K562_Obatoclax Mesylate_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Obatoclax Mesylate 1µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_Obatoclax Mesylate_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
MBNL1 muscleblind-like splicing regulator 1 0.132341
STXBP5 syntaxin binding protein 5 (tomosyn) 0.123273
PLCL1 phospholipase C-like 1 0.110104
MUSK muscle, skeletal, receptor tyrosine kinase 0.0772222
CPED1 cadherin-like and PC-esterase domain containing 1 0.0689441
EXOC4 exocyst complex component 4 0.0658957
PRKCB protein kinase C, beta 0.0644971
FNDC3B fibronectin type III domain containing 3B 0.0620106
ADGRV1 adhesion G protein-coupled receptor V1 0.0604483
ZEB2 zinc finger E-box binding homeobox 2 0.0547866
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0538583
RORA RAR-related orphan receptor A 0.0531719
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0523408
RTN4 reticulon 4 0.0513467
RHOBTB3 Rho-related BTB domain containing 3 0.051092
CNST consortin, connexin sorting protein 0.0499563
HBG1 hemoglobin, gamma A 0.0497342
TLN1 talin 1 0.0480553
RPS8 ribosomal protein S8 0.0473421
RPL37A ribosomal protein L37a 0.0459782
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.0459272
RPL13A ribosomal protein L13a 0.0454613
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.0446584
CALR calreticulin 0.04458
PRR14L proline rich 14-like 0.0445391
RPS2 ribosomal protein S2 0.0444647
BCL2L1 BCL2-like 1 0.0444072
HMGA1 high mobility group AT-hook 1 0.0439778
HLA-E major histocompatibility complex, class I, E 0.0427535
R3HDM1 R3H domain containing 1 0.0426028
ARID1A AT rich interactive domain 1A (SWI-like) 0.0425315
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0422321
CAPN1 calpain 1, (mu/I) large subunit 0.0415701
SH2B3 SH2B adaptor protein 3 0.0415084
CCDC91 coiled-coil domain containing 91 0.0405695
ABHD2 abhydrolase domain containing 2 0.0404339
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.0404338
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.0396944
RPL14 ribosomal protein L14 0.039515
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0391776
WDR70 WD repeat domain 70 0.0391601
ATM ATM serine/threonine kinase 0.0390464
STIM1 stromal interaction molecule 1 0.0383177
PHKB phosphorylase kinase, beta 0.0374914
HBG2 hemoglobin, gamma G 0.036775
RPLP2 ribosomal protein, large, P2 0.036771
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.036493
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0363107
LDLR low density lipoprotein receptor 0.0361597
FTL ferritin, light polypeptide 0.0351526
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0346055
CCNY cyclin Y 0.0344367
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0337905
RSRP1 arginine/serine-rich protein 1 0.0335055
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0334874
ANKRD17 ankyrin repeat domain 17 0.0334486
RPLP0 ribosomal protein, large, P0 0.0334308
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.033322
BIRC6 baculoviral IAP repeat containing 6 0.0332396
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0331367
CDK6 cyclin-dependent kinase 6 0.0327542
CHD1 chromodomain helicase DNA binding protein 1 0.0323462
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0323391
PRAME preferentially expressed antigen in melanoma 0.0323169
FAM13A family with sequence similarity 13, member A 0.0321965
EEA1 early endosome antigen 1 0.0319712
TBC1D5 TBC1 domain family, member 5 0.0319618
SMC6 structural maintenance of chromosomes 6 0.0318221
RBM28 RNA binding motif protein 28 0.0312817
EP300 E1A binding protein p300 0.0312158
EEF2 eukaryotic translation elongation factor 2 0.0311914
RAD21 RAD21 homolog (S. pombe) 0.0311505
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.0310205
CUL5 cullin 5 0.0309916
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0309913
NCAPD2 non-SMC condensin I complex, subunit D2 0.0309247
PTH2R parathyroid hormone 2 receptor 0.0308078
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0305631
AVL9 AVL9 homolog (S. cerevisiase) 0.0304804
CLCN3 chloride channel, voltage-sensitive 3 0.0301872
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0301526
ENOSF1 enolase superfamily member 1 0.0300622
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.0299552
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0299013
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0298664
TNRC6B trinucleotide repeat containing 6B 0.0298251
LIMS1 LIM and senescent cell antigen-like domains 1 0.0293887
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0293842
TOP2B topoisomerase (DNA) II beta 180kDa 0.0291906
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0289894
KIAA0586 KIAA0586 0.0286655
BCAS3 breast carcinoma amplified sequence 3 0.0286233
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.0285914
STAT5B signal transducer and activator of transcription 5B 0.0285351
ESRRB estrogen-related receptor beta 0.0284832
VWA8 von Willebrand factor A domain containing 8 0.0284492
TCERG1 transcription elongation regulator 1 0.0284048
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0284001
RPL7L1 ribosomal protein L7-like 1 0.0283895
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.0282512
CASS4 Cas scaffolding protein family member 4 0.0282262
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0281715
GLO1 glyoxalase I 0.027998
BTBD7 BTB (POZ) domain containing 7 0.0279164
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0277755
TJP1 tight junction protein 1 0.0277636
SLC10A7 solute carrier family 10, member 7 0.0277236
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.0276196
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0276194
LARP1 La ribonucleoprotein domain family, member 1 0.0275367
POM121 POM121 transmembrane nucleoporin 0.0274786
RTF2 replication termination factor 2 0.0274599
GSTO1 glutathione S-transferase omega 1 0.0273702
RCOR1 REST corepressor 1 0.027323
ARHGAP18 Rho GTPase activating protein 18 0.0271363
NUP62 nucleoporin 62kDa 0.0269955
MCAM melanoma cell adhesion molecule 0.0269448
CAB39 calcium binding protein 39 0.0269382
COX5B cytochrome c oxidase subunit Vb 0.0269262
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0269026
ELP4 elongator acetyltransferase complex subunit 4 0.0268831
ESYT1 extended synaptotagmin-like protein 1 0.0268827
DMD dystrophin 0.0268786
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0268043
OGA O-GlcNAcase 0.0264289
WDPCP WD repeat containing planar cell polarity effector 0.0263694
LNPEP leucyl/cystinyl aminopeptidase 0.0263532
TAPBP TAP binding protein (tapasin) 0.0263454
CDK19 cyclin-dependent kinase 19 0.026301
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.0261466
FYB1 FYN binding protein 1 0.0259617
GLS2 glutaminase 2 (liver, mitochondrial) 0.0259456
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0259202
DENND4A DENN/MADD domain containing 4A 0.0257922
PDLIM5 PDZ and LIM domain 5 0.0257341
MTFR1 mitochondrial fission regulator 1 0.025704
RRBP1 ribosome binding protein 1 0.0256897
KDM4C lysine (K)-specific demethylase 4C 0.0256799
RPS23 ribosomal protein S23 0.0256577
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.0255359
FNBP1 formin binding protein 1 0.0255034
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0254454
SCAND3 SCAN domain containing 3 0.0253761
RPS14 ribosomal protein S14 0.025375
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0253376
CAPRIN1 cell cycle associated protein 1 0.025317
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0253144
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0252223
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.0252042
SRGN serglycin 0.0251405
HOMER2 homer scaffolding protein 2 0.0250787
TMEM59 transmembrane protein 59 0.0250423
ACTN4 actinin, alpha 4 0.0249094
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.024896
CMC4 C-x(9)-C motif containing 4 0.0248661
ZNF367 zinc finger protein 367 0.0247885
GSE1 Gse1 coiled-coil protein 0.0246431
LASP1 LIM and SH3 protein 1 0.0244865
RRM1 ribonucleotide reductase M1 0.024163
TPR translocated promoter region, nuclear basket protein 0.0241276
RSF1 remodeling and spacing factor 1 0.0241185
GMPR guanosine monophosphate reductase 0.0241169
MBNL2 muscleblind-like splicing regulator 2 0.0240739
DOCK8 dedicator of cytokinesis 8 0.0240723
TGFB1 transforming growth factor, beta 1 0.0240402
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0240247
PHIP pleckstrin homology domain interacting protein 0.0239766
GOLIM4 golgi integral membrane protein 4 0.0239461
PKP4 plakophilin 4 0.0237954
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0237689
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.0237254
SMIM7 small integral membrane protein 7 0.0237208
USP3 ubiquitin specific peptidase 3 0.0237096
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0236972
SEC62 SEC62 homolog (S. cerevisiae) 0.0236959
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0236869
ZBTB20 zinc finger and BTB domain containing 20 0.0236841
ABI1 abl-interactor 1 0.0236642
HMBOX1 homeobox containing 1 0.0236485
RPS6 ribosomal protein S6 0.0236463
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.0236044
BRD4 bromodomain containing 4 0.0235196
RAB27A RAB27A, member RAS oncogene family 0.0234944
BLVRB biliverdin reductase B 0.0234919
PCM1 pericentriolar material 1 0.0234779
SMYD3 SET and MYND domain containing 3 0.0234753
FTH1 ferritin, heavy polypeptide 1 0.0234527
VWDE von Willebrand factor D and EGF domains 0.0233519
XKR3 XK, Kell blood group complex subunit-related family, member 3 0.0233493
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.0233144
XRRA1 X-ray radiation resistance associated 1 0.0232718
NPEPPS aminopeptidase puromycin sensitive 0.0231598
RPS24 ribosomal protein S24 0.0231045
SFXN1 sideroflexin 1 0.023082
HPCAL1 hippocalcin-like 1 0.0230745
THOC2 THO complex 2 0.0230249
VIM vimentin 0.0230087
ASPH aspartate beta-hydroxylase 0.0230079
CALU calumenin 0.0229853
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.0229457
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.022878
ATP5F1B ATP synthase F1 subunit beta 0.022832
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0228224
RPL32 ribosomal protein L32 0.0228137
CTTN cortactin 0.022808
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 0.0228043
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.0227688
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.022764
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0227414
STK4 serine/threonine kinase 4 0.022676
MIDEAS mitotic deacetylase associated SANT domain protein 0.0226414
BICD1 bicaudal D homolog 1 (Drosophila) 0.022525
CLIC1 chloride intracellular channel 1 0.022437
DCAKD dephospho-CoA kinase domain containing 0.0224161
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0223532
RINT1 RAD50 interactor 1 0.0222872
ATP5MC2 ATP synthase membrane subunit c locus 2 0.0220957
LEPROT leptin receptor overlapping transcript 0.0220905
TAOK3 TAO kinase 3 0.0220586
RPL15 ribosomal protein L15 0.0219981
SYCP2L synaptonemal complex protein 2-like 0.0218942
VTA1 vesicle (multivesicular body) trafficking 1 0.0218702
MDM4 MDM4, p53 regulator 0.0218032
XPO6 exportin 6 0.0217971
ADGRB3 adhesion G protein-coupled receptor B3 0.0217834
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.0217367
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.0217262
BABAM2 BRISC and BRCA1 A complex member 2 0.0217032
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0216444
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.0216249
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0216058
GATAD2B GATA zinc finger domain containing 2B 0.0215535
GRB10 growth factor receptor-bound protein 10 0.0214719
SNAP29 synaptosomal-associated protein, 29kDa 0.0214377
ARL8B ADP-ribosylation factor-like 8B 0.0214262
MARF1 meiosis regulator and mRNA stability factor 1 0.021418
ADGRL1 adhesion G protein-coupled receptor L1 0.0214126
GDI2 GDP dissociation inhibitor 2 0.0213355
ATP11B ATPase, class VI, type 11B 0.0212534
ZFP64 ZFP64 zinc finger protein 0.0212287
SLC38A10 solute carrier family 38, member 10 0.0212068
UBC ubiquitin C 0.0212046
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.0211968
GAB2 GRB2-associated binding protein 2 0.0211313
SAE1 SUMO1 activating enzyme subunit 1 0.0211229
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.021053
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0210478
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0209795
FBXW11 F-box and WD repeat domain containing 11 0.0208536
PDS5B PDS5 cohesin associated factor B 0.020797
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0207953
DOK7 docking protein 7 0.0207866
NALF1 NALCN channel auxiliary factor 1 0.0207664
MBTD1 mbt domain containing 1 0.0207463
CCAR1 cell division cycle and apoptosis regulator 1 0.0205895
MCU mitochondrial calcium uniporter 0.0205629
SERINC1 serine incorporator 1 0.0205546
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.0205443
ARHGAP6 Rho GTPase activating protein 6 0.0205317
DAPK1 death-associated protein kinase 1 0.0204115
DNAAF9 dynein axonemal assembly factor 9 0.0204043
XRN1 5'-3' exoribonuclease 1 0.0204041
TMEM33 transmembrane protein 33 0.0203846
SLC38A2 solute carrier family 38, member 2 0.0203844
RAB10 RAB10, member RAS oncogene family 0.0203841
MAST4 microtubule associated serine/threonine kinase family member 4 0.0203615
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0203451
CKAP5 cytoskeleton associated protein 5 0.020267
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0202219
ETNK1 ethanolamine kinase 1 0.0201916
SAMD4A sterile alpha motif domain containing 4A 0.0201883
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0201238
YIPF4 Yip1 domain family, member 4 0.0200859
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.0200738
GRB2 growth factor receptor-bound protein 2 0.0199531
RPL28 ribosomal protein L28 0.0199259
SETDB1 SET domain, bifurcated 1 0.0198607
SPIRE1 spire-type actin nucleation factor 1 0.0198376
C6ORF89 chromosome 6 open reading frame 89 0.0198203
MECP2 methyl CpG binding protein 2 0.0198192
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.0198033
PKN1 protein kinase N1 0.0197202
POTEF POTE ankyrin domain family, member F 0.0196987
CATSPERB catsper channel auxiliary subunit beta 0.0196937
PAK1IP1 PAK1 interacting protein 1 0.0196814
CSPP1 centrosome and spindle pole associated protein 1 0.0196545
GATD1 glutamine amidotransferase class 1 domain containing 1 0.019641
RGS20 regulator of G-protein signaling 20 0.0196099
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0196012
NGLY1 N-glycanase 1 0.0195976
CEP63 centrosomal protein 63kDa 0.0195044
ATP5MC3 ATP synthase membrane subunit c locus 3 0.0194712
SRBD1 S1 RNA binding domain 1 0.0194483
UBE2H ubiquitin-conjugating enzyme E2H 0.0194107
CLTCL1 clathrin, heavy chain-like 1 0.0193573
BTNL9 butyrophilin-like 9 0.0193501
RPS21 ribosomal protein S21 0.0193277
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.0193133
SPPL2A signal peptide peptidase like 2A 0.0191663
ANKRD12 ankyrin repeat domain 12 0.0191503
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0191493
ANKRD26 ankyrin repeat domain 26 0.0191378
RAD51B RAD51 paralog B 0.019111
INTS4 integrator complex subunit 4 0.0190294
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0190189
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0190094
SQLE squalene epoxidase 0.0189708
THADA thyroid adenoma associated 0.0189403
STAU2 staufen double-stranded RNA binding protein 2 0.0188902
RAB22A RAB22A, member RAS oncogene family 0.0188677
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0188609
TLE5 TLE family member 5, transcriptional modulator 0.0188448
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.0188055
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.0187786
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.0187257
H1-2 H1.2 linker histone, cluster member 0.0186981
TMEM260 transmembrane protein 260 0.0186897
EGFL7 EGF-like-domain, multiple 7 0.0186832
TBC1D4 TBC1 domain family, member 4 0.018668
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0186582
SEC24A SEC24 family member A 0.0186351
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0186335
TUBA1B tubulin, alpha 1b 0.0186012
IPO5 importin 5 0.0185878
RARS1 arginyl-tRNA synthetase 1 0.0185582
SFTPA2 surfactant protein A2 0.0185395
EDF1 endothelial differentiation-related factor 1 0.0185245
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.0185042
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0184941
ZZZ3 zinc finger, ZZ-type containing 3 0.0184925
CBX1 chromobox homolog 1 0.0184807
QPRT quinolinate phosphoribosyltransferase 0.0184712
MYO16 myosin XVI 0.0184654
RANGAP1 Ran GTPase activating protein 1 0.0184489
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0184311
SQSTM1 sequestosome 1 0.0184302
SLTM SAFB-like, transcription modulator 0.0183913
SMC4 structural maintenance of chromosomes 4 0.0183627
SUFU suppressor of fused homolog (Drosophila) 0.018362
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0183528
SKA2 spindle and kinetochore associated complex subunit 2 0.01835
EIF3D eukaryotic translation initiation factor 3, subunit D 0.0183274
FANCA Fanconi anemia, complementation group A 0.0183149
RPRD1B regulation of nuclear pre-mRNA domain containing 1B 0.018296
IRAK2 interleukin-1 receptor-associated kinase 2 0.0182691
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.0182197
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.0182152
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.0181461
IER3 immediate early response 3 0.0181199
PTGES2 prostaglandin E synthase 2 0.0180923
CRTAC1 cartilage acidic protein 1 0.0180885
LMAN2 lectin, mannose-binding 2 0.0180782
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0180643
KLHL24 kelch-like family member 24 0.0180514
FGGY FGGY carbohydrate kinase domain containing 0.0180501
MOGAT1 monoacylglycerol O-acyltransferase 1 0.0180492
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0180392
NAP1L1 nucleosome assembly protein 1-like 1 0.0180228
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.0180225
FNBP4 formin binding protein 4 0.0180061
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0179907
PRNP prion protein 0.0179897
SELENOI selenoprotein I 0.0179842
ZNF273 zinc finger protein 273 0.0179831
BBS4 Bardet-Biedl syndrome 4 0.0179299
KHDC4 KH domain containing 4, pre-mRNA splicing factor 0.0178732
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.017871
SETX senataxin 0.0178638
CNTN5 contactin 5 0.0178176
THSD4 thrombospondin, type I, domain containing 4 0.0178147
PDIA3 protein disulfide isomerase family A, member 3 0.0178128
ASXL2 additional sex combs like transcriptional regulator 2 0.0177436
RPL18 ribosomal protein L18 0.0177416
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.017713
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0177013
POLK polymerase (DNA directed) kappa 0.017685
NVL nuclear VCP-like 0.0176764
ANTXR2 anthrax toxin receptor 2 0.0176743
CREB5 cAMP responsive element binding protein 5 0.0176085
GPC5 glypican 5 0.0175741
MYO18B myosin XVIIIB 0.0175576
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.0175523
MECR mitochondrial trans-2-enoyl-CoA reductase 0.0175484
YIPF5 Yip1 domain family, member 5 0.017515
MYEOV myeloma overexpressed 0.0175144
LCLAT1 lysocardiolipin acyltransferase 1 0.0174982
DNM2 dynamin 2 0.0174704
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0174502
HBE1 hemoglobin, epsilon 1 0.0174482
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0174249
AFDN afadin, adherens junction formation factor 0.0173574
CCDC124 coiled-coil domain containing 124 0.0173466
ZNF175 zinc finger protein 175 0.0173407
PHF3 PHD finger protein 3 0.01733
LONP1 lon peptidase 1, mitochondrial 0.0173042
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.017301
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0172955
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0172845
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.0172833
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0172694
THAP12 THAP domain containing 12 0.0172572
KIAA1958 KIAA1958 0.0172105
ELAVL1 ELAV like RNA binding protein 1 0.01719
TTC7B tetratricopeptide repeat domain 7B 0.0171648
ACD adrenocortical dysplasia homolog (mouse) 0.0171577
RACK1 receptor for activated C kinase 1 0.0171263
FAM136A family with sequence similarity 136, member A 0.0171246
LETMD1 LETM1 domain containing 1 0.0170865
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.0170098
BRWD3 bromodomain and WD repeat domain containing 3 0.0169999
CREB3L1 cAMP responsive element binding protein 3-like 1 0.0169665
TMCO1 transmembrane and coiled-coil domains 1 0.0169472
H2AZ1 H2A.Z variant histone 1 0.0169467
MACF1 microtubule-actin crosslinking factor 1 0.016933
DTNBP1 dystrobrevin binding protein 1 0.0169292
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.0169292
SEC24D SEC24 family member D 0.0169214
PTK2B protein tyrosine kinase 2 beta 0.0169179
ZNF41 zinc finger protein 41 0.0168956
ACTG1 actin gamma 1 0.0168772
CACUL1 CDK2-associated, cullin domain 1 0.016871
GOLGA4 golgin A4 0.0168695
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0168521
NCAPG non-SMC condensin I complex, subunit G 0.0168489
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0168218
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 0.0168084
SCAF8 SR-related CTD-associated factor 8 0.0167882
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.0167847
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0167745
TMEM164 transmembrane protein 164 0.0167526
CLEC16A C-type lectin domain family 16, member A 0.016725
DIAPH3 diaphanous-related formin 3 0.0166935
PTPRA protein tyrosine phosphatase, receptor type, A 0.0166897
PTPN7 protein tyrosine phosphatase, non-receptor type 7 0.0166362
STRIP2 striatin interacting protein 2 0.0166354
MED4 mediator complex subunit 4 0.0166334
CAVIN2 caveolae associated protein 2 0.0166057
ANKRD36C ankyrin repeat domain 36C 0.0165919
EIF5B eukaryotic translation initiation factor 5B 0.0165846
UBB ubiquitin B 0.0165829
ENSA endosulfine alpha 0.0165302
SNX29 sorting nexin 29 0.0165189
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0165189
TMEM131 transmembrane protein 131 0.0165003
FGF13 fibroblast growth factor 13 0.0164825
CD47 CD47 molecule 0.0164728
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0164507
XBP1 X-box binding protein 1 0.0164442
GAN gigaxonin 0.0163989
MCM7 minichromosome maintenance complex component 7 0.0163968
PLA2G12A phospholipase A2, group XIIA 0.0163765
SRSF11 serine/arginine-rich splicing factor 11 0.0163495
ACSL1 acyl-CoA synthetase long-chain family member 1 0.0163319
TMEM68 transmembrane protein 68 0.0162996
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0162977
PGPEP1 pyroglutamyl-peptidase I 0.016276
RPS5 ribosomal protein S5 0.0162436
CUL4A cullin 4A 0.0162389
INTS9 integrator complex subunit 9 0.0162255
MARK2 MAP/microtubule affinity-regulating kinase 2 0.0161838
CTSD cathepsin D 0.0161831
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.0161463
MXD1 MAX dimerization protein 1 0.0161205
ALG3 ALG3, alpha-1,3- mannosyltransferase 0.0161152
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 0.0161114
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.0161095
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.016101
C3ORF62 chromosome 3 open reading frame 62 0.0160589
RPS17 ribosomal protein S17 0.0160291
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.0159914
COG8 component of oligomeric golgi complex 8 0.015977
TAGLN2 transgelin 2 0.0159756
CDC14A cell division cycle 14A 0.0159596
TPX2 TPX2, microtubule-associated 0.0158977
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0158778
EPS15 epidermal growth factor receptor pathway substrate 15 0.0158685
RPL4 ribosomal protein L4 0.0158682
TUSC3 tumor suppressor candidate 3 0.0158126
ACVR2B activin A receptor, type IIB 0.0157692
OAZ1 ornithine decarboxylase antizyme 1 0.0157578
COPA coatomer protein complex, subunit alpha 0.0157502
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.0157334
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.015704
LMBR1L limb development membrane protein 1-like 0.0156767
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0156623
TSC22D4 TSC22 domain family, member 4 0.0156519
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.0156335
STYXL1 serine/threonine/tyrosine interacting-like 1 0.0156177
SIK2 salt-inducible kinase 2 0.0155909
LPIN2 lipin 2 0.0155759
ACOT9 acyl-CoA thioesterase 9 0.0155568
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 0.0155508
INTS2 integrator complex subunit 2 0.015541
NEMF nuclear export mediator factor 0.0155124
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.0154989
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.015477
BAG1 BCL2-associated athanogene 0.0154714
ZNF43 zinc finger protein 43 0.0154355
OSBPL5 oxysterol binding protein-like 5 0.0154173
DNA2 DNA replication helicase/nuclease 2 0.0154117

decreased expression

Symbol Name Standardized Value
FAF1 Fas (TNFRSF6) associated factor 1 -0.0728463
USP32 ubiquitin specific peptidase 32 -0.07056
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0693583
MAML2 mastermind-like 2 (Drosophila) -0.0666931
ARL15 ADP-ribosylation factor-like 15 -0.0655266
EPB41 erythrocyte membrane protein band 4.1 -0.0654479
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0649337
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0600752
PTK2 protein tyrosine kinase 2 -0.05934
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0550873
UBE3C ubiquitin protein ligase E3C -0.053219
KMT2C lysine (K)-specific methyltransferase 2C -0.0513113
FDPS farnesyl diphosphate synthase -0.0505823
RELN reelin -0.0503881
SCFD2 sec1 family domain containing 2 -0.0496597
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0487892
ANKRD11 ankyrin repeat domain 11 -0.0484074
RBM15 RNA binding motif protein 15 -0.046963
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0464882
KRT8 keratin 8, type II -0.0463924
LARP1B La ribonucleoprotein domain family, member 1B -0.0462778
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0458313
JARID2 jumonji, AT rich interactive domain 2 -0.0458037
PHACTR4 phosphatase and actin regulator 4 -0.0453763
TUBB tubulin, beta class I -0.045154
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0447913
CEP350 centrosomal protein 350kDa -0.0442199
TASOR2 transcription activation suppressor family member 2 -0.0440936
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0437733
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.0434788
TAOK1 TAO kinase 1 -0.0431761
PRRC2C proline-rich coiled-coil 2C -0.0429078
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0424423
CALN1 calneuron 1 -0.0424001
SOX6 SRY (sex determining region Y)-box 6 -0.041405
STK24 serine/threonine kinase 24 -0.0409905
SETD5 SET domain containing 5 -0.040775
NMU neuromedin U -0.0404188
SSBP2 single-stranded DNA binding protein 2 -0.0402181
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -0.0399777
CENPP centromere protein P -0.0399279
CENPF centromere protein F, 350/400kDa -0.0386663
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0383898
DENND1A DENN/MADD domain containing 1A -0.0382592
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0378294
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0372734
CTBP2 C-terminal binding protein 2 -0.0371627
USP48 ubiquitin specific peptidase 48 -0.0371208
RNF217 ring finger protein 217 -0.0369156
USP15 ubiquitin specific peptidase 15 -0.0369018
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.0367678
TNRC18 trinucleotide repeat containing 18 -0.0359934
IPO7 importin 7 -0.0359539
TET3 tet methylcytosine dioxygenase 3 -0.0359479
FN1 fibronectin 1 -0.0355286
AGO3 argonaute RISC catalytic component 3 -0.0354038
MYO1D myosin ID -0.0348693
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0344117
TFCP2 transcription factor CP2 -0.0342545
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0340294
PLD3 phospholipase D family, member 3 -0.0337735
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0335172
PKN2 protein kinase N2 -0.0335148
DOCK9 dedicator of cytokinesis 9 -0.033041
CLTC clathrin, heavy chain (Hc) -0.0329046
MKI67 marker of proliferation Ki-67 -0.0328529
AHNAK AHNAK nucleoprotein -0.0328498
LYRM4 LYR motif containing 4 -0.0327016
KIF14 kinesin family member 14 -0.0320638
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0315517
NSD1 nuclear receptor binding SET domain protein 1 -0.0314463
WRN Werner syndrome, RecQ helicase-like -0.0313103
CHD8 chromodomain helicase DNA binding protein 8 -0.03129
IPO9 importin 9 -0.0312634
SSH2 slingshot protein phosphatase 2 -0.0310975
CD2AP CD2-associated protein -0.0307749
EML4 echinoderm microtubule associated protein like 4 -0.0306825
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0305995
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0305733
TMCC1 transmembrane and coiled-coil domain family 1 -0.0305343
UBAP2 ubiquitin associated protein 2 -0.0305215
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0304432
STAU1 staufen double-stranded RNA binding protein 1 -0.0303316
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.0302099
RSRC1 arginine/serine-rich coiled-coil 1 -0.0300162
SLC39A11 solute carrier family 39, member 11 -0.0299363
ANK1 ankyrin 1, erythrocytic -0.0297693
FRRS1 ferric-chelate reductase 1 -0.0297569
AFF1 AF4/FMR2 family, member 1 -0.0292042
NMT1 N-myristoyltransferase 1 -0.0288115
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0287593
TRIM44 tripartite motif containing 44 -0.0287469
MSI2 musashi RNA-binding protein 2 -0.0286127
LRP12 low density lipoprotein receptor-related protein 12 -0.0285425
TNPO2 transportin 2 -0.0284954
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0284873
CUX1 cut-like homeobox 1 -0.0284758
ZFPM2 zinc finger protein, FOG family member 2 -0.0283758
AGPS alkylglycerone phosphate synthase -0.0283483
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.028336
ELOVL6 ELOVL fatty acid elongase 6 -0.0283086
FLNA filamin A, alpha -0.0283003
MED12 mediator complex subunit 12 -0.0282953
KMT2E lysine (K)-specific methyltransferase 2E -0.0280889
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0280869
TMPO thymopoietin -0.02807
FAM222B family with sequence similarity 222, member B -0.0280495
AHI1 Abelson helper integration site 1 -0.0279925
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.027878
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.027804
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0275842
SRPK2 SRSF protein kinase 2 -0.0275342
STAG2 stromal antigen 2 -0.027515
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0274639
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0274268
CLIP1 CAP-GLY domain containing linker protein 1 -0.0273981
AGFG1 ArfGAP with FG repeats 1 -0.0272793
TXNRD1 thioredoxin reductase 1 -0.0272012
ZNF804A zinc finger protein 804A -0.0271346
SRRM2 serine/arginine repetitive matrix 2 -0.0269709
COMT catechol-O-methyltransferase -0.0269428
ZFC3H1 zinc finger, C3H1-type containing -0.0267981
PICALM phosphatidylinositol binding clathrin assembly protein -0.0267079
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -0.0266062
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0265667
SETD2 SET domain containing 2 -0.0264771
MAP2K1 mitogen-activated protein kinase kinase 1 -0.0262995
PITPNA phosphatidylinositol transfer protein, alpha -0.0260789
NCOA3 nuclear receptor coactivator 3 -0.0258169
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0257996
FAM171A1 family with sequence similarity 171, member A1 -0.0257266
KRIT1 KRIT1, ankyrin repeat containing -0.0253988
NSD2 nuclear receptor binding SET domain protein 2 -0.0250608
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0250575
FLOT2 flotillin 2 -0.0250263
CDC27 cell division cycle 27 -0.0249555
NF1 neurofibromin 1 -0.0248145
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0247939
KCTD20 potassium channel tetramerization domain containing 20 -0.0247755
CLASP1 cytoplasmic linker associated protein 1 -0.0246659
WASF2 WAS protein family, member 2 -0.0246203
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.0245183
KIF2C kinesin family member 2C -0.0244139
MYH9 myosin, heavy chain 9, non-muscle -0.0242836
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -0.0241452
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0240876
UBE3D ubiquitin protein ligase E3D -0.024035
FAM117A family with sequence similarity 117, member A -0.0240148
WDR26 WD repeat domain 26 -0.024009
RPS19 ribosomal protein S19 -0.0239164
PUS7 pseudouridylate synthase 7 (putative) -0.0239049
ADGRE2 adhesion G protein-coupled receptor E2 -0.0238976
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -0.0238784
LBR lamin B receptor -0.0238131
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0237636
ZNF644 zinc finger protein 644 -0.0236616
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0235853
SMC1A structural maintenance of chromosomes 1A -0.023557
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 -0.0235056
POM121C POM121 transmembrane nucleoporin C -0.0234532
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0234202
RBBP8 retinoblastoma binding protein 8 -0.023307
TRIM24 tripartite motif containing 24 -0.0233042
FOXK2 forkhead box K2 -0.0232876
AMBRA1 autophagy/beclin-1 regulator 1 -0.0232305
COG5 component of oligomeric golgi complex 5 -0.0231489
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0231066
H2BC8 H2B clustered histone 8 -0.0230976
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0230943
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0229421
BZW2 basic leucine zipper and W2 domains 2 -0.0228504
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0228352
CDK13 cyclin-dependent kinase 13 -0.0227886
KIF20B kinesin family member 20B -0.0227038
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0227007
DCHS2 dachsous cadherin-related 2 -0.0226827
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0226663
SRRM1 serine/arginine repetitive matrix 1 -0.0225723
VMP1 vacuole membrane protein 1 -0.0225384
EIF3J eukaryotic translation initiation factor 3, subunit J -0.0225346
KRT19 keratin 19, type I -0.0224846
GLUL glutamate-ammonia ligase -0.0224401
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0224329
SMC3 structural maintenance of chromosomes 3 -0.0224204
HDAC1 histone deacetylase 1 -0.022292
MPHOSPH9 M-phase phosphoprotein 9 -0.0222272
SCAI suppressor of cancer cell invasion -0.0222057
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.02217
CFH complement factor H -0.0221595
SPRED1 sprouty-related, EVH1 domain containing 1 -0.0221495
RAP1B RAP1B, member of RAS oncogene family -0.022124
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.0220805
YY1AP1 YY1 associated protein 1 -0.0220552
RBBP4 retinoblastoma binding protein 4 -0.021939
ANO10 anoctamin 10 -0.0218207
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0217965
ENO1 enolase 1, (alpha) -0.0217893
FAR1 fatty acyl CoA reductase 1 -0.021705
CCSER2 coiled-coil serine-rich protein 2 -0.0215375
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0215135
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0214576
NUP214 nucleoporin 214kDa -0.0213737
MICU1 mitochondrial calcium uptake 1 -0.0213702
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0213654
KNL1 kinetochore scaffold 1 -0.0213162
AKAP11 A kinase (PRKA) anchor protein 11 -0.0212663
ADD3 adducin 3 (gamma) -0.0212639
SCAF4 SR-related CTD-associated factor 4 -0.0212328
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.0211805
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.0211803
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -0.0211243
TRIM27 tripartite motif containing 27 -0.0211134
PCDH9 protocadherin 9 -0.0210708
MSH2 mutS homolog 2 -0.0210212
SPPL3 signal peptide peptidase like 3 -0.0209242
ZNF83 zinc finger protein 83 -0.0209087
NFYC nuclear transcription factor Y, gamma -0.020894
OSBPL9 oxysterol binding protein-like 9 -0.020854
DCAF10 DDB1 and CUL4 associated factor 10 -0.020833
PLBD2 phospholipase B domain containing 2 -0.020789
COMMD10 COMM domain containing 10 -0.0207791
IFT88 intraflagellar transport 88 -0.0207784
MYLIP myosin regulatory light chain interacting protein -0.0206831
PDE8A phosphodiesterase 8A -0.020637
AGO1 argonaute RISC catalytic component 1 -0.0205932
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0205565
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0204192
UBE3A ubiquitin protein ligase E3A -0.0204114
MDN1 MDN1, midasin homolog (yeast) -0.0203946
SUMF1 sulfatase modifying factor 1 -0.0203817
ANLN anillin, actin binding protein -0.0203673
DSTYK dual serine/threonine and tyrosine protein kinase -0.020309
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0202735
SLC22A23 solute carrier family 22, member 23 -0.0202488
SGO1 shugoshin 1 -0.0202181
AK1 adenylate kinase 1 -0.0202032
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0201354
PNPLA8 patatin-like phospholipase domain containing 8 -0.0200896
RPLP1 ribosomal protein, large, P1 -0.020072
TUT7 terminal uridylyl transferase 7 -0.0200557
SOX5 SRY (sex determining region Y)-box 5 -0.0200365
NRF1 nuclear respiratory factor 1 -0.0199668
LRRC41 leucine rich repeat containing 41 -0.01992
GSTP1 glutathione S-transferase pi 1 -0.0199
MED13L mediator complex subunit 13-like -0.0198986
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.019885
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0198584
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0198452
SLC35F5 solute carrier family 35, member F5 -0.0198431
C1ORF159 chromosome 1 open reading frame 159 -0.0198416
NPAT nuclear protein, ataxia-telangiectasia locus -0.0198116
ZNF124 zinc finger protein 124 -0.0197853
SLC30A7 solute carrier family 30 (zinc transporter), member 7 -0.0197833
TANGO6 transport and golgi organization 6 homolog (Drosophila) -0.0197381
MON2 MON2 homolog (S. cerevisiae) -0.0197299
PRPF6 pre-mRNA processing factor 6 -0.019654
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.019636
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.0196189
UBE4B ubiquitination factor E4B -0.0195784
PHF20 PHD finger protein 20 -0.0195483
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0195474
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0195379
BPTF bromodomain PHD finger transcription factor -0.019535
GPHN gephyrin -0.0194881
TMEM245 transmembrane protein 245 -0.0194294
CUL3 cullin 3 -0.0193925
ATXN2 ataxin 2 -0.0193236
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0193057
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0193047
BBX bobby sox homolog (Drosophila) -0.019277
CDC123 cell division cycle 123 -0.0192543
ZNF430 zinc finger protein 430 -0.0192303
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0192218
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0191558
ARMH3 armadillo like helical domain containing 3 -0.0190631
UBE2N ubiquitin-conjugating enzyme E2N -0.0189949
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0189885
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0188825
DOCK11 dedicator of cytokinesis 11 -0.0188703
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0188324
METAP1 methionyl aminopeptidase 1 -0.018813
RANBP9 RAN binding protein 9 -0.0188018
KEL Kell blood group, metallo-endopeptidase -0.018754
ECE1 endothelin converting enzyme 1 -0.0186541
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0186535
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0186134
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0186
SFXN5 sideroflexin 5 -0.0185928
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -0.0185556
RNF157 ring finger protein 157 -0.0185534
MTDH metadherin -0.0185212
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -0.0184579
VCL vinculin -0.0184573
RPL23A ribosomal protein L23a -0.0184217
PRKX protein kinase, X-linked -0.0183432
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.0183335
USP8 ubiquitin specific peptidase 8 -0.0183331
NOL9 nucleolar protein 9 -0.0183199
H2AZ2 H2A.Z variant histone 2 -0.0183139
ANXA1 annexin A1 -0.018289
UBP1 upstream binding protein 1 (LBP-1a) -0.0182792
MFSD11 major facilitator superfamily domain containing 11 -0.0182378
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0182357
SMAD3 SMAD family member 3 -0.0182107
MORF4L2 mortality factor 4 like 2 -0.0182094
APTX aprataxin -0.0181537
EXT1 exostosin glycosyltransferase 1 -0.0180849
RPL8 ribosomal protein L8 -0.0180761
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0180707
BRI3BP BRI3 binding protein -0.0180618
CCDC88A coiled-coil domain containing 88A -0.0180082
SNRK SNF related kinase -0.0180048
ACLY ATP citrate lyase -0.0179523
RBBP6 retinoblastoma binding protein 6 -0.017949
RHOA ras homolog family member A -0.0179384
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0179351
UTP4 UTP4 small subunit processome component -0.0179306
RNF216 ring finger protein 216 -0.0178865
TGFBR1 transforming growth factor, beta receptor 1 -0.0178864
BMP2K BMP2 inducible kinase -0.0178477
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -0.0178139
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.017801
PAXBP1 PAX3 and PAX7 binding protein 1 -0.0177955
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0177946
IKZF4 IKAROS family zinc finger 4 (Eos) -0.0177492
TSLIG1 tRNA splicing ligase complex subunit 1 -0.0177305
LMBR1 limb development membrane protein 1 -0.017704
ZCCHC17 zinc finger, CCHC domain containing 17 -0.0176692
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0176504
SREBF1 sterol regulatory element binding transcription factor 1 -0.0176224
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0175983
HIPK2 homeodomain interacting protein kinase 2 -0.0175905
SYMPK symplekin -0.0175726
CDC16 cell division cycle 16 -0.017509
IREB2 iron-responsive element binding protein 2 -0.017505
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0174991
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0174976
ORAI2 ORAI calcium release-activated calcium modulator 2 -0.017488
MEIOB meiosis specific with OB domains -0.0174867
CEP85 centrosomal protein 85kDa -0.0174577
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -0.0174171
TANK TRAF family member-associated NFKB activator -0.0173078
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.0172383
MAST2 microtubule associated serine/threonine kinase 2 -0.0172284
MYO3B myosin IIIB -0.0171826
NIPBL Nipped-B homolog (Drosophila) -0.0171123
SMG7 SMG7 nonsense mediated mRNA decay factor -0.0170872
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0170457
SS18 synovial sarcoma translocation, chromosome 18 -0.0170356
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -0.0169794
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0169542
NBAS neuroblastoma amplified sequence -0.0169408
MDC1 mediator of DNA-damage checkpoint 1 -0.0169273
ATAD5 ATPase family, AAA domain containing 5 -0.0169264
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0168828
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0168736
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0168189
TMEM131L transmembrane 131 like -0.0168033
PCNT pericentrin -0.0167786
SINHCAF SIN3-HDAC complex associated factor -0.0167738
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -0.0167537
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0167418
LDHA lactate dehydrogenase A -0.0166641
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0165849
LIN9 lin-9 DREAM MuvB core complex component -0.0165814
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0165546
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0165352
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.0165247
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0164776
KMT5B lysine methyltransferase 5B -0.0164732
NUP155 nucleoporin 155kDa -0.016463
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 -0.0164497
RNASE3 ribonuclease, RNase A family, 3 -0.0164411
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0164338
CDH12 cadherin 12, type 2 (N-cadherin 2) -0.016419
KRTAP11-1 keratin associated protein 11-1 -0.0163968
RUFY2 RUN and FYVE domain containing 2 -0.016359
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.0162861
DNPEP aspartyl aminopeptidase -0.0162717
PRKCSH protein kinase C substrate 80K-H -0.0162552
STIP1 stress-induced phosphoprotein 1 -0.0162485
RHAG Rh-associated glycoprotein -0.0162359
TEC tec protein tyrosine kinase -0.0162125
NUDCD1 NudC domain containing 1 -0.0162117
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.0161726
RHCE Rh blood group, CcEe antigens -0.0161606
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0161329
PRKCA protein kinase C, alpha -0.0161077
CLCN7 chloride channel, voltage-sensitive 7 -0.0160624
TIPRL TOR signaling pathway regulator -0.0160417
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0160352
DCTN2 dynactin 2 (p50) -0.0160351
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0160344
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.016025
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.0160034
NUP43 nucleoporin 43kDa -0.0160033
KIFC1 kinesin family member C1 -0.0159826
ITGAV integrin, alpha V -0.0159747
RASA2 RAS p21 protein activator 2 -0.0159488
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0159177
GYS1 glycogen synthase 1 (muscle) -0.0159088
DNAH14 dynein, axonemal, heavy chain 14 -0.0159042
RDX radixin -0.0158975
BMAL2 basic helix-loop-helix ARNT like 2 -0.0158945
CEP57 centrosomal protein 57kDa -0.0158381
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 -0.0158356
RNF24 ring finger protein 24 -0.0158238
HDAC2 histone deacetylase 2 -0.0158193
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.0157964
COX19 COX19 cytochrome c oxidase assembly factor -0.0157929
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0157404
PITX1 paired-like homeodomain 1 -0.0157364
RNF115 ring finger protein 115 -0.0157025
DGCR2 DiGeorge syndrome critical region gene 2 -0.015695
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.0156806
MED27 mediator complex subunit 27 -0.0156738
WNT5B wingless-type MMTV integration site family, member 5B -0.0156705
ARB2A ARB2 cotranscriptional regulator A -0.0156627
CUL1 cullin 1 -0.0156561
HAT1 histone acetyltransferase 1 -0.015444
NUDC nudC nuclear distribution protein -0.0154394
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0154362
OSBPL3 oxysterol binding protein-like 3 -0.0154284
COMMD1 copper metabolism (Murr1) domain containing 1 -0.0154099
ZNF148 zinc finger protein 148 -0.0153775
CDC25C cell division cycle 25C -0.0153304
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0152978
PKM pyruvate kinase, muscle -0.0152949
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.0152548
TYK2 tyrosine kinase 2 -0.015234
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0152271
CSMD1 CUB and Sushi multiple domains 1 -0.0152203
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0152193
MEPCE methylphosphate capping enzyme -0.0152124
TTC17 tetratricopeptide repeat domain 17 -0.0152085
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0152021
OXSR1 oxidative stress responsive 1 -0.0151996
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0151125
KAT6A K(lysine) acetyltransferase 6A -0.0151008
NHP2 NHP2 ribonucleoprotein -0.0150908
FAM193A family with sequence similarity 193, member A -0.0150869
TM9SF3 transmembrane 9 superfamily member 3 -0.015072
NUBP2 nucleotide binding protein 2 -0.0150715
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -0.0150708
WSB1 WD repeat and SOCS box containing 1 -0.0150687
RANBP3 RAN binding protein 3 -0.01501
PHGDH phosphoglycerate dehydrogenase -0.0149994
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -0.0149967
TRIM33 tripartite motif containing 33 -0.0149915
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.0149843
RBM26 RNA binding motif protein 26 -0.0149685
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0149629
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.0149183
MTG2 mitochondrial ribosome-associated GTPase 2 -0.014906
FANCI Fanconi anemia, complementation group I -0.0148864
GFOD2 glucose-fructose oxidoreductase domain containing 2 -0.0148812
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -0.014878
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0148745
STX5 syntaxin 5 -0.0148717
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -0.0148438
OSBP oxysterol binding protein -0.0148385
BST2 bone marrow stromal cell antigen 2 -0.0148313
SMC5 structural maintenance of chromosomes 5 -0.014815
FOXP1 forkhead box P1 -0.0148063
AFG3L2 AFG3-like AAA ATPase 2 -0.0147817
LYPLAL1 lysophospholipase-like 1 -0.0147679
LRRC69 leucine rich repeat containing 69 -0.0147647
CDK4 cyclin-dependent kinase 4 -0.014749
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.0147452
HELQ helicase, POLQ-like -0.0147366
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.0147238
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0147133
IFRD1 interferon-related developmental regulator 1 -0.0147052
PPME1 protein phosphatase methylesterase 1 -0.0147024
VGLL4 vestigial-like family member 4 -0.014695
CARS1 cysteinyl-tRNA synthetase 1 -0.0146634
CCSAP centriole, cilia and spindle-associated protein -0.0146615
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0146387
RRP1B ribosomal RNA processing 1B -0.0146188
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 -0.014614
KNTC1 kinetochore associated 1 -0.014611
RAB12 RAB12, member RAS oncogene family -0.0145776
LTN1 listerin E3 ubiquitin protein ligase 1 -0.0145743
GPR137 G protein-coupled receptor 137 -0.0145409
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0145242
ANO6 anoctamin 6 -0.0145125
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.0144852
LIMD1 LIM domains containing 1 -0.0144741
POLH polymerase (DNA directed), eta -0.0144661
SP3 Sp3 transcription factor -0.0144303
TRNAU1AP tRNA selenocysteine 1 associated protein 1 -0.0144292
SLC44A5 solute carrier family 44, member 5 -0.0144279
MEF2C myocyte enhancer factor 2C -0.0143826
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0143713
PPP1R8 protein phosphatase 1, regulatory subunit 8 -0.0143679
C11ORF58 chromosome 11 open reading frame 58 -0.0143667
SFPQ splicing factor proline/glutamine-rich -0.0143655
TLK1 tousled-like kinase 1 -0.0143621
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 -0.0143527
PLAGL1 pleiomorphic adenoma gene-like 1 -0.0143434