K562_GSK-LSD1 2HCl_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 100nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK-LSD1 2HCl_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SPTBN1 spectrin, beta, non-erythrocytic 1 0.178814
VIM vimentin 0.161023
BICD1 bicaudal D homolog 1 (Drosophila) 0.132286
EPB41 erythrocyte membrane protein band 4.1 0.102922
ADGRB3 adhesion G protein-coupled receptor B3 0.102843
ZNF124 zinc finger protein 124 0.0975347
AFF1 AF4/FMR2 family, member 1 0.0927712
BMP2K BMP2 inducible kinase 0.0925739
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0863095
FAM178B family with sequence similarity 178, member B 0.0848301
ZNF609 zinc finger protein 609 0.0840284
PKM pyruvate kinase, muscle 0.0831033
NFIA nuclear factor I/A 0.0805421
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.0769403
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0712487
FBXL13 F-box and leucine-rich repeat protein 13 0.0675854
AGO3 argonaute RISC catalytic component 3 0.0659641
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0644372
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0626906
IQGAP1 IQ motif containing GTPase activating protein 1 0.0623215
CFAP161 cilia and flagella associated protein 161 0.0621268
MYO3B myosin IIIB 0.0605101
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0602944
BSG basigin (Ok blood group) 0.0589867
SSH2 slingshot protein phosphatase 2 0.0589833
MAML2 mastermind-like 2 (Drosophila) 0.0587704
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0582882
FNBP1 formin binding protein 1 0.0579665
HSPG2 heparan sulfate proteoglycan 2 0.0574222
ANTXR2 anthrax toxin receptor 2 0.0559849
TTC28 tetratricopeptide repeat domain 28 0.0547755
SSBP3 single stranded DNA binding protein 3 0.0544643
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0543553
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0543353
COMT catechol-O-methyltransferase 0.0539546
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0531648
EXOC6 exocyst complex component 6 0.0516988
FYB1 FYN binding protein 1 0.0510855
MBNL1 muscleblind-like splicing regulator 1 0.0510679
PHACTR4 phosphatase and actin regulator 4 0.0498078
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0484303
DAPK1 death-associated protein kinase 1 0.0478953
KRT8 keratin 8, type II 0.0473862
SND1 staphylococcal nuclease and tudor domain containing 1 0.0472536
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.0448736
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0446877
AAK1 AP2 associated kinase 1 0.0446774
KIAA1958 KIAA1958 0.0441935
TNRC18 trinucleotide repeat containing 18 0.0426911
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.042402
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0423569
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0419134
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0413458
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0411909
TLE2 transducin-like enhancer of split 2 0.0408599
UBE2H ubiquitin-conjugating enzyme E2H 0.040381
EZR ezrin 0.0402531
NEMF nuclear export mediator factor 0.040186
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0394036
DOCK2 dedicator of cytokinesis 2 0.0380584
SORT1 sortilin 1 0.0372917
SNX9 sorting nexin 9 0.0363113
PRKCB protein kinase C, beta 0.036085
PICALM phosphatidylinositol binding clathrin assembly protein 0.0360467
NUMB numb homolog (Drosophila) 0.0359972
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0355509
TPM4 tropomyosin 4 0.0350963
RESF1 retroelement silencing factor 1 0.0350942
VEPH1 ventricular zone expressed PH domain-containing 1 0.0350503
TBC1D5 TBC1 domain family, member 5 0.0349991
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0347543
KIF2A kinesin heavy chain member 2A 0.0344385
UBE2K ubiquitin-conjugating enzyme E2K 0.0343924
FLNB filamin B, beta 0.0342641
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0342599
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0341838
LRRC8B leucine rich repeat containing 8 family, member B 0.0341556
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.0341068
PI16 peptidase inhibitor 16 0.0335402
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0334822
YARS1 tyrosyl-tRNA synthetase 1 0.0332551
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0331748
DIAPH3 diaphanous-related formin 3 0.0331002
CASS4 Cas scaffolding protein family member 4 0.0329182
TAOK3 TAO kinase 3 0.0324577
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0323927
PDS5A PDS5 cohesin associated factor A 0.0320696
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0315482
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0309088
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0307292
NAV1 neuron navigator 1 0.030593
INVS inversin 0.0305
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.0302106
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.030134
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0301187
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.0297163
DCAF1 DDB1 and CUL4 associated factor 1 0.0296876
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0295822
TOP6BL TOP6B like initiator of meiotic double strand breaks 0.0295183
TUT4 terminal uridylyl transferase 4 0.0295036
LOC112694756 uncharaterized LOC112694756 0.0294617
MYO18B myosin XVIIIB 0.0291908
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.0291194
RPL37A ribosomal protein L37a 0.0289983
MED13L mediator complex subunit 13-like 0.0289215
AHNAK AHNAK nucleoprotein 0.0288917
TMEM245 transmembrane protein 245 0.028888
KIAA0232 KIAA0232 0.0282908
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.0282838
KRT19 keratin 19, type I 0.0280193
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0279517
KRT18 keratin 18, type I 0.0279306
CA8 carbonic anhydrase VIII 0.0276707
CLOCK clock circadian regulator 0.0275738
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0274206
GFI1B growth factor independent 1B transcription repressor 0.0274072
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0273095
APLP2 amyloid beta (A4) precursor-like protein 2 0.0272357
OSBPL8 oxysterol binding protein-like 8 0.0271819
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.0271295
LATS1 large tumor suppressor kinase 1 0.0268866
KMT2A lysine (K)-specific methyltransferase 2A 0.0267459
RICTOR RPTOR independent companion of MTOR, complex 2 0.0265109
SORBS1 sorbin and SH3 domain containing 1 0.0265082
ATAD2 ATPase family, AAA domain containing 2 0.0262648
POLH polymerase (DNA directed), eta 0.026129
MACO1 macoilin 1 0.0259676
NCAPD2 non-SMC condensin I complex, subunit D2 0.0258913
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.0256615
MACF1 microtubule-actin crosslinking factor 1 0.0253974
XRN1 5'-3' exoribonuclease 1 0.0253283
WDPCP WD repeat containing planar cell polarity effector 0.025251
VEZT vezatin, adherens junctions transmembrane protein 0.025215
LAPTM4B lysosomal protein transmembrane 4 beta 0.025181
CDC14A cell division cycle 14A 0.02518
TM9SF3 transmembrane 9 superfamily member 3 0.0250774
SOS2 son of sevenless homolog 2 (Drosophila) 0.0249643
RHOH ras homolog family member H 0.0248694
DNAH8 dynein, axonemal, heavy chain 8 0.0248395
FAM117A family with sequence similarity 117, member A 0.024725
UBE4B ubiquitination factor E4B 0.0247042
TMSB10 thymosin beta 10 0.0247001
KDM3B lysine (K)-specific demethylase 3B 0.0246551
TEC tec protein tyrosine kinase 0.0245984
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0245316
TXK TXK tyrosine kinase 0.0244267
ANKRD26 ankyrin repeat domain 26 0.0243966
SRP72 signal recognition particle 72kDa 0.0243409
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0242655
APOE apolipoprotein E 0.0242599
POU2F1 POU class 2 homeobox 1 0.0242092
STX3 syntaxin 3 0.0241319
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0240333
TMEM165 transmembrane protein 165 0.0240213
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0240166
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.023955
TNRC6B trinucleotide repeat containing 6B 0.0239318
ATM ATM serine/threonine kinase 0.0237437
UBE2I ubiquitin-conjugating enzyme E2I 0.0236649
HMBOX1 homeobox containing 1 0.0236189
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0233111
BTBD9 BTB (POZ) domain containing 9 0.0232968
BPTF bromodomain PHD finger transcription factor 0.0232922
SNX5 sorting nexin 5 0.0232814
ACVR1 activin A receptor, type I 0.0231694
ITSN1 intersectin 1 (SH3 domain protein) 0.0231591
MAN2A1 mannosidase, alpha, class 2A, member 1 0.0230915
SCLT1 sodium channel and clathrin linker 1 0.0229823
PTGES2 prostaglandin E synthase 2 0.0229751
ADGRE5 adhesion G protein-coupled receptor E5 0.0229205
EVI5 ecotropic viral integration site 5 0.0229035
PHF21A PHD finger protein 21A 0.0228842
SIK3 SIK family kinase 3 0.0228701
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0228321
STON2 stonin 2 0.0227994
SEC13 SEC13 homolog (S. cerevisiae) 0.022666
KIF18A kinesin family member 18A 0.022665
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0224829
SLC30A6 solute carrier family 30 (zinc transporter), member 6 0.0224701
CREB1 cAMP responsive element binding protein 1 0.0224072
TRAPPC9 trafficking protein particle complex 9 0.0222075
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.0221332
WNT5B wingless-type MMTV integration site family, member 5B 0.0220469
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0217523
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0217361
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0217342
KCTD20 potassium channel tetramerization domain containing 20 0.0216288
ACTN4 actinin, alpha 4 0.021554
FBXO11 F-box protein 11 0.0214027
GARRE1 granule associated Rac and RHOG effector 1 0.0213926
MYLIP myosin regulatory light chain interacting protein 0.0213832
CLASP1 cytoplasmic linker associated protein 1 0.021162
EFL1 elongation factor like GTPase 1 0.0211011
PLIN3 perilipin 3 0.0210675
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0209718
TOX4 TOX high mobility group box family member 4 0.0209271
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0209076
KIF13B kinesin family member 13B 0.0208535
NUCB2 nucleobindin 2 0.0207777
KIF13A kinesin family member 13A 0.020684
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.0206589
MAP4 microtubule-associated protein 4 0.020653
IQGAP2 IQ motif containing GTPase activating protein 2 0.0206227
TMEM65 transmembrane protein 65 0.0206022
DENND4A DENN/MADD domain containing 4A 0.0205883
FANCC Fanconi anemia, complementation group C 0.0203351
CDC123 cell division cycle 123 0.0202612
ZNF800 zinc finger protein 800 0.0202484
SEC24A SEC24 family member A 0.0201841
FAM13A family with sequence similarity 13, member A 0.0201601
CD53 CD53 molecule 0.0201087
TUBA1B tubulin, alpha 1b 0.0200999
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0200848
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0200443
MMS22L MMS22-like, DNA repair protein 0.0199786
GCC2 GRIP and coiled-coil domain containing 2 0.0199747
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.019915
UBXN7 UBX domain protein 7 0.0198169
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0198097
RUBCN rubicon autophagy regulator 0.019694
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.01963
ZMYM4 zinc finger, MYM-type 4 0.0196041
CBFB core-binding factor, beta subunit 0.0195406
RAB6A RAB6A, member RAS oncogene family 0.019523
APOLD1 apolipoprotein L domain containing 1 0.0194899
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0.0194684
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0194585
CIZ1 CDKN1A interacting zinc finger protein 1 0.019335
WDFY2 WD repeat and FYVE domain containing 2 0.0192863
FAM120A family with sequence similarity 120A 0.0192114
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0191813
HEATR5B HEAT repeat containing 5B 0.0191348
TLE5 TLE family member 5, transcriptional modulator 0.0191343
RC3H1 ring finger and CCCH-type domains 1 0.0191247
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.019036
PARP1 poly (ADP-ribose) polymerase 1 0.0190079
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0189462
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.018889
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.0187766
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0187598
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0187471
CRY1 cryptochrome circadian clock 1 0.0186864
TBL2 transducin (beta)-like 2 0.0186839
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0186152
TM7SF3 transmembrane 7 superfamily member 3 0.0186091
HDAC4 histone deacetylase 4 0.0186082
MAML3 mastermind-like 3 (Drosophila) 0.0185724
SESN2 sestrin 2 0.0185653
IL16 interleukin 16 0.0185537
PHF20 PHD finger protein 20 0.0185461
TIMP1 TIMP metallopeptidase inhibitor 1 0.0185239
FNDC3A fibronectin type III domain containing 3A 0.0183486
RSBN1 round spermatid basic protein 1 0.0183459
DSTYK dual serine/threonine and tyrosine protein kinase 0.0183094
RNF111 ring finger protein 111 0.0182654
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0182078
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0181508
EYA3 EYA transcriptional coactivator and phosphatase 3 0.0181477
F8 coagulation factor VIII, procoagulant component 0.0181416
LARP4 La ribonucleoprotein domain family, member 4 0.0180892
GPR107 G protein-coupled receptor 107 0.0180462
CFAP97 cilia and flagella associated protein 97 0.0180304
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.018029
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0179384
MED25 mediator complex subunit 25 0.0178479
FOXP1 forkhead box P1 0.01784
ELP6 elongator acetyltransferase complex subunit 6 0.0178291
CDK13 cyclin-dependent kinase 13 0.017817
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.017811
SERINC3 serine incorporator 3 0.0178083
TMEM156 transmembrane protein 156 0.0178078
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0177975
AFTPH aftiphilin 0.0177724
TRPS1 trichorhinophalangeal syndrome I 0.0177145
CLCN5 chloride channel, voltage-sensitive 5 0.0176563
STIM1 stromal interaction molecule 1 0.017554
SEC24D SEC24 family member D 0.0175361
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0175347
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0174915
SNX4 sorting nexin 4 0.0173867
GTF2I general transcription factor IIi 0.0173319
FBXL20 F-box and leucine-rich repeat protein 20 0.0172691
RPAP2 RNA polymerase II associated protein 2 0.0172383
TRIM38 tripartite motif containing 38 0.0172049
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0171848
NIPAL3 NIPA-like domain containing 3 0.0171199
MYO1F myosin IF 0.0170904
PEAK1 pseudopodium-enriched atypical kinase 1 0.0170718
SESN1 sestrin 1 0.0170704
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0170408
RPS2 ribosomal protein S2 0.0170167
PLAGL1 pleiomorphic adenoma gene-like 1 0.016996
TRIM24 tripartite motif containing 24 0.0169722
GLE1 GLE1 RNA export mediator 0.0169687
PROCR protein C receptor, endothelial 0.0169606
VMP1 vacuole membrane protein 1 0.0169557
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0169084
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0168432
VAV1 vav 1 guanine nucleotide exchange factor 0.0168108
RNF144A ring finger protein 144A 0.0167708
SLC38A2 solute carrier family 38, member 2 0.0167615
TRAM1 translocation associated membrane protein 1 0.0167539
RAVER1 ribonucleoprotein, PTB-binding 1 0.0167209
CALCOCO2 calcium binding and coiled-coil domain 2 0.0167182
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.0167122
DGCR2 DiGeorge syndrome critical region gene 2 0.0167101
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.0166954
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0166706
ABHD3 abhydrolase domain containing 3 0.0166226
CUL3 cullin 3 0.0165983
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.0165948
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.01658
FRYL FRY-like 0.0165791
ZNF346 zinc finger protein 346 0.0165738
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.016541
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0165236
CPEB3 cytoplasmic polyadenylation element binding protein 3 0.0165057
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0165019
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0164723
RBM6 RNA binding motif protein 6 0.0164588
CCND3 cyclin D3 0.016435
SACK1A scaffolding CK1 anchoring protein A 0.0164292
GRB2 growth factor receptor-bound protein 2 0.0164194
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.0164172
TWSG1 twisted gastrulation BMP signaling modulator 1 0.0163393
NELFE negative elongation factor complex member E 0.0163347
SENP5 SUMO1/sentrin specific peptidase 5 0.0163245
DENND6A DENN/MADD domain containing 6A 0.0163228
STK40 serine/threonine kinase 40 0.0163166
USO1 USO1 vesicle transport factor 0.0162712
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.0162458
STING1 stimulator of interferon response cGAMP interactor 1 0.0162227
PCM1 pericentriolar material 1 0.0162161
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0162055
PNN pinin, desmosome associated protein 0.016197
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0161755
CORO1C coronin, actin binding protein, 1C 0.0161487
BRI3BP BRI3 binding protein 0.0161075
YPEL1 yippee-like 1 (Drosophila) 0.0160456
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 0.0160387
TUBB6 tubulin, beta 6 class V 0.0160357
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.0159748
PACS1 phosphofurin acidic cluster sorting protein 1 0.0159535
CSPP1 centrosome and spindle pole associated protein 1 0.0159385
RPS4X ribosomal protein S4, X-linked 0.0159192
CORO2A coronin, actin binding protein, 2A 0.015904
ZNF41 zinc finger protein 41 0.0158937
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0158472
FAM135A family with sequence similarity 135, member A 0.0158246
MYO16 myosin XVI 0.015779
PHGDH phosphoglycerate dehydrogenase 0.0157782
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.015763
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0157408
BAG4 BCL2-associated athanogene 4 0.0157234
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0157162
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0157137
FYCO1 FYVE and coiled-coil domain containing 1 0.0157106
RPTOR regulatory associated protein of MTOR, complex 1 0.0157097
KIFAP3 kinesin-associated protein 3 0.0156765
GYS1 glycogen synthase 1 (muscle) 0.0156671
STX5 syntaxin 5 0.0156589
OSGEP O-sialoglycoprotein endopeptidase 0.0156405
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0155954
COPZ1 coatomer protein complex, subunit zeta 1 0.0155834
TCERG1 transcription elongation regulator 1 0.0155544
RSL1D1 ribosomal L1 domain containing 1 0.0155383
CTTN cortactin 0.0154764
STXBP3 syntaxin binding protein 3 0.0154756
EPAS1 endothelial PAS domain protein 1 0.0154654
RABL6 RAB, member RAS oncogene family-like 6 0.0154145
ZYG11B zyg-11 family member B, cell cycle regulator 0.0154054
KIF21A kinesin family member 21A 0.0153985
RCSD1 RCSD domain containing 1 0.015396
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0153779
ARHGAP4 Rho GTPase activating protein 4 0.0153465
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 0.01531
CREM cAMP responsive element modulator 0.0152849
SAPCD2 suppressor APC domain containing 2 0.0152718
CDK19 cyclin-dependent kinase 19 0.0152551
METTL5 methyltransferase like 5 0.0152326
SLC35G2 solute carrier family 35, member G2 0.0152218
ANXA1 annexin A1 0.015197
TCAIM T cell activation inhibitor, mitochondrial 0.0151869
C2CD2 C2 calcium-dependent domain containing 2 0.0151778
PXDN peroxidasin 0.0151568
MZT2A mitotic spindle organizing protein 2A 0.015132
H4C8 H4 clustered histone 8 0.0151306
TET1 tet methylcytosine dioxygenase 1 0.0151217
OXSR1 oxidative stress responsive 1 0.0150575
MACROD2 MACRO domain containing 2 0.0150312
CBX5 chromobox homolog 5 0.0150149
METAP1D methionyl aminopeptidase type 1D (mitochondrial) 0.0150121
QPRT quinolinate phosphoribosyltransferase 0.0150103
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.0150034
PELI1 pellino E3 ubiquitin protein ligase 1 0.0149908
IST1 increased sodium tolerance 1 homolog (yeast) 0.014957
KLHDC10 kelch domain containing 10 0.0149314
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.014931
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0149286
SPAG9 sperm associated antigen 9 0.014922
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.0148269
LYPLA1 lysophospholipase I 0.0147961
GOLGA1 golgin A1 0.0147751
TMOD3 tropomodulin 3 (ubiquitous) 0.0147712
KIF3B kinesin family member 3B 0.0147542
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.0147222
ZMIZ1 zinc finger, MIZ-type containing 1 0.014686
H2AC6 H2A clustered histone 6 0.0146433
MORF4L1 mortality factor 4 like 1 0.0146378
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0146329
SCAI suppressor of cancer cell invasion 0.0145871
MAP2K1 mitogen-activated protein kinase kinase 1 0.0145823
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.0145754
SOCS4 suppressor of cytokine signaling 4 0.0145699
RAB10 RAB10, member RAS oncogene family 0.0145327
CCDC82 coiled-coil domain containing 82 0.0145305
NCK1 NCK adaptor protein 1 0.0144855
CDC25C cell division cycle 25C 0.0144783
TMEM59 transmembrane protein 59 0.0144755
CCNI cyclin I 0.0144741
SNX25 sorting nexin 25 0.0144677
APOC1 apolipoprotein C-I 0.0144382
KATNIP katanin interacting protein 0.0144377
KMT2E lysine (K)-specific methyltransferase 2E 0.0144325
ACER3 alkaline ceramidase 3 0.0144184
NECTIN2 nectin cell adhesion molecule 2 0.0144039
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0143433
STYXL1 serine/threonine/tyrosine interacting-like 1 0.0143424
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0143369
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.0143289
TBC1D22A TBC1 domain family, member 22A 0.014326
TES testin LIM domain protein 0.0143183
FUBP3 far upstream element (FUSE) binding protein 3 0.0143101
SEM1 SEM1 26S proteasome subunit 0.0143014
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.0142959
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0142847
SIMC1 SUMO-interacting motifs containing 1 0.0142832
CMIP c-Maf inducing protein 0.0142785
YY1 YY1 transcription factor 0.0142574
NPEPPS aminopeptidase puromycin sensitive 0.0142526
ACADVL acyl-CoA dehydrogenase, very long chain 0.0142374
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.0142241
ABI2 abl-interactor 2 0.0142164
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.014216
THRAP3 thyroid hormone receptor associated protein 3 0.0141693
USP6NL USP6 N-terminal like 0.0141649
IL1R1 interleukin 1 receptor, type I 0.014139
SAMHD1 SAM domain and HD domain 1 0.014135
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.0141304
KIFC1 kinesin family member C1 0.0140637
HLA-E major histocompatibility complex, class I, E 0.0140304
UBAP1 ubiquitin associated protein 1 0.0140104
RPL12 ribosomal protein L12 0.0140096
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0140011
DMWD dystrophia myotonica, WD repeat containing 0.0139969
FSCN1 fascin actin-bundling protein 1 0.0139664
MIA2 melanoma inhibitory activity 2 0.0139488
DCTN1 dynactin 1 0.0139382
ZSWIM6 zinc finger, SWIM-type containing 6 0.0139254
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0139125
ADD1 adducin 1 (alpha) 0.0139038
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 0.0138891
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0138712
FOXO3 forkhead box O3 0.0138649
RTN3 reticulon 3 0.0138636
SFSWAP splicing factor, suppressor of white-apricot family 0.0138614
PKN1 protein kinase N1 0.0138425
SPATS2 spermatogenesis associated, serine-rich 2 0.0138
GAB2 GRB2-associated binding protein 2 0.0137961
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.0137953
DSCAM Down syndrome cell adhesion molecule 0.013765
SATB2 SATB homeobox 2 0.0137594
COG5 component of oligomeric golgi complex 5 0.0137553
SSX3 synovial sarcoma, X breakpoint 3 0.0137482
MYO9B myosin IXB 0.013725
ORC4 origin recognition complex, subunit 4 0.0137223
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.013715
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0137101
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.0136922
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0136864
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0136784
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 0.0136774
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0136758
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0136649
ECM1 extracellular matrix protein 1 0.0136601
PPP6R1 protein phosphatase 6, regulatory subunit 1 0.0136567
SAMD4A sterile alpha motif domain containing 4A 0.0136146
NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.0136052
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 0.0135983
ORC6 origin recognition complex, subunit 6 0.0135838
COPS5 COP9 signalosome subunit 5 0.0135785
TMED9 transmembrane emp24 protein transport domain containing 9 0.0135447
CAMTA1 calmodulin binding transcription activator 1 0.0134317
FN1 fibronectin 1 0.0134089
EIF3E eukaryotic translation initiation factor 3, subunit E 0.0134
CCNY cyclin Y 0.0133922
PHACTR1 phosphatase and actin regulator 1 0.0133793
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.0133644
PA2G4 proliferation-associated 2G4, 38kDa 0.013362
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0133606

decreased expression

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase -0.169283
ARL15 ADP-ribosylation factor-like 15 -0.100142
AIG1 androgen-induced 1 -0.0825338
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0783145
FAF1 Fas (TNFRSF6) associated factor 1 -0.0770296
ZFPM2 zinc finger protein, FOG family member 2 -0.0731904
HBG2 hemoglobin, gamma G -0.0717517
RORA RAR-related orphan receptor A -0.06633
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.065654
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0648068
ZEB2 zinc finger E-box binding homeobox 2 -0.0618999
FGF13 fibroblast growth factor 13 -0.0596801
RHAG Rh-associated glycoprotein -0.0578726
PTK2 protein tyrosine kinase 2 -0.0572614
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0534075
ADGRV1 adhesion G protein-coupled receptor V1 -0.0526508
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0523132
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0517762
USP15 ubiquitin specific peptidase 15 -0.0514321
SRRM2 serine/arginine repetitive matrix 2 -0.0510823
HBG1 hemoglobin, gamma A -0.0458897
RLF rearranged L-myc fusion -0.0456048
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0441412
GATAD2A GATA zinc finger domain containing 2A -0.0434624
FHIT fragile histidine triad -0.0431574
FLNA filamin A, alpha -0.0424469
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0417424
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0409395
SRPK2 SRSF protein kinase 2 -0.0409003
CHD9 chromodomain helicase DNA binding protein 9 -0.0407792
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0402481
NUP153 nucleoporin 153kDa -0.0384866
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0382913
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0379425
CUX1 cut-like homeobox 1 -0.0378673
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0375815
WRN Werner syndrome, RecQ helicase-like -0.0373713
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.037205
GSE1 Gse1 coiled-coil protein -0.0369665
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0368874
BIRC6 baculoviral IAP repeat containing 6 -0.0367712
NMU neuromedin U -0.0365174
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0361683
ECPAS Ecm29 proteasome adaptor and scaffold -0.0358899
KMT2C lysine (K)-specific methyltransferase 2C -0.0357191
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0353881
DIAPH1 diaphanous-related formin 1 -0.034943
PPARD peroxisome proliferator-activated receptor delta -0.0345715
ZMYND8 zinc finger, MYND-type containing 8 -0.0345241
PCDH9 protocadherin 9 -0.033516
JARID2 jumonji, AT rich interactive domain 2 -0.0332572
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0332532
SOS1 son of sevenless homolog 1 (Drosophila) -0.0330983
INO80 INO80 complex subunit -0.032854
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.032697
TBL1X transducin (beta)-like 1X-linked -0.0325527
WAC WW domain containing adaptor with coiled-coil -0.0324663
RPL15 ribosomal protein L15 -0.0322898
CTBP2 C-terminal binding protein 2 -0.0321968
RTN4 reticulon 4 -0.0320972
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.032071
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0319396
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0315664
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0313318
STAU1 staufen double-stranded RNA binding protein 1 -0.0313192
RSRC1 arginine/serine-rich coiled-coil 1 -0.030854
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.030747
STRN3 striatin, calmodulin binding protein 3 -0.0307077
MEIS2 Meis homeobox 2 -0.0303189
FDPS farnesyl diphosphate synthase -0.0303097
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.0301193
PTPRA protein tyrosine phosphatase, receptor type, A -0.0301039
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.0301011
TFRC transferrin receptor -0.0299377
SFTPA2 surfactant protein A2 -0.0298674
TRA2A transformer 2 alpha homolog (Drosophila) -0.0297002
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0296818
AKAP9 A kinase (PRKA) anchor protein 9 -0.0296495
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0291287
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0287524
NUP210 nucleoporin 210kDa -0.0286602
DNAH14 dynein, axonemal, heavy chain 14 -0.0285986
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0284767
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0280439
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0280094
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0278641
NAP1L4 nucleosome assembly protein 1-like 4 -0.0278022
CAB39 calcium binding protein 39 -0.0275536
BLVRB biliverdin reductase B -0.0274508
LARP1 La ribonucleoprotein domain family, member 1 -0.0273871
PKP4 plakophilin 4 -0.027118
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0270959
RPLP2 ribosomal protein, large, P2 -0.0268229
PUS7 pseudouridylate synthase 7 (putative) -0.026605
FTL ferritin, light polypeptide -0.0265252
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0265203
CNST consortin, connexin sorting protein -0.0262287
RPL18 ribosomal protein L18 -0.0261252
CHD4 chromodomain helicase DNA binding protein 4 -0.026117
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0258763
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0258653
DEAF1 DEAF1 transcription factor -0.0258589
MYO1D myosin ID -0.0257936
MKI67 marker of proliferation Ki-67 -0.0256867
CHD1 chromodomain helicase DNA binding protein 1 -0.0256452
FASN fatty acid synthase -0.025583
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0255472
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0254304
TCF12 transcription factor 12 -0.0253321
TPR translocated promoter region, nuclear basket protein -0.0252905
RPS5 ribosomal protein S5 -0.0252138
LTBP1 latent transforming growth factor beta binding protein 1 -0.0251698
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.025092
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0250451
CNKSR3 CNKSR family member 3 -0.0249576
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.0248484
ELOVL5 ELOVL fatty acid elongase 5 -0.0248373
VWDE von Willebrand factor D and EGF domains -0.0244234
TRRAP transformation/transcription domain-associated protein -0.0243899
TCF25 transcription factor 25 (basic helix-loop-helix) -0.0243669
PKN2 protein kinase N2 -0.0243268
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -0.0241401
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.024085
MFGE8 milk fat globule-EGF factor 8 protein -0.0240686
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0239267
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0237819
GSK3B glycogen synthase kinase 3 beta -0.0237723
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0237205
AKAP11 A kinase (PRKA) anchor protein 11 -0.023716
CTSD cathepsin D -0.0236123
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.0235907
NUP107 nucleoporin 107kDa -0.0235869
PUM1 pumilio RNA-binding family member 1 -0.0234525
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0233576
TMC6 transmembrane channel-like 6 -0.0228807
TUSC3 tumor suppressor candidate 3 -0.0228243
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0224803
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0223953
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0222886
TNPO3 transportin 3 -0.0222549
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0222296
STRIP2 striatin interacting protein 2 -0.0221807
JMJD1C jumonji domain containing 1C -0.0221667
GMDS GDP-mannose 4,6-dehydratase -0.0221034
ACBD6 acyl-CoA binding domain containing 6 -0.0220979
PDE4DIP phosphodiesterase 4D interacting protein -0.0220954
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0219919
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -0.0219193
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0218889
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0218812
RNF217 ring finger protein 217 -0.0218279
CAMKMT calmodulin-lysine N-methyltransferase -0.0217346
LYRM4 LYR motif containing 4 -0.0216814
ANK1 ankyrin 1, erythrocytic -0.0216406
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0216288
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -0.0214496
MAP1B microtubule-associated protein 1B -0.0214018
CLASP2 cytoplasmic linker associated protein 2 -0.0213638
CRTC3 CREB regulated transcription coactivator 3 -0.0211724
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.0211011
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0211002
NRF1 nuclear respiratory factor 1 -0.0209728
JAK2 Janus kinase 2 -0.020925
SRSF4 serine/arginine-rich splicing factor 4 -0.0209116
SMYD3 SET and MYND domain containing 3 -0.0208811
SFXN5 sideroflexin 5 -0.0208332
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0208314
TBC1D32 TBC1 domain family, member 32 -0.0208101
KIF18B kinesin family member 18B -0.0206697
ARHGAP6 Rho GTPase activating protein 6 -0.0205897
CLTCL1 clathrin, heavy chain-like 1 -0.0204975
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0204352
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0204267
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0203791
KDM4B lysine (K)-specific demethylase 4B -0.0202866
RPS9 ribosomal protein S9 -0.0202605
USP48 ubiquitin specific peptidase 48 -0.0201615
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -0.0201314
TBCE tubulin folding cofactor E -0.0201075
YAF2 YY1 associated factor 2 -0.0200451
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0200373
CRLF3 cytokine receptor-like factor 3 -0.020011
ACOT7 acyl-CoA thioesterase 7 -0.0199728
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0199141
IGF2R insulin-like growth factor 2 receptor -0.0198418
BTBD7 BTB (POZ) domain containing 7 -0.0198288
PBRM1 polybromo 1 -0.0198011
CR1L complement component (3b/4b) receptor 1-like -0.0197502
CCDC12 coiled-coil domain containing 12 -0.0197011
BCR breakpoint cluster region -0.0196175
MSN moesin -0.0196129
XPO5 exportin 5 -0.0195386
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0195311
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -0.0195028
SPPL3 signal peptide peptidase like 3 -0.0194422
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0193377
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -0.0192949
ENO1 enolase 1, (alpha) -0.0192627
LUZP1 leucine zipper protein 1 -0.0190913
NFYC nuclear transcription factor Y, gamma -0.0190757
EHBP1 EH domain binding protein 1 -0.0190725
CHD1L chromodomain helicase DNA binding protein 1-like -0.0190126
EIF1 eukaryotic translation initiation factor 1 -0.0190026
C1ORF159 chromosome 1 open reading frame 159 -0.0189726
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0189585
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0189035
DARS1 aspartyl-tRNA synthetase 1 -0.0188949
TET3 tet methylcytosine dioxygenase 3 -0.0188768
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0188594
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0188105
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.0187947
ACACA acetyl-CoA carboxylase alpha -0.0187626
MOB3B MOB kinase activator 3B -0.0187461
HPCAL1 hippocalcin-like 1 -0.0187437
RHOBTB3 Rho-related BTB domain containing 3 -0.0187392
GPHN gephyrin -0.0187253
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0186847
LIN9 lin-9 DREAM MuvB core complex component -0.0186777
HBE1 hemoglobin, epsilon 1 -0.0186759
ICE2 interactor of little elongation complex ELL subunit 2 -0.0186636
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0186393
KCTD11 potassium channel tetramerization domain containing 11 -0.01854
GANAB glucosidase, alpha; neutral AB -0.0185285
RFWD3 ring finger and WD repeat domain 3 -0.0184435
GDA guanine deaminase -0.0184072
AK2 adenylate kinase 2 -0.0183413
QKI QKI, KH domain containing, RNA binding -0.0183078
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.0182238
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.018203
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0181779
NOL4L nucleolar protein 4-like -0.0181775
TMEM41B transmembrane protein 41B -0.0181738
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0180902
GFM1 G elongation factor, mitochondrial 1 -0.0180824
SELENOI selenoprotein I -0.0180629
RAI14 retinoic acid induced 14 -0.0180535
REPS1 RALBP1 associated Eps domain containing 1 -0.0180204
CCDC66 coiled-coil domain containing 66 -0.017999
RPL27A ribosomal protein L27a -0.0178909
TMEM164 transmembrane protein 164 -0.0177828
STAT5A signal transducer and activator of transcription 5A -0.0177765
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0177692
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0177429
MTFR1 mitochondrial fission regulator 1 -0.017722
THEM4 thioesterase superfamily member 4 -0.0177187
FKBP5 FK506 binding protein 5 -0.0176737
GPC5 glypican 5 -0.017671
ABHD5 abhydrolase domain containing 5 -0.0176302
INTS9 integrator complex subunit 9 -0.0176248
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.0174318
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0174133
TLK1 tousled-like kinase 1 -0.017362
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.017358
TENM1 teneurin transmembrane protein 1 -0.0172547
SUGP2 SURP and G patch domain containing 2 -0.0171977
WSB1 WD repeat and SOCS box containing 1 -0.0171793
MDN1 MDN1, midasin homolog (yeast) -0.0170788
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0170695
E2F3 E2F transcription factor 3 -0.017067
PTBP2 polypyrimidine tract binding protein 2 -0.0170381
NRDC nardilysin convertase -0.0170196
ARHGAP21 Rho GTPase activating protein 21 -0.0170135
MCPH1 microcephalin 1 -0.0169913
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.01697
EML4 echinoderm microtubule associated protein like 4 -0.0169119
USP47 ubiquitin specific peptidase 47 -0.0168957
BAIAP2L1 BAI1-associated protein 2-like 1 -0.016874
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -0.016857
GDNF glial cell derived neurotrophic factor -0.0168505
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.0168454
MINDY3 MINDY lysine 48 deubiquitinase 3 -0.0168437
VRK1 vaccinia related kinase 1 -0.0168298
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0168102
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.016798
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0167779
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0167379
LDLR low density lipoprotein receptor -0.0166989
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.0166466
CKAP5 cytoskeleton associated protein 5 -0.016644
WWOX WW domain containing oxidoreductase -0.0165355
ETF1 eukaryotic translation termination factor 1 -0.0164816
CEP192 centrosomal protein 192kDa -0.016479
SMC1A structural maintenance of chromosomes 1A -0.0164349
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 -0.0164066
TM9SF4 transmembrane 9 superfamily protein member 4 -0.0164013
PUM3 pumilio RNA binding family member 3 -0.0163994
PRMT3 protein arginine methyltransferase 3 -0.0163624
RPLP1 ribosomal protein, large, P1 -0.0163598
EIF4B eukaryotic translation initiation factor 4B -0.0163433
INTS10 integrator complex subunit 10 -0.0163424
ARHGAP18 Rho GTPase activating protein 18 -0.0162412
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.016208
SQLE squalene epoxidase -0.0162061
NNT nicotinamide nucleotide transhydrogenase -0.0162039
BABAM2 BRISC and BRCA1 A complex member 2 -0.0161885
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0161088
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.0161087
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.01609
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -0.0160793
CFAP20DC CFAP20 domain containing -0.0160757
ANO10 anoctamin 10 -0.0159251
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.015849
FAM168A family with sequence similarity 168, member A -0.0158237
POT1 protection of telomeres 1 -0.0158147
RCC1L RCC1 like -0.0158053
LPIN1 lipin 1 -0.0157867
TANK TRAF family member-associated NFKB activator -0.0157383
RPS15 ribosomal protein S15 -0.0157241
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0157025
CDK6 cyclin-dependent kinase 6 -0.0156907
SLC25A42 solute carrier family 25, member 42 -0.0156603
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0156368
ATP5F1C ATP synthase F1 subunit gamma -0.0156337
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0155928
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0155615
HOMER1 homer scaffolding protein 1 -0.0155254
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -0.0155197
PARD3 par-3 family cell polarity regulator -0.0154994
PDE4A phosphodiesterase 4A, cAMP-specific -0.0154802
PCNX4 pecanex 4 -0.0154613
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.0154498
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0154277
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0153997
WARS1 tryptophanyl-tRNA synthetase 1 -0.0153978
RBM15 RNA binding motif protein 15 -0.0153942
RBM25 RNA binding motif protein 25 -0.0153752
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0153303
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 -0.015259
VIRMA vir like m6A methyltransferase associated -0.0152425
ZYG11A zyg-11 family member A, cell cycle regulator -0.0152371
NLRP1 NLR family, pyrin domain containing 1 -0.0152363
SUN1 Sad1 and UNC84 domain containing 1 -0.0152349
CCDC57 coiled-coil domain containing 57 -0.0152269
KLHL18 kelch-like family member 18 -0.0151981
TMEM131 transmembrane protein 131 -0.0151431
SEC31A SEC31 homolog A (S. cerevisiae) -0.0151401
CDIN1 CDAN1 interacting nuclease 1 -0.0151195
KAZN kazrin, periplakin interacting protein -0.0150743
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0150733
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0150116
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0149774
RPL30 ribosomal protein L30 -0.0149693
PRDX4 peroxiredoxin 4 -0.0148989
AFG2A AFG2 AAA ATPase homolog A -0.0148904
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0148851
MARCHF6 membrane associated ring-CH-type finger 6 -0.0148799
MECR mitochondrial trans-2-enoyl-CoA reductase -0.0148262
STIL SCL/TAL1 interrupting locus -0.0148201
CS citrate synthase -0.0148191
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.0148005
CHD7 chromodomain helicase DNA binding protein 7 -0.0147864
TANGO2 transport and golgi organization 2 homolog (Drosophila) -0.014771
MRPS27 mitochondrial ribosomal protein S27 -0.0147404
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0147017
ANAPC5 anaphase promoting complex subunit 5 -0.0146917
FOXN2 forkhead box N2 -0.0146905
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0146839
ACTG1 actin gamma 1 -0.0146278
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -0.0145905
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.014583
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0145304
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0145062
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0144969
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0144245
TRAPPC10 trafficking protein particle complex 10 -0.0144038
LRRC61 leucine rich repeat containing 61 -0.0143937
POM121 POM121 transmembrane nucleoporin -0.0143844
ZNF644 zinc finger protein 644 -0.0143827
DPH6 diphthamine biosynthesis 6 -0.014367
ENOSF1 enolase superfamily member 1 -0.0143615
ZDHHC17 zinc finger, DHHC-type containing 17 -0.0143158
KMT5B lysine methyltransferase 5B -0.0143119
CTCF CCCTC-binding factor (zinc finger protein) -0.0142689
CCDC47 coiled-coil domain containing 47 -0.0142596
SCG3 secretogranin III -0.0142423
IPO11 importin 11 -0.0142391
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.0142223
GCLM glutamate-cysteine ligase, modifier subunit -0.0142156
FAT1 FAT atypical cadherin 1 -0.014113
SUMF2 sulfatase modifying factor 2 -0.0141092
KDM5B lysine (K)-specific demethylase 5B -0.014103
FAF2 Fas associated factor family member 2 -0.0140975
CNTNAP2 contactin associated protein-like 2 -0.0140722
MYO19 myosin XIX -0.0140672
PDIA3 protein disulfide isomerase family A, member 3 -0.0140562
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0140555
UBL4A ubiquitin-like 4A -0.0140358
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -0.0139737
AGO1 argonaute RISC catalytic component 1 -0.0139546
DTNBP1 dystrobrevin binding protein 1 -0.0139516
EIF3I eukaryotic translation initiation factor 3, subunit I -0.0139362
FCHO2 FCH domain only 2 -0.0139293
ZNF106 zinc finger protein 106 -0.0139023
AATF apoptosis antagonizing transcription factor -0.0138673
USP24 ubiquitin specific peptidase 24 -0.0138494
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0138445
TUBB tubulin, beta class I -0.0138177
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) -0.0137977
ADAT2 adenosine deaminase, tRNA-specific 2 -0.0137843
USP37 ubiquitin specific peptidase 37 -0.0137729
XPO4 exportin 4 -0.0137575
MYO9A myosin IXA -0.0137554
NALF1 NALCN channel auxiliary factor 1 -0.0137521
RHCE Rh blood group, CcEe antigens -0.0137443
RPS16 ribosomal protein S16 -0.0137293
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0137173
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.0137172
NMRAL1 NmrA-like family domain containing 1 -0.0137074
IPO5 importin 5 -0.0137036
ERCC8 excision repair cross-complementation group 8 -0.0136524
ZNF782 zinc finger protein 782 -0.0136522
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -0.013633
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0136312
CLEC16A C-type lectin domain family 16, member A -0.0136175
CEP85 centrosomal protein 85kDa -0.0135994
USP34 ubiquitin specific peptidase 34 -0.0135692
RPS6 ribosomal protein S6 -0.0135233
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0135009
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.0134909
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0134657
MCU mitochondrial calcium uniporter -0.013459
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0134574
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0134384
RPS11 ribosomal protein S11 -0.0134201
AKAP10 A kinase (PRKA) anchor protein 10 -0.0134016
CARNMT1 carnosine N-methyltransferase 1 -0.0133982
NPAT nuclear protein, ataxia-telangiectasia locus -0.0133279
TBC1D15 TBC1 domain family, member 15 -0.0133181
USP25 ubiquitin specific peptidase 25 -0.013304
RO60 Ro60, Y RNA binding protein -0.0132988
TXNIP thioredoxin interacting protein -0.0132861
AFMID arylformamidase -0.0132761
EXOC2 exocyst complex component 2 -0.0132533
ITSN2 intersectin 2 -0.0132472
CUL5 cullin 5 -0.0132394
RBM20 RNA binding motif protein 20 -0.0132341
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0132325
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.0132149
ATP5MC2 ATP synthase membrane subunit c locus 2 -0.0131892
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0131781
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0131664
TTC3 tetratricopeptide repeat domain 3 -0.0131394
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.0131328
ERI1 exoribonuclease 1 -0.0131242
COPG1 coatomer protein complex, subunit gamma 1 -0.0131017
LARS2 leucyl-tRNA synthetase 2, mitochondrial -0.0130977
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -0.0130742
CDR2 cerebellar degeneration-related protein 2, 62kDa -0.0130345
RUFY2 RUN and FYVE domain containing 2 -0.0130177
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -0.0130076
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -0.0129721
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.0129706
EXT2 exostosin glycosyltransferase 2 -0.0129551
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0129526
HBA1 hemoglobin, alpha 1 -0.0129443
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.0129418
PLCD1 phospholipase C, delta 1 -0.0129361
RTTN rotatin -0.0128664
GPBP1 GC-rich promoter binding protein 1 -0.0128555
TUBGCP5 tubulin, gamma complex associated protein 5 -0.0128502
MRPL13 mitochondrial ribosomal protein L13 -0.0128319
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 -0.0128142
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0128137
ACAD10 acyl-CoA dehydrogenase family, member 10 -0.0128114
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0128083
ANKRD28 ankyrin repeat domain 28 -0.0127842
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 -0.0127685
GPR137 G protein-coupled receptor 137 -0.0127534
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0127504
MPHOSPH9 M-phase phosphoprotein 9 -0.0127423
ATXN2 ataxin 2 -0.0127403
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0127354
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -0.012708
CENPB centromere protein B, 80kDa -0.0127
KLHL22 kelch-like family member 22 -0.0126989
KIF15 kinesin family member 15 -0.0126781
PTK2B protein tyrosine kinase 2 beta -0.0126447
CLTC clathrin, heavy chain (Hc) -0.0126385
KIF4A kinesin family member 4A -0.0126351
TM9SF2 transmembrane 9 superfamily member 2 -0.0126061
PPA2 pyrophosphatase (inorganic) 2 -0.0126006
MRPS31 mitochondrial ribosomal protein S31 -0.0125708
MRPS35 mitochondrial ribosomal protein S35 -0.012529
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0125179
SREBF1 sterol regulatory element binding transcription factor 1 -0.0125059
CDH12 cadherin 12, type 2 (N-cadherin 2) -0.0125047
RAB28 RAB28, member RAS oncogene family -0.0124966
SEH1L SEH1-like (S. cerevisiae) -0.0124775
ARTN artemin -0.0124696
HIP1 huntingtin interacting protein 1 -0.0124484
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0124344
MATR3 matrin 3 -0.0124314
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.0124295
NEBL nebulette -0.0124248
RPS23 ribosomal protein S23 -0.0124245
TBCD tubulin folding cofactor D -0.0124227
GCFC2 GC-rich sequence DNA-binding factor 2 -0.0124184
WDR33 WD repeat domain 33 -0.012346
TFDP1 transcription factor Dp-1 -0.0123231
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.0123179