0.0231096
ANTXR2 anthrax toxin receptor 2 0.0231017
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.0230737
VWDE von Willebrand factor D and EGF domains 0.0230515
RAI14 retinoic acid induced 14 0.0230106
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0229698
WDR44 WD repeat domain 44 0.0228592
BLVRB biliverdin reductase B 0.0228424
ZNF800 zinc finger protein 800 0.0228386
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0227664
SPNS1 spinster homolog 1 (Drosophila) 0.0226804
VRK1 vaccinia related kinase 1 0.0225891
MADD MAP-kinase activating death domain 0.0225149
RUNX1 runt-related transcription factor 1 0.022491
STRN striatin, calmodulin binding protein 0.022433
KPNB1 karyopherin (importin) beta 1 0.02237
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.022331
USP15 ubiquitin specific peptidase 15 0.0223109
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0222883
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.0222875
BRCA1 breast cancer 1, early onset 0.0222831
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 0.0222635
MCM3AP minichromosome maintenance complex component 3 associated protein 0.0222414
EIF3L eukaryotic translation initiation factor 3, subunit L 0.0222376
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.0222193
AHI1 Abelson helper integration site 1 0.0221982
KLHDC10 kelch domain containing 10 0.0221828
SASH1 SAM and SH3 domain containing 1 0.022134
MACO1 macoilin 1 0.0221196
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0220897
PHF19 PHD finger protein 19 0.0220708
RPTOR regulatory associated protein of MTOR, complex 1 0.0220255
ECI1 enoyl-CoA delta isomerase 1 0.0219141
HELZ helicase with zinc finger 0.0218843
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0218208
LIMK2 LIM domain kinase 2 0.0217973
WAC WW domain containing adaptor with coiled-coil 0.0217689
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0217041
RPS5 ribosomal protein S5 0.0216883
FYB1 FYN binding protein 1 0.0216513
OXCT1 3-oxoacid CoA transferase 1 0.021651
NIBAN1 niban apoptosis regulator 1 0.0215316
HSPB1 heat shock 27kDa protein 1 0.0214703
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0214633
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.0213728
C1RL complement component 1, r subcomponent-like 0.0213406
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0213363
LMNA lamin A/C 0.021239
PRR11 proline rich 11 0.0212215
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0211803
ACOD1 aconitate decarboxylase 1 0.0211777
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.0210314
CEBPZOS CEBPZ opposite strand 0.021014
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.0209986
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.020967
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0209532
CENPK centromere protein K 0.020842
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.0208287
ABI2 abl-interactor 2 0.0207967
PHF20 PHD finger protein 20 0.0207658
CARS1 cysteinyl-tRNA synthetase 1 0.020722
GSK3B glycogen synthase kinase 3 beta 0.0207072
DCAF7 DDB1 and CUL4 associated factor 7 0.0206146
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0205942
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0205694
QSER1 glutamine and serine rich 1 0.0205138
SPIRE1 spire-type actin nucleation factor 1 0.0204674
AFG2A AFG2 AAA ATPase homolog A 0.0204502
WDR73 WD repeat domain 73 0.0204379
TP53BP1 tumor protein p53 binding protein 1 0.0204038
GNAS GNAS complex locus 0.0203559
XPR1 xenotropic and polytropic retrovirus receptor 1 0.020354
CLYBL citrate lyase beta like 0.0202643
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0202525
KLHDC3 kelch domain containing 3 0.0202032
TSPAN14 tetraspanin 14 0.0201776
CREB1 cAMP responsive element binding protein 1 0.0201713
SOS2 son of sevenless homolog 2 (Drosophila) 0.0201253
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.0200784
IFRD1 interferon-related developmental regulator 1 0.0200036
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0199914
PRICKLE1 prickle homolog 1 (Drosophila) 0.0199552
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 0.0199276
PLA2G12A phospholipase A2, group XIIA 0.0199236
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0199148
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0198954
DPY19L1 dpy-19-like 1 (C. elegans) 0.0198952
STK24 serine/threonine kinase 24 0.0198671
RBM20 RNA binding motif protein 20 0.0198655
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0198473
TFF1 trefoil factor 1 0.0198154
CRY2 cryptochrome circadian clock 2 0.019771
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0197652
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.0197452
SIK2 salt-inducible kinase 2 0.0197314
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0197135
CXXC5 CXXC finger protein 5 0.0197086
FOXP1 forkhead box P1 0.0196954
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 0.019672
TMEM19 transmembrane protein 19 0.019665
LMAN1 lectin, mannose-binding, 1 0.0196544
SEPTIN6 septin 6 0.0196465
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.0196104
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.0196062
METTL15 methyltransferase like 15 0.0195652
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0195067
TTL tubulin tyrosine ligase 0.0194637
PTGES2 prostaglandin E synthase 2 0.0194581
CLSTN1 calsyntenin 1 0.0194552
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0194481
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.0194375
KCMF1 potassium channel modulatory factor 1 0.0194161
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 0.0194032
CORO1C coronin, actin binding protein, 1C 0.0194027
NSRP1 nuclear speckle splicing regulatory protein 1 0.0193586
RHOBTB3 Rho-related BTB domain containing 3 0.0193503
NCAPG2 non-SMC condensin II complex, subunit G2 0.0193163
NUP43 nucleoporin 43kDa 0.0192949
TFR2 transferrin receptor 2 0.0192823
GFM2 G elongation factor, mitochondrial 2 0.0191784
NUP153 nucleoporin 153kDa 0.0191483
TDG thymine-DNA glycosylase 0.0191404
SET SET nuclear proto-oncogene 0.0191216
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0191002
THSD4 thrombospondin, type I, domain containing 4 0.0190862
CHD7 chromodomain helicase DNA binding protein 7 0.0190234
NAV1 neuron navigator 1 0.0189653
F2R coagulation factor II (thrombin) receptor 0.0189156
ELF4 E74-like factor 4 (ets domain transcription factor) 0.0189064
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.018906
PPHLN1 periphilin 1 0.0188788
FLNB filamin B, beta 0.0188576
HLA-E major histocompatibility complex, class I, E 0.0188576
ARHGAP15 Rho GTPase activating protein 15 0.0188476
RAB27A RAB27A, member RAS oncogene family 0.0188228
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0187814
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0187749
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0186995
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.0186789
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0186236
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0186108
ZNF100 zinc finger protein 100 0.018601
WDR4 WD repeat domain 4 0.0185764
RAP1B RAP1B, member of RAS oncogene family 0.0185745
EGFL7 EGF-like-domain, multiple 7 0.0185374
CUX1 cut-like homeobox 1 0.0184847
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.0184669
SNRPA small nuclear ribonucleoprotein polypeptide A 0.018464
ZC3H7B zinc finger CCCH-type containing 7B 0.0184426
PRKD3 protein kinase D3 0.0184172
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.018392
GNS glucosamine (N-acetyl)-6-sulfatase 0.0183897
CNTRL centriolin 0.0183474
E2F7 E2F transcription factor 7 0.0183305
DMTF1 cyclin D binding myb-like transcription factor 1 0.0183085
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0182945
ADSS2 adenylosuccinate synthase 2 0.0182751
ADAM17 ADAM metallopeptidase domain 17 0.0182745
PRR16 proline rich 16 0.018268
CRY1 cryptochrome circadian clock 1 0.0182598
TOP2B topoisomerase (DNA) II beta 180kDa 0.0181965
SMC4 structural maintenance of chromosomes 4 0.0181959
GFM1 G elongation factor, mitochondrial 1 0.0181781
SELENOI selenoprotein I 0.0181751
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 0.01815
SYMPK symplekin 0.0181112
SFXN1 sideroflexin 1 0.0180977
DPP9 dipeptidyl-peptidase 9 0.0180975
CSNK1A1 casein kinase 1, alpha 1 0.01807
SNX13 sorting nexin 13 0.0180649
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0180247
SAMD4B sterile alpha motif domain containing 4B 0.018008
SIL1 SIL1 nucleotide exchange factor 0.0179938
SERINC5 serine incorporator 5 0.0179699
CCDC137 coiled-coil domain containing 137 0.0179614
WNK1 WNK lysine deficient protein kinase 1 0.017931
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0179292
ECI2 enoyl-CoA delta isomerase 2 0.0179257
LDHA lactate dehydrogenase A 0.0179142
HMBS hydroxymethylbilane synthase 0.0178924
SRPK2 SRSF protein kinase 2 0.0178921
KIF2A kinesin heavy chain member 2A 0.0178719
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.0178505
NEMF nuclear export mediator factor 0.0178453
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.0178402
CHID1 chitinase domain containing 1 0.0178335
FBXO33 F-box protein 33 0.0177879
CAPN2 calpain 2, (m/II) large subunit 0.0176987
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0176935
ZNF846 zinc finger protein 846 0.0176486
AXIN1 axin 1 0.0176483
USP9X ubiquitin specific peptidase 9, X-linked 0.0176137
ABHD18 abhydrolase domain containing 18 0.0175803
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.0175674
LDHB lactate dehydrogenase B 0.0175666
CHD1 chromodomain helicase DNA binding protein 1 0.0175441
CENPO centromere protein O 0.0175193
KIF22 kinesin family member 22 0.0174973
ZNF7 zinc finger protein 7 0.0174903
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0174894
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0174191
NCLN nicalin 0.0173948
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.0173846
OAZ1 ornithine decarboxylase antizyme 1 0.0173491
XPO4 exportin 4 0.0173414
LSG1 large 60S subunit nuclear export GTPase 1 0.0173407
ACBD3 acyl-CoA binding domain containing 3 0.0173019
DNM1 dynamin 1 0.017297
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.0172914
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0172339
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.0171773
RBM38 RNA binding motif protein 38 0.0171578
RBM19 RNA binding motif protein 19 0.0171218
PELP1 proline, glutamate and leucine rich protein 1 0.0171103
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.0171076
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0170526
MYDGF myeloid-derived growth factor 0.0170468
UFD1 ubiquitin recognition factor in ER associated degradation 1 0.0170406
RPL11 ribosomal protein L11 0.0170095
SEC63 SEC63 homolog (S. cerevisiae) 0.0169912
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.0169411
DCP2 decapping mRNA 2 0.0169113
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0169074
SGMS1 sphingomyelin synthase 1 0.0169024
FAM184A family with sequence similarity 184, member A 0.0168733
HYOU1 hypoxia up-regulated 1 0.0168214
CCDC85B coiled-coil domain containing 85B 0.0168205
LIMS1 LIM and senescent cell antigen-like domains 1 0.0168138
TEC tec protein tyrosine kinase 0.0167564
TRAPPC11 trafficking protein particle complex 11 0.0167245
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0167069
PRKD2 protein kinase D2 0.0166947
DTNBP1 dystrobrevin binding protein 1 0.0165972
RUBCN rubicon autophagy regulator 0.016593
RNF111 ring finger protein 111 0.0165416
ZNF367 zinc finger protein 367 0.0165406
RAB27B RAB27B, member RAS oncogene family 0.0165079
ADGRE5 adhesion G protein-coupled receptor E5 0.0164826
CD44 CD44 molecule (Indian blood group) 0.0164709
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.0164681
MRRF mitochondrial ribosome recycling factor 0.0164621
SMG9 SMG9 nonsense mediated mRNA decay factor 0.0164262
UBE2Z ubiquitin-conjugating enzyme E2Z 0.016421
METAP2 methionyl aminopeptidase 2 0.0164202
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0164112
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.0164032
MEGF8 multiple EGF-like-domains 8 0.016396
RBM25 RNA binding motif protein 25 0.0163881
CTBS chitobiase, di-N-acetyl- 0.0163594
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.0163506
GDF15 growth differentiation factor 15 0.0163282
RAN RAN, member RAS oncogene family 0.0163191
SSBP4 single stranded DNA binding protein 4 0.016281
NIBAN2 niban apoptosis regulator 2 0.0162746
ZNF37A zinc finger protein 37A 0.0162485
MED13 mediator complex subunit 13 0.0162373
IPP intracisternal A particle-promoted polypeptide 0.0162083
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.0161786
TNRC6A trinucleotide repeat containing 6A 0.0161659
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.0161318
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.016127
C19ORF53 chromosome 19 open reading frame 53 0.0161206
RPS10 ribosomal protein S10 0.0161179
TUT4 terminal uridylyl transferase 4 0.0161162
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.0160843
CADM2 cell adhesion molecule 2 0.0160672
UBE4A ubiquitination factor E4A 0.0160647
CDK5RAP1 CDK5 regulatory subunit associated protein 1 0.0160589
TRIP4 thyroid hormone receptor interactor 4 0.0160487
TMEM117 transmembrane protein 117 0.0160399
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0160361
UBE2I ubiquitin-conjugating enzyme E2I 0.0160338
RPAP2 RNA polymerase II associated protein 2 0.0160233
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0160221
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0160168
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.0160029
SMAD3 SMAD family member 3 0.0159581
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.015954
EZR ezrin 0.015938
RAVER1 ribonucleoprotein, PTB-binding 1 0.0159318
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0159238
USP45 ubiquitin specific peptidase 45 0.0158835
ESYT2 extended synaptotagmin-like protein 2 0.0158498
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 0.0158316
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0158209
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0158176
COPE coatomer protein complex, subunit epsilon 0.0157908
ZMYM5 zinc finger, MYM-type 5 0.0157822
CERCAM cerebral endothelial cell adhesion molecule 0.0157682
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.0157298
GRAP2 GRB2-related adaptor protein 2 0.0157241
MIPEP mitochondrial intermediate peptidase 0.0157223
ERCC6 excision repair cross-complementation group 6 0.015722
ZFAND6 zinc finger, AN1-type domain 6 0.0156858
ZDHHC5 zinc finger, DHHC-type containing 5 0.0156856
TMEM135 transmembrane protein 135 0.0156726

decreased expression

Symbol Name Standardized Value
ARL15 ADP-ribosylation factor-like 15 -0.175049
SMYD3 SET and MYND domain containing 3 -0.144727
EPB41 erythrocyte membrane protein band 4.1 -0.0853692
ADGRB3 adhesion G protein-coupled receptor B3 -0.0625034
KRT8 keratin 8, type II -0.0605247
PRKCB protein kinase C, beta -0.0548509
ZFPM2 zinc finger protein, FOG family member 2 -0.0545621
CHD9 chromodomain helicase DNA binding protein 9 -0.0537394
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.053544
MED13L mediator complex subunit 13-like -0.053413
PRKCA protein kinase C, alpha -0.0519873
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0483727
PARD3B par-3 family cell polarity regulator beta -0.0481597
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0469161
HIPK2 homeodomain interacting protein kinase 2 -0.0457969
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0451121
CTBP2 C-terminal binding protein 2 -0.0449717
SQLE squalene epoxidase -0.0442717
VCL vinculin -0.0415652
PRELID2 PRELI domain containing 2 -0.0404804
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0401734
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.0400847
TFCP2 transcription factor CP2 -0.039975
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0398592
MLXIP MLX interacting protein -0.039554
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0392778
MYO18B myosin XVIIIB -0.0390156
USP32 ubiquitin specific peptidase 32 -0.0389405
ACTN4 actinin, alpha 4 -0.0388666
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0387751
ANO10 anoctamin 10 -0.0387504
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0381528
MAP4 microtubule-associated protein 4 -0.0381372
WWOX WW domain containing oxidoreductase -0.0377517
SREBF2 sterol regulatory element binding transcription factor 2 -0.0375158
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0374688
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0371952
NUSAP1 nucleolar and spindle associated protein 1 -0.0366405
WTAP Wilms tumor 1 associated protein -0.0364717
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.0364243
TASOR2 transcription activation suppressor family member 2 -0.0354262
PHKB phosphorylase kinase, beta -0.0347379
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0339587
NSD1 nuclear receptor binding SET domain protein 1 -0.0329557
MARCHF3 membrane associated ring-CH-type finger 3 -0.0326586
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0325837
BICRAL BICRA like chromatin remodeling complex associated protein -0.032566
ZFAND3 zinc finger, AN1-type domain 3 -0.0325433
LUC7L LUC7-like (S. cerevisiae) -0.0322792
POM121 POM121 transmembrane nucleoporin -0.0320491
CCDC57 coiled-coil domain containing 57 -0.0319434
SLC38A1 solute carrier family 38, member 1 -0.0317118
SFSWAP splicing factor, suppressor of white-apricot family -0.0315987
PCDH9 protocadherin 9 -0.0315547
PRKCSH protein kinase C substrate 80K-H -0.0314448
LOC112694756 uncharaterized LOC112694756 -0.0313871
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0313716
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0313587
ZEB2 zinc finger E-box binding homeobox 2 -0.0312437
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0301771
PPP4R3B protein phosphatase 4 regulatory subunit 3B -0.029811
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0295043
RORA RAR-related orphan receptor A -0.0292986
CENPE centromere protein E, 312kDa -0.0292174
NCAM2 neural cell adhesion molecule 2 -0.0284464
PHF3 PHD finger protein 3 -0.0283788
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.0283405
ELP4 elongator acetyltransferase complex subunit 4 -0.0282958
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.028171
PTBP3 polypyrimidine tract binding protein 3 -0.0281102
NR2C1 nuclear receptor subfamily 2, group C, member 1 -0.0280181
STRN3 striatin, calmodulin binding protein 3 -0.0279275
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0279163
DLG1 discs, large homolog 1 (Drosophila) -0.0277692
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0275973
FHIT fragile histidine triad -0.0275619
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0275516
PHACTR4 phosphatase and actin regulator 4 -0.0275384
BCOR BCL6 corepressor -0.0274912
KIF14 kinesin family member 14 -0.0274784
MYO1D myosin ID -0.0274566
BICD1 bicaudal D homolog 1 (Drosophila) -0.0274452
TTC17 tetratricopeptide repeat domain 17 -0.0274319
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0272504
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0271982
PHACTR2 phosphatase and actin regulator 2 -0.027198
MPHOSPH9 M-phase phosphoprotein 9 -0.026974
MSI2 musashi RNA-binding protein 2 -0.0268693
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0268059
GOLM2 golgi membrane protein 2 -0.0265695
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0265439
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0264897
GOLPH3L golgi phosphoprotein 3-like -0.0264294
ZFYVE9 zinc finger, FYVE domain containing 9 -0.026428
SSBP3 single stranded DNA binding protein 3 -0.0263766
AFF1 AF4/FMR2 family, member 1 -0.0261948
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0261876
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0261582
BCR breakpoint cluster region -0.0260824
UBAC2 UBA domain containing 2 -0.0260475
FER fer (fps/fes related) tyrosine kinase -0.0260235
SMC5 structural maintenance of chromosomes 5 -0.025983
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 -0.0259761
ELOVL6 ELOVL fatty acid elongase 6 -0.0259571
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.0258883
SKIC3 SKI3 subunit of superkiller complex -0.0254783
NLN neurolysin (metallopeptidase M3 family) -0.0253602
LARP4B La ribonucleoprotein domain family, member 4B -0.025334
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0252816
FKBP5 FK506 binding protein 5 -0.0252689
PCM1 pericentriolar material 1 -0.0252584
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0251853
NRDC nardilysin convertase -0.0250734
ATXN2 ataxin 2 -0.0250559
CFLAR CASP8 and FADD-like apoptosis regulator -0.0250363
CMIP c-Maf inducing protein -0.0249964
HMBOX1 homeobox containing 1 -0.024904
TCF3 transcription factor 3 -0.0248836
TTLL10 tubulin tyrosine ligase-like family member 10 -0.024778
ABHD3 abhydrolase domain containing 3 -0.0247513
RBBP6 retinoblastoma binding protein 6 -0.0246623
DCAF16 DDB1 and CUL4 associated factor 16 -0.0246382
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -0.024572
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.024464
STK4 serine/threonine kinase 4 -0.024456
STXBP4 syntaxin binding protein 4 -0.0244161
ETV6 ets variant 6 -0.0243893
AHDC1 AT hook, DNA binding motif, containing 1 -0.0241759
PRKX protein kinase, X-linked -0.0241196
RO60 Ro60, Y RNA binding protein -0.0238266
KTN1 kinectin 1 (kinesin receptor) -0.0237599
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0237155
TGFBR3 transforming growth factor, beta receptor III -0.0237128
GPBP1 GC-rich promoter binding protein 1 -0.0235955
GPHRA golgi pH regulator A -0.0235858
RABL6 RAB, member RAS oncogene family-like 6 -0.0235834
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.023445
TBCK TBC1 domain containing kinase -0.0234034
ADIPOR2 adiponectin receptor 2 -0.023403
RNF216 ring finger protein 216 -0.0233977
TRIP11 thyroid hormone receptor interactor 11 -0.023395
AHCTF1 AT hook containing transcription factor 1 -0.0233768
NFYC nuclear transcription factor Y, gamma -0.0232994
POGZ pogo transposable element with ZNF domain -0.0232834
PRRC2B proline-rich coiled-coil 2B -0.0232669
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0232611
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.0232535
MEIS2 Meis homeobox 2 -0.0231463
RBM15 RNA binding motif protein 15 -0.0230934
FBH1 F-box DNA helicase 1 -0.0230924
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0230756
EIF3M eukaryotic translation initiation factor 3, subunit M -0.0230263
SERGEF secretion regulating guanine nucleotide exchange factor -0.0229648
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0229405
MKI67 marker of proliferation Ki-67 -0.0228976
PRAME preferentially expressed antigen in melanoma -0.0228757
SHLD2 shieldin complex subunit 2 -0.0227634
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0227238
BCL2L1 BCL2-like 1 -0.022656
STIM1 stromal interaction molecule 1 -0.022641
NOL9 nucleolar protein 9 -0.0225857
KIAA1958 KIAA1958 -0.0225541
TMEM116 transmembrane protein 116 -0.0225267
STAU1 staufen double-stranded RNA binding protein 1 -0.0225176
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0225163
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0224797
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0224693
CDK17 cyclin-dependent kinase 17 -0.0224499
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0224377
ITGB5 integrin, beta 5 -0.0223784
CENPP centromere protein P -0.0223357
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0222928
KIAA0319L KIAA0319-like -0.0222024
RNF169 ring finger protein 169 -0.0220969
EXOC6 exocyst complex component 6 -0.0220853
MIA3 melanoma inhibitory activity family, member 3 -0.0220644
TBC1D5 TBC1 domain family, member 5 -0.0220002
FANCD2 Fanconi anemia, complementation group D2 -0.0219991
SDCCAG8 serologically defined colon cancer antigen 8 -0.0219777
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0219335
SMC1A structural maintenance of chromosomes 1A -0.0219318
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0218133
PDS5A PDS5 cohesin associated factor A -0.0217912
RBM10 RNA binding motif protein 10 -0.0217456
AZIN1 antizyme inhibitor 1 -0.0216834
RPL28 ribosomal protein L28 -0.0216651
DMXL1 Dmx-like 1 -0.0216441
PTRH2 peptidyl-tRNA hydrolase 2 -0.0215797
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0214957
WARS1 tryptophanyl-tRNA synthetase 1 -0.0214006
RDX radixin -0.0213988
TPP2 tripeptidyl peptidase II -0.0213632
DSTN destrin (actin depolymerizing factor) -0.0213471
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0213275
MON2 MON2 homolog (S. cerevisiae) -0.0213172
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0212591
RREB1 ras responsive element binding protein 1 -0.0212511
FAM171A1 family with sequence similarity 171, member A1 -0.0211793
FBXO42 F-box protein 42 -0.0211662
RPL8 ribosomal protein L8 -0.0211165
DCHS2 dachsous cadherin-related 2 -0.0210871
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0209226
USP48 ubiquitin specific peptidase 48 -0.0208387
PTPRC protein tyrosine phosphatase, receptor type, C -0.0208386
USP8 ubiquitin specific peptidase 8 -0.0208366
NUDCD3 NudC domain containing 3 -0.0207853
RRBP1 ribosome binding protein 1 -0.0207384
AIG1 androgen-induced 1 -0.0207275
ENSA endosulfine alpha -0.020704
OGA O-GlcNAcase -0.0206504
PCCA propionyl CoA carboxylase, alpha polypeptide -0.0206395
RAB28 RAB28, member RAS oncogene family -0.0206133
MZF1 myeloid zinc finger 1 -0.0204384
SUMF1 sulfatase modifying factor 1 -0.0204275
TCF12 transcription factor 12 -0.0204101
JPT1 Jupiter microtubule associated homolog 1 -0.0203873
RPSA ribosomal protein SA -0.0203173
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0202857
ZNF292 zinc finger protein 292 -0.020266
SEPTIN9 septin 9 -0.0201556
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.0201419
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.020108
PTPRB protein tyrosine phosphatase, receptor type, B -0.0200717
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0200108
KAT6A K(lysine) acetyltransferase 6A -0.0199765
ADAM10 ADAM metallopeptidase domain 10 -0.0199139
XPOT exportin, tRNA -0.0198904
SCFD1 sec1 family domain containing 1 -0.0198177
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -0.0198129
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0198087
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.0198073
MMS22L MMS22-like, DNA repair protein -0.0197762
CNTNAP2 contactin associated protein-like 2 -0.0197204
BPTF bromodomain PHD finger transcription factor -0.019643
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -0.0195999
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.0195852
STAT5A signal transducer and activator of transcription 5A -0.0195186
DSTYK dual serine/threonine and tyrosine protein kinase -0.0195179
ZBTB20 zinc finger and BTB domain containing 20 -0.0195167
ZNF518A zinc finger protein 518A -0.0195148
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -0.0193659
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0193378
SCFD2 sec1 family domain containing 2 -0.0193321
CLASP1 cytoplasmic linker associated protein 1 -0.0193135
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.0192833
IPO9 importin 9 -0.0192774
DLG5 discs, large homolog 5 (Drosophila) -0.01919
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -0.0191367
ATRN attractin -0.0191007
WDPCP WD repeat containing planar cell polarity effector -0.0190725
CEP170 centrosomal protein 170kDa -0.0190654
NCOR1 nuclear receptor corepressor 1 -0.0190045
WDFY2 WD repeat and FYVE domain containing 2 -0.0188958
SZRD1 SUZ RNA binding domain containing 1 -0.0188853
PRCC papillary renal cell carcinoma (translocation-associated) -0.0188064
SNAP29 synaptosomal-associated protein, 29kDa -0.0187884
MACC1 metastasis associated in colon cancer 1 -0.018783
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -0.0186329
TUBB tubulin, beta class I -0.0186293
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.0185762
RPS7 ribosomal protein S7 -0.0185674
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0185025
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0184558
TSC22D2 TSC22 domain family, member 2 -0.0183795
YEATS2 YEATS domain containing 2 -0.0183642
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0182953
INO80D INO80 complex subunit D -0.0182907
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa -0.0181995
ANLN anillin, actin binding protein -0.0181696
MOB1B MOB kinase activator 1B -0.0181539
DEK DEK proto-oncogene -0.0181354
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -0.0181257
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0181243
HDLBP high density lipoprotein binding protein -0.0181235
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.0181122
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.0181076
FUBP1 far upstream element (FUSE) binding protein 1 -0.017959
TAC4 tachykinin 4 (hemokinin) -0.0179441
HDGF hepatoma-derived growth factor -0.0178944
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0178025
SSBP2 single-stranded DNA binding protein 2 -0.017776
PPME1 protein phosphatase methylesterase 1 -0.0177592
WASL Wiskott-Aldrich syndrome-like -0.0177489
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0176758
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -0.0176583
ANAPC16 anaphase promoting complex subunit 16 -0.0176387
ERBIN erbb2 interacting protein -0.0175977
CTNNBIP1 catenin, beta interacting protein 1 -0.0175947
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0175822
ZRANB2 zinc finger, RAN-binding domain containing 2 -0.0175595
SENP1 SUMO1/sentrin specific peptidase 1 -0.0175506
MED24 mediator complex subunit 24 -0.017504
MASTL microtubule associated serine/threonine kinase-like -0.017495
DNM2 dynamin 2 -0.0174544
SNX1 sorting nexin 1 -0.0174349
NUP133 nucleoporin 133kDa -0.0174068
UBN2 ubinuclein 2 -0.0174046
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -0.0173919
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0173678
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.017359
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.0172909
SCAP SREBF chaperone -0.0172632
FAR1 fatty acyl CoA reductase 1 -0.0172618
FOXJ3 forkhead box J3 -0.0172338
LRRC41 leucine rich repeat containing 41 -0.0171852
ZC3H13 zinc finger CCCH-type containing 13 -0.0171715
H1-10 H1.10 linker histone -0.0171515
RBL1 retinoblastoma-like 1 -0.0171481
PCED1B PC-esterase domain containing 1B -0.0170918
ZDHHC17 zinc finger, DHHC-type containing 17 -0.0170507
TENT4B terminal nucleotidyltransferase 4B -0.0170433
RFWD3 ring finger and WD repeat domain 3 -0.0170123
UBB ubiquitin B -0.0170008
SNX25 sorting nexin 25 -0.0169953
AATF apoptosis antagonizing transcription factor -0.0169811
MITF microphthalmia-associated transcription factor -0.0169724
NUP98 nucleoporin 98kDa -0.0168749
TOR1B torsin family 1, member B (torsin B) -0.0168681
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0168677
PTK2B protein tyrosine kinase 2 beta -0.0168664
GPC5 glypican 5 -0.0168548
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -0.0168503
ELOVL5 ELOVL fatty acid elongase 5 -0.016841
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0168368
ATP5MC3 ATP synthase membrane subunit c locus 3 -0.016835
TMPO thymopoietin -0.0167788
SEC11A SEC11 homolog A (S. cerevisiae) -0.0167654
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0167309
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0166887
HSPA4L heat shock 70kDa protein 4-like -0.0166879
KNL1 kinetochore scaffold 1 -0.0166846
TNRC18 trinucleotide repeat containing 18 -0.0166699
ZC3H7A zinc finger CCCH-type containing 7A -0.0165907
RPS19 ribosomal protein S19 -0.0165714
RPL7L1 ribosomal protein L7-like 1 -0.0165539
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.0165394
MYO18A myosin XVIIIA -0.0165204
KMT2E lysine (K)-specific methyltransferase 2E -0.0165147
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0164937
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0164835
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0164821
ARB2A ARB2 cotranscriptional regulator A -0.0164312
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0164083
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0163879
GUSB glucuronidase, beta -0.0163796
TXN2 thioredoxin 2 -0.0163316
VPS35L VPS35 endosomal protein sorting factor like -0.0163275
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.016321
FKBP15 FK506 binding protein 15, 133kDa -0.0163039
RPL3 ribosomal protein L3 -0.0162902
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.0162864
GIGYF2 GRB10 interacting GYF protein 2 -0.0162853
CORO2A coronin, actin binding protein, 2A -0.0162789
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.0162666
ZBTB11 zinc finger and BTB domain containing 11 -0.0162611
WDR45 WD repeat domain 45 -0.0162447
RBM14-RBM4 RBM14-RBM4 readthrough -0.0162265
SNX2 sorting nexin 2 -0.0162088
MCM9 minichromosome maintenance complex component 9 -0.0161682
ELP3 elongator acetyltransferase complex subunit 3 -0.0161082
SNX3 sorting nexin 3 -0.0160611
IQCB1 IQ motif containing B1 -0.0160547
PARP1 poly (ADP-ribose) polymerase 1 -0.0160541
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.0160504
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.0160483
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0160229
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -0.0160026
ESYT1 extended synaptotagmin-like protein 1 -0.0159373
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0159235
CANX calnexin -0.0159168
CCNA2 cyclin A2 -0.0159029
TMEM63A transmembrane protein 63A -0.015902
ARID4A AT rich interactive domain 4A (RBP1-like) -0.015894
ATP5F1D ATP synthase F1 subunit delta -0.0158844
TSLIG1 tRNA splicing ligase complex subunit 1 -0.015852
DGKD diacylglycerol kinase, delta 130kDa -0.0158402
POU2F1 POU class 2 homeobox 1 -0.0158365
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0158345
SH3D19 SH3 domain containing 19 -0.015822
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -0.0157859
QRICH1 glutamine-rich 1 -0.0157808
SCLT1 sodium channel and clathrin linker 1 -0.0157496
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0157432
ZFYVE28 zinc finger, FYVE domain containing 28 -0.0157412
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0157336
DCTN4 dynactin 4 (p62) -0.0156976
KANTR KDM5C adjacent non-coding transcript -0.0156558
ZNF215 zinc finger protein 215 -0.015625
MANBA mannosidase, beta A, lysosomal -0.0156224
RSRC2 arginine/serine-rich coiled-coil 2 -0.0156041
UBE3C ubiquitin protein ligase E3C -0.0155898
FCHO2 FCH domain only 2 -0.0155836
FBXL18 F-box and leucine-rich repeat protein 18 -0.0155709
ANKRD28 ankyrin repeat domain 28 -0.0155421
VRK2 vaccinia related kinase 2 -0.0155223
FN1 fibronectin 1 -0.0155156
UBE3A ubiquitin protein ligase E3A -0.0155107
GGPS1 geranylgeranyl diphosphate synthase 1 -0.0155067
CUL4A cullin 4A -0.0155033
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.0154938
RABEPK Rab9 effector protein with kelch motifs -0.0154855
NANS N-acetylneuraminic acid synthase -0.0154451
HDAC8 histone deacetylase 8 -0.0154043
ATAD2 ATPase family, AAA domain containing 2 -0.0154019
LTBP4 latent transforming growth factor beta binding protein 4 -0.0153712
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0153588
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0153033
PCNP PEST proteolytic signal containing nuclear protein -0.0152965
BRD4 bromodomain containing 4 -0.015293
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0152882
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0152527
COMT catechol-O-methyltransferase -0.0152337
C4ORF36 chromosome 4 open reading frame 36 -0.015232
WDR37 WD repeat domain 37 -0.0152275
LARP4 La ribonucleoprotein domain family, member 4 -0.0151935
YIPF4 Yip1 domain family, member 4 -0.0151421
TBCD tubulin folding cofactor D -0.0151415
AUH AU RNA binding protein/enoyl-CoA hydratase -0.0151299
MESD mesoderm development LRP chaperone -0.0151268
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0150876
AKAP10 A kinase (PRKA) anchor protein 10 -0.0150871
SRRM1 serine/arginine repetitive matrix 1 -0.0150832
UGCG UDP-glucose ceramide glucosyltransferase -0.0150791
PFN1 profilin 1 -0.0150643
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0150535
WSB1 WD repeat and SOCS box containing 1 -0.0150436
HMGB1 high mobility group box 1 -0.0150193
TUBA1C tubulin, alpha 1c -0.0149731
CDK19 cyclin-dependent kinase 19 -0.0149565
STX5 syntaxin 5 -0.0149458
RPS2 ribosomal protein S2 -0.0149422
BCL6 B-cell CLL/lymphoma 6 -0.0149293
ANAPC10 anaphase promoting complex subunit 10 -0.0149264
DDB1 damage-specific DNA binding protein 1, 127kDa -0.014912
FAM117A family with sequence similarity 117, member A -0.0148937
RNF182 ring finger protein 182 -0.0148713
RAB33B RAB33B, member RAS oncogene family -0.0148549
COG4 component of oligomeric golgi complex 4 -0.0148437
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0148413
DENND5B DENN/MADD domain containing 5B -0.0148138
MYO19 myosin XIX -0.0148126
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.014811
ZNF746 zinc finger protein 746 -0.0147957
NLK nemo-like kinase -0.0147879
CCDC14 coiled-coil domain containing 14 -0.0147608
TIPRL TOR signaling pathway regulator -0.0147565
NLRP1 NLR family, pyrin domain containing 1 -0.0147404
MAP1B microtubule-associated protein 1B -0.0147364
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.0147019
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a -0.0146952
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0146862
ZNF785 zinc finger protein 785 -0.0146719
AAK1 AP2 associated kinase 1 -0.0146563
RCL1 RNA terminal phosphate cyclase-like 1 -0.0146458
UBAP2 ubiquitin associated protein 2 -0.0146361
AP2A1 adaptor-related protein complex 2, alpha 1 subunit -0.0146343
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0146075
H4C8 H4 clustered histone 8 -0.0145952
BLTP3B bridge-like lipid transfer protein family member 3B -0.0145932
MTMR14 myotubularin related protein 14 -0.0145427
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -0.0145173
TMEM50B transmembrane protein 50B -0.0144898
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -0.0144854
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0144652
RPL35 ribosomal protein L35 -0.0144607
MIGA1 mitoguardin 1 -0.014449
EPS15 epidermal growth factor receptor pathway substrate 15 -0.014447
PNKP polynucleotide kinase 3'-phosphatase -0.0144354
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -0.0144245
ETF1 eukaryotic translation termination factor 1 -0.0144241
FYCO1 FYVE and coiled-coil domain containing 1 -0.0144234
SMAP1 small ArfGAP 1 -0.0144108
MRPS18B mitochondrial ribosomal protein S18B -0.0144076
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.014347
VTA1 vesicle (multivesicular body) trafficking 1 -0.0143064
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -0.0142764
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0142346
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -0.0142195
BIN3 bridging integrator 3 -0.0141797
EXOSC1 exosome component 1 -0.0141779
KIDINS220 kinase D-interacting substrate, 220kDa -0.0141601
DYNC2I2 dynein 2 intermediate chain 2 -0.0141533
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.0141447
COCH cochlin -0.0141332
VCF1 VCP nuclear cofactor family member 1 -0.0141098
CEP162 centrosomal protein 162kDa -0.0140952
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -0.0140825
KIFC1 kinesin family member C1 -0.0140706
AGO4 argonaute RISC catalytic component 4 -0.0140528
INCENP inner centromere protein antigens 135/155kDa -0.0140441
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.0140407
SAFB2 scaffold attachment factor B2 -0.014029
ANKFY1 ankyrin repeat and FYVE domain containing 1 -0.0140251
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 -0.0140039
LMAN2 lectin, mannose-binding 2 -0.0139913
DEPDC5 DEP domain containing 5 -0.0139909
ZC3H3 zinc finger CCCH-type containing 3 -0.0139695
DLK1 delta-like 1 homolog (Drosophila) -0.013968
GAB2 GRB2-associated binding protein 2 -0.0139501
CDC73 cell division cycle 73 -0.0139277