K562_SGI-1776 free base_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SGI-1776 free base 10nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_SGI-1776 free base_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0976101
HBG1 hemoglobin, gamma A 0.091081
TIMP1 TIMP metallopeptidase inhibitor 1 0.0834356
TLK1 tousled-like kinase 1 0.0637579
KIF13A kinesin family member 13A 0.0600596
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0598175
PRKCA protein kinase C, alpha 0.0594677
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.059397
MED15 mediator complex subunit 15 0.0590655
PRKCB protein kinase C, beta 0.0559001
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0552935
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0549826
RFWD3 ring finger and WD repeat domain 3 0.0544258
CALU calumenin 0.0538109
AGO2 argonaute RISC catalytic component 2 0.0527787
CCNY cyclin Y 0.0522778
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0508091
RNF24 ring finger protein 24 0.0505482
FAM178B family with sequence similarity 178, member B 0.0500091
NUP153 nucleoporin 153kDa 0.0490071
KDM4B lysine (K)-specific demethylase 4B 0.0478698
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0477162
KMT2A lysine (K)-specific methyltransferase 2A 0.0477046
THOC2 THO complex 2 0.0474989
CLASP2 cytoplasmic linker associated protein 2 0.0466742
NSD3 nuclear receptor binding SET domain protein 3 0.0462346
SEC31A SEC31 homolog A (S. cerevisiae) 0.0457564
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0455412
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0446627
ZDHHC17 zinc finger, DHHC-type containing 17 0.0446232
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0442686
SCAI suppressor of cancer cell invasion 0.0438242
ZMYM4 zinc finger, MYM-type 4 0.0435602
CHD9 chromodomain helicase DNA binding protein 9 0.0434795
GRB2 growth factor receptor-bound protein 2 0.0429864
SIK3 SIK family kinase 3 0.0429036
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0415271
ACTN4 actinin, alpha 4 0.0408783
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0408326
RPL37A ribosomal protein L37a 0.0408146
TLN1 talin 1 0.0401332
CDK6 cyclin-dependent kinase 6 0.0401146
MARCHF3 membrane associated ring-CH-type finger 3 0.0400241
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0396254
ZNF846 zinc finger protein 846 0.0396184
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0390399
ADAM17 ADAM metallopeptidase domain 17 0.0387048
RPS8 ribosomal protein S8 0.0386642
UBXN7 UBX domain protein 7 0.0386579
TAC4 tachykinin 4 (hemokinin) 0.0386532
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.038449
ERBIN erbb2 interacting protein 0.038281
KLHDC10 kelch domain containing 10 0.0382368
PDIA3 protein disulfide isomerase family A, member 3 0.0375364
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.0372792
PLEC plectin 0.0364194
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0362866
RAB1A RAB1A, member RAS oncogene family 0.0358051
KIF1B kinesin family member 1B 0.035693
USP20 ubiquitin specific peptidase 20 0.0353923
TTC17 tetratricopeptide repeat domain 17 0.0345118
DSCAM Down syndrome cell adhesion molecule 0.0345036
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.0343757
CAMKMT calmodulin-lysine N-methyltransferase 0.0340441
VIM vimentin 0.0339956
CDC73 cell division cycle 73 0.0339709
AKAP9 A kinase (PRKA) anchor protein 9 0.0336952
MAML2 mastermind-like 2 (Drosophila) 0.0334166
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0333235
DCAF7 DDB1 and CUL4 associated factor 7 0.0331478
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.0330175
FAM222B family with sequence similarity 222, member B 0.0330116
DLG1 discs, large homolog 1 (Drosophila) 0.0328445
LTBP1 latent transforming growth factor beta binding protein 1 0.0327515
HDGF hepatoma-derived growth factor 0.0327453
CCDC18 coiled-coil domain containing 18 0.0326364
PGPEP1 pyroglutamyl-peptidase I 0.0325921
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0323155
TBC1D5 TBC1 domain family, member 5 0.0320019
GPC5 glypican 5 0.0319582
COP1 COP1 E3 ubiquitin ligase 0.031903
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.0317197
STRN striatin, calmodulin binding protein 0.0315067
TMEM120B transmembrane protein 120B 0.0314069
PCNT pericentrin 0.0312431
ZNF431 zinc finger protein 431 0.0311416
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.0308874
ADIPOR2 adiponectin receptor 2 0.0306473
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0305782
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0304294
ACYP2 acylphosphatase 2, muscle type 0.0303699
SCG3 secretogranin III 0.0303597
MAP2K1 mitogen-activated protein kinase kinase 1 0.0303257
HIPK2 homeodomain interacting protein kinase 2 0.0302483
DMD dystrophin 0.0301184
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0299338
SRPK2 SRSF protein kinase 2 0.0298619
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0298212
CD44 CD44 molecule (Indian blood group) 0.0295559
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.0293438
RPL32 ribosomal protein L32 0.0292786
CALR calreticulin 0.0292292
HELZ helicase with zinc finger 0.0291404
SPRED2 sprouty-related, EVH1 domain containing 2 0.0291096
SCAF11 SR-related CTD-associated factor 11 0.0290981
GOLGB1 golgin B1 0.0290696
CDC14A cell division cycle 14A 0.0289512
RBMX RNA binding motif protein, X-linked 0.0286836
S100PBP S100P binding protein 0.0286114
BCLAF1 BCL2-associated transcription factor 1 0.0285516
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0285304
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.0284266
LNPK lunapark, ER junction formation factor 0.0284119
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0283537
COMT catechol-O-methyltransferase 0.0282368
TSPAN5 tetraspanin 5 0.0281929
GDF15 growth differentiation factor 15 0.0280829
MYO1D myosin ID 0.0280565
RSRP1 arginine/serine-rich protein 1 0.0279973
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0279848
ZHX3 zinc fingers and homeoboxes 3 0.0279659
OXNAD1 oxidoreductase NAD-binding domain containing 1 0.0279035
FAM120B family with sequence similarity 120B 0.0278333
TSPAN14 tetraspanin 14 0.0277375
TM9SF4 transmembrane 9 superfamily protein member 4 0.0276342
MICU1 mitochondrial calcium uptake 1 0.0274616
RAB22A RAB22A, member RAS oncogene family 0.0273223
DYM dymeclin 0.0273155
USP15 ubiquitin specific peptidase 15 0.0272551
ORC3 origin recognition complex, subunit 3 0.0271905
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0271855
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0271489
BICD2 bicaudal D homolog 2 (Drosophila) 0.0270217
ENSA endosulfine alpha 0.0270203
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.026967
CDC45 cell division cycle 45 0.0268224
RNF213 ring finger protein 213 0.0267772
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0266797
CNTNAP2 contactin associated protein-like 2 0.0266554
MCM3AP minichromosome maintenance complex component 3 associated protein 0.0265602
BTNL9 butyrophilin-like 9 0.0263839
KYAT1 kynurenine aminotransferase 1 0.0262656
GATA2 GATA binding protein 2 0.026169
CA8 carbonic anhydrase VIII 0.0261567
RPS4X ribosomal protein S4, X-linked 0.0261399
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0261173
LIMS1 LIM and senescent cell antigen-like domains 1 0.0261085
CELF1 CUGBP, Elav-like family member 1 0.0260926
MCM8 minichromosome maintenance complex component 8 0.0260656
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 0.0260444
LOC112694756 uncharaterized LOC112694756 0.0260401
NF1 neurofibromin 1 0.02602
STX12 syntaxin 12 0.0259314
ATM ATM serine/threonine kinase 0.0257161
SLC35F5 solute carrier family 35, member F5 0.0256107
UNC13D unc-13 homolog D (C. elegans) 0.0255755
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 0.0255508
CEP192 centrosomal protein 192kDa 0.0254441
ZNF791 zinc finger protein 791 0.0252294
SPIRE1 spire-type actin nucleation factor 1 0.0251819
ZBTB38 zinc finger and BTB domain containing 38 0.0251732
ITSN1 intersectin 1 (SH3 domain protein) 0.0251601
SREBF2 sterol regulatory element binding transcription factor 2 0.0250468
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.0250362
EPS15 epidermal growth factor receptor pathway substrate 15 0.0249808
CHD7 chromodomain helicase DNA binding protein 7 0.024875
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.0248171
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0247969
TNIK TRAF2 and NCK interacting kinase 0.0247809
KIAA0319L KIAA0319-like 0.024762
TLE5 TLE family member 5, transcriptional modulator 0.0247358
CAVIN1 caveolae associated protein 1 0.0246696
MUSK muscle, skeletal, receptor tyrosine kinase 0.0245642
ST7L suppression of tumorigenicity 7 like 0.0244908
ANGPTL4 angiopoietin-like 4 0.0244898
NBAS neuroblastoma amplified sequence 0.0244881
ETNK1 ethanolamine kinase 1 0.0243876
SEPTIN11 septin 11 0.02438
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.024361
LONP2 lon peptidase 2, peroxisomal 0.024346
ZYG11B zyg-11 family member B, cell cycle regulator 0.0243102
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0242618
TUBA1B tubulin, alpha 1b 0.0241922
TIMM23B translocase of inner mitochondrial membrane 23 homolog B (yeast) 0.0241531
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0241506
TBL1X transducin (beta)-like 1X-linked 0.0241358
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.024051
STAT5B signal transducer and activator of transcription 5B 0.0240271
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.0239365
FBXL4 F-box and leucine-rich repeat protein 4 0.023934
RILPL1 Rab interacting lysosomal protein-like 1 0.0238221
RPS29 ribosomal protein S29 0.0238127
DOT1L DOT1-like histone H3K79 methyltransferase 0.0237687
AARS1 alanyl-tRNA synthetase 1 0.0237536
BSG basigin (Ok blood group) 0.0237492
POU2F1 POU class 2 homeobox 1 0.0236513
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0236344
AKAP12 A kinase (PRKA) anchor protein 12 0.0236201
MCAM melanoma cell adhesion molecule 0.0236168
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0235207
TXNL4A thioredoxin-like 4A 0.0234899
KLHDC4 kelch domain containing 4 0.023486
MYH10 myosin, heavy chain 10, non-muscle 0.0233702
OSBP oxysterol binding protein 0.0233626
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.0233194
BICD1 bicaudal D homolog 1 (Drosophila) 0.0231219
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.0230737
ANAPC16 anaphase promoting complex subunit 16 0.0230414
FNDC3A fibronectin type III domain containing 3A 0.0230027
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 0.0229745
ZBTB43 zinc finger and BTB domain containing 43 0.0229096
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0228485
RACK1 receptor for activated C kinase 1 0.0228477
GDE1 glycerophosphodiester phosphodiesterase 1 0.0228279
TMSB10 thymosin beta 10 0.0227854
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.0227732
LEPROT leptin receptor overlapping transcript 0.022738
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0227373
ALKBH5 AlkB family member 5, RNA demethylase 0.0226461
COMMD1 copper metabolism (Murr1) domain containing 1 0.0226153
UBE3A ubiquitin protein ligase E3A 0.0226041
ZBTB7A zinc finger and BTB domain containing 7A 0.0225738
TRAP1 TNF receptor-associated protein 1 0.0225368
PSPH phosphoserine phosphatase 0.0224913
CLEC16A C-type lectin domain family 16, member A 0.0224742
OIP5 Opa interacting protein 5 0.0224471
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.0224092
LTN1 listerin E3 ubiquitin protein ligase 1 0.0223866
ACTN1 actinin, alpha 1 0.0223668
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0223384
RTN4 reticulon 4 0.0223378
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.022253
SECISBP2L SECIS binding protein 2-like 0.0222486
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0221751
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0221628
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.02215
BCAP29 B-cell receptor-associated protein 29 0.0221457
MAP2K5 mitogen-activated protein kinase kinase 5 0.0220437
PCBP2 poly(rC) binding protein 2 0.0220034
TMCO1 transmembrane and coiled-coil domains 1 0.0219848
STON2 stonin 2 0.0219807
ATF5 activating transcription factor 5 0.0219133
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0218952
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.0216756
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.0216703
RAI14 retinoic acid induced 14 0.0216702
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0216238
ZNF407 zinc finger protein 407 0.0215964
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.021581
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0215782
TPX2 TPX2, microtubule-associated 0.0215095
SFTPA2 surfactant protein A2 0.0215091
STAU1 staufen double-stranded RNA binding protein 1 0.021385
RPS9 ribosomal protein S9 0.0213833
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0213433
SRSF4 serine/arginine-rich splicing factor 4 0.0212298
FAM193A family with sequence similarity 193, member A 0.0212221
GMCL1 germ cell-less, spermatogenesis associated 1 0.0212195
RCC2 regulator of chromosome condensation 2 0.0212058
SELENOF selenoprotein F 0.0211839
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 0.0211692
KAZN kazrin, periplakin interacting protein 0.0211468
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.0211448
LAMP1 lysosomal-associated membrane protein 1 0.0210862
BRD4 bromodomain containing 4 0.0210831
ADAM10 ADAM metallopeptidase domain 10 0.0210484
TYK2 tyrosine kinase 2 0.020998
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0209382
C6ORF89 chromosome 6 open reading frame 89 0.0208531
LCORL ligand dependent nuclear receptor corepressor-like 0.0208257
CTSD cathepsin D 0.0207824
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.020764
LY6E lymphocyte antigen 6 complex, locus E 0.0207067
CEP95 centrosomal protein 95kDa 0.0206966
E2F3 E2F transcription factor 3 0.0206847
EPM2AIP1 EPM2A (laforin) interacting protein 1 0.0206105
SMC3 structural maintenance of chromosomes 3 0.0206041
FCHSD2 FCH and double SH3 domains 2 0.0205806
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0205785
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.0205449
PHKB phosphorylase kinase, beta 0.0205341
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.0205192
SRGN serglycin 0.0205114
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0204995
PHGDH phosphoglycerate dehydrogenase 0.0204863
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0204299
GON4L gon-4-like (C. elegans) 0.020403
CCDC138 coiled-coil domain containing 138 0.020379
ADARB1 adenosine deaminase, RNA-specific, B1 0.0203755
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.0203603
NKTR natural killer cell triggering receptor 0.0203535
PHAX phosphorylated adaptor for RNA export 0.020349
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.020347
WSB1 WD repeat and SOCS box containing 1 0.020329
BBS4 Bardet-Biedl syndrome 4 0.0203119
SRFBP1 serum response factor binding protein 1 0.0202782
RPS17 ribosomal protein S17 0.0202274
RHAG Rh-associated glycoprotein 0.0202244
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0201961
RB1CC1 RB1-inducible coiled-coil 1 0.0201842
GAPVD1 GTPase activating protein and VPS9 domains 1 0.0201169
SLC35E2B solute carrier family 35, member E2B 0.0201036
RPS2 ribosomal protein S2 0.0200659
NRXN3 neurexin 3 0.0200001
THAP12 THAP domain containing 12 0.0199929
ANKRD17 ankyrin repeat domain 17 0.0199732
IQGAP1 IQ motif containing GTPase activating protein 1 0.0199529
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0199362
ZNF800 zinc finger protein 800 0.0198537
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.0198488
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 0.0198231
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.0198001
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0197999
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0197794
WT1 Wilms tumor 1 0.0197767
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0197719
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0197583
UBXN4 UBX domain protein 4 0.0197504
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0197197
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.0196596
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0196219
TTC7A tetratricopeptide repeat domain 7A 0.0195645
MED24 mediator complex subunit 24 0.0194117
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0193819
DCHS2 dachsous cadherin-related 2 0.019381
SRRM1 serine/arginine repetitive matrix 1 0.0193715
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 0.0193423
NUMA1 nuclear mitotic apparatus protein 1 0.0193028
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0192862
GLMN glomulin, FKBP associated protein 0.0192856
CTSB cathepsin B 0.0192782
BAG1 BCL2-associated athanogene 0.0192738
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0192508
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0192451
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.0192374
ADGRB3 adhesion G protein-coupled receptor B3 0.0192195
LDHA lactate dehydrogenase A 0.019209
ZNF714 zinc finger protein 714 0.0192089
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.0192058
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.0191989
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0191987
ADNP2 ADNP homeobox 2 0.0191894
NSUN4 NOP2/Sun domain family, member 4 0.019147
PRDM2 PR domain containing 2, with ZNF domain 0.0191122
CENPO centromere protein O 0.0190779
BIRC5 baculoviral IAP repeat containing 5 0.0190763
SEC24D SEC24 family member D 0.0190497
DLG5 discs, large homolog 5 (Drosophila) 0.01901
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0188982
PDIA6 protein disulfide isomerase family A, member 6 0.0188918
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.0188757
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.0188641
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 0.01886
TJP2 tight junction protein 2 0.0188402
DROSHA drosha, ribonuclease type III 0.0188187
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.018775
C17ORF99 chromosome 17 open reading frame 99 0.0187382
FAM91A1 family with sequence similarity 91, member A1 0.0187322
KRT8 keratin 8, type II 0.0186832
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.0186773
ENKUR enkurin, TRPC channel interacting protein 0.0186688
STX17 syntaxin 17 0.0186566
EPHX2 epoxide hydrolase 2, cytoplasmic 0.0186408
ZNF236 zinc finger protein 236 0.0186379
MXI1 MAX interactor 1, dimerization protein 0.01861
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.018609
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.0185751
ATAD2 ATPase family, AAA domain containing 2 0.0185506
SLC38A6 solute carrier family 38, member 6 0.0185192
R3HDM2 R3H domain containing 2 0.0185175
ATG7 autophagy related 7 0.0185133
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0184981
DDIT4 DNA-damage-inducible transcript 4 0.018496
SNX9 sorting nexin 9 0.0184859
ZC3H6 zinc finger CCCH-type containing 6 0.018485
GRB10 growth factor receptor-bound protein 10 0.0184347
MARF1 meiosis regulator and mRNA stability factor 1 0.0184272
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.018381
NSD2 nuclear receptor binding SET domain protein 2 0.0183792
RPL7L1 ribosomal protein L7-like 1 0.0183576
TACC1 transforming, acidic coiled-coil containing protein 1 0.0183392
DEPDC5 DEP domain containing 5 0.01832
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0183199
UBE2K ubiquitin-conjugating enzyme E2K 0.0183126
DCTN2 dynactin 2 (p50) 0.0182958
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.0182945
PDIA5 protein disulfide isomerase family A, member 5 0.0182797
DNM2 dynamin 2 0.0182703
RPS12 ribosomal protein S12 0.0182659
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.0182411
EXOC6 exocyst complex component 6 0.018222
RPL27 ribosomal protein L27 0.0181576
KIAA0586 KIAA0586 0.0181562
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.0181521
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.0181115
CANX calnexin 0.0180565
WARS1 tryptophanyl-tRNA synthetase 1 0.0180508
PPCDC phosphopantothenoylcysteine decarboxylase 0.0180451
RPL3 ribosomal protein L3 0.0180401
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0179814
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0179798
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0179359
SEPTIN7 septin 7 0.017933
THRAP3 thyroid hormone receptor associated protein 3 0.0178848
IL6ST interleukin 6 signal transducer 0.0178482
TMEM108 transmembrane protein 108 0.0178113
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.0178004
NFE2L2 nuclear factor, erythroid 2-like 2 0.0177971
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0177475
PKP4 plakophilin 4 0.0177368
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0176913
CUEDC1 CUE domain containing 1 0.0176846
MSI2 musashi RNA-binding protein 2 0.0176635
TET2 tet methylcytosine dioxygenase 2 0.0176434
CTR9 CTR9, Paf1/RNA polymerase II complex component 0.0176217
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0175929
TP63 tumor protein p63 0.0175749
CCDC88A coiled-coil domain containing 88A 0.0175514
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0175419
AGK acylglycerol kinase 0.0175184
ELOVL6 ELOVL fatty acid elongase 6 0.0175116
LMAN1 lectin, mannose-binding, 1 0.0174697
ATRN attractin 0.0174651
ZNF609 zinc finger protein 609 0.0174357
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0174244
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.017397
RNF170 ring finger protein 170 0.0173967
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0173881
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.0173761
STX3 syntaxin 3 0.0173685
HDAC4 histone deacetylase 4 0.017348
LPXN leupaxin 0.01734
RPS20 ribosomal protein S20 0.0173394
USP3 ubiquitin specific peptidase 3 0.0173291
RNF217 ring finger protein 217 0.0173226
SH2B3 SH2B adaptor protein 3 0.0173197
LUC7L LUC7-like (S. cerevisiae) 0.01731
ARHGAP6 Rho GTPase activating protein 6 0.0173009
ISYNA1 inositol-3-phosphate synthase 1 0.0172826
CD59 CD59 molecule, complement regulatory protein 0.0172802
ICE1 interactor of little elongation complex ELL subunit 1 0.0172776
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.0172753
BLZF1 basic leucine zipper nuclear factor 1 0.0172539
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.0172287
BPTF bromodomain PHD finger transcription factor 0.0172242
CLTCL1 clathrin, heavy chain-like 1 0.0172072
CNST consortin, connexin sorting protein 0.0171917
RPS10 ribosomal protein S10 0.0171792
TULP4 tubby like protein 4 0.0171631
PFN1 profilin 1 0.0171393
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.0171211
PCGF5 polycomb group ring finger 5 0.0171194
LRRC57 leucine rich repeat containing 57 0.0171021
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0170971
PABIR2 PABIR family member 2 0.0170427
RTN3 reticulon 3 0.0170371
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0169564
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0169513
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.0168994
OARD1 O-acyl-ADP-ribose deacylase 1 0.0168914
ADGRE5 adhesion G protein-coupled receptor E5 0.0168821
H2AZ2 H2A.Z variant histone 2 0.01688
TUT4 terminal uridylyl transferase 4 0.0168682
CLIC4 chloride intracellular channel 4 0.0168145
SMIM44 small integral membrane protein 44 0.0168086
SERTAD2 SERTA domain containing 2 0.0167793
SGO2 shugoshin 2 0.016753
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 0.0167323
UBC ubiquitin C 0.0166934
GOLT1A golgi transport 1A 0.0166819
CDK13 cyclin-dependent kinase 13 0.0166598
SNX14 sorting nexin 14 0.0166076
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.0165813
ATXN3 ataxin 3 0.0165599
DHCR7 7-dehydrocholesterol reductase 0.0165498
PDLIM7 PDZ and LIM domain 7 (enigma) 0.0165454
HERPUD2 HERPUD family member 2 0.016541
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0165214
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.0165201
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0165127
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.0165069
TMOD1 tropomodulin 1 0.0165052
DAND5 DAN domain family member 5, BMP antagonist 0.0164848
RPL13A ribosomal protein L13a 0.016414
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0163798
SACK1A scaffolding CK1 anchoring protein A 0.0163742
ASXL1 additional sex combs like transcriptional regulator 1 0.0163642
ERMP1 endoplasmic reticulum metallopeptidase 1 0.0163587
IGBP1 immunoglobulin (CD79A) binding protein 1 0.0162538
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 0.0162499
SUMF1 sulfatase modifying factor 1 0.0161964
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0161662
KEL Kell blood group, metallo-endopeptidase 0.0161638
PTK2B protein tyrosine kinase 2 beta 0.0161452
SWI5 SWI5 recombination repair homolog (yeast) 0.0161436
RAB5A RAB5A, member RAS oncogene family 0.0161346
UBALD1 UBA-like domain containing 1 0.0160998
PRKCI protein kinase C, iota 0.0160914
MTF2 metal response element binding transcription factor 2 0.0160671
SAMD4A sterile alpha motif domain containing 4A 0.0160166

decreased expression

Symbol Name Standardized Value
PRRC2C proline-rich coiled-coil 2C -0.0838346
PICALM phosphatidylinositol binding clathrin assembly protein -0.0706585
GSE1 Gse1 coiled-coil protein -0.0619498
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0595016
CALN1 calneuron 1 -0.0561809
RPL15 ribosomal protein L15 -0.0560911
DIAPH1 diaphanous-related formin 1 -0.0547363
LMBR1 limb development membrane protein 1 -0.0543033
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0534661
MAP4 microtubule-associated protein 4 -0.0532754
ARL15 ADP-ribosylation factor-like 15 -0.0514051
RABGAP1L RAB GTPase activating protein 1-like -0.0510603
SEC11A SEC11 homolog A (S. cerevisiae) -0.0506327
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0494026
LDLR low density lipoprotein receptor -0.0480471
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0477798
PHACTR4 phosphatase and actin regulator 4 -0.0476198
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0450271
COG5 component of oligomeric golgi complex 5 -0.0438595
KHSRP KH-type splicing regulatory protein -0.043377
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0424591
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.042299
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.042236
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0419852
IARS1 isoleucyl-tRNA synthetase 1 -0.0416139
PUM1 pumilio RNA-binding family member 1 -0.0415217
WDR33 WD repeat domain 33 -0.0408081
MBNL1 muscleblind-like splicing regulator 1 -0.0406156
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0402258
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0401492
CENPE centromere protein E, 312kDa -0.0401405
RHOBTB3 Rho-related BTB domain containing 3 -0.0401313
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0391528
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0386396
SPIDR scaffolding protein involved in DNA repair -0.0381914
TOP1 topoisomerase (DNA) I -0.0378387
RC3H1 ring finger and CCCH-type domains 1 -0.0378089
MAPK1 mitogen-activated protein kinase 1 -0.0377659
DMXL1 Dmx-like 1 -0.0377339
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.0372127
CNKSR3 CNKSR family member 3 -0.0371953
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0371843
TPR translocated promoter region, nuclear basket protein -0.036718
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0365672
FAF1 Fas (TNFRSF6) associated factor 1 -0.0365361
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0362207
PUS7 pseudouridylate synthase 7 (putative) -0.0357797
PITRM1 pitrilysin metallopeptidase 1 -0.0356623
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0355298
SETD5 SET domain containing 5 -0.0355004
SETD2 SET domain containing 2 -0.0354715
TENT2 terminal nucleotidyltransferase 2 -0.0352857
AK1 adenylate kinase 1 -0.0352841
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0352004
NOL4L nucleolar protein 4-like -0.0349432
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.034189
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0341694
SMYD3 SET and MYND domain containing 3 -0.0339674
RBM39 RNA binding motif protein 39 -0.0336245
VMP1 vacuole membrane protein 1 -0.0336242
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0336228
DCAF10 DDB1 and CUL4 associated factor 10 -0.0335608
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0334634
ANKRD11 ankyrin repeat domain 11 -0.0331039
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0327792
MPHOSPH9 M-phase phosphoprotein 9 -0.0326545
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0326182
SSH2 slingshot protein phosphatase 2 -0.0325051
PDS5A PDS5 cohesin associated factor A -0.0322934
CERT1 ceramide transporter 1 -0.0322467
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0322443
TUBB tubulin, beta class I -0.0321453
PTPRA protein tyrosine phosphatase, receptor type, A -0.0320052
RAB7A RAB7A, member RAS oncogene family -0.0319971
PTH2R parathyroid hormone 2 receptor -0.0318166
FBXL13 F-box and leucine-rich repeat protein 13 -0.0316791
TMEM131L transmembrane 131 like -0.0316542
GAB2 GRB2-associated binding protein 2 -0.0312721
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0310671
SUCO SUN domain containing ossification factor -0.0310229
KAT6A K(lysine) acetyltransferase 6A -0.0308454
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.030776
ARHGAP18 Rho GTPase activating protein 18 -0.0306996
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0306718
USP32 ubiquitin specific peptidase 32 -0.0302939
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0301842
NEK1 NIMA-related kinase 1 -0.0301432
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0299248
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0298798
RAB28 RAB28, member RAS oncogene family -0.0298766
SCFD2 sec1 family domain containing 2 -0.0297565
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0297511
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0295603
WAC WW domain containing adaptor with coiled-coil -0.0293822
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0292592
MEIS2 Meis homeobox 2 -0.0292424
FOXK2 forkhead box K2 -0.0290432
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0289831
ZNF83 zinc finger protein 83 -0.0288904
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0286023
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 -0.0285902
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0285618
KIF20B kinesin family member 20B -0.0284154
SLC38A1 solute carrier family 38, member 1 -0.0283122
ZNF106 zinc finger protein 106 -0.0281311
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0281001
FER fer (fps/fes related) tyrosine kinase -0.0280677
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0280528
SLMAP sarcolemma associated protein -0.0277387
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 -0.0276317
MTX2 metaxin 2 -0.0276224
RNF115 ring finger protein 115 -0.0275494
URI1 URI1, prefoldin-like chaperone -0.0274817
TNPO2 transportin 2 -0.027292
CREB1 cAMP responsive element binding protein 1 -0.0272553
STRN3 striatin, calmodulin binding protein 3 -0.0269896
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.0268695
KMT2E lysine (K)-specific methyltransferase 2E -0.0268135
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0267618
PARN poly(A)-specific ribonuclease -0.026665
SKIC3 SKI3 subunit of superkiller complex -0.0266571
UBE3C ubiquitin protein ligase E3C -0.0265831
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.0265476
TNPO1 transportin 1 -0.0264076
CCAR1 cell division cycle and apoptosis regulator 1 -0.0262648
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0262537
MBNL2 muscleblind-like splicing regulator 2 -0.0261644
ABHD5 abhydrolase domain containing 5 -0.0261106
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0260811
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0258741
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0258487
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -0.025737
AFDN afadin, adherens junction formation factor -0.0256611
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0255686
RORA RAR-related orphan receptor A -0.0255583
GSK3B glycogen synthase kinase 3 beta -0.0254374
TOX4 TOX high mobility group box family member 4 -0.0254328
NACA nascent polypeptide-associated complex alpha subunit -0.0254178
ASPH aspartate beta-hydroxylase -0.0253955
SPPL3 signal peptide peptidase like 3 -0.0253714
RBM15 RNA binding motif protein 15 -0.0251505
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.025139
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -0.0249904
ACBD6 acyl-CoA binding domain containing 6 -0.0249676
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0249666
AGO1 argonaute RISC catalytic component 1 -0.0249531
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0249523
TEX2 testis expressed 2 -0.0249141
VCP valosin containing protein -0.0248137
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta -0.0248063
ESYT2 extended synaptotagmin-like protein 2 -0.0247739
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -0.0247558
RAB6A RAB6A, member RAS oncogene family -0.0247436
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.0246425
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0246259
RPL22 ribosomal protein L22 -0.0246219
ENO1 enolase 1, (alpha) -0.0245098
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0244994
GIPR gastric inhibitory polypeptide receptor -0.0244555
RBM28 RNA binding motif protein 28 -0.0242049
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0241918
SERBP1 SERPINE1 mRNA binding protein 1 -0.0241382
CCDC91 coiled-coil domain containing 91 -0.0239185
PARD3B par-3 family cell polarity regulator beta -0.0238727
TRAPPC10 trafficking protein particle complex 10 -0.0237703
R3HDM1 R3H domain containing 1 -0.0237047
MVD mevalonate (diphospho) decarboxylase -0.0236104
MED13L mediator complex subunit 13-like -0.0234824
RFX7 regulatory factor X, 7 -0.0234647
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0234603
ZFPM2 zinc finger protein, FOG family member 2 -0.0234234
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0234106
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0233409
MINDY3 MINDY lysine 48 deubiquitinase 3 -0.0233197
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -0.0232652
CUX1 cut-like homeobox 1 -0.0232327
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.023194
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.0231802
ZC3H13 zinc finger CCCH-type containing 13 -0.0230828
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0230617
FHIT fragile histidine triad -0.0229635
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0229225
ELOVL5 ELOVL fatty acid elongase 5 -0.0228799
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0228747
LARP4B La ribonucleoprotein domain family, member 4B -0.0228726
HEATR1 HEAT repeat containing 1 -0.0227729
TRAPPC12 trafficking protein particle complex 12 -0.0227708
CEMIP2 cell migration inducing hyaluronidase 2 -0.0223285
NFX1 nuclear transcription factor, X-box binding 1 -0.0223244
FOXK1 forkhead box K1 -0.0222504
KDM3B lysine (K)-specific demethylase 3B -0.0222374
JARID2 jumonji, AT rich interactive domain 2 -0.022183
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0219598
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0219179
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0218598
HOMER1 homer scaffolding protein 1 -0.0217665
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.021766
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0217526
BMP2K BMP2 inducible kinase -0.0216422
MRPL13 mitochondrial ribosomal protein L13 -0.0216229
KLHL8 kelch-like family member 8 -0.0215286
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0214663
ANK1 ankyrin 1, erythrocytic -0.0214281
MTIF2 mitochondrial translational initiation factor 2 -0.0213618
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.0213618
SMAP2 small ArfGAP2 -0.0213476
TCF3 transcription factor 3 -0.0212952
IPO7 importin 7 -0.0211438
TRAK1 trafficking protein, kinesin binding 1 -0.0211015
NLK nemo-like kinase -0.021014
MGA MGA, MAX dimerization protein -0.0209935
CENPP centromere protein P -0.0209072
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -0.0208545
HBG2 hemoglobin, gamma G -0.0208312
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0207828
ZMYND8 zinc finger, MYND-type containing 8 -0.0207784
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0207682
TNRC18 trinucleotide repeat containing 18 -0.0207323
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.0206323
PRAME preferentially expressed antigen in melanoma -0.020629
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0206167
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0206151
TCAF1 TRPM8 channel-associated factor 1 -0.020615
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0205034
RUVBL2 RuvB-like AAA ATPase 2 -0.0204704
RUNX1 runt-related transcription factor 1 -0.0204316
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0203126
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0202541
FBXO42 F-box protein 42 -0.0202257
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.0201956
ABHD2 abhydrolase domain containing 2 -0.0201638
RSBN1L round spermatid basic protein 1-like -0.02015
MTMR3 myotubularin related protein 3 -0.0201418
CDK17 cyclin-dependent kinase 17 -0.0200989
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0200956
SRSF3 serine/arginine-rich splicing factor 3 -0.020001
CYCS cytochrome c, somatic -0.0199889
DCAF6 DDB1 and CUL4 associated factor 6 -0.0199784
CYRIB CYFIP related Rac1 interactor B -0.0199665
BRWD1 bromodomain and WD repeat domain containing 1 -0.0199438
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0199216
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -0.01991
CEP350 centrosomal protein 350kDa -0.0198664
ICE2 interactor of little elongation complex ELL subunit 2 -0.0198554
MSN moesin -0.0198291
SENP7 SUMO1/sentrin specific peptidase 7 -0.0197191
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0197144
GK5 glycerol kinase 5 (putative) -0.0196962
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0196835
HLTF helicase-like transcription factor -0.019681
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0196335
LBR lamin B receptor -0.0195817
CHKA choline kinase alpha -0.0195581
RPL38 ribosomal protein L38 -0.0195508
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0195389
CASP8AP2 caspase 8 associated protein 2 -0.0194451
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -0.0193822
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0193212
USP49 ubiquitin specific peptidase 49 -0.0193031
KIF21A kinesin family member 21A -0.0192389
EVI5 ecotropic viral integration site 5 -0.0191821
TXLNG taxilin gamma -0.0191762
CAPN1 calpain 1, (mu/I) large subunit -0.0191481
ITSN2 intersectin 2 -0.0191156
GPBP1L1 GC-rich promoter binding protein 1-like 1 -0.0190963
ADGRV1 adhesion G protein-coupled receptor V1 -0.0190898
NOP58 NOP58 ribonucleoprotein -0.0190596
FASTKD1 FAST kinase domains 1 -0.0190491
KARS1 lysyl-tRNA synthetase 1 -0.0189838
CSNK1G2 casein kinase 1, gamma 2 -0.0189793
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0188848
GCLM glutamate-cysteine ligase, modifier subunit -0.0188472
KCTD20 potassium channel tetramerization domain containing 20 -0.018833
FBXL17 F-box and leucine-rich repeat protein 17 -0.0188134
LIMA1 LIM domain and actin binding 1 -0.0187999
PAAF1 proteasomal ATPase-associated factor 1 -0.0187963
RBM10 RNA binding motif protein 10 -0.0187756
SPPL2A signal peptide peptidase like 2A -0.0187681
TFCP2 transcription factor CP2 -0.0187465
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0187241
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -0.01871
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0186988
BCR breakpoint cluster region -0.0186383
NRDC nardilysin convertase -0.0186303
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0185697
STAU2 staufen double-stranded RNA binding protein 2 -0.018568
WAPL WAPL cohesin release factor -0.0185398
DBT dihydrolipoamide branched chain transacylase E2 -0.0185202
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0185173
RAB8B RAB8B, member RAS oncogene family -0.0184921
DLK1 delta-like 1 homolog (Drosophila) -0.0184517
WDR44 WD repeat domain 44 -0.0184232
SMC5 structural maintenance of chromosomes 5 -0.0183849
SKP1 S-phase kinase-associated protein 1 -0.0183588
PTBP3 polypyrimidine tract binding protein 3 -0.0183522
PGRMC2 progesterone receptor membrane component 2 -0.0183435
KMT2D lysine (K)-specific methyltransferase 2D -0.0183374
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.0183325
SMC1A structural maintenance of chromosomes 1A -0.0182928
SHLD2 shieldin complex subunit 2 -0.018236
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0182192
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0181502
AHDC1 AT hook, DNA binding motif, containing 1 -0.0181311
ITCH itchy E3 ubiquitin protein ligase -0.0181025
PTGFRN prostaglandin F2 receptor inhibitor -0.0180871
PIGU phosphatidylinositol glycan anchor biosynthesis, class U -0.0180504
NLN neurolysin (metallopeptidase M3 family) -0.0180477
KCMF1 potassium channel modulatory factor 1 -0.0180302
PTK2 protein tyrosine kinase 2 -0.0180079
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0179988
SCYL2 SCY1-like 2 (S. cerevisiae) -0.0179359
SAFB scaffold attachment factor B -0.0178876
SPOP speckle-type POZ protein -0.0178641
CPEB1 cytoplasmic polyadenylation element binding protein 1 -0.0178547
CEP57 centrosomal protein 57kDa -0.0177999
RPS19 ribosomal protein S19 -0.0177848
ARHGAP35 Rho GTPase activating protein 35 -0.017773
GPBP1 GC-rich promoter binding protein 1 -0.0177579
YARS1 tyrosyl-tRNA synthetase 1 -0.0177487
ATXN7 ataxin 7 -0.0177125
DHRS7B dehydrogenase/reductase (SDR family) member 7B -0.017691
TPI1 triosephosphate isomerase 1 -0.0176863
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0176822
TCF12 transcription factor 12 -0.0175981
SYAP1 synapse associated protein 1 -0.017586
PDLIM5 PDZ and LIM domain 5 -0.01757
PRKCQ protein kinase C, theta -0.0175513
RPS5 ribosomal protein S5 -0.0175123
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -0.0175076
ZNF292 zinc finger protein 292 -0.0174975
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.0174689
POU6F2 POU class 6 homeobox 2 -0.0174188
ANKRD28 ankyrin repeat domain 28 -0.0174152
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -0.0173895
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0173447
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -0.0173175
KIF18B kinesin family member 18B -0.0173122
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -0.0172076
NUP98 nucleoporin 98kDa -0.0172012
SLC25A42 solute carrier family 25, member 42 -0.0171867
LONRF3 LON peptidase N-terminal domain and ring finger 3 -0.0171665
CRTC3 CREB regulated transcription coactivator 3 -0.0171449
KIF14 kinesin family member 14 -0.0171025
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -0.0170973
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.0170969
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0170856
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -0.0170795
SLC10A7 solute carrier family 10, member 7 -0.0170737
DGKZ diacylglycerol kinase, zeta -0.0170499
UBAC1 UBA domain containing 1 -0.0170315
KATNBL1 katanin p80 subunit B-like 1 -0.0169993
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0169946
NIPAL3 NIPA-like domain containing 3 -0.0169423
VCL vinculin -0.0169212
AIG1 androgen-induced 1 -0.0168589
DBF4B DBF4 zinc finger B -0.0168334
POLK polymerase (DNA directed) kappa -0.0168261
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0168239
GLG1 golgi glycoprotein 1 -0.0167987
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0167561
DBF4 DBF4 zinc finger -0.0167332
IWS1 IWS1 homolog (S. cerevisiae) -0.0167263
GFOD2 glucose-fructose oxidoreductase domain containing 2 -0.0166807
DENND4A DENN/MADD domain containing 4A -0.0166725
UBXN2A UBX domain protein 2A -0.0166616
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.0166418
SPTA1 spectrin, alpha, erythrocytic 1 -0.0166398
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0166085
RAP1A RAP1A, member of RAS oncogene family -0.0165713
TOP3A topoisomerase (DNA) III alpha -0.0165601
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0165531
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0165444
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -0.0165282
MYO9B myosin IXB -0.0165014
CCDC137 coiled-coil domain containing 137 -0.0164878
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0164856
INTS6L integrator complex subunit 6 like -0.0164619
ATG5 autophagy related 5 -0.0164548
KDM4A lysine (K)-specific demethylase 4A -0.016418
RANBP10 RAN binding protein 10 -0.0164037
SLK STE20-like kinase -0.0164027
CORO1B coronin, actin binding protein, 1B -0.0163953
UTRN utrophin -0.0163883
MARCHF6 membrane associated ring-CH-type finger 6 -0.0163492
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0163037
BZW2 basic leucine zipper and W2 domains 2 -0.0162791
NCOA1 nuclear receptor coactivator 1 -0.0162647
CSDE1 cold shock domain containing E1, RNA-binding -0.0162436
CREG1 cellular repressor of E1A-stimulated genes 1 -0.0162429
XPO5 exportin 5 -0.0162366
CRTC1 CREB regulated transcription coactivator 1 -0.0162167
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -0.016203
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0161824
EXOC6B exocyst complex component 6B -0.0161797
RPS11 ribosomal protein S11 -0.0161742
UBTF upstream binding transcription factor, RNA polymerase I -0.0161685
MCM7 minichromosome maintenance complex component 7 -0.016162
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0161385
APTX aprataxin -0.0161368
NFIA nuclear factor I/A -0.0161364
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0161286
CERS6 ceramide synthase 6 -0.0160949
ZNF175 zinc finger protein 175 -0.0160854
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0160852
JAK1 Janus kinase 1 -0.0160682
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0160583
COA7 cytochrome c oxidase assembly factor 7 (putative) -0.0160442
TEX10 testis expressed 10 -0.0160376
SAFB2 scaffold attachment factor B2 -0.0159951
TMEM50B transmembrane protein 50B -0.0159781
EPB41 erythrocyte membrane protein band 4.1 -0.0159438
SCARB1 scavenger receptor class B, member 1 -0.0159407
POLH polymerase (DNA directed), eta -0.0159365
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.0159289
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0159259
PDCD6IP programmed cell death 6 interacting protein -0.0159001
GALM galactose mutarotase (aldose 1-epimerase) -0.0158877
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0158723
RHOH ras homolog family member H -0.0158591
EMSY EMSY transcriptional repressor, BRCA2 interacting -0.0158457
CAB39 calcium binding protein 39 -0.0158296
CDCA8 cell division cycle associated 8 -0.0157794
BIRC6 baculoviral IAP repeat containing 6 -0.0157724
RBM41 RNA binding motif protein 41 -0.0157409
SRPK1 SRSF protein kinase 1 -0.0157394
ZNF586 zinc finger protein 586 -0.0157328
MAST2 microtubule associated serine/threonine kinase 2 -0.01568
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0156731
ALMS1 Alstrom syndrome protein 1 -0.015671
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -0.0156676
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0156499
POM121 POM121 transmembrane nucleoporin -0.0156068
KPNB1 karyopherin (importin) beta 1 -0.0156005
DOCK11 dedicator of cytokinesis 11 -0.015597
ARMC1 armadillo repeat containing 1 -0.0155193
CCS copper chaperone for superoxide dismutase -0.0155162
LCLAT1 lysocardiolipin acyltransferase 1 -0.0155126
MACF1 microtubule-actin crosslinking factor 1 -0.0155101
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -0.0154748
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.0154606
SATB2 SATB homeobox 2 -0.0154562
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -0.0154505
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0154438
ATAD3B ATPase family, AAA domain containing 3B -0.0154242
AXIN1 axin 1 -0.0154125
ZC3H4 zinc finger CCCH-type containing 4 -0.0154091
TENT4A terminal nucleotidyltransferase 4A -0.0154079
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0153916
ZZZ3 zinc finger, ZZ-type containing 3 -0.0153622
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0153612
MRI1 methylthioribose-1-phosphate isomerase 1 -0.0153609
NUSAP1 nucleolar and spindle associated protein 1 -0.0153176
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0153058
CHD1L chromodomain helicase DNA binding protein 1-like -0.0153049
GRSF1 G-rich RNA sequence binding factor 1 -0.0152839
FLNB filamin B, beta -0.0152626
SPATA17 spermatogenesis associated 17 -0.0152465
FOXJ3 forkhead box J3 -0.0152302
STK4 serine/threonine kinase 4 -0.0152284
KNOP1 lysine-rich nucleolar protein 1 -0.015219
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -0.0152168
ZDHHC3 zinc finger, DHHC-type containing 3 -0.0152045
KDM1A lysine (K)-specific demethylase 1A -0.0151852
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.0151811
GSTO1 glutathione S-transferase omega 1 -0.0151546
PCGF3 polycomb group ring finger 3 -0.0151513
EIPR1 EARP complex and GARP complex interacting protein 1 -0.0151496
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0151399
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0151344
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.015119
UBE4B ubiquitination factor E4B -0.0151024
JMJD1C jumonji domain containing 1C -0.0151
TES testin LIM domain protein -0.0150847
TXNL1 thioredoxin-like 1 -0.0150716
ABI1 abl-interactor 1 -0.0150228
AVL9 AVL9 homolog (S. cerevisiase) -0.0150208
ZNF212 zinc finger protein 212 -0.0150126
NCOR1 nuclear receptor corepressor 1 -0.0150113
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -0.0149696
DMTF1 cyclin D binding myb-like transcription factor 1 -0.0149276
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0149264
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0149107
SRRM2 serine/arginine repetitive matrix 2 -0.014903
SEPTIN9 septin 9 -0.0148977
FNDC3B fibronectin type III domain containing 3B -0.014876
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -0.0148599
LPIN2 lipin 2 -0.0148486
RAI1 retinoic acid induced 1 -0.0148481
FN1 fibronectin 1 -0.0147785
RABEPK Rab9 effector protein with kelch motifs -0.0147476
RPS23 ribosomal protein S23 -0.0147468
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.014722
ARMC8 armadillo repeat containing 8 -0.0147183
WDR27 WD repeat domain 27 -0.0146944
LIN9 lin-9 DREAM MuvB core complex component -0.0146732
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.0146505
AKIRIN2 akirin 2 -0.0146502
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0146491
EIF3E eukaryotic translation initiation factor 3, subunit E -0.0146117
ACSF3 acyl-CoA synthetase family member 3 -0.0146022