K562_GSK-LSD1 2HCl_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 1µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK-LSD1 2HCl_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SPTBN1 spectrin, beta, non-erythrocytic 1 0.188829
VIM vimentin 0.180337
PKM pyruvate kinase, muscle 0.157005
BICD1 bicaudal D homolog 1 (Drosophila) 0.102163
MACF1 microtubule-actin crosslinking factor 1 0.100853
CFAP161 cilia and flagella associated protein 161 0.0978422
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0884859
EPB41 erythrocyte membrane protein band 4.1 0.0873336
MAML2 mastermind-like 2 (Drosophila) 0.0869709
ENO1 enolase 1, (alpha) 0.0848547
SORBS1 sorbin and SH3 domain containing 1 0.083166
TTC28 tetratricopeptide repeat domain 28 0.0784172
MYO1D myosin ID 0.0721078
BMP2K BMP2 inducible kinase 0.0713945
FAM178B family with sequence similarity 178, member B 0.0673346
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0659819
IQGAP1 IQ motif containing GTPase activating protein 1 0.0646084
AFF1 AF4/FMR2 family, member 1 0.0614506
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0611321
ZNF609 zinc finger protein 609 0.0583114
SSBP3 single stranded DNA binding protein 3 0.0577132
TIMP1 TIMP metallopeptidase inhibitor 1 0.056587
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0552195
MED13L mediator complex subunit 13-like 0.0551649
GAB2 GRB2-associated binding protein 2 0.0548667
FRYL FRY-like 0.0533636
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0521044
DAPK1 death-associated protein kinase 1 0.0512862
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.050482
NAP1L1 nucleosome assembly protein 1-like 1 0.0502627
MYO18B myosin XVIIIB 0.0502598
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0497806
FAM13A family with sequence similarity 13, member A 0.049253
DOCK2 dedicator of cytokinesis 2 0.0484474
PRKCB protein kinase C, beta 0.0481926
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0478005
KIF2A kinesin heavy chain member 2A 0.0476122
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0473821
KIAA1958 KIAA1958 0.046824
DENND4A DENN/MADD domain containing 4A 0.0464897
LOC112694756 uncharaterized LOC112694756 0.0462508
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0451265
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0445347
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.0444817
EVI5 ecotropic viral integration site 5 0.0444171
ZNF124 zinc finger protein 124 0.044383
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0442799
ANTXR2 anthrax toxin receptor 2 0.0432726
STRBP spermatid perinuclear RNA binding protein 0.0420367
FLNB filamin B, beta 0.0419674
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0415241
RPLP1 ribosomal protein, large, P1 0.0410587
SQSTM1 sequestosome 1 0.0409287
AHNAK AHNAK nucleoprotein 0.0407402
LAPTM4B lysosomal protein transmembrane 4 beta 0.0406292
PI16 peptidase inhibitor 16 0.0405751
PHGDH phosphoglycerate dehydrogenase 0.0402725
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0401971
TLE2 transducin-like enhancer of split 2 0.0401511
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0398003
AAK1 AP2 associated kinase 1 0.0395927
EXOC6 exocyst complex component 6 0.0385291
LRRC8B leucine rich repeat containing 8 family, member B 0.0379459
PCM1 pericentriolar material 1 0.0379441
BSG basigin (Ok blood group) 0.0376783
RHOH ras homolog family member H 0.037516
DMD dystrophin 0.0371957
SCARB1 scavenger receptor class B, member 1 0.0371853
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0370651
KRT18 keratin 18, type I 0.0369214
STON2 stonin 2 0.0366439
KRT19 keratin 19, type I 0.036479
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.036449
RPLP0 ribosomal protein, large, P0 0.0359429
FLT1 fms-related tyrosine kinase 1 0.0357214
TPM4 tropomyosin 4 0.0353505
RCSD1 RCSD domain containing 1 0.0346147
KMT2E lysine (K)-specific methyltransferase 2E 0.0344817
GALM galactose mutarotase (aldose 1-epimerase) 0.0343011
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0337991
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0336859
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0336604
ASPH aspartate beta-hydroxylase 0.0333997
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0333923
NFIA nuclear factor I/A 0.0326194
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0325671
BIRC6 baculoviral IAP repeat containing 6 0.032546
CD53 CD53 molecule 0.0325034
CDK13 cyclin-dependent kinase 13 0.0323122
HSPG2 heparan sulfate proteoglycan 2 0.0319548
SSBP2 single-stranded DNA binding protein 2 0.0315867
SNX25 sorting nexin 25 0.0315687
MMP12 matrix metallopeptidase 12 0.0314874
NSD2 nuclear receptor binding SET domain protein 2 0.0314397
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0314124
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.0313507
COMT catechol-O-methyltransferase 0.031168
TET1 tet methylcytosine dioxygenase 1 0.0309436
EZR ezrin 0.0308452
DENND4C DENN/MADD domain containing 4C 0.0305884
CLSTN1 calsyntenin 1 0.0304519
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0302224
FYB1 FYN binding protein 1 0.0301657
SSH1 slingshot protein phosphatase 1 0.0300649
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0299234
ADGRB3 adhesion G protein-coupled receptor B3 0.0296886
ACTG1 actin gamma 1 0.0296714
CASS4 Cas scaffolding protein family member 4 0.0296637
STX3 syntaxin 3 0.0296623
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0296392
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0293688
KLHL22 kelch-like family member 22 0.0292599
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0290255
POTEF POTE ankyrin domain family, member F 0.029017
KPNB1 karyopherin (importin) beta 1 0.0289456
KRT8 keratin 8, type II 0.0289343
WDR44 WD repeat domain 44 0.0288119
ACSL3 acyl-CoA synthetase long-chain family member 3 0.028725
FCHSD2 FCH and double SH3 domains 2 0.0280266
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0277246
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.0275281
WNT5B wingless-type MMTV integration site family, member 5B 0.0274709
TOX4 TOX high mobility group box family member 4 0.0274601
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0274537
PROCR protein C receptor, endothelial 0.0273715
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0273438
USP3 ubiquitin specific peptidase 3 0.0271407
PTPRJ protein tyrosine phosphatase, receptor type, J 0.027037
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.0270258
SORT1 sortilin 1 0.0268242
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0266978
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.0264962
FLNA filamin A, alpha 0.0264744
SNX9 sorting nexin 9 0.0264548
TRAP1 TNF receptor-associated protein 1 0.0264201
WASF2 WAS protein family, member 2 0.0263965
RPL5 ribosomal protein L5 0.0262208
ARG2 arginase 2 0.0261731
ACVR1 activin A receptor, type I 0.0261216
STMN1 stathmin 1 0.0261021
TRAPPC8 trafficking protein particle complex 8 0.0260232
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0259563
FAM78A family with sequence similarity 78, member A 0.025573
DEK DEK proto-oncogene 0.0254298
FBXL13 F-box and leucine-rich repeat protein 13 0.0252607
HMBOX1 homeobox containing 1 0.0252278
GLG1 golgi glycoprotein 1 0.0252223
SDCCAG8 serologically defined colon cancer antigen 8 0.025213
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.025138
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0249913
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0248183
CORO2A coronin, actin binding protein, 2A 0.0247846
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.0247821
EPAS1 endothelial PAS domain protein 1 0.0245522
AMBRA1 autophagy/beclin-1 regulator 1 0.0245058
PXDN peroxidasin 0.0244724
ERMP1 endoplasmic reticulum metallopeptidase 1 0.0244063
SMC4 structural maintenance of chromosomes 4 0.0243975
TUBB tubulin, beta class I 0.024369
TRNAU1AP tRNA selenocysteine 1 associated protein 1 0.0242366
GFI1B growth factor independent 1B transcription repressor 0.0241872
ZBTB20 zinc finger and BTB domain containing 20 0.0240985
BTBD9 BTB (POZ) domain containing 9 0.0240472
ANXA11 annexin A11 0.0240094
RPS3 ribosomal protein S3 0.0238959
CCNY cyclin Y 0.0238524
FAM117A family with sequence similarity 117, member A 0.0237386
GMPS guanine monphosphate synthase 0.0236388
PDIA6 protein disulfide isomerase family A, member 6 0.0235491
RHOBTB3 Rho-related BTB domain containing 3 0.02351
IL16 interleukin 16 0.0233748
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0231392
BCLAF1 BCL2-associated transcription factor 1 0.0231032
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0230369
NIBAN2 niban apoptosis regulator 2 0.0230148
DENND5A DENN/MADD domain containing 5A 0.0230007
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.0229837
BCL6 B-cell CLL/lymphoma 6 0.0229602
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.0229403
KIF1B kinesin family member 1B 0.0229176
ARID1A AT rich interactive domain 1A (SWI-like) 0.0228861
ADGRE2 adhesion G protein-coupled receptor E2 0.0228338
SND1 staphylococcal nuclease and tudor domain containing 1 0.0227382
RNF216 ring finger protein 216 0.0227136
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0226597
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0226308
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0225297
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C 0.022356
HDAC7 histone deacetylase 7 0.0221134
TMEM41A transmembrane protein 41A 0.022086
PRKCSH protein kinase C substrate 80K-H 0.0220527
CAVIN1 caveolae associated protein 1 0.0219835
GTF2IRD1 GTF2I repeat domain containing 1 0.0217794
FTL ferritin, light polypeptide 0.0215301
PARP4 poly (ADP-ribose) polymerase family, member 4 0.021484
RSL1D1 ribosomal L1 domain containing 1 0.0214405
VDAC2 voltage-dependent anion channel 2 0.0212961
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.021294
PDE7A phosphodiesterase 7A 0.0212603
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0212399
QPRT quinolinate phosphoribosyltransferase 0.0212071
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0211224
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0210916
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.0210528
MAP7 microtubule-associated protein 7 0.0210091
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0209338
ALOX5 arachidonate 5-lipoxygenase 0.0208442
SOS2 son of sevenless homolog 2 (Drosophila) 0.0208381
NCAPG non-SMC condensin I complex, subunit G 0.020777
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0207301
PLAUR plasminogen activator, urokinase receptor 0.0206946
PARP1 poly (ADP-ribose) polymerase 1 0.0206928
MPZL1 myelin protein zero-like 1 0.020627
CSMD1 CUB and Sushi multiple domains 1 0.0206109
PFN1 profilin 1 0.0205679
CSNK1A1 casein kinase 1, alpha 1 0.0205112
ACER3 alkaline ceramidase 3 0.0204904
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0202901
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.0202883
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.020218
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.0202047
KIF13B kinesin family member 13B 0.0201867
DDB1 damage-specific DNA binding protein 1, 127kDa 0.0201704
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0201473
FKBP14 FK506 binding protein 14, 22 kDa 0.0201052
MKI67 marker of proliferation Ki-67 0.0200958
MYO16 myosin XVI 0.0200588
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0200573
YPEL1 yippee-like 1 (Drosophila) 0.020049
TEC tec protein tyrosine kinase 0.0199852
EIF3B eukaryotic translation initiation factor 3, subunit B 0.0199102
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0198969
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.0197921
EPHB6 EPH receptor B6 0.0197667
MORC3 MORC family CW-type zinc finger 3 0.0197073
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0196826
FNBP1 formin binding protein 1 0.0196785
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0196339
BPTF bromodomain PHD finger transcription factor 0.019575
PDE8A phosphodiesterase 8A 0.01955
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0193786
GYS1 glycogen synthase 1 (muscle) 0.0192938
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0192802
PICALM phosphatidylinositol binding clathrin assembly protein 0.0192696
NUDCD3 NudC domain containing 3 0.0191562
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.0190747
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.0189864
ST7L suppression of tumorigenicity 7 like 0.0189199
CST3 cystatin C 0.0188076
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.018804
KMT2A lysine (K)-specific methyltransferase 2A 0.0187573
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0187202
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.0187128
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0186269
RPS6 ribosomal protein S6 0.018598
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.0185519
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0185157
ANXA7 annexin A7 0.0185037
UBXN7 UBX domain protein 7 0.0184374
ATM ATM serine/threonine kinase 0.01842
SKA2 spindle and kinetochore associated complex subunit 2 0.0184192
SIMC1 SUMO-interacting motifs containing 1 0.0183913
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0183816
TPCN1 two pore segment channel 1 0.0183514
RPS21 ribosomal protein S21 0.0183414
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.0183413
SUFU suppressor of fused homolog (Drosophila) 0.0183404
TLN1 talin 1 0.0183211
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.0182805
RUNX1 runt-related transcription factor 1 0.0182498
MAP1B microtubule-associated protein 1B 0.018246
MCM3AP minichromosome maintenance complex component 3 associated protein 0.0182389
IMMT inner membrane protein, mitochondrial 0.018226
SYNJ2 synaptojanin 2 0.0182015
CNOT2 CCR4-NOT transcription complex, subunit 2 0.0181841
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0181788
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.0181519
FN1 fibronectin 1 0.0181445
CMC4 C-x(9)-C motif containing 4 0.0180407
MYO3B myosin IIIB 0.0179435
HOXB4 homeobox B4 0.0179375
SUB1 SUB1 homolog (S. cerevisiae) 0.0178396
RNF144A ring finger protein 144A 0.0177943
GTF2I general transcription factor IIi 0.0177416
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0177234
NECTIN2 nectin cell adhesion molecule 2 0.017715
PACS1 phosphofurin acidic cluster sorting protein 1 0.0176506
APOC1 apolipoprotein C-I 0.017611
RBMX RNA binding motif protein, X-linked 0.0176011
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.0175778
PARD3B par-3 family cell polarity regulator beta 0.0175765
IQSEC2 IQ motif and Sec7 domain 2 0.0175491
PHACTR4 phosphatase and actin regulator 4 0.0175225
RAP1A RAP1A, member of RAS oncogene family 0.0174497
ACVR1B activin A receptor, type IB 0.0173512
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.0173497
ARHGAP1 Rho GTPase activating protein 1 0.017341
CHD6 chromodomain helicase DNA binding protein 6 0.0173177
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.0172858
CMIP c-Maf inducing protein 0.0172542
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0172479
OSBPL8 oxysterol binding protein-like 8 0.0172195
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.0171927
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0170664
ARHGAP12 Rho GTPase activating protein 12 0.0170384
SSB Sjogren syndrome antigen B (autoantigen La) 0.0169861
RPS11 ribosomal protein S11 0.0169773
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0168992
LUC7L LUC7-like (S. cerevisiae) 0.0168873
IL13RA1 interleukin 13 receptor, alpha 1 0.0168584
TLE5 TLE family member 5, transcriptional modulator 0.0168327
CLIC1 chloride intracellular channel 1 0.0168233
VAMP8 vesicle-associated membrane protein 8 0.0168037
TPX2 TPX2, microtubule-associated 0.0167932
VASP vasodilator-stimulated phosphoprotein 0.016786
LITAF lipopolysaccharide-induced TNF factor 0.0167718
STEAP1B STEAP family member 1B 0.0167663
ADCY7 adenylate cyclase 7 0.0167655
PRPF38B pre-mRNA processing factor 38B 0.0167385
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0166905
MCAM melanoma cell adhesion molecule 0.0166591
RNF43 ring finger protein 43 0.0165668
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0165243
PKN1 protein kinase N1 0.0164968
ANO6 anoctamin 6 0.0164955
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.0164058
IKBIP IKBKB interacting protein 0.0163901
SPATS2 spermatogenesis associated, serine-rich 2 0.0163685
SMAP1 small ArfGAP 1 0.0162925
COPA coatomer protein complex, subunit alpha 0.0162586
DOCK8 dedicator of cytokinesis 8 0.0161919
KYNU kynureninase 0.0161712
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 0.016132
HHEX hematopoietically expressed homeobox 0.0161316
CYRIB CYFIP related Rac1 interactor B 0.0161118
OXSR1 oxidative stress responsive 1 0.0160682
CHD9 chromodomain helicase DNA binding protein 9 0.01604
WDR43 WD repeat domain 43 0.0159592
VEZT vezatin, adherens junctions transmembrane protein 0.0159569
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.0159191
WWOX WW domain containing oxidoreductase 0.015896
SKIC3 SKI3 subunit of superkiller complex 0.0158796
CALR calreticulin 0.0158333
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0158288
MYO1E myosin IE 0.0158118
RAB1A RAB1A, member RAS oncogene family 0.0158031
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0157836
C6ORF89 chromosome 6 open reading frame 89 0.0157272
HELLS helicase, lymphoid-specific 0.0157171
STAT5A signal transducer and activator of transcription 5A 0.0157027
TRAK1 trafficking protein, kinesin binding 1 0.0156916
MIGA2 mitoguardin 2 0.0156171
SNX8 sorting nexin 8 0.0155236
PGPEP1 pyroglutamyl-peptidase I 0.0154946
CEP170 centrosomal protein 170kDa 0.015474
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.0154557
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0154013
RPS8 ribosomal protein S8 0.0153734
DCP2 decapping mRNA 2 0.0152957
SDAD1 SDA1 domain containing 1 0.0151105
GPATCH8 G patch domain containing 8 0.0151059
PUM3 pumilio RNA binding family member 3 0.0150804
VIRMA vir like m6A methyltransferase associated 0.0150545
ECI1 enoyl-CoA delta isomerase 1 0.0150229
CERS6 ceramide synthase 6 0.0149986
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0149722
SERF2 small EDRK-rich factor 2 0.0149326
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.0149054
PRKCE protein kinase C, epsilon 0.014856
FBXO46 F-box protein 46 0.0148451
MTMR14 myotubularin related protein 14 0.0148205
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.0148
NAV1 neuron navigator 1 0.0147786
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0147777
SIDT2 SID1 transmembrane family, member 2 0.014777
CCDC18 coiled-coil domain containing 18 0.0147682
MYO1F myosin IF 0.0147573
POC1B POC1 centriolar protein B 0.0147432
PRAME preferentially expressed antigen in melanoma 0.0146961
MRPL13 mitochondrial ribosomal protein L13 0.014673
DCLRE1C DNA cross-link repair 1C 0.0146577
CLCN5 chloride channel, voltage-sensitive 5 0.0146437
ATP11B ATPase, class VI, type 11B 0.0146318
NFE2L1 nuclear factor, erythroid 2-like 1 0.0146038
TATDN3 TatD DNase domain containing 3 0.0145923
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0145884
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0145358
LEF1 lymphoid enhancer-binding factor 1 0.0145268
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 0.0145154
TXLNA taxilin alpha 0.0144874
ATAD5 ATPase family, AAA domain containing 5 0.0144723
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.0144705
MPZ myelin protein zero 0.0144701
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0144604
MARCHF3 membrane associated ring-CH-type finger 3 0.0144572
USP8 ubiquitin specific peptidase 8 0.014437
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.0143953
HPCAL1 hippocalcin-like 1 0.0143865
PRDX1 peroxiredoxin 1 0.0143583
VAV1 vav 1 guanine nucleotide exchange factor 0.0143528
SMYD2 SET and MYND domain containing 2 0.0143253
APLP2 amyloid beta (A4) precursor-like protein 2 0.0142781
PLIN3 perilipin 3 0.0142732
CYREN cell cycle regulator of NHEJ 0.0142367
APTX aprataxin 0.0142262
PDE4D phosphodiesterase 4D, cAMP-specific 0.0141837
RAB8B RAB8B, member RAS oncogene family 0.0141469
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0141362
RNF24 ring finger protein 24 0.0141247
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0141244
IQGAP2 IQ motif containing GTPase activating protein 2 0.0141184
UBXN8 UBX domain protein 8 0.0140879
KIFAP3 kinesin-associated protein 3 0.0140879
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0140285
NBPF1 neuroblastoma breakpoint family, member 1 0.0140255
MARK4 MAP/microtubule affinity-regulating kinase 4 0.014009
SERP1 stress-associated endoplasmic reticulum protein 1 0.0139898
SLC35F5 solute carrier family 35, member F5 0.013974
OPHN1 oligophrenin 1 0.0139729
ZBTB40 zinc finger and BTB domain containing 40 0.0139668
DIAPH1 diaphanous-related formin 1 0.0139583
LTBP4 latent transforming growth factor beta binding protein 4 0.0139351
DSCAM Down syndrome cell adhesion molecule 0.0139032
IL6ST interleukin 6 signal transducer 0.0138806
BLTP2 bridge-like lipid transfer protein family member 2 0.0138727
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0138697
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.01385
DPH5 diphthamide biosynthesis 5 0.0138363
LYZ lysozyme 0.0138245
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.0138157
MIPOL1 mirror-image polydactyly 1 0.0137945
SNX27 sorting nexin family member 27 0.0137895
MRPS23 mitochondrial ribosomal protein S23 0.0137415
CD164 CD164 molecule, sialomucin 0.0137296
GRK3 G protein-coupled receptor kinase 3 0.0137133
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0137111
DICER1 dicer 1, ribonuclease type III 0.0136766
NEBL nebulette 0.0136256
BLCAP bladder cancer associated protein 0.013611
NCOR2 nuclear receptor corepressor 2 0.0136027
SOX6 SRY (sex determining region Y)-box 6 0.0135976
CCDC32 coiled-coil domain containing 32 0.0135855
ADD3 adducin 3 (gamma) 0.0135397
KIF5B kinesin family member 5B 0.0135182
CRLF3 cytokine receptor-like factor 3 0.0135157
SFXN4 sideroflexin 4 0.013504
ELMO1 engulfment and cell motility 1 0.0134946
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0134053
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0133534
TRAPPC11 trafficking protein particle complex 11 0.0133155
TRIM56 tripartite motif containing 56 0.0132782
TAC4 tachykinin 4 (hemokinin) 0.0132317
LGALS1 lectin, galactoside-binding, soluble, 1 0.0131314
TNIP1 TNFAIP3 interacting protein 1 0.0131131
BTNL9 butyrophilin-like 9 0.0131124
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0131086
LDB2 LIM domain binding 2 0.0131027
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.013073
LYAR Ly1 antibody reactive 0.0130051
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0129689
RCOR3 REST corepressor 3 0.0129523
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0129438
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0129262
ZNF394 zinc finger protein 394 0.0129204
CLASP2 cytoplasmic linker associated protein 2 0.0129013
GBP2 guanylate binding protein 2, interferon-inducible 0.0129001
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.0128974
XKR3 XK, Kell blood group complex subunit-related family, member 3 0.012895
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.0128872
ATOX1 antioxidant 1 copper chaperone 0.0128775
NACA nascent polypeptide-associated complex alpha subunit 0.012838
LIMK2 LIM domain kinase 2 0.0128319
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0128291
FCF1 FCF1 rRNA-processing protein 0.0128157
GIPR gastric inhibitory polypeptide receptor 0.0127852
RAB27A RAB27A, member RAS oncogene family 0.0127789
PEX6 peroxisomal biogenesis factor 6 0.0127599
VPS35L VPS35 endosomal protein sorting factor like 0.0127406
ZNF217 zinc finger protein 217 0.0127279
C3ORF38 chromosome 3 open reading frame 38 0.0126946
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0126822
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0126736
FBXW11 F-box and WD repeat domain containing 11 0.0126639
MCM3 minichromosome maintenance complex component 3 0.0126479
PAPOLA poly(A) polymerase alpha 0.0126469
BFAR bifunctional apoptosis regulator 0.0126422
RPL6 ribosomal protein L6 0.0126316
SNX10 sorting nexin 10 0.0125631
MEGF9 multiple EGF-like-domains 9 0.0125408
CD3D CD3d molecule, delta (CD3-TCR complex) 0.0125314
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0125295
TSG101 tumor susceptibility 101 0.0125093
RUNX2 runt-related transcription factor 2 0.0125052
CCDC50 coiled-coil domain containing 50 0.0124996
ZNF627 zinc finger protein 627 0.0124974
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.0124782
CTSB cathepsin B 0.0124616
PNPLA2 patatin-like phospholipase domain containing 2 0.012451
QSER1 glutamine and serine rich 1 0.0124323
KHSRP KH-type splicing regulatory protein 0.0124145

decreased expression

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase -0.144197
SMYD3 SET and MYND domain containing 3 -0.143975
CPED1 cadherin-like and PC-esterase domain containing 1 -0.102066
EXOC4 exocyst complex component 4 -0.0743065
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0669924
ANK1 ankyrin 1, erythrocytic -0.0633207
NUP214 nucleoporin 214kDa -0.0570056
ARL15 ADP-ribosylation factor-like 15 -0.0561308
GSE1 Gse1 coiled-coil protein -0.0540782
AIG1 androgen-induced 1 -0.0529423
ZMYND8 zinc finger, MYND-type containing 8 -0.0496835
CNKSR3 CNKSR family member 3 -0.0494495
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0491792
FAF1 Fas (TNFRSF6) associated factor 1 -0.0489179
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0485538
CEP350 centrosomal protein 350kDa -0.0468777
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0462003
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0455441
FGF13 fibroblast growth factor 13 -0.0447738
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0438324
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0437821
ACACA acetyl-CoA carboxylase alpha -0.0437046
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0436754
HBG1 hemoglobin, gamma A -0.0434279
FHIT fragile histidine triad -0.0423046
TENM1 teneurin transmembrane protein 1 -0.0414047
RHAG Rh-associated glycoprotein -0.0409652
ANKRD11 ankyrin repeat domain 11 -0.0405293
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0403009
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0396845
RNF217 ring finger protein 217 -0.0394651
RTN4 reticulon 4 -0.0393636
ANKRD17 ankyrin repeat domain 17 -0.037819
CNST consortin, connexin sorting protein -0.0369336
EIF4B eukaryotic translation initiation factor 4B -0.0359881
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.0349403
PTK2 protein tyrosine kinase 2 -0.0348189
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0346706
NMU neuromedin U -0.0338155
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0338109
TBC1D5 TBC1 domain family, member 5 -0.0337728
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0336316
CLINT1 clathrin interactor 1 -0.0333669
LARP4B La ribonucleoprotein domain family, member 4B -0.0333453
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0333201
SUSD1 sushi domain containing 1 -0.033137
CCDC88A coiled-coil domain containing 88A -0.0325973
USP15 ubiquitin specific peptidase 15 -0.0322958
RORA RAR-related orphan receptor A -0.0322731
WRN Werner syndrome, RecQ helicase-like -0.0321714
OSBPL9 oxysterol binding protein-like 9 -0.0319912
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.0319851
ATAD2B ATPase family, AAA domain containing 2B -0.0317989
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0316809
CCDC91 coiled-coil domain containing 91 -0.0316408
IPO7 importin 7 -0.0314328
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0312014
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0310466
ZEB2 zinc finger E-box binding homeobox 2 -0.0310377
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0308277
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0306879
MCU mitochondrial calcium uniporter -0.0306796
SIL1 SIL1 nucleotide exchange factor -0.0304438
THRAP3 thyroid hormone receptor associated protein 3 -0.0303819
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0303337
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0301163
MAPK1 mitogen-activated protein kinase 1 -0.0300685
UBAC1 UBA domain containing 1 -0.0298592
NBAS neuroblastoma amplified sequence -0.0295821
CHD4 chromodomain helicase DNA binding protein 4 -0.0292317
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0290024
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.028964
KIF14 kinesin family member 14 -0.0288532
TFRC transferrin receptor -0.0287751
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0287578
ZNF644 zinc finger protein 644 -0.0287425
CANX calnexin -0.028558
CALN1 calneuron 1 -0.0285274
UVRAG UV radiation resistance associated -0.0285175
MDN1 MDN1, midasin homolog (yeast) -0.0284583
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0283922
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0279127
POLK polymerase (DNA directed) kappa -0.0277869
CDC14A cell division cycle 14A -0.027694
GPC5 glypican 5 -0.0274957
TMEM135 transmembrane protein 135 -0.02749
CENPP centromere protein P -0.02745
MEIS2 Meis homeobox 2 -0.0271894
KMT2C lysine (K)-specific methyltransferase 2C -0.0271802
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0270626
NUP98 nucleoporin 98kDa -0.026975
SSR1 signal sequence receptor, alpha -0.0269744
HBG2 hemoglobin, gamma G -0.0267197
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0266086
PRELID2 PRELI domain containing 2 -0.0265333
AKAP11 A kinase (PRKA) anchor protein 11 -0.0265298
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.0264635
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0264532
RBM15 RNA binding motif protein 15 -0.0263605
NLRP1 NLR family, pyrin domain containing 1 -0.0263476
LYRM4 LYR motif containing 4 -0.0262129
GOLGA4 golgin A4 -0.0261643
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0261274
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0260283
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0259178
LEPROT leptin receptor overlapping transcript -0.0259161
MYO9B myosin IXB -0.0258085
C1ORF159 chromosome 1 open reading frame 159 -0.0256882
KIAA0319L KIAA0319-like -0.0255656
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0255207
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0254785
HIP1 huntingtin interacting protein 1 -0.0254442
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.0253823
PIGU phosphatidylinositol glycan anchor biosynthesis, class U -0.0253146
FKBP5 FK506 binding protein 5 -0.0252952
SENP5 SUMO1/sentrin specific peptidase 5 -0.0251908
FER fer (fps/fes related) tyrosine kinase -0.0251361
METTL15 methyltransferase like 15 -0.0250106
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0248482
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0247393
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0246828
CNTNAP2 contactin associated protein-like 2 -0.0245868
ARB2A ARB2 cotranscriptional regulator A -0.0245723
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0244872
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0244593
FBXO42 F-box protein 42 -0.0244511
MEF2C myocyte enhancer factor 2C -0.0243872
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.02437
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0243018
SUGP2 SURP and G patch domain containing 2 -0.024296
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.024021
MACC1 metastasis associated in colon cancer 1 -0.0240066
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0239308
ANGPT1 angiopoietin 1 -0.0237822
DNPEP aspartyl aminopeptidase -0.0236958
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0235303
CDC73 cell division cycle 73 -0.023508
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0234959
TPST2 tyrosylprotein sulfotransferase 2 -0.0234557
SOS1 son of sevenless homolog 1 (Drosophila) -0.023411
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0233284
PDCD6IP programmed cell death 6 interacting protein -0.0231886
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0231813
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0231086
NMT1 N-myristoyltransferase 1 -0.0230719
LIN9 lin-9 DREAM MuvB core complex component -0.023063
SRSF4 serine/arginine-rich splicing factor 4 -0.0230392
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.022905
GCLM glutamate-cysteine ligase, modifier subunit -0.0228133
ANKRD12 ankyrin repeat domain 12 -0.0228116
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0227697
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0225409
CKAP5 cytoskeleton associated protein 5 -0.0224829
SFSWAP splicing factor, suppressor of white-apricot family -0.0223946
CERT1 ceramide transporter 1 -0.0223649
RNF111 ring finger protein 111 -0.0223452
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.022323
ESRRB estrogen-related receptor beta -0.0221719
CDH12 cadherin 12, type 2 (N-cadherin 2) -0.022146
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0221453
ZBTB35 zinc finger and BTB domain containing 35 -0.0221443
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0220559
PROC protein C (inactivator of coagulation factors Va and VIIIa) -0.0220072
LMBR1 limb development membrane protein 1 -0.0219565
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0218822
SEPTIN6 septin 6 -0.021845
FAM222B family with sequence similarity 222, member B -0.0218243
TTC3 tetratricopeptide repeat domain 3 -0.0218152
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0217879
DCAF10 DDB1 and CUL4 associated factor 10 -0.0217215
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.0216806
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0216489
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.021585
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.0215792
DOCK11 dedicator of cytokinesis 11 -0.0214068
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0213932
ATG10 autophagy related 10 -0.0213697
MEIOB meiosis specific with OB domains -0.0213239
TNPO3 transportin 3 -0.0213198
NLK nemo-like kinase -0.0212309
MIA3 melanoma inhibitory activity family, member 3 -0.0211747
EIF5B eukaryotic translation initiation factor 5B -0.0211715
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0211083
RPL15 ribosomal protein L15 -0.0211009
STRN3 striatin, calmodulin binding protein 3 -0.021051
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.020977
MOB3B MOB kinase activator 3B -0.0209725
ZNF292 zinc finger protein 292 -0.0208618
RHBDD2 rhomboid domain containing 2 -0.0208262
KTN1 kinectin 1 (kinesin receptor) -0.0208217
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0207442
ZMYM2 zinc finger, MYM-type 2 -0.0206865
CDK12 cyclin-dependent kinase 12 -0.0206074
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0205718
ETNK1 ethanolamine kinase 1 -0.0205106
FBH1 F-box DNA helicase 1 -0.0205024
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.0204259
GDA guanine deaminase -0.0203901
BRWD1 bromodomain and WD repeat domain containing 1 -0.0202063
RPL11 ribosomal protein L11 -0.0202061
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0200862
FDPS farnesyl diphosphate synthase -0.0200445
UBE3C ubiquitin protein ligase E3C -0.0199737
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0199711
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0199474
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0199428
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0197703
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.0196904
DTNBP1 dystrobrevin binding protein 1 -0.0196357
FANCD2 Fanconi anemia, complementation group D2 -0.0196296
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0196115
LRP12 low density lipoprotein receptor-related protein 12 -0.019598
TXNIP thioredoxin interacting protein -0.0195707
AHDC1 AT hook, DNA binding motif, containing 1 -0.0195375
TNPO1 transportin 1 -0.0194278
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0194105
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0193747
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.019342
BCAP29 B-cell receptor-associated protein 29 -0.0192995
RC3H1 ring finger and CCCH-type domains 1 -0.0192097
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -0.0191436
TRIT1 tRNA isopentenyltransferase 1 -0.0191315
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0191048
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -0.0190802
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.019059
NRDC nardilysin convertase -0.0190033
MICU1 mitochondrial calcium uptake 1 -0.0189751
WAC WW domain containing adaptor with coiled-coil -0.0189583
TFCP2 transcription factor CP2 -0.0188657
CLCN3 chloride channel, voltage-sensitive 3 -0.0188283
TSC22D2 TSC22 domain family, member 2 -0.0188096
RBM33 RNA binding motif protein 33 -0.0187311
TMEM116 transmembrane protein 116 -0.0187045
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -0.0186915
RBM20 RNA binding motif protein 20 -0.0185755
QRICH1 glutamine-rich 1 -0.0185643
MPC1 mitochondrial pyruvate carrier 1 -0.018521
BCL2L1 BCL2-like 1 -0.0184714
MTFR1 mitochondrial fission regulator 1 -0.018359
ZNF846 zinc finger protein 846 -0.0183569
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0183225
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0183031
PHKB phosphorylase kinase, beta -0.0182202
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0181159
UBTF upstream binding transcription factor, RNA polymerase I -0.0180507
GPHRA golgi pH regulator A -0.0179925
MON2 MON2 homolog (S. cerevisiae) -0.0179797
JARID2 jumonji, AT rich interactive domain 2 -0.0179662
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0179408
CTSC cathepsin C -0.0179009
FAM168B family with sequence similarity 168, member B -0.017852
PTH2R parathyroid hormone 2 receptor -0.0178067
ACBD6 acyl-CoA binding domain containing 6 -0.0177713
ARHGAP18 Rho GTPase activating protein 18 -0.0177699
TACC3 transforming, acidic coiled-coil containing protein 3 -0.0177563
MTREX Mtr4 exosome RNA helicase -0.0177536
NRF1 nuclear respiratory factor 1 -0.0177534
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -0.0177509
PHIP pleckstrin homology domain interacting protein -0.0177431
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.0176764
LCORL ligand dependent nuclear receptor corepressor-like -0.0176629
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -0.0176449
HIRA histone cell cycle regulator -0.0176251
FASTKD1 FAST kinase domains 1 -0.0175212
ATXN7L1 ataxin 7-like 1 -0.0175068
NASP nuclear autoantigenic sperm protein (histone-binding) -0.0173443
RLF rearranged L-myc fusion -0.0173083
TMC6 transmembrane channel-like 6 -0.0172831
SCLT1 sodium channel and clathrin linker 1 -0.0172449
PCNX4 pecanex 4 -0.0172413
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0171165
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.017103
TRRAP transformation/transcription domain-associated protein -0.0170055
RFWD3 ring finger and WD repeat domain 3 -0.0170035
NVL nuclear VCP-like -0.0169648
SQLE squalene epoxidase -0.0169615
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0169202
INTS10 integrator complex subunit 10 -0.0169042
RPL29 ribosomal protein L29 -0.0168916
ETF1 eukaryotic translation termination factor 1 -0.0168593
PAIP2 poly(A) binding protein interacting protein 2 -0.0168439
ENOSF1 enolase superfamily member 1 -0.0168106
TRAPPC12 trafficking protein particle complex 12 -0.0167556
TMEM209 transmembrane protein 209 -0.0166868
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0166843
PRMT7 protein arginine methyltransferase 7 -0.016681
NEB nebulin -0.0166671
RBL1 retinoblastoma-like 1 -0.0166632
ELOVL5 ELOVL fatty acid elongase 5 -0.0166018
NAT10 N-acetyltransferase 10 (GCN5-related) -0.0165825
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0165748
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -0.016565
YY1AP1 YY1 associated protein 1 -0.0165588
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0165387
ZFR zinc finger RNA binding protein -0.0165366
AATF apoptosis antagonizing transcription factor -0.0164848
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0164813
BLTP1 bridge-like lipid transfer protein family member 1 -0.0164241
ADGRV1 adhesion G protein-coupled receptor V1 -0.0164241
SCFD1 sec1 family domain containing 1 -0.0164045
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.0164033
TTC7B tetratricopeptide repeat domain 7B -0.0163759
CHPT1 choline phosphotransferase 1 -0.0163045
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -0.0162642
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0162583
RHOT1 ras homolog family member T1 -0.0162381
CARS1 cysteinyl-tRNA synthetase 1 -0.0162254
PUM1 pumilio RNA-binding family member 1 -0.0161784
MLXIP MLX interacting protein -0.0161594
XPO4 exportin 4 -0.0161172
PPA2 pyrophosphatase (inorganic) 2 -0.0161145
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0160768
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0160598
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0160275
ITGB5 integrin, beta 5 -0.0160092
TENT2 terminal nucleotidyltransferase 2 -0.0159784
SETD2 SET domain containing 2 -0.0159706
SSH2 slingshot protein phosphatase 2 -0.0159094
COMMD10 COMM domain containing 10 -0.0158991
ZC3H13 zinc finger CCCH-type containing 13 -0.0158796
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 -0.0158782
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0158666
PCDH9 protocadherin 9 -0.0158095
FNDC3B fibronectin type III domain containing 3B -0.0157989
CUL1 cullin 1 -0.0157601
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -0.0157277
AHCTF1 AT hook containing transcription factor 1 -0.0157071
HBS1L HBS1-like translational GTPase -0.0156675
SENP1 SUMO1/sentrin specific peptidase 1 -0.0156533
AARS1 alanyl-tRNA synthetase 1 -0.0156487
FASN fatty acid synthase -0.0156429
ECPAS Ecm29 proteasome adaptor and scaffold -0.0155361
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0155331
ABHD18 abhydrolase domain containing 18 -0.0155226
KDM6A lysine (K)-specific demethylase 6A -0.0154776
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0154716
MYO9A myosin IXA -0.015459
NCOA3 nuclear receptor coactivator 3 -0.0154423
NEK1 NIMA-related kinase 1 -0.0154191
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.0154169
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.0154127
FRRS1 ferric-chelate reductase 1 -0.015393
MEF2A myocyte enhancer factor 2A -0.0153831
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0153607
NGLY1 N-glycanase 1 -0.0153274
CCDC57 coiled-coil domain containing 57 -0.0153067
RC3H2 ring finger and CCCH-type domains 2 -0.0153054
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.015274
ZFPM1 zinc finger protein, FOG family member 1 -0.0152679
CEP85 centrosomal protein 85kDa -0.0151867
THEM4 thioesterase superfamily member 4 -0.0151574
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0151303
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.0150926
CPEB1 cytoplasmic polyadenylation element binding protein 1 -0.0150532
BSDC1 BSD domain containing 1 -0.0150419
PPARD peroxisome proliferator-activated receptor delta -0.0150336
JAK2 Janus kinase 2 -0.015004
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.0149841
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0149809
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0149783
MARCHF6 membrane associated ring-CH-type finger 6 -0.0149724
UBE3A ubiquitin protein ligase E3A -0.0149693
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0149482
ACLY ATP citrate lyase -0.0149446
NOL10 nucleolar protein 10 -0.0149378
TBL1X transducin (beta)-like 1X-linked -0.0149087
STK40 serine/threonine kinase 40 -0.0148798
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0148503
PTCD3 pentatricopeptide repeat domain 3 -0.0148291
KMT5B lysine methyltransferase 5B -0.0148285
PIAS1 protein inhibitor of activated STAT, 1 -0.0148194
DNAH14 dynein, axonemal, heavy chain 14 -0.01479
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.014744
ZNF638 zinc finger protein 638 -0.0147189
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0147166
NUP42 nucleoporin 42 -0.014699
CHD8 chromodomain helicase DNA binding protein 8 -0.0146917
ADIPOR2 adiponectin receptor 2 -0.0146859
GIGYF2 GRB10 interacting GYF protein 2 -0.0146781
ZNF326 zinc finger protein 326 -0.0146775
PPP6C protein phosphatase 6, catalytic subunit -0.0146758
OSBP oxysterol binding protein -0.014598
PARD3 par-3 family cell polarity regulator -0.0145839
EHBP1 EH domain binding protein 1 -0.014548
METTL8 methyltransferase like 8 -0.0145458
NCAM2 neural cell adhesion molecule 2 -0.0145406
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -0.0145392
RPS4X ribosomal protein S4, X-linked -0.0145066
NCOA6 nuclear receptor coactivator 6 -0.0144922
AK1 adenylate kinase 1 -0.0144255
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -0.0144082
ATP13A2 ATPase type 13A2 -0.0144025
AFF4 AF4/FMR2 family, member 4 -0.0143938
MOB1B MOB kinase activator 1B -0.0143875
ABHD5 abhydrolase domain containing 5 -0.014353
MARCHF7 membrane associated ring-CH-type finger 7 -0.0143282
CD46 CD46 molecule, complement regulatory protein -0.0143258
GDF15 growth differentiation factor 15 -0.0143173
PPHLN1 periphilin 1 -0.0142965
TMEM63A transmembrane protein 63A -0.0142516
CLIC4 chloride intracellular channel 4 -0.0142486
FTH1 ferritin, heavy polypeptide 1 -0.0142289
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0141952
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0141318
LDHA lactate dehydrogenase A -0.0140995
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.014081
TMEM161A transmembrane protein 161A -0.0140283
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0140175
RANBP2 RAN binding protein 2 -0.01401
ODF2 outer dense fiber of sperm tails 2 -0.0140028
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0139584
PTBP2 polypyrimidine tract binding protein 2 -0.0139545
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0139531
PARVB parvin, beta -0.0139403
SCAND3 SCAN domain containing 3 -0.013922
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0139219
FAM13B family with sequence similarity 13, member B -0.0139146
HEATR5B HEAT repeat containing 5B -0.0139108
PPIA peptidylprolyl isomerase A (cyclophilin A) -0.0139105
TRIP11 thyroid hormone receptor interactor 11 -0.0138932
ERCC8 excision repair cross-complementation group 8 -0.01388
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0138776
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -0.0138716
TBCE tubulin folding cofactor E -0.0138466
TJP1 tight junction protein 1 -0.0138023
ELOVL6 ELOVL fatty acid elongase 6 -0.0138014
TMED5 transmembrane emp24 protein transport domain containing 5 -0.0137786
USP9X ubiquitin specific peptidase 9, X-linked -0.0137684
TRAPPC10 trafficking protein particle complex 10 -0.013765
PRRC2C proline-rich coiled-coil 2C -0.0137596
OCIAD1 OCIA domain containing 1 -0.0137489
DNM1L dynamin 1-like -0.0137392
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.0137328
PPME1 protein phosphatase methylesterase 1 -0.0137271
SREBF2 sterol regulatory element binding transcription factor 2 -0.0136772
CD59 CD59 molecule, complement regulatory protein -0.0136698
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0136604
PTPRB protein tyrosine phosphatase, receptor type, B -0.0136522
SRRM2 serine/arginine repetitive matrix 2 -0.0135952
GMDS GDP-mannose 4,6-dehydratase -0.0135876
SERINC3 serine incorporator 3 -0.013578
DDHD2 DDHD domain containing 2 -0.0135598
SELENOF selenoprotein F -0.0135557
UIMC1 ubiquitin interaction motif containing 1 -0.0135531
METAP1 methionyl aminopeptidase 1 -0.0135438
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0134982
KANK2 KN motif and ankyrin repeat domains 2 -0.0134842
ZHX3 zinc fingers and homeoboxes 3 -0.0134425
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.0134112
EXOC3L2 exocyst complex component 3-like 2 -0.0134022
EEF2K eukaryotic elongation factor 2 kinase -0.0133706
TBC1D15 TBC1 domain family, member 15 -0.0133512
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 -0.0133495
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0133445
TOP2B topoisomerase (DNA) II beta 180kDa -0.0133427
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0133338
SRP54 signal recognition particle 54kDa -0.0133331
ZNF526 zinc finger protein 526 -0.0133153
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -0.0132998
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.0132951
R3HDM2 R3H domain containing 2 -0.0132755
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0132525
PRR16 proline rich 16 -0.0132454
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -0.0132216
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0132198
TSPAN14 tetraspanin 14 -0.013213
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0132082
RPS12 ribosomal protein S12 -0.0132027
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0131982
MECR mitochondrial trans-2-enoyl-CoA reductase -0.0131825
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0131424
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0131276
NF1 neurofibromin 1 -0.0130961
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0130952
DCHS2 dachsous cadherin-related 2 -0.0130721
SINHCAF SIN3-HDAC complex associated factor -0.01307
CCT8 chaperonin containing TCP1, subunit 8 (theta) -0.0130585
WDR33 WD repeat domain 33 -0.0130544
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0130358
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -0.0130008
CHD1 chromodomain helicase DNA binding protein 1 -0.0129591
MAU2 MAU2 sister chromatid cohesion factor -0.0129349
KLHDC10 kelch domain containing 10 -0.0129347
THAP4 THAP domain containing 4 -0.0129279
PMPCA peptidase (mitochondrial processing) alpha -0.0129278
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0128951
RPL22 ribosomal protein L22 -0.0128947
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0128648
CR1L complement component (3b/4b) receptor 1-like -0.0128522
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0128252
PITRM1 pitrilysin metallopeptidase 1 -0.0128168
ANKLE2 ankyrin repeat and LEM domain containing 2 -0.0127939
CDC25C cell division cycle 25C -0.0127533
SRRM1 serine/arginine repetitive matrix 1 -0.012712
GMEB1 glucocorticoid modulatory element binding protein 1 -0.01271
FXR1 fragile X mental retardation, autosomal homolog 1 -0.0127051
ACTN4 actinin, alpha 4 -0.0127048
H2AZ2 H2A.Z variant histone 2 -0.0127002
PRDX5 peroxiredoxin 5 -0.0126933
EFR3A EFR3 homolog A (S. cerevisiae) -0.0126917