K562_GSK-LSD1 2HCl_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 10µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK-LSD1 2HCl_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
VIM vimentin 0.230877
SPTBN1 spectrin, beta, non-erythrocytic 1 0.168242
PKM pyruvate kinase, muscle 0.143527
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.130991
MBNL1 muscleblind-like splicing regulator 1 0.107788
PRKCB protein kinase C, beta 0.106898
ZNF609 zinc finger protein 609 0.0969019
FAM178B family with sequence similarity 178, member B 0.0950001
MAML2 mastermind-like 2 (Drosophila) 0.094876
ADGRB3 adhesion G protein-coupled receptor B3 0.0878988
MED13L mediator complex subunit 13-like 0.0810627
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0761436
BICD1 bicaudal D homolog 1 (Drosophila) 0.073134
TTC28 tetratricopeptide repeat domain 28 0.0707907
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0667091
RPLP1 ribosomal protein, large, P1 0.0661925
DOCK2 dedicator of cytokinesis 2 0.0618519
ASPH aspartate beta-hydroxylase 0.0614578
AFF1 AF4/FMR2 family, member 1 0.0595504
BSG basigin (Ok blood group) 0.0595126
ZNF124 zinc finger protein 124 0.058649
KRT8 keratin 8, type II 0.0576108
IQGAP1 IQ motif containing GTPase activating protein 1 0.0572402
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.056899
MACF1 microtubule-actin crosslinking factor 1 0.056238
CFAP161 cilia and flagella associated protein 161 0.0560039
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.0559629
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0556681
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0555783
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0554066
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0551651
JMJD1C jumonji domain containing 1C 0.0537817
HSPG2 heparan sulfate proteoglycan 2 0.0533527
AK1 adenylate kinase 1 0.0533341
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0527985
BMP2K BMP2 inducible kinase 0.0526219
ENO1 enolase 1, (alpha) 0.0518869
CCNY cyclin Y 0.0508335
NFIA nuclear factor I/A 0.049769
RHOH ras homolog family member H 0.0485088
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0484654
RCSD1 RCSD domain containing 1 0.0483281
PI16 peptidase inhibitor 16 0.0469812
SSH2 slingshot protein phosphatase 2 0.0469678
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0460617
EXOC6 exocyst complex component 6 0.0450777
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.0440318
CASS4 Cas scaffolding protein family member 4 0.0440307
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0439787
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0439191
SOX6 SRY (sex determining region Y)-box 6 0.0437706
TPM4 tropomyosin 4 0.0436914
KIAA1958 KIAA1958 0.0433172
DAPK1 death-associated protein kinase 1 0.0433135
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.043054
KIF13A kinesin family member 13A 0.0430433
SRPK2 SRSF protein kinase 2 0.0428038
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0424715
INVS inversin 0.0418527
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0412398
ANTXR2 anthrax toxin receptor 2 0.0409285
KMT2A lysine (K)-specific methyltransferase 2A 0.0403137
FYB1 FYN binding protein 1 0.0402218
GFI1B growth factor independent 1B transcription repressor 0.0388511
TBC1D5 TBC1 domain family, member 5 0.0379472
SMC4 structural maintenance of chromosomes 4 0.0366177
UBE2H ubiquitin-conjugating enzyme E2H 0.0360916
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0359211
SSBP3 single stranded DNA binding protein 3 0.0353547
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0350627
AHI1 Abelson helper integration site 1 0.0350449
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0350118
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0348159
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0345182
CENPP centromere protein P 0.0343351
STON2 stonin 2 0.0341358
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0333854
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0333782
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.033266
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0332371
ELOVL6 ELOVL fatty acid elongase 6 0.0331525
ARHGAP15 Rho GTPase activating protein 15 0.0331486
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.0323655
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0322373
OLA1 Obg-like ATPase 1 0.0320671
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.03159
ATXN2 ataxin 2 0.0310852
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0309268
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0303183
GLG1 golgi glycoprotein 1 0.0296136
AHNAK AHNAK nucleoprotein 0.0295255
CTSB cathepsin B 0.0294914
TLE2 transducin-like enhancer of split 2 0.0293028
IQGAP2 IQ motif containing GTPase activating protein 2 0.0292738
GTF2IRD1 GTF2I repeat domain containing 1 0.0290022
GAB2 GRB2-associated binding protein 2 0.028825
EZR ezrin 0.0287404
MSH3 mutS homolog 3 0.0287158
PDE7A phosphodiesterase 7A 0.0287002
RESF1 retroelement silencing factor 1 0.0283804
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0283703
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0282229
RNF216 ring finger protein 216 0.0281942
CLOCK clock circadian regulator 0.0280168
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.0279827
NAV1 neuron navigator 1 0.0278024
ANO6 anoctamin 6 0.0276434
FLNB filamin B, beta 0.0275933
NUMB numb homolog (Drosophila) 0.0274638
MEIOB meiosis specific with OB domains 0.0272147
HDAC7 histone deacetylase 7 0.0271833
NOL4L nucleolar protein 4-like 0.0271362
RPLP0 ribosomal protein, large, P0 0.0271205
DCAF7 DDB1 and CUL4 associated factor 7 0.0271188
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0269009
CLIP1 CAP-GLY domain containing linker protein 1 0.0267869
WNT5B wingless-type MMTV integration site family, member 5B 0.0266566
COMMD1 copper metabolism (Murr1) domain containing 1 0.0264821
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.0263385
CD53 CD53 molecule 0.0261618
POTEF POTE ankyrin domain family, member F 0.0260588
MAP4 microtubule-associated protein 4 0.0259386
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0258671
TIMP1 TIMP metallopeptidase inhibitor 1 0.0258071
CORO2A coronin, actin binding protein, 2A 0.0257928
MSI2 musashi RNA-binding protein 2 0.0257555
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0257536
ITSN1 intersectin 1 (SH3 domain protein) 0.0257228
KDM5B lysine (K)-specific demethylase 5B 0.0254176
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.025299
MYO16 myosin XVI 0.0252445
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0252017
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0250435
PTK2B protein tyrosine kinase 2 beta 0.0249479
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0247974
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.0247537
RIPOR3 RIPOR family member 3 0.0246977
PCED1B PC-esterase domain containing 1B 0.0246691
VCL vinculin 0.0245433
PKN1 protein kinase N1 0.0243397
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.0243043
ZMYM4 zinc finger, MYM-type 4 0.0242808
VAV1 vav 1 guanine nucleotide exchange factor 0.0242413
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0242142
GALM galactose mutarotase (aldose 1-epimerase) 0.0242026
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0241748
TAC4 tachykinin 4 (hemokinin) 0.0241174
ABHD3 abhydrolase domain containing 3 0.0239604
TMEM165 transmembrane protein 165 0.0238091
TMSB10 thymosin beta 10 0.0237853
PICALM phosphatidylinositol binding clathrin assembly protein 0.0237567
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0236474
CORO1C coronin, actin binding protein, 1C 0.0236198
ICAM1 intercellular adhesion molecule 1 0.0234549
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0230954
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.0230693
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0227952
NUCB1 nucleobindin 1 0.0227621
FAM117A family with sequence similarity 117, member A 0.0227054
RCOR1 REST corepressor 1 0.022631
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0226132
PRDX1 peroxiredoxin 1 0.0226008
H3-3B H3.3 histone B 0.0225038
ADD3 adducin 3 (gamma) 0.0224657
KDM7A lysine (K)-specific demethylase 7A 0.0223203
CCND3 cyclin D3 0.0222546
EXOC4 exocyst complex component 4 0.0221212
DNA2 DNA replication helicase/nuclease 2 0.0220514
LAPTM4B lysosomal protein transmembrane 4 beta 0.0220244
SARS2 seryl-tRNA synthetase 2, mitochondrial 0.0220126
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0219818
FYCO1 FYVE and coiled-coil domain containing 1 0.0218914
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0218081
PROCR protein C receptor, endothelial 0.0217763
CLTC clathrin, heavy chain (Hc) 0.0217653
KDM2B lysine (K)-specific demethylase 2B 0.0217557
ALOX5 arachidonate 5-lipoxygenase 0.0215412
CLIP2 CAP-GLY domain containing linker protein 2 0.0215138
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0214408
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0213398
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0212586
ANKRD26 ankyrin repeat domain 26 0.0211698
KIAA0232 KIAA0232 0.0211278
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.0209955
SGMS1 sphingomyelin synthase 1 0.0209592
RYR1 ryanodine receptor 1 (skeletal) 0.020911
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.0208543
PLIN3 perilipin 3 0.0205224
PLS1 plastin 1 0.0204316
RPS29 ribosomal protein S29 0.0204244
RBBP8 retinoblastoma binding protein 8 0.0203619
ELF4 E74-like factor 4 (ets domain transcription factor) 0.020274
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.0202695
NDC1 NDC1 transmembrane nucleoporin 0.0201559
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 0.0201341
FNBP1 formin binding protein 1 0.0200886
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0200842
DENND5A DENN/MADD domain containing 5A 0.0200598
TLK2 tousled-like kinase 2 0.0200585
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0198637
SND1 staphylococcal nuclease and tudor domain containing 1 0.019856
RPS12 ribosomal protein S12 0.0198477
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0198455
TNRC18 trinucleotide repeat containing 18 0.0198455
MYADM myeloid-associated differentiation marker 0.0197048
YME1L1 YME1-like 1 ATPase 0.0196538
SSR1 signal sequence receptor, alpha 0.0196075
STX12 syntaxin 12 0.0192687
TDRD3 tudor domain containing 3 0.0192524
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.0192346
ZMIZ1 zinc finger, MIZ-type containing 1 0.0191487
SACK1D scaffolding CK1 anchoring protein D 0.0191068
SLC35E3 solute carrier family 35, member E3 0.019099
TCF20 transcription factor 20 (AR1) 0.01906
SIMC1 SUMO-interacting motifs containing 1 0.01901
ZNF318 zinc finger protein 318 0.0189984
RNF213 ring finger protein 213 0.0189354
C4ORF36 chromosome 4 open reading frame 36 0.0189316
IL16 interleukin 16 0.018884
SP3 Sp3 transcription factor 0.0188517
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0188374
LARP1B La ribonucleoprotein domain family, member 1B 0.0187763
NIBAN1 niban apoptosis regulator 1 0.0187627
KYAT1 kynurenine aminotransferase 1 0.0187335
ETV1 ets variant 1 0.0187161
RNF130 ring finger protein 130 0.0187048
DSTYK dual serine/threonine and tyrosine protein kinase 0.0187019
MRTFA myocardin related transcription factor A 0.018684
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.0186696
NMT1 N-myristoyltransferase 1 0.0186537
UEVLD UEV and lactate/malate dehyrogenase domains 0.0186516
KTN1 kinectin 1 (kinesin receptor) 0.0186113
PRAME preferentially expressed antigen in melanoma 0.0185903
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0185822
MYO1F myosin IF 0.0185465
ACER3 alkaline ceramidase 3 0.0184855
POLH polymerase (DNA directed), eta 0.0184815
SORT1 sortilin 1 0.018407
KRT19 keratin 19, type I 0.0183658
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0182915
ACVR1B activin A receptor, type IB 0.0182525
NDE1 nudE neurodevelopment protein 1 0.0181648
PHF20 PHD finger protein 20 0.0181477
APOC1 apolipoprotein C-I 0.0181177
ZFYVE28 zinc finger, FYVE domain containing 28 0.0180085
ZNF367 zinc finger protein 367 0.0179151
LIMK2 LIM domain kinase 2 0.0178985
SLC35H1 solute carrier family 35 member H1 0.0178195
PTMS parathymosin 0.0177974
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.0177678
MPZL1 myelin protein zero-like 1 0.0177587
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0177296
ANKRD23 ankyrin repeat domain 23 0.0177064
CD164 CD164 molecule, sialomucin 0.0177037
RPL37A ribosomal protein L37a 0.0176686
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.0176639
CD44 CD44 molecule (Indian blood group) 0.0176285
DMXL1 Dmx-like 1 0.0176147
WDR59 WD repeat domain 59 0.0176094
CRYBG1 crystallin beta-gamma domain containing 1 0.0175072
NIBAN2 niban apoptosis regulator 2 0.0174523
QPRT quinolinate phosphoribosyltransferase 0.0174351
TPCN1 two pore segment channel 1 0.0174167
SENP5 SUMO1/sentrin specific peptidase 5 0.0174157
SLC71A2 solute carrier family 71 member 2 0.0173729
ATG7 autophagy related 7 0.0173659
MYO18B myosin XVIIIB 0.0172722
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0172252
CCDC6 coiled-coil domain containing 6 0.0171494
TRAF5 TNF receptor-associated factor 5 0.0171236
MYO3B myosin IIIB 0.017029
DGKD diacylglycerol kinase, delta 130kDa 0.0170038
SNX25 sorting nexin 25 0.0169701
WDR44 WD repeat domain 44 0.0169617
FOXK1 forkhead box K1 0.0169412
CMIP c-Maf inducing protein 0.0169269
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.0168801
SLMAP sarcolemma associated protein 0.0168601
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0168468
KRT18 keratin 18, type I 0.0167928
RNASET2 ribonuclease T2 0.0167542
ESRRA estrogen-related receptor alpha 0.0166929
ESYT1 extended synaptotagmin-like protein 1 0.0166835
ATAD2 ATPase family, AAA domain containing 2 0.0165816
RCC2 regulator of chromosome condensation 2 0.0164615
ADAR adenosine deaminase, RNA-specific 0.0164547
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.016417
PMEPA1 prostate transmembrane protein, androgen induced 1 0.016334
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0163208
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.0163102
KIF3B kinesin family member 3B 0.0162895
STIM1 stromal interaction molecule 1 0.0162224
SLC35G2 solute carrier family 35, member G2 0.0162179
MTDH metadherin 0.0162105
DNAH8 dynein, axonemal, heavy chain 8 0.016177
NSFL1C NSFL1 (p97) cofactor (p47) 0.0161747
ATG5 autophagy related 5 0.016152
MELK maternal embryonic leucine zipper kinase 0.0161259
ATP9B ATPase, class II, type 9B 0.0161172
SPI1 Spi-1 proto-oncogene 0.016071
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0160564
RAB2A RAB2A, member RAS oncogene family 0.01601
PTMA prothymosin, alpha 0.0159718
ZNF44 zinc finger protein 44 0.0159684
MKI67 marker of proliferation Ki-67 0.0159627
PACS1 phosphofurin acidic cluster sorting protein 1 0.0158751
ZNF326 zinc finger protein 326 0.0158722
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.0158571
CPQ carboxypeptidase Q 0.0158548
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.0157903
NFE2L2 nuclear factor, erythroid 2-like 2 0.0157606
PPCDC phosphopantothenoylcysteine decarboxylase 0.0157068
SAPCD2 suppressor APC domain containing 2 0.0156589
ZFP64 ZFP64 zinc finger protein 0.0156545
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0156426
FBXO9 F-box protein 9 0.0156351
VCP valosin containing protein 0.0156324
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.0156121
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.0155525
UNC13D unc-13 homolog D (C. elegans) 0.0155405
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.0155003
PRPF8 pre-mRNA processing factor 8 0.0154351
KIF2A kinesin heavy chain member 2A 0.0154274
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0154202
RNF38 ring finger protein 38 0.0153835
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0153745
SRSF10 serine/arginine-rich splicing factor 10 0.0153405
RPLP2 ribosomal protein, large, P2 0.0153274
FXYD5 FXYD domain containing ion transport regulator 5 0.0153257
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.015319
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.0153107
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0152908
TFF1 trefoil factor 1 0.0152531
PLK4 polo-like kinase 4 0.0152286
ZNF652 zinc finger protein 652 0.0152269
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.0152084
MPRIP myosin phosphatase Rho interacting protein 0.015181
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.0151658
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.0151469
SNX29 sorting nexin 29 0.0151466
PBRM1 polybromo 1 0.0150939
AKR1C1 aldo-keto reductase family 1, member C1 0.0150228
TMEM217 transmembrane protein 217 0.0149885
TMCC1 transmembrane and coiled-coil domain family 1 0.0149738
EPHB6 EPH receptor B6 0.0149585
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0149446
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 0.0149248
METTL2B methyltransferase like 2B 0.0149208
YIPF5 Yip1 domain family, member 5 0.0149195
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0149143
PHGDH phosphoglycerate dehydrogenase 0.0149034
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.0148971
RNF144A ring finger protein 144A 0.0148686
ZNF217 zinc finger protein 217 0.0148619
APLP2 amyloid beta (A4) precursor-like protein 2 0.0148587
NSD2 nuclear receptor binding SET domain protein 2 0.0148416
STX3 syntaxin 3 0.014831
RPL8 ribosomal protein L8 0.0148277
VEZT vezatin, adherens junctions transmembrane protein 0.0147965
SETD1B SET domain containing 1B 0.0147622
ZNF398 zinc finger protein 398 0.014693
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0146884
SWI5 SWI5 recombination repair homolog (yeast) 0.0146758
EPB41 erythrocyte membrane protein band 4.1 0.0146682
SACS sacsin molecular chaperone 0.0146583
PHACTR1 phosphatase and actin regulator 1 0.0146365
FNDC3A fibronectin type III domain containing 3A 0.014631
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.0145643
KMT2D lysine (K)-specific methyltransferase 2D 0.014549
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 0.0145414
TMEM38B transmembrane protein 38B 0.014528
TLE5 TLE family member 5, transcriptional modulator 0.0145192
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.0145116
ZDHHC6 zinc finger, DHHC-type containing 6 0.014469
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0144613
PPP6C protein phosphatase 6, catalytic subunit 0.0144579
FTO fat mass and obesity associated 0.0144539
NUDC nudC nuclear distribution protein 0.0144237
ADD1 adducin 1 (alpha) 0.014416
RAB21 RAB21, member RAS oncogene family 0.0143917
PLA2G12A phospholipase A2, group XIIA 0.0143531
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 0.0143407
ANKRD28 ankyrin repeat domain 28 0.0143347
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.0143198
CLIC1 chloride intracellular channel 1 0.0142663
SORBS1 sorbin and SH3 domain containing 1 0.014245
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0142414
WDR35 WD repeat domain 35 0.0142266
DMXL2 Dmx-like 2 0.0142154
GOLIM4 golgi integral membrane protein 4 0.0142123
XXYLT1 xyloside xylosyltransferase 1 0.0142069
TRIP12 thyroid hormone receptor interactor 12 0.0142015
SERTAD2 SERTA domain containing 2 0.0141999
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0141709
EEF2K eukaryotic elongation factor 2 kinase 0.0141658
HADH hydroxyacyl-CoA dehydrogenase 0.0141552
DCAF1 DDB1 and CUL4 associated factor 1 0.0141412
SNX9 sorting nexin 9 0.0141219
BTBD9 BTB (POZ) domain containing 9 0.0140965
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0140909
SLC39A11 solute carrier family 39, member 11 0.0140873
SPATS2 spermatogenesis associated, serine-rich 2 0.0140641
GMDS GDP-mannose 4,6-dehydratase 0.0140068
DCP2 decapping mRNA 2 0.0140025
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 0.0139726
RPS3 ribosomal protein S3 0.0139686
BMPR1A bone morphogenetic protein receptor, type IA 0.0139529
PARN poly(A)-specific ribonuclease 0.0138907
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 0.0138794
RRBP1 ribosome binding protein 1 0.0138683
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.0138524
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0138504
RAB28 RAB28, member RAS oncogene family 0.0138141
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.013786
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.0137536
GPHN gephyrin 0.0137416
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0136911
TATDN1 TatD DNase domain containing 1 0.013614
EI24 etoposide induced 2.4 0.0135811
HEATR5A HEAT repeat containing 5A 0.0135656
WDR62 WD repeat domain 62 0.0135577
LRP6 low density lipoprotein receptor-related protein 6 0.0135225
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 0.013468
DDB1 damage-specific DNA binding protein 1, 127kDa 0.0134471
RSL24D1 ribosomal L24 domain containing 1 0.0134421
TRAM2 translocation associated membrane protein 2 0.0134356
MEPCE methylphosphate capping enzyme 0.0134356
ZNF407 zinc finger protein 407 0.01343
DSCAM Down syndrome cell adhesion molecule 0.0134144
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.0134044
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.0133765
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.0133722
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0133665
SCAF11 SR-related CTD-associated factor 11 0.0133519
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0133408
SNX5 sorting nexin 5 0.0133202
PRRC2B proline-rich coiled-coil 2B 0.0133074
SMAGP small cell adhesion glycoprotein 0.0132299
TTC7A tetratricopeptide repeat domain 7A 0.0131842
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0131732
WDR33 WD repeat domain 33 0.0131592
ATAD1 ATPase family, AAA domain containing 1 0.0131294
MYLIP myosin regulatory light chain interacting protein 0.0130994
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0130827
PHB2 prohibitin 2 0.0130781
TRAPPC8 trafficking protein particle complex 8 0.0130163
TRAF3 TNF receptor-associated factor 3 0.0130039
ATAD5 ATPase family, AAA domain containing 5 0.013
SLC30A9 solute carrier family 30 (zinc transporter), member 9 0.0129924
PPP4R3A protein phosphatase 4 regulatory subunit 3A 0.0129814
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0129752
IER2 immediate early response 2 0.01297
EEF2 eukaryotic translation elongation factor 2 0.0129693
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.0129636
MCM9 minichromosome maintenance complex component 9 0.0129315
PRPF38B pre-mRNA processing factor 38B 0.0129152
SLF2 SMC5-SMC6 complex localization factor 2 0.0129088
STK24 serine/threonine kinase 24 0.0128782
ARHGAP35 Rho GTPase activating protein 35 0.0128775
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0128767
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.0128678
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0128475
LSG1 large 60S subunit nuclear export GTPase 1 0.0128113
TRIM27 tripartite motif containing 27 0.0128101
FAM78A family with sequence similarity 78, member A 0.0128092
RRP1B ribosomal RNA processing 1B 0.0127971
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.0127932
DENND5B DENN/MADD domain containing 5B 0.0127756
MAPK9 mitogen-activated protein kinase 9 0.0127662
ADSS2 adenylosuccinate synthase 2 0.012736
TPT1 tumor protein, translationally-controlled 1 0.0127317
ZNF277 zinc finger protein 277 0.0127221
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.0127196
CRPPA CDP-L-ribitol pyrophosphorylase A 0.0127156
PRR11 proline rich 11 0.0127066
ELOA elongin A 0.0127041
TRIM25 tripartite motif containing 25 0.0126978
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.0126872
CCNT1 cyclin T1 0.0126644
CCNC cyclin C 0.0126164
PARD6B par-6 family cell polarity regulator beta 0.012595
RNASEH1 ribonuclease H1 0.0125819
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0125629
SDCCAG8 serologically defined colon cancer antigen 8 0.0125347
ATP5F1E ATP synthase F1 subunit epsilon 0.0124836
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0124765
RECQL RecQ helicase-like 0.0124753
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.0124722
NBPF15 neuroblastoma breakpoint family, member 15 0.0124521
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.0124496
MOK MOK protein kinase 0.0123902
GPR107 G protein-coupled receptor 107 0.0123654
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.012348
KIFAP3 kinesin-associated protein 3 0.0123471
DSPP dentin sialophosphoprotein 0.0123372
CSNK1G2 casein kinase 1, gamma 2 0.0123359
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0123321
COG5 component of oligomeric golgi complex 5 0.0123298
BRMS1L breast cancer metastasis-suppressor 1-like 0.0123075
BCL7C B-cell CLL/lymphoma 7C 0.0122905

decreased expression

Symbol Name Standardized Value
PRKCA protein kinase C, alpha -0.106579
ARL15 ADP-ribosylation factor-like 15 -0.0937078
MUSK muscle, skeletal, receptor tyrosine kinase -0.088938
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0836095
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0725753
SMYD3 SET and MYND domain containing 3 -0.0709436
JARID2 jumonji, AT rich interactive domain 2 -0.0654575
KMT2C lysine (K)-specific methyltransferase 2C -0.0641987
FDPS farnesyl diphosphate synthase -0.0636733
RORA RAR-related orphan receptor A -0.0628875
FHIT fragile histidine triad -0.062162
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0606402
SETD5 SET domain containing 5 -0.0560599
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0542639
FGF13 fibroblast growth factor 13 -0.0521056
LDLR low density lipoprotein receptor -0.0518421
NBAS neuroblastoma amplified sequence -0.0517818
AKAP9 A kinase (PRKA) anchor protein 9 -0.0504397
RABGAP1L RAB GTPase activating protein 1-like -0.0503245
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0459974
WRN Werner syndrome, RecQ helicase-like -0.0454481
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0443353
ADGRV1 adhesion G protein-coupled receptor V1 -0.044086
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0439153
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0438171
RHAG Rh-associated glycoprotein -0.0438012
ACACA acetyl-CoA carboxylase alpha -0.0432256
AIG1 androgen-induced 1 -0.042694
NRDC nardilysin convertase -0.0424321
STRN3 striatin, calmodulin binding protein 3 -0.0423243
ANKRD17 ankyrin repeat domain 17 -0.04195
RHOBTB3 Rho-related BTB domain containing 3 -0.0419227
GPC5 glypican 5 -0.0415117
IARS1 isoleucyl-tRNA synthetase 1 -0.0411438
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0404303
TBL1X transducin (beta)-like 1X-linked -0.0398214
ARID1A AT rich interactive domain 1A (SWI-like) -0.0394967
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0393034
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0391892
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0390937
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0388892
MOB1B MOB kinase activator 1B -0.038596
SRRM2 serine/arginine repetitive matrix 2 -0.0380823
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0377052
FER fer (fps/fes related) tyrosine kinase -0.0367652
FNDC3B fibronectin type III domain containing 3B -0.0367205
CNKSR3 CNKSR family member 3 -0.0362042
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.0362016
PUM1 pumilio RNA-binding family member 1 -0.0355458
RNF217 ring finger protein 217 -0.0352597
RTN4 reticulon 4 -0.0352021
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0351415
TRIM24 tripartite motif containing 24 -0.0350455
NMU neuromedin U -0.0346158
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0345983
TGFB1 transforming growth factor, beta 1 -0.0345174
FKBP5 FK506 binding protein 5 -0.0344756
ZDHHC14 zinc finger, DHHC-type containing 14 -0.033747
FBXO42 F-box protein 42 -0.0330452
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0329976
CHD1 chromodomain helicase DNA binding protein 1 -0.0329509
CALU calumenin -0.0329265
MEIS2 Meis homeobox 2 -0.0329076
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0326516
EML4 echinoderm microtubule associated protein like 4 -0.0322225
KMT2E lysine (K)-specific methyltransferase 2E -0.032202
UBAC1 UBA domain containing 1 -0.0320762
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0320066
TCF12 transcription factor 12 -0.0318281
CNST consortin, connexin sorting protein -0.0314723
CDC27 cell division cycle 27 -0.031465
ANK1 ankyrin 1, erythrocytic -0.0311629
MBD5 methyl-CpG binding domain protein 5 -0.0310125
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.0310114
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0310011
VWDE von Willebrand factor D and EGF domains -0.0304472
PKN2 protein kinase N2 -0.0302682
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0302536
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0297193
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0295816
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0292688
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0291565
ANKRD11 ankyrin repeat domain 11 -0.0290072
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0284366
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0284183
GOLGA2 golgin A2 -0.0281519
PTGES2 prostaglandin E synthase 2 -0.0281429
FAF1 Fas (TNFRSF6) associated factor 1 -0.0278762
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0277534
TMEM135 transmembrane protein 135 -0.0276375
RLF rearranged L-myc fusion -0.0273209
NCAM2 neural cell adhesion molecule 2 -0.0270538
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0270518
STRBP spermatid perinuclear RNA binding protein -0.0269793
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0268713
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0267755
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0266819
CHD9 chromodomain helicase DNA binding protein 9 -0.026669
GCLM glutamate-cysteine ligase, modifier subunit -0.0265381
NUP107 nucleoporin 107kDa -0.0263424
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.026127
RBMX RNA binding motif protein, X-linked -0.0260062
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.025983
CALN1 calneuron 1 -0.025963
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0258778
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0256719
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0256484
ESYT2 extended synaptotagmin-like protein 2 -0.025605
ZEB2 zinc finger E-box binding homeobox 2 -0.0255999
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0255125
RANBP10 RAN binding protein 10 -0.0254962
TPX2 TPX2, microtubule-associated -0.0253904
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0253668
OSBPL9 oxysterol binding protein-like 9 -0.0253455
AMBRA1 autophagy/beclin-1 regulator 1 -0.025329
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.0253056
MARCHF3 membrane associated ring-CH-type finger 3 -0.0252594
KSR1 kinase suppressor of ras 1 -0.0252216
H2AC6 H2A clustered histone 6 -0.0251664
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0251526
FASTKD1 FAST kinase domains 1 -0.0251177
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0251153
RBBP4 retinoblastoma binding protein 4 -0.0251017
FTL ferritin, light polypeptide -0.0250599
PTBP3 polypyrimidine tract binding protein 3 -0.0250205
PPARD peroxisome proliferator-activated receptor delta -0.02494
MYO1D myosin ID -0.0247772
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0247309
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0246592
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -0.0246292
ENOSF1 enolase superfamily member 1 -0.0246107
MVD mevalonate (diphospho) decarboxylase -0.024585
ZBTB35 zinc finger and BTB domain containing 35 -0.0245147
ORC5 origin recognition complex, subunit 5 -0.0243378
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0241639
TMEM131 transmembrane protein 131 -0.0241476
YEATS2 YEATS domain containing 2 -0.0240244
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0239183
NUP153 nucleoporin 153kDa -0.0238193
DNAH14 dynein, axonemal, heavy chain 14 -0.0238063
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0236773
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.0236665
STAU1 staufen double-stranded RNA binding protein 1 -0.0235194
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0235054
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0234315
MBNL2 muscleblind-like splicing regulator 2 -0.0234087
EIF3H eukaryotic translation initiation factor 3, subunit H -0.023286
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.023197
WAC WW domain containing adaptor with coiled-coil -0.0230858
SCLT1 sodium channel and clathrin linker 1 -0.0229275
SOS1 son of sevenless homolog 1 (Drosophila) -0.0228575
TMOD1 tropomodulin 1 -0.0228387
CDC14A cell division cycle 14A -0.0228107
TPR translocated promoter region, nuclear basket protein -0.0226127
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.0226072
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0224921
OGA O-GlcNAcase -0.0223914
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0223183
FNBP4 formin binding protein 4 -0.0220712
CENPF centromere protein F, 350/400kDa -0.022061
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0219631
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0218801
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0218666
GSPT1 G1 to S phase transition 1 -0.0218243
RELN reelin -0.0217797
RBM6 RNA binding motif protein 6 -0.021672
LOC112694756 uncharaterized LOC112694756 -0.02159
SEC63 SEC63 homolog (S. cerevisiae) -0.0215661
NUP98 nucleoporin 98kDa -0.0214154
BCR breakpoint cluster region -0.0214033
ANO10 anoctamin 10 -0.0213292
ZFPM2 zinc finger protein, FOG family member 2 -0.0212724
LRP12 low density lipoprotein receptor-related protein 12 -0.0211902
SEC31A SEC31 homolog A (S. cerevisiae) -0.0210826
ARID3A AT rich interactive domain 3A (BRIGHT-like) -0.0210224
MRRF mitochondrial ribosome recycling factor -0.0209752
EXT1 exostosin glycosyltransferase 1 -0.0209052
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0209044
OSBPL3 oxysterol binding protein-like 3 -0.0208363
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0208257
CCDC138 coiled-coil domain containing 138 -0.0208238
CUX1 cut-like homeobox 1 -0.0207296
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0206733
MARCHF6 membrane associated ring-CH-type finger 6 -0.0206572
FBXL20 F-box and leucine-rich repeat protein 20 -0.0205908
FAM193A family with sequence similarity 193, member A -0.020463
WWOX WW domain containing oxidoreductase -0.0204575
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0203187
LDHA lactate dehydrogenase A -0.020138
GAN gigaxonin -0.020107
KDM4B lysine (K)-specific demethylase 4B -0.0199461
NUP214 nucleoporin 214kDa -0.0199075
ICE1 interactor of little elongation complex ELL subunit 1 -0.0199001
H2AZ2 H2A.Z variant histone 2 -0.0198507
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0198429
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0197625
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.019657
ZC3H13 zinc finger CCCH-type containing 13 -0.019654
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0195545
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -0.0193112
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.0192679
CASP8AP2 caspase 8 associated protein 2 -0.0191982
LTBP1 latent transforming growth factor beta binding protein 1 -0.0191508
PDCD6IP programmed cell death 6 interacting protein -0.0191303
H2BC15 H2B clustered histone 15 -0.0190757
SENP6 SUMO1/sentrin specific peptidase 6 -0.01905
FTH1 ferritin, heavy polypeptide 1 -0.0190234
GDA guanine deaminase -0.0190107
RPTOR regulatory associated protein of MTOR, complex 1 -0.0189021
GRB10 growth factor receptor-bound protein 10 -0.0188627
WSB1 WD repeat and SOCS box containing 1 -0.0188538
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.018831
FBXW11 F-box and WD repeat domain containing 11 -0.0186621
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0185999
SPTA1 spectrin, alpha, erythrocytic 1 -0.0185965
ZMYND8 zinc finger, MYND-type containing 8 -0.018585
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0185685
WASF2 WAS protein family, member 2 -0.0185423
USP15 ubiquitin specific peptidase 15 -0.0185142
UBE3C ubiquitin protein ligase E3C -0.0184485
PKP4 plakophilin 4 -0.01844
SPAG9 sperm associated antigen 9 -0.0183802
SFSWAP splicing factor, suppressor of white-apricot family -0.0183652
RAB10 RAB10, member RAS oncogene family -0.0183332
ECD ecdysoneless homolog (Drosophila) -0.0183119
STIP1 stress-induced phosphoprotein 1 -0.0182803
SPRED1 sprouty-related, EVH1 domain containing 1 -0.0182445
HP1BP3 heterochromatin protein 1, binding protein 3 -0.018217
PHF3 PHD finger protein 3 -0.0182164
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0181148
CDK13 cyclin-dependent kinase 13 -0.0180685
KATNA1 katanin p60 (ATPase containing) subunit A 1 -0.0180195
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.0179942
LNPK lunapark, ER junction formation factor -0.0179715
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0179274
TMEM209 transmembrane protein 209 -0.0179203
KAZN kazrin, periplakin interacting protein -0.017904
HBG1 hemoglobin, gamma A -0.0178904
HELZ helicase with zinc finger -0.0178819
MTA3 metastasis associated 1 family, member 3 -0.0178672
BLVRB biliverdin reductase B -0.0178532
CENPK centromere protein K -0.0178527
RREB1 ras responsive element binding protein 1 -0.0178248
RSRP1 arginine/serine-rich protein 1 -0.0178084
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0176029
TRA2A transformer 2 alpha homolog (Drosophila) -0.0175122
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0174271
ZNF175 zinc finger protein 175 -0.0174017
AATF apoptosis antagonizing transcription factor -0.0173912
YTHDC2 YTH domain containing 2 -0.01737
BCAP29 B-cell receptor-associated protein 29 -0.0172335
USP24 ubiquitin specific peptidase 24 -0.017225
ATXN7L1 ataxin 7-like 1 -0.0171595
NUP205 nucleoporin 205kDa -0.0171401
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -0.0171311
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0171288
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0171104
ETF1 eukaryotic translation termination factor 1 -0.0170309
SKIC3 SKI3 subunit of superkiller complex -0.0169895
MON2 MON2 homolog (S. cerevisiae) -0.0169618
SUGP2 SURP and G patch domain containing 2 -0.0168595
ZFAND3 zinc finger, AN1-type domain 3 -0.0168434
POT1 protection of telomeres 1 -0.0168017
NVL nuclear VCP-like -0.0167607
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0167351
YARS1 tyrosyl-tRNA synthetase 1 -0.0167267
CDCA2 cell division cycle associated 2 -0.0167036
ZNF146 zinc finger protein 146 -0.0167035
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0166653
HOMER1 homer scaffolding protein 1 -0.0166265
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.0166213
SETX senataxin -0.0166135
CDC45 cell division cycle 45 -0.0165469
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0165093
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0165049
CCDC18 coiled-coil domain containing 18 -0.0164517
C17ORF99 chromosome 17 open reading frame 99 -0.016444
FOXJ3 forkhead box J3 -0.0164356
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0163355
NLK nemo-like kinase -0.0163231
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.0163226
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0163208
KDM3A lysine (K)-specific demethylase 3A -0.0163046
CDC42SE2 CDC42 small effector 2 -0.0162534
C1ORF159 chromosome 1 open reading frame 159 -0.016159
SINHCAF SIN3-HDAC complex associated factor -0.0161556
SMAP1 small ArfGAP 1 -0.0160718
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0160605
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0160151
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0159812
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.01598
SRGN serglycin -0.0159713
PTBP1 polypyrimidine tract binding protein 1 -0.0159219
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0158894
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -0.0158509
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0158336
MYO9A myosin IXA -0.01583
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0158235
GATAD2B GATA zinc finger domain containing 2B -0.0158166
KATNBL1 katanin p80 subunit B-like 1 -0.0158138
DENND1A DENN/MADD domain containing 1A -0.0157914
SEC16A SEC16 homolog A (S. cerevisiae) -0.0157455
PITPNA phosphatidylinositol transfer protein, alpha -0.0157261
DCAF6 DDB1 and CUL4 associated factor 6 -0.0156973
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.015691
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0156313
KIF20B kinesin family member 20B -0.0156269
SERF2 small EDRK-rich factor 2 -0.0156131
AFG2A AFG2 AAA ATPase homolog A -0.0156079
MARCHF7 membrane associated ring-CH-type finger 7 -0.0155942
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.0155805
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0155507
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0155492
ZFPM1 zinc finger protein, FOG family member 1 -0.0155476
GRAP2 GRB2-related adaptor protein 2 -0.0155418
XPO5 exportin 5 -0.0155386
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -0.0154877
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0154867
EXOC2 exocyst complex component 2 -0.0154806
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.0154768
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0154717
SKP1 S-phase kinase-associated protein 1 -0.0154479
CCDC88A coiled-coil domain containing 88A -0.0154219
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.015397
LARS1 leucyl-tRNA synthetase 1 -0.0153264
PITRM1 pitrilysin metallopeptidase 1 -0.0153251
ERI3 ERI1 exoribonuclease family member 3 -0.0152997
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0152997
SPG11 spastic paraplegia 11 (autosomal recessive) -0.01528
TMEM181 transmembrane protein 181 -0.0152789
ZCCHC14 zinc finger, CCHC domain containing 14 -0.0152721
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0152568
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0152418
MTOR mechanistic target of rapamycin (serine/threonine kinase) -0.0152354
IDE insulin-degrading enzyme -0.0152302
TOP2B topoisomerase (DNA) II beta 180kDa -0.0152188
INTS6 integrator complex subunit 6 -0.0151689
CTBP2 C-terminal binding protein 2 -0.0151635
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0151391
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0151169
RBM33 RNA binding motif protein 33 -0.0150977
TTC3 tetratricopeptide repeat domain 3 -0.0150915
BPTF bromodomain PHD finger transcription factor -0.0150891
EIF4B eukaryotic translation initiation factor 4B -0.0150837
CLIC2 chloride intracellular channel 2 -0.0150707
STK40 serine/threonine kinase 40 -0.0150435
C6ORF89 chromosome 6 open reading frame 89 -0.0150084
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0149863
ERBIN erbb2 interacting protein -0.0149819
THEM4 thioesterase superfamily member 4 -0.0149801
MCPH1 microcephalin 1 -0.0149779
HEPH hephaestin -0.0149777
GDNF glial cell derived neurotrophic factor -0.0149242
TMEM267 transmembrane protein 267 -0.0149212
ERP44 endoplasmic reticulum protein 44 -0.014884
PLCD1 phospholipase C, delta 1 -0.0148411
ZDHHC17 zinc finger, DHHC-type containing 17 -0.0148279
SACK1A scaffolding CK1 anchoring protein A -0.0148222
STX5 syntaxin 5 -0.014757
ZC3H8 zinc finger CCCH-type containing 8 -0.0147551
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0147332
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.0146899
ATAD2B ATPase family, AAA domain containing 2B -0.0146847
ESRRB estrogen-related receptor beta -0.0146518
TXNIP thioredoxin interacting protein -0.0146434
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.0146355
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0146012
RABL6 RAB, member RAS oncogene family-like 6 -0.0145956
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -0.0145697
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 -0.0145649
OXNAD1 oxidoreductase NAD-binding domain containing 1 -0.0145455
NT5C2 5'-nucleotidase, cytosolic II -0.0145292
DENND4A DENN/MADD domain containing 4A -0.0144934
CD46 CD46 molecule, complement regulatory protein -0.0144915
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -0.0144576
TLN1 talin 1 -0.0144299
TASP1 taspase, threonine aspartase, 1 -0.014408
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.014403
RPL22 ribosomal protein L22 -0.0144005
SAMD4A sterile alpha motif domain containing 4A -0.014376
NFX1 nuclear transcription factor, X-box binding 1 -0.0143528
DCAF10 DDB1 and CUL4 associated factor 10 -0.0142759
FERMT3 fermitin family member 3 -0.0142731
NOL10 nucleolar protein 10 -0.0142704
LCLAT1 lysocardiolipin acyltransferase 1 -0.0142509
CEP83 centrosomal protein 83kDa -0.0142313
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0142129
RHBDD1 rhomboid domain containing 1 -0.0142053
FUS FUS RNA binding protein -0.0142002
R3HDM2 R3H domain containing 2 -0.0141834
ZNF638 zinc finger protein 638 -0.0141673
ATG10 autophagy related 10 -0.0141568
BCL2L1 BCL2-like 1 -0.014153
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0141455
CRLF3 cytokine receptor-like factor 3 -0.0140934
FAM13B family with sequence similarity 13, member B -0.0140488
QKI QKI, KH domain containing, RNA binding -0.0140395
NRIP1 nuclear receptor interacting protein 1 -0.0140374
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.0140332
VDAC2 voltage-dependent anion channel 2 -0.0140291
DNAAF9 dynein axonemal assembly factor 9 -0.0140152
REPS1 RALBP1 associated Eps domain containing 1 -0.0139882
NAP1L1 nucleosome assembly protein 1-like 1 -0.0139715
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0139531
CPEB1 cytoplasmic polyadenylation element binding protein 1 -0.0139524
TAOK1 TAO kinase 1 -0.013936
ELOVL5 ELOVL fatty acid elongase 5 -0.0139221
PRMT3 protein arginine methyltransferase 3 -0.0139151
TFB1M transcription factor B1, mitochondrial -0.0138959
VCF1 VCP nuclear cofactor family member 1 -0.0138785
HPCAL1 hippocalcin-like 1 -0.013842
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0138311
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0138302
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0138143
CFH complement factor H -0.0137973
RPS6 ribosomal protein S6 -0.0137895
DYNC2I1 dynein 2 intermediate chain 1 -0.013767
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -0.0137595
PTPRS protein tyrosine phosphatase, receptor type, S -0.0137581
KAT6B K(lysine) acetyltransferase 6B -0.0137468
HBG2 hemoglobin, gamma G -0.0137407
ACO2 aconitase 2, mitochondrial -0.0137119
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.013709
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0137083
BRCA1 breast cancer 1, early onset -0.0136745
MYO9B myosin IXB -0.0136397
PUM3 pumilio RNA binding family member 3 -0.0136381
YY1 YY1 transcription factor -0.0136257
STIM2 stromal interaction molecule 2 -0.0136086
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0135712
RHBDD2 rhomboid domain containing 2 -0.0135559
USO1 USO1 vesicle transport factor -0.0135461
TFR2 transferrin receptor 2 -0.0135389
SPOP speckle-type POZ protein -0.0135169
NBEAL1 neurobeachin-like 1 -0.0135056
TUBB tubulin, beta class I -0.0134916
ECSIT ECSIT signalling integrator -0.0134482
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0134382
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.0134318
RAB1A RAB1A, member RAS oncogene family -0.0134064
HDAC1 histone deacetylase 1 -0.013405
HEATR1 HEAT repeat containing 1 -0.0133858
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0133337
USP25 ubiquitin specific peptidase 25 -0.013307
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0132404
GSK3B glycogen synthase kinase 3 beta -0.0132289
SEC24D SEC24 family member D -0.0131925
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.013192
CLCN3 chloride channel, voltage-sensitive 3 -0.0131872
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.013187
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0131424
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.0131393
ARHGAP12 Rho GTPase activating protein 12 -0.0131386
BLTP1 bridge-like lipid transfer protein family member 1 -0.0131267
MTFR1 mitochondrial fission regulator 1 -0.0131034
FANCD2 Fanconi anemia, complementation group D2 -0.0131026
EVL Enah/Vasp-like -0.0130988
TSC22D2 TSC22 domain family, member 2 -0.0130816
HIPK3 homeodomain interacting protein kinase 3 -0.0130814
FBH1 F-box DNA helicase 1 -0.0130807
SRBD1 S1 RNA binding domain 1 -0.0130287
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.0130282
RBM28 RNA binding motif protein 28 -0.0130196
ZNF215 zinc finger protein 215 -0.0130034
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0130018
RPL28 ribosomal protein L28 -0.0129766
RAP1B RAP1B, member of RAS oncogene family -0.0129695
SIK2 salt-inducible kinase 2 -0.0129665
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -0.0129618
HIP1 huntingtin interacting protein 1 -0.0129543
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.012909
EIF3E eukaryotic translation initiation factor 3, subunit E -0.0128886
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.0128871
INSIG1 insulin induced gene 1 -0.0128774
S100PBP S100P binding protein -0.0128306
SLC44A5 solute carrier family 44, member 5 -0.012809
EPM2AIP1 EPM2A (laforin) interacting protein 1 -0.0127411
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0127153
GSTCD glutathione S-transferase, C-terminal domain containing -0.0127061
RPSA ribosomal protein SA -0.0126985
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0126835
PCDH9 protocadherin 9 -0.0126701
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0126639
HLTF helicase-like transcription factor -0.0126099
BTBD1 BTB (POZ) domain containing 1 -0.0125395
NNT nicotinamide nucleotide transhydrogenase -0.0124927
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0124447
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0124142
ZNF846 zinc finger protein 846 -0.0123902
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -0.0123836
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -0.0123733
MFGE8 milk fat globule-EGF factor 8 protein -0.0123581
RNF111 ring finger protein 111 -0.0123511
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.0123271
PRDX5 peroxiredoxin 5 -0.0122759
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0122547
USP33 ubiquitin specific peptidase 33 -0.0122262
PHF14 PHD finger protein 14 -0.012225
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.0122242
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -0.0122039