K562_NVP-BSK805 2HCl_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description NVP-BSK805 2HCl 10nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_NVP-BSK805 2HCl_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PLCL1 phospholipase C-like 1 0.076901
GAB2 GRB2-associated binding protein 2 0.0706196
USP32 ubiquitin specific peptidase 32 0.0696643
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0694763
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0685944
LARP1 La ribonucleoprotein domain family, member 1 0.0622132
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0582721
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0581378
SRPK2 SRSF protein kinase 2 0.0568742
COMT catechol-O-methyltransferase 0.0530244
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0521561
BLVRB biliverdin reductase B 0.051589
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0514131
NUP214 nucleoporin 214kDa 0.0513743
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0510993
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.0496542
PDE4D phosphodiesterase 4D, cAMP-specific 0.0495243
NBAS neuroblastoma amplified sequence 0.0491246
MUSK muscle, skeletal, receptor tyrosine kinase 0.0490938
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0489465
NKTR natural killer cell triggering receptor 0.0488804
NOL10 nucleolar protein 10 0.0467065
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0466881
XPO1 exportin 1 0.0464948
PDIA6 protein disulfide isomerase family A, member 6 0.0461983
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0451255
MAML2 mastermind-like 2 (Drosophila) 0.043746
R3HDM1 R3H domain containing 1 0.0432813
CEP350 centrosomal protein 350kDa 0.043015
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0427024
USP34 ubiquitin specific peptidase 34 0.0423265
MED13L mediator complex subunit 13-like 0.0418805
DIAPH1 diaphanous-related formin 1 0.0418585
LARP4B La ribonucleoprotein domain family, member 4B 0.0410981
CHD9 chromodomain helicase DNA binding protein 9 0.0407601
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0398832
POGZ pogo transposable element with ZNF domain 0.0397713
RORA RAR-related orphan receptor A 0.0393394
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0392793
IARS1 isoleucyl-tRNA synthetase 1 0.0392438
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0392206
PRAME preferentially expressed antigen in melanoma 0.0391731
PCM1 pericentriolar material 1 0.0390175
ENSA endosulfine alpha 0.0386973
KDM6A lysine (K)-specific demethylase 6A 0.0386566
PRKCSH protein kinase C substrate 80K-H 0.0385538
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0385135
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.038447
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.038402
COG5 component of oligomeric golgi complex 5 0.0381648
SMC6 structural maintenance of chromosomes 6 0.0381625
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.0380848
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.0379008
PTPRA protein tyrosine phosphatase, receptor type, A 0.0375564
TUBA1B tubulin, alpha 1b 0.0374485
BCL2L1 BCL2-like 1 0.0373458
ESYT2 extended synaptotagmin-like protein 2 0.0371851
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0371515
STX8 syntaxin 8 0.0369565
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0366436
XPO4 exportin 4 0.036472
DNPEP aspartyl aminopeptidase 0.0363085
ZCCHC7 zinc finger, CCHC domain containing 7 0.0358642
EXOC4 exocyst complex component 4 0.0358137
CARS1 cysteinyl-tRNA synthetase 1 0.0355963
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0354519
SPG11 spastic paraplegia 11 (autosomal recessive) 0.035437
RPS18 ribosomal protein S18 0.0352049
SFMBT2 Scm-like with four mbt domains 2 0.0348468
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0348157
NUMB numb homolog (Drosophila) 0.0347767
KDM5A lysine (K)-specific demethylase 5A 0.0346138
PHIP pleckstrin homology domain interacting protein 0.0344036
IPP intracisternal A particle-promoted polypeptide 0.034397
TMEM120B transmembrane protein 120B 0.03433
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0341943
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0337945
LAMP2 lysosomal-associated membrane protein 2 0.0337737
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0335408
AARS1 alanyl-tRNA synthetase 1 0.0333834
CHD4 chromodomain helicase DNA binding protein 4 0.0333666
RC3H1 ring finger and CCCH-type domains 1 0.0332675
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.0332345
RPL37A ribosomal protein L37a 0.0329908
PICALM phosphatidylinositol binding clathrin assembly protein 0.0328328
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.0327493
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0327273
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0324702
KIDINS220 kinase D-interacting substrate, 220kDa 0.0324376
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0323078
HBA1 hemoglobin, alpha 1 0.0322709
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.0321996
TP53BP1 tumor protein p53 binding protein 1 0.0321958
EIF4B eukaryotic translation initiation factor 4B 0.0321187
ANKRD28 ankyrin repeat domain 28 0.0320244
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0319663
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0319561
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0317502
AHI1 Abelson helper integration site 1 0.0316146
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0315539
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0314599
FNBP4 formin binding protein 4 0.0313202
CDCP1 CUB domain containing protein 1 0.0312144
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0311588
VIM vimentin 0.0310776
UHMK1 U2AF homology motif (UHM) kinase 1 0.0307763
HBA2 hemoglobin, alpha 2 0.0306502
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0306156
SOS2 son of sevenless homolog 2 (Drosophila) 0.0306137
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0303931
USP9X ubiquitin specific peptidase 9, X-linked 0.0303885
ATG7 autophagy related 7 0.0303589
MYADM myeloid-associated differentiation marker 0.0301353
GMDS GDP-mannose 4,6-dehydratase 0.0300915
RSRP1 arginine/serine-rich protein 1 0.0299543
TMOD3 tropomodulin 3 (ubiquitous) 0.029941
NUP153 nucleoporin 153kDa 0.0298573
KAT6A K(lysine) acetyltransferase 6A 0.0298249
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0298205
RPL32 ribosomal protein L32 0.029768
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.0296092
MPG N-methylpurine-DNA glycosylase 0.0293776
HOMER1 homer scaffolding protein 1 0.029356
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.0292863
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0289938
HM13 histocompatibility (minor) 13 0.0286377
CDC14A cell division cycle 14A 0.0285712
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.0285527
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.028445
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.0281299
RPS27 ribosomal protein S27 0.0280883
FAM120A family with sequence similarity 120A 0.0279226
NFXL1 nuclear transcription factor, X-box binding-like 1 0.0279141
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0278615
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.0278246
PLD3 phospholipase D family, member 3 0.0275907
STRN striatin, calmodulin binding protein 0.0275723
KYNU kynureninase 0.0272017
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.0270485
RAD51C RAD51 paralog C 0.0270416
CMIP c-Maf inducing protein 0.0270132
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0269398
SSBP2 single-stranded DNA binding protein 2 0.0267633
PEAK1 pseudopodium-enriched atypical kinase 1 0.0267093
RLF rearranged L-myc fusion 0.0266452
TP53 tumor protein p53 0.026626
MTDH metadherin 0.0266232
TXNRD1 thioredoxin reductase 1 0.0265806
CCDC91 coiled-coil domain containing 91 0.0265673
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.0265509
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0265438
MON2 MON2 homolog (S. cerevisiae) 0.0262892
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0262688
LEPROT leptin receptor overlapping transcript 0.0261922
LDAH lipid droplet associated hydrolase 0.0261142
CALN1 calneuron 1 0.026069
SMC4 structural maintenance of chromosomes 4 0.0260643
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0259692
MKI67 marker of proliferation Ki-67 0.0259535
KIF13A kinesin family member 13A 0.0259512
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.0259088
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0258628
FASTKD1 FAST kinase domains 1 0.0258017
HBG2 hemoglobin, gamma G 0.0257565
SDCCAG8 serologically defined colon cancer antigen 8 0.0256348
TUG1 taurine up-regulated 1 (non-protein coding) 0.0256157
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.0254986
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.0253629
PCNT pericentrin 0.0252496
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0252195
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0252104
PRKCB protein kinase C, beta 0.0247681
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0247003
XRN1 5'-3' exoribonuclease 1 0.0246721
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0245853
LARP1B La ribonucleoprotein domain family, member 1B 0.0245775
FANCA Fanconi anemia, complementation group A 0.0245049
RPL37 ribosomal protein L37 0.024494
TAGLN2 transgelin 2 0.0244142
KMT2C lysine (K)-specific methyltransferase 2C 0.0243908
PDS5B PDS5 cohesin associated factor B 0.0243871
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 0.0243851
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.0242851
ESRRB estrogen-related receptor beta 0.0241449
EEA1 early endosome antigen 1 0.0241344
DESI2 desumoylating isopeptidase 2 0.0241274
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0239987
WRN Werner syndrome, RecQ helicase-like 0.0239468
GCLC glutamate-cysteine ligase, catalytic subunit 0.0239096
SSH2 slingshot protein phosphatase 2 0.0238575
FHIT fragile histidine triad 0.023774
CCDC88A coiled-coil domain containing 88A 0.0237598
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0237437
ATP5F1A ATP synthase F1 subunit alpha 0.0236653
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 0.0235304
GCN1 GCN1 activator of EIF2AK4 0.0234907
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0234699
ADGRV1 adhesion G protein-coupled receptor V1 0.0233767
RSBN1 round spermatid basic protein 1 0.0233258
BICRAL BICRA like chromatin remodeling complex associated protein 0.0233076
BLTP2 bridge-like lipid transfer protein family member 2 0.0232951
CENPP centromere protein P 0.0232691
TMEM164 transmembrane protein 164 0.0232577
KIAA2026 KIAA2026 0.0232298
MTMR1 myotubularin related protein 1 0.0232067
ATP5PB ATP synthase peripheral stalk-membrane subunit b 0.0231956
ITGAV integrin, alpha V 0.0231793
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.0231471
WDR62 WD repeat domain 62 0.0231214
OGA O-GlcNAcase 0.0231099
HBE1 hemoglobin, epsilon 1 0.0230786
CEPT1 choline/ethanolamine phosphotransferase 1 0.0230147
LIMK1 LIM domain kinase 1 0.0229907
EIF3D eukaryotic translation initiation factor 3, subunit D 0.0229898
SND1 staphylococcal nuclease and tudor domain containing 1 0.0228985
STK40 serine/threonine kinase 40 0.0227981
ZNF235 zinc finger protein 235 0.0227858
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0227325
BRD1 bromodomain containing 1 0.0227142
CSDE1 cold shock domain containing E1, RNA-binding 0.0226901
ANK1 ankyrin 1, erythrocytic 0.0226741
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 0.022618
NRDC nardilysin convertase 0.0226084
BAIAP2 BAI1-associated protein 2 0.0225913
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.0224793
ZC3H13 zinc finger CCCH-type containing 13 0.0224787
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.022455
RYBP RING1 and YY1 binding protein 0.0224517
MPHOSPH9 M-phase phosphoprotein 9 0.0223943
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0223693
RPS6 ribosomal protein S6 0.0223134
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0222965
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0222385
MLXIP MLX interacting protein 0.0222338
TRAPPC9 trafficking protein particle complex 9 0.0221887
KIFC3 kinesin family member C3 0.0221717
MAPK1 mitogen-activated protein kinase 1 0.0221147
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0221037
SEM1 SEM1 26S proteasome subunit 0.0220919
SIL1 SIL1 nucleotide exchange factor 0.0220623
SCAND3 SCAN domain containing 3 0.0220146
RPS9 ribosomal protein S9 0.0220003
EEF2 eukaryotic translation elongation factor 2 0.021904
TSC22D4 TSC22 domain family, member 4 0.0218132
SCAMP2 secretory carrier membrane protein 2 0.0217703
MAPK14 mitogen-activated protein kinase 14 0.0217026
RNF213 ring finger protein 213 0.0216589
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0214951
SYMPK symplekin 0.0214951
KIF18B kinesin family member 18B 0.0214821
ARID4B AT rich interactive domain 4B (RBP1-like) 0.021467
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.021431
GLG1 golgi glycoprotein 1 0.0213863
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0213323
LIN9 lin-9 DREAM MuvB core complex component 0.0213116
BLMH bleomycin hydrolase 0.0212528
FBL fibrillarin 0.0212294
EIF4E eukaryotic translation initiation factor 4E 0.0212267
SRRM1 serine/arginine repetitive matrix 1 0.0212162
GOLM2 golgi membrane protein 2 0.0211235
SMC3 structural maintenance of chromosomes 3 0.0211109
TLK1 tousled-like kinase 1 0.0211007
RPS5 ribosomal protein S5 0.0210634
ECHDC1 ethylmalonyl-CoA decarboxylase 1 0.0210548
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0209305
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0208314
CYRIB CYFIP related Rac1 interactor B 0.0208138
RNF24 ring finger protein 24 0.0207939
TMEM44 transmembrane protein 44 0.0207935
ANAPC1 anaphase promoting complex subunit 1 0.0207881
ZNF586 zinc finger protein 586 0.0207519
SPC25 SPC25, NDC80 kinetochore complex component 0.0207226
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.0207018
TMCO1 transmembrane and coiled-coil domains 1 0.0206396
CREM cAMP responsive element modulator 0.0206151
BRD7 bromodomain containing 7 0.0205095
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0204364
WNK1 WNK lysine deficient protein kinase 1 0.0204334
RHOA ras homolog family member A 0.0204224
RAB27A RAB27A, member RAS oncogene family 0.0204215
LSR lipolysis stimulated lipoprotein receptor 0.0204072
STX12 syntaxin 12 0.0203396
CHPT1 choline phosphotransferase 1 0.0203117
RPS14 ribosomal protein S14 0.0202028
ZBTB4 zinc finger and BTB domain containing 4 0.0201954
BTBD9 BTB (POZ) domain containing 9 0.0201719
CMTR1 cap methyltransferase 1 0.020153
STEAP1B STEAP family member 1B 0.0199745
TTC27 tetratricopeptide repeat domain 27 0.0199045
MORC2 MORC family CW-type zinc finger 2 0.0199045
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.0198553
LAPTM4B lysosomal protein transmembrane 4 beta 0.0198067
HDLBP high density lipoprotein binding protein 0.0198019
KLHL20 kelch-like family member 20 0.0197901
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.0197873
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.0197621
CCDC125 coiled-coil domain containing 125 0.0197525
TACC3 transforming, acidic coiled-coil containing protein 3 0.0197153
ECI2 enoyl-CoA delta isomerase 2 0.0197089
ADCY8 adenylate cyclase 8 (brain) 0.019689
LUC7L LUC7-like (S. cerevisiae) 0.0196855
GATAD2A GATA zinc finger domain containing 2A 0.0194312
BRD9 bromodomain containing 9 0.0194199
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0193922
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.0193888
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.019383
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 0.019377
MRPL20 mitochondrial ribosomal protein L20 0.0193421
PPP1R21 protein phosphatase 1, regulatory subunit 21 0.0192185
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.0192077
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0191905
NCOA2 nuclear receptor coactivator 2 0.0191548
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 0.019154
ATXN2L ataxin 2-like 0.0191242
ARTN artemin 0.0191239
EHBP1 EH domain binding protein 1 0.0191124
FAM222B family with sequence similarity 222, member B 0.019061
SP3 Sp3 transcription factor 0.0190392
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0190006
DENND4A DENN/MADD domain containing 4A 0.0189969
CDK17 cyclin-dependent kinase 17 0.018894
RRM1 ribonucleotide reductase M1 0.0188684
NABP1 nucleic acid binding protein 1 0.0188505
RPL10A ribosomal protein L10a 0.0188216
LRRC8B leucine rich repeat containing 8 family, member B 0.0188089
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.0187674
GRAP2 GRB2-related adaptor protein 2 0.0187512
MFSD12 major facilitator superfamily domain containing 12 0.0187489
ZFYVE28 zinc finger, FYVE domain containing 28 0.0187487
ELP4 elongator acetyltransferase complex subunit 4 0.0187175
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0186644
QSER1 glutamine and serine rich 1 0.0186629
RANBP2 RAN binding protein 2 0.0185567
KMT2E lysine (K)-specific methyltransferase 2E 0.0185472
RPS23 ribosomal protein S23 0.018546
CHD1L chromodomain helicase DNA binding protein 1-like 0.0185166
CDK8 cyclin-dependent kinase 8 0.0184502
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.0184057
USP12 ubiquitin specific peptidase 12 0.0183854
CCSER2 coiled-coil serine-rich protein 2 0.0183837
CUL5 cullin 5 0.0183672
NUP54 nucleoporin 54kDa 0.0183171
SENP1 SUMO1/sentrin specific peptidase 1 0.0182885
ATAD1 ATPase family, AAA domain containing 1 0.0182281
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.018221
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.0182025
MEF2A myocyte enhancer factor 2A 0.0181821
FBH1 F-box DNA helicase 1 0.0181046
NMT1 N-myristoyltransferase 1 0.0180957
ELMOD3 ELMO/CED-12 domain containing 3 0.0180907
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0180861
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.0180686
DUT deoxyuridine triphosphatase 0.0180656
AVL9 AVL9 homolog (S. cerevisiase) 0.0179725
ASXL1 additional sex combs like transcriptional regulator 1 0.017921
CASS4 Cas scaffolding protein family member 4 0.0179038
SORT1 sortilin 1 0.0178588
DNAH8 dynein, axonemal, heavy chain 8 0.0178301
EIF3K eukaryotic translation initiation factor 3, subunit K 0.0177939
TMEM192 transmembrane protein 192 0.0177514
TUFM Tu translation elongation factor, mitochondrial 0.0177488
MBTD1 mbt domain containing 1 0.017744
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0177051
RHOG ras homolog family member G 0.0176961
FOXO3 forkhead box O3 0.0176496
MPC2 mitochondrial pyruvate carrier 2 0.0175914
CC2D1A coiled-coil and C2 domain containing 1A 0.0175772
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.0175569
PTPRC protein tyrosine phosphatase, receptor type, C 0.0175525
INTS7 integrator complex subunit 7 0.017549
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.0174834
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0174732
IKBIP IKBKB interacting protein 0.0174591
UBAP1 ubiquitin associated protein 1 0.0174569
NCAPD3 non-SMC condensin II complex, subunit D3 0.0174378
IQCE IQ motif containing E 0.0174102
FRS2 fibroblast growth factor receptor substrate 2 0.0174099
MTUS1 microtubule associated tumor suppressor 1 0.0174025
TMEM63A transmembrane protein 63A 0.017373
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.0173725
DMGDH dimethylglycine dehydrogenase 0.0173541
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0173516
FOXP1 forkhead box P1 0.0173406
BAIAP2L1 BAI1-associated protein 2-like 1 0.0173333
MASTL microtubule associated serine/threonine kinase-like 0.0173322
ZNF496 zinc finger protein 496 0.0173071
NEBL nebulette 0.017298
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.0172834
CTSA cathepsin A 0.0172674
LOXL2 lysyl oxidase-like 2 0.0172219
TRIM66 tripartite motif containing 66 0.0172019
PARPBP PARP1 binding protein 0.0171699
MBD5 methyl-CpG binding domain protein 5 0.0171514
SACS sacsin molecular chaperone 0.0171404
SACK1D scaffolding CK1 anchoring protein D 0.017139
ACIN1 apoptotic chromatin condensation inducer 1 0.0171291
CLSTN1 calsyntenin 1 0.0170805
NUMA1 nuclear mitotic apparatus protein 1 0.017057
MAP7 microtubule-associated protein 7 0.0170567
SEC24C SEC24 family member C 0.0170515
HOMER2 homer scaffolding protein 2 0.0170198
MINK1 misshapen-like kinase 1 0.0170141
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.0170048
BRWD3 bromodomain and WD repeat domain containing 3 0.0169863
SQSTM1 sequestosome 1 0.0169845
STON2 stonin 2 0.0169718
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0169565
RCSD1 RCSD domain containing 1 0.0169453
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.016938
RCL1 RNA terminal phosphate cyclase-like 1 0.0169025
UBN2 ubinuclein 2 0.0168899
CA12 carbonic anhydrase XII 0.0168822
ZNF791 zinc finger protein 791 0.0168691
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0168542
FRMD4A FERM domain containing 4A 0.016847
DEK DEK proto-oncogene 0.0167996
RPL4 ribosomal protein L4 0.0167632
BMP2K BMP2 inducible kinase 0.0167479
POT1 protection of telomeres 1 0.016728
ZFAND6 zinc finger, AN1-type domain 6 0.0167259
ATP5MK ATP synthase membrane subunit k 0.0167112
THSD4 thrombospondin, type I, domain containing 4 0.0166753
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 0.0166388
STIM1 stromal interaction molecule 1 0.0165847
PFN1 profilin 1 0.0165819
TMEM41A transmembrane protein 41A 0.0165798
WWOX WW domain containing oxidoreductase 0.016556
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.0165528
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0165497
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0165493
AKAP11 A kinase (PRKA) anchor protein 11 0.0165393
FOXN2 forkhead box N2 0.0164895
MICU2 mitochondrial calcium uptake 2 0.0164819
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.0164721
FNIP1 folliculin interacting protein 1 0.0164535
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0164506
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0164431
ZNF573 zinc finger protein 573 0.0164426
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 0.0164319
NOL8 nucleolar protein 8 0.0164139
MACROD1 MACRO domain containing 1 0.0163923
PARP1 poly (ADP-ribose) polymerase 1 0.0163877
BAG2 BCL2-associated athanogene 2 0.0163388
LYRM4 LYR motif containing 4 0.0163279
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 0.0162913
AQR aquarius intron-binding spliceosomal factor 0.0162607
SCG3 secretogranin III 0.0162588
EVI5 ecotropic viral integration site 5 0.0162315
DSN1 DSN1, MIS12 kinetochore complex component 0.0162286
RPL23 ribosomal protein L23 0.0162224
GDF15 growth differentiation factor 15 0.0162211
RASA2 RAS p21 protein activator 2 0.0161698
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0161389
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0161335
DCAF5 DDB1 and CUL4 associated factor 5 0.0161248
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.0161191
PGK1 phosphoglycerate kinase 1 0.0161145
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.0160852
SEC11A SEC11 homolog A (S. cerevisiae) 0.0160778
CATSPERB catsper channel auxiliary subunit beta 0.0160657
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.0160494
TNPO3 transportin 3 0.0160466
UFSP2 UFM1-specific peptidase 2 0.0160391
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.0160348
CEP170 centrosomal protein 170kDa 0.0160158
TPST2 tyrosylprotein sulfotransferase 2 0.0159942
SAP130 Sin3A-associated protein, 130kDa 0.0159739
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0159317
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0159122
COL4A5 collagen, type IV, alpha 5 0.0159114
TEX9 testis expressed 9 0.015894
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.0158931
XXYLT1 xyloside xylosyltransferase 1 0.0158881
LONP1 lon peptidase 1, mitochondrial 0.0158801
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.0158534
ZDHHC14 zinc finger, DHHC-type containing 14 0.0158496
NLN neurolysin (metallopeptidase M3 family) 0.0158421
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0158286
ACBD3 acyl-CoA binding domain containing 3 0.0158179
TAPT1 transmembrane anterior posterior transformation 1 0.0158099
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.0157651
ZFR zinc finger RNA binding protein 0.0157525
KIF22 kinesin family member 22 0.0157491
TUBB6 tubulin, beta 6 class V 0.0157452
NOSTRIN nitric oxide synthase trafficking 0.0157438
ABTB3 ankyrin repeat and BTB domain containing 3 0.0157375
PRRC2B proline-rich coiled-coil 2B 0.0157232
MGA MGA, MAX dimerization protein 0.0157053
METTL16 methyltransferase like 16 0.0156983
RPLP1 ribosomal protein, large, P1 0.0156478
RFESD Rieske (Fe-S) domain containing 0.0156428
ABR active BCR-related 0.015625
H3C4 H3 clustered histone 4 0.0156126
SLC35H1 solute carrier family 35 member H1 0.0155976
AGTPBP1 ATP/GTP binding protein 1 0.0155768
SNX6 sorting nexin 6 0.0155663
WAPL WAPL cohesin release factor 0.0155621
MYO3B myosin IIIB 0.0155541
ABHD3 abhydrolase domain containing 3 0.0155499
EPN2 epsin 2 0.0155371

decreased expression

Symbol Name Standardized Value
MBNL1 muscleblind-like splicing regulator 1 -0.0717426
TNIK TRAF2 and NCK interacting kinase -0.0683729
SMYD3 SET and MYND domain containing 3 -0.0655275
PRKCA protein kinase C, alpha -0.0646424
ZMYND8 zinc finger, MYND-type containing 8 -0.0591593
ZFPM2 zinc finger protein, FOG family member 2 -0.0569106
FGF13 fibroblast growth factor 13 -0.0557926
DNM2 dynamin 2 -0.0549452
GSE1 Gse1 coiled-coil protein -0.0539292
KIF2A kinesin heavy chain member 2A -0.0503572
PUM2 pumilio RNA-binding family member 2 -0.0502365
CCDC57 coiled-coil domain containing 57 -0.0464846
STRN3 striatin, calmodulin binding protein 3 -0.0462413
AMBRA1 autophagy/beclin-1 regulator 1 -0.0448524
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0438738
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0431862
PRRC2C proline-rich coiled-coil 2C -0.0430775
NCOA3 nuclear receptor coactivator 3 -0.0426664
ARID1A AT rich interactive domain 1A (SWI-like) -0.0424194
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0423615
GOLGA4 golgin A4 -0.0421693
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0416127
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0402487
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0395309
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.0392495
RPTOR regulatory associated protein of MTOR, complex 1 -0.0390577
KDM5B lysine (K)-specific demethylase 5B -0.0390341
CUX1 cut-like homeobox 1 -0.0388964
DMD dystrophin -0.0387637
CCND3 cyclin D3 -0.0386762
CELF1 CUGBP, Elav-like family member 1 -0.0383207
ECPAS Ecm29 proteasome adaptor and scaffold -0.0381231
NUP210 nucleoporin 210kDa -0.0380073
SLC39A11 solute carrier family 39, member 11 -0.0375152
CNTNAP2 contactin associated protein-like 2 -0.037406
SCARB1 scavenger receptor class B, member 1 -0.0373204
ADGRE2 adhesion G protein-coupled receptor E2 -0.0370293
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0369493
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.036891
SCFD2 sec1 family domain containing 2 -0.0365662
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0362907
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0359769
FAF1 Fas (TNFRSF6) associated factor 1 -0.0357268
FDPS farnesyl diphosphate synthase -0.035638
DARS1 aspartyl-tRNA synthetase 1 -0.0355402
FBXL20 F-box and leucine-rich repeat protein 20 -0.0352538
RPS8 ribosomal protein S8 -0.0349616
HPCAL1 hippocalcin-like 1 -0.0347685
ARHGAP11B Rho GTPase activating protein 11B -0.0347549
DYNC2I1 dynein 2 intermediate chain 1 -0.0345883
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0345482
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 -0.0344971
SLC35F5 solute carrier family 35, member F5 -0.034299
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0342556
MED13 mediator complex subunit 13 -0.0340666
HIP1 huntingtin interacting protein 1 -0.0339388
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.033931
RBM6 RNA binding motif protein 6 -0.0338525
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0336522
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0336384
SUSD1 sushi domain containing 1 -0.0336294
RCOR1 REST corepressor 1 -0.0335854
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0334446
MYO1D myosin ID -0.0333035
SACK1A scaffolding CK1 anchoring protein A -0.0329105
HIPK2 homeodomain interacting protein kinase 2 -0.0326717
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0323834
ZEB2 zinc finger E-box binding homeobox 2 -0.0323337
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0322977
MEF2C myocyte enhancer factor 2C -0.0320173
CLASP2 cytoplasmic linker associated protein 2 -0.0317596
ETV6 ets variant 6 -0.0315237
SSBP3 single stranded DNA binding protein 3 -0.0314254
AFF1 AF4/FMR2 family, member 1 -0.0312026
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0311135
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0311104
DCAF6 DDB1 and CUL4 associated factor 6 -0.0310728
SBNO1 strawberry notch homolog 1 (Drosophila) -0.0308852
CLTC clathrin, heavy chain (Hc) -0.0307887
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0307336
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0306537
CERS6 ceramide synthase 6 -0.0306464
CBX5 chromobox homolog 5 -0.0306254
TTC3 tetratricopeptide repeat domain 3 -0.0305012
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0305005
TMEM135 transmembrane protein 135 -0.0303466
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0303225
MEIS2 Meis homeobox 2 -0.0302926
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0300908
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0298621
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0298614
HLTF helicase-like transcription factor -0.0296554
TNPO1 transportin 1 -0.029595
RHOT1 ras homolog family member T1 -0.0294077
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0293296
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0292945
RPS2 ribosomal protein S2 -0.0292296
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0291149
KIAA1958 KIAA1958 -0.0290179
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0289957
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0289115
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.028673
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0286703
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0284631
GLUL glutamate-ammonia ligase -0.0282093
JMJD1C jumonji domain containing 1C -0.0281736
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0280264
MBNL2 muscleblind-like splicing regulator 2 -0.0280256
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0280146
CR1L complement component (3b/4b) receptor 1-like -0.0280091
MAP1B microtubule-associated protein 1B -0.0277861
SRSF4 serine/arginine-rich splicing factor 4 -0.0277144
CDC42SE2 CDC42 small effector 2 -0.0276425
TFRC transferrin receptor -0.0274723
SNAP29 synaptosomal-associated protein, 29kDa -0.0273953
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0272799
TRAPPC12 trafficking protein particle complex 12 -0.0270877
USP8 ubiquitin specific peptidase 8 -0.0270257
ZC3H4 zinc finger CCCH-type containing 4 -0.0269959
KIAA1328 KIAA1328 -0.0269835
PHTF1 putative homeodomain transcription factor 1 -0.0269031
NOP58 NOP58 ribonucleoprotein -0.0269008
TUSC3 tumor suppressor candidate 3 -0.0268063
ARRB1 arrestin, beta 1 -0.026618
LNPK lunapark, ER junction formation factor -0.0265312
NFYC nuclear transcription factor Y, gamma -0.0264371
AATF apoptosis antagonizing transcription factor -0.0263378
MACF1 microtubule-actin crosslinking factor 1 -0.0263272
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0262759
WASF2 WAS protein family, member 2 -0.0262262
SERP1 stress-associated endoplasmic reticulum protein 1 -0.0262123
PARK7 parkinson protein 7 -0.0262042
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0261172
PDCD11 programmed cell death 11 -0.0260171
PPARD peroxisome proliferator-activated receptor delta -0.0260021
TPI1 triosephosphate isomerase 1 -0.0258234
SGMS1 sphingomyelin synthase 1 -0.0258006
AAK1 AP2 associated kinase 1 -0.0257707
SLTM SAFB-like, transcription modulator -0.0257624
FAM168B family with sequence similarity 168, member B -0.0255742
RSF1 remodeling and spacing factor 1 -0.0255222
KIF2C kinesin family member 2C -0.025493
RABL6 RAB, member RAS oncogene family-like 6 -0.0253224
NVL nuclear VCP-like -0.024992
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0248816
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0248704
PKP4 plakophilin 4 -0.0248179
ADD3 adducin 3 (gamma) -0.02454
CBR4 carbonyl reductase 4 -0.0245001
SETD5 SET domain containing 5 -0.0244867
CREBBP CREB binding protein -0.0244766
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0244155
USP24 ubiquitin specific peptidase 24 -0.0244032
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -0.0243909
KRT8 keratin 8, type II -0.0243571
RPS11 ribosomal protein S11 -0.0243557
MRPS18B mitochondrial ribosomal protein S18B -0.0243079
FOXK2 forkhead box K2 -0.0243065
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0242975
NDE1 nudE neurodevelopment protein 1 -0.0242798
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0242377
PTGES2 prostaglandin E synthase 2 -0.0242195
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.0242014
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.024159
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.024152
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0241488
ZNF83 zinc finger protein 83 -0.0240934
ELOVL6 ELOVL fatty acid elongase 6 -0.0240552
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0239675
CDYL chromodomain protein, Y-like -0.0239498
FAM178B family with sequence similarity 178, member B -0.0239322
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0238867
MRTFA myocardin related transcription factor A -0.0236541
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.023594
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta -0.0235808
IPO9 importin 9 -0.023536
AHCTF1 AT hook containing transcription factor 1 -0.0235316
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -0.0235096
ANAPC5 anaphase promoting complex subunit 5 -0.0234867
MCM3 minichromosome maintenance complex component 3 -0.0234544
GSK3B glycogen synthase kinase 3 beta -0.0234061
SNX3 sorting nexin 3 -0.0233844
ZNF611 zinc finger protein 611 -0.023353
CDK13 cyclin-dependent kinase 13 -0.0230672
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0230452
ZBTB20 zinc finger and BTB domain containing 20 -0.0230103
SNX9 sorting nexin 9 -0.0229802
KDM1A lysine (K)-specific demethylase 1A -0.022919
PKN3 protein kinase N3 -0.0229077
TTC28 tetratricopeptide repeat domain 28 -0.0228882
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -0.0227524
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0227269
TMEM181 transmembrane protein 181 -0.0226254
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0224806
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.0224752
KIF1B kinesin family member 1B -0.0224163
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0224131
RNF4 ring finger protein 4 -0.0224086
TLN1 talin 1 -0.0223604
PPHLN1 periphilin 1 -0.0223441
NCOA4 nuclear receptor coactivator 4 -0.0223338
KRT19 keratin 19, type I -0.02229
EVL Enah/Vasp-like -0.0222496
TCP1 t-complex 1 -0.0221479
CSNK1A1 casein kinase 1, alpha 1 -0.0221059
INTS6 integrator complex subunit 6 -0.0220444
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0218132
TGFB1 transforming growth factor, beta 1 -0.0218069
GK5 glycerol kinase 5 (putative) -0.0218049
ARL8B ADP-ribosylation factor-like 8B -0.021795
PNISR PNN-interacting serine/arginine-rich protein -0.0217108
SEPTIN9 septin 9 -0.0216741
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0216488
AGO3 argonaute RISC catalytic component 3 -0.0216034
SH2B3 SH2B adaptor protein 3 -0.0215982
MARCHF6 membrane associated ring-CH-type finger 6 -0.0214865
SPAG9 sperm associated antigen 9 -0.0214329
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.021415
JAK1 Janus kinase 1 -0.0213583
CEP295 centrosomal protein 295kDa -0.0212972
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0212913
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0212336
SENP7 SUMO1/sentrin specific peptidase 7 -0.021212
FBXO34 F-box protein 34 -0.0212112
TXNRD2 thioredoxin reductase 2 -0.0212001
MMS22L MMS22-like, DNA repair protein -0.0211835
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0211694
NT5C2 5'-nucleotidase, cytosolic II -0.0211628
TTC21B tetratricopeptide repeat domain 21B -0.0211316
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -0.0211023
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0210498
USP36 ubiquitin specific peptidase 36 -0.0210483
MADD MAP-kinase activating death domain -0.0209969
ATP5MC3 ATP synthase membrane subunit c locus 3 -0.0209694
WDR45 WD repeat domain 45 -0.0209515
SRP72 signal recognition particle 72kDa -0.0209483
CREB5 cAMP responsive element binding protein 5 -0.0209475
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.0209164
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -0.0208564
PROC protein C (inactivator of coagulation factors Va and VIIIa) -0.0208245
TSC22D2 TSC22 domain family, member 2 -0.0206908
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -0.0206749
ZC3H12C zinc finger CCCH-type containing 12C -0.0206719
ANKRD17 ankyrin repeat domain 17 -0.0206707
PRDX2 peroxiredoxin 2 -0.0206316
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.0205996
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.0205128
TUBB tubulin, beta class I -0.020491
ZNF215 zinc finger protein 215 -0.0204895
PCDHB16 protocadherin beta 16 -0.0204872
HBG1 hemoglobin, gamma A -0.0204646
UBE2H ubiquitin-conjugating enzyme E2H -0.020453
CFH complement factor H -0.0204036
PTBP3 polypyrimidine tract binding protein 3 -0.0203951
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0203923
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0203603
MCPH1 microcephalin 1 -0.0202698
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0202696
EMC3 ER membrane protein complex subunit 3 -0.0202169
GPATCH8 G patch domain containing 8 -0.0202047
CSPP1 centrosome and spindle pole associated protein 1 -0.0201541
SRPK1 SRSF protein kinase 1 -0.0201526
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0201512
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma -0.0201345
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.02011
SEH1L SEH1-like (S. cerevisiae) -0.0201023
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0200841
RHEB Ras homolog enriched in brain -0.0199487
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0198718
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0198176
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.019782
PIBF1 progesterone immunomodulatory binding factor 1 -0.0197621
MZT2A mitotic spindle organizing protein 2A -0.0197456
SREBF2 sterol regulatory element binding transcription factor 2 -0.0197441
NFIA nuclear factor I/A -0.0196607
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.019568
WDR43 WD repeat domain 43 -0.0195566
NPEPPS aminopeptidase puromycin sensitive -0.0194701
TBC1D14 TBC1 domain family, member 14 -0.0194539
SIK3 SIK family kinase 3 -0.0194527
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0194419
ITSN1 intersectin 1 (SH3 domain protein) -0.0194023
FAR1 fatty acyl CoA reductase 1 -0.0193719
LDLR low density lipoprotein receptor -0.0193649
NAP1L1 nucleosome assembly protein 1-like 1 -0.0193631
MYO16 myosin XVI -0.0193151
EDARADD EDAR-associated death domain -0.0192811
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -0.0192673
RAB6A RAB6A, member RAS oncogene family -0.0192656
UCK2 uridine-cytidine kinase 2 -0.0192045
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.0191856
MECP2 methyl CpG binding protein 2 -0.0191572
EGFL7 EGF-like-domain, multiple 7 -0.0190831
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0190752
CAPN7 calpain 7 -0.0190591
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.0190236
RAI14 retinoic acid induced 14 -0.0190039
ERICH1 glutamate-rich 1 -0.0189439
BRWD1 bromodomain and WD repeat domain containing 1 -0.0189141
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0189054
LATS1 large tumor suppressor kinase 1 -0.0188498
NPC1 Niemann-Pick disease, type C1 -0.0188444
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -0.0188358
FBXW11 F-box and WD repeat domain containing 11 -0.0188288
TMEM87A transmembrane protein 87A -0.0188176
ANKRD11 ankyrin repeat domain 11 -0.0188055
CLIC4 chloride intracellular channel 4 -0.0187764
LPIN1 lipin 1 -0.0187414
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0187281
CLIC2 chloride intracellular channel 2 -0.0187196
GDNF glial cell derived neurotrophic factor -0.0186744
METTL8 methyltransferase like 8 -0.018657
MRPS27 mitochondrial ribosomal protein S27 -0.018597
SRBD1 S1 RNA binding domain 1 -0.0185898
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0185861
MTMR2 myotubularin related protein 2 -0.0185609
SCFD1 sec1 family domain containing 1 -0.0185195
RO60 Ro60, Y RNA binding protein -0.0185104
VDAC2 voltage-dependent anion channel 2 -0.0184949
UBE3D ubiquitin protein ligase E3D -0.0184927
SP100 SP100 nuclear antigen -0.0184759
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0184729
AKIRIN1 akirin 1 -0.0184369
SEPTIN6 septin 6 -0.0184142
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0183706
CTBP2 C-terminal binding protein 2 -0.0183412
HIC2 hypermethylated in cancer 2 -0.0183151
RBMX RNA binding motif protein, X-linked -0.0183143
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -0.0182801
MROH1 maestro heat-like repeat family member 1 -0.0182311
VCL vinculin -0.0182233
GALK2 galactokinase 2 -0.0182216
SFT2D1 SFT2 domain containing 1 -0.0181894
FBXL2 F-box and leucine-rich repeat protein 2 -0.018172
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.018154
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0181078
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -0.0180809
PTBP1 polypyrimidine tract binding protein 1 -0.0180684
NUP62 nucleoporin 62kDa -0.0180545
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0180236
PTRH2 peptidyl-tRNA hydrolase 2 -0.0180026
YDJC YdjC homolog (bacterial) -0.0179981
BTBD7 BTB (POZ) domain containing 7 -0.0179749
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.0179284
ERP44 endoplasmic reticulum protein 44 -0.0178856
CBX3 chromobox homolog 3 -0.0178832
SAMD4A sterile alpha motif domain containing 4A -0.0178574
TANGO2 transport and golgi organization 2 homolog (Drosophila) -0.0178407
HSPB1 heat shock 27kDa protein 1 -0.0177786
IREB2 iron-responsive element binding protein 2 -0.0177568
UBAC1 UBA domain containing 1 -0.0177036
EML2 echinoderm microtubule associated protein like 2 -0.0176846
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.017674
UGP2 UDP-glucose pyrophosphorylase 2 -0.0176313
FBXL13 F-box and leucine-rich repeat protein 13 -0.017583
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -0.0174942
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0174816
TADA2A transcriptional adaptor 2A -0.0174451
MED15 mediator complex subunit 15 -0.0174324
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0174285
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -0.0173949
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.017366
AHCYL2 adenosylhomocysteinase-like 2 -0.017356
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -0.0173466
METTL15 methyltransferase like 15 -0.0172701
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 -0.0172639
CLIP2 CAP-GLY domain containing linker protein 2 -0.0172504
MTFR1 mitochondrial fission regulator 1 -0.0172399
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0172287
PLEC plectin -0.0172212
TBC1D20 TBC1 domain family, member 20 -0.0172039
ADIPOR2 adiponectin receptor 2 -0.0171724
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0171262
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0171128
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.0170921
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) -0.0170467
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0170144
ZBTB35 zinc finger and BTB domain containing 35 -0.0169869
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0169742
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0169537
RHBDD2 rhomboid domain containing 2 -0.0169296
SDC3 syndecan 3 -0.0169277
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0169182
AP2A1 adaptor-related protein complex 2, alpha 1 subunit -0.016902
NOSIP nitric oxide synthase interacting protein -0.0168826
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.0168636
NCOR2 nuclear receptor corepressor 2 -0.016849
C1ORF159 chromosome 1 open reading frame 159 -0.0168436
NCOR1 nuclear receptor corepressor 1 -0.016836
TBC1D32 TBC1 domain family, member 32 -0.0167749
TPD52L1 tumor protein D52-like 1 -0.0167747
RBSN rabenosyn, RAB effector -0.0167427
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -0.0167389
PDE4A phosphodiesterase 4A, cAMP-specific -0.0167266
ZMYND11 zinc finger, MYND-type containing 11 -0.0167204
KLHL24 kelch-like family member 24 -0.016706
SCAPER S-phase cyclin A-associated protein in the ER -0.0166774
TMEM59 transmembrane protein 59 -0.0166748
DGCR8 DGCR8 microprocessor complex subunit -0.0166733
SARS2 seryl-tRNA synthetase 2, mitochondrial -0.0166641
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -0.0166614
TOMM70 translocase of outer mitochondrial membrane 70 -0.0166301
BBX bobby sox homolog (Drosophila) -0.016615
ZHX3 zinc fingers and homeoboxes 3 -0.0165895
SLF2 SMC5-SMC6 complex localization factor 2 -0.0165747
SLC25A42 solute carrier family 25, member 42 -0.0165685
RSU1 Ras suppressor protein 1 -0.016558
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.0165562
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0165408
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.016539
C6ORF62 chromosome 6 open reading frame 62 -0.0165284
RHOBTB3 Rho-related BTB domain containing 3 -0.0164684
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0164666
NR2C2 nuclear receptor subfamily 2, group C, member 2 -0.0164639
TEX10 testis expressed 10 -0.0164163
ATAD5 ATPase family, AAA domain containing 5 -0.0164044
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0163783
TELO2 telomere maintenance 2 -0.0163654
AFDN afadin, adherens junction formation factor -0.016339
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0163142
IMMT inner membrane protein, mitochondrial -0.0162889
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0162677
TBC1D15 TBC1 domain family, member 15 -0.0162644
ECSIT ECSIT signalling integrator -0.0162331
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -0.0161322
FAM13A family with sequence similarity 13, member A -0.0161308
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0160961
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0160911
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0160862
INSIG1 insulin induced gene 1 -0.01607
GPR137 G protein-coupled receptor 137 -0.0160625
TRIM4 tripartite motif containing 4 -0.0160417
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0160264
UBE4B ubiquitination factor E4B -0.0160094
MBD4 methyl-CpG binding domain protein 4 -0.0159653
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.0159538
EIF4A3 eukaryotic translation initiation factor 4A3 -0.0159498
MOB3A MOB kinase activator 3A -0.0159408
ZNF292 zinc finger protein 292 -0.0159274
VCF1 VCP nuclear cofactor family member 1 -0.0159229
GOLGA2 golgin A2 -0.0159102
YY1 YY1 transcription factor -0.0158634
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -0.0158372
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0157996
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0157846
NOL4L nucleolar protein 4-like -0.0157558
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.0157514
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -0.0157483
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0157455
RHAG Rh-associated glycoprotein -0.0157441
VWDE von Willebrand factor D and EGF domains -0.0157357
CFDP1 craniofacial development protein 1 -0.0157056
PIP4P2 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 -0.0156957
ATAD3A ATPase family, AAA domain containing 3A -0.0156932
AGPS alkylglycerone phosphate synthase -0.0156879
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0156813
METAP1D methionyl aminopeptidase type 1D (mitochondrial) -0.0156783
TET3 tet methylcytosine dioxygenase 3 -0.015665
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -0.015665
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0156451
ADCY7 adenylate cyclase 7 -0.0156235
VEGFB vascular endothelial growth factor B -0.0156067
ODF2 outer dense fiber of sperm tails 2 -0.0155857
CDC123 cell division cycle 123 -0.0155431
CEP85L centrosomal protein 85kDa-like -0.0155395
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0155253
PRRC2A proline-rich coiled-coil 2A -0.0155155
TPM3 tropomyosin 3 -0.0155147
GRB2 growth factor receptor-bound protein 2 -0.0155112
PITPNA phosphatidylinositol transfer protein, alpha -0.015506
FERMT3 fermitin family member 3 -0.01548
CELF2 CUGBP, Elav-like family member 2 -0.0154683
E2F3 E2F transcription factor 3 -0.0154633
ANO6 anoctamin 6 -0.0154614
ZBTB43 zinc finger and BTB domain containing 43 -0.0154554
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.0154388
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0154092
FAT1 FAT atypical cadherin 1 -0.0153954
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -0.0153901
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0153894
ITSN2 intersectin 2 -0.015326
SNX4 sorting nexin 4 -0.0152947
ANKRD12 ankyrin repeat domain 12 -0.0152879
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.0152538
TPP2 tripeptidyl peptidase II -0.0152435
CHEK2 checkpoint kinase 2 -0.0152369
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0152204
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0152142
FNDC3A fibronectin type III domain containing 3A -0.0151977
SEPTIN11 septin 11 -0.0151793
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 -0.0150932
NCKAP1 NCK-associated protein 1 -0.0150767
TASP1 taspase, threonine aspartase, 1 -0.0150581
SMG7 SMG7 nonsense mediated mRNA decay factor -0.0150569
S100PBP S100P binding protein -0.0150432
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0150412
DTNBP1 dystrobrevin binding protein 1 -0.0150244
CACUL1 CDK2-associated, cullin domain 1 -0.0150172
CEP70 centrosomal protein 70kDa -0.0150096
CDK7 cyclin-dependent kinase 7 -0.0150093