K562_GSK J1_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 10nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK J1_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCA protein kinase C, alpha 0.124246
SIK3 SIK family kinase 3 0.0897274
GOLGA4 golgin A4 0.0834663
MUSK muscle, skeletal, receptor tyrosine kinase 0.0775955
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0726348
RPS2 ribosomal protein S2 0.0712498
ZEB2 zinc finger E-box binding homeobox 2 0.0703277
KMT2C lysine (K)-specific methyltransferase 2C 0.0681489
CPED1 cadherin-like and PC-esterase domain containing 1 0.0670792
KIAA1958 KIAA1958 0.0662646
CEP350 centrosomal protein 350kDa 0.0592235
FAM222B family with sequence similarity 222, member B 0.0586552
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0581852
TMEM135 transmembrane protein 135 0.0577915
SCAF11 SR-related CTD-associated factor 11 0.0569796
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0566343
MYO1D myosin ID 0.054982
KIF2A kinesin heavy chain member 2A 0.0542908
SQSTM1 sequestosome 1 0.0540596
GRB2 growth factor receptor-bound protein 2 0.0533315
PRAME preferentially expressed antigen in melanoma 0.0520785
ENO1 enolase 1, (alpha) 0.0516538
HBG1 hemoglobin, gamma A 0.0511298
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0507059
ATG7 autophagy related 7 0.0490994
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0485058
RPLP1 ribosomal protein, large, P1 0.0478696
MDN1 MDN1, midasin homolog (yeast) 0.0465484
NIPBL Nipped-B homolog (Drosophila) 0.0459949
RPS8 ribosomal protein S8 0.0459087
LARP4B La ribonucleoprotein domain family, member 4B 0.0454568
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.0448963
RNF24 ring finger protein 24 0.0445283
BCAS3 breast carcinoma amplified sequence 3 0.0443937
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0441044
WDR4 WD repeat domain 4 0.04359
AHDC1 AT hook, DNA binding motif, containing 1 0.0433085
PACS1 phosphofurin acidic cluster sorting protein 1 0.0424368
CHD4 chromodomain helicase DNA binding protein 4 0.0421417
CLTC clathrin, heavy chain (Hc) 0.041809
ENSA endosulfine alpha 0.0417573
SMYD3 SET and MYND domain containing 3 0.0417251
INTS4 integrator complex subunit 4 0.0414071
RB1CC1 RB1-inducible coiled-coil 1 0.0411611
USP33 ubiquitin specific peptidase 33 0.0411482
NECTIN2 nectin cell adhesion molecule 2 0.0407138
RPS6 ribosomal protein S6 0.0405065
KIAA0319L KIAA0319-like 0.0404112
UBN2 ubinuclein 2 0.0396901
INSIG1 insulin induced gene 1 0.0395494
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0393627
PDLIM5 PDZ and LIM domain 5 0.0390888
DIDO1 death inducer-obliterator 1 0.0388847
ZNF106 zinc finger protein 106 0.0388589
NCOA3 nuclear receptor coactivator 3 0.0384845
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.0384162
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0373815
TOM1L2 target of myb1-like 2 (chicken) 0.0371758
ABHD3 abhydrolase domain containing 3 0.0368938
ANK1 ankyrin 1, erythrocytic 0.036144
LCLAT1 lysocardiolipin acyltransferase 1 0.0357111
SFPQ splicing factor proline/glutamine-rich 0.0355413
TRAPPC8 trafficking protein particle complex 8 0.0354478
NOL10 nucleolar protein 10 0.0352365
RAB1A RAB1A, member RAS oncogene family 0.0351068
CDC42SE2 CDC42 small effector 2 0.0349467
RNASE3 ribonuclease, RNase A family, 3 0.0348416
STON2 stonin 2 0.0347364
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0344852
RAD21 RAD21 homolog (S. pombe) 0.0341331
POTEF POTE ankyrin domain family, member F 0.0340092
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.0339271
SRRM2 serine/arginine repetitive matrix 2 0.0338277
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0336872
SRSF7 serine/arginine-rich splicing factor 7 0.0332786
U2SURP U2 snRNP-associated SURP domain containing 0.0332178
PNKD paroxysmal nonkinesigenic dyskinesia 0.0331404
ITCH itchy E3 ubiquitin protein ligase 0.0329832
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 0.0328033
AAK1 AP2 associated kinase 1 0.0328012
ZNF451 zinc finger protein 451 0.0327892
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0326624
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.032533
ATM ATM serine/threonine kinase 0.0325226
IQSEC2 IQ motif and Sec7 domain 2 0.0324965
PTPN7 protein tyrosine phosphatase, non-receptor type 7 0.0324273
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.0323932
PHF14 PHD finger protein 14 0.0323759
NUSAP1 nucleolar and spindle associated protein 1 0.0321214
TJP1 tight junction protein 1 0.0315658
KDM3B lysine (K)-specific demethylase 3B 0.031415
PLD3 phospholipase D family, member 3 0.0313672
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0312993
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0310815
MAML2 mastermind-like 2 (Drosophila) 0.0310457
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.0309795
GDNF glial cell derived neurotrophic factor 0.0308704
MYO9B myosin IXB 0.0307628
GOLM2 golgi membrane protein 2 0.0306727
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.0306084
PTH2R parathyroid hormone 2 receptor 0.0306056
KDM6A lysine (K)-specific demethylase 6A 0.0305924
RPL19 ribosomal protein L19 0.0300878
ARHGAP6 Rho GTPase activating protein 6 0.0300739
NBEAL1 neurobeachin-like 1 0.0300499
HSPA8 heat shock 70kDa protein 8 0.0300084
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0298808
RUSC2 RUN and SH3 domain containing 2 0.0297948
RPS19 ribosomal protein S19 0.0297849
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0297699
TPX2 TPX2, microtubule-associated 0.02966
ZRANB2 zinc finger, RAN-binding domain containing 2 0.029642
CENPP centromere protein P 0.0296003
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.0294165
TM9SF3 transmembrane 9 superfamily member 3 0.0291472
ADNP activity-dependent neuroprotector homeobox 0.0290736
RPL14 ribosomal protein L14 0.029045
TSC22D2 TSC22 domain family, member 2 0.0289484
MED13 mediator complex subunit 13 0.0289126
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0288177
CENPE centromere protein E, 312kDa 0.0287718
AFF4 AF4/FMR2 family, member 4 0.0286703
CRPPA CDP-L-ribitol pyrophosphorylase A 0.0283809
PDE8A phosphodiesterase 8A 0.0283794
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.0280462
WDR70 WD repeat domain 70 0.0280447
PTPRC protein tyrosine phosphatase, receptor type, C 0.0278599
SOX6 SRY (sex determining region Y)-box 6 0.0278473
YME1L1 YME1-like 1 ATPase 0.0276985
RORA RAR-related orphan receptor A 0.027691
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0276785
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0276541
MRPS35 mitochondrial ribosomal protein S35 0.0276069
ANKRD11 ankyrin repeat domain 11 0.0275603
MED15 mediator complex subunit 15 0.0274209
TPT1 tumor protein, translationally-controlled 1 0.0273432
SCFD1 sec1 family domain containing 1 0.0272896
ARHGAP21 Rho GTPase activating protein 21 0.0272747
CSNK1G2 casein kinase 1, gamma 2 0.0272302
FAM133B family with sequence similarity 133, member B 0.0271294
ARL8B ADP-ribosylation factor-like 8B 0.0271119
TMEM192 transmembrane protein 192 0.0270713
SCAF8 SR-related CTD-associated factor 8 0.0270496
RPL32 ribosomal protein L32 0.0269917
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.0268362
KEL Kell blood group, metallo-endopeptidase 0.0267618
DHDDS dehydrodolichyl diphosphate synthase 0.0266821
FOXK1 forkhead box K1 0.0266511
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.0266385
RPLP0 ribosomal protein, large, P0 0.0265872
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0264689
UBE2N ubiquitin-conjugating enzyme E2N 0.0263749
ATP11B ATPase, class VI, type 11B 0.0263694
TOR1AIP1 torsin A interacting protein 1 0.0262928
CALR calreticulin 0.0262342
CUL3 cullin 3 0.0261931
CAPN7 calpain 7 0.0261097
OXNAD1 oxidoreductase NAD-binding domain containing 1 0.0260632
INVS inversin 0.026007
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0259702
MBTD1 mbt domain containing 1 0.0259307
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0258457
SON SON DNA binding protein 0.0258348
ELF2 E74-like factor 2 (ets domain transcription factor) 0.025714
CTCF CCCTC-binding factor (zinc finger protein) 0.025655
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0256244
TOP2A topoisomerase (DNA) II alpha 170kDa 0.025465
TBCK TBC1 domain containing kinase 0.0254648
CCDC88A coiled-coil domain containing 88A 0.0253195
PUM1 pumilio RNA-binding family member 1 0.0252749
DCHS2 dachsous cadherin-related 2 0.0252455
SNX9 sorting nexin 9 0.0251134
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.0251118
CUL5 cullin 5 0.0251045
BCOR BCL6 corepressor 0.0250352
C6ORF89 chromosome 6 open reading frame 89 0.0249334
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0248742
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.0247151
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0246806
HERPUD2 HERPUD family member 2 0.0246191
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0245173
EIF3I eukaryotic translation initiation factor 3, subunit I 0.0243731
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0243543
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.0242861
CLSTN1 calsyntenin 1 0.0242668
TTC17 tetratricopeptide repeat domain 17 0.0242296
CNKSR3 CNKSR family member 3 0.0242281
MAN2A1 mannosidase, alpha, class 2A, member 1 0.0241997
STAU1 staufen double-stranded RNA binding protein 1 0.0241057
SEC24A SEC24 family member A 0.0240578
UBE3C ubiquitin protein ligase E3C 0.0240508
RPS12 ribosomal protein S12 0.0240281
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0239339
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.0238903
DOCK9 dedicator of cytokinesis 9 0.0238633
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.023727
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0236307
SLC39A11 solute carrier family 39, member 11 0.0235919
PDIA6 protein disulfide isomerase family A, member 6 0.02357
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.0234418
FNDC3A fibronectin type III domain containing 3A 0.0232943
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.023259
N4BP2L2 NEDD4 binding protein 2-like 2 0.0232536
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.0231855
MTMR3 myotubularin related protein 3 0.0231826
TOX4 TOX high mobility group box family member 4 0.0231579
FTL ferritin, light polypeptide 0.0231393
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0231348
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0231326
ERBIN erbb2 interacting protein 0.0230851
PLCD1 phospholipase C, delta 1 0.0230722
TMEM267 transmembrane protein 267 0.0230065
DSTYK dual serine/threonine and tyrosine protein kinase 0.0228419
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0226889
ADGRV1 adhesion G protein-coupled receptor V1 0.0226684
HELLS helicase, lymphoid-specific 0.0226613
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.0226312
USO1 USO1 vesicle transport factor 0.0225965
YEATS2 YEATS domain containing 2 0.0225779
KLHL18 kelch-like family member 18 0.0224056
SERP1 stress-associated endoplasmic reticulum protein 1 0.0223999
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0223678
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0222922
JMJD1C jumonji domain containing 1C 0.0222712
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.0222693
EIF3D eukaryotic translation initiation factor 3, subunit D 0.0222591
MAN1A2 mannosidase, alpha, class 1A, member 2 0.0221491
ZNF445 zinc finger protein 445 0.0220781
WNT5B wingless-type MMTV integration site family, member 5B 0.0220484
FRYL FRY-like 0.0220377
AP3M1 adaptor-related protein complex 3, mu 1 subunit 0.0220371
NOSIP nitric oxide synthase interacting protein 0.0220086
TAOK3 TAO kinase 3 0.0219996
KLHDC10 kelch domain containing 10 0.0219439
WDR41 WD repeat domain 41 0.0219096
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0217183
GRAMD1A GRAM domain containing 1A 0.0216651
HIPK3 homeodomain interacting protein kinase 3 0.0216469
CDK19 cyclin-dependent kinase 19 0.0215469
MRPL42 mitochondrial ribosomal protein L42 0.021538
SYAP1 synapse associated protein 1 0.0215364
R3HDM2 R3H domain containing 2 0.0215101
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.021448
MYADM myeloid-associated differentiation marker 0.0214151
SETD2 SET domain containing 2 0.0214067
ANKRD17 ankyrin repeat domain 17 0.0213896
PRR11 proline rich 11 0.0213195
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0213031
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0212295
KDM4B lysine (K)-specific demethylase 4B 0.0211247
ATRN attractin 0.0210407
CCDC91 coiled-coil domain containing 91 0.0210041
XYLB xylulokinase homolog (H. influenzae) 0.0210037
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.0209891
MACF1 microtubule-actin crosslinking factor 1 0.0209823
ZFYVE28 zinc finger, FYVE domain containing 28 0.0209345
VWA8 von Willebrand factor A domain containing 8 0.0209315
SPAG9 sperm associated antigen 9 0.0209007
SEC24B SEC24 family member B 0.0208939
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0208832
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0208241
CHD7 chromodomain helicase DNA binding protein 7 0.0207479
ARHGAP18 Rho GTPase activating protein 18 0.0207139
ACTG1 actin gamma 1 0.0206799
CDC123 cell division cycle 123 0.0206559
CLCN3 chloride channel, voltage-sensitive 3 0.0206267
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0205991
NCOA1 nuclear receptor coactivator 1 0.0205907
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0205787
CATSPERB catsper channel auxiliary subunit beta 0.020564
BZW2 basic leucine zipper and W2 domains 2 0.0204931
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0204871
MTA3 metastasis associated 1 family, member 3 0.0204405
RPL3L ribosomal protein L3-like 0.0204134
HIRA histone cell cycle regulator 0.0203998
RPL5 ribosomal protein L5 0.0203501
P3H1 prolyl 3-hydroxylase 1 0.0203307
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.020318
NAT10 N-acetyltransferase 10 (GCN5-related) 0.0202882
ADIPOR2 adiponectin receptor 2 0.0202495
SEPTIN6 septin 6 0.0202459
SAP130 Sin3A-associated protein, 130kDa 0.0202206
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0202151
FER fer (fps/fes related) tyrosine kinase 0.0201871
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0201012
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.0200371
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0199641
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0199426
ARHGAP12 Rho GTPase activating protein 12 0.0198964
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0198561
KIAA1191 KIAA1191 0.0198531
LIMK1 LIM domain kinase 1 0.0198088
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0197586
ZSWIM6 zinc finger, SWIM-type containing 6 0.0197321
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0197078
NUBPL nucleotide binding protein-like 0.0196861
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0196704
TCF12 transcription factor 12 0.0196636
MAP4 microtubule-associated protein 4 0.0196208
KLHL20 kelch-like family member 20 0.0196205
PEX14 peroxisomal biogenesis factor 14 0.0195043
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0194913
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0194735
PITRM1 pitrilysin metallopeptidase 1 0.019432
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0193271
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 0.0193056
ADCY8 adenylate cyclase 8 (brain) 0.0192874
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.0192828
CFDP1 craniofacial development protein 1 0.0192576
SEC62 SEC62 homolog (S. cerevisiae) 0.0192413
ASPH aspartate beta-hydroxylase 0.0191744
TAOK1 TAO kinase 1 0.0191044
NUP98 nucleoporin 98kDa 0.019079
NUMBL numb homolog (Drosophila)-like 0.0190663
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.0190576
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.0190264
RCOR1 REST corepressor 1 0.018973
LAMP1 lysosomal-associated membrane protein 1 0.0189469
NEK1 NIMA-related kinase 1 0.0189424
ABI1 abl-interactor 1 0.0188675
HMGB2 high mobility group box 2 0.0188605
ELOVL1 ELOVL fatty acid elongase 1 0.0187789
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.018722
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0187065
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.018698
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0186698
KMT2E lysine (K)-specific methyltransferase 2E 0.0186516
DESI2 desumoylating isopeptidase 2 0.0186496
PRPF6 pre-mRNA processing factor 6 0.0185857
ETF1 eukaryotic translation termination factor 1 0.0185689
ZBTB38 zinc finger and BTB domain containing 38 0.0185615
ZFAND6 zinc finger, AN1-type domain 6 0.0185469
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0185232
MEF2C myocyte enhancer factor 2C 0.0185116
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.018446
TTF1 transcription termination factor, RNA polymerase I 0.0184207
SLF1 SMC5-SMC6 complex localization factor 1 0.0183628
ATG13 autophagy related 13 0.0183126
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.0182997
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 0.0182617
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.0182593
FAM117A family with sequence similarity 117, member A 0.0182388
ZBTB35 zinc finger and BTB domain containing 35 0.0182023
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0182017
RABGAP1 RAB GTPase activating protein 1 0.0181505
MCFD2 multiple coagulation factor deficiency 2 0.0181393
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.0180328
CDC73 cell division cycle 73 0.0180264
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 0.0180121
RPL37 ribosomal protein L37 0.0179802
LSR lipolysis stimulated lipoprotein receptor 0.0179581
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.0178908
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 0.0178593
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.0178414
QRICH1 glutamine-rich 1 0.0178028
GUSB glucuronidase, beta 0.0177943
TMEM164 transmembrane protein 164 0.017702
MAP2K4 mitogen-activated protein kinase kinase 4 0.0176727
PLIN3 perilipin 3 0.0175971
RPLP2 ribosomal protein, large, P2 0.0175629
POU2F1 POU class 2 homeobox 1 0.0174791
EXPH5 exophilin 5 0.0174545
ABHD17B abhydrolase domain containing 17B 0.0174406
SEC24C SEC24 family member C 0.0174265
ENOX2 ecto-NOX disulfide-thiol exchanger 2 0.0173728
RNF216 ring finger protein 216 0.017337
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.0173022
HELQ helicase, POLQ-like 0.0171938
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0171874
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 0.0171636
NLK nemo-like kinase 0.0170712
SCAMP4 secretory carrier membrane protein 4 0.0170705
RNF13 ring finger protein 13 0.017051
CRBN cereblon 0.0170493
ZNF367 zinc finger protein 367 0.0170423
SULF2 sulfatase 2 0.0170236
TM2D1 TM2 domain containing 1 0.0169837
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.0169741
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.0169659
CMIP c-Maf inducing protein 0.016955
TET1 tet methylcytosine dioxygenase 1 0.0169057
LMAN1 lectin, mannose-binding, 1 0.0168386
MYH9 myosin, heavy chain 9, non-muscle 0.0168008
DAPK1 death-associated protein kinase 1 0.0167962
RPL35A ribosomal protein L35a 0.0167892
PHACTR2 phosphatase and actin regulator 2 0.0167885
ANO10 anoctamin 10 0.0167207
CIAO1 cytosolic iron-sulfur assembly component 1 0.0166783
SLMAP sarcolemma associated protein 0.0166264
MRPS18B mitochondrial ribosomal protein S18B 0.0165927
METTL21A methyltransferase like 21A 0.0165885
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.0165403
GPATCH8 G patch domain containing 8 0.016523
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0165149
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 0.0164805
OSBPL8 oxysterol binding protein-like 8 0.0164553
TRAK1 trafficking protein, kinesin binding 1 0.0164534
NOMO1 NODAL modulator 1 0.0164468
ACER3 alkaline ceramidase 3 0.0164222
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 0.0163976
GSPT1 G1 to S phase transition 1 0.0163852
RBM15 RNA binding motif protein 15 0.0163665
STX3 syntaxin 3 0.0163309
HP1BP3 heterochromatin protein 1, binding protein 3 0.016318
RINT1 RAD50 interactor 1 0.0162706
CFAP70 cilia and flagella associated protein 70 0.0162555
GLG1 golgi glycoprotein 1 0.0161932
PKN1 protein kinase N1 0.0161774
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0161632
RAD51B RAD51 paralog B 0.016159
TM9SF2 transmembrane 9 superfamily member 2 0.0161354
BAIAP2 BAI1-associated protein 2 0.0161301
DST dystonin 0.0160637
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0160535
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0160296
CEP57L1 centrosomal protein 57kDa-like 1 0.0160055
UBL4A ubiquitin-like 4A 0.0159419
LPAR5 lysophosphatidic acid receptor 5 0.0158782
UVRAG UV radiation resistance associated 0.0158448
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 0.0158314
FUS FUS RNA binding protein 0.0158054
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0158004
NCOR1 nuclear receptor corepressor 1 0.0157828
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.0157823
ARL15 ADP-ribosylation factor-like 15 0.0157781
DCAF6 DDB1 and CUL4 associated factor 6 0.0157721
TMEM131 transmembrane protein 131 0.0157635
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0157557
DNPEP aspartyl aminopeptidase 0.0157407
FCF1 FCF1 rRNA-processing protein 0.0157194
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.0157109
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.015648
CERCAM cerebral endothelial cell adhesion molecule 0.0156227
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.0156223
RUNX1 runt-related transcription factor 1 0.0156126
AHCYL2 adenosylhomocysteinase-like 2 0.0155985
SASS6 spindle assembly 6 homolog (C. elegans) 0.0155959
METTL2A methyltransferase like 2A 0.0155753
SMAD5 SMAD family member 5 0.0155444
EIF4E eukaryotic translation initiation factor 4E 0.0155242
UBXN8 UBX domain protein 8 0.0155212
MAP2K5 mitogen-activated protein kinase kinase 5 0.0155155
ZNF440 zinc finger protein 440 0.0155079
EHBP1L1 EH domain binding protein 1-like 1 0.0155012
MAGT1 magnesium transporter 1 0.015468
TET3 tet methylcytosine dioxygenase 3 0.015449
ITPRID2 ITPR interacting domain containing 2 0.0154474
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0154155
ATP5PO ATP synthase peripheral stalk subunit OSCP 0.0154065
RPL23 ribosomal protein L23 0.0153937
MTDH metadherin 0.0153708
PARP4 poly (ADP-ribose) polymerase family, member 4 0.015355
EEF2 eukaryotic translation elongation factor 2 0.0153413
AXIN1 axin 1 0.0153182
AURKAIP1 aurora kinase A interacting protein 1 0.0153155
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0152879
DSC3 desmocollin 3 0.0152839
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0152801
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.0152549
ZNF655 zinc finger protein 655 0.0152357
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0152268
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.0151935
EXOC6 exocyst complex component 6 0.0151877
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.015172
RAB10 RAB10, member RAS oncogene family 0.015165
SH3GL1 SH3-domain GRB2-like 1 0.0151386
RSL1D1 ribosomal L1 domain containing 1 0.0151102
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0150839
BMS1 BMS1 ribosome biogenesis factor 0.0150701
PPP1R21 protein phosphatase 1, regulatory subunit 21 0.0150145
DENND5B DENN/MADD domain containing 5B 0.015005
LINS1 lines homolog 1 0.0149961
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0149789
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.0149784
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0149628
TGFB1 transforming growth factor, beta 1 0.0149083
EDARADD EDAR-associated death domain 0.0148921
CAMLG calcium modulating ligand 0.0148871
WDR26 WD repeat domain 26 0.0148828
ZBTB41 zinc finger and BTB domain containing 41 0.0148719
SREK1IP1 SREK1-interacting protein 1 0.0148488
CCDC82 coiled-coil domain containing 82 0.0148434
RPL37A ribosomal protein L37a 0.0148301
NIFK nucleolar protein interacting with the FHA domain of MKI67 0.014797
MRPS15 mitochondrial ribosomal protein S15 0.0147925
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0147698
ECI1 enoyl-CoA delta isomerase 1 0.0147455
SCAF4 SR-related CTD-associated factor 4 0.0147454
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0147094
WDR33 WD repeat domain 33 0.0146853
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.0146601
RAVER1 ribonucleoprotein, PTB-binding 1 0.0146596
STAT2 signal transducer and activator of transcription 2, 113kDa 0.0146247
PTGES2 prostaglandin E synthase 2 0.0146166
DOCK2 dedicator of cytokinesis 2 0.0146128
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0146036
COG7 component of oligomeric golgi complex 7 0.0146011
PEAK1 pseudopodium-enriched atypical kinase 1 0.0145694
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 0.0145512
NAE1 NEDD8 activating enzyme E1 subunit 1 0.0145435

decreased expression

Symbol Name Standardized Value
PRKCB protein kinase C, beta -0.0912382
MED13L mediator complex subunit 13-like -0.0875389
GPC5 glypican 5 -0.0766687
TIMP1 TIMP metallopeptidase inhibitor 1 -0.068977
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0673158
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0653034
DIAPH1 diaphanous-related formin 1 -0.0542101
FHIT fragile histidine triad -0.0540371
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0537981
FAM13A family with sequence similarity 13, member A -0.0515341
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0512832
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0510322
BMP2K BMP2 inducible kinase -0.0508192
BCL2L1 BCL2-like 1 -0.0505809
TRIM27 tripartite motif containing 27 -0.0500012
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0497669
ZMYND8 zinc finger, MYND-type containing 8 -0.0476612
GLUL glutamate-ammonia ligase -0.0470627
SATB2 SATB homeobox 2 -0.0469697
SLC38A1 solute carrier family 38, member 1 -0.0469317
FAF1 Fas (TNFRSF6) associated factor 1 -0.0463505
FBXO11 F-box protein 11 -0.0462516
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0460949
FAM178B family with sequence similarity 178, member B -0.0453789
EPB41 erythrocyte membrane protein band 4.1 -0.0443651
CALU calumenin -0.0442166
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0439324
ANTXR2 anthrax toxin receptor 2 -0.0428474
USP47 ubiquitin specific peptidase 47 -0.0426005
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0418465
ADAM10 ADAM metallopeptidase domain 10 -0.041559
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0411749
PRRC2C proline-rich coiled-coil 2C -0.0411357
CANX calnexin -0.0410948
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0410294
PUS7 pseudouridylate synthase 7 (putative) -0.0397528
KDM2A lysine (K)-specific demethylase 2A -0.0388384
RELN reelin -0.0385953
BSG basigin (Ok blood group) -0.0383571
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0378112
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0377078
ZNF609 zinc finger protein 609 -0.0375667
OCIAD1 OCIA domain containing 1 -0.0375461
PCM1 pericentriolar material 1 -0.0373318
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0369691
PTK2 protein tyrosine kinase 2 -0.0365069
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -0.036484
CDK6 cyclin-dependent kinase 6 -0.0363353
SOS1 son of sevenless homolog 1 (Drosophila) -0.0361818
HEATR1 HEAT repeat containing 1 -0.0360717
LARP1 La ribonucleoprotein domain family, member 1 -0.0360351
MAST2 microtubule associated serine/threonine kinase 2 -0.0357196
CCDC57 coiled-coil domain containing 57 -0.035719
ADGRB3 adhesion G protein-coupled receptor B3 -0.0355448
XPO1 exportin 1 -0.0355057
SCARB1 scavenger receptor class B, member 1 -0.0354245
MAPK1 mitogen-activated protein kinase 1 -0.0353026
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0350664
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0349363
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0348051
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.0347992
CCAR1 cell division cycle and apoptosis regulator 1 -0.0345276
TFRC transferrin receptor -0.034482
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0340668
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0339667
ATAD2B ATPase family, AAA domain containing 2B -0.0337217
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0331867
NRDC nardilysin convertase -0.0331492
USP34 ubiquitin specific peptidase 34 -0.0330556
SGMS1 sphingomyelin synthase 1 -0.0330066
MMS22L MMS22-like, DNA repair protein -0.0327999
SIL1 SIL1 nucleotide exchange factor -0.0327872
DNA2 DNA replication helicase/nuclease 2 -0.0327241
RSRC1 arginine/serine-rich coiled-coil 1 -0.032186
RPL30 ribosomal protein L30 -0.0320542
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0318964
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0317388
TLN1 talin 1 -0.0316175
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0316058
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0311615
TPR translocated promoter region, nuclear basket protein -0.030725
SACK1A scaffolding CK1 anchoring protein A -0.0306195
NUP214 nucleoporin 214kDa -0.0305622
EXOC4 exocyst complex component 4 -0.0304532
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0304356
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.0299534
SMC4 structural maintenance of chromosomes 4 -0.0298806
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0297026
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0296282
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0295245
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.029055
PPP1R9B protein phosphatase 1, regulatory subunit 9B -0.0290043
FBXL20 F-box and leucine-rich repeat protein 20 -0.0289622
BRWD1 bromodomain and WD repeat domain containing 1 -0.0289069
SRPK1 SRSF protein kinase 1 -0.0288757
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0287785
RREB1 ras responsive element binding protein 1 -0.0284141
YARS1 tyrosyl-tRNA synthetase 1 -0.0283034
ECPAS Ecm29 proteasome adaptor and scaffold -0.0283008
CABIN1 calcineurin binding protein 1 -0.0281844
TTC3 tetratricopeptide repeat domain 3 -0.0280552
BLVRB biliverdin reductase B -0.028026
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.0279853
NCALD neurocalcin delta -0.0279831
PREPL prolyl endopeptidase-like -0.0277948
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0275673
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -0.027434
STRN3 striatin, calmodulin binding protein 3 -0.0273913
RABGAP1L RAB GTPase activating protein 1-like -0.0273814
CHD9 chromodomain helicase DNA binding protein 9 -0.0273199
GPBP1L1 GC-rich promoter binding protein 1-like 1 -0.0271973
DTNBP1 dystrobrevin binding protein 1 -0.0271106
DNAH14 dynein, axonemal, heavy chain 14 -0.0270722
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0268679
SOGA1 suppressor of glucose, autophagy associated 1 -0.0267255
FASTKD1 FAST kinase domains 1 -0.0266212
GSK3B glycogen synthase kinase 3 beta -0.0262998
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -0.0262503
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0262217
PARD3B par-3 family cell polarity regulator beta -0.0261222
MBNL1 muscleblind-like splicing regulator 1 -0.0260575
NBAS neuroblastoma amplified sequence -0.0260092
KMT2A lysine (K)-specific methyltransferase 2A -0.0259851
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0259517
KDM1B lysine (K)-specific demethylase 1B -0.0255623
REPS1 RALBP1 associated Eps domain containing 1 -0.0255544
CTSD cathepsin D -0.0254874
ACTN4 actinin, alpha 4 -0.0254825
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0253206
THADA thyroid adenoma associated -0.0252606
FNDC3B fibronectin type III domain containing 3B -0.0251142
ACBD6 acyl-CoA binding domain containing 6 -0.0250629
FAM193A family with sequence similarity 193, member A -0.0250249
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0248685
NSD1 nuclear receptor binding SET domain protein 1 -0.0248124
FDPS farnesyl diphosphate synthase -0.024801
AOPEP aminopeptidase O (putative) -0.0247459
WASF2 WAS protein family, member 2 -0.0247365
CELF1 CUGBP, Elav-like family member 1 -0.0247163
TMC6 transmembrane channel-like 6 -0.024713
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) -0.0245474
ZNF638 zinc finger protein 638 -0.0243943
SEC13 SEC13 homolog (S. cerevisiae) -0.0243745
ARID1A AT rich interactive domain 1A (SWI-like) -0.0243253
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0243006
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.0242016
GAB2 GRB2-associated binding protein 2 -0.0242008
FNBP1 formin binding protein 1 -0.0240342
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0240147
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0240095
DRC8 dynein regulatory complex subunit 8 -0.0239828
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0239002
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0238114
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0237764
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.023771
IGF2R insulin-like growth factor 2 receptor -0.0236962
TIMELESS timeless circadian clock -0.0236911
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0236438
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0235633
BICRAL BICRA like chromatin remodeling complex associated protein -0.0235577
SKIC3 SKI3 subunit of superkiller complex -0.0235373
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0235227
SUSD1 sushi domain containing 1 -0.0233317
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0233312
SFTPA2 surfactant protein A2 -0.0232997
TMEM181 transmembrane protein 181 -0.0232866
AFF1 AF4/FMR2 family, member 1 -0.0232798
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0232739
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0232448
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -0.0229796
TFCP2 transcription factor CP2 -0.0229049
RAB27A RAB27A, member RAS oncogene family -0.0228721
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -0.022822
CALN1 calneuron 1 -0.022792
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0226973
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.022686
ENOSF1 enolase superfamily member 1 -0.0226747
ZFPM2 zinc finger protein, FOG family member 2 -0.022577
SKA2 spindle and kinetochore associated complex subunit 2 -0.0225624
ZNF518A zinc finger protein 518A -0.0224645
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0224509
STIL SCL/TAL1 interrupting locus -0.0224463
ATXN2 ataxin 2 -0.0224298
RNF111 ring finger protein 111 -0.0224127
SETD5 SET domain containing 5 -0.0223672
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -0.0223187
TCERG1 transcription elongation regulator 1 -0.0222886
TTC7B tetratricopeptide repeat domain 7B -0.0222733
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0221987
AHCTF1 AT hook containing transcription factor 1 -0.0221909
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.0221885
RAB21 RAB21, member RAS oncogene family -0.0221669
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0221426
SRSF11 serine/arginine-rich splicing factor 11 -0.0220856
WRN Werner syndrome, RecQ helicase-like -0.0220443
CCM2 cerebral cavernous malformation 2 -0.0219928
XPO5 exportin 5 -0.021915
CYRIB CYFIP related Rac1 interactor B -0.0218939
NUP153 nucleoporin 153kDa -0.021893
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0218463
EIF1 eukaryotic translation initiation factor 1 -0.0218266
ELOVL5 ELOVL fatty acid elongase 5 -0.021787
HBG2 hemoglobin, gamma G -0.0217713
FAM168A family with sequence similarity 168, member A -0.0217477
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0217122
RHOH ras homolog family member H -0.0216817
CTR9 CTR9, Paf1/RNA polymerase II complex component -0.0215445
S100PBP S100P binding protein -0.0215359
SNAP29 synaptosomal-associated protein, 29kDa -0.0215029
USP6NL USP6 N-terminal like -0.0215023
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -0.0213403
ATAD3A ATPase family, AAA domain containing 3A -0.0212342
MYO18B myosin XVIIIB -0.0211611
RFWD3 ring finger and WD repeat domain 3 -0.0211225
KAT2B K(lysine) acetyltransferase 2B -0.0210921
KCTD20 potassium channel tetramerization domain containing 20 -0.0210751
ERI1 exoribonuclease 1 -0.0210261
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.021006
UBE2K ubiquitin-conjugating enzyme E2K -0.0207882
PARN poly(A)-specific ribonuclease -0.020786
UBAP2 ubiquitin associated protein 2 -0.0207282
LRRC8B leucine rich repeat containing 8 family, member B -0.0207133
PARPBP PARP1 binding protein -0.0206627
WARS1 tryptophanyl-tRNA synthetase 1 -0.0206265
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -0.0206178
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0205172
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0204894
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0204745
NT5DC1 5'-nucleotidase domain containing 1 -0.0204423
DIAPH3 diaphanous-related formin 3 -0.0204367
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0204366
SESN2 sestrin 2 -0.0203837
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0203428
PHF20 PHD finger protein 20 -0.0203094
GYS1 glycogen synthase 1 (muscle) -0.0202903
COASY CoA synthase -0.0202769
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.020216
UBTF upstream binding transcription factor, RNA polymerase I -0.0202088
LONP1 lon peptidase 1, mitochondrial -0.0201438
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0201075
EIPR1 EARP complex and GARP complex interacting protein 1 -0.0200053
BRI3BP BRI3 binding protein -0.0199418
R3HDM1 R3H domain containing 1 -0.0199416
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0199012
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -0.0196496
GATAD2A GATA zinc finger domain containing 2A -0.019636
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.0196349
RBBP8 retinoblastoma binding protein 8 -0.0196058
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0195605
PHIP pleckstrin homology domain interacting protein -0.0194389
AGPS alkylglycerone phosphate synthase -0.0194166
HSPG2 heparan sulfate proteoglycan 2 -0.0194122
TANGO6 transport and golgi organization 6 homolog (Drosophila) -0.0193909
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0193631
CTSH cathepsin H -0.0193541
MICU2 mitochondrial calcium uptake 2 -0.01928
QSER1 glutamine and serine rich 1 -0.0192671
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0192591
TOP3A topoisomerase (DNA) III alpha -0.0192322
RSBN1L round spermatid basic protein 1-like -0.0191675
ATF5 activating transcription factor 5 -0.019043
GON4L gon-4-like (C. elegans) -0.019034
SRP72 signal recognition particle 72kDa -0.0189959
NIBAN1 niban apoptosis regulator 1 -0.0189169
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0189086
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0189038
CSMD1 CUB and Sushi multiple domains 1 -0.0188719
TNIP1 TNFAIP3 interacting protein 1 -0.0188701
TMEM44 transmembrane protein 44 -0.01887
SENP5 SUMO1/sentrin specific peptidase 5 -0.0188422
TRIM56 tripartite motif containing 56 -0.0188131
UBC ubiquitin C -0.0187374
NCBP1 nuclear cap binding protein subunit 1, 80kDa -0.0186756
CLIP1 CAP-GLY domain containing linker protein 1 -0.0186749
RNF157 ring finger protein 157 -0.018659
RNFT2 ring finger protein, transmembrane 2 -0.0186546
CTBP2 C-terminal binding protein 2 -0.0186423
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0185695
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0185647
LNPEP leucyl/cystinyl aminopeptidase -0.0185488
CSPP1 centrosome and spindle pole associated protein 1 -0.0184487
MOB3A MOB kinase activator 3A -0.0184247
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0184165
TUBB tubulin, beta class I -0.0183931
IDE insulin-degrading enzyme -0.0182994
SSBP3 single stranded DNA binding protein 3 -0.018278
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.0182556
TES testin LIM domain protein -0.0182079
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0182073
ZSWIM8 zinc finger, SWIM-type containing 8 -0.018143
DMTF1 cyclin D binding myb-like transcription factor 1 -0.0181309
OSBPL6 oxysterol binding protein-like 6 -0.0181091
SENP6 SUMO1/sentrin specific peptidase 6 -0.0180864
DSG2 desmoglein 2 -0.0180678
TTC28 tetratricopeptide repeat domain 28 -0.0180517
CARM1 coactivator-associated arginine methyltransferase 1 -0.0180404
SQLE squalene epoxidase -0.0179881
RTN3 reticulon 3 -0.0179505
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.0179483
PTDSS2 phosphatidylserine synthase 2 -0.0179347
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0179254
C1ORF159 chromosome 1 open reading frame 159 -0.0179181
SPIRE1 spire-type actin nucleation factor 1 -0.0179012
TBC1D22A TBC1 domain family, member 22A -0.0178886
ATP11A ATPase, class VI, type 11A -0.0178735
ZNF148 zinc finger protein 148 -0.0178691
TP53BP1 tumor protein p53 binding protein 1 -0.0178022
RPS15 ribosomal protein S15 -0.0177936
WIPF2 WAS/WASL interacting protein family, member 2 -0.0177805
MTG2 mitochondrial ribosome-associated GTPase 2 -0.0177498
SLC10A7 solute carrier family 10, member 7 -0.0177489
CDC42 cell division cycle 42 -0.0177426
UIMC1 ubiquitin interaction motif containing 1 -0.0177343
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.017734
ZBTB20 zinc finger and BTB domain containing 20 -0.0177228
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 -0.0177175
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.0176968
TAC4 tachykinin 4 (hemokinin) -0.0176938
IWS1 IWS1 homolog (S. cerevisiae) -0.0176854
STIP1 stress-induced phosphoprotein 1 -0.0176321
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0176045
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.017602
RBM33 RNA binding motif protein 33 -0.0175771
NUP210 nucleoporin 210kDa -0.017571
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0174939
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0174287
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -0.0174119
PPARD peroxisome proliferator-activated receptor delta -0.0173977
ZNF706 zinc finger protein 706 -0.0173765
NCOA2 nuclear receptor coactivator 2 -0.0172906
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0172759
SOD1 superoxide dismutase 1, soluble -0.0172626
RABEPK Rab9 effector protein with kelch motifs -0.0172276
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.0171971
HIPK2 homeodomain interacting protein kinase 2 -0.0171559
SENP7 SUMO1/sentrin specific peptidase 7 -0.0171168
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0170991
PANK3 pantothenate kinase 3 -0.0170638
TRAPPC12 trafficking protein particle complex 12 -0.0170482
ZNF804A zinc finger protein 804A -0.0170132
FYN FYN proto-oncogene, Src family tyrosine kinase -0.0170088
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0169945
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0169738
KIF15 kinesin family member 15 -0.0169643
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0169429
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.01694
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0169281
RACK1 receptor for activated C kinase 1 -0.0169275
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0169266
PDCD11 programmed cell death 11 -0.0168793
KIAA1586 KIAA1586 -0.0168345
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -0.0168305
TMSB10 thymosin beta 10 -0.0168288
TRIM24 tripartite motif containing 24 -0.0168236
NR1H2 nuclear receptor subfamily 1, group H, member 2 -0.0168159
C21ORF58 chromosome 21 open reading frame 58 -0.0168036
YTHDC2 YTH domain containing 2 -0.0167931
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0167816
DNM1L dynamin 1-like -0.0167599
APOC1 apolipoprotein C-I -0.0167488
ERI3 ERI1 exoribonuclease family member 3 -0.0167488
TMEM87B transmembrane protein 87B -0.0167307
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0167267
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -0.0167227
CAVIN1 caveolae associated protein 1 -0.0166805
GPATCH4 G patch domain containing 4 -0.0166117
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.0165259
MCM3AP minichromosome maintenance complex component 3 associated protein -0.0165024
SERINC5 serine incorporator 5 -0.016501
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0164727
NLRP1 NLR family, pyrin domain containing 1 -0.0164719
RMDN3 regulator of microtubule dynamics 3 -0.01646
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0164522
NDC80 NDC80 kinetochore complex component -0.0164423
RPL12 ribosomal protein L12 -0.0164167
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.01636
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0162911
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0162591
HOXB3 homeobox B3 -0.0162375
MARCHF6 membrane associated ring-CH-type finger 6 -0.016215
CAPN1 calpain 1, (mu/I) large subunit -0.016208
UBE3D ubiquitin protein ligase E3D -0.0161443
SAFB scaffold attachment factor B -0.0161424
USP12 ubiquitin specific peptidase 12 -0.0161379
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 -0.0161146
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0160601
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0160278
LMBR1 limb development membrane protein 1 -0.0160019
CDCA5 cell division cycle associated 5 -0.0159951
RAB11A RAB11A, member RAS oncogene family -0.0159852
SNX3 sorting nexin 3 -0.0159624
AGFG1 ArfGAP with FG repeats 1 -0.0159514
MSI2 musashi RNA-binding protein 2 -0.0159466
BPTF bromodomain PHD finger transcription factor -0.0159394
RUBCN rubicon autophagy regulator -0.0159133
LIN9 lin-9 DREAM MuvB core complex component -0.0159035
ENKUR enkurin, TRPC channel interacting protein -0.015893
CHSY1 chondroitin sulfate synthase 1 -0.015892
WDPCP WD repeat containing planar cell polarity effector -0.0158793
DEPDC1B DEP domain containing 1B -0.0157763
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0157684
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.0157626
DDHD1 DDHD domain containing 1 -0.0157368
NAV1 neuron navigator 1 -0.0157246
EHBP1 EH domain binding protein 1 -0.0157078
ERCC8 excision repair cross-complementation group 8 -0.0156949
SLC38A6 solute carrier family 38, member 6 -0.0156792
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0156626
AGO3 argonaute RISC catalytic component 3 -0.0156256
RPS4X ribosomal protein S4, X-linked -0.0156247
DLG1 discs, large homolog 1 (Drosophila) -0.0155449
CLASP2 cytoplasmic linker associated protein 2 -0.0155442
SCAP SREBF chaperone -0.0155308
PARD6B par-6 family cell polarity regulator beta -0.0155161
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0155105
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.0154956
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0154829
PNISR PNN-interacting serine/arginine-rich protein -0.0154759
ZC3HC1 zinc finger, C3HC-type containing 1 -0.015462
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0154601
ZCCHC14 zinc finger, CCHC domain containing 14 -0.0154571
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -0.0154337
DCAF10 DDB1 and CUL4 associated factor 10 -0.0154278
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0154253
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -0.0154111
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0153901
RCOR3 REST corepressor 3 -0.0153835
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.015349
PRKD3 protein kinase D3 -0.015341
RDX radixin -0.0153148
GRAP2 GRB2-related adaptor protein 2 -0.0153051
SEPTIN9 septin 9 -0.0153033
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.0152485
BLTP3A bridge-like lipid transfer protein family member 3A -0.0152428
EVL Enah/Vasp-like -0.0152384
LRRC61 leucine rich repeat containing 61 -0.0152377
STXBP1 syntaxin binding protein 1 -0.015227
DGKH diacylglycerol kinase, eta -0.0152221
VRK1 vaccinia related kinase 1 -0.0152189
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0152008
METTL16 methyltransferase like 16 -0.0151745
RACGAP1 Rac GTPase activating protein 1 -0.0151671
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.0151602
ZNF592 zinc finger protein 592 -0.0151532
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0151383
ZFAND3 zinc finger, AN1-type domain 3 -0.0151253
COPG2 coatomer protein complex, subunit gamma 2 -0.0150979
CEP83 centrosomal protein 83kDa -0.0150866
ARHGAP11A Rho GTPase activating protein 11A -0.0150748
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0150707
FAF2 Fas associated factor family member 2 -0.0150553
CD81 CD81 molecule -0.0150517
NOL4L nucleolar protein 4-like -0.0150511
N4BP2 NEDD4 binding protein 2 -0.0150417
RNASET2 ribonuclease T2 -0.0150187
SCLT1 sodium channel and clathrin linker 1 -0.014989
ECE1 endothelin converting enzyme 1 -0.0149564
COMMD10 COMM domain containing 10 -0.0149559
WDR7 WD repeat domain 7 -0.0149494
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.0149487
WWC2 WW and C2 domain containing 2 -0.0149456
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -0.014945
USP42 ubiquitin specific peptidase 42 -0.0149417
RSF1 remodeling and spacing factor 1 -0.0149315
ZNF562 zinc finger protein 562 -0.0149121
CLIC4 chloride intracellular channel 4 -0.0148987
ADAM17 ADAM metallopeptidase domain 17 -0.0148823
SFXN1 sideroflexin 1 -0.0148789
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.0148101
BRWD3 bromodomain and WD repeat domain containing 3 -0.0148058
FAM20B family with sequence similarity 20, member B -0.014803
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.014783
USP3 ubiquitin specific peptidase 3 -0.0147777
RPL27A ribosomal protein L27a -0.0147593
H4C3 H4 clustered histone 3 -0.0147408
COPA coatomer protein complex, subunit alpha -0.0147384
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0147242
PRRC2B proline-rich coiled-coil 2B -0.0146989
CCNI cyclin I -0.0146908
RAD51 RAD51 recombinase -0.0146809
KDM5A lysine (K)-specific demethylase 5A -0.0146686
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0146615
ERCC3 excision repair cross-complementation group 3 -0.0146453
CREM cAMP responsive element modulator -0.0146422
TMCC1 transmembrane and coiled-coil domain family 1 -0.0146363
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -0.0146361
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -0.0146351
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0146204
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -0.0146134
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.014602
TTLL3 tubulin tyrosine ligase-like family member 3 -0.0145961
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0145802
FAM117B family with sequence similarity 117, member B -0.0145431
FBXO42 F-box protein 42 -0.0145372
BTBD7 BTB (POZ) domain containing 7 -0.0145295
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0144865
USP37 ubiquitin specific peptidase 37 -0.014471
KLHL23 kelch-like family member 23 -0.0144688
RAD23B RAD23 homolog B (S. cerevisiae) -0.0144661
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -0.0144584