K562_NVP-BSK805 2HCl_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description NVP-BSK805 2HCl 10µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_NVP-BSK805 2HCl_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase 0.404525
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.115154
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.112018
RABGAP1L RAB GTPase activating protein 1-like 0.0993842
RPLP1 ribosomal protein, large, P1 0.0827661
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0774458
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0771372
GPC5 glypican 5 0.0744635
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0718164
SQSTM1 sequestosome 1 0.0713426
ZFPM2 zinc finger protein, FOG family member 2 0.0710937
LMBR1 limb development membrane protein 1 0.0679593
ADGRV1 adhesion G protein-coupled receptor V1 0.0676373
RPS2 ribosomal protein S2 0.0672465
MYO3B myosin IIIB 0.0652545
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.0551346
RPS8 ribosomal protein S8 0.0549109
RPL13A ribosomal protein L13a 0.052479
GMPR guanosine monophosphate reductase 0.0523684
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0522125
RPL32 ribosomal protein L32 0.0514625
RTN4 reticulon 4 0.0494941
VCL vinculin 0.0488836
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0469763
TBC1D5 TBC1 domain family, member 5 0.0469362
ZBTB20 zinc finger and BTB domain containing 20 0.0437997
ELOVL6 ELOVL fatty acid elongase 6 0.0421914
TCF12 transcription factor 12 0.0412068
DOCK11 dedicator of cytokinesis 11 0.0409888
ENOSF1 enolase superfamily member 1 0.0406862
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.0405643
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.040507
LOC112694756 uncharaterized LOC112694756 0.040053
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0399227
FBXL20 F-box and leucine-rich repeat protein 20 0.0398333
HIP1 huntingtin interacting protein 1 0.039801
ENSA endosulfine alpha 0.0393838
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0391924
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0373974
RPL19 ribosomal protein L19 0.0365514
EPB41 erythrocyte membrane protein band 4.1 0.0364877
MRPL13 mitochondrial ribosomal protein L13 0.0364621
EEF2 eukaryotic translation elongation factor 2 0.0356895
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0353068
TLN1 talin 1 0.0347018
RREB1 ras responsive element binding protein 1 0.0346622
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0346438
TRIM24 tripartite motif containing 24 0.0343599
DENND4A DENN/MADD domain containing 4A 0.0342749
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0338211
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0334741
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0334538
LRP12 low density lipoprotein receptor-related protein 12 0.0331851
TMEM135 transmembrane protein 135 0.0329623
MFGE8 milk fat globule-EGF factor 8 protein 0.0329593
SCARB1 scavenger receptor class B, member 1 0.0322965
DLG5 discs, large homolog 5 (Drosophila) 0.03228
TMEM267 transmembrane protein 267 0.030981
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0309332
SQLE squalene epoxidase 0.0308406
ARHGAP6 Rho GTPase activating protein 6 0.030825
CTSD cathepsin D 0.0307329
SSBP3 single stranded DNA binding protein 3 0.0303068
KIAA0319L KIAA0319-like 0.0297189
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0292348
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0289668
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0284026
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.0283938
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0283402
BCAS3 breast carcinoma amplified sequence 3 0.0282614
DENND5A DENN/MADD domain containing 5A 0.0279659
CDK19 cyclin-dependent kinase 19 0.0278767
TAPBP TAP binding protein (tapasin) 0.0278129
RPS24 ribosomal protein S24 0.0277952
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0277232
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.0276552
CNST consortin, connexin sorting protein 0.027651
HBE1 hemoglobin, epsilon 1 0.0275998
RSRP1 arginine/serine-rich protein 1 0.0275219
HBG1 hemoglobin, gamma A 0.0270677
USP34 ubiquitin specific peptidase 34 0.0270298
NCOA1 nuclear receptor coactivator 1 0.0267536
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0261828
RPL30 ribosomal protein L30 0.0261713
STAT5B signal transducer and activator of transcription 5B 0.0261602
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.0261212
SLC44A5 solute carrier family 44, member 5 0.0258598
TRAPPC9 trafficking protein particle complex 9 0.025859
CREBBP CREB binding protein 0.0258296
RPS3 ribosomal protein S3 0.0257877
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.0257099
ATG7 autophagy related 7 0.0256103
LMNA lamin A/C 0.0253891
FTH1 ferritin, heavy polypeptide 1 0.0250843
CORO1C coronin, actin binding protein, 1C 0.0250629
RPL7 ribosomal protein L7 0.0250025
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.0249902
RPL23A ribosomal protein L23a 0.0249797
RPS6 ribosomal protein S6 0.024944
RPLP0 ribosomal protein, large, P0 0.0248807
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0247006
BMP2K BMP2 inducible kinase 0.0246551
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0245023
RPS29 ribosomal protein S29 0.0243354
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0242856
DYM dymeclin 0.0242297
RPL15 ribosomal protein L15 0.0242264
ABHD5 abhydrolase domain containing 5 0.024203
QPRT quinolinate phosphoribosyltransferase 0.024144
PDS5B PDS5 cohesin associated factor B 0.0240784
EPS15 epidermal growth factor receptor pathway substrate 15 0.0240335
RPL14 ribosomal protein L14 0.0238333
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0238274
ARB2A ARB2 cotranscriptional regulator A 0.0237328
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0236603
INSIG1 insulin induced gene 1 0.0235612
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.0233612
ARHGAP24 Rho GTPase activating protein 24 0.0231274
DMXL1 Dmx-like 1 0.0230749
PRKN parkin RBR E3 ubiquitin protein ligase 0.0230533
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 0.0229987
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.0229876
RPS16 ribosomal protein S16 0.0229482
GRIK1 glutamate receptor, ionotropic, kainate 1 0.0228465
CSDE1 cold shock domain containing E1, RNA-binding 0.0228172
FUS FUS RNA binding protein 0.0227527
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 0.0227439
MDK midkine (neurite growth-promoting factor 2) 0.0227407
EXOC2 exocyst complex component 2 0.0226744
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0226364
TRIM56 tripartite motif containing 56 0.0226187
H3-3B H3.3 histone B 0.0221735
ATG10 autophagy related 10 0.0221126
SSH2 slingshot protein phosphatase 2 0.0218832
LRRC58 leucine rich repeat containing 58 0.021842
MECP2 methyl CpG binding protein 2 0.0217214
CFAP70 cilia and flagella associated protein 70 0.0216431
ANAPC16 anaphase promoting complex subunit 16 0.0216362
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0215159
CLCN3 chloride channel, voltage-sensitive 3 0.0210301
NEB nebulin 0.021005
MAPK1 mitogen-activated protein kinase 1 0.0209626
SLC35F5 solute carrier family 35, member F5 0.0209504
AARS1 alanyl-tRNA synthetase 1 0.0207601
SPPL3 signal peptide peptidase like 3 0.0207562
CCND3 cyclin D3 0.0206798
NAV1 neuron navigator 1 0.0206371
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.020563
ATF7IP2 activating transcription factor 7 interacting protein 2 0.020536
LATS1 large tumor suppressor kinase 1 0.0205297
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0204859
RHOT1 ras homolog family member T1 0.0204791
STX8 syntaxin 8 0.0204249
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0204206
CPQ carboxypeptidase Q 0.0204167
DPY19L3 dpy-19-like 3 (C. elegans) 0.0204073
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0204046
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0203827
TNRC18 trinucleotide repeat containing 18 0.0203766
RPL27A ribosomal protein L27a 0.0202618
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0202495
RPL23 ribosomal protein L23 0.0202487
APOE apolipoprotein E 0.0202324
XXYLT1 xyloside xylosyltransferase 1 0.0202186
SPAG9 sperm associated antigen 9 0.0201985
ASXL2 additional sex combs like transcriptional regulator 2 0.0201916
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0201835
CLCN6 chloride channel, voltage-sensitive 6 0.0201038
NBAS neuroblastoma amplified sequence 0.0200286
NONO non-POU domain containing, octamer-binding 0.0200074
RANBP9 RAN binding protein 9 0.0199602
MAST4 microtubule associated serine/threonine kinase family member 4 0.0199362
PDS5A PDS5 cohesin associated factor A 0.0198899
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.0198699
LAMP2 lysosomal-associated membrane protein 2 0.0198504
UVRAG UV radiation resistance associated 0.019755
UNK unkempt family zinc finger 0.019704
KIDINS220 kinase D-interacting substrate, 220kDa 0.0197032
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0197021
USP54 ubiquitin specific peptidase 54 0.0196268
PDLIM5 PDZ and LIM domain 5 0.0196236
KIF13B kinesin family member 13B 0.0196167
CELF2 CUGBP, Elav-like family member 2 0.0196129
TRA2A transformer 2 alpha homolog (Drosophila) 0.0195245
TMEM131 transmembrane protein 131 0.0194216
WDR59 WD repeat domain 59 0.019399
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0193714
GAB3 GRB2-associated binding protein 3 0.0193698
KMT2A lysine (K)-specific methyltransferase 2A 0.0192109
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.0191912
SECISBP2L SECIS binding protein 2-like 0.0191573
THEM4 thioesterase superfamily member 4 0.0191186
PTH2R parathyroid hormone 2 receptor 0.0190666
RPS17 ribosomal protein S17 0.0190503
UBE2B ubiquitin-conjugating enzyme E2B 0.0188693
ANXA4 annexin A4 0.0188382
CD63 CD63 molecule 0.0188275
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0188244
KDM1A lysine (K)-specific demethylase 1A 0.0188087
SUMF1 sulfatase modifying factor 1 0.0187241
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0186969
XPO7 exportin 7 0.0185868
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0185635
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0185434
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0185299
RTL10 retrotransposon Gag like 10 0.0185094
RPL8 ribosomal protein L8 0.018483
STAG2 stromal antigen 2 0.0184706
FNIP2 folliculin interacting protein 2 0.0184639
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0184639
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0182877
SLTM SAFB-like, transcription modulator 0.0182581
RPL18 ribosomal protein L18 0.0181964
CHD9 chromodomain helicase DNA binding protein 9 0.0181694
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0181264
DNAH14 dynein, axonemal, heavy chain 14 0.0180742
AHI1 Abelson helper integration site 1 0.0180148
ELP4 elongator acetyltransferase complex subunit 4 0.018006
NOSTRIN nitric oxide synthase trafficking 0.017941
ADD1 adducin 1 (alpha) 0.0178818
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.0178152
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0178143
SMIM14 small integral membrane protein 14 0.0178049
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.0177364
ABHD2 abhydrolase domain containing 2 0.017714
FOXO3 forkhead box O3 0.0176331
ATP5F1E ATP synthase F1 subunit epsilon 0.0176168
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0175948
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0175227
ALDOC aldolase C, fructose-bisphosphate 0.0175181
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0175056
SLC38A1 solute carrier family 38, member 1 0.0174987
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0174611
ATM ATM serine/threonine kinase 0.0173982
KEL Kell blood group, metallo-endopeptidase 0.0173914
OXCT1 3-oxoacid CoA transferase 1 0.0173176
TLK1 tousled-like kinase 1 0.0173105
REEP6 receptor accessory protein 6 0.0172145
RPS4X ribosomal protein S4, X-linked 0.0171271
RNF24 ring finger protein 24 0.0171198
CPT1A carnitine palmitoyltransferase 1A (liver) 0.0171012
DOK7 docking protein 7 0.0170961
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.0170923
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 0.0170862
ATXN7L1 ataxin 7-like 1 0.0169867
PDCD7 programmed cell death 7 0.0169219
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.0167964
RNF115 ring finger protein 115 0.0167777
HBG2 hemoglobin, gamma G 0.0167584
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0166895
ISYNA1 inositol-3-phosphate synthase 1 0.0166727
MBNL2 muscleblind-like splicing regulator 2 0.0166247
OSBPL9 oxysterol binding protein-like 9 0.0166106
AOPEP aminopeptidase O (putative) 0.0166102
XRN1 5'-3' exoribonuclease 1 0.0165785
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0165724
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.0165562
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0165417
SPAST spastin 0.0165039
UFD1 ubiquitin recognition factor in ER associated degradation 1 0.0164542
TUBA1A tubulin, alpha 1a 0.0164412
PHF21A PHD finger protein 21A 0.016429
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0163482
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.016348
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0163389
PARD3 par-3 family cell polarity regulator 0.0163258
ZSCAN9 zinc finger and SCAN domain containing 9 0.0163034
GSR glutathione reductase 0.0162255
ZNF586 zinc finger protein 586 0.0162209
MYOM1 myomesin 1 0.0162074
RAB21 RAB21, member RAS oncogene family 0.0162046
GOLGA2 golgin A2 0.0161999
REST RE1-silencing transcription factor 0.0161992
DNM1L dynamin 1-like 0.0161571
MVD mevalonate (diphospho) decarboxylase 0.0161099
TBL1X transducin (beta)-like 1X-linked 0.0161073
RPS18 ribosomal protein S18 0.0160869
PTBP2 polypyrimidine tract binding protein 2 0.016048
ATP5PB ATP synthase peripheral stalk-membrane subunit b 0.0160078
DYNLT1 dynein, light chain, Tctex-type 1 0.0159926
TMEM230 transmembrane protein 230 0.0159912
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 0.0159666
TEC tec protein tyrosine kinase 0.0159608
DTNBP1 dystrobrevin binding protein 1 0.0159442
RPL3 ribosomal protein L3 0.0159245
RAB40C RAB40C, member RAS oncogene family 0.0158982
ACD adrenocortical dysplasia homolog (mouse) 0.0158863
JMJD1C jumonji domain containing 1C 0.0158862
TXK TXK tyrosine kinase 0.01586
RICTOR RPTOR independent companion of MTOR, complex 2 0.0157497
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 0.0157065
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.0156708
WDR37 WD repeat domain 37 0.0156619
ZNF431 zinc finger protein 431 0.0156518
EIF1 eukaryotic translation initiation factor 1 0.0156417
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.0156356
PNKD paroxysmal nonkinesigenic dyskinesia 0.0156088
ZNF638 zinc finger protein 638 0.0156009
FASTKD1 FAST kinase domains 1 0.0155605
SEPTIN6 septin 6 0.0155336
SYCP2L synaptonemal complex protein 2-like 0.0154729
PARP1 poly (ADP-ribose) polymerase 1 0.0154634
TENM1 teneurin transmembrane protein 1 0.0154584
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0154539
TAFA2 TAFA chemokine like family member 2 0.0154178
DHCR7 7-dehydrocholesterol reductase 0.0154109
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.0153325
FLOT2 flotillin 2 0.0152372
ACLY ATP citrate lyase 0.0151833
ZNF207 zinc finger protein 207 0.0151713
SPPL2A signal peptide peptidase like 2A 0.0151485
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0151438
CENPP centromere protein P 0.0151391
INTS8 integrator complex subunit 8 0.0150962
SKI SKI proto-oncogene 0.0150957
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.0150698
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.0150439
ACAD10 acyl-CoA dehydrogenase family, member 10 0.0150217
USP48 ubiquitin specific peptidase 48 0.0150079
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0149624
CYTH3 cytohesin 3 0.0149601
NEMF nuclear export mediator factor 0.0149178
KCTD20 potassium channel tetramerization domain containing 20 0.0149149
CD164 CD164 molecule, sialomucin 0.0148771
PXK PX domain containing serine/threonine kinase 0.0148575
JUP junction plakoglobin 0.0148051
ADNP activity-dependent neuroprotector homeobox 0.014659
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 0.0145938
CMC1 C-x(9)-C motif containing 1 0.0145851
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0145614
MFSD11 major facilitator superfamily domain containing 11 0.0145121
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 0.0145056
PSME3IP1 proteasome activator subunit 3 interacting protein 1 0.0144917
PCYOX1 prenylcysteine oxidase 1 0.0144809
MYH10 myosin, heavy chain 10, non-muscle 0.0144705
CBFB core-binding factor, beta subunit 0.014464
ATF5 activating transcription factor 5 0.0144621
SUMO1 small ubiquitin-like modifier 1 0.0144594
GOLGA4 golgin A4 0.0144584
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0144569
UBA2 ubiquitin-like modifier activating enzyme 2 0.0144372
BCL7A B-cell CLL/lymphoma 7A 0.0144
RHOG ras homolog family member G 0.0143937
PDAP1 PDGFA associated protein 1 0.0143703
RPS9 ribosomal protein S9 0.0143687
RPL21 ribosomal protein L21 0.0143541
NEK7 NIMA-related kinase 7 0.0142463
GPR137 G protein-coupled receptor 137 0.0142255
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0142074
RAB6A RAB6A, member RAS oncogene family 0.0142053
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0141945
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0141615
NMRAL1 NmrA-like family domain containing 1 0.0141016
MINDY3 MINDY lysine 48 deubiquitinase 3 0.0140363
DEPDC4 DEP domain containing 4 0.0140085
ADIPOR2 adiponectin receptor 2 0.013969
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 0.0139539
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0139388
TALDO1 transaldolase 1 0.0138591
MYO1D myosin ID 0.013845
SHARPIN SHANK-associated RH domain interactor 0.0138346
PWWP2A PWWP domain containing 2A 0.0138101
CEP57 centrosomal protein 57kDa 0.0138066
RPL10A ribosomal protein L10a 0.0138062
YY1AP1 YY1 associated protein 1 0.0137979
APTX aprataxin 0.0137966
NIPBL Nipped-B homolog (Drosophila) 0.0137481
UBQLN1 ubiquilin 1 0.0136637
VAT1 vesicle amine transport 1 0.0136621
MROH1 maestro heat-like repeat family member 1 0.0136306
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0136291
SLC22A23 solute carrier family 22, member 23 0.0136064
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.0135977
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 0.013582
CFAP161 cilia and flagella associated protein 161 0.0135578
TXNIP thioredoxin interacting protein 0.0135572
ZNF780B zinc finger protein 780B 0.0135562
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0135542
SWI5 SWI5 recombination repair homolog (yeast) 0.0135524
STIM1 stromal interaction molecule 1 0.0135108
PAPOLA poly(A) polymerase alpha 0.0134847
RPS12 ribosomal protein S12 0.0134795
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.013475
MYO1E myosin IE 0.0134463
HCFC1 host cell factor C1 0.0134267
FBXL17 F-box and leucine-rich repeat protein 17 0.0134183
TRIP4 thyroid hormone receptor interactor 4 0.0133928
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.013373
WARS1 tryptophanyl-tRNA synthetase 1 0.0133508
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0133362
ANO10 anoctamin 10 0.0133196
SFTPA2 surfactant protein A2 0.0133184
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.013306
HDAC8 histone deacetylase 8 0.0132905
SLC38A6 solute carrier family 38, member 6 0.0132608
NUP153 nucleoporin 153kDa 0.0132436
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.0132361
ITCH itchy E3 ubiquitin protein ligase 0.0132027
ARF1 ADP-ribosylation factor 1 0.0131701
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.0131621
MTMR14 myotubularin related protein 14 0.0131509
DENND5B DENN/MADD domain containing 5B 0.0131443
RNFT2 ring finger protein, transmembrane 2 0.013133
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.0131277
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.0131263
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0131148
CREB5 cAMP responsive element binding protein 5 0.0130981
NEK1 NIMA-related kinase 1 0.0130883
GSTK1 glutathione S-transferase kappa 1 0.0130872
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.0130843
MLXIP MLX interacting protein 0.0130765
CELF1 CUGBP, Elav-like family member 1 0.0130403
PCNT pericentrin 0.0129935
TXN2 thioredoxin 2 0.0129861
GANAB glucosidase, alpha; neutral AB 0.0129471
PIAS1 protein inhibitor of activated STAT, 1 0.012926
ZNF846 zinc finger protein 846 0.0129087
MED13 mediator complex subunit 13 0.0129059
HIC2 hypermethylated in cancer 2 0.0128894
NALF1 NALCN channel auxiliary factor 1 0.0128742
YIPF2 Yip1 domain family, member 2 0.0128738
TOP2B topoisomerase (DNA) II beta 180kDa 0.0128589
NHSL3 NHS like 3 0.0128285
FAM117A family with sequence similarity 117, member A 0.0128005
PHF19 PHD finger protein 19 0.012793
EIF3G eukaryotic translation initiation factor 3, subunit G 0.0127913
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.0127909
DNM1 dynamin 1 0.0127836
NUB1 negative regulator of ubiquitin-like proteins 1 0.0127786
AACS acetoacetyl-CoA synthetase 0.0127685
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 0.012747
PRICKLE1 prickle homolog 1 (Drosophila) 0.012714
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.0126948
MPZL1 myelin protein zero-like 1 0.0126663
SELENBP1 selenium binding protein 1 0.0126444
COG5 component of oligomeric golgi complex 5 0.0125824
RNF130 ring finger protein 130 0.0125546
ZNF765 zinc finger protein 765 0.0125225
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 0.0124879
CCNI cyclin I 0.0124863
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0124834
H2AC6 H2A clustered histone 6 0.0124825
KATNIP katanin interacting protein 0.0124421
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.012436
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0124221
FER fer (fps/fes related) tyrosine kinase 0.0124213
ZNF804A zinc finger protein 804A 0.0123756
TSLIG3B tRNA splicing ligase complex subunit 3B 0.0123336
SLC38A9 solute carrier family 38, member 9 0.0123079
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.0122899
GLYAT glycine-N-acyltransferase 0.0122625
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0122433
PPP4R1 protein phosphatase 4, regulatory subunit 1 0.0122306
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0122196
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.0122103
RC3H1 ring finger and CCCH-type domains 1 0.0122091
SDCCAG8 serologically defined colon cancer antigen 8 0.0121901
GTF2IRD2B GTF2I repeat domain containing 2B 0.0121858
ATP8B4 ATPase, class I, type 8B, member 4 0.0121795
PRRC2B proline-rich coiled-coil 2B 0.0121795
ZNHIT1 zinc finger, HIT-type containing 1 0.0121638
BLVRB biliverdin reductase B 0.0121576
ZNF655 zinc finger protein 655 0.0121537
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0121228
EXOSC6 exosome component 6 0.0121205
MORC3 MORC family CW-type zinc finger 3 0.0121032
DOK3 docking protein 3 0.0120804
RBM41 RNA binding motif protein 41 0.0120715
CLOCK clock circadian regulator 0.0120665
ZNF706 zinc finger protein 706 0.0120579
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) 0.0120497
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.0120363
MCU mitochondrial calcium uniporter 0.0120098
COG4 component of oligomeric golgi complex 4 0.0120067
KDM2B lysine (K)-specific demethylase 2B 0.0119943
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0119656
ZNFX1 zinc finger, NFX1-type containing 1 0.0119644
TRIM41 tripartite motif containing 41 0.0119423
CRTC3 CREB regulated transcription coactivator 3 0.0119374
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.0119348
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0119265
LPIN1 lipin 1 0.0119258
ERGIC2 ERGIC and golgi 2 0.0119033
ZC3H12C zinc finger CCCH-type containing 12C 0.0118991
TRIR telomerase RNA component interacting RNase 0.0118817
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.0118747
ADNP2 ADNP homeobox 2 0.0118703
OGA O-GlcNAcase 0.0118466
RO60 Ro60, Y RNA binding protein 0.0118367
ZFAND6 zinc finger, AN1-type domain 6 0.0118227
UBB ubiquitin B 0.0118126
RBM12B RNA binding motif protein 12B 0.0118105
NBR1 neighbor of BRCA1 gene 1 0.0118024
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 0.011791
YARS1 tyrosyl-tRNA synthetase 1 0.0117863
KLF1 Kruppel-like factor 1 (erythroid) 0.011781
H4C8 H4 clustered histone 8 0.0117782
HDLBP high density lipoprotein binding protein 0.0117699
COMMD10 COMM domain containing 10 0.0117567
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) 0.0117224

decreased expression

Symbol Name Standardized Value
MAML2 mastermind-like 2 (Drosophila) -0.116577
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0905151
SMYD3 SET and MYND domain containing 3 -0.0828857
ACTN4 actinin, alpha 4 -0.0807065
PRKCA protein kinase C, alpha -0.0805791
FBXL13 F-box and leucine-rich repeat protein 13 -0.079247
MARCHF3 membrane associated ring-CH-type finger 3 -0.0762948
ENO1 enolase 1, (alpha) -0.0757715
DIAPH1 diaphanous-related formin 1 -0.0724178
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0696625
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0662287
CENPF centromere protein F, 350/400kDa -0.0646322
ARL15 ADP-ribosylation factor-like 15 -0.0611325
FGF13 fibroblast growth factor 13 -0.0597664
FHIT fragile histidine triad -0.0589523
KIF13A kinesin family member 13A -0.0570457
MBNL1 muscleblind-like splicing regulator 1 -0.0566863
CNKSR3 CNKSR family member 3 -0.0565497
MKI67 marker of proliferation Ki-67 -0.0564125
TNIK TRAF2 and NCK interacting kinase -0.0547539
MAP4 microtubule-associated protein 4 -0.0533986
PRKCB protein kinase C, beta -0.050986
CALR calreticulin -0.050935
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0507909
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0502878
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.049142
USP15 ubiquitin specific peptidase 15 -0.0487855
CALN1 calneuron 1 -0.0487373
NUP214 nucleoporin 214kDa -0.0481828
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0473062
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0468232
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0449901
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.0448996
GRB2 growth factor receptor-bound protein 2 -0.0443053
FKBP5 FK506 binding protein 5 -0.0437237
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0435943
RHAG Rh-associated glycoprotein -0.0429144
SAMD4A sterile alpha motif domain containing 4A -0.0425588
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0423493
KRT8 keratin 8, type II -0.0420331
PUS7 pseudouridylate synthase 7 (putative) -0.0410002
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0407561
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0403336
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0400783
ECPAS Ecm29 proteasome adaptor and scaffold -0.0398873
KIF14 kinesin family member 14 -0.0392329
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0390601
ARHGAP11B Rho GTPase activating protein 11B -0.0385765
FLNA filamin A, alpha -0.0385686
ANK1 ankyrin 1, erythrocytic -0.0384076
AFG2A AFG2 AAA ATPase homolog A -0.0383816
MSI2 musashi RNA-binding protein 2 -0.0379714
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0375662
FAF1 Fas (TNFRSF6) associated factor 1 -0.0374356
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0368647
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0362269
SCFD2 sec1 family domain containing 2 -0.0358346
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0357127
MEIS2 Meis homeobox 2 -0.0355235
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0351966
PRRC2C proline-rich coiled-coil 2C -0.0348889
TUBB tubulin, beta class I -0.0348804
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0341243
MDN1 MDN1, midasin homolog (yeast) -0.034027
ARHGAP21 Rho GTPase activating protein 21 -0.033368
CHD4 chromodomain helicase DNA binding protein 4 -0.0332881
NCAM2 neural cell adhesion molecule 2 -0.0330527
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0330467
GTF2IRD1 GTF2I repeat domain containing 1 -0.032825
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0327264
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0323821
KMT2C lysine (K)-specific methyltransferase 2C -0.0323229
TASOR2 transcription activation suppressor family member 2 -0.0320653
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0316442
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0316314
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0315852
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0314156
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0310002
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.030805
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0305479
NF1 neurofibromin 1 -0.0300882
EIF5B eukaryotic translation initiation factor 5B -0.0300864
WWC2 WW and C2 domain containing 2 -0.0297986
KIF2C kinesin family member 2C -0.0297747
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.02969
KIAA1958 KIAA1958 -0.0296207
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.0295561
CERS6 ceramide synthase 6 -0.029334
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0291645
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0290917
VMP1 vacuole membrane protein 1 -0.0289389
YEATS2 YEATS domain containing 2 -0.0289374
DCHS2 dachsous cadherin-related 2 -0.0289305
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0285869
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0285784
AGO3 argonaute RISC catalytic component 3 -0.0285192
CDC25C cell division cycle 25C -0.0284873
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0283985
SRRM2 serine/arginine repetitive matrix 2 -0.0282463
STRN3 striatin, calmodulin binding protein 3 -0.0282188
FNDC3B fibronectin type III domain containing 3B -0.0281051
NMU neuromedin U -0.0278784
BCOR BCL6 corepressor -0.0278563
MARCHF7 membrane associated ring-CH-type finger 7 -0.0278517
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0278089
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0274244
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0273159
CDK6 cyclin-dependent kinase 6 -0.0272678
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0271632
FAM168B family with sequence similarity 168, member B -0.0269144
ASPH aspartate beta-hydroxylase -0.0268106
FOXP1 forkhead box P1 -0.0266481
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0265772
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0265754
JARID2 jumonji, AT rich interactive domain 2 -0.0264
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0260783
PLAGL1 pleiomorphic adenoma gene-like 1 -0.02606
ADGRB3 adhesion G protein-coupled receptor B3 -0.026044
UBAC1 UBA domain containing 1 -0.0260093
SRPK1 SRSF protein kinase 1 -0.0259277
PRELID2 PRELI domain containing 2 -0.0258436
CARD11 caspase recruitment domain family, member 11 -0.0257423
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0253096
HPCAL1 hippocalcin-like 1 -0.0252241
SIK3 SIK family kinase 3 -0.0251181
GSE1 Gse1 coiled-coil protein -0.0249716
CLASP1 cytoplasmic linker associated protein 1 -0.024799
CMIP c-Maf inducing protein -0.0244394
MAST2 microtubule associated serine/threonine kinase 2 -0.0243235
TSC22D2 TSC22 domain family, member 2 -0.0242542
KLHDC10 kelch domain containing 10 -0.024254
LIN28B lin-28 homolog B (C. elegans) -0.0241199
CEP170 centrosomal protein 170kDa -0.0240359
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -0.0240065
NFIA nuclear factor I/A -0.0238572
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0238461
MTDH metadherin -0.0237499
IPO7 importin 7 -0.02363
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0236001
BRD4 bromodomain containing 4 -0.0235909
PLCL1 phospholipase C-like 1 -0.0235687
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0232178
GCN1 GCN1 activator of EIF2AK4 -0.0232116
AK1 adenylate kinase 1 -0.0231856
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0231721
RNF217 ring finger protein 217 -0.0231066
PDIA4 protein disulfide isomerase family A, member 4 -0.0230466
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0230437
CEP85L centrosomal protein 85kDa-like -0.0229657
SOS1 son of sevenless homolog 1 (Drosophila) -0.0228564
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0227836
AAK1 AP2 associated kinase 1 -0.0227228
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0226781
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -0.0226066
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0225268
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0225085
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0224202
FBXO11 F-box protein 11 -0.0223913
RORA RAR-related orphan receptor A -0.022377
EXOC6 exocyst complex component 6 -0.0223692
PARK7 parkinson protein 7 -0.0222568
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0222313
RCOR1 REST corepressor 1 -0.0219764
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0218669
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0218296
RHEB Ras homolog enriched in brain -0.0217706
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.0217075
NRIP1 nuclear receptor interacting protein 1 -0.0216905
ADGRE5 adhesion G protein-coupled receptor E5 -0.0215385
KAT6A K(lysine) acetyltransferase 6A -0.0214166
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0213765
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0213464
LIN54 lin-54 DREAM MuvB core complex component -0.0213181
MCM7 minichromosome maintenance complex component 7 -0.0212825
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0212072
SFMBT2 Scm-like with four mbt domains 2 -0.0211501
PDIA6 protein disulfide isomerase family A, member 6 -0.0210879
RRP1B ribosomal RNA processing 1B -0.0210327
LARP1 La ribonucleoprotein domain family, member 1 -0.0208246
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0208131
CTSC cathepsin C -0.0206883
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0205338
RUNX1 runt-related transcription factor 1 -0.020496
RBM15 RNA binding motif protein 15 -0.0204452
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.0203234
ANAPC5 anaphase promoting complex subunit 5 -0.0202205
NUSAP1 nucleolar and spindle associated protein 1 -0.0201645
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0201565
POLH polymerase (DNA directed), eta -0.0201036
RRM1 ribonucleotide reductase M1 -0.0200134
SEC63 SEC63 homolog (S. cerevisiae) -0.0199925
ORC3 origin recognition complex, subunit 3 -0.0199632
CEP85 centrosomal protein 85kDa -0.0199454
QKI QKI, KH domain containing, RNA binding -0.0198647
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.019836
FAM135A family with sequence similarity 135, member A -0.0197144
VARS1 valyl-tRNA synthetase 1 -0.0197003
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0196985
STON2 stonin 2 -0.0196519
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.0196316
KLHL23 kelch-like family member 23 -0.0196271
SMAP2 small ArfGAP2 -0.0196082
ATAD2 ATPase family, AAA domain containing 2 -0.0196015
RBM6 RNA binding motif protein 6 -0.0195308
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.019469
ZNF609 zinc finger protein 609 -0.019398
KIF20B kinesin family member 20B -0.0193738
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0192947
MSN moesin -0.0192485
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0191949
ESRRB estrogen-related receptor beta -0.0191239
WDR43 WD repeat domain 43 -0.0190055
PEAK1 pseudopodium-enriched atypical kinase 1 -0.0189598
RIPOR3 RIPOR family member 3 -0.0188135
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0188006
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0188003
ACOD1 aconitate decarboxylase 1 -0.0187896
UNC13D unc-13 homolog D (C. elegans) -0.0187217
CUL1 cullin 1 -0.0186477
MMS22L MMS22-like, DNA repair protein -0.0186025
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -0.0186007
CCNY cyclin Y -0.0185428
GPHN gephyrin -0.0184555
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0184311
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0184109
SLC35D4 solute carrier family 35 member D4 -0.0183106
CCDC57 coiled-coil domain containing 57 -0.0183027
LIN9 lin-9 DREAM MuvB core complex component -0.0182849
FAM171A1 family with sequence similarity 171, member A1 -0.0182381
MTREX Mtr4 exosome RNA helicase -0.0182107
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0182097
UBP1 upstream binding protein 1 (LBP-1a) -0.0181704
POM121C POM121 transmembrane nucleoporin C -0.0181482
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -0.0181223
ZNF518A zinc finger protein 518A -0.0181018
DYNC2I1 dynein 2 intermediate chain 1 -0.0180476
EML4 echinoderm microtubule associated protein like 4 -0.0180371
FNBP1 formin binding protein 1 -0.0180325
NSD1 nuclear receptor binding SET domain protein 1 -0.0180188
UBE2K ubiquitin-conjugating enzyme E2K -0.018008
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -0.0179792
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.01796
TANGO6 transport and golgi organization 6 homolog (Drosophila) -0.0179595
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0179266
TACC3 transforming, acidic coiled-coil containing protein 3 -0.0178982
ZFR zinc finger RNA binding protein -0.0178558
PICALM phosphatidylinositol binding clathrin assembly protein -0.0178488
MARCHF6 membrane associated ring-CH-type finger 6 -0.0178252
EEA1 early endosome antigen 1 -0.0178202
NUDC nudC nuclear distribution protein -0.0177949
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0177391
CHML choroideremia-like (Rab escort protein 2) -0.0177345
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.0177274
RBBP4 retinoblastoma binding protein 4 -0.0176844
SH2B3 SH2B adaptor protein 3 -0.0176828
PUM3 pumilio RNA binding family member 3 -0.0176577
KHSRP KH-type splicing regulatory protein -0.0176146
TNPO2 transportin 2 -0.0175892
SRP72 signal recognition particle 72kDa -0.0175869
SMC5 structural maintenance of chromosomes 5 -0.0175723
CLIP1 CAP-GLY domain containing linker protein 1 -0.0174643
WDR33 WD repeat domain 33 -0.0174133
KIF2A kinesin heavy chain member 2A -0.0174122
ZNF124 zinc finger protein 124 -0.0174088
PKM pyruvate kinase, muscle -0.0174015
PITRM1 pitrilysin metallopeptidase 1 -0.0173619
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0173041
CLSPN claspin -0.0172696
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0172464
NDC80 NDC80 kinetochore complex component -0.0172093
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0172018
LDHA lactate dehydrogenase A -0.0171556
AKAP11 A kinase (PRKA) anchor protein 11 -0.0171525
RAB10 RAB10, member RAS oncogene family -0.0171354
DOCK8 dedicator of cytokinesis 8 -0.0171191
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0170878
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.017052
ASF1B anti-silencing function 1B histone chaperone -0.0170488
BCLAF1 BCL2-associated transcription factor 1 -0.0170435
HDGF hepatoma-derived growth factor -0.0170128
FUBP1 far upstream element (FUSE) binding protein 1 -0.0170103
ANKRD12 ankyrin repeat domain 12 -0.0170051
PLIN4 perilipin 4 -0.0169642
PPHLN1 periphilin 1 -0.0169408
PDIA3 protein disulfide isomerase family A, member 3 -0.0169237
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0169221
PTK2B protein tyrosine kinase 2 beta -0.0168519
SACK1A scaffolding CK1 anchoring protein A -0.0168442
RNASE3 ribonuclease, RNase A family, 3 -0.0168432
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.016839
MIA3 melanoma inhibitory activity family, member 3 -0.0168334
SKA2 spindle and kinetochore associated complex subunit 2 -0.0168326
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0167512
SMC4 structural maintenance of chromosomes 4 -0.0167402
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0166798
LARP4B La ribonucleoprotein domain family, member 4B -0.0166766
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -0.0166571
CDCA8 cell division cycle associated 8 -0.016584
CCDC138 coiled-coil domain containing 138 -0.016573
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0165585
DOCK9 dedicator of cytokinesis 9 -0.0165356
VASP vasodilator-stimulated phosphoprotein -0.0164677
CCDC91 coiled-coil domain containing 91 -0.0164406
TMEM181 transmembrane protein 181 -0.0164379
RNF157 ring finger protein 157 -0.0164375
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.0164301
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0163875
ZNF789 zinc finger protein 789 -0.0162864
CENPC centromere protein C -0.0162761
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0162201
USP37 ubiquitin specific peptidase 37 -0.016052
TMEM161B transmembrane protein 161B -0.0158328
DNA2 DNA replication helicase/nuclease 2 -0.0157868
DARS1 aspartyl-tRNA synthetase 1 -0.0157861
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0157484
TUBA1B tubulin, alpha 1b -0.0157332
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.0157015
SMC1A structural maintenance of chromosomes 1A -0.01566
EPHB6 EPH receptor B6 -0.015621
DSG2 desmoglein 2 -0.0156064
GATAD2B GATA zinc finger domain containing 2B -0.0155708
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0155645
PLCD1 phospholipase C, delta 1 -0.0155215
RNF213 ring finger protein 213 -0.0154989
CFH complement factor H -0.0154865
GLUL glutamate-ammonia ligase -0.0154855
NUP205 nucleoporin 205kDa -0.0154791
BCL2L1 BCL2-like 1 -0.0154719
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.0154575
GSPT1 G1 to S phase transition 1 -0.0154564
RAB7A RAB7A, member RAS oncogene family -0.0154319
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -0.0153649
DSCAM Down syndrome cell adhesion molecule -0.015331
BICD1 bicaudal D homolog 1 (Drosophila) -0.0152935
CUL3 cullin 3 -0.0152881
SGMS1 sphingomyelin synthase 1 -0.0152687
CLEC16A C-type lectin domain family 16, member A -0.0152507
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.015233
NCOR1 nuclear receptor corepressor 1 -0.0152224
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -0.0151957
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.0151844
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0151347
CENPK centromere protein K -0.0151303
SCG3 secretogranin III -0.0151295
NDC1 NDC1 transmembrane nucleoporin -0.0151158
DPP9 dipeptidyl-peptidase 9 -0.0150939
BLTP2 bridge-like lipid transfer protein family member 2 -0.0150841
YY1 YY1 transcription factor -0.0150639
NGLY1 N-glycanase 1 -0.0150558
SEC24B SEC24 family member B -0.0150478
ANKRD11 ankyrin repeat domain 11 -0.0150444
CASS4 Cas scaffolding protein family member 4 -0.0150187
AKAP8 A kinase (PRKA) anchor protein 8 -0.0149958
MYLIP myosin regulatory light chain interacting protein -0.0149665
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0149442
GTF2I general transcription factor IIi -0.014944
RHOA ras homolog family member A -0.0149049
USP6NL USP6 N-terminal like -0.014903
NUP155 nucleoporin 155kDa -0.0148829
SYMPK symplekin -0.0148579
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0148496
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -0.0148447
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.014835
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0148178
CD46 CD46 molecule, complement regulatory protein -0.0148127
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0148114
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 -0.014796
SEC31A SEC31 homolog A (S. cerevisiae) -0.0147708
THOC1 THO complex 1 -0.0147541
PLEC plectin -0.014742
CD2AP CD2-associated protein -0.0147251
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.014725
LCLAT1 lysocardiolipin acyltransferase 1 -0.0146973
AGO2 argonaute RISC catalytic component 2 -0.0146757
G2E3 G2/M-phase specific E3 ubiquitin protein ligase -0.0146638
AFDN afadin, adherens junction formation factor -0.0146561
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.014643
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0146388
PA2G4 proliferation-associated 2G4, 38kDa -0.0146225
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -0.0145424
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0145317
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.0145242
TRAF3 TNF receptor-associated factor 3 -0.0145044
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0144967
AIG1 androgen-induced 1 -0.0144904
ANKRD28 ankyrin repeat domain 28 -0.0144787
WDR70 WD repeat domain 70 -0.0144766
MAPK14 mitogen-activated protein kinase 14 -0.0144566
ZYG11A zyg-11 family member A, cell cycle regulator -0.0143897
TPX2 TPX2, microtubule-associated -0.0143481
SUGP2 SURP and G patch domain containing 2 -0.0143433
MACF1 microtubule-actin crosslinking factor 1 -0.0142908
NVL nuclear VCP-like -0.0142749
CKAP5 cytoskeleton associated protein 5 -0.0142459
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0141306
WT1 Wilms tumor 1 -0.0141125
ERI3 ERI1 exoribonuclease family member 3 -0.0140642
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0140256
SETD2 SET domain containing 2 -0.0140207
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0140005
FANCI Fanconi anemia, complementation group I -0.0139876
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0139853
ARGLU1 arginine and glutamate rich 1 -0.0139545
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.0139532
CDK13 cyclin-dependent kinase 13 -0.0138916
NRDC nardilysin convertase -0.0138876
PIBF1 progesterone immunomodulatory binding factor 1 -0.0138868
ZNF146 zinc finger protein 146 -0.0138753
STAT5A signal transducer and activator of transcription 5A -0.0138449
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -0.0138099
CTSH cathepsin H -0.0138023
SLF2 SMC5-SMC6 complex localization factor 2 -0.013785
MACROD1 MACRO domain containing 1 -0.0137717
CCDC18 coiled-coil domain containing 18 -0.0137652
PARN poly(A)-specific ribonuclease -0.0137505
UIMC1 ubiquitin interaction motif containing 1 -0.013707
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0136732
TMEM165 transmembrane protein 165 -0.013671
TGFBR3 transforming growth factor, beta receptor III -0.013655
FBL fibrillarin -0.0135645
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.0135637
METTL16 methyltransferase like 16 -0.0135542
DHDDS dehydrodolichyl diphosphate synthase -0.0135413
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0135212
TPR translocated promoter region, nuclear basket protein -0.0134708
FAM13B family with sequence similarity 13, member B -0.0134454
HSPG2 heparan sulfate proteoglycan 2 -0.0134289
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0134207
MCM4 minichromosome maintenance complex component 4 -0.0134187
EIF3I eukaryotic translation initiation factor 3, subunit I -0.0134015
CDC73 cell division cycle 73 -0.0133972
ELOVL5 ELOVL fatty acid elongase 5 -0.0133764
XPO4 exportin 4 -0.013371
ZNF326 zinc finger protein 326 -0.013341
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0133374
PRR16 proline rich 16 -0.0133355
ASXL1 additional sex combs like transcriptional regulator 1 -0.0133352
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.0133205
PDCD11 programmed cell death 11 -0.0133169
PTK2 protein tyrosine kinase 2 -0.0132921
UBE2H ubiquitin-conjugating enzyme E2H -0.0132807
COMMD1 copper metabolism (Murr1) domain containing 1 -0.0132634
PRPF6 pre-mRNA processing factor 6 -0.0132436
BTBD1 BTB (POZ) domain containing 1 -0.0132011
FASN fatty acid synthase -0.0131934
DOCK6 dedicator of cytokinesis 6 -0.0131884
MRPS10 mitochondrial ribosomal protein S10 -0.0131869
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0131703
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 -0.0131689
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.0131665
ZMYND8 zinc finger, MYND-type containing 8 -0.0131401
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -0.0131383
ZNF106 zinc finger protein 106 -0.0131149
FRRS1 ferric-chelate reductase 1 -0.0130949
ARMH3 armadillo like helical domain containing 3 -0.01309
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -0.0130671
SORT1 sortilin 1 -0.01306
ETNK1 ethanolamine kinase 1 -0.013045
DIAPH3 diaphanous-related formin 3 -0.0130236
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0130076
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.0130002
KIF4A kinesin family member 4A -0.0129913
ACVR1 activin A receptor, type I -0.0129801
STK4 serine/threonine kinase 4 -0.0129673
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -0.0129645
NCK1 NCK adaptor protein 1 -0.0129621
WDR12 WD repeat domain 12 -0.0129556
PHB1 prohibitin 1 -0.0129195
ACER3 alkaline ceramidase 3 -0.0128969
GOLM2 golgi membrane protein 2 -0.0128906
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0128028
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.0128017
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0127974
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0127483
UGCG UDP-glucose ceramide glucosyltransferase -0.0127211
TPST2 tyrosylprotein sulfotransferase 2 -0.012714
ATG13 autophagy related 13 -0.0126977
STK38 serine/threonine kinase 38 -0.0126644
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.012637
WDPCP WD repeat containing planar cell polarity effector -0.0125194
FAF2 Fas associated factor family member 2 -0.0125112
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0125042
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -0.0125029
PITPNB phosphatidylinositol transfer protein, beta -0.0124982
SNU13 small nuclear ribonucleoprotein 13 -0.0124823
SLC37A3 solute carrier family 37, member 3 -0.0124714
CCT2 chaperonin containing TCP1, subunit 2 (beta) -0.0124711
OCIAD1 OCIA domain containing 1 -0.0124603
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.0124519
XPO6 exportin 6 -0.0124408
BICRAL BICRA like chromatin remodeling complex associated protein -0.0124406
NUP133 nucleoporin 133kDa -0.0124374
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0124337
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0124122
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0123983
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -0.0123834
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0123706
KLHL18 kelch-like family member 18 -0.0122954
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0122639
NUP54 nucleoporin 54kDa -0.012252