K562_SGI-1776 free base_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SGI-1776 free base 100nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
Similar Terms
Downloads & Tools

Genes

1000 genes differentially expressed following the K562_SGI-1776 free base_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PCDH9 protocadherin 9 0.142655
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0999077
ZFAND3 zinc finger, AN1-type domain 3 0.0835836
AIG1 androgen-induced 1 0.0774404
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0767114
FGF13 fibroblast growth factor 13 0.0715726
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0711425
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0694369
RABGAP1L RAB GTPase activating protein 1-like 0.0622535
ZNF609 zinc finger protein 609 0.0543609
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0531718
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0523026
RSRC1 arginine/serine-rich coiled-coil 1 0.0518481
GSE1 Gse1 coiled-coil protein 0.0510059
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0507221
NBAS neuroblastoma amplified sequence 0.0499698
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0497927
ZMYND8 zinc finger, MYND-type containing 8 0.04874
SIK3 SIK family kinase 3 0.0485888
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0478859
CNTNAP2 contactin associated protein-like 2 0.047203
MYO18B myosin XVIIIB 0.0470885
KIF2A kinesin heavy chain member 2A 0.0464321
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0459808
MYO1D myosin ID 0.0445435
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0444527
RUNX1 runt-related transcription factor 1 0.0443344
BCAS3 breast carcinoma amplified sequence 3 0.0430191
EHBP1 EH domain binding protein 1 0.042679
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0426743
STAU2 staufen double-stranded RNA binding protein 2 0.0423524
GLG1 golgi glycoprotein 1 0.0422809
PTGES2 prostaglandin E synthase 2 0.0419195
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.0411421
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0409092
FUBP1 far upstream element (FUSE) binding protein 1 0.0401098
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0399561
THRAP3 thyroid hormone receptor associated protein 3 0.0399039
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.0395135
TPR translocated promoter region, nuclear basket protein 0.0393914
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0393898
SNX9 sorting nexin 9 0.0393499
FANCD2 Fanconi anemia, complementation group D2 0.0390098
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0388336
STK24 serine/threonine kinase 24 0.0385665
RANBP9 RAN binding protein 9 0.0384795
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0384606
SUMF1 sulfatase modifying factor 1 0.0380382
DCAF7 DDB1 and CUL4 associated factor 7 0.0379417
VRK1 vaccinia related kinase 1 0.0378332
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0373843
AFF1 AF4/FMR2 family, member 1 0.0371672
FOXP1 forkhead box P1 0.0366665
CAMTA1 calmodulin binding transcription activator 1 0.036557
CTTN cortactin 0.0365149
HDAC8 histone deacetylase 8 0.0360911
PCM1 pericentriolar material 1 0.0354364
SCAF8 SR-related CTD-associated factor 8 0.0353877
SPATS2 spermatogenesis associated, serine-rich 2 0.0353249
GPC5 glypican 5 0.0351054
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0349999
RNASEH1 ribonuclease H1 0.0348706
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0347325
SASH1 SAM and SH3 domain containing 1 0.0346975
ZCCHC7 zinc finger, CCHC domain containing 7 0.0344312
RIPOR3 RIPOR family member 3 0.0342162
NIBAN1 niban apoptosis regulator 1 0.0342102
AATF apoptosis antagonizing transcription factor 0.0341845
TNIK TRAF2 and NCK interacting kinase 0.0340171
NCALD neurocalcin delta 0.0339904
ADGRV1 adhesion G protein-coupled receptor V1 0.0339011
ATG7 autophagy related 7 0.0338485
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0338224
CENPP centromere protein P 0.0338204
FANCI Fanconi anemia, complementation group I 0.0326365
PICALM phosphatidylinositol binding clathrin assembly protein 0.0321581
MAU2 MAU2 sister chromatid cohesion factor 0.0321453
SFTPA2 surfactant protein A2 0.0321113
SPC25 SPC25, NDC80 kinetochore complex component 0.0319368
UNC13D unc-13 homolog D (C. elegans) 0.0319052
HBG1 hemoglobin, gamma A 0.0317219
SPAG9 sperm associated antigen 9 0.0316515
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0316409
LMAN1 lectin, mannose-binding, 1 0.0313932
TMEM267 transmembrane protein 267 0.0313472
KAT6B K(lysine) acetyltransferase 6B 0.031283
GLCCI1 glucocorticoid induced 1 0.0311988
AHI1 Abelson helper integration site 1 0.031124
ESRRB estrogen-related receptor beta 0.0310695
SERGEF secretion regulating guanine nucleotide exchange factor 0.0309864
TBCK TBC1 domain containing kinase 0.0306686
SORT1 sortilin 1 0.0306131
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0305252
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0304783
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0304016
TUSC3 tumor suppressor candidate 3 0.0303939
NAP1L1 nucleosome assembly protein 1-like 1 0.0302846
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0302395
WASL Wiskott-Aldrich syndrome-like 0.0300996
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0300459
BABAM2 BRISC and BRCA1 A complex member 2 0.0300234
SQSTM1 sequestosome 1 0.029697
CARD11 caspase recruitment domain family, member 11 0.0296377
MYH10 myosin, heavy chain 10, non-muscle 0.029473
INO80 INO80 complex subunit 0.0294534
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.0291834
EXOC4 exocyst complex component 4 0.029156
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.029143
WDFY3 WD repeat and FYVE domain containing 3 0.0291041
AGO3 argonaute RISC catalytic component 3 0.0288769
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.0286039
CALN1 calneuron 1 0.0286033
CHD6 chromodomain helicase DNA binding protein 6 0.0285868
IMMT inner membrane protein, mitochondrial 0.0285067
BTBD9 BTB (POZ) domain containing 9 0.0284774
MKI67 marker of proliferation Ki-67 0.0284204
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0283961
IGF2R insulin-like growth factor 2 receptor 0.0283901
TMEM135 transmembrane protein 135 0.028186
NLK nemo-like kinase 0.0281765
TTC1 tetratricopeptide repeat domain 1 0.028098
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.0280904
DLG5 discs, large homolog 5 (Drosophila) 0.0280838
KHSRP KH-type splicing regulatory protein 0.0280117
METTL15 methyltransferase like 15 0.0279705
MTDH metadherin 0.0278841
CEP350 centrosomal protein 350kDa 0.0278122
ARHGAP15 Rho GTPase activating protein 15 0.0277636
IWS1 IWS1 homolog (S. cerevisiae) 0.0276291
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.0276031
PTH2R parathyroid hormone 2 receptor 0.0275425
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.0275317
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0273897
NACA nascent polypeptide-associated complex alpha subunit 0.0273002
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0272505
ANKRD10 ankyrin repeat domain 10 0.027228
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.0271664
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0271489
USP15 ubiquitin specific peptidase 15 0.0271234
KAZN kazrin, periplakin interacting protein 0.0269223
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.0268989
IARS1 isoleucyl-tRNA synthetase 1 0.0268468
ENOSF1 enolase superfamily member 1 0.0268331
RPL37 ribosomal protein L37 0.0268264
DMWD dystrophia myotonica, WD repeat containing 0.0267572
NCAM2 neural cell adhesion molecule 2 0.0267098
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.0266972
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.026647
SNX13 sorting nexin 13 0.0265449
LMAN2L lectin, mannose-binding 2-like 0.0265426
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0264425
DMD dystrophin 0.0263929
DNAH14 dynein, axonemal, heavy chain 14 0.0263373
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.0262732
CSDE1 cold shock domain containing E1, RNA-binding 0.0262425
GSK3B glycogen synthase kinase 3 beta 0.0262211
BRWD1 bromodomain and WD repeat domain containing 1 0.0262068
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0261349
TGFBR3 transforming growth factor, beta receptor III 0.0261277
ARID1A AT rich interactive domain 1A (SWI-like) 0.0260822
MAP2K5 mitogen-activated protein kinase kinase 5 0.0260623
NUP160 nucleoporin 160kDa 0.0260586
CLINT1 clathrin interactor 1 0.0259634
ATAD2 ATPase family, AAA domain containing 2 0.0259333
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0258527
LATS1 large tumor suppressor kinase 1 0.0257847
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.0257669
TRPS1 trichorhinophalangeal syndrome I 0.0257137
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0256814
ATP11C ATPase, class VI, type 11C 0.0256513
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0254537
RAI14 retinoic acid induced 14 0.0254534
DNA2 DNA replication helicase/nuclease 2 0.0254159
SLC38A2 solute carrier family 38, member 2 0.0252204
FCHSD2 FCH and double SH3 domains 2 0.0251453
ZFAT zinc finger and AT hook domain containing 0.0251237
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0250906
FAM120A family with sequence similarity 120A 0.0249039
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0248975
COPA coatomer protein complex, subunit alpha 0.0247962
RPS19 ribosomal protein S19 0.0247824
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.0246733
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0246454
AKAP12 A kinase (PRKA) anchor protein 12 0.0245624
PEAK1 pseudopodium-enriched atypical kinase 1 0.0243386
POLK polymerase (DNA directed) kappa 0.0242621
CCAR1 cell division cycle and apoptosis regulator 1 0.0241512
MYSM1 Myb-like, SWIRM and MPN domains 1 0.0241329
UHMK1 U2AF homology motif (UHM) kinase 1 0.0240699
STRN striatin, calmodulin binding protein 0.0240458
WNT5B wingless-type MMTV integration site family, member 5B 0.0239923
SNX4 sorting nexin 4 0.0239915
DYM dymeclin 0.0239626
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.0239357
MSH3 mutS homolog 3 0.0238346
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.0237267
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.0237194
U2SURP U2 snRNP-associated SURP domain containing 0.0235965
TBC1D5 TBC1 domain family, member 5 0.0235809
NPR2 natriuretic peptide receptor 2 0.0235794
NFE2L2 nuclear factor, erythroid 2-like 2 0.0235613
SRSF11 serine/arginine-rich splicing factor 11 0.023539
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0234418
TPX2 TPX2, microtubule-associated 0.0233753
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.0233654
MAP2K1 mitogen-activated protein kinase kinase 1 0.0233339
MARCHF7 membrane associated ring-CH-type finger 7 0.0232856
TMCC1 transmembrane and coiled-coil domain family 1 0.0232792
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0231614
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0231038
RBBP7 retinoblastoma binding protein 7 0.0230879
ACIN1 apoptotic chromatin condensation inducer 1 0.0230794
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0230549
R3HDM2 R3H domain containing 2 0.023019
WDR70 WD repeat domain 70 0.023013
FANCA Fanconi anemia, complementation group A 0.0229169
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.0228802
EIF4E eukaryotic translation initiation factor 4E 0.0228649
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0227412
ANKRD28 ankyrin repeat domain 28 0.0227314
NUP62 nucleoporin 62kDa 0.0226706
RBM33 RNA binding motif protein 33 0.0226144
ZER1 zyg-11 related, cell cycle regulator 0.0225891
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0225549
PEX13 peroxisomal biogenesis factor 13 0.0225072
TIAM2 T-cell lymphoma invasion and metastasis 2 0.0224907
ANO10 anoctamin 10 0.0224895
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0223289
NUCB2 nucleobindin 2 0.0222515
SEC31A SEC31 homolog A (S. cerevisiae) 0.022168
RPAIN RPA interacting protein 0.0221384
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0220524
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.0219694
GRB10 growth factor receptor-bound protein 10 0.0219539
ARF1 ADP-ribosylation factor 1 0.0219178
RSRP1 arginine/serine-rich protein 1 0.0219144
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.0219075
SPIDR scaffolding protein involved in DNA repair 0.0218946
SFXN5 sideroflexin 5 0.0218493
NEB nebulin 0.0218386
LIMA1 LIM domain and actin binding 1 0.021782
MFSD2B major facilitator superfamily domain containing 2B 0.02177
JARID2 jumonji, AT rich interactive domain 2 0.0217617
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.0217452
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0217177
INTS7 integrator complex subunit 7 0.021669
KIF1B kinesin family member 1B 0.0216641
TMEM108 transmembrane protein 108 0.0216531
ZMYND11 zinc finger, MYND-type containing 11 0.0216143
OXCT1 3-oxoacid CoA transferase 1 0.0216098
NSUN4 NOP2/Sun domain family, member 4 0.0216081
PCGF6 polycomb group ring finger 6 0.0215241
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.0214955
HIPK3 homeodomain interacting protein kinase 3 0.0214023
EIF3J eukaryotic translation initiation factor 3, subunit J 0.0213829
SACS sacsin molecular chaperone 0.0213422
PDS5A PDS5 cohesin associated factor A 0.0213404
CFAP161 cilia and flagella associated protein 161 0.0213077
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.0213033
TUBB tubulin, beta class I 0.0212806
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.021276
EXOC6B exocyst complex component 6B 0.0212621
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.0211185
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.021058
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0210241
PARD3B par-3 family cell polarity regulator beta 0.0210108
SAMD4A sterile alpha motif domain containing 4A 0.0209983
BTBD1 BTB (POZ) domain containing 1 0.0209527
LMNA lamin A/C 0.0208914
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0207728
STIM2 stromal interaction molecule 2 0.0207384
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0207279
CD2AP CD2-associated protein 0.020692
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0206852
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0206775
AVL9 AVL9 homolog (S. cerevisiase) 0.0206707
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0206472
ENDOD1 endonuclease domain containing 1 0.0205873
RESF1 retroelement silencing factor 1 0.0205557
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0205334
DROSHA drosha, ribonuclease type III 0.0205213
TXNDC11 thioredoxin domain containing 11 0.0205086
CCDC6 coiled-coil domain containing 6 0.0204823
GALK2 galactokinase 2 0.0204672
MED13L mediator complex subunit 13-like 0.0203668
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.0203109
DEXI Dexi homolog (mouse) 0.0203046
SIMC1 SUMO-interacting motifs containing 1 0.0202928
ANKLE2 ankyrin repeat and LEM domain containing 2 0.0202712
ZC3H13 zinc finger CCCH-type containing 13 0.020247
USP6NL USP6 N-terminal like 0.0202439
ARHGAP17 Rho GTPase activating protein 17 0.0200938
USP3 ubiquitin specific peptidase 3 0.0200363
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.0200357
NEK7 NIMA-related kinase 7 0.0200239
UBE2I ubiquitin-conjugating enzyme E2I 0.0200063
COMMD1 copper metabolism (Murr1) domain containing 1 0.0199333
DCAKD dephospho-CoA kinase domain containing 0.0198773
STK38 serine/threonine kinase 38 0.0197186
PRKCB protein kinase C, beta 0.0195511
TPST2 tyrosylprotein sulfotransferase 2 0.019543
AFG1L AFG1 like ATPase 0.0195321
MSH2 mutS homolog 2 0.0195301
RNF115 ring finger protein 115 0.0195172
RIOX2 ribosomal oxygenase 2 0.0194369
RNASE3 ribonuclease, RNase A family, 3 0.0194256
CEP76 centrosomal protein 76kDa 0.0194093
CARM1 coactivator-associated arginine methyltransferase 1 0.0194069
NUP188 nucleoporin 188kDa 0.019354
WWC2 WW and C2 domain containing 2 0.0193104
TEC tec protein tyrosine kinase 0.0193098
CCNF cyclin F 0.0192061
ELP4 elongator acetyltransferase complex subunit 4 0.0191694
STIM1 stromal interaction molecule 1 0.019132
DNPEP aspartyl aminopeptidase 0.0190809
CFAP20DC CFAP20 domain containing 0.0190028
NUP205 nucleoporin 205kDa 0.0189882
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 0.0189828
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0189753
PLXDC2 plexin domain containing 2 0.018899
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0188864
EIF3A eukaryotic translation initiation factor 3, subunit A 0.01877
RORA RAR-related orphan receptor A 0.0187676
SPRED2 sprouty-related, EVH1 domain containing 2 0.0187659
C4ORF36 chromosome 4 open reading frame 36 0.0187375
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 0.0187252
LTBP1 latent transforming growth factor beta binding protein 1 0.0187059
BARD1 BRCA1 associated RING domain 1 0.0186946
SRSF4 serine/arginine-rich splicing factor 4 0.0186736
GCC2 GRIP and coiled-coil domain containing 2 0.0186612
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.0186412
TUT4 terminal uridylyl transferase 4 0.0186171
TIMP1 TIMP metallopeptidase inhibitor 1 0.0185941
UNK unkempt family zinc finger 0.0185901
F8 coagulation factor VIII, procoagulant component 0.0185813
ACBD6 acyl-CoA binding domain containing 6 0.01856
ARL13B ADP-ribosylation factor-like 13B 0.0185065
SMC4 structural maintenance of chromosomes 4 0.0184991
TMEM63A transmembrane protein 63A 0.0184991
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0184679
HDAC5 histone deacetylase 5 0.0184171
PARD3 par-3 family cell polarity regulator 0.0184144
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0184069
DHDDS dehydrodolichyl diphosphate synthase 0.0184024
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.0183143
SCAP SREBF chaperone 0.018306
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.0181816
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0181724
DOCK9 dedicator of cytokinesis 9 0.0181626
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.0180951
CANX calnexin 0.0180871
RPL23 ribosomal protein L23 0.0180849
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0179729
CREB5 cAMP responsive element binding protein 5 0.0179392
ELMO1 engulfment and cell motility 1 0.0179291
RPL35 ribosomal protein L35 0.0179057
PHF20 PHD finger protein 20 0.0178925
UBN1 ubinuclein 1 0.0178906
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.0178717
TRIP4 thyroid hormone receptor interactor 4 0.0178395
CYBA cytochrome b-245, alpha polypeptide 0.0177418
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.0177415
NCOR2 nuclear receptor corepressor 2 0.0176762
NCAPD3 non-SMC condensin II complex, subunit D3 0.017582
WEE1 WEE1 G2 checkpoint kinase 0.0175781
SATB2 SATB homeobox 2 0.0175749
LCLAT1 lysocardiolipin acyltransferase 1 0.0175226
PRAME preferentially expressed antigen in melanoma 0.0174304
TMEM33 transmembrane protein 33 0.0174185
PTPRC protein tyrosine phosphatase, receptor type, C 0.0174071
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.0173678
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.0173634
RBBP6 retinoblastoma binding protein 6 0.0173405
PANK2 pantothenate kinase 2 0.0173276
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0173011
SCAF4 SR-related CTD-associated factor 4 0.0172916
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0172912
SCAMP2 secretory carrier membrane protein 2 0.0172889
SMAD2 SMAD family member 2 0.0171855
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0171248
RHOT1 ras homolog family member T1 0.0171237
ZNF124 zinc finger protein 124 0.0171138
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0170986
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0170945
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0170829
FBXO42 F-box protein 42 0.0170805
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0170764
GCLC glutamate-cysteine ligase, catalytic subunit 0.0170533
ADGRL1 adhesion G protein-coupled receptor L1 0.0170241
NRXN3 neurexin 3 0.0170034
MBTD1 mbt domain containing 1 0.016963
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.0169596
CMC1 C-x(9)-C motif containing 1 0.0169461
HIC2 hypermethylated in cancer 2 0.0169421
YBX1 Y box binding protein 1 0.0169363
CISD1 CDGSH iron sulfur domain 1 0.016931
PNN pinin, desmosome associated protein 0.0168952
DCAF16 DDB1 and CUL4 associated factor 16 0.0168864
DPEP2 dipeptidase 2 0.0168703
SELENOT selenoprotein T 0.0167534
KIZ kizuna centrosomal protein 0.0167474
TCEA1 transcription elongation factor A (SII), 1 0.0166896
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.0166622
EEA1 early endosome antigen 1 0.016661
ARHGAP35 Rho GTPase activating protein 35 0.0166097
HMBS hydroxymethylbilane synthase 0.0165826
NOL10 nucleolar protein 10 0.0165546
ELP6 elongator acetyltransferase complex subunit 6 0.0165454
TCF20 transcription factor 20 (AR1) 0.0165434
LRRC41 leucine rich repeat containing 41 0.0165353
DENND4A DENN/MADD domain containing 4A 0.0165351
RPS9 ribosomal protein S9 0.0165291
XPO4 exportin 4 0.0165082
DIAPH3 diaphanous-related formin 3 0.0164953
TOMM70 translocase of outer mitochondrial membrane 70 0.0164555
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.0164432
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.0164258
TNPO1 transportin 1 0.0164035
COTL1 coactosin-like F-actin binding protein 1 0.0163757
ZBTB38 zinc finger and BTB domain containing 38 0.0163414
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.0163234
PKN1 protein kinase N1 0.0163142
CIRSR corepressor of RBPJ and splicing regulator 0.0163112
BTNL9 butyrophilin-like 9 0.0162742
CRY1 cryptochrome circadian clock 1 0.0162605
MTIF2 mitochondrial translational initiation factor 2 0.0162261
PRPF38B pre-mRNA processing factor 38B 0.0162239
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0162059
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0161174
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0160916
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.0160786
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 0.01607
TRIR telomerase RNA component interacting RNase 0.0160463
MTERF1 mitochondrial transcription termination factor 1 0.0160196
TNPO3 transportin 3 0.016012
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.0159942
ETFDH electron-transferring-flavoprotein dehydrogenase 0.0159376
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 0.0159275
KCTD20 potassium channel tetramerization domain containing 20 0.0159216
TMEM63B transmembrane protein 63B 0.0159042
DGLUCY D-glutamate cyclase 0.0158841
LITAF lipopolysaccharide-induced TNF factor 0.0158829
CUL1 cullin 1 0.0158768
SLC38A10 solute carrier family 38, member 10 0.0157795
MTF2 metal response element binding transcription factor 2 0.0157653
TOM1L2 target of myb1-like 2 (chicken) 0.0157331
OSBPL8 oxysterol binding protein-like 8 0.0156785
WDR59 WD repeat domain 59 0.0156751
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0156657
JAK1 Janus kinase 1 0.0156607
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.0156515
SCYL3 SCY1-like 3 (S. cerevisiae) 0.0156402
COX7C cytochrome c oxidase subunit VIIc 0.0156132
NKTR natural killer cell triggering receptor 0.015599
ABHD2 abhydrolase domain containing 2 0.0155343
DCAF1 DDB1 and CUL4 associated factor 1 0.0155308
STIL SCL/TAL1 interrupting locus 0.0154471
SMAP1 small ArfGAP 1 0.0154397
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0154385
SEPTIN9 septin 9 0.015435
CHTOP chromatin target of PRMT1 0.015421
PCDHB16 protocadherin beta 16 0.0153755
NCAPG non-SMC condensin I complex, subunit G 0.0153565
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.0153491
FOXRED2 FAD-dependent oxidoreductase domain containing 2 0.0153487
NME7 NME/NM23 family member 7 0.0153229
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.015322
SRGN serglycin 0.0152974
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 0.0152879
MOSMO modulator of smoothened 0.0152688
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0152672
ZFC3H1 zinc finger, C3H1-type containing 0.0152616
RPLP2 ribosomal protein, large, P2 0.0152472
TRABD TraB domain containing 0.0152458
WWOX WW domain containing oxidoreductase 0.0152407
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.0152349
YIPF4 Yip1 domain family, member 4 0.0152241
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0152169
CAPN2 calpain 2, (m/II) large subunit 0.015206
CCSER2 coiled-coil serine-rich protein 2 0.0151683
TNRC6B trinucleotide repeat containing 6B 0.0151562
RBL1 retinoblastoma-like 1 0.0151462
ZNF106 zinc finger protein 106 0.0151246
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.0151243
CREBRF CREB3 regulatory factor 0.0151228
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.0151146
PTBP2 polypyrimidine tract binding protein 2 0.0151121
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.0150835
GDF11 growth differentiation factor 11 0.0150543
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0150111
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.0150094
XPOT exportin, tRNA 0.0149575
ZNF639 zinc finger protein 639 0.0149486
ELOVL5 ELOVL fatty acid elongase 5 0.0149486
COPZ1 coatomer protein complex, subunit zeta 1 0.0149484
IGSF1 immunoglobulin superfamily, member 1 0.0149305
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.0149295
FLOT2 flotillin 2 0.0149289
SLMAP sarcolemma associated protein 0.0149136
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0149053

decreased expression

Symbol Name Standardized Value
KIF13A kinesin family member 13A -0.0671996
ENO1 enolase 1, (alpha) -0.0642066
PRKCA protein kinase C, alpha -0.0582321
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0556764
NUMB numb homolog (Drosophila) -0.0548525
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0547614
C6ORF89 chromosome 6 open reading frame 89 -0.0544979
SETD2 SET domain containing 2 -0.0534858
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0534428
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0531668
SRRM2 serine/arginine repetitive matrix 2 -0.0531339
CCDC91 coiled-coil domain containing 91 -0.0520081
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0512119
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0499945
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0484904
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0476461
KDM2A lysine (K)-specific demethylase 2A -0.045298
KLHDC10 kelch domain containing 10 -0.0446612
KRT8 keratin 8, type II -0.0437846
NGLY1 N-glycanase 1 -0.0429001
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0427636
PKM pyruvate kinase, muscle -0.0422058
BMP2K BMP2 inducible kinase -0.0419453
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0418154
SRPK1 SRSF protein kinase 1 -0.0415593
ACTN4 actinin, alpha 4 -0.0407285
CHD4 chromodomain helicase DNA binding protein 4 -0.0406651
LARP1 La ribonucleoprotein domain family, member 1 -0.040501
VCL vinculin -0.0404323
MAPK1 mitogen-activated protein kinase 1 -0.0402211
CTBP2 C-terminal binding protein 2 -0.0400282
CLTC clathrin, heavy chain (Hc) -0.0397327
MACF1 microtubule-actin crosslinking factor 1 -0.0396417
RACK1 receptor for activated C kinase 1 -0.0393206
SON SON DNA binding protein -0.0391515
HBG2 hemoglobin, gamma G -0.0391338
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0389937
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0382224
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0378423
DLG1 discs, large homolog 1 (Drosophila) -0.0378024
CUX1 cut-like homeobox 1 -0.0373825
INSIG1 insulin induced gene 1 -0.0369948
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0367534
SNX14 sorting nexin 14 -0.0366458
SZRD1 SUZ RNA binding domain containing 1 -0.0365867
AK1 adenylate kinase 1 -0.0365505
NALF1 NALCN channel auxiliary factor 1 -0.0365494
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0363375
RELN reelin -0.0362651
UBE4B ubiquitination factor E4B -0.036186
RCOR1 REST corepressor 1 -0.0359921
NSD1 nuclear receptor binding SET domain protein 1 -0.035725
MEIS2 Meis homeobox 2 -0.0351631
EIF5B eukaryotic translation initiation factor 5B -0.0349493
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0345066
AOPEP aminopeptidase O (putative) -0.0342679
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.034262
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0340381
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0340036
JMJD1C jumonji domain containing 1C -0.0335381
MACC1 metastasis associated in colon cancer 1 -0.0334884
WASF2 WAS protein family, member 2 -0.0332558
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.032981
RPS8 ribosomal protein S8 -0.0329701
LCORL ligand dependent nuclear receptor corepressor-like -0.0329166
KSR1 kinase suppressor of ras 1 -0.0328446
MACO1 macoilin 1 -0.0327416
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0326502
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0323013
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0322446
ACOD1 aconitate decarboxylase 1 -0.0322057
ZNF148 zinc finger protein 148 -0.0321236
TMEM181 transmembrane protein 181 -0.0321145
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0318825
CD46 CD46 molecule, complement regulatory protein -0.0315709
NF1 neurofibromin 1 -0.0315636
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0313304
TNPO2 transportin 2 -0.0313242
AHCTF1 AT hook containing transcription factor 1 -0.0305849
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0305537
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -0.0303901
SQLE squalene epoxidase -0.0303864
FLNA filamin A, alpha -0.0303589
NMT1 N-myristoyltransferase 1 -0.0302637
SRPK2 SRSF protein kinase 2 -0.0301854
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0301542
MARCHF3 membrane associated ring-CH-type finger 3 -0.0299754
EPB41 erythrocyte membrane protein band 4.1 -0.0299246
TMEM131L transmembrane 131 like -0.0296897
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0296659
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0295696
INVS inversin -0.0295296
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.029326
ADGRE5 adhesion G protein-coupled receptor E5 -0.0292683
SLC39A11 solute carrier family 39, member 11 -0.0292675
ESYT2 extended synaptotagmin-like protein 2 -0.0292505
FAM13B family with sequence similarity 13, member B -0.0291926
FBXL20 F-box and leucine-rich repeat protein 20 -0.0290807
HMGA1 high mobility group AT-hook 1 -0.0290514
SERF2 small EDRK-rich factor 2 -0.0289454
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0289385
LOC112694756 uncharaterized LOC112694756 -0.0288532
EZR ezrin -0.0287001
PUM2 pumilio RNA-binding family member 2 -0.0286154
FDPS farnesyl diphosphate synthase -0.0284252
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0282934
AMBRA1 autophagy/beclin-1 regulator 1 -0.0282725
TGOLN2 trans-golgi network protein 2 -0.0281678
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0279343
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0279304
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0277964
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0277716
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.0276445
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0275181
NDC1 NDC1 transmembrane nucleoporin -0.0273353
CHKA choline kinase alpha -0.0272042
SMC6 structural maintenance of chromosomes 6 -0.0271388
KIAA0232 KIAA0232 -0.0271277
PRKCSH protein kinase C substrate 80K-H -0.0270611
GGNBP2 gametogenetin binding protein 2 -0.0270261
TRAPPC10 trafficking protein particle complex 10 -0.0269294
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0269263
NRDC nardilysin convertase -0.0269073
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.0268999
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.0268924
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0268924
SRRM1 serine/arginine repetitive matrix 1 -0.0268225
MUSK muscle, skeletal, receptor tyrosine kinase -0.0267413
ECPAS Ecm29 proteasome adaptor and scaffold -0.0266682
BSG basigin (Ok blood group) -0.0265852
RCSD1 RCSD domain containing 1 -0.0264364
RPL6 ribosomal protein L6 -0.0264141
AFF4 AF4/FMR2 family, member 4 -0.0263968
KMT2C lysine (K)-specific methyltransferase 2C -0.0263379
PRR14L proline rich 14-like -0.0261997
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.0261868
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.0260744
TTC17 tetratricopeptide repeat domain 17 -0.0260658
SINHCAF SIN3-HDAC complex associated factor -0.0257863
ARL15 ADP-ribosylation factor-like 15 -0.0257739
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -0.0255189
MCU mitochondrial calcium uniporter -0.025316
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0252563
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.0250739
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0250728
KAT2B K(lysine) acetyltransferase 2B -0.0250716
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0250672
MLXIP MLX interacting protein -0.0250497
TOP3B topoisomerase (DNA) III beta -0.0250059
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.024772
TMEM165 transmembrane protein 165 -0.0247642
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0247639
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.024695
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.0246902
ZNF83 zinc finger protein 83 -0.0246425
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0246111
RETREG3 reticulophagy regulator family member 3 -0.0245093
DEAF1 DEAF1 transcription factor -0.0245086
HBE1 hemoglobin, epsilon 1 -0.0243584
LDHA lactate dehydrogenase A -0.024339
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0243222
PPHLN1 periphilin 1 -0.0242411
ATP13A3 ATPase type 13A3 -0.0242104
SETD5 SET domain containing 5 -0.0241774
WDR26 WD repeat domain 26 -0.0241272
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0240592
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0240099
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.024009
FAM120B family with sequence similarity 120B -0.0238944
POM121 POM121 transmembrane nucleoporin -0.0238805
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -0.0238319
TBCE tubulin folding cofactor E -0.0237324
ACO2 aconitase 2, mitochondrial -0.0237122
POTEF POTE ankyrin domain family, member F -0.0236715
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0235464
TMEM131 transmembrane protein 131 -0.0233921
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.0233903
HBA1 hemoglobin, alpha 1 -0.0233572
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.0233421
LUZP1 leucine zipper protein 1 -0.023293
TPM3 tropomyosin 3 -0.0231651
CLASP1 cytoplasmic linker associated protein 1 -0.0230185
GATD1 glutamine amidotransferase class 1 domain containing 1 -0.0229756
EPHB6 EPH receptor B6 -0.0229344
KARS1 lysyl-tRNA synthetase 1 -0.0228585
RSBN1L round spermatid basic protein 1-like -0.0228141
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.0227908
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0227746
BST2 bone marrow stromal cell antigen 2 -0.0227609
PTK2 protein tyrosine kinase 2 -0.0227447
FHIT fragile histidine triad -0.0227113
TRRAP transformation/transcription domain-associated protein -0.0226992
USP47 ubiquitin specific peptidase 47 -0.0226512
RPLP0 ribosomal protein, large, P0 -0.0226441
RPL10A ribosomal protein L10a -0.0226096
RNF149 ring finger protein 149 -0.0225895
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0225373
NOP58 NOP58 ribonucleoprotein -0.0225048
ZNF367 zinc finger protein 367 -0.0223519
NCOA3 nuclear receptor coactivator 3 -0.0223393
WDR44 WD repeat domain 44 -0.0223179
FAM178B family with sequence similarity 178, member B -0.022302
AKAP9 A kinase (PRKA) anchor protein 9 -0.0222958
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0222553
GNAS GNAS complex locus -0.0222158
GMPS guanine monphosphate synthase -0.0222076
SENP5 SUMO1/sentrin specific peptidase 5 -0.0221333
RPL37A ribosomal protein L37a -0.0221089
TMEM50A transmembrane protein 50A -0.0220927
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0220825
MVD mevalonate (diphospho) decarboxylase -0.0219723
CCM2 cerebral cavernous malformation 2 -0.0219281
LMBR1 limb development membrane protein 1 -0.0218513
SEC11A SEC11 homolog A (S. cerevisiae) -0.0218491
TOP2B topoisomerase (DNA) II beta 180kDa -0.0218312
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0217059
CERT1 ceramide transporter 1 -0.0216681
DTNBP1 dystrobrevin binding protein 1 -0.0215182
FRS2 fibroblast growth factor receptor substrate 2 -0.0215126
ANGPT1 angiopoietin 1 -0.0215018
PTPRJ protein tyrosine phosphatase, receptor type, J -0.0214654
CD44 CD44 molecule (Indian blood group) -0.0214455
NUP153 nucleoporin 153kDa -0.0214165
RAD23B RAD23 homolog B (S. cerevisiae) -0.021376
RPS12 ribosomal protein S12 -0.0213729
TNRC18 trinucleotide repeat containing 18 -0.0213505
NUP155 nucleoporin 155kDa -0.0213061
MRPS10 mitochondrial ribosomal protein S10 -0.0211343
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.0210696
MCM4 minichromosome maintenance complex component 4 -0.0210638
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -0.0209022
CHD1 chromodomain helicase DNA binding protein 1 -0.0208974
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0208622
CDK17 cyclin-dependent kinase 17 -0.0208333
RPL13A ribosomal protein L13a -0.0207708
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0207438
RNF217 ring finger protein 217 -0.0207318
PANK3 pantothenate kinase 3 -0.0206039
KRIT1 KRIT1, ankyrin repeat containing -0.0205872
TSG101 tumor susceptibility 101 -0.0205683
GON4L gon-4-like (C. elegans) -0.020567
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0205502
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0205355
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0205072
THEM4 thioesterase superfamily member 4 -0.020463
TANGO2 transport and golgi organization 2 homolog (Drosophila) -0.0204553
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0203341
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0202798
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0202788
MAP1B microtubule-associated protein 1B -0.0201893
CORO2A coronin, actin binding protein, 2A -0.0201223
ACTG1 actin gamma 1 -0.0200882
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0200778
FTH1 ferritin, heavy polypeptide 1 -0.0200642
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0200393
SACK1A scaffolding CK1 anchoring protein A -0.0200322
CUL3 cullin 3 -0.0199756
MRRF mitochondrial ribosome recycling factor -0.0199021
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0198793
TFRC transferrin receptor -0.0198784
MMS22L MMS22-like, DNA repair protein -0.0198554
ATL2 atlastin GTPase 2 -0.0197551
GOLM2 golgi membrane protein 2 -0.0197538
STRN3 striatin, calmodulin binding protein 3 -0.0197063
GDNF glial cell derived neurotrophic factor -0.0196956
KCMF1 potassium channel modulatory factor 1 -0.0196954
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0196537
RPLP1 ribosomal protein, large, P1 -0.0196074
PPME1 protein phosphatase methylesterase 1 -0.0195268
HMGB1 high mobility group box 1 -0.0195092
KCTD11 potassium channel tetramerization domain containing 11 -0.0194971
NPTN neuroplastin -0.019484
SOS1 son of sevenless homolog 1 (Drosophila) -0.0194787
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.019443
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.0194391
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.0194173
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0194012
KIFC3 kinesin family member C3 -0.0193551
PNISR PNN-interacting serine/arginine-rich protein -0.0193506
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -0.0193262
CTPS1 CTP synthase 1 -0.0193241
SERP1 stress-associated endoplasmic reticulum protein 1 -0.0192666
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0192026
MYO3B myosin IIIB -0.019121
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0191149
MAP4 microtubule-associated protein 4 -0.0190786
ZEB2 zinc finger E-box binding homeobox 2 -0.0190759
STRBP spermatid perinuclear RNA binding protein -0.0190595
ADD3 adducin 3 (gamma) -0.0190566
DPP8 dipeptidyl-peptidase 8 -0.0190505
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -0.0190478
ADD1 adducin 1 (alpha) -0.0190338
ACER3 alkaline ceramidase 3 -0.018992
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0189901
FRRS1 ferric-chelate reductase 1 -0.0189061
MRPS18B mitochondrial ribosomal protein S18B -0.0189022
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0188932
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) -0.0188695
CCDC88A coiled-coil domain containing 88A -0.018683
OIP5 Opa interacting protein 5 -0.0186785
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0186
CELF1 CUGBP, Elav-like family member 1 -0.01856
CALR calreticulin -0.0185306
KDM5A lysine (K)-specific demethylase 5A -0.0185265
ZNF721 zinc finger protein 721 -0.0184769
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.01847
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.0182227
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0182001
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.0181591
CEP295 centrosomal protein 295kDa -0.0181465
TLN1 talin 1 -0.0181225
SSBP4 single stranded DNA binding protein 4 -0.0180675
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.0180652
NUP214 nucleoporin 214kDa -0.0180352
HSPA4 heat shock 70kDa protein 4 -0.0179947
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0179726
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0179555
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0179386
KMT5B lysine methyltransferase 5B -0.0179146
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -0.0179144
CCDC47 coiled-coil domain containing 47 -0.0179119
OGG1 8-oxoguanine DNA glycosylase -0.0178548
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0178338
PARN poly(A)-specific ribonuclease -0.0178273
PAIP2 poly(A) binding protein interacting protein 2 -0.0178195
GLO1 glyoxalase I -0.0177907
FAM162A family with sequence similarity 162, member A -0.0177654
MTPN myotrophin -0.0177443
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -0.0177405
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.017735
GLUL glutamate-ammonia ligase -0.0177122
CNKSR3 CNKSR family member 3 -0.0177076
ZNF655 zinc finger protein 655 -0.0176993
TUBA1C tubulin, alpha 1c -0.0176966
ERP44 endoplasmic reticulum protein 44 -0.0176926
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0176281
TPCN1 two pore segment channel 1 -0.017612
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0175554
SNX8 sorting nexin 8 -0.0175281
CHD7 chromodomain helicase DNA binding protein 7 -0.0175116
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.017503
GMCL1 germ cell-less, spermatogenesis associated 1 -0.0174831
ARV1 ARV1 homolog (S. cerevisiae) -0.0174802
NUDC nudC nuclear distribution protein -0.0174604
BRD2 bromodomain containing 2 -0.017445
CDK7 cyclin-dependent kinase 7 -0.0174448
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 -0.0174178
MACROH2A1 macroH2A.1 histone -0.0173598
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.017354
UBE3D ubiquitin protein ligase E3D -0.0173373
ZNF445 zinc finger protein 445 -0.0173009
STAT5B signal transducer and activator of transcription 5B -0.0172779
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0172763
CBX5 chromobox homolog 5 -0.0172731
HMGXB3 HMG box domain containing 3 -0.0172439
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -0.0172404
HSPB1 heat shock 27kDa protein 1 -0.0172251
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.0171981
SETDB1 SET domain, bifurcated 1 -0.0170871
ERI3 ERI1 exoribonuclease family member 3 -0.0170664
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0170503
GPHN gephyrin -0.0170466
MRPS27 mitochondrial ribosomal protein S27 -0.0170267
GCLM glutamate-cysteine ligase, modifier subunit -0.0170224
CREBBP CREB binding protein -0.0170099
ANXA2 annexin A2 -0.0170059
TXNRD2 thioredoxin reductase 2 -0.0169757
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0169586
TKT transketolase -0.0169212
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0169079
TMEM123 transmembrane protein 123 -0.0169063
FBH1 F-box DNA helicase 1 -0.0168527
PDCD6IP programmed cell death 6 interacting protein -0.0168355
ZC3H4 zinc finger CCCH-type containing 4 -0.0168081
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.0167783
FLNB filamin B, beta -0.016771
CATSPERB catsper channel auxiliary subunit beta -0.0167353
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0167223
H1-10 H1.10 linker histone -0.0167164
MAML3 mastermind-like 3 (Drosophila) -0.0167092
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0166669
KIF16B kinesin family member 16B -0.0166643
LIAS lipoic acid synthetase -0.0166256
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -0.0165761
FKBP5 FK506 binding protein 5 -0.0165604
BCL2L1 BCL2-like 1 -0.0165471
ZZZ3 zinc finger, ZZ-type containing 3 -0.0165403
NF2 neurofibromin 2 (merlin) -0.0165199
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.0164896
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.0164759
ERCC8 excision repair cross-complementation group 8 -0.0164414
EIF1 eukaryotic translation initiation factor 1 -0.0164254
UBE2H ubiquitin-conjugating enzyme E2H -0.0163928
TFCP2 transcription factor CP2 -0.0163695
CERS6 ceramide synthase 6 -0.016301
LSG1 large 60S subunit nuclear export GTPase 1 -0.0162584
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0162182
RRP1B ribosomal RNA processing 1B -0.0161826
RHBDD1 rhomboid domain containing 1 -0.0161799
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -0.0161652
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -0.0161571
CREG1 cellular repressor of E1A-stimulated genes 1 -0.0161284
CAB39 calcium binding protein 39 -0.0161252
IPO11 importin 11 -0.0161213
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -0.0161064
SLC35D4 solute carrier family 35 member D4 -0.0161008
CDK12 cyclin-dependent kinase 12 -0.0160991
UBAP2L ubiquitin associated protein 2-like -0.0160934
RNF130 ring finger protein 130 -0.0160871
CNN2 calponin 2 -0.0160652
FBXO17 F-box protein 17 -0.0160435
GMDS GDP-mannose 4,6-dehydratase -0.0159912
ZBTB11 zinc finger and BTB domain containing 11 -0.015979
NFIA nuclear factor I/A -0.0159719
KLHL24 kelch-like family member 24 -0.0159715
YME1L1 YME1-like 1 ATPase -0.0159481
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 -0.0158787
PWWP2A PWWP domain containing 2A -0.01579
TALDO1 transaldolase 1 -0.0157752
OGA O-GlcNAcase -0.0157654
STXBP1 syntaxin binding protein 1 -0.0157618
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.0157564
RPL30 ribosomal protein L30 -0.0156995
TAOK3 TAO kinase 3 -0.0156746
CRLF3 cytokine receptor-like factor 3 -0.0156505
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -0.015647
PRDX5 peroxiredoxin 5 -0.0156369
BICD1 bicaudal D homolog 1 (Drosophila) -0.0156335
DCAF10 DDB1 and CUL4 associated factor 10 -0.0156326
PTEN phosphatase and tensin homolog -0.0156237
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) -0.0156037
PUM1 pumilio RNA-binding family member 1 -0.0155877
SFSWAP splicing factor, suppressor of white-apricot family -0.0155654
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0155574
PARVB parvin, beta -0.0155451
SCAF11 SR-related CTD-associated factor 11 -0.0155289
TMEM245 transmembrane protein 245 -0.015511
XXYLT1 xyloside xylosyltransferase 1 -0.0155012
RPS7 ribosomal protein S7 -0.0154994
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0154922
CEMIP2 cell migration inducing hyaluronidase 2 -0.0154537
ATXN10 ataxin 10 -0.0154403
PFKP phosphofructokinase, platelet -0.015436
DCP1A decapping mRNA 1A -0.0154216
CDK19 cyclin-dependent kinase 19 -0.0154188
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.0153924
RAD21 RAD21 homolog (S. pombe) -0.0153914
SLC35E1 solute carrier family 35, member E1 -0.0153836
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0153737
MAP7 microtubule-associated protein 7 -0.0153453
AHCYL2 adenosylhomocysteinase-like 2 -0.0153449
MCM10 minichromosome maintenance complex component 10 -0.0153083
SSBP1 single-stranded DNA binding protein 1, mitochondrial -0.0152775
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0152581
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -0.0152491
FBXO28 F-box protein 28 -0.015225
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0151963
VAV1 vav 1 guanine nucleotide exchange factor -0.0151812
CTSD cathepsin D -0.0151682
SOD1 superoxide dismutase 1, soluble -0.0151602
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0151424
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -0.0151361
APTX aprataxin -0.0151175
ATAD2B ATPase family, AAA domain containing 2B -0.0150862
MCM9 minichromosome maintenance complex component 9 -0.0150715
PIF1 PIF1 5'-to-3' DNA helicase -0.0150677
VAC14 Vac14 homolog (S. cerevisiae) -0.0150572
RABEPK Rab9 effector protein with kelch motifs -0.0150402
EVL Enah/Vasp-like -0.015021
TOP1 topoisomerase (DNA) I -0.0150127
NR2F6 nuclear receptor subfamily 2, group F, member 6 -0.0149978
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0149859
COASY CoA synthase -0.0149744
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0149703
PTPRB protein tyrosine phosphatase, receptor type, B -0.014968
KHDC1 KH homology domain containing 1 -0.0149421
WTAP Wilms tumor 1 associated protein -0.0149196
HOOK3 hook microtubule-tethering protein 3 -0.0149154
YY1 YY1 transcription factor -0.0149024
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.0149008
UVRAG UV radiation resistance associated -0.0149006
LARP7 La ribonucleoprotein domain family, member 7 -0.0148748
WDR41 WD repeat domain 41 -0.0148603
PITX1 paired-like homeodomain 1 -0.014843
DYNC2I1 dynein 2 intermediate chain 1 -0.0148236
PCSK7 proprotein convertase subtilisin/kexin type 7 -0.0148229
IQGAP1 IQ motif containing GTPase activating protein 1 -0.014815
FER fer (fps/fes related) tyrosine kinase -0.0147983
CFAP251 cilia and flagella associated protein 251 -0.0147814
PDS5B PDS5 cohesin associated factor B -0.0147514
RUVBL1 RuvB-like AAA ATPase 1 -0.0147363
AGO1 argonaute RISC catalytic component 1 -0.0147211
XPO6 exportin 6 -0.0146907
ZDHHC17 zinc finger, DHHC-type containing 17 -0.0146777
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0146725
FKBP3 FK506 binding protein 3, 25kDa -0.0146539
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.0146389
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0146211
RBM10 RNA binding motif protein 10 -0.014575
TTF1 transcription termination factor, RNA polymerase I -0.014558