K562_GSK-LSD1 2HCl_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK-LSD1 2HCl 10nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_GSK-LSD1 2HCl_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
VIM vimentin 0.206007
SPTBN1 spectrin, beta, non-erythrocytic 1 0.194756
PKM pyruvate kinase, muscle 0.130716
ADGRB3 adhesion G protein-coupled receptor B3 0.107502
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.101106
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.100659
FAM178B family with sequence similarity 178, member B 0.0980722
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0979834
MAML2 mastermind-like 2 (Drosophila) 0.0946979
BICD1 bicaudal D homolog 1 (Drosophila) 0.0878415
CFAP161 cilia and flagella associated protein 161 0.0859317
ZNF609 zinc finger protein 609 0.0819978
PRKCB protein kinase C, beta 0.0726162
EPB41 erythrocyte membrane protein band 4.1 0.0719371
ZNF124 zinc finger protein 124 0.0712247
SORBS1 sorbin and SH3 domain containing 1 0.0709652
TTC28 tetratricopeptide repeat domain 28 0.0708516
BMP2K BMP2 inducible kinase 0.0693602
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0686128
AFF1 AF4/FMR2 family, member 1 0.0619473
TPM4 tropomyosin 4 0.0616046
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0610958
HSPG2 heparan sulfate proteoglycan 2 0.060992
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.060681
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.0603802
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.060341
DOCK2 dedicator of cytokinesis 2 0.0578851
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0575757
SMYD3 SET and MYND domain containing 3 0.0562883
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0540865
DMD dystrophin 0.0540256
STON2 stonin 2 0.0519773
MYO3B myosin IIIB 0.0518247
LRRC8B leucine rich repeat containing 8 family, member B 0.0516599
CASS4 Cas scaffolding protein family member 4 0.0512748
TBC1D5 TBC1 domain family, member 5 0.0505235
SORT1 sortilin 1 0.0498409
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0498343
MED13L mediator complex subunit 13-like 0.0484576
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0483292
MACF1 microtubule-actin crosslinking factor 1 0.0475014
UBE2H ubiquitin-conjugating enzyme E2H 0.0474682
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.0470321
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0463264
TRPS1 trichorhinophalangeal syndrome I 0.0461029
IQGAP1 IQ motif containing GTPase activating protein 1 0.0458693
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0458621
LAPTM4B lysosomal protein transmembrane 4 beta 0.044819
BSG basigin (Ok blood group) 0.0445999
ASPH aspartate beta-hydroxylase 0.0434224
KIAA1958 KIAA1958 0.0423735
SSBP3 single stranded DNA binding protein 3 0.0421087
RHOH ras homolog family member H 0.0418564
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0417572
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0409581
KIF2A kinesin heavy chain member 2A 0.040859
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0397089
TLE2 transducin-like enhancer of split 2 0.0395042
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0392243
IQGAP2 IQ motif containing GTPase activating protein 2 0.0389128
CELF1 CUGBP, Elav-like family member 1 0.0388969
PHACTR4 phosphatase and actin regulator 4 0.0385616
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.0376617
NFIA nuclear factor I/A 0.0373797
GTF2IRD1 GTF2I repeat domain containing 1 0.036312
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.035929
GRB2 growth factor receptor-bound protein 2 0.0354625
EZR ezrin 0.0352937
EXOC6 exocyst complex component 6 0.03509
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0342858
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0342592
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0330688
GALM galactose mutarotase (aldose 1-epimerase) 0.0330198
BPTF bromodomain PHD finger transcription factor 0.0328628
GAB2 GRB2-associated binding protein 2 0.0326761
LOC112694756 uncharaterized LOC112694756 0.0322121
FRYL FRY-like 0.0320277
KIF13A kinesin family member 13A 0.0318579
DAPK1 death-associated protein kinase 1 0.0317571
SSH2 slingshot protein phosphatase 2 0.0313415
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0311145
PI16 peptidase inhibitor 16 0.0308913
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.030845
FNBP1 formin binding protein 1 0.0308222
TAOK3 TAO kinase 3 0.030596
ENO1 enolase 1, (alpha) 0.0305316
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0304558
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0304407
TEC tec protein tyrosine kinase 0.0300325
RCSD1 RCSD domain containing 1 0.0300008
FNDC3A fibronectin type III domain containing 3A 0.0297467
DOCK8 dedicator of cytokinesis 8 0.0289136
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0287408
DIAPH3 diaphanous-related formin 3 0.0285919
KIF13B kinesin family member 13B 0.0284578
BTBD9 BTB (POZ) domain containing 9 0.0283135
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0282569
ERBIN erbb2 interacting protein 0.0281901
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0280287
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0279955
VAV1 vav 1 guanine nucleotide exchange factor 0.0279374
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0279273
TOX4 TOX high mobility group box family member 4 0.027626
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.027447
AAK1 AP2 associated kinase 1 0.0272514
FBXL13 F-box and leucine-rich repeat protein 13 0.0270896
MYLIP myosin regulatory light chain interacting protein 0.0269743
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0268804
ELF2 E74-like factor 2 (ets domain transcription factor) 0.026811
CLOCK clock circadian regulator 0.0267964
MSI2 musashi RNA-binding protein 2 0.0267688
APOLD1 apolipoprotein L domain containing 1 0.0267474
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0267116
APOC1 apolipoprotein C-I 0.0266699
CRPPA CDP-L-ribitol pyrophosphorylase A 0.0266017
CTSD cathepsin D 0.0265138
GPAT3 glycerol-3-phosphate acyltransferase 3 0.026398
BRD4 bromodomain containing 4 0.0263762
GFI1B growth factor independent 1B transcription repressor 0.0263258
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0262898
RACK1 receptor for activated C kinase 1 0.0262892
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0261902
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0260184
MPZL1 myelin protein zero-like 1 0.0259546
NUCB2 nucleobindin 2 0.0257233
ZFC3H1 zinc finger, C3H1-type containing 0.0257055
MBNL1 muscleblind-like splicing regulator 1 0.0256754
STRBP spermatid perinuclear RNA binding protein 0.0256729
RNF213 ring finger protein 213 0.0256073
FOXP1 forkhead box P1 0.025596
DOCK9 dedicator of cytokinesis 9 0.0255957
INVS inversin 0.0255775
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0255604
TOP1 topoisomerase (DNA) I 0.0253221
OSBPL8 oxysterol binding protein-like 8 0.0247481
CDCP1 CUB domain containing protein 1 0.0247193
HMBOX1 homeobox containing 1 0.0246468
SNX29 sorting nexin 29 0.0246138
IL1R1 interleukin 1 receptor, type I 0.0243494
ZNF644 zinc finger protein 644 0.0242996
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0242363
AHNAK AHNAK nucleoprotein 0.0241202
USP6NL USP6 N-terminal like 0.02403
HIC2 hypermethylated in cancer 2 0.0239397
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0238582
POTEF POTE ankyrin domain family, member F 0.0237579
DIAPH1 diaphanous-related formin 1 0.0235952
TNRC18 trinucleotide repeat containing 18 0.0235587
MCU mitochondrial calcium uniporter 0.0234258
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0233834
PDS5A PDS5 cohesin associated factor A 0.0233815
SFTPA2 surfactant protein A2 0.0233702
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0233234
DENND1B DENN/MADD domain containing 1B 0.0232996
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.0232152
PDE7A phosphodiesterase 7A 0.0229712
VCL vinculin 0.0228436
PICALM phosphatidylinositol binding clathrin assembly protein 0.0227712
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0227408
FLNB filamin B, beta 0.0226456
TGFB1 transforming growth factor, beta 1 0.0226452
RBM39 RNA binding motif protein 39 0.0226365
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.0225464
FN1 fibronectin 1 0.0224962
CLEC16A C-type lectin domain family 16, member A 0.022468
CCDC18 coiled-coil domain containing 18 0.022352
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0222891
NSD2 nuclear receptor binding SET domain protein 2 0.0222482
KDM7A lysine (K)-specific demethylase 7A 0.0222381
NFE2L2 nuclear factor, erythroid 2-like 2 0.0222165
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0221654
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0221317
COMT catechol-O-methyltransferase 0.0220513
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0220163
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0219031
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0218524
PHIP pleckstrin homology domain interacting protein 0.0218467
MTF2 metal response element binding transcription factor 2 0.0217655
ADD1 adducin 1 (alpha) 0.0217344
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0215992
SDCCAG8 serologically defined colon cancer antigen 8 0.0215836
CD53 CD53 molecule 0.0215667
GOLPH3L golgi phosphoprotein 3-like 0.0213946
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.0213706
RABGAP1 RAB GTPase activating protein 1 0.0213659
MAML3 mastermind-like 3 (Drosophila) 0.0213538
MAP2K1 mitogen-activated protein kinase kinase 1 0.0213434
TBC1D7 TBC1 domain family, member 7 0.0212923
ARL5A ADP-ribosylation factor-like 5A 0.0212833
RPN2 ribophorin II 0.0211501
IL16 interleukin 16 0.0209671
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0209539
CTSB cathepsin B 0.0208011
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0207506
PHF21A PHD finger protein 21A 0.0206285
ETV6 ets variant 6 0.0205579
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.020412
ACTG1 actin gamma 1 0.0203528
RYR1 ryanodine receptor 1 (skeletal) 0.0203378
ZNF77 zinc finger protein 77 0.0202712
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.0202431
EP400 E1A binding protein p400 0.0202095
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.020204
STK24 serine/threonine kinase 24 0.0201788
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0201256
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0200879
TPCN1 two pore segment channel 1 0.0200635
DENND4C DENN/MADD domain containing 4C 0.0200432
SNX25 sorting nexin 25 0.0200087
SRSF10 serine/arginine-rich splicing factor 10 0.0199704
ETV1 ets variant 1 0.0198709
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0198652
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.0197834
STIL SCL/TAL1 interrupting locus 0.0197664
CCND3 cyclin D3 0.0197136
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0197082
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.0196221
FYB1 FYN binding protein 1 0.0196202
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0196131
CTTN cortactin 0.0195917
RPL12 ribosomal protein L12 0.0195009
SIL1 SIL1 nucleotide exchange factor 0.019491
PACS1 phosphofurin acidic cluster sorting protein 1 0.0194279
QPRT quinolinate phosphoribosyltransferase 0.0194045
RNF111 ring finger protein 111 0.0193953
DNAH8 dynein, axonemal, heavy chain 8 0.019268
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0191932
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0191635
NF1 neurofibromin 1 0.0191226
MED15 mediator complex subunit 15 0.0190931
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 0.0190572
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0189399
SLC10A7 solute carrier family 10, member 7 0.0189215
USP33 ubiquitin specific peptidase 33 0.0189065
TXNRD1 thioredoxin reductase 1 0.0189047
TUT4 terminal uridylyl transferase 4 0.0188188
RTN3 reticulon 3 0.0187912
RPL5 ribosomal protein L5 0.0187802
SHROOM1 shroom family member 1 0.0187769
VCP valosin containing protein 0.0187591
ITSN1 intersectin 1 (SH3 domain protein) 0.0187108
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 0.0186992
MYO1F myosin IF 0.0186667
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0186073
MRTFA myocardin related transcription factor A 0.0185907
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0184052
SMC4 structural maintenance of chromosomes 4 0.0184049
LGALS1 lectin, galactoside-binding, soluble, 1 0.0183536
CORO2A coronin, actin binding protein, 2A 0.0183346
KMT2D lysine (K)-specific methyltransferase 2D 0.0182881
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0182654
F8 coagulation factor VIII, procoagulant component 0.0182429
CCM2 cerebral cavernous malformation 2 0.0182347
TAPBP TAP binding protein (tapasin) 0.0182271
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0182079
EVI5 ecotropic viral integration site 5 0.0181392
BLTP2 bridge-like lipid transfer protein family member 2 0.017994
ACVR1B activin A receptor, type IB 0.0178998
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0178798
RAI14 retinoic acid induced 14 0.0177626
TLN1 talin 1 0.0177175
RRM2 ribonucleotide reductase M2 0.0176956
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0176828
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0176356
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.0176329
SSH1 slingshot protein phosphatase 1 0.0175924
CBFB core-binding factor, beta subunit 0.0175763
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0175724
EP300 E1A binding protein p300 0.0175402
COG5 component of oligomeric golgi complex 5 0.0174313
BMPR1A bone morphogenetic protein receptor, type IA 0.0173592
SLC22A23 solute carrier family 22, member 23 0.0173434
RPLP1 ribosomal protein, large, P1 0.0173263
CENPE centromere protein E, 312kDa 0.017309
DENND5A DENN/MADD domain containing 5A 0.0172885
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0172587
MFSD8 major facilitator superfamily domain containing 8 0.0171948
PROCR protein C receptor, endothelial 0.0171609
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0171493
CELF2 CUGBP, Elav-like family member 2 0.0170519
STYXL1 serine/threonine/tyrosine interacting-like 1 0.0170291
ODF2 outer dense fiber of sperm tails 2 0.0170254
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0170149
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0169532
COPG2 coatomer protein complex, subunit gamma 2 0.0169393
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0168887
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0168868
MCM4 minichromosome maintenance complex component 4 0.0168154
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0168092
KRT18 keratin 18, type I 0.0167979
TMEM245 transmembrane protein 245 0.016757
MILR1 mast cell immunoglobulin-like receptor 1 0.0167118
DIPK1A divergent protein kinase domain 1A 0.0166869
LAMB1 laminin, beta 1 0.0166454
HDAC7 histone deacetylase 7 0.0165976
CCNT1 cyclin T1 0.0165868
TMEM65 transmembrane protein 65 0.0165638
CCNY cyclin Y 0.0165509
MRPS18B mitochondrial ribosomal protein S18B 0.016503
IGF2R insulin-like growth factor 2 receptor 0.0164947
CSPP1 centrosome and spindle pole associated protein 1 0.0164849
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0163798
RNF144A ring finger protein 144A 0.016235
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.0162287
KLHDC10 kelch domain containing 10 0.0162257
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.0161954
RBMX RNA binding motif protein, X-linked 0.0161675
CCSER2 coiled-coil serine-rich protein 2 0.01614
TGFBR1 transforming growth factor, beta receptor 1 0.0161183
MYO18B myosin XVIIIB 0.0160598
LMTK2 lemur tyrosine kinase 2 0.0160579
PCED1B PC-esterase domain containing 1B 0.0160232
PKN1 protein kinase N1 0.01598
SNX5 sorting nexin 5 0.0159662
PDZD8 PDZ domain containing 8 0.0159604
EDARADD EDAR-associated death domain 0.0159036
ANXA7 annexin A7 0.0158987
HSPB1 heat shock 27kDa protein 1 0.0158581
ABHD3 abhydrolase domain containing 3 0.0158379
ATM ATM serine/threonine kinase 0.0158312
DEK DEK proto-oncogene 0.0158187
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0158129
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.0158076
IL6ST interleukin 6 signal transducer 0.0158017
MMP12 matrix metallopeptidase 12 0.0157081
MTIF2 mitochondrial translational initiation factor 2 0.0156976
TMEM263 transmembrane protein 263 0.0156863
NCOA6 nuclear receptor coactivator 6 0.0156554
ZMIZ1 zinc finger, MIZ-type containing 1 0.0156164
GATAD2A GATA zinc finger domain containing 2A 0.0155723
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.0154583
BRCA1 breast cancer 1, early onset 0.015453
CDC14A cell division cycle 14A 0.0154479
ATP5F1B ATP synthase F1 subunit beta 0.0154198
POGZ pogo transposable element with ZNF domain 0.0154182
KLHL23 kelch-like family member 23 0.0153584
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0153403
ASCC1 activating signal cointegrator 1 complex subunit 1 0.0152872
ATP13A3 ATPase type 13A3 0.0152814
POFUT4 protein O-fucosyltransferase 4 0.0152778
KIF5B kinesin family member 5B 0.0152756
GPATCH8 G patch domain containing 8 0.015232
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0152168
CYREN cell cycle regulator of NHEJ 0.0151882
SIMC1 SUMO-interacting motifs containing 1 0.0151828
SCAND3 SCAN domain containing 3 0.0151613
CALR calreticulin 0.0151383
ARHGAP35 Rho GTPase activating protein 35 0.0151104
METAP2 methionyl aminopeptidase 2 0.0150723
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.0150322
CTSS cathepsin S 0.0149221
DGKZ diacylglycerol kinase, zeta 0.0149144
COP1 COP1 E3 ubiquitin ligase 0.014876
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.0148706
ARHGAP24 Rho GTPase activating protein 24 0.0147907
MYO16 myosin XVI 0.0147688
PCM1 pericentriolar material 1 0.0147237
RPL11 ribosomal protein L11 0.0147148
TRAPPC8 trafficking protein particle complex 8 0.0146434
RBBP8 retinoblastoma binding protein 8 0.0146351
GSDME gasdermin E 0.0145859
NMT2 N-myristoyltransferase 2 0.01454
CERS6 ceramide synthase 6 0.0144864
STAT2 signal transducer and activator of transcription 2, 113kDa 0.0144829
CCNI cyclin I 0.0144638
CENPB centromere protein B, 80kDa 0.0144629
SEC24C SEC24 family member C 0.0144603
BLM Bloom syndrome, RecQ helicase-like 0.0144499
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.0144491
NRCAM neuronal cell adhesion molecule 0.0144234
MRPL40 mitochondrial ribosomal protein L40 0.014403
LPAR5 lysophosphatidic acid receptor 5 0.014393
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0143643
FAM117A family with sequence similarity 117, member A 0.0143619
RESF1 retroelement silencing factor 1 0.0143602
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 0.0143445
TLE5 TLE family member 5, transcriptional modulator 0.0142832
PRKX protein kinase, X-linked 0.0142354
PRR11 proline rich 11 0.0142297
TPM3 tropomyosin 3 0.0142239
ADIPOR2 adiponectin receptor 2 0.0142143
DGCR2 DiGeorge syndrome critical region gene 2 0.0141905
ADGRE5 adhesion G protein-coupled receptor E5 0.014177
TTBK2 tau tubulin kinase 2 0.0141245
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.0140916
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0140497
FAM184A family with sequence similarity 184, member A 0.0140495
ZFP36L2 ZFP36 ring finger protein-like 2 0.0140408
UBE4A ubiquitination factor E4A 0.0140297
GLMN glomulin, FKBP associated protein 0.0140067
PCNX1 pecanex 1 0.0140062
SLC35F2 solute carrier family 35, member F2 0.0139758
KDM1A lysine (K)-specific demethylase 1A 0.0139727
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.0139564
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0139505
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.013917
RIPOR3 RIPOR family member 3 0.0139053
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0138821
TEX9 testis expressed 9 0.0138279
H2BC11 H2B clustered histone 11 0.0137516
TGOLN2 trans-golgi network protein 2 0.0137361
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0137274
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0137145
DMWD dystrophia myotonica, WD repeat containing 0.0137009
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.013699
NUP62 nucleoporin 62kDa 0.0136944
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0136897
GARRE1 granule associated Rac and RHOG effector 1 0.0136357
RYK receptor-like tyrosine kinase 0.013606
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 0.0135828
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.0135763
KIF21A kinesin family member 21A 0.0135705
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.013566
CLCN5 chloride channel, voltage-sensitive 5 0.0135557
TMEM156 transmembrane protein 156 0.0135433
POT1 protection of telomeres 1 0.0135374
CA8 carbonic anhydrase VIII 0.0135036
SAMD8 sterile alpha motif domain containing 8 0.013436
NME7 NME/NM23 family member 7 0.0134209
TIPRL TOR signaling pathway regulator 0.0134185
RSU1 Ras suppressor protein 1 0.013397
MAP2K5 mitogen-activated protein kinase kinase 5 0.0133447
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.0133398
KATNIP katanin interacting protein 0.0133278
CD3D CD3d molecule, delta (CD3-TCR complex) 0.0132699
GLG1 golgi glycoprotein 1 0.0132287
LTAP1 lipid transport auxiliary protein 1 0.0131993
SCARB1 scavenger receptor class B, member 1 0.01319
FTL ferritin, light polypeptide 0.0131687
ZNF217 zinc finger protein 217 0.0131443
RSF1 remodeling and spacing factor 1 0.013122
LEPROT leptin receptor overlapping transcript 0.0131164
KMT2A lysine (K)-specific methyltransferase 2A 0.01307
KIAA0040 KIAA0040 0.0130496
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.0130141
BCAS3 breast carcinoma amplified sequence 3 0.0129833
DSTYK dual serine/threonine and tyrosine protein kinase 0.0129821
RSPH3 radial spoke 3 homolog (Chlamydomonas) 0.0129315
MAP7 microtubule-associated protein 7 0.0129193
YJU2B YJU2 splicing factor homolog B 0.0128816
BTG1 B-cell translocation gene 1, anti-proliferative 0.012852
PGGT1B protein geranylgeranyltransferase type I, beta subunit 0.0128512
ADNP activity-dependent neuroprotector homeobox 0.0128422
RPTOR regulatory associated protein of MTOR, complex 1 0.0128393
RHOG ras homolog family member G 0.0128301
CCNG1 cyclin G1 0.0128289
BCAP29 B-cell receptor-associated protein 29 0.0128271
TACC3 transforming, acidic coiled-coil containing protein 3 0.0128122
PLD3 phospholipase D family, member 3 0.0128018
VARS1 valyl-tRNA synthetase 1 0.0127982
MYADM myeloid-associated differentiation marker 0.0127888
PHC2 polyhomeotic homolog 2 (Drosophila) 0.0127682
ELOVL6 ELOVL fatty acid elongase 6 0.0127543
RABGAP1L RAB GTPase activating protein 1-like 0.0126973
EPAS1 endothelial PAS domain protein 1 0.0126842
MEIS1 Meis homeobox 1 0.0126539
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0126509
WT1 Wilms tumor 1 0.012637
SNX4 sorting nexin 4 0.0126285
TUBB tubulin, beta class I 0.0126246
LMBR1L limb development membrane protein 1-like 0.0125947
EMC7 ER membrane protein complex subunit 7 0.0125713
LIMA1 LIM domain and actin binding 1 0.012564
AKR1C1 aldo-keto reductase family 1, member C1 0.0125239
PIBF1 progesterone immunomodulatory binding factor 1 0.0125215
ANAPC7 anaphase promoting complex subunit 7 0.0125064
TPT1 tumor protein, translationally-controlled 1 0.0124898
TDRD3 tudor domain containing 3 0.0124539
ATF6 activating transcription factor 6 0.0124368
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0124308
ENSA endosulfine alpha 0.012396
TCTN3 tectonic family member 3 0.012387
DNMBP dynamin binding protein 0.0123865
MKRN1 makorin ring finger protein 1 0.0123776
ACBD3 acyl-CoA binding domain containing 3 0.0123721
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0123573
PHACTR1 phosphatase and actin regulator 1 0.0123567
MARK2 MAP/microtubule affinity-regulating kinase 2 0.0123396
RAP1A RAP1A, member of RAS oncogene family 0.0123292
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.012326
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 0.0123011
PDE4D phosphodiesterase 4D, cAMP-specific 0.0122513
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0122265
ATG5 autophagy related 5 0.0122191
JAK1 Janus kinase 1 0.0121836
STK38 serine/threonine kinase 38 0.0121757
MPRIP myosin phosphatase Rho interacting protein 0.0121602
AKIRIN1 akirin 1 0.0121581
GTF2IRD2B GTF2I repeat domain containing 2B 0.012149
SMG5 SMG5 nonsense mediated mRNA decay factor 0.0120962
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0120836
CEP57L1 centrosomal protein 57kDa-like 1 0.0120831
PCYOX1 prenylcysteine oxidase 1 0.0120769
MYH10 myosin, heavy chain 10, non-muscle 0.0120696
VEPH1 ventricular zone expressed PH domain-containing 1 0.0120678
DOCK11 dedicator of cytokinesis 11 0.0120656
TMEM41A transmembrane protein 41A 0.0120574
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.012056
TUG1 taurine up-regulated 1 (non-protein coding) 0.0120513
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.0120365

decreased expression

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase -0.145534
PRKCA protein kinase C, alpha -0.12152
ZFPM2 zinc finger protein, FOG family member 2 -0.109355
FGF13 fibroblast growth factor 13 -0.0807366
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0745544
ANK1 ankyrin 1, erythrocytic -0.0700906
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0695202
ARL15 ADP-ribosylation factor-like 15 -0.0674781
RORA RAR-related orphan receptor A -0.0668191
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0643559
HBG2 hemoglobin, gamma G -0.0585535
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0563432
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0539476
JMJD1C jumonji domain containing 1C -0.0535306
VWDE von Willebrand factor D and EGF domains -0.0510377
PUS7 pseudouridylate synthase 7 (putative) -0.0502989
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0501705
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0501575
MARCHF3 membrane associated ring-CH-type finger 3 -0.0497063
NMU neuromedin U -0.0474268
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0471113
JARID2 jumonji, AT rich interactive domain 2 -0.0456178
SOS1 son of sevenless homolog 1 (Drosophila) -0.045179
MDN1 MDN1, midasin homolog (yeast) -0.044669
TFRC transferrin receptor -0.0432559
RHOBTB3 Rho-related BTB domain containing 3 -0.04275
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0424836
CNKSR3 CNKSR family member 3 -0.0423694
TBL1X transducin (beta)-like 1X-linked -0.0417242
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.041645
SCFD2 sec1 family domain containing 2 -0.0415597
HBG1 hemoglobin, gamma A -0.0413917
AK1 adenylate kinase 1 -0.0399782
USP15 ubiquitin specific peptidase 15 -0.0399649
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0398215
SMIM44 small integral membrane protein 44 -0.0392355
AIG1 androgen-induced 1 -0.0391088
UBE3C ubiquitin protein ligase E3C -0.0382242
NBAS neuroblastoma amplified sequence -0.0379666
SLC38A1 solute carrier family 38, member 1 -0.0367972
MLXIP MLX interacting protein -0.036092
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0356645
RAD51B RAD51 paralog B -0.0356591
ZEB2 zinc finger E-box binding homeobox 2 -0.0353985
FKBP5 FK506 binding protein 5 -0.0352964
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0350146
ACACA acetyl-CoA carboxylase alpha -0.0349883
RTN4 reticulon 4 -0.0347281
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -0.0341347
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0336568
SRRM2 serine/arginine repetitive matrix 2 -0.0335525
ATXN2 ataxin 2 -0.0332848
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0328293
TASOR2 transcription activation suppressor family member 2 -0.0323479
JAK2 Janus kinase 2 -0.0320445
FBXO42 F-box protein 42 -0.0319002
ESYT2 extended synaptotagmin-like protein 2 -0.031792
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0317852
SETD5 SET domain containing 5 -0.031743
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0315987
CENPP centromere protein P -0.0307939
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0306762
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0306226
BIRC6 baculoviral IAP repeat containing 6 -0.0306112
CTBP2 C-terminal binding protein 2 -0.0305298
TMEM87A transmembrane protein 87A -0.0303785
DLG1 discs, large homolog 1 (Drosophila) -0.0303158
ATAD5 ATPase family, AAA domain containing 5 -0.0301321
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0298498
AFG2A AFG2 AAA ATPase homolog A -0.0292476
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0292276
CNST consortin, connexin sorting protein -0.029178
DARS1 aspartyl-tRNA synthetase 1 -0.0291697
NUP214 nucleoporin 214kDa -0.0291158
PTGES2 prostaglandin E synthase 2 -0.029031
RNF217 ring finger protein 217 -0.0290215
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0287977
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0286472
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0285642
SQLE squalene epoxidase -0.0285626
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.0285136
RHAG Rh-associated glycoprotein -0.0283484
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0282819
USP34 ubiquitin specific peptidase 34 -0.028147
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0280433
KAZN kazrin, periplakin interacting protein -0.0280257
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0280121
TCF12 transcription factor 12 -0.0278185
NRDC nardilysin convertase -0.0276073
SELENOI selenoprotein I -0.0273378
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0273357
FNDC3B fibronectin type III domain containing 3B -0.0272948
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.027222
MARCHF6 membrane associated ring-CH-type finger 6 -0.0271399
CAPN2 calpain 2, (m/II) large subunit -0.0271164
ECPAS Ecm29 proteasome adaptor and scaffold -0.0268583
MEIOB meiosis specific with OB domains -0.0268268
MVD mevalonate (diphospho) decarboxylase -0.0266522
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -0.0265425
PBRM1 polybromo 1 -0.0263728
TRIM33 tripartite motif containing 33 -0.0263683
MBD5 methyl-CpG binding domain protein 5 -0.0263085
SCLT1 sodium channel and clathrin linker 1 -0.0262817
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0262584
IDE insulin-degrading enzyme -0.0261054
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0257203
RCOR1 REST corepressor 1 -0.025455
CCDC91 coiled-coil domain containing 91 -0.0253737
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.0252737
EEF2K eukaryotic elongation factor 2 kinase -0.0250203
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0249697
YARS1 tyrosyl-tRNA synthetase 1 -0.0246828
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.024489
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0243502
CDK6 cyclin-dependent kinase 6 -0.0242645
PUM2 pumilio RNA-binding family member 2 -0.0242589
NOL10 nucleolar protein 10 -0.0240161
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0238208
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0237464
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0237405
DNAH14 dynein, axonemal, heavy chain 14 -0.0236836
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0235882
SUSD1 sushi domain containing 1 -0.0235492
CUL1 cullin 1 -0.0235477
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.0235002
BRWD1 bromodomain and WD repeat domain containing 1 -0.0234949
OSBPL3 oxysterol binding protein-like 3 -0.023471
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0233936
SRPK2 SRSF protein kinase 2 -0.023383
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.0233544
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0233037
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0232174
CALU calumenin -0.0232134
AHCTF1 AT hook containing transcription factor 1 -0.0231423
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0231298
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0231117
XPO5 exportin 5 -0.022875
ZNF292 zinc finger protein 292 -0.022792
NSD1 nuclear receptor binding SET domain protein 1 -0.0227725
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.022699
UBE2K ubiquitin-conjugating enzyme E2K -0.0226948
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.022677
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0226283
DENND1A DENN/MADD domain containing 1A -0.0225852
CDK19 cyclin-dependent kinase 19 -0.0224507
MEF2C myocyte enhancer factor 2C -0.0224119
FANCA Fanconi anemia, complementation group A -0.0223958
FDPS farnesyl diphosphate synthase -0.0221188
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0221183
MRPS27 mitochondrial ribosomal protein S27 -0.0221103
IMMT inner membrane protein, mitochondrial -0.0220179
FAM222B family with sequence similarity 222, member B -0.0218887
ELOVL5 ELOVL fatty acid elongase 5 -0.0217976
FHIT fragile histidine triad -0.0217888
ZNRF3 zinc and ring finger 3 -0.0216706
AGO2 argonaute RISC catalytic component 2 -0.0216657
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0215987
ANKRD11 ankyrin repeat domain 11 -0.0215896
RNF145 ring finger protein 145 -0.0215851
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0215155
AARS1 alanyl-tRNA synthetase 1 -0.0213448
RHEB Ras homolog enriched in brain -0.0212477
ARHGAP6 Rho GTPase activating protein 6 -0.0210555
TET3 tet methylcytosine dioxygenase 3 -0.0210299
RBBP4 retinoblastoma binding protein 4 -0.0208953
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0208741
FNBP4 formin binding protein 4 -0.0208545
TRIM24 tripartite motif containing 24 -0.0208481
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0208323
HELZ helicase with zinc finger -0.0207687
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0207538
PTK2B protein tyrosine kinase 2 beta -0.020619
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0205883
UIMC1 ubiquitin interaction motif containing 1 -0.020536
ATP5MC3 ATP synthase membrane subunit c locus 3 -0.0205028
SPIRE1 spire-type actin nucleation factor 1 -0.0204953
TMC6 transmembrane channel-like 6 -0.0204849
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.0204818
UNC13D unc-13 homolog D (C. elegans) -0.0204402
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0202456
EIF4E eukaryotic translation initiation factor 4E -0.0201943
MTOR mechanistic target of rapamycin (serine/threonine kinase) -0.0201725
REPS1 RALBP1 associated Eps domain containing 1 -0.0201313
ZMYND8 zinc finger, MYND-type containing 8 -0.0200392
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0200205
DOK7 docking protein 7 -0.0200161
NOL9 nucleolar protein 9 -0.0199962
TRIM37 tripartite motif containing 37 -0.0199763
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0199596
IPO7 importin 7 -0.0198809
TTC3 tetratricopeptide repeat domain 3 -0.0198279
CUX1 cut-like homeobox 1 -0.0198083
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0197558
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0197335
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.0196613
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0196264
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.019619
MED13 mediator complex subunit 13 -0.0195164
IPO11 importin 11 -0.0195077
NCOR2 nuclear receptor corepressor 2 -0.019483
PTRH2 peptidyl-tRNA hydrolase 2 -0.0194516
YEATS2 YEATS domain containing 2 -0.0194106
LRRC61 leucine rich repeat containing 61 -0.019388
HEATR1 HEAT repeat containing 1 -0.0193732
LTBP1 latent transforming growth factor beta binding protein 1 -0.0193569
TMEM209 transmembrane protein 209 -0.0193441
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.0193173
RAB10 RAB10, member RAS oncogene family -0.0193038
HIPK2 homeodomain interacting protein kinase 2 -0.019246
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.0192223
NKTR natural killer cell triggering receptor -0.0192204
COPA coatomer protein complex, subunit alpha -0.0192011
TSC22D2 TSC22 domain family, member 2 -0.0191772
SCAF4 SR-related CTD-associated factor 4 -0.019129
FTO fat mass and obesity associated -0.0191002
QKI QKI, KH domain containing, RNA binding -0.0190698
TPST2 tyrosylprotein sulfotransferase 2 -0.0190449
FASTKD1 FAST kinase domains 1 -0.0189775
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0189661
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0188886
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0188797
R3HDM1 R3H domain containing 1 -0.0188558
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -0.0188449
STAU1 staufen double-stranded RNA binding protein 1 -0.0188385
ZBTB35 zinc finger and BTB domain containing 35 -0.0187942
KDM4B lysine (K)-specific demethylase 4B -0.0187234
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0187005
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0186887
ABHD18 abhydrolase domain containing 18 -0.0186487
EIF3M eukaryotic translation initiation factor 3, subunit M -0.0186238
H2AC6 H2A clustered histone 6 -0.0186077
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.0185472
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein -0.0185035
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.0184926
LARS1 leucyl-tRNA synthetase 1 -0.0184648
ENOSF1 enolase superfamily member 1 -0.0184478
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0184385
ACTN1 actinin, alpha 1 -0.0184311
RABL6 RAB, member RAS oncogene family-like 6 -0.0184153
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0184094
PCDH9 protocadherin 9 -0.0183907
DNAAF9 dynein axonemal assembly factor 9 -0.0183418
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0182759
METTL8 methyltransferase like 8 -0.0182237
DCAKD dephospho-CoA kinase domain containing -0.0182065
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.018199
FRRS1 ferric-chelate reductase 1 -0.0181898
ZNF791 zinc finger protein 791 -0.0181821
LMBR1 limb development membrane protein 1 -0.0181701
C17ORF99 chromosome 17 open reading frame 99 -0.0181396
STRN3 striatin, calmodulin binding protein 3 -0.018128
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0181136
NEBL nebulette -0.0180997
SEC31A SEC31 homolog A (S. cerevisiae) -0.0180825
FAM13A family with sequence similarity 13, member A -0.0180746
VRK1 vaccinia related kinase 1 -0.0180703
MYO1D myosin ID -0.0180257
UBAC1 UBA domain containing 1 -0.0179944
ERI1 exoribonuclease 1 -0.017987
DEAF1 DEAF1 transcription factor -0.0178931
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.0178672
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0178013
USP48 ubiquitin specific peptidase 48 -0.017792
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0177819
MOB3B MOB kinase activator 3B -0.0177695
TMEM164 transmembrane protein 164 -0.0176326
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -0.0176273
GMPS guanine monphosphate synthase -0.0175926
ZNF106 zinc finger protein 106 -0.0175297
MRPL20 mitochondrial ribosomal protein L20 -0.0174936
LCORL ligand dependent nuclear receptor corepressor-like -0.017485
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0174569
RO60 Ro60, Y RNA binding protein -0.0174475
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.0173934
PDE4A phosphodiesterase 4A, cAMP-specific -0.0173729
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0173414
TRAPPC12 trafficking protein particle complex 12 -0.0173394
ARID1A AT rich interactive domain 1A (SWI-like) -0.0172853
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.0172789
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0172134
KRIT1 KRIT1, ankyrin repeat containing -0.0171951
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0171877
SFMBT2 Scm-like with four mbt domains 2 -0.017184
INTS6L integrator complex subunit 6 like -0.0171499
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0171403
RPS12 ribosomal protein S12 -0.0171025
GSTCD glutathione S-transferase, C-terminal domain containing -0.017098
CEP152 centrosomal protein 152kDa -0.017062
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0170025
UBE4B ubiquitination factor E4B -0.0170007
TNPO2 transportin 2 -0.0169837
ACO2 aconitase 2, mitochondrial -0.016924
WRN Werner syndrome, RecQ helicase-like -0.016911
EVL Enah/Vasp-like -0.0168961
UBL4A ubiquitin-like 4A -0.01689
TFR2 transferrin receptor 2 -0.0168228
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0168019
GMDS GDP-mannose 4,6-dehydratase -0.0167862
RPS19 ribosomal protein S19 -0.0167783
HOMER1 homer scaffolding protein 1 -0.0166403
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.016616
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.016606
WDR44 WD repeat domain 44 -0.0165747
TENM1 teneurin transmembrane protein 1 -0.0165628
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0165616
EIF5B eukaryotic translation initiation factor 5B -0.0165543
COMMD10 COMM domain containing 10 -0.0165346
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0164674
BTF3L4 basic transcription factor 3-like 4 -0.016352
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0163268
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.0161998
LONP2 lon peptidase 2, peroxisomal -0.0161459
C1ORF159 chromosome 1 open reading frame 159 -0.0161058
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0161027
TMOD1 tropomodulin 1 -0.0160167
DHCR24 24-dehydrocholesterol reductase -0.0159756
CFDP1 craniofacial development protein 1 -0.0159357
GON4L gon-4-like (C. elegans) -0.0159224
FUBP3 far upstream element (FUSE) binding protein 3 -0.0158848
BBX bobby sox homolog (Drosophila) -0.0158636
SEC13 SEC13 homolog (S. cerevisiae) -0.0158358
PDIA3 protein disulfide isomerase family A, member 3 -0.0158136
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0158127
GDA guanine deaminase -0.0158047
GATA1 GATA binding protein 1 (globin transcription factor 1) -0.0157728
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0157314
RFWD3 ring finger and WD repeat domain 3 -0.0157185
ZNF611 zinc finger protein 611 -0.0156665
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0156231
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.0155944
AHDC1 AT hook, DNA binding motif, containing 1 -0.015589
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.0155725
CDC37 cell division cycle 37 -0.0155651
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.0155386
MTFR1 mitochondrial fission regulator 1 -0.015534
AGO3 argonaute RISC catalytic component 3 -0.0155322
BMAL2 basic helix-loop-helix ARNT like 2 -0.0155294
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0155278
KIFC3 kinesin family member C3 -0.0155108
SFXN5 sideroflexin 5 -0.0155055
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.015502
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.0154927
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0154835
TFCP2 transcription factor CP2 -0.0154539
GLB1 galactosidase, beta 1 -0.0154516
GMPR guanosine monophosphate reductase -0.0154417
SERGEF secretion regulating guanine nucleotide exchange factor -0.0154356
RBM15 RNA binding motif protein 15 -0.0154214
MTX2 metaxin 2 -0.015413
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.01539
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.0153461
INTS6 integrator complex subunit 6 -0.0153386
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0153135
HIP1 huntingtin interacting protein 1 -0.0153069
GOLM2 golgi membrane protein 2 -0.0152843
CENPC centromere protein C -0.015281
LIMD1 LIM domains containing 1 -0.0152709
INO80 INO80 complex subunit -0.015265
SAMD4A sterile alpha motif domain containing 4A -0.0152608
TMEM44 transmembrane protein 44 -0.0152366
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.0152131
RPS16 ribosomal protein S16 -0.0152001
EXOC3L2 exocyst complex component 3-like 2 -0.0151849
CDCA2 cell division cycle associated 2 -0.0150821
METTL15 methyltransferase like 15 -0.0150808
TJP1 tight junction protein 1 -0.0150789
TOMM70 translocase of outer mitochondrial membrane 70 -0.0150728
ZC3H13 zinc finger CCCH-type containing 13 -0.0150585
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -0.0150437
LDAH lipid droplet associated hydrolase -0.0150234
WDR7 WD repeat domain 7 -0.0150164
ATF7IP activating transcription factor 7 interacting protein -0.0150129
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0149498
GGT7 gamma-glutamyltransferase 7 -0.0149005
FXR1 fragile X mental retardation, autosomal homolog 1 -0.0148642
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.014858
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -0.0148509
KDM2A lysine (K)-specific demethylase 2A -0.0148449
HOOK3 hook microtubule-tethering protein 3 -0.0148334
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0148305
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.01482
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0148198
TTC7B tetratricopeptide repeat domain 7B -0.0148151
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -0.0148149
PLCD1 phospholipase C, delta 1 -0.0148136
FKBP14 FK506 binding protein 14, 22 kDa -0.0147533
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -0.0147512
SERBP1 SERPINE1 mRNA binding protein 1 -0.0146823
DNM2 dynamin 2 -0.0146701
KDM3B lysine (K)-specific demethylase 3B -0.0146609
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.014659
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -0.014655
MTG2 mitochondrial ribosome-associated GTPase 2 -0.0146269
BCL2L1 BCL2-like 1 -0.0146165
ACBD6 acyl-CoA binding domain containing 6 -0.014603
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0145713
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0145628
ARHGAP21 Rho GTPase activating protein 21 -0.0145245
LDLR low density lipoprotein receptor -0.0145149
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 -0.0144988
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.014454
KMT2C lysine (K)-specific methyltransferase 2C -0.0144406
EXOC2 exocyst complex component 2 -0.0144362
CDC45 cell division cycle 45 -0.0143948
AGPS alkylglycerone phosphate synthase -0.014377
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0143747
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0143572
BLTP3A bridge-like lipid transfer protein family member 3A -0.0143501
UBXN2A UBX domain protein 2A -0.0143421
NIN ninein (GSK3B interacting protein) -0.0143365
KIF14 kinesin family member 14 -0.014297
HDAC5 histone deacetylase 5 -0.0142937
KIF2C kinesin family member 2C -0.0142406
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0142075
RBM10 RNA binding motif protein 10 -0.0141997
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0141869
GLRX3 glutaredoxin 3 -0.0141851
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -0.0141849
RC3H1 ring finger and CCCH-type domains 1 -0.0141772
GSE1 Gse1 coiled-coil protein -0.0141399
LUC7L LUC7-like (S. cerevisiae) -0.0141172
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0141057
ATAD2B ATPase family, AAA domain containing 2B -0.0141039
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0140947
AAGAB alpha- and gamma-adaptin binding protein -0.0140918
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0140912
RBM20 RNA binding motif protein 20 -0.0140506
PITRM1 pitrilysin metallopeptidase 1 -0.0140433
PARVB parvin, beta -0.0139887
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -0.0139874
AFF4 AF4/FMR2 family, member 4 -0.0139754
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0139721
TM9SF3 transmembrane 9 superfamily member 3 -0.0139653
UBE3D ubiquitin protein ligase E3D -0.0139399
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0139232
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.0138875
SINHCAF SIN3-HDAC complex associated factor -0.0138805
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0138216
ZNF804B zinc finger protein 804B -0.0138104
RPL31 ribosomal protein L31 -0.0137777
SCG3 secretogranin III -0.0137199
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0137155
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0137126
EXOSC1 exosome component 1 -0.0136962
IREB2 iron-responsive element binding protein 2 -0.0136941
FAM193B family with sequence similarity 193, member B -0.0136865
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0136831
CSNK1A1 casein kinase 1, alpha 1 -0.0136689
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -0.0136132
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -0.0136042
WNK1 WNK lysine deficient protein kinase 1 -0.0136017
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0135981
PIF1 PIF1 5'-to-3' DNA helicase -0.013584
TSC2 tuberous sclerosis 2 -0.01358
INTS9 integrator complex subunit 9 -0.0135492
PRRC2A proline-rich coiled-coil 2A -0.0134865
TENT2 terminal nucleotidyltransferase 2 -0.0134848
TAOK1 TAO kinase 1 -0.0134759
FBXW11 F-box and WD repeat domain containing 11 -0.0134507
NLK nemo-like kinase -0.0134414
PLIN4 perilipin 4 -0.013417
LYRM4 LYR motif containing 4 -0.0133862
ETF1 eukaryotic translation termination factor 1 -0.0133447
RPS21 ribosomal protein S21 -0.013311
PTPRA protein tyrosine phosphatase, receptor type, A -0.0132607
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae) -0.0132419
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.0132342
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0132145
CR1L complement component (3b/4b) receptor 1-like -0.0132008
EML4 echinoderm microtubule associated protein like 4 -0.0131931
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.0131705
XPO1 exportin 1 -0.0131479
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0131384
RAD17 RAD17 homolog (S. pombe) -0.0131217
NUP188 nucleoporin 188kDa -0.0131158
ADD3 adducin 3 (gamma) -0.0131041
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -0.0130479
RANBP2 RAN binding protein 2 -0.0130382
CENPI centromere protein I -0.0130366
SBF2 SET binding factor 2 -0.0130179
LARP1B La ribonucleoprotein domain family, member 1B -0.0130126
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.0130106
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.0130023
BCL7A B-cell CLL/lymphoma 7A -0.0130019
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0129818
PDCD10 programmed cell death 10 -0.0129792
ZNF804A zinc finger protein 804A -0.0129665
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0129243
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0129153
KDM4C lysine (K)-specific demethylase 4C -0.0128857
FAR1 fatty acyl CoA reductase 1 -0.0128834
CRLF3 cytokine receptor-like factor 3 -0.0128348
AQR aquarius intron-binding spliceosomal factor -0.0128333
PPARD peroxisome proliferator-activated receptor delta -0.0128096
BABAM2 BRISC and BRCA1 A complex member 2 -0.0128005
TEX10 testis expressed 10 -0.0127876
CCDC57 coiled-coil domain containing 57 -0.0127736
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0127703
KAT6A K(lysine) acetyltransferase 6A -0.0127657
WAC WW domain containing adaptor with coiled-coil -0.0127656