K562_GSK J1_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 100nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK J1_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCA protein kinase C, alpha 0.0951286
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0855709
ADGRV1 adhesion G protein-coupled receptor V1 0.0803539
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0766222
HBG1 hemoglobin, gamma A 0.0644214
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0611488
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0608619
ATF7IP2 activating transcription factor 7 interacting protein 2 0.0601371
CLEC16A C-type lectin domain family 16, member A 0.0597659
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0590708
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0576497
KDM6A lysine (K)-specific demethylase 6A 0.0550283
RHOBTB3 Rho-related BTB domain containing 3 0.0547746
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.0545472
TBC1D5 TBC1 domain family, member 5 0.0542949
AFG2A AFG2 AAA ATPase homolog A 0.0539899
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0539258
FBXL13 F-box and leucine-rich repeat protein 13 0.0521743
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0519857
SPAG9 sperm associated antigen 9 0.0477581
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0466915
KIF2A kinesin heavy chain member 2A 0.0466387
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.046197
ZMYND8 zinc finger, MYND-type containing 8 0.0459137
SRSF4 serine/arginine-rich splicing factor 4 0.0457868
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0453056
BTBD7 BTB (POZ) domain containing 7 0.0450191
ZEB2 zinc finger E-box binding homeobox 2 0.0449942
JMJD1C jumonji domain containing 1C 0.0447695
OSBPL9 oxysterol binding protein-like 9 0.0446564
MACO1 macoilin 1 0.0438479
XPO1 exportin 1 0.0437733
USP6NL USP6 N-terminal like 0.0435591
PTH2R parathyroid hormone 2 receptor 0.0434143
INVS inversin 0.0432399
SIK3 SIK family kinase 3 0.042513
STIM1 stromal interaction molecule 1 0.041337
FDPS farnesyl diphosphate synthase 0.0409304
FRYL FRY-like 0.0408189
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.0402472
H2BC15 H2B clustered histone 15 0.0398389
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0388633
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.0384499
IARS1 isoleucyl-tRNA synthetase 1 0.0384212
MED13L mediator complex subunit 13-like 0.0382175
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.0380919
CDC14A cell division cycle 14A 0.0380206
GAB2 GRB2-associated binding protein 2 0.0377989
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.0375402
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0372735
HCFC1 host cell factor C1 0.0372115
ELOVL6 ELOVL fatty acid elongase 6 0.0371232
USP3 ubiquitin specific peptidase 3 0.0369542
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0366326
ADGRB3 adhesion G protein-coupled receptor B3 0.0365915
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0365564
UBAP2 ubiquitin associated protein 2 0.0363564
ZNF106 zinc finger protein 106 0.036293
TBCE tubulin folding cofactor E 0.0361021
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.035921
GRB10 growth factor receptor-bound protein 10 0.0359164
CEP170 centrosomal protein 170kDa 0.035627
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0356178
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0356006
KAT6A K(lysine) acetyltransferase 6A 0.0354195
CKAP5 cytoskeleton associated protein 5 0.0353583
SORT1 sortilin 1 0.0353373
EIF3B eukaryotic translation initiation factor 3, subunit B 0.034962
UBE2K ubiquitin-conjugating enzyme E2K 0.0346872
KCMF1 potassium channel modulatory factor 1 0.0346578
NUP214 nucleoporin 214kDa 0.0344108
WAPL WAPL cohesin release factor 0.0342128
TENM1 teneurin transmembrane protein 1 0.034206
CACUL1 CDK2-associated, cullin domain 1 0.0337723
TFR2 transferrin receptor 2 0.0334998
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0334216
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0330848
FBXL20 F-box and leucine-rich repeat protein 20 0.0328928
TXNRD1 thioredoxin reductase 1 0.0328615
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0328509
TNIK TRAF2 and NCK interacting kinase 0.0328035
TLN1 talin 1 0.0326518
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.0325974
ANTXR2 anthrax toxin receptor 2 0.0324668
THOC2 THO complex 2 0.0322859
NUP153 nucleoporin 153kDa 0.0320239
CCAR1 cell division cycle and apoptosis regulator 1 0.0320197
TCEA1 transcription elongation factor A (SII), 1 0.0318506
DNAH14 dynein, axonemal, heavy chain 14 0.031274
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 0.0311863
PICALM phosphatidylinositol binding clathrin assembly protein 0.0309657
NVL nuclear VCP-like 0.0306969
UBE2H ubiquitin-conjugating enzyme E2H 0.0305804
ZNF609 zinc finger protein 609 0.0305234
ATG13 autophagy related 13 0.030316
CENPF centromere protein F, 350/400kDa 0.0300677
RLF rearranged L-myc fusion 0.0298831
TAOK3 TAO kinase 3 0.0297421
LUC7L LUC7-like (S. cerevisiae) 0.0296595
ATP11C ATPase, class VI, type 11C 0.0294797
OSBPL8 oxysterol binding protein-like 8 0.0293124
DENR density-regulated protein 0.0292341
LYPLA1 lysophospholipase I 0.0291023
PLPP1 phospholipid phosphatase 1 0.0290645
CORO1C coronin, actin binding protein, 1C 0.0289832
WASL Wiskott-Aldrich syndrome-like 0.0288503
PDLIM5 PDZ and LIM domain 5 0.0287391
KIAA0319L KIAA0319-like 0.0286576
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.0285675
ACLY ATP citrate lyase 0.0285333
KIAA0586 KIAA0586 0.0283392
MAP1B microtubule-associated protein 1B 0.0283092
EPB41 erythrocyte membrane protein band 4.1 0.0282626
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0281693
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0280007
AFDN afadin, adherens junction formation factor 0.0279277
EZR ezrin 0.027763
PITPNA phosphatidylinositol transfer protein, alpha 0.0276776
N4BP1 NEDD4 binding protein 1 0.0276773
KIF13A kinesin family member 13A 0.0276283
TNPO3 transportin 3 0.0275929
WDR26 WD repeat domain 26 0.0275197
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.0274273
DHCR7 7-dehydrocholesterol reductase 0.0273347
MAPK8 mitogen-activated protein kinase 8 0.0271876
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0271521
KEL Kell blood group, metallo-endopeptidase 0.027082
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0270111
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.026999
SLAIN2 SLAIN motif family, member 2 0.0269613
ZFAND3 zinc finger, AN1-type domain 3 0.0269281
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0269158
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0269036
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.0265538
NCAPG2 non-SMC condensin II complex, subunit G2 0.0265531
RREB1 ras responsive element binding protein 1 0.0264959
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0264778
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0264706
MAU2 MAU2 sister chromatid cohesion factor 0.0264687
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0264357
UBE3D ubiquitin protein ligase E3D 0.0264166
NAP1L1 nucleosome assembly protein 1-like 1 0.0264
RICTOR RPTOR independent companion of MTOR, complex 2 0.026322
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.026276
STK24 serine/threonine kinase 24 0.026274
RUFY1 RUN and FYVE domain containing 1 0.0262044
PDPK1 3-phosphoinositide dependent protein kinase 1 0.0261554
TPM3 tropomyosin 3 0.0261552
PLEC plectin 0.0261242
UIMC1 ubiquitin interaction motif containing 1 0.0260937
TULP3 tubby like protein 3 0.0258951
CHD6 chromodomain helicase DNA binding protein 6 0.0257627
NUMB numb homolog (Drosophila) 0.0256839
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0255917
COMT catechol-O-methyltransferase 0.0255678
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 0.0255148
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0254786
WAC WW domain containing adaptor with coiled-coil 0.0254749
WWOX WW domain containing oxidoreductase 0.0254666
THRAP3 thyroid hormone receptor associated protein 3 0.0253827
CENPC centromere protein C 0.0252265
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.025216
NFE2L2 nuclear factor, erythroid 2-like 2 0.0251013
YIPF4 Yip1 domain family, member 4 0.0250002
NASP nuclear autoantigenic sperm protein (histone-binding) 0.0248721
RPN1 ribophorin I 0.0248581
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.0248578
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0247247
PFDN2 prefoldin subunit 2 0.0247161
PDIA6 protein disulfide isomerase family A, member 6 0.0246886
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0246758
SCAF8 SR-related CTD-associated factor 8 0.0246484
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0245754
TCF12 transcription factor 12 0.0245531
ZC3H13 zinc finger CCCH-type containing 13 0.0245122
ZNFX1 zinc finger, NFX1-type containing 1 0.0243933
SFTPA2 surfactant protein A2 0.0243185
REPS1 RALBP1 associated Eps domain containing 1 0.0242961
FLNA filamin A, alpha 0.0242647
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.0242642
FLYWCH1 FLYWCH-type zinc finger 1 0.0242516
PCM1 pericentriolar material 1 0.0241882
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0240582
GDNF glial cell derived neurotrophic factor 0.0240581
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.0239786
CLASRP CLK4-associating serine/arginine rich protein 0.0238841
CCM2 cerebral cavernous malformation 2 0.0238709
SRPK2 SRSF protein kinase 2 0.0237235
FHIT fragile histidine triad 0.0237146
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0236974
CNST consortin, connexin sorting protein 0.0236086
DCP1A decapping mRNA 1A 0.0236072
ATP5F1B ATP synthase F1 subunit beta 0.0235918
MIA3 melanoma inhibitory activity family, member 3 0.0235659
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0235055
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0233071
LRP5 low density lipoprotein receptor-related protein 5 0.0232711
MEIOB meiosis specific with OB domains 0.0232553
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0231868
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0230929
CAB39 calcium binding protein 39 0.0230328
MARCHF3 membrane associated ring-CH-type finger 3 0.0230213
TRIM27 tripartite motif containing 27 0.0230108
INTS7 integrator complex subunit 7 0.0230014
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0228485
SELENOI selenoprotein I 0.0227112
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0226841
SMG7 SMG7 nonsense mediated mRNA decay factor 0.022426
YAF2 YY1 associated factor 2 0.0224061
ZNF445 zinc finger protein 445 0.0223421
DIDO1 death inducer-obliterator 1 0.0223326
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.0222537
MED15 mediator complex subunit 15 0.0221558
CYBA cytochrome b-245, alpha polypeptide 0.0221183
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.0220837
NPEPPS aminopeptidase puromycin sensitive 0.0220826
UVRAG UV radiation resistance associated 0.0220813
PTPRH protein tyrosine phosphatase, receptor type, H 0.022065
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.0220632
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0219901
AFG3L2 AFG3-like AAA ATPase 2 0.0219322
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.0219088
TPX2 TPX2, microtubule-associated 0.0218712
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.021868
RPL35 ribosomal protein L35 0.0218458
FARSA phenylalanyl-tRNA synthetase, alpha subunit 0.0218273
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.021791
MYLIP myosin regulatory light chain interacting protein 0.0217756
NGLY1 N-glycanase 1 0.0217714
PCSK6 proprotein convertase subtilisin/kexin type 6 0.021764
WDR44 WD repeat domain 44 0.0217141
KDM4B lysine (K)-specific demethylase 4B 0.0216406
FNBP4 formin binding protein 4 0.0215768
TM7SF3 transmembrane 7 superfamily member 3 0.02156
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0215532
CAND1 cullin-associated and neddylation-dissociated 1 0.0215461
CHSY1 chondroitin sulfate synthase 1 0.0214068
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0213896
ANAPC16 anaphase promoting complex subunit 16 0.0213416
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.021325
PDIA3 protein disulfide isomerase family A, member 3 0.0212991
IGSF1 immunoglobulin superfamily, member 1 0.0212733
AP3M1 adaptor-related protein complex 3, mu 1 subunit 0.0212726
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0211771
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0210962
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0210674
ELL elongation factor RNA polymerase II 0.0210149
CEP250 centrosomal protein 250kDa 0.0210128
SNU13 small nuclear ribonucleoprotein 13 0.0209659
RAB6A RAB6A, member RAS oncogene family 0.0209455
C2CD3 C2 calcium-dependent domain containing 3 0.0209225
ANKRD26 ankyrin repeat domain 26 0.0207916
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.0207901
RUNX1 runt-related transcription factor 1 0.0207833
ATF6 activating transcription factor 6 0.0207791
POLK polymerase (DNA directed) kappa 0.020741
POM121C POM121 transmembrane nucleoporin C 0.0206772
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.0206678
TARS1 threonyl-tRNA synthetase 1 0.0206134
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.0206028
SOCS4 suppressor of cytokine signaling 4 0.020554
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.020546
SASH1 SAM and SH3 domain containing 1 0.0205443
GID8 GID complex subunit 8 0.020532
SERINC3 serine incorporator 3 0.0205168
MYO18A myosin XVIIIA 0.0205128
CFAP161 cilia and flagella associated protein 161 0.0204377
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0203283
ANO6 anoctamin 6 0.0203033
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0202901
THRB thyroid hormone receptor, beta 0.0202885
AHCTF1 AT hook containing transcription factor 1 0.0202613
KMT2D lysine (K)-specific methyltransferase 2D 0.0202382
KLHL8 kelch-like family member 8 0.0202031
KDM2B lysine (K)-specific demethylase 2B 0.0201938
RPS14 ribosomal protein S14 0.0201879
RBM4 RNA binding motif protein 4 0.0201072
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.0200892
MTF2 metal response element binding transcription factor 2 0.0200778
PHF21A PHD finger protein 21A 0.0199303
RYBP RING1 and YY1 binding protein 0.019872
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0198382
UBA6 ubiquitin-like modifier activating enzyme 6 0.0198208
TM9SF4 transmembrane 9 superfamily protein member 4 0.0198187
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.0198077
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 0.0197776
TESC tescalcin 0.0197534
EDARADD EDAR-associated death domain 0.019692
ADD1 adducin 1 (alpha) 0.0196429
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.0196248
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0196207
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.0195843
DMTF1 cyclin D binding myb-like transcription factor 1 0.0194513
EYS eyes shut homolog (Drosophila) 0.0194079
CDC25C cell division cycle 25C 0.0193227
URI1 URI1, prefoldin-like chaperone 0.0193134
CLCN7 chloride channel, voltage-sensitive 7 0.0192932
ATP5MC1 ATP synthase membrane subunit c locus 1 0.0192907
COPS2 COP9 signalosome subunit 2 0.01926
YIPF5 Yip1 domain family, member 5 0.0192509
RNF115 ring finger protein 115 0.0192472
ADAMTSL4 ADAMTS-like 4 0.0192089
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.0192065
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0191965
RCCD1 RCC1 domain containing 1 0.019154
PEX10 peroxisomal biogenesis factor 10 0.01912
PILRB paired immunoglobin-like type 2 receptor beta 0.0190994
TMEM161A transmembrane protein 161A 0.0190596
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0190325
FNDC3B fibronectin type III domain containing 3B 0.0190022
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.0190016
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.018988
MORC2 MORC family CW-type zinc finger 2 0.018971
TEC tec protein tyrosine kinase 0.0189242
RCOR3 REST corepressor 3 0.0189015
BLVRB biliverdin reductase B 0.0188805
FAR1 fatty acyl CoA reductase 1 0.0188682
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 0.0187772
FANCI Fanconi anemia, complementation group I 0.0187507
MAPK1 mitogen-activated protein kinase 1 0.0186651
RAP1A RAP1A, member of RAS oncogene family 0.0186116
NEK7 NIMA-related kinase 7 0.0185524
SNX6 sorting nexin 6 0.0185397
LRP6 low density lipoprotein receptor-related protein 6 0.0185153
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0184977
PIBF1 progesterone immunomodulatory binding factor 1 0.0184902
SUCO SUN domain containing ossification factor 0.0184477
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0184041
CDK13 cyclin-dependent kinase 13 0.0183939
ARF3 ADP-ribosylation factor 3 0.0183808
USP21 ubiquitin specific peptidase 21 0.0183477
RACK1 receptor for activated C kinase 1 0.0183412
ZNF367 zinc finger protein 367 0.0183225
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0183123
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.0182416
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0182042
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.0181499
UBP1 upstream binding protein 1 (LBP-1a) 0.0181374
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0181177
ARG2 arginase 2 0.0181136
ZNF24 zinc finger protein 24 0.0180959
CNTRL centriolin 0.018073
ZCCHC7 zinc finger, CCHC domain containing 7 0.0180725
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0180631
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C 0.0180262
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.0179959
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 0.0179654
PARD3B par-3 family cell polarity regulator beta 0.0179653
TMEM41B transmembrane protein 41B 0.017928
NOL9 nucleolar protein 9 0.0179273
MAPK6 mitogen-activated protein kinase 6 0.0179156
NIPBL Nipped-B homolog (Drosophila) 0.0178975
RHEB Ras homolog enriched in brain 0.0178864
SECISBP2L SECIS binding protein 2-like 0.0178402
SAP130 Sin3A-associated protein, 130kDa 0.0177607
EIPR1 EARP complex and GARP complex interacting protein 1 0.0177382
RAB31 RAB31, member RAS oncogene family 0.0176769
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0176759
TUSC3 tumor suppressor candidate 3 0.017637
QPRT quinolinate phosphoribosyltransferase 0.0176015
PRR12 proline rich 12 0.0175865
GIPR gastric inhibitory polypeptide receptor 0.0175733
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0175658
CSDE1 cold shock domain containing E1, RNA-binding 0.0175558
SCG3 secretogranin III 0.0175554
CMIP c-Maf inducing protein 0.0175511
ZBTB4 zinc finger and BTB domain containing 4 0.0175182
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0174943
MTMR1 myotubularin related protein 1 0.0174819
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0174602
RNF214 ring finger protein 214 0.0174462
HOOK2 hook microtubule-tethering protein 2 0.0174447
ZNF654 zinc finger protein 654 0.0174441
RPS2 ribosomal protein S2 0.0174174
COX6C cytochrome c oxidase subunit VIc 0.0173908
TTC28 tetratricopeptide repeat domain 28 0.0173811
URM1 ubiquitin related modifier 1 0.0173702
ATG2A autophagy related 2A 0.0173652
TMCO1 transmembrane and coiled-coil domains 1 0.0173567
IFT122 intraflagellar transport 122 0.0173099
TMX4 thioredoxin-related transmembrane protein 4 0.0173069
NCKAP1 NCK-associated protein 1 0.0172629
EGF epidermal growth factor 0.0172628
BABAM2 BRISC and BRCA1 A complex member 2 0.0172218
SETD2 SET domain containing 2 0.0171911
ZYG11A zyg-11 family member A, cell cycle regulator 0.017178
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.017173
ZFP64 ZFP64 zinc finger protein 0.0171659
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0171578
RAB10 RAB10, member RAS oncogene family 0.0171301
TXNDC11 thioredoxin domain containing 11 0.0171202
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.0171119
ZNF586 zinc finger protein 586 0.0169738
GOSR1 golgi SNAP receptor complex member 1 0.0169656
CEP162 centrosomal protein 162kDa 0.0169649
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.01696
NIPAL3 NIPA-like domain containing 3 0.0169532
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.0169017
SEC11A SEC11 homolog A (S. cerevisiae) 0.0168793
PKN2 protein kinase N2 0.0168763
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.0168689
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.0168254
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0168081
VCP valosin containing protein 0.0168011
FAM174B family with sequence similarity 174, member B 0.0167585
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0167391
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0167358
AGO3 argonaute RISC catalytic component 3 0.0167217
SIL1 SIL1 nucleotide exchange factor 0.0166978
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.0166486
CALN1 calneuron 1 0.0166325
BCCIP BRCA2 and CDKN1A interacting protein 0.016608
ZNF236 zinc finger protein 236 0.0166059
EPAS1 endothelial PAS domain protein 1 0.0166019
RBBP6 retinoblastoma binding protein 6 0.0165988
RCL1 RNA terminal phosphate cyclase-like 1 0.0165817
SETDB2 SET domain, bifurcated 2 0.0165813
CCDC142 coiled-coil domain containing 142 0.0165813
FRMD3 FERM domain containing 3 0.0165703
SEM1 SEM1 26S proteasome subunit 0.0165668
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.0165656
WSB1 WD repeat and SOCS box containing 1 0.0165533
GTF2A2 general transcription factor IIA, 2, 12kDa 0.0165499
RNF144A ring finger protein 144A 0.0165482
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.0165355
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.0165262
TBK1 TANK-binding kinase 1 0.0165064
WDFY3 WD repeat and FYVE domain containing 3 0.0164209
FUS FUS RNA binding protein 0.0164138
ATP5F1C ATP synthase F1 subunit gamma 0.0163972
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 0.0163941
NSRP1 nuclear speckle splicing regulatory protein 1 0.0163874
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.0163731
KIAA1191 KIAA1191 0.0163687
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.016368
YDJC YdjC homolog (bacterial) 0.0163634
DNM1L dynamin 1-like 0.0163598
BLTP3B bridge-like lipid transfer protein family member 3B 0.0163203
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.0163178
MON2 MON2 homolog (S. cerevisiae) 0.0162834
PKM pyruvate kinase, muscle 0.0162822
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0162718
ZNF346 zinc finger protein 346 0.016235
SMC6 structural maintenance of chromosomes 6 0.0161707
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 0.01617
STK4 serine/threonine kinase 4 0.0161673
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.0161628
CSPP1 centrosome and spindle pole associated protein 1 0.0161419
USP15 ubiquitin specific peptidase 15 0.0161137
CELF1 CUGBP, Elav-like family member 1 0.0161095
MKI67 marker of proliferation Ki-67 0.0161071
CUL4B cullin 4B 0.0161061
GMPR guanosine monophosphate reductase 0.0160868
NEBL nebulette 0.0160835
TMEM223 transmembrane protein 223 0.016072
ZNF431 zinc finger protein 431 0.016048
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.0159897
SET SET nuclear proto-oncogene 0.0159701
NSD1 nuclear receptor binding SET domain protein 1 0.0159366
OCIAD1 OCIA domain containing 1 0.0159157
PHIP pleckstrin homology domain interacting protein 0.0159064
PELP1 proline, glutamate and leucine rich protein 1 0.0159056
PACS1 phosphofurin acidic cluster sorting protein 1 0.015898
PHACTR2 phosphatase and actin regulator 2 0.0158658
SEPTIN6 septin 6 0.0158557
LEMD3 LEM domain containing 3 0.0158555
VPS35L VPS35 endosomal protein sorting factor like 0.0158541
RESF1 retroelement silencing factor 1 0.0158523
CDC42 cell division cycle 42 0.0158477
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0158192
PRPF4B pre-mRNA processing factor 4B 0.0157905
THUMPD2 THUMP domain containing 2 0.0157855
TRPS1 trichorhinophalangeal syndrome I 0.0157617
IST1 increased sodium tolerance 1 homolog (yeast) 0.0157517
GRB2 growth factor receptor-bound protein 2 0.0157345
LRP10 low density lipoprotein receptor-related protein 10 0.0157281
PHTF2 putative homeodomain transcription factor 2 0.0157225
FAM76B family with sequence similarity 76, member B 0.0157056
TMEM131L transmembrane 131 like 0.0156888
M6PR mannose-6-phosphate receptor (cation dependent) 0.0156832
GLG1 golgi glycoprotein 1 0.0156826
TRIM66 tripartite motif containing 66 0.0155854
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0155542
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.0155402
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0155312
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.0155138
RARS1 arginyl-tRNA synthetase 1 0.015513
ACD adrenocortical dysplasia homolog (mouse) 0.0154919
ACIN1 apoptotic chromatin condensation inducer 1 0.0154783
NEB nebulin 0.0154719
SEC31A SEC31 homolog A (S. cerevisiae) 0.0154674
RPS18 ribosomal protein S18 0.0154616
SSX3 synovial sarcoma, X breakpoint 3 0.015453
CRTAC1 cartilage acidic protein 1 0.0154497
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0154455
RPL11 ribosomal protein L11 0.0154204
RAB22A RAB22A, member RAS oncogene family 0.0154197
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0153909
DGLUCY D-glutamate cyclase 0.0153818
NOCT nocturnin 0.0153749

decreased expression

Symbol Name Standardized Value
VCL vinculin -0.0745647
TLK1 tousled-like kinase 1 -0.071355
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0709286
AK1 adenylate kinase 1 -0.0655594
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0653188
SLC38A1 solute carrier family 38, member 1 -0.0647678
SETD5 SET domain containing 5 -0.0597396
HIP1 huntingtin interacting protein 1 -0.0581903
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0571162
USP32 ubiquitin specific peptidase 32 -0.0524861
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0523744
SRRM2 serine/arginine repetitive matrix 2 -0.0522453
RC3H1 ring finger and CCCH-type domains 1 -0.0521055
PTK2 protein tyrosine kinase 2 -0.044293
RPS11 ribosomal protein S11 -0.044253
NCAM2 neural cell adhesion molecule 2 -0.0441988
VMP1 vacuole membrane protein 1 -0.0434293
EXOC4 exocyst complex component 4 -0.043395
SFPQ splicing factor proline/glutamine-rich -0.0431085
NCOR1 nuclear receptor corepressor 1 -0.0427377
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0427361
SETX senataxin -0.0423664
BCR breakpoint cluster region -0.0418011
FAF1 Fas (TNFRSF6) associated factor 1 -0.0417474
MGA MGA, MAX dimerization protein -0.0408593
DNM2 dynamin 2 -0.0407785
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0394164
MDN1 MDN1, midasin homolog (yeast) -0.0392793
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0389458
SLTM SAFB-like, transcription modulator -0.0389323
SQSTM1 sequestosome 1 -0.0387702
DST dystonin -0.0383519
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0382608
AFF1 AF4/FMR2 family, member 1 -0.0381847
ACTN4 actinin, alpha 4 -0.0376215
ZFPM2 zinc finger protein, FOG family member 2 -0.0375688
RPL18 ribosomal protein L18 -0.0374841
TANK TRAF family member-associated NFKB activator -0.0372028
KRT8 keratin 8, type II -0.0371098
ARL15 ADP-ribosylation factor-like 15 -0.0368472
NFIA nuclear factor I/A -0.0366411
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0366273
TNRC6B trinucleotide repeat containing 6B -0.036422
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0360068
MLXIP MLX interacting protein -0.0359492
CCND3 cyclin D3 -0.0358568
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0357206
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0352964
EVL Enah/Vasp-like -0.0352942
SFSWAP splicing factor, suppressor of white-apricot family -0.0351081
KLHDC10 kelch domain containing 10 -0.0348974
CEP192 centrosomal protein 192kDa -0.0346849
GPHN gephyrin -0.0345183
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0343199
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0340796
GSE1 Gse1 coiled-coil protein -0.033648
TPST2 tyrosylprotein sulfotransferase 2 -0.0335444
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.033431
RBL1 retinoblastoma-like 1 -0.0332036
AIG1 androgen-induced 1 -0.033049
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0330466
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0329904
COG5 component of oligomeric golgi complex 5 -0.032888
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.032736
MAP4 microtubule-associated protein 4 -0.0326545
SMYD3 SET and MYND domain containing 3 -0.0325755
DGCR2 DiGeorge syndrome critical region gene 2 -0.0322847
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.0321958
LONP2 lon peptidase 2, peroxisomal -0.0321793
RPL30 ribosomal protein L30 -0.0320242
GTF2IRD1 GTF2I repeat domain containing 1 -0.031957
ASPH aspartate beta-hydroxylase -0.0318975
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0315871
CERS6 ceramide synthase 6 -0.0315166
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0314888
RAP1B RAP1B, member of RAS oncogene family -0.0313048
FANCA Fanconi anemia, complementation group A -0.0311996
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.031161
NOP58 NOP58 ribonucleoprotein -0.0310139
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0310086
FNBP1 formin binding protein 1 -0.0309289
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0308238
DTNBP1 dystrobrevin binding protein 1 -0.0306115
RPL32 ribosomal protein L32 -0.0306034
SCAF11 SR-related CTD-associated factor 11 -0.0305004
FXR1 fragile X mental retardation, autosomal homolog 1 -0.0303585
GYPE glycophorin E (MNS blood group) -0.0300585
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.029992
MRPS27 mitochondrial ribosomal protein S27 -0.0298713
QKI QKI, KH domain containing, RNA binding -0.0297392
HBG2 hemoglobin, gamma G -0.0293928
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0293494
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0292126
CLTC clathrin, heavy chain (Hc) -0.0291879
BCOR BCL6 corepressor -0.0291597
ENSA endosulfine alpha -0.029027
GNAS GNAS complex locus -0.0290003
PHKB phosphorylase kinase, beta -0.0288917
PUS7 pseudouridylate synthase 7 (putative) -0.0288837
ACACA acetyl-CoA carboxylase alpha -0.028837
ANKRD28 ankyrin repeat domain 28 -0.0287914
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0287632
CTBP2 C-terminal binding protein 2 -0.0287557
BICD1 bicaudal D homolog 1 (Drosophila) -0.0287058
BRI3BP BRI3 binding protein -0.0286082
RAB27A RAB27A, member RAS oncogene family -0.0285682
RFC2 replication factor C (activator 1) 2, 40kDa -0.0284701
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -0.0284341
RPS3 ribosomal protein S3 -0.0283378
MBD5 methyl-CpG binding domain protein 5 -0.0282085
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0281766
CHD9 chromodomain helicase DNA binding protein 9 -0.0281346
CCDC14 coiled-coil domain containing 14 -0.0280041
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0279665
WASF2 WAS protein family, member 2 -0.0278376
LMTK2 lemur tyrosine kinase 2 -0.0277098
MUSK muscle, skeletal, receptor tyrosine kinase -0.0275868
LNPK lunapark, ER junction formation factor -0.0274755
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.0274609
TJP1 tight junction protein 1 -0.0274487
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0273952
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0273512
EIF5B eukaryotic translation initiation factor 5B -0.0269353
TNPO2 transportin 2 -0.0267592
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0267113
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.0266469
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0266377
KIFC3 kinesin family member C3 -0.0266206
CENPE centromere protein E, 312kDa -0.0265441
POGZ pogo transposable element with ZNF domain -0.0263876
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.0262175
KIAA0232 KIAA0232 -0.0261386
MAML2 mastermind-like 2 (Drosophila) -0.0260176
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0258424
ZFC3H1 zinc finger, C3H1-type containing -0.0258185
CDK8 cyclin-dependent kinase 8 -0.0257083
INO80 INO80 complex subunit -0.025689
DIAPH3 diaphanous-related formin 3 -0.025531
TMEM209 transmembrane protein 209 -0.025425
PHF3 PHD finger protein 3 -0.0253851
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -0.0253724
TMEM43 transmembrane protein 43 -0.0253441
XPO4 exportin 4 -0.0253111
TBCA tubulin folding cofactor A -0.0251916
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0251698
RBM6 RNA binding motif protein 6 -0.0250804
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -0.0250382
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0250202
UFD1 ubiquitin recognition factor in ER associated degradation 1 -0.0249564
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0249344
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0249149
EXOC2 exocyst complex component 2 -0.0248548
BCAS3 breast carcinoma amplified sequence 3 -0.0247702
MYO3B myosin IIIB -0.0244994
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.0244135
AVL9 AVL9 homolog (S. cerevisiase) -0.0243353
VRK1 vaccinia related kinase 1 -0.0243323
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0242935
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -0.0241639
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.0241333
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0240431
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0239421
LDLR low density lipoprotein receptor -0.023849
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -0.0238171
CDCP1 CUB domain containing protein 1 -0.0237609
C6ORF89 chromosome 6 open reading frame 89 -0.0237051
KIF21A kinesin family member 21A -0.0236945
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0236719
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -0.0236121
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0235203
LRP12 low density lipoprotein receptor-related protein 12 -0.0235118
CAPN2 calpain 2, (m/II) large subunit -0.0234683
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0234
SCAF4 SR-related CTD-associated factor 4 -0.0233457
MAP2K1 mitogen-activated protein kinase kinase 1 -0.0232988
RPS19 ribosomal protein S19 -0.0232305
TUBB6 tubulin, beta 6 class V -0.0232137
TMEM181 transmembrane protein 181 -0.0232135
RPS7 ribosomal protein S7 -0.0232123
UBAC2 UBA domain containing 2 -0.0232101
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0231614
MCAM melanoma cell adhesion molecule -0.0231612
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0231286
ESYT1 extended synaptotagmin-like protein 1 -0.0231267
RPL8 ribosomal protein L8 -0.0230704
HMGA1 high mobility group AT-hook 1 -0.0230569
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0230376
CLASP1 cytoplasmic linker associated protein 1 -0.0229248
CUL1 cullin 1 -0.0228912
LOC112694756 uncharaterized LOC112694756 -0.0228858
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0227483
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0226313
ECSIT ECSIT signalling integrator -0.0226228
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.022621
TRIM33 tripartite motif containing 33 -0.0225955
ZCCHC8 zinc finger, CCHC domain containing 8 -0.0225709
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0225406
GPHRA golgi pH regulator A -0.0225151
DYNC2I1 dynein 2 intermediate chain 1 -0.0224914
FLNB filamin B, beta -0.0224397
CD58 CD58 molecule -0.0223788
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0223767
KIF14 kinesin family member 14 -0.0223053
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.022289
NLRP1 NLR family, pyrin domain containing 1 -0.0222787
USP48 ubiquitin specific peptidase 48 -0.0222471
DNA2 DNA replication helicase/nuclease 2 -0.0222218
PDE8A phosphodiesterase 8A -0.0221748
HSPB1 heat shock 27kDa protein 1 -0.0221388
CCDC137 coiled-coil domain containing 137 -0.0220834
LRRC8B leucine rich repeat containing 8 family, member B -0.0219231
AHI1 Abelson helper integration site 1 -0.0219101
MRPL13 mitochondrial ribosomal protein L13 -0.0217848
ANKRD11 ankyrin repeat domain 11 -0.021762
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0217253
DCTN5 dynactin 5 (p25) -0.0216879
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0216544
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0216343
SFXN1 sideroflexin 1 -0.0216258
PLD3 phospholipase D family, member 3 -0.0215478
ARID3A AT rich interactive domain 3A (BRIGHT-like) -0.0215203
GON4L gon-4-like (C. elegans) -0.0213977
ATRN attractin -0.0213675
PTMA prothymosin, alpha -0.0213208
NUDCD3 NudC domain containing 3 -0.0212773
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0212148
NUDC nudC nuclear distribution protein -0.0211955
GMPS guanine monphosphate synthase -0.0210549
WRN Werner syndrome, RecQ helicase-like -0.0209898
SLC39A3 solute carrier family 39 (zinc transporter), member 3 -0.0209432
PHACTR4 phosphatase and actin regulator 4 -0.0209309
MYO16 myosin XVI -0.0208951
LAPTM5 lysosomal protein transmembrane 5 -0.0208921
SOX6 SRY (sex determining region Y)-box 6 -0.020858
DHDDS dehydrodolichyl diphosphate synthase -0.0208378
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.0207767
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0207591
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase -0.0207505
SOGA1 suppressor of glucose, autophagy associated 1 -0.0207442
DPY19L3 dpy-19-like 3 (C. elegans) -0.0206512
KPNA1 karyopherin alpha 1 (importin alpha 5) -0.0206156
CANX calnexin -0.02061
CALU calumenin -0.0206086
STRN striatin, calmodulin binding protein -0.0206031
CADM2 cell adhesion molecule 2 -0.0204908
ADD3 adducin 3 (gamma) -0.0204856
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0204802
ZNF292 zinc finger protein 292 -0.0204792
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -0.0204574
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0204287
ATP11B ATPase, class VI, type 11B -0.0203495
FCHSD2 FCH and double SH3 domains 2 -0.0203155
PARG poly (ADP-ribose) glycohydrolase -0.0202857
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0202462
FBXO46 F-box protein 46 -0.0202432
RAD51B RAD51 paralog B -0.0202238
NOL11 nucleolar protein 11 -0.0202109
PITRM1 pitrilysin metallopeptidase 1 -0.0201746
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0201384
FBXO28 F-box protein 28 -0.020134
PLCL1 phospholipase C-like 1 -0.0201194
PRPF38B pre-mRNA processing factor 38B -0.0200708
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0200202
UNKL unkempt family zinc finger-like -0.019958
RAI1 retinoic acid induced 1 -0.0199252
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0199224
SSR4 signal sequence receptor, delta -0.0199192
ANKRD17 ankyrin repeat domain 17 -0.0198959
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0198879
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0198798
ANKRD10 ankyrin repeat domain 10 -0.0198573
NCOA3 nuclear receptor coactivator 3 -0.019826
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.0198184
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0198029
KMT2A lysine (K)-specific methyltransferase 2A -0.0197633
PCSK7 proprotein convertase subtilisin/kexin type 7 -0.0197419
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0197399
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0197055
ASXL2 additional sex combs like transcriptional regulator 2 -0.0196958
GPC6 glypican 6 -0.0196566
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0195579
ZNF804A zinc finger protein 804A -0.0195299
ZNF217 zinc finger protein 217 -0.0193572
TLK2 tousled-like kinase 2 -0.0193196
PCDH9 protocadherin 9 -0.0192194
ADGRE2 adhesion G protein-coupled receptor E2 -0.0192154
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0191992
ACBD3 acyl-CoA binding domain containing 3 -0.0191507
RPLP0 ribosomal protein, large, P0 -0.0191334
GATAD2B GATA zinc finger domain containing 2B -0.0191327
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0191095
CCDC88A coiled-coil domain containing 88A -0.0190936
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.0190707
RRBP1 ribosome binding protein 1 -0.0190607
HSF1 heat shock transcription factor 1 -0.0190451
MFGE8 milk fat globule-EGF factor 8 protein -0.0190393
NUP155 nucleoporin 155kDa -0.0190392
EIF3E eukaryotic translation initiation factor 3, subunit E -0.0190359
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0190188
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.018982
UBC ubiquitin C -0.0189574
CBR4 carbonyl reductase 4 -0.0189018
BLTP3A bridge-like lipid transfer protein family member 3A -0.0188968
TMEM167A transmembrane protein 167A -0.0188314
TMEM87A transmembrane protein 87A -0.0187077
HSPA4L heat shock 70kDa protein 4-like -0.0186397
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0186185
SEH1L SEH1-like (S. cerevisiae) -0.018617
CCDC12 coiled-coil domain containing 12 -0.018558
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0185524
TXNIP thioredoxin interacting protein -0.0185206
TGOLN2 trans-golgi network protein 2 -0.0184465
SENP5 SUMO1/sentrin specific peptidase 5 -0.0184312
HDAC3 histone deacetylase 3 -0.0184227
QSER1 glutamine and serine rich 1 -0.0184026
H3-3B H3.3 histone B -0.0183929
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0183837
BAG6 BCL2-associated athanogene 6 -0.0182854
RHAG Rh-associated glycoprotein -0.0182589
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0182567
TRIM38 tripartite motif containing 38 -0.0182292
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -0.0182205
GOLGA4 golgin A4 -0.0182157
CPPED1 calcineurin-like phosphoesterase domain containing 1 -0.018172
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.018161
KPNB1 karyopherin (importin) beta 1 -0.0181226
PTRH2 peptidyl-tRNA hydrolase 2 -0.0181166
SYCP2 synaptonemal complex protein 2 -0.0180918
UTRN utrophin -0.017988
LRRC8A leucine rich repeat containing 8 family, member A -0.0179806
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0179589
BBX bobby sox homolog (Drosophila) -0.0179352
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.0178916
MTFR1 mitochondrial fission regulator 1 -0.01789
RPL27 ribosomal protein L27 -0.0178779
PRKCB protein kinase C, beta -0.0178775
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0178586
CD44 CD44 molecule (Indian blood group) -0.0178546
SMC5 structural maintenance of chromosomes 5 -0.0178455
SFMBT2 Scm-like with four mbt domains 2 -0.0177418
PPHLN1 periphilin 1 -0.017703
NMU neuromedin U -0.0177
GSR glutathione reductase -0.0176707
SHCBP1 SHC SH2-domain binding protein 1 -0.0176452
RUVBL2 RuvB-like AAA ATPase 2 -0.0175865
UBXN2A UBX domain protein 2A -0.0175523
CLASP2 cytoplasmic linker associated protein 2 -0.01753
GLUL glutamate-ammonia ligase -0.0174839
SMIM14 small integral membrane protein 14 -0.0174818
KRI1 KRI1 homolog (S. cerevisiae) -0.0174516
TMEM168 transmembrane protein 168 -0.0174184
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -0.0174044
SCLT1 sodium channel and clathrin linker 1 -0.0174035
WDFY1 WD repeat and FYVE domain containing 1 -0.0173917
TRIM56 tripartite motif containing 56 -0.0173289
TADA3 transcriptional adaptor 3 -0.0172893
APOLD1 apolipoprotein L domain containing 1 -0.0172783
PKNOX1 PBX/knotted 1 homeobox 1 -0.0172777
OXNAD1 oxidoreductase NAD-binding domain containing 1 -0.017256
SUMF1 sulfatase modifying factor 1 -0.0172276
MSI2 musashi RNA-binding protein 2 -0.0172167
PTPRC protein tyrosine phosphatase, receptor type, C -0.0171962
NFYC nuclear transcription factor Y, gamma -0.0171866
NUP160 nucleoporin 160kDa -0.0171706
VRK2 vaccinia related kinase 2 -0.0171159
FNDC3A fibronectin type III domain containing 3A -0.0171153
FBXO11 F-box protein 11 -0.0171012
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -0.0170953
KRT18 keratin 18, type I -0.01705
SNX3 sorting nexin 3 -0.0170343
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.0169542
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0169537
TTF2 transcription termination factor, RNA polymerase II -0.0169167
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0169081
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.016895
HDAC8 histone deacetylase 8 -0.0168606
MIMS1 mitochondrial inner membrane scaffold 1 -0.0168435
IPO9 importin 9 -0.0168262
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0168202
MRPS25 mitochondrial ribosomal protein S25 -0.0167924
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0167919
RAB40C RAB40C, member RAS oncogene family -0.0167865
STAMBP STAM binding protein -0.0167776
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0167719
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0167678
RDX radixin -0.0167474
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0167453
TAOK1 TAO kinase 1 -0.0167243
TET1 tet methylcytosine dioxygenase 1 -0.0167063
NUP210 nucleoporin 210kDa -0.0166765
BRD4 bromodomain containing 4 -0.016585
MEIS2 Meis homeobox 2 -0.016585
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.0165694
PRDX5 peroxiredoxin 5 -0.0165517
RNF38 ring finger protein 38 -0.0164833
KATNBL1 katanin p80 subunit B-like 1 -0.0164589
CDC73 cell division cycle 73 -0.0164269
ECM1 extracellular matrix protein 1 -0.0163896
USP25 ubiquitin specific peptidase 25 -0.0163677
LMAN2 lectin, mannose-binding 2 -0.0163592
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0163563
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.016353
KIFAP3 kinesin-associated protein 3 -0.0163143
ZNF277 zinc finger protein 277 -0.0162817
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0162813
ETV6 ets variant 6 -0.0162793
SPPL3 signal peptide peptidase like 3 -0.0162557
MCM10 minichromosome maintenance complex component 10 -0.0162396
BTF3L4 basic transcription factor 3-like 4 -0.0162378
ARRB1 arrestin, beta 1 -0.0162372
CENPK centromere protein K -0.0162363
MZF1 myeloid zinc finger 1 -0.0161957
FAM135A family with sequence similarity 135, member A -0.0161632
MYO6 myosin VI -0.0161627
SEPTIN11 septin 11 -0.0161583
CHID1 chitinase domain containing 1 -0.0161325
SERF2 small EDRK-rich factor 2 -0.0161046
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -0.016104
APOE apolipoprotein E -0.016067
PUDP pseudouridine 5'-phosphatase -0.0160298
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.0160256
ELP6 elongator acetyltransferase complex subunit 6 -0.0160154
CDC45 cell division cycle 45 -0.0160063
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0159949
NIBAN1 niban apoptosis regulator 1 -0.01599
TGFB1 transforming growth factor, beta 1 -0.0159876
ZNF83 zinc finger protein 83 -0.0159808
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0159804
ZNF146 zinc finger protein 146 -0.0159603
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0159449
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 -0.015929
PNN pinin, desmosome associated protein -0.0159125
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0159065
YLPM1 YLP motif containing 1 -0.0157951
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0157939
ZXDC ZXD family zinc finger C -0.015792
SLF2 SMC5-SMC6 complex localization factor 2 -0.0157915
RNF114 ring finger protein 114 -0.0157718
ENO1 enolase 1, (alpha) -0.0157627
C17ORF99 chromosome 17 open reading frame 99 -0.0157603
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -0.0157429
YIPF6 Yip1 domain family, member 6 -0.015725
CNPY2 canopy FGF signaling regulator 2 -0.0156985
RPL38 ribosomal protein L38 -0.0156847
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.0156586
PAXBP1 PAX3 and PAX7 binding protein 1 -0.0156417
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0156363
GTPBP10 GTP-binding protein 10 (putative) -0.0155769
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) -0.0155601
EPM2AIP1 EPM2A (laforin) interacting protein 1 -0.015536
SSR1 signal sequence receptor, alpha -0.0155325
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.0155203
UBE2O ubiquitin-conjugating enzyme E2O -0.0155121
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.0154942
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0154689
UGDH UDP-glucose 6-dehydrogenase -0.015463
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.0153955
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0153869
RB1 retinoblastoma 1 -0.0153696
MEF2A myocyte enhancer factor 2A -0.0153516
RBMX RNA binding motif protein, X-linked -0.0153321
LBR lamin B receptor -0.0153296
SYTL2 synaptotagmin-like 2 -0.0152948
MOB1A MOB kinase activator 1A -0.0152845
METTL16 methyltransferase like 16 -0.0152839
IMMT inner membrane protein, mitochondrial -0.0152667
RCSD1 RCSD domain containing 1 -0.0152629
TSG101 tumor susceptibility 101 -0.0152564
TTC7B tetratricopeptide repeat domain 7B -0.0152291
KDM5A lysine (K)-specific demethylase 5A -0.0151759
GPATCH4 G patch domain containing 4 -0.0151531
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) -0.0151439
FANCD2 Fanconi anemia, complementation group D2 -0.0151432
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.0151131
PTMS parathymosin -0.0151028
KCTD20 potassium channel tetramerization domain containing 20 -0.015093
PEX26 peroxisomal biogenesis factor 26 -0.015083
DAND5 DAN domain family member 5, BMP antagonist -0.0150581
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) -0.0150188
SPRED2 sprouty-related, EVH1 domain containing 2 -0.015018
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0150006
CARD8 caspase recruitment domain family, member 8 -0.0149917
DCTN2 dynactin 2 (p50) -0.014961
SNAP29 synaptosomal-associated protein, 29kDa -0.0149543
HOXB3 homeobox B3 -0.0149537
CCDC32 coiled-coil domain containing 32 -0.0149514
ATF6B activating transcription factor 6 beta -0.0149484
SAE1 SUMO1 activating enzyme subunit 1 -0.0149336
PGAP6 post-GPI attachment to proteins 6 -0.0149285
PCNX4 pecanex 4 -0.0149175
FMNL3 formin-like 3 -0.0149078
PLIN4 perilipin 4 -0.014903
TRIM28 tripartite motif containing 28 -0.0148763
PPA2 pyrophosphatase (inorganic) 2 -0.0148542
RPL28 ribosomal protein L28 -0.014849
TBC1D23 TBC1 domain family, member 23 -0.0148265
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -0.0148112
USP33 ubiquitin specific peptidase 33 -0.0148077
LUZP1 leucine zipper protein 1 -0.0147749
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.0147681