K562_NVP-BSK805 2HCl_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description NVP-BSK805 2HCl 100nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_NVP-BSK805 2HCl_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0967326
ZMYND8 zinc finger, MYND-type containing 8 0.0798427
MED13L mediator complex subunit 13-like 0.0783823
HBG1 hemoglobin, gamma A 0.0766427
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0594201
ENO1 enolase 1, (alpha) 0.0565797
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.0560753
VMP1 vacuole membrane protein 1 0.0557395
UNK unkempt family zinc finger 0.0554613
ZCCHC7 zinc finger, CCHC domain containing 7 0.0552954
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0549414
ATXN2 ataxin 2 0.0536353
LTBP1 latent transforming growth factor beta binding protein 1 0.0534215
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0517484
STRBP spermatid perinuclear RNA binding protein 0.0509538
BIRC6 baculoviral IAP repeat containing 6 0.0503975
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0501428
CENPF centromere protein F, 350/400kDa 0.0492048
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0482297
PTH2R parathyroid hormone 2 receptor 0.0480134
FOXK2 forkhead box K2 0.0471137
RPL28 ribosomal protein L28 0.0470014
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0460179
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0452439
KMT2C lysine (K)-specific methyltransferase 2C 0.0450486
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0447746
NAP1L4 nucleosome assembly protein 1-like 4 0.0443007
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.043835
MUSK muscle, skeletal, receptor tyrosine kinase 0.0434278
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0420062
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0419629
FANCA Fanconi anemia, complementation group A 0.0415506
FLNA filamin A, alpha 0.0414222
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0409218
KNL1 kinetochore scaffold 1 0.0405037
NCAPG2 non-SMC condensin II complex, subunit G2 0.0401787
MICU1 mitochondrial calcium uptake 1 0.0401249
RPS5 ribosomal protein S5 0.0400538
CHD4 chromodomain helicase DNA binding protein 4 0.0399482
ACTG1 actin gamma 1 0.039817
ADAM10 ADAM metallopeptidase domain 10 0.0393821
DIAPH1 diaphanous-related formin 1 0.0392082
LDHA lactate dehydrogenase A 0.038977
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.0389178
ZBTB20 zinc finger and BTB domain containing 20 0.038721
HP1BP3 heterochromatin protein 1, binding protein 3 0.0385096
SRRM2 serine/arginine repetitive matrix 2 0.0383254
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0378288
TGFBR3 transforming growth factor, beta receptor III 0.0377639
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0368271
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) 0.0367317
SREBF2 sterol regulatory element binding transcription factor 2 0.0362746
RNF24 ring finger protein 24 0.0362599
HEATR1 HEAT repeat containing 1 0.0361538
ZNF609 zinc finger protein 609 0.0356597
RSRP1 arginine/serine-rich protein 1 0.0356385
RPS19 ribosomal protein S19 0.0353581
GDNF glial cell derived neurotrophic factor 0.035207
AFG1L AFG1 like ATPase 0.0349695
DCAKD dephospho-CoA kinase domain containing 0.0345062
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0344455
PHACTR4 phosphatase and actin regulator 4 0.034419
EIF3I eukaryotic translation initiation factor 3, subunit I 0.0340916
BMAL2 basic helix-loop-helix ARNT like 2 0.0339726
MYO3B myosin IIIB 0.0336206
RCC2 regulator of chromosome condensation 2 0.0334351
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0331902
RABGAP1L RAB GTPase activating protein 1-like 0.0331093
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0330877
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.033053
DNAAF9 dynein axonemal assembly factor 9 0.0327888
PTBP2 polypyrimidine tract binding protein 2 0.032682
LMNA lamin A/C 0.0326517
ZNF106 zinc finger protein 106 0.032437
KLHL22 kelch-like family member 22 0.0323048
SEC63 SEC63 homolog (S. cerevisiae) 0.0322122
PKP4 plakophilin 4 0.0321233
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0317501
IQGAP2 IQ motif containing GTPase activating protein 2 0.0315884
CMC4 C-x(9)-C motif containing 4 0.0315606
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.0315205
TMEM131 transmembrane protein 131 0.031436
ORC3 origin recognition complex, subunit 3 0.0312961
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.0312396
PRAME preferentially expressed antigen in melanoma 0.0310991
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0309896
EXOC2 exocyst complex component 2 0.030879
HBE1 hemoglobin, epsilon 1 0.0308686
LRP12 low density lipoprotein receptor-related protein 12 0.030864
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.0306846
ESYT2 extended synaptotagmin-like protein 2 0.0306326
RPL12 ribosomal protein L12 0.0306189
KMT2E lysine (K)-specific methyltransferase 2E 0.0306101
E2F3 E2F transcription factor 3 0.030373
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0303448
ZNF496 zinc finger protein 496 0.0303039
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0302347
TBC1D5 TBC1 domain family, member 5 0.0302089
WDR43 WD repeat domain 43 0.0301101
TCF12 transcription factor 12 0.0299618
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.0299361
RPS24 ribosomal protein S24 0.0298686
LOC112694756 uncharaterized LOC112694756 0.0297255
HDLBP high density lipoprotein binding protein 0.0293658
MTDH metadherin 0.0293268
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.029217
CLASP2 cytoplasmic linker associated protein 2 0.029177
TRIP12 thyroid hormone receptor interactor 12 0.029052
TRPS1 trichorhinophalangeal syndrome I 0.0289118
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0288578
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0286659
MEF2C myocyte enhancer factor 2C 0.0286427
HBA1 hemoglobin, alpha 1 0.0286104
CDK19 cyclin-dependent kinase 19 0.0285444
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0284696
USP47 ubiquitin specific peptidase 47 0.0283704
PDLIM5 PDZ and LIM domain 5 0.0282527
CHD7 chromodomain helicase DNA binding protein 7 0.0281921
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0281533
MDN1 MDN1, midasin homolog (yeast) 0.0281479
STXBP1 syntaxin binding protein 1 0.0276336
CEP350 centrosomal protein 350kDa 0.0275984
FAM184A family with sequence similarity 184, member A 0.0275705
TBC1D23 TBC1 domain family, member 23 0.0275536
CLASP1 cytoplasmic linker associated protein 1 0.0274242
EXPH5 exophilin 5 0.0272432
AP1B1 adaptor-related protein complex 1, beta 1 subunit 0.0272289
KMT2A lysine (K)-specific methyltransferase 2A 0.0272017
PDLIM7 PDZ and LIM domain 7 (enigma) 0.0271194
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.0270884
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0270639
MAP2K1 mitogen-activated protein kinase kinase 1 0.0270384
TMEM164 transmembrane protein 164 0.0268992
TJP1 tight junction protein 1 0.0268242
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0267669
ARHGAP11B Rho GTPase activating protein 11B 0.0266479
VIRMA vir like m6A methyltransferase associated 0.0266304
TGFB1 transforming growth factor, beta 1 0.0265555
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.0264829
RAP1A RAP1A, member of RAS oncogene family 0.0264802
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0264151
BRI3BP BRI3 binding protein 0.026412
ZMIZ1 zinc finger, MIZ-type containing 1 0.026303
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 0.0261446
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.0260263
SRRM1 serine/arginine repetitive matrix 1 0.025902
ANGPT1 angiopoietin 1 0.0258628
EEA1 early endosome antigen 1 0.025767
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0257286
GLG1 golgi glycoprotein 1 0.0257128
TPI1 triosephosphate isomerase 1 0.0256925
PARD3 par-3 family cell polarity regulator 0.0256028
MPHOSPH9 M-phase phosphoprotein 9 0.0256004
EGR1 early growth response 1 0.0255131
POLH polymerase (DNA directed), eta 0.0254839
SPOP speckle-type POZ protein 0.0254443
FBXL18 F-box and leucine-rich repeat protein 18 0.0254212
CAPRIN1 cell cycle associated protein 1 0.0253606
FER fer (fps/fes related) tyrosine kinase 0.0253485
SNX1 sorting nexin 1 0.0253428
PCNT pericentrin 0.0253301
ARID1A AT rich interactive domain 1A (SWI-like) 0.0252935
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0252399
RHOG ras homolog family member G 0.0252346
NFE2L2 nuclear factor, erythroid 2-like 2 0.0251615
APLP2 amyloid beta (A4) precursor-like protein 2 0.0251582
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0250275
TMEM267 transmembrane protein 267 0.0249924
ATAD2 ATPase family, AAA domain containing 2 0.0249077
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0248882
ACVR1 activin A receptor, type I 0.0248548
KATNIP katanin interacting protein 0.0248303
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.0247953
CLCN5 chloride channel, voltage-sensitive 5 0.0247782
RAB22A RAB22A, member RAS oncogene family 0.0246861
CAPZB capping protein (actin filament) muscle Z-line, beta 0.024651
ALDOC aldolase C, fructose-bisphosphate 0.0246357
TMOD3 tropomodulin 3 (ubiquitous) 0.0246286
NUP62 nucleoporin 62kDa 0.0244471
H4C8 H4 clustered histone 8 0.0243786
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.024256
SAMD4B sterile alpha motif domain containing 4B 0.0242324
TATDN1 TatD DNase domain containing 1 0.0241819
PCGF6 polycomb group ring finger 6 0.0241408
PHF20 PHD finger protein 20 0.02411
MEIOB meiosis specific with OB domains 0.0240368
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 0.0240341
CELF1 CUGBP, Elav-like family member 1 0.0239685
ATM ATM serine/threonine kinase 0.023935
SNX9 sorting nexin 9 0.023878
GOLGA2 golgin A2 0.0238351
SPPL2A signal peptide peptidase like 2A 0.0238317
ARHGAP5 Rho GTPase activating protein 5 0.0237556
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.023738
BRD4 bromodomain containing 4 0.0237139
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0237039
N4BP2 NEDD4 binding protein 2 0.0236804
UNC13D unc-13 homolog D (C. elegans) 0.0235823
SKA2 spindle and kinetochore associated complex subunit 2 0.0235543
AATF apoptosis antagonizing transcription factor 0.0235468
NOP53 NOP53 ribosome biogenesis factor 0.0233997
COMMD1 copper metabolism (Murr1) domain containing 1 0.0233736
ABHD2 abhydrolase domain containing 2 0.0232686
CSPP1 centrosome and spindle pole associated protein 1 0.0230858
CRTAC1 cartilage acidic protein 1 0.0230423
ISYNA1 inositol-3-phosphate synthase 1 0.0230284
KIF1B kinesin family member 1B 0.0229863
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0229531
WDR20 WD repeat domain 20 0.0229431
WWOX WW domain containing oxidoreductase 0.0229168
MFSD12 major facilitator superfamily domain containing 12 0.0228916
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0228591
NFIA nuclear factor I/A 0.0228266
MAPK6 mitogen-activated protein kinase 6 0.0227632
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.0227348
ECI1 enoyl-CoA delta isomerase 1 0.022687
RBM6 RNA binding motif protein 6 0.022656
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0225247
MAPK8 mitogen-activated protein kinase 8 0.0224605
MKI67 marker of proliferation Ki-67 0.0224048
HBA2 hemoglobin, alpha 2 0.0223799
RPL5 ribosomal protein L5 0.0223102
GATAD2B GATA zinc finger domain containing 2B 0.0222972
YLPM1 YLP motif containing 1 0.022292
ERP29 endoplasmic reticulum protein 29 0.0222783
SPIDR scaffolding protein involved in DNA repair 0.0222573
CNKSR3 CNKSR family member 3 0.0222224
C2CD3 C2 calcium-dependent domain containing 3 0.0222053
WDR33 WD repeat domain 33 0.0222019
SEPTIN6 septin 6 0.0221537
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0221531
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.0221454
TBL1X transducin (beta)-like 1X-linked 0.0221193
C6ORF89 chromosome 6 open reading frame 89 0.0221116
ARHGAP15 Rho GTPase activating protein 15 0.022086
GALK2 galactokinase 2 0.0220777
COQ4 coenzyme Q4 0.0220699
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0220637
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.0219781
RTN4 reticulon 4 0.0219672
ASCC2 activating signal cointegrator 1 complex subunit 2 0.0219032
ELP6 elongator acetyltransferase complex subunit 6 0.0218743
MSH3 mutS homolog 3 0.0218261
RPS8 ribosomal protein S8 0.0217787
GIGYF2 GRB10 interacting GYF protein 2 0.0217686
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.0217117
PUM3 pumilio RNA binding family member 3 0.021687
RAD23B RAD23 homolog B (S. cerevisiae) 0.0216471
YIPF4 Yip1 domain family, member 4 0.0216453
RPL7L1 ribosomal protein L7-like 1 0.021634
WASF2 WAS protein family, member 2 0.0215686
PUM1 pumilio RNA-binding family member 1 0.0214793
CARNMT1 carnosine N-methyltransferase 1 0.0214487
GATD1 glutamine amidotransferase class 1 domain containing 1 0.0214263
PKN1 protein kinase N1 0.0213936
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0213648
CTSD cathepsin D 0.0213342
HSPA8 heat shock 70kDa protein 8 0.0213262
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0212799
SCAF4 SR-related CTD-associated factor 4 0.0211874
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.0211744
HPS5 Hermansky-Pudlak syndrome 5 0.0211321
MKRN1 makorin ring finger protein 1 0.0210013
GMPR guanosine monophosphate reductase 0.0209937
YEATS2 YEATS domain containing 2 0.0209849
RBSN rabenosyn, RAB effector 0.0209675
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 0.0208889
PEAK1 pseudopodium-enriched atypical kinase 1 0.0208703
OLA1 Obg-like ATPase 1 0.0208484
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.0208261
LONP2 lon peptidase 2, peroxisomal 0.0208005
RPL34 ribosomal protein L34 0.0206912
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0206837
ZNF440 zinc finger protein 440 0.0206246
SCAP SREBF chaperone 0.0206009
ZMYM2 zinc finger, MYM-type 2 0.0205676
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.0204881
WDR4 WD repeat domain 4 0.0204477
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.0203676
MTREX Mtr4 exosome RNA helicase 0.0202972
NUCB1 nucleobindin 1 0.020296
PITX1 paired-like homeodomain 1 0.0202943
MYH10 myosin, heavy chain 10, non-muscle 0.0202772
RHBDD2 rhomboid domain containing 2 0.0202566
NCKAP5L NCK-associated protein 5-like 0.0202375
VTA1 vesicle (multivesicular body) trafficking 1 0.0202095
ATXN2L ataxin 2-like 0.0201985
CDC7 cell division cycle 7 0.0201736
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0200906
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 0.0200279
NFXL1 nuclear transcription factor, X-box binding-like 1 0.0200143
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0200112
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.019976
CAPNS1 calpain, small subunit 1 0.0199338
JPT1 Jupiter microtubule associated homolog 1 0.0198426
MARCHF3 membrane associated ring-CH-type finger 3 0.0197781
CEP57L1 centrosomal protein 57kDa-like 1 0.0197637
DGKD diacylglycerol kinase, delta 130kDa 0.0197521
RAD18 RAD18 E3 ubiquitin protein ligase 0.0196712
RAB7A RAB7A, member RAS oncogene family 0.0196446
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.0196325
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.0196197
RBBP6 retinoblastoma binding protein 6 0.0195984
ARLN allregulin 0.0195884
RPL7A ribosomal protein L7a 0.0195853
YAF2 YY1 associated factor 2 0.0195591
SUCO SUN domain containing ossification factor 0.0195227
SCFD2 sec1 family domain containing 2 0.0194959
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0194605
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0194535
SCAF8 SR-related CTD-associated factor 8 0.019389
DNAH14 dynein, axonemal, heavy chain 14 0.0193795
DPP9 dipeptidyl-peptidase 9 0.0193544
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 0.0193253
CCDC18 coiled-coil domain containing 18 0.0193203
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 0.0193197
KAT6B K(lysine) acetyltransferase 6B 0.01921
ZNF207 zinc finger protein 207 0.0191587
CYBRD1 cytochrome b reductase 1 0.0191558
KRTAP11-1 keratin associated protein 11-1 0.0191522
GDI2 GDP dissociation inhibitor 2 0.0191393
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0191168
RBBP5 retinoblastoma binding protein 5 0.0190875
SOS1 son of sevenless homolog 1 (Drosophila) 0.0190636
CENPE centromere protein E, 312kDa 0.0189819
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0189695
SUGP1 SURP and G patch domain containing 1 0.0189547
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0189369
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.0189302
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0189235
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.0188819
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0188767
ARTN artemin 0.0188406
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0188182
CEP162 centrosomal protein 162kDa 0.0188007
NIPAL3 NIPA-like domain containing 3 0.0187235
SMYD3 SET and MYND domain containing 3 0.0187214
GALM galactose mutarotase (aldose 1-epimerase) 0.0187113
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.0186846
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.0186804
FAM20B family with sequence similarity 20, member B 0.0186646
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0186244
TRIM44 tripartite motif containing 44 0.0186177
COLGALT1 collagen beta(1-O)galactosyltransferase 1 0.0186163
FAM133B family with sequence similarity 133, member B 0.0186095
XRRA1 X-ray radiation resistance associated 1 0.0185375
RC3H1 ring finger and CCCH-type domains 1 0.0185317
JAK2 Janus kinase 2 0.0185212
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0184798
RPS23 ribosomal protein S23 0.0184445
SLC35F5 solute carrier family 35, member F5 0.0184359
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.0184259
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.0184184
EMC1 ER membrane protein complex subunit 1 0.0184119
GRAMD1A GRAM domain containing 1A 0.0184099
UBE2H ubiquitin-conjugating enzyme E2H 0.0183811
EEF2 eukaryotic translation elongation factor 2 0.0183555
CSNK1G2 casein kinase 1, gamma 2 0.0183426
AK8 adenylate kinase 8 0.0182839
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0182567
DOCK8 dedicator of cytokinesis 8 0.0182247
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.0181718
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.0181623
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 0.0181606
BCL2L1 BCL2-like 1 0.0181425
KIAA1328 KIAA1328 0.0181076
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 0.0180876
CYB561 cytochrome b561 0.0180811
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0180757
RANBP2 RAN binding protein 2 0.0180702
MYO9B myosin IXB 0.0180636
NSRP1 nuclear speckle splicing regulatory protein 1 0.0180462
TSPAN5 tetraspanin 5 0.0180102
DPY19L1 dpy-19-like 1 (C. elegans) 0.0179891
SRP54 signal recognition particle 54kDa 0.017982
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.0179429
SKIC3 SKI3 subunit of superkiller complex 0.0179411
ITCH itchy E3 ubiquitin protein ligase 0.0179159
ACTN1 actinin, alpha 1 0.0179091
PDS5B PDS5 cohesin associated factor B 0.0179027
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.0178984
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 0.0178932
MYEOV myeloma overexpressed 0.0178283
DAPK1 death-associated protein kinase 1 0.0178177
RNF216 ring finger protein 216 0.0178148
ZNF429 zinc finger protein 429 0.0177961
CIRSR corepressor of RBPJ and splicing regulator 0.0177717
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 0.0177654
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.0177574
ZFYVE9 zinc finger, FYVE domain containing 9 0.0177453
FRYL FRY-like 0.0176986
FUBP1 far upstream element (FUSE) binding protein 1 0.0176947
UBP1 upstream binding protein 1 (LBP-1a) 0.0176744
AKAP12 A kinase (PRKA) anchor protein 12 0.017672
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0176467
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.0176346
SH3D19 SH3 domain containing 19 0.0176287
CDYL chromodomain protein, Y-like 0.0176189
NELFCD negative elongation factor complex member C/D 0.0176085
MELK maternal embryonic leucine zipper kinase 0.0175875
RABL6 RAB, member RAS oncogene family-like 6 0.0175498
RPL29 ribosomal protein L29 0.0175223
C1ORF159 chromosome 1 open reading frame 159 0.0174921
TUBD1 tubulin, delta 1 0.0174906
KIF21A kinesin family member 21A 0.0174891
ZC3H18 zinc finger CCCH-type containing 18 0.0174833
KRT19 keratin 19, type I 0.0174355
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.017435
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.0173911
ZNF451 zinc finger protein 451 0.0173802
VWDE von Willebrand factor D and EGF domains 0.0173653
LBR lamin B receptor 0.0173616
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0173522
RPL32 ribosomal protein L32 0.0173337
SAR1A secretion associated, Ras related GTPase 1A 0.0173206
GGCX gamma-glutamyl carboxylase 0.0173064
XKR3 XK, Kell blood group complex subunit-related family, member 3 0.0173053
MFGE8 milk fat globule-EGF factor 8 protein 0.0173038
MTCH2 mitochondrial carrier 2 0.0173003
AKAP11 A kinase (PRKA) anchor protein 11 0.0172999
NCOA1 nuclear receptor coactivator 1 0.0172575
RPL35A ribosomal protein L35a 0.0171906
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.0170929
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0170842
OXR1 oxidation resistance 1 0.0170068
DROSHA drosha, ribonuclease type III 0.0169809
NT5DC1 5'-nucleotidase domain containing 1 0.016963
NEMF nuclear export mediator factor 0.0169391
NAMPT nicotinamide phosphoribosyltransferase 0.0169132
MBTD1 mbt domain containing 1 0.016905
CYRIB CYFIP related Rac1 interactor B 0.0168886
NT5DC3 5'-nucleotidase domain containing 3 0.0168467
JUP junction plakoglobin 0.0168341
ADAMTSL4 ADAMTS-like 4 0.0167917
MARCHF7 membrane associated ring-CH-type finger 7 0.0167815
KDM7A lysine (K)-specific demethylase 7A 0.0167558
UNC45A unc-45 homolog A (C. elegans) 0.0167433
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 0.016728
ZNF518B zinc finger protein 518B 0.0166885
SIMC1 SUMO-interacting motifs containing 1 0.0166718
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0166176
SPTA1 spectrin, alpha, erythrocytic 1 0.0166173
USP1 ubiquitin specific peptidase 1 0.0165849
WDR70 WD repeat domain 70 0.0165734
CASP8AP2 caspase 8 associated protein 2 0.0165467
RPL13A ribosomal protein L13a 0.0165329
ACO2 aconitase 2, mitochondrial 0.0165193
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.0165157
TTLL10 tubulin tyrosine ligase-like family member 10 0.0164835
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 0.016457
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 0.0164308
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.0164259
CTCF CCCTC-binding factor (zinc finger protein) 0.0164162
MCM10 minichromosome maintenance complex component 10 0.0164126
MCU mitochondrial calcium uniporter 0.0163786
ZBTB41 zinc finger and BTB domain containing 41 0.0163785
LMBRD1 LMBR1 domain containing 1 0.0163703
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0163611
KDM4B lysine (K)-specific demethylase 4B 0.016354
AIG1 androgen-induced 1 0.0163278
BLTP2 bridge-like lipid transfer protein family member 2 0.0162735
ATG2A autophagy related 2A 0.0162395
FLOT1 flotillin 1 0.016229
TTL tubulin tyrosine ligase 0.0162277
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0162249
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.0162162
USP54 ubiquitin specific peptidase 54 0.0162091
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.016192
HIPK2 homeodomain interacting protein kinase 2 0.0161795
SIRAL2 SIR2 antiphage like 2 0.0161681
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 0.0161651
FKBP1A FK506 binding protein 1A, 12kDa 0.0161623
DEPDC5 DEP domain containing 5 0.0161202
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 0.0160912
ZFAND6 zinc finger, AN1-type domain 6 0.016024
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0160201
IARS1 isoleucyl-tRNA synthetase 1 0.0159669
FXYD5 FXYD domain containing ion transport regulator 5 0.0159402
TUFM Tu translation elongation factor, mitochondrial 0.0159075
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0158879
TACC3 transforming, acidic coiled-coil containing protein 3 0.0158611
SIRT1 sirtuin 1 0.0158178
NUP107 nucleoporin 107kDa 0.0158174
FAM178B family with sequence similarity 178, member B 0.0158138
RAB33B RAB33B, member RAS oncogene family 0.0158072
ST7L suppression of tumorigenicity 7 like 0.0158008
SAFB scaffold attachment factor B 0.0157777
STXBP3 syntaxin binding protein 3 0.0157507
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0157494
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.0157257
CPQ carboxypeptidase Q 0.0157237
RRBP1 ribosome binding protein 1 0.0157219
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.0157199
NLK nemo-like kinase 0.0156935
ZNF100 zinc finger protein 100 0.0156712
MORC2 MORC family CW-type zinc finger 2 0.0156516
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0156446
C2CD5 C2 calcium-dependent domain containing 5 0.01564
ABHD3 abhydrolase domain containing 3 0.0156184
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0155337

decreased expression

Symbol Name Standardized Value
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0755826
GSE1 Gse1 coiled-coil protein -0.06778
ARL15 ADP-ribosylation factor-like 15 -0.0669142
ARHGAP21 Rho GTPase activating protein 21 -0.0662502
ACTN4 actinin, alpha 4 -0.0636013
EPB41 erythrocyte membrane protein band 4.1 -0.0613103
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0606019
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0584235
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.05572
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0539172
PRELID2 PRELI domain containing 2 -0.0502389
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0500971
TRIM24 tripartite motif containing 24 -0.0449601
MSI2 musashi RNA-binding protein 2 -0.0449451
ZMYM4 zinc finger, MYM-type 4 -0.0447003
CMIP c-Maf inducing protein -0.0434922
VIM vimentin -0.0434389
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0429465
SRPK2 SRSF protein kinase 2 -0.0421809
SOX6 SRY (sex determining region Y)-box 6 -0.0421249
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0420343
KIF2A kinesin heavy chain member 2A -0.0420113
TMEM245 transmembrane protein 245 -0.0415013
NBAS neuroblastoma amplified sequence -0.0413502
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0412518
PRKCA protein kinase C, alpha -0.0411321
TNRC6B trinucleotide repeat containing 6B -0.0410333
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0410079
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0410041
NUMB numb homolog (Drosophila) -0.040707
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0400993
MRPL13 mitochondrial ribosomal protein L13 -0.0397642
JARID2 jumonji, AT rich interactive domain 2 -0.0393332
RELN reelin -0.0392333
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0385666
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0382454
ANK1 ankyrin 1, erythrocytic -0.0380359
MBNL1 muscleblind-like splicing regulator 1 -0.0379507
KIAA2026 KIAA2026 -0.0378095
STAT5B signal transducer and activator of transcription 5B -0.0376257
EXOC4 exocyst complex component 4 -0.0372504
PDS5A PDS5 cohesin associated factor A -0.0371557
CCNY cyclin Y -0.0371508
CTBP2 C-terminal binding protein 2 -0.0369045
ENOSF1 enolase superfamily member 1 -0.0368094
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.0367996
ANO10 anoctamin 10 -0.0367773
LMBR1 limb development membrane protein 1 -0.0367304
RAB10 RAB10, member RAS oncogene family -0.0365649
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0362931
STAT5A signal transducer and activator of transcription 5A -0.0360506
PHTF2 putative homeodomain transcription factor 2 -0.0359995
SLC38A1 solute carrier family 38, member 1 -0.0357546
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0356421
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0349995
TAC4 tachykinin 4 (hemokinin) -0.0345675
NSD3 nuclear receptor binding SET domain protein 3 -0.0345414
CLTC clathrin, heavy chain (Hc) -0.0343845
ADGRV1 adhesion G protein-coupled receptor V1 -0.0339555
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0337502
PRKCSH protein kinase C substrate 80K-H -0.0335902
OSBPL3 oxysterol binding protein-like 3 -0.0334906
THRAP3 thyroid hormone receptor associated protein 3 -0.0332929
SENP6 SUMO1/sentrin specific peptidase 6 -0.0332737
BPTF bromodomain PHD finger transcription factor -0.0331965
HELZ helicase with zinc finger -0.033193
NCOA3 nuclear receptor coactivator 3 -0.0330871
MON2 MON2 homolog (S. cerevisiae) -0.0330099
PPP1R9B protein phosphatase 1, regulatory subunit 9B -0.0329171
TTC28 tetratricopeptide repeat domain 28 -0.0326898
NMU neuromedin U -0.0326693
FAM193A family with sequence similarity 193, member A -0.032226
ASPH aspartate beta-hydroxylase -0.0321769
USP34 ubiquitin specific peptidase 34 -0.0320144
MAML2 mastermind-like 2 (Drosophila) -0.0319232
CCNI cyclin I -0.0317291
NEBL nebulette -0.0316604
STAU1 staufen double-stranded RNA binding protein 1 -0.0316231
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0312847
KIAA0319L KIAA0319-like -0.030777
USP25 ubiquitin specific peptidase 25 -0.0307665
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0306498
RCOR1 REST corepressor 1 -0.0304698
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0301586
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.030129
PRKCB protein kinase C, beta -0.0300209
EIF4B eukaryotic translation initiation factor 4B -0.0298821
SETD5 SET domain containing 5 -0.0298649
SERP1 stress-associated endoplasmic reticulum protein 1 -0.0297903
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0297846
SRBD1 S1 RNA binding domain 1 -0.0295253
NUP98 nucleoporin 98kDa -0.0293476
ZFPM2 zinc finger protein, FOG family member 2 -0.0292164
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.029061
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0289169
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0289093
NIBAN1 niban apoptosis regulator 1 -0.0287986
ZEB2 zinc finger E-box binding homeobox 2 -0.0287695
VEZT vezatin, adherens junctions transmembrane protein -0.0287107
RPL30 ribosomal protein L30 -0.0286532
ARB2A ARB2 cotranscriptional regulator A -0.0286385
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0285303
GSK3B glycogen synthase kinase 3 beta -0.0284405
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0283293
KIF20B kinesin family member 20B -0.0282826
RPS12 ribosomal protein S12 -0.028281
ZC3HC1 zinc finger, C3HC-type containing 1 -0.0281416
DCAF10 DDB1 and CUL4 associated factor 10 -0.028013
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0279224
ETV6 ets variant 6 -0.0278416
PPA1 pyrophosphatase (inorganic) 1 -0.0278035
DSTYK dual serine/threonine and tyrosine protein kinase -0.0277632
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.027725
VCP valosin containing protein -0.0276873
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0276191
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0275636
MBD5 methyl-CpG binding domain protein 5 -0.0275322
QKI QKI, KH domain containing, RNA binding -0.0275213
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0273242
AHCYL2 adenosylhomocysteinase-like 2 -0.0273173
FAM168A family with sequence similarity 168, member A -0.0271793
TMCC1 transmembrane and coiled-coil domain family 1 -0.0271711
SLA2 Src-like-adaptor 2 -0.0270944
KIF18B kinesin family member 18B -0.0270864
USP32 ubiquitin specific peptidase 32 -0.0270099
NCOR1 nuclear receptor corepressor 1 -0.0269719
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0268802
PARN poly(A)-specific ribonuclease -0.0268164
CCDC91 coiled-coil domain containing 91 -0.0267917
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0266265
CARD11 caspase recruitment domain family, member 11 -0.0265912
FBXO17 F-box protein 17 -0.026574
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0264587
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0264344
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0263985
ATAD2B ATPase family, AAA domain containing 2B -0.0262214
USP24 ubiquitin specific peptidase 24 -0.0261891
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -0.0261039
MLXIP MLX interacting protein -0.0259991
DIDO1 death inducer-obliterator 1 -0.0259176
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0257232
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0257217
MED13 mediator complex subunit 13 -0.0256834
SIK3 SIK family kinase 3 -0.0255347
MAP4 microtubule-associated protein 4 -0.0255256
PUS7 pseudouridylate synthase 7 (putative) -0.0254798
STAG2 stromal antigen 2 -0.0254044
NUP210 nucleoporin 210kDa -0.025232
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.025197
WDR26 WD repeat domain 26 -0.0250944
NOP58 NOP58 ribonucleoprotein -0.0249482
RAB40C RAB40C, member RAS oncogene family -0.0249292
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -0.024854
EMC3 ER membrane protein complex subunit 3 -0.0248354
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.024737
NOL9 nucleolar protein 9 -0.0247148
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -0.0246901
STK38 serine/threonine kinase 38 -0.0246897
TRAK1 trafficking protein, kinesin binding 1 -0.0245873
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0245817
TNPO1 transportin 1 -0.0245451
MOB1B MOB kinase activator 1B -0.0244761
REPS1 RALBP1 associated Eps domain containing 1 -0.0244282
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0243926
TPST2 tyrosylprotein sulfotransferase 2 -0.024345
ATG7 autophagy related 7 -0.0242517
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0242458
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -0.0241113
EXOC6 exocyst complex component 6 -0.0240566
BMP2K BMP2 inducible kinase -0.0240009
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0239803
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0237957
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0235184
TIMELESS timeless circadian clock -0.0234033
XPOT exportin, tRNA -0.0233983
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0233516
SSH2 slingshot protein phosphatase 2 -0.0232555
SCLT1 sodium channel and clathrin linker 1 -0.023243
GANAB glucosidase, alpha; neutral AB -0.0231109
RPSA ribosomal protein SA -0.023079
FBXL13 F-box and leucine-rich repeat protein 13 -0.0230602
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0230281
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0229857
GOLGA4 golgin A4 -0.0229583
CALU calumenin -0.0229572
CFAP251 cilia and flagella associated protein 251 -0.0228708
RPS15 ribosomal protein S15 -0.0227391
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.022705
TXNRD1 thioredoxin reductase 1 -0.0226787
GCN1 GCN1 activator of EIF2AK4 -0.0225733
COPA coatomer protein complex, subunit alpha -0.0225386
TCF25 transcription factor 25 (basic helix-loop-helix) -0.0225275
NVL nuclear VCP-like -0.0225223
ANAPC10 anaphase promoting complex subunit 10 -0.0225111
FAM168B family with sequence similarity 168, member B -0.022469
SARS2 seryl-tRNA synthetase 2, mitochondrial -0.0224454
TANGO2 transport and golgi organization 2 homolog (Drosophila) -0.0224342
TGOLN2 trans-golgi network protein 2 -0.0223976
BTNL9 butyrophilin-like 9 -0.0223772
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0223362
MTFR1 mitochondrial fission regulator 1 -0.022274
ADNP activity-dependent neuroprotector homeobox -0.022229
MYO16 myosin XVI -0.0222156
CDK12 cyclin-dependent kinase 12 -0.0221928
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0220381
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0219478
FNBP4 formin binding protein 4 -0.0219464
RFX7 regulatory factor X, 7 -0.021919
SSH1 slingshot protein phosphatase 1 -0.0218798
ARHGAP12 Rho GTPase activating protein 12 -0.0218398
ELP4 elongator acetyltransferase complex subunit 4 -0.0218276
THADA thyroid adenoma associated -0.0217752
HSF1 heat shock transcription factor 1 -0.0216547
FBXO42 F-box protein 42 -0.0216495
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -0.0216359
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -0.021535
ARHGAP17 Rho GTPase activating protein 17 -0.0214709
FNDC3B fibronectin type III domain containing 3B -0.0214338
RRP1B ribosomal RNA processing 1B -0.0213836
ZFAND3 zinc finger, AN1-type domain 3 -0.021369
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0213639
CD2AP CD2-associated protein -0.021296
TLN1 talin 1 -0.021278
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -0.0212768
TPM3 tropomyosin 3 -0.0212658
RPL14 ribosomal protein L14 -0.0212476
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0211797
RTN3 reticulon 3 -0.0211739
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0210837
CAB39 calcium binding protein 39 -0.0210388
CACUL1 CDK2-associated, cullin domain 1 -0.0209461
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0209419
ARRB1 arrestin, beta 1 -0.0208118
TMEM120B transmembrane protein 120B -0.0207963
PDIA4 protein disulfide isomerase family A, member 4 -0.0207076
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -0.0206988
ATP11A ATPase, class VI, type 11A -0.0206846
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.0206254
AKR1C1 aldo-keto reductase family 1, member C1 -0.0206114
MPV17 MpV17 mitochondrial inner membrane protein -0.0205947
CEP152 centrosomal protein 152kDa -0.0205406
NLN neurolysin (metallopeptidase M3 family) -0.0205173
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -0.0204453
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa -0.0204427
CAVIN1 caveolae associated protein 1 -0.0203745
DPY19L3 dpy-19-like 3 (C. elegans) -0.0203506
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0202939
ATP5MK ATP synthase membrane subunit k -0.0202579
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0202254
NAP1L1 nucleosome assembly protein 1-like 1 -0.020181
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -0.0201655
NRDC nardilysin convertase -0.020165
PCGF3 polycomb group ring finger 3 -0.02012
VDAC2 voltage-dependent anion channel 2 -0.0200937
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0200908
RSF1 remodeling and spacing factor 1 -0.0200696
BICD1 bicaudal D homolog 1 (Drosophila) -0.0200258
DYM dymeclin -0.0200227
TEX2 testis expressed 2 -0.0200096
PRRC2A proline-rich coiled-coil 2A -0.019911
OCIAD1 OCIA domain containing 1 -0.019889
GAN gigaxonin -0.0198269
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0197929
ZCCHC8 zinc finger, CCHC domain containing 8 -0.0197502
CCDC137 coiled-coil domain containing 137 -0.0197177
CTR9 CTR9, Paf1/RNA polymerase II complex component -0.0197046
DNPEP aspartyl aminopeptidase -0.0196621
MAU2 MAU2 sister chromatid cohesion factor -0.0196154
ENSA endosulfine alpha -0.0195438
MED15 mediator complex subunit 15 -0.0195068
CAMKMT calmodulin-lysine N-methyltransferase -0.0195031
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0193996
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0193995
RNF121 ring finger protein 121 -0.0193082
IQCB1 IQ motif containing B1 -0.0192875
BIN3 bridging integrator 3 -0.019285
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0192804
IPO7 importin 7 -0.0192569
DNM1L dynamin 1-like -0.0192299
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0191829
ATP13A3 ATPase type 13A3 -0.019109
MAPK1 mitogen-activated protein kinase 1 -0.0190415
NUP153 nucleoporin 153kDa -0.0190266
GATA2 GATA binding protein 2 -0.0189785
CDK13 cyclin-dependent kinase 13 -0.0189623
TTC27 tetratricopeptide repeat domain 27 -0.0189539
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -0.0189419
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0188547
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.0188511
TRIM27 tripartite motif containing 27 -0.0188479
SEC24A SEC24 family member A -0.0188209
FBXL20 F-box and leucine-rich repeat protein 20 -0.0187647
RPAP2 RNA polymerase II associated protein 2 -0.0187613
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -0.0187434
BSG basigin (Ok blood group) -0.0187284
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.0187061
WWC2 WW and C2 domain containing 2 -0.0186804
GGPS1 geranylgeranyl diphosphate synthase 1 -0.0186694
FKBP14 FK506 binding protein 14, 22 kDa -0.0186453
DENND5A DENN/MADD domain containing 5A -0.018624
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0186206
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.018597
CLIP1 CAP-GLY domain containing linker protein 1 -0.0185332
DMD dystrophin -0.0184536
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.0184534
PDCD11 programmed cell death 11 -0.018441
NUP155 nucleoporin 155kDa -0.0184406
CASS4 Cas scaffolding protein family member 4 -0.0184308
STXBP4 syntaxin binding protein 4 -0.0184263
RCSD1 RCSD domain containing 1 -0.0184049
ATP5F1C ATP synthase F1 subunit gamma -0.0184025
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0183841
MED27 mediator complex subunit 27 -0.0183789
LIN28B lin-28 homolog B (C. elegans) -0.01835
DCAF17 DDB1 and CUL4 associated factor 17 -0.0183414
RUFY2 RUN and FYVE domain containing 2 -0.0183026
HMGN1 high mobility group nucleosome binding domain 1 -0.018279
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.018273
CANX calnexin -0.0182534
ZNF804B zinc finger protein 804B -0.0182285
YIPF6 Yip1 domain family, member 6 -0.0182184
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0182177
AGO1 argonaute RISC catalytic component 1 -0.0182116
GLUL glutamate-ammonia ligase -0.0181842
BRCA1 breast cancer 1, early onset -0.0181822
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0181653
LIMA1 LIM domain and actin binding 1 -0.0181387
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0180492
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -0.0179838
LDAH lipid droplet associated hydrolase -0.0179757
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.017954
C6ORF62 chromosome 6 open reading frame 62 -0.0179522
PHAX phosphorylated adaptor for RNA export -0.017923
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0179162
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.0178596
FLNB filamin B, beta -0.0178474
WTAP Wilms tumor 1 associated protein -0.0177943
TFCP2 transcription factor CP2 -0.0177778
KIFC3 kinesin family member C3 -0.0177472
VARS1 valyl-tRNA synthetase 1 -0.0176962
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0176788
SEPTIN9 septin 9 -0.0176732
DCAF6 DDB1 and CUL4 associated factor 6 -0.0176263
FDPS farnesyl diphosphate synthase -0.0176156
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -0.0175703
TRAPPC10 trafficking protein particle complex 10 -0.0175331
COASY CoA synthase -0.0175257
ZNF280B zinc finger protein 280B -0.0174938
APRT adenine phosphoribosyltransferase -0.0174535
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0173936
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0173769
CDC27 cell division cycle 27 -0.0173635
SEC24B SEC24 family member B -0.0173284
ADAM17 ADAM metallopeptidase domain 17 -0.0173018
DEPDC1B DEP domain containing 1B -0.0172895
QRICH1 glutamine-rich 1 -0.0172713
EDARADD EDAR-associated death domain -0.0172511
TM9SF4 transmembrane 9 superfamily protein member 4 -0.0172435
GTF2IRD1 GTF2I repeat domain containing 1 -0.0172404
ELAVL1 ELAV like RNA binding protein 1 -0.0172049
CEP295 centrosomal protein 295kDa -0.0171708
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0170475
KEL Kell blood group, metallo-endopeptidase -0.0169708
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0169039
SATB2 SATB homeobox 2 -0.0168781
PDIA6 protein disulfide isomerase family A, member 6 -0.0168619
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0168499
RPS2 ribosomal protein S2 -0.0168315
CDC123 cell division cycle 123 -0.016806
GPATCH8 G patch domain containing 8 -0.0167652
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -0.0167432
ZNF611 zinc finger protein 611 -0.0167301
NCAM2 neural cell adhesion molecule 2 -0.0167197
PIAS1 protein inhibitor of activated STAT, 1 -0.0167188
RPL22 ribosomal protein L22 -0.0167047
PHF3 PHD finger protein 3 -0.0167008
STON2 stonin 2 -0.0166936
KRT18 keratin 18, type I -0.0166579
MPZL1 myelin protein zero-like 1 -0.0166556
BLTP1 bridge-like lipid transfer protein family member 1 -0.0166418
CCM2 cerebral cavernous malformation 2 -0.0166406
FOXN2 forkhead box N2 -0.0165964
SMAP2 small ArfGAP2 -0.0165955
OTUD4 OTU deubiquitinase 4 -0.0165644
NPEPPS aminopeptidase puromycin sensitive -0.0165387
KARS1 lysyl-tRNA synthetase 1 -0.0165373
MMS22L MMS22-like, DNA repair protein -0.0164339
NME7 NME/NM23 family member 7 -0.016433
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0164237
STK4 serine/threonine kinase 4 -0.0164153
HPS1 Hermansky-Pudlak syndrome 1 -0.0163997
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.0163774
DMGDH dimethylglycine dehydrogenase -0.0163433
TAPBP TAP binding protein (tapasin) -0.0163226
CASC3 cancer susceptibility candidate 3 -0.0163222
MASTL microtubule associated serine/threonine kinase-like -0.0163208
NR2F6 nuclear receptor subfamily 2, group F, member 6 -0.0163145
SRP72 signal recognition particle 72kDa -0.0162913
WDFY3 WD repeat and FYVE domain containing 3 -0.0162677
SNX2 sorting nexin 2 -0.0162553
GMEB1 glucocorticoid modulatory element binding protein 1 -0.0162497
EXT2 exostosin glycosyltransferase 2 -0.0162487
RHOC ras homolog family member C -0.0162482
NUP188 nucleoporin 188kDa -0.0162116
HSPA4 heat shock 70kDa protein 4 -0.0161972
RHOBTB3 Rho-related BTB domain containing 3 -0.0161839
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.0161506
GOLM2 golgi membrane protein 2 -0.0161449
MAP1S microtubule-associated protein 1S -0.0161173
PRR16 proline rich 16 -0.0161136
UBE3D ubiquitin protein ligase E3D -0.0161112
CATSPERB catsper channel auxiliary subunit beta -0.016109
DENND1A DENN/MADD domain containing 1A -0.016082
PKNOX1 PBX/knotted 1 homeobox 1 -0.0160582
GINM1 glycoprotein integral membrane 1 -0.0160447
POTEF POTE ankyrin domain family, member F -0.0160419
DCHS2 dachsous cadherin-related 2 -0.0160334
ZNHIT6 zinc finger, HIT-type containing 6 -0.0160316
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.0160312
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0160223
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0160048
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.0159832
SERGEF secretion regulating guanine nucleotide exchange factor -0.0159803
EGFL7 EGF-like-domain, multiple 7 -0.0159694
VEGFB vascular endothelial growth factor B -0.0159652
SNX5 sorting nexin 5 -0.0159586
CENPP centromere protein P -0.0159582
GDE1 glycerophosphodiester phosphodiesterase 1 -0.0159331
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0159231
ARHGAP18 Rho GTPase activating protein 18 -0.0159133
SPPL3 signal peptide peptidase like 3 -0.0158682
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0158591
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.015843
DGCR2 DiGeorge syndrome critical region gene 2 -0.0158123
AK1 adenylate kinase 1 -0.0158088
ZFR zinc finger RNA binding protein -0.0158025
WDR1 WD repeat domain 1 -0.0157817
CMTR1 cap methyltransferase 1 -0.01576
COX19 COX19 cytochrome c oxidase assembly factor -0.0157539
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0157525
UVRAG UV radiation resistance associated -0.0157416
ZNF592 zinc finger protein 592 -0.0156813
RFC3 replication factor C (activator 1) 3, 38kDa -0.0156667
ARHGAP42 Rho GTPase activating protein 42 -0.0156576
CERS2 ceramide synthase 2 -0.015639
WAPL WAPL cohesin release factor -0.0156247
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -0.01562
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0156171
DGCR8 DGCR8 microprocessor complex subunit -0.0156094
MDM4 MDM4, p53 regulator -0.0156093
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0155933
LAS1L LAS1-like (S. cerevisiae) -0.0155867
TMEM181 transmembrane protein 181 -0.0155862
GRID1 glutamate receptor, ionotropic, delta 1 -0.0155415
FGD6 FYVE, RhoGEF and PH domain containing 6 -0.0155365
CD46 CD46 molecule, complement regulatory protein -0.0155
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 -0.0154534
NFYC nuclear transcription factor Y, gamma -0.0154435
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.0153614
CALCOCO2 calcium binding and coiled-coil domain 2 -0.0153339
RHOT1 ras homolog family member T1 -0.0153254
GK5 glycerol kinase 5 (putative) -0.0153055
H3-3A H3.3 histone A -0.0152638
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0152419
BCORL1 BCL6 corepressor-like 1 -0.0152329
ICE2 interactor of little elongation complex ELL subunit 2 -0.0151922
PTMA prothymosin, alpha -0.0151745
POU2F1 POU class 2 homeobox 1 -0.0151134
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0151132
SZRD1 SUZ RNA binding domain containing 1 -0.0150725
MAP7 microtubule-associated protein 7 -0.0150523
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0150193
LRP10 low density lipoprotein receptor-related protein 10 -0.0150043
RAB11A RAB11A, member RAS oncogene family -0.0149786
PANK3 pantothenate kinase 3 -0.0149671
ACLY ATP citrate lyase -0.0149453
LRP6 low density lipoprotein receptor-related protein 6 -0.0149187
TFAM transcription factor A, mitochondrial -0.0149007
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.014898
ATP5MC3 ATP synthase membrane subunit c locus 3 -0.0148745
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0148471
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0148274
GIPR gastric inhibitory polypeptide receptor -0.0148265
TSLIG1 tRNA splicing ligase complex subunit 1 -0.0148251
CYB5R3 cytochrome b5 reductase 3 -0.0148231
RPL27A ribosomal protein L27a -0.0148133
NGLY1 N-glycanase 1 -0.014792
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -0.0147801
MDC1 mediator of DNA-damage checkpoint 1 -0.0147702
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -0.0147579
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0147475
RDX radixin -0.0147148
WIPI2 WD repeat domain, phosphoinositide interacting 2 -0.0147063
PLA2G12A phospholipase A2, group XIIA -0.0146907
UBE2O ubiquitin-conjugating enzyme E2O -0.0146892
BRIX1 BRX1, biogenesis of ribosomes -0.0146838
PRPF6 pre-mRNA processing factor 6 -0.014648
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -0.0146319
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0146269
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -0.0146222