K562_SNS-314 Mesylate_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SNS-314 Mesylate 10µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_SNS-314 Mesylate_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
STXBP5 syntaxin binding protein 5 (tomosyn) 0.117614
MUSK muscle, skeletal, receptor tyrosine kinase 0.111942
ZEB2 zinc finger E-box binding homeobox 2 0.0895694
NIBAN1 niban apoptosis regulator 1 0.0894927
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.0863597
ZCCHC7 zinc finger, CCHC domain containing 7 0.0837196
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0768584
PRKCB protein kinase C, beta 0.0697963
GSE1 Gse1 coiled-coil protein 0.0690188
CUX1 cut-like homeobox 1 0.0643595
ANTXR2 anthrax toxin receptor 2 0.0632758
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0626617
MED13L mediator complex subunit 13-like 0.0614674
MAML2 mastermind-like 2 (Drosophila) 0.0604708
MBNL2 muscleblind-like splicing regulator 2 0.0599542
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0592674
CPED1 cadherin-like and PC-esterase domain containing 1 0.0570032
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.0561252
DCAF7 DDB1 and CUL4 associated factor 7 0.0551811
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0541506
HBG2 hemoglobin, gamma G 0.0534977
JMJD1C jumonji domain containing 1C 0.0530293
RNF24 ring finger protein 24 0.0520901
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0504665
MARCHF1 membrane associated ring-CH-type finger 1 0.0496857
LARP4B La ribonucleoprotein domain family, member 4B 0.0495743
DSTYK dual serine/threonine and tyrosine protein kinase 0.0495243
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0493308
TBC1D5 TBC1 domain family, member 5 0.0484885
ATF5 activating transcription factor 5 0.0468951
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0463087
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0460974
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.045306
NLK nemo-like kinase 0.0452708
BCAS3 breast carcinoma amplified sequence 3 0.044327
ADGRV1 adhesion G protein-coupled receptor V1 0.0439204
NKTR natural killer cell triggering receptor 0.0428499
ZNF609 zinc finger protein 609 0.0417711
ANKRD28 ankyrin repeat domain 28 0.0412058
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0407026
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0405142
SLA2 Src-like-adaptor 2 0.040203
GAB2 GRB2-associated binding protein 2 0.0401433
WARS1 tryptophanyl-tRNA synthetase 1 0.0378289
AARS1 alanyl-tRNA synthetase 1 0.0376384
CMIP c-Maf inducing protein 0.0376335
DYM dymeclin 0.03741
SLC39A11 solute carrier family 39, member 11 0.0373122
RHOBTB3 Rho-related BTB domain containing 3 0.0370765
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.0370706
BMP2K BMP2 inducible kinase 0.036613
RAB27B RAB27B, member RAS oncogene family 0.0360075
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0353062
PEAK1 pseudopodium-enriched atypical kinase 1 0.035265
ESYT1 extended synaptotagmin-like protein 1 0.0350803
ATXN7L1 ataxin 7-like 1 0.0347648
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.034746
ABHD3 abhydrolase domain containing 3 0.034281
TTC7B tetratricopeptide repeat domain 7B 0.0341881
RBM39 RNA binding motif protein 39 0.0340883
EIF5B eukaryotic translation initiation factor 5B 0.0340816
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.033835
BIRC6 baculoviral IAP repeat containing 6 0.0334651
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0333304
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0333217
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0332795
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.0331768
EXOC4 exocyst complex component 4 0.0331307
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.033037
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0327492
IARS1 isoleucyl-tRNA synthetase 1 0.0324839
AVL9 AVL9 homolog (S. cerevisiase) 0.0323159
ORAI2 ORAI calcium release-activated calcium modulator 2 0.031928
HSPG2 heparan sulfate proteoglycan 2 0.0318528
GRB10 growth factor receptor-bound protein 10 0.0318173
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.0316024
KAZN kazrin, periplakin interacting protein 0.0314827
N4BP2L2 NEDD4 binding protein 2-like 2 0.0314754
WRN Werner syndrome, RecQ helicase-like 0.0314597
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.031303
RPL32 ribosomal protein L32 0.0312104
MEF2C myocyte enhancer factor 2C 0.0311034
TPR translocated promoter region, nuclear basket protein 0.0310785
ABHD2 abhydrolase domain containing 2 0.0310555
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.031047
YARS1 tyrosyl-tRNA synthetase 1 0.0310396
AIG1 androgen-induced 1 0.0309968
ZBTB35 zinc finger and BTB domain containing 35 0.0309166
HIP1 huntingtin interacting protein 1 0.0308922
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0305212
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.0302199
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.0301462
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0301172
NF1 neurofibromin 1 0.0299919
DST dystonin 0.0299439
RESF1 retroelement silencing factor 1 0.0299341
SON SON DNA binding protein 0.0297166
ZFAND3 zinc finger, AN1-type domain 3 0.0296973
SOGA1 suppressor of glucose, autophagy associated 1 0.0292503
MECR mitochondrial trans-2-enoyl-CoA reductase 0.0290517
DNPEP aspartyl aminopeptidase 0.0289387
PRR16 proline rich 16 0.0288976
MBTD1 mbt domain containing 1 0.0286403
LARP4 La ribonucleoprotein domain family, member 4 0.0284772
CCAR1 cell division cycle and apoptosis regulator 1 0.0284708
DOCK11 dedicator of cytokinesis 11 0.0283937
GMPS guanine monphosphate synthase 0.0283449
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0281504
TPM3 tropomyosin 3 0.0278513
ACSL4 acyl-CoA synthetase long-chain family member 4 0.0276523
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0276175
VWA8 von Willebrand factor A domain containing 8 0.0275326
BCR breakpoint cluster region 0.0274633
RPS6 ribosomal protein S6 0.0273713
ACBD6 acyl-CoA binding domain containing 6 0.0273487
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.0272493
ZYG11B zyg-11 family member B, cell cycle regulator 0.0270285
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0270106
MBNL1 muscleblind-like splicing regulator 1 0.0267402
NFE2L2 nuclear factor, erythroid 2-like 2 0.0266953
NAV1 neuron navigator 1 0.0266816
RBBP4 retinoblastoma binding protein 4 0.0265943
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.026534
ACER3 alkaline ceramidase 3 0.0264969
PDZD8 PDZ domain containing 8 0.0264575
GRB2 growth factor receptor-bound protein 2 0.0263982
AAK1 AP2 associated kinase 1 0.026383
ZNF721 zinc finger protein 721 0.0262616
CDC45 cell division cycle 45 0.0261683
FLNA filamin A, alpha 0.0261432
NIPBL Nipped-B homolog (Drosophila) 0.0261354
SERP1 stress-associated endoplasmic reticulum protein 1 0.0261083
ZMYM4 zinc finger, MYM-type 4 0.0258831
CHD9 chromodomain helicase DNA binding protein 9 0.0257904
HLA-E major histocompatibility complex, class I, E 0.025783
TTC3 tetratricopeptide repeat domain 3 0.0257117
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.0257112
ASXL2 additional sex combs like transcriptional regulator 2 0.0256945
NOL4L nucleolar protein 4-like 0.0256526
FNBP4 formin binding protein 4 0.0254047
R3HDM2 R3H domain containing 2 0.0252618
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.0252501
CELF2 CUGBP, Elav-like family member 2 0.0252186
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0249692
UNC13D unc-13 homolog D (C. elegans) 0.0249502
DMXL1 Dmx-like 1 0.0248792
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 0.0248506
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0247612
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0246963
HIPK2 homeodomain interacting protein kinase 2 0.0246304
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.0245829
P3H1 prolyl 3-hydroxylase 1 0.0243041
RCOR1 REST corepressor 1 0.0242962
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.0242828
PHF14 PHD finger protein 14 0.0242756
EHBP1 EH domain binding protein 1 0.0242399
ZNF83 zinc finger protein 83 0.0242333
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0242133
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0241413
DIAPH1 diaphanous-related formin 1 0.0239981
SEPTIN11 septin 11 0.0239503
TEX15 testis expressed 15 0.0237492
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0237229
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0237099
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0236711
NFIA nuclear factor I/A 0.0236455
RABGAP1L RAB GTPase activating protein 1-like 0.0235676
NCAM2 neural cell adhesion molecule 2 0.0234133
KSR1 kinase suppressor of ras 1 0.0232581
NEMF nuclear export mediator factor 0.0232489
DEPDC5 DEP domain containing 5 0.0230995
CEP350 centrosomal protein 350kDa 0.0230663
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.0230525
EPS15 epidermal growth factor receptor pathway substrate 15 0.023048
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0230168
STX8 syntaxin 8 0.0230128
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 0.022972
POTEF POTE ankyrin domain family, member F 0.0229069
ADAM10 ADAM metallopeptidase domain 10 0.0228792
CANX calnexin 0.022814
TSPAN5 tetraspanin 5 0.0227949
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0227495
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0227232
CDK19 cyclin-dependent kinase 19 0.0226926
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0226903
STAT5B signal transducer and activator of transcription 5B 0.0225461
RPN2 ribophorin II 0.0224537
FNDC3B fibronectin type III domain containing 3B 0.0223882
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.0223517
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0221874
COMT catechol-O-methyltransferase 0.0221315
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0220903
RNF157 ring finger protein 157 0.0220364
RPL35A ribosomal protein L35a 0.0219858
AKAP9 A kinase (PRKA) anchor protein 9 0.0218835
GLO1 glyoxalase I 0.0217917
CAPN1 calpain 1, (mu/I) large subunit 0.0217499
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 0.0216575
TRRAP transformation/transcription domain-associated protein 0.0216305
PDCD6IP programmed cell death 6 interacting protein 0.0216102
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0215979
RTN3 reticulon 3 0.0215057
ATP5F1B ATP synthase F1 subunit beta 0.0214938
MDN1 MDN1, midasin homolog (yeast) 0.0214728
SUMF1 sulfatase modifying factor 1 0.0213709
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0212758
SLC35F2 solute carrier family 35, member F2 0.0211794
MAVS mitochondrial antiviral signaling protein 0.0211194
MCM4 minichromosome maintenance complex component 4 0.0211037
TLE5 TLE family member 5, transcriptional modulator 0.0209506
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.0209138
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0208647
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.020855
TCF12 transcription factor 12 0.0208201
RACK1 receptor for activated C kinase 1 0.020794
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0207933
IQCB1 IQ motif containing B1 0.0207615
TNRC18 trinucleotide repeat containing 18 0.0207468
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0207287
OSBPL6 oxysterol binding protein-like 6 0.0207097
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0206947
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.0205877
LONP2 lon peptidase 2, peroxisomal 0.020587
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.0205845
LAMP2 lysosomal-associated membrane protein 2 0.0205781
ANKRD11 ankyrin repeat domain 11 0.0205609
CDK6 cyclin-dependent kinase 6 0.0205482
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.0204591
LRP12 low density lipoprotein receptor-related protein 12 0.0203034
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.0203031
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.0202412
ZFYVE9 zinc finger, FYVE domain containing 9 0.0201534
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0201333
QTMAN queuosine-tRNA mannosyltransferase 0.0201037
GRAP2 GRB2-related adaptor protein 2 0.0200726
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.0200658
TMEM267 transmembrane protein 267 0.0200171
MGME1 mitochondrial genome maintenance exonuclease 1 0.0199988
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.0199824
CIRSR corepressor of RBPJ and splicing regulator 0.0199662
DPY19L3 dpy-19-like 3 (C. elegans) 0.0199326
KDM3B lysine (K)-specific demethylase 3B 0.0199134
CDCP1 CUB domain containing protein 1 0.0199114
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0198739
USP33 ubiquitin specific peptidase 33 0.0198553
ETV6 ets variant 6 0.0198552
DCP2 decapping mRNA 2 0.0198292
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0196989
GOLIM4 golgi integral membrane protein 4 0.0196909
PLEC plectin 0.0196819
RNF111 ring finger protein 111 0.0196242
NCOA7 nuclear receptor coactivator 7 0.0196218
IREB2 iron-responsive element binding protein 2 0.0195544
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0194139
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0193944
PRKCSH protein kinase C substrate 80K-H 0.01939
KIF1B kinesin family member 1B 0.0193743
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0193666
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0193527
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.0193136
CLIC4 chloride intracellular channel 4 0.0192962
R3HDM1 R3H domain containing 1 0.0192938
CHPT1 choline phosphotransferase 1 0.0192722
NSUN6 NOP2/Sun domain family, member 6 0.0192068
CPQ carboxypeptidase Q 0.0191996
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0191896
RBM20 RNA binding motif protein 20 0.0191117
AFG2A AFG2 AAA ATPase homolog A 0.0190493
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.0190361
CEP152 centrosomal protein 152kDa 0.019008
RDH10 retinol dehydrogenase 10 (all-trans) 0.0189748
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.0189583
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.0189146
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.0188741
MYO16 myosin XVI 0.0188411
CBFB core-binding factor, beta subunit 0.0187997
BRD1 bromodomain containing 1 0.0187789
CIZ1 CDKN1A interacting zinc finger protein 1 0.018761
SLMAP sarcolemma associated protein 0.0187413
PDS5A PDS5 cohesin associated factor A 0.0186692
TPGS2 tubulin polyglutamylase complex subunit 2 0.0186397
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0186051
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.0185765
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0184651
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.0184324
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.0184198
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0183594
ARHGAP6 Rho GTPase activating protein 6 0.0183496
IQSEC2 IQ motif and Sec7 domain 2 0.0183291
FBXO31 F-box protein 31 0.0183131
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0182936
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0182466
PTCD3 pentatricopeptide repeat domain 3 0.0182338
AFDN afadin, adherens junction formation factor 0.0182305
PCDH9 protocadherin 9 0.0181815
FAT1 FAT atypical cadherin 1 0.0181696
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0181593
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.0181493
BLTP3A bridge-like lipid transfer protein family member 3A 0.0181301
PHGDH phosphoglycerate dehydrogenase 0.0181283
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0181112
ZBTB44 zinc finger and BTB domain containing 44 0.0180614
GOPC golgi-associated PDZ and coiled-coil motif containing 0.0180215
HSPA4L heat shock 70kDa protein 4-like 0.0179839
TASOR2 transcription activation suppressor family member 2 0.0179772
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.0179299
SNX29 sorting nexin 29 0.0179229
MAP1B microtubule-associated protein 1B 0.0179193
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0179143
SLC38A9 solute carrier family 38, member 9 0.0179051
RPL27 ribosomal protein L27 0.0178975
FCHSD2 FCH and double SH3 domains 2 0.0178938
SLC38A1 solute carrier family 38, member 1 0.0178826
COPG2 coatomer protein complex, subunit gamma 2 0.0178745
CLCN7 chloride channel, voltage-sensitive 7 0.0178294
TTI1 TELO2 interacting protein 1 0.0178137
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 0.0177955
ATF7IP2 activating transcription factor 7 interacting protein 2 0.0177894
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0177459
CD47 CD47 molecule 0.0177031
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.0176827
RPL7 ribosomal protein L7 0.0176573
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.0176396
TWSG1 twisted gastrulation BMP signaling modulator 1 0.0175937
EEF2 eukaryotic translation elongation factor 2 0.0175868
RO60 Ro60, Y RNA binding protein 0.0175703
RRBP1 ribosome binding protein 1 0.0175638
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.0175613
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.0175334
ZNF260 zinc finger protein 260 0.0175308
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.0175105
BICD1 bicaudal D homolog 1 (Drosophila) 0.0174612
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.0174169
STX5 syntaxin 5 0.017345
FBXO11 F-box protein 11 0.0172243
HBA1 hemoglobin, alpha 1 0.0171577
EMID1 EMI domain containing 1 0.017147
MANBA mannosidase, beta A, lysosomal 0.0171288
SAR1A secretion associated, Ras related GTPase 1A 0.0171262
ATF7IP activating transcription factor 7 interacting protein 0.0171181
SLC38A7 solute carrier family 38, member 7 0.0170959
SLC44A5 solute carrier family 44, member 5 0.0170951
PTPRC protein tyrosine phosphatase, receptor type, C 0.0170402
BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 0.0169108
TBRG1 transforming growth factor beta regulator 1 0.0168809
HSPA1A heat shock 70kDa protein 1A 0.0168767
FHIT fragile histidine triad 0.0168566
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.0167916
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.0167755
SCCPDH saccharopine dehydrogenase (putative) 0.0166899
NCOA1 nuclear receptor coactivator 1 0.0166831
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0166019
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.0165993
GMCL1 germ cell-less, spermatogenesis associated 1 0.0165949
NT5DC3 5'-nucleotidase domain containing 3 0.0165925
ATP13A2 ATPase type 13A2 0.0165543
CORO1C coronin, actin binding protein, 1C 0.0165283
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 0.0164611
D2HGDH D-2-hydroxyglutarate dehydrogenase 0.0164604
BCLAF1 BCL2-associated transcription factor 1 0.0164009
MARCHF6 membrane associated ring-CH-type finger 6 0.016394
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 0.0163905
ZNF644 zinc finger protein 644 0.0163499
GALM galactose mutarotase (aldose 1-epimerase) 0.0163297
ZNF33A zinc finger protein 33A 0.0163107
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.0162635
ZNF367 zinc finger protein 367 0.0162607
INVS inversin 0.0161709
ORC6 origin recognition complex, subunit 6 0.0160732
GOLGA3 golgin A3 0.01607
LETMD1 LETM1 domain containing 1 0.0160645
SLC38A10 solute carrier family 38, member 10 0.0160379
ZNFX1 zinc finger, NFX1-type containing 1 0.0159516
FBXL20 F-box and leucine-rich repeat protein 20 0.015936
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0159135
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.0158689
MYO9A myosin IXA 0.0158503
ABI2 abl-interactor 2 0.0158488
MIA3 melanoma inhibitory activity family, member 3 0.0158275
PIAS2 protein inhibitor of activated STAT, 2 0.0158268
SMIM8 small integral membrane protein 8 0.0158192
CFAP70 cilia and flagella associated protein 70 0.0158043
PFAS phosphoribosylformylglycinamidine synthase 0.0157778
RICTOR RPTOR independent companion of MTOR, complex 2 0.015747
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.0157381
MCU mitochondrial calcium uniporter 0.0156982
TAPBP TAP binding protein (tapasin) 0.015697
CDC37 cell division cycle 37 0.0156938
ZC3H18 zinc finger CCCH-type containing 18 0.0156864
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0156391
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0155959
CYSTM1 cysteine-rich transmembrane module containing 1 0.0155944
EIF4H eukaryotic translation initiation factor 4H 0.0155896
FRYL FRY-like 0.0155312
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.015528
CATSPERB catsper channel auxiliary subunit beta 0.0155055
CSDE1 cold shock domain containing E1, RNA-binding 0.0154805
CTSD cathepsin D 0.0154784
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0154676
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0154093
FUCA2 fucosidase, alpha-L- 2, plasma 0.0153956
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.0153813
TXNL4A thioredoxin-like 4A 0.0153676
PHKB phosphorylase kinase, beta 0.0153655
SETD1B SET domain containing 1B 0.0153578
WDR36 WD repeat domain 36 0.0153542
FOXP1 forkhead box P1 0.0153511
RCSD1 RCSD domain containing 1 0.0153428
SGPP1 sphingosine-1-phosphate phosphatase 1 0.0153296
NUCB2 nucleobindin 2 0.0153275
COMMD1 copper metabolism (Murr1) domain containing 1 0.0153146
FAM184A family with sequence similarity 184, member A 0.0153002
RPL11 ribosomal protein L11 0.0152854
CCPG1 cell cycle progression 1 0.0152708
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.015269
TFAM transcription factor A, mitochondrial 0.0152554
TRA2B transformer 2 beta homolog (Drosophila) 0.0152479
CYB561 cytochrome b561 0.0152424
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.0152311
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.015178
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.0151758
SCAND3 SCAN domain containing 3 0.0151125
TRAPPC9 trafficking protein particle complex 9 0.0151051
OXSR1 oxidative stress responsive 1 0.0150845
CEPT1 choline/ethanolamine phosphotransferase 1 0.0150645
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.0150527
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.0150423
FBXO22 F-box protein 22 0.0150208
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.0149998
FAR1 fatty acyl CoA reductase 1 0.014983
RAB27A RAB27A, member RAS oncogene family 0.0149673
HCFC1 host cell factor C1 0.0149575
WNT5B wingless-type MMTV integration site family, member 5B 0.0149464
SREBF1 sterol regulatory element binding transcription factor 1 0.0149401
POC5 POC5 centriolar protein 0.0149211
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0148816
SPIDR scaffolding protein involved in DNA repair 0.0148792
LONP1 lon peptidase 1, mitochondrial 0.0148576
DENND5B DENN/MADD domain containing 5B 0.0148437
RUSC2 RUN and SH3 domain containing 2 0.0148248
FBXL17 F-box and leucine-rich repeat protein 17 0.0148215
ERBIN erbb2 interacting protein 0.0147946
TMEM117 transmembrane protein 117 0.0147613
SARAF store-operated calcium entry-associated regulatory factor 0.0147485
SCYL2 SCY1-like 2 (S. cerevisiae) 0.0147188
SPRED2 sprouty-related, EVH1 domain containing 2 0.0147177
DNM1 dynamin 1 0.0147164
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0147003
PARD3 par-3 family cell polarity regulator 0.01469
CTCF CCCTC-binding factor (zinc finger protein) 0.0146647
SENP1 SUMO1/sentrin specific peptidase 1 0.0146539
CEP290 centrosomal protein 290kDa 0.0146395
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 0.0145861
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0145813
CREB3L1 cAMP responsive element binding protein 3-like 1 0.0145237
PHACTR2 phosphatase and actin regulator 2 0.0145196
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.0144828
NEBL nebulette 0.0144669
ALPK1 alpha-kinase 1 0.0144547
ZBTB41 zinc finger and BTB domain containing 41 0.0144504
HMOX2 heme oxygenase 2 0.0144288
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0144226
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0144076
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 0.0144031
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0143904
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.0143887
MRE11 MRE11 homolog, double strand break repair nuclease 0.0143879
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.0143874
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0143853
MACROD2 MACRO domain containing 2 0.0143738
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.0143609
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0143577
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0143508
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.0143303
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.0143297
APTX aprataxin 0.0143133
RPS16 ribosomal protein S16 0.0142733
XPOT exportin, tRNA 0.014258
CARS1 cysteinyl-tRNA synthetase 1 0.0142412
HEPH hephaestin 0.0142068
FAM241A family with sequence similarity 241 member A 0.0142049
CALR calreticulin 0.0141923
WDR82 WD repeat domain 82 0.0141786
TMEM44 transmembrane protein 44 0.0141748
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.0141688
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.0141621
EXOC6 exocyst complex component 6 0.014146
C16ORF95 chromosome 16 open reading frame 95 0.0141174
CYRIB CYFIP related Rac1 interactor B 0.0140872
PDLIM5 PDZ and LIM domain 5 0.0140775
TLK1 tousled-like kinase 1 0.014073
MRNIP MRN complex interacting protein 0.0140672
BAG6 BCL2-associated athanogene 6 0.0140548
HBS1L HBS1-like translational GTPase 0.0140435
ZNF253 zinc finger protein 253 0.0140418
SYMPK symplekin 0.0140163
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0140019
CDK17 cyclin-dependent kinase 17 0.0139773
CRTC1 CREB regulated transcription coactivator 1 0.0139724
QSER1 glutamine and serine rich 1 0.0139664

decreased expression

Symbol Name Standardized Value
SMYD3 SET and MYND domain containing 3 -0.158969
ENO1 enolase 1, (alpha) -0.133188
EPB41 erythrocyte membrane protein band 4.1 -0.112862
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.109826
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.104503
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.100328
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0955982
ARL15 ADP-ribosylation factor-like 15 -0.0784876
TGFB1 transforming growth factor, beta 1 -0.0744402
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0681487
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0676185
ACTN4 actinin, alpha 4 -0.0645838
FBXL13 F-box and leucine-rich repeat protein 13 -0.0631897
MKI67 marker of proliferation Ki-67 -0.0605019
FDPS farnesyl diphosphate synthase -0.0599366
KRT8 keratin 8, type II -0.0598117
FAM13A family with sequence similarity 13, member A -0.0580891
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0570411
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0566859
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0550447
FAF1 Fas (TNFRSF6) associated factor 1 -0.0548878
LDHA lactate dehydrogenase A -0.0544846
ESYT2 extended synaptotagmin-like protein 2 -0.0540736
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0538119
PRKCA protein kinase C, alpha -0.0524017
ACSS2 acyl-CoA synthetase short-chain family member 2 -0.0522808
KIF2A kinesin heavy chain member 2A -0.0521956
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0520338
NMU neuromedin U -0.0513489
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0511653
PKM pyruvate kinase, muscle -0.0510565
MACF1 microtubule-actin crosslinking factor 1 -0.0510373
STRN3 striatin, calmodulin binding protein 3 -0.0492441
KLHDC10 kelch domain containing 10 -0.0464271
DARS1 aspartyl-tRNA synthetase 1 -0.0458397
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0457849
CENPP centromere protein P -0.0457484
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0454819
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0448704
MARCHF3 membrane associated ring-CH-type finger 3 -0.0447963
SAMD4A sterile alpha motif domain containing 4A -0.0444392
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0443152
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0442262
DNM2 dynamin 2 -0.0435772
STAG2 stromal antigen 2 -0.0434315
PICALM phosphatidylinositol binding clathrin assembly protein -0.0432771
KDM4B lysine (K)-specific demethylase 4B -0.0432518
ESRRB estrogen-related receptor beta -0.0430558
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0428918
SORBS1 sorbin and SH3 domain containing 1 -0.0425487
SRRM2 serine/arginine repetitive matrix 2 -0.0412857
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0404125
ZMYND8 zinc finger, MYND-type containing 8 -0.0403373
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0403245
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0396369
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0391888
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0389566
LDLR low density lipoprotein receptor -0.0389015
LIMS1 LIM and senescent cell antigen-like domains 1 -0.037675
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0375126
GTF2IRD1 GTF2I repeat domain containing 1 -0.0370178
CD2AP CD2-associated protein -0.0364197
SSR1 signal sequence receptor, alpha -0.0355184
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0344755
FAM178B family with sequence similarity 178, member B -0.03414
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0335049
CMC4 C-x(9)-C motif containing 4 -0.0329054
KDM6A lysine (K)-specific demethylase 6A -0.0328093
CNTNAP2 contactin associated protein-like 2 -0.032699
GLUL glutamate-ammonia ligase -0.0326146
MAPK1 mitogen-activated protein kinase 1 -0.0323316
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0320792
JARID2 jumonji, AT rich interactive domain 2 -0.0319398
TNIK TRAF2 and NCK interacting kinase -0.0315073
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0313279
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0312539
RLF rearranged L-myc fusion -0.0309417
RPS8 ribosomal protein S8 -0.0309304
USP15 ubiquitin specific peptidase 15 -0.0307771
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0306485
RPLP2 ribosomal protein, large, P2 -0.0306135
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0305816
RELN reelin -0.030309
EIF3I eukaryotic translation initiation factor 3, subunit I -0.0303068
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0302569
SQSTM1 sequestosome 1 -0.029727
BRCA1 breast cancer 1, early onset -0.0297004
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0295786
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.0294169
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0291376
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0290849
PRRC2C proline-rich coiled-coil 2C -0.0286384
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0283586
CLINT1 clathrin interactor 1 -0.0280949
LRRC8B leucine rich repeat containing 8 family, member B -0.0279395
FCHO2 FCH domain only 2 -0.0278319
KMT2A lysine (K)-specific methyltransferase 2A -0.0278182
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0277556
SEC24A SEC24 family member A -0.0277092
FBXO42 F-box protein 42 -0.0275908
WWOX WW domain containing oxidoreductase -0.0273994
TENM1 teneurin transmembrane protein 1 -0.0270001
SIK3 SIK family kinase 3 -0.0269415
NGLY1 N-glycanase 1 -0.0267853
UBC ubiquitin C -0.0267744
RBM14-RBM4 RBM14-RBM4 readthrough -0.0265898
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -0.0265144
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0264411
UBAC1 UBA domain containing 1 -0.0263005
PDE8A phosphodiesterase 8A -0.0262759
RBM15 RNA binding motif protein 15 -0.026264
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.0261954
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.0260977
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0257893
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.0257584
ZFYVE28 zinc finger, FYVE domain containing 28 -0.025707
TXNRD1 thioredoxin reductase 1 -0.0256871
KIF20B kinesin family member 20B -0.0255664
YEATS2 YEATS domain containing 2 -0.0253963
MYO18B myosin XVIIIB -0.0252955
DENND1A DENN/MADD domain containing 1A -0.0252004
KMT2C lysine (K)-specific methyltransferase 2C -0.0251506
TAC4 tachykinin 4 (hemokinin) -0.0250729
HDLBP high density lipoprotein binding protein -0.0248478
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0248014
GOLGA2 golgin A2 -0.0246653
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.0245975
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.0242891
MED12 mediator complex subunit 12 -0.0238379
GATAD2B GATA zinc finger domain containing 2B -0.0237614
POM121C POM121 transmembrane nucleoporin C -0.0237337
RNF217 ring finger protein 217 -0.0237087
PRELID2 PRELI domain containing 2 -0.0237004
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0236948
ARHGAP21 Rho GTPase activating protein 21 -0.0235242
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0234563
BCOR BCL6 corepressor -0.0233069
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0233012
ZC3H4 zinc finger CCCH-type containing 4 -0.0232619
RHOA ras homolog family member A -0.0230803
BST2 bone marrow stromal cell antigen 2 -0.0229053
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0228983
INSIG1 insulin induced gene 1 -0.0228906
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0228354
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0228127
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.0227147
NUMB numb homolog (Drosophila) -0.0226729
TNRC6B trinucleotide repeat containing 6B -0.0226425
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -0.0225744
KDM5B lysine (K)-specific demethylase 5B -0.0223783
NUSAP1 nucleolar and spindle associated protein 1 -0.0223481
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0221521
RANBP9 RAN binding protein 9 -0.0220662
SBF2 SET binding factor 2 -0.0220113
PGK1 phosphoglycerate kinase 1 -0.0219386
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.0219182
KRT19 keratin 19, type I -0.0218544
MARCHF7 membrane associated ring-CH-type finger 7 -0.0217029
PCSK7 proprotein convertase subtilisin/kexin type 7 -0.0215504
CUL1 cullin 1 -0.0214983
CEP104 centrosomal protein 104kDa -0.0214309
DYNC2I1 dynein 2 intermediate chain 1 -0.0212812
POU2F1 POU class 2 homeobox 1 -0.0210627
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0209502
ZNF292 zinc finger protein 292 -0.0209239
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.0206378
NOP58 NOP58 ribonucleoprotein -0.020541
UBAP2 ubiquitin associated protein 2 -0.0205387
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.0205356
POFUT4 protein O-fucosyltransferase 4 -0.0204603
RPL28 ribosomal protein L28 -0.0204449
ATAD2 ATPase family, AAA domain containing 2 -0.0203555
FNDC3A fibronectin type III domain containing 3A -0.0203288
GDI2 GDP dissociation inhibitor 2 -0.0203052
ANKRD17 ankyrin repeat domain 17 -0.0202228
BTBD7 BTB (POZ) domain containing 7 -0.0202195
PHTF2 putative homeodomain transcription factor 2 -0.0202045
CEP85L centrosomal protein 85kDa-like -0.0201885
RBL2 retinoblastoma-like 2 -0.0201701
NUP214 nucleoporin 214kDa -0.0200869
DENND5A DENN/MADD domain containing 5A -0.02007
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0197927
RPS21 ribosomal protein S21 -0.0197746
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0197047
ARID1A AT rich interactive domain 1A (SWI-like) -0.0196138
KIF15 kinesin family member 15 -0.0195055
TXNIP thioredoxin interacting protein -0.0194278
FAM193A family with sequence similarity 193, member A -0.019367
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) -0.0193486
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -0.0193483
RAB6A RAB6A, member RAS oncogene family -0.0190724
KAT6A K(lysine) acetyltransferase 6A -0.0190381
SREBF2 sterol regulatory element binding transcription factor 2 -0.0190313
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0189381
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0186873
MORC3 MORC family CW-type zinc finger 3 -0.0186867
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.0186798
TMOD1 tropomodulin 1 -0.0186385
FUBP3 far upstream element (FUSE) binding protein 3 -0.0185809
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.018531
ZNF121 zinc finger protein 121 -0.0183652
LOC112694756 uncharaterized LOC112694756 -0.0183432
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0183357
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0182842
GMPR guanosine monophosphate reductase -0.0182729
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0181548
CCNY cyclin Y -0.0181235
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.018074
TNPO2 transportin 2 -0.0180203
DENND4A DENN/MADD domain containing 4A -0.0180195
CDYL chromodomain protein, Y-like -0.0179996
TRAP1 TNF receptor-associated protein 1 -0.0179306
PLCD1 phospholipase C, delta 1 -0.0178925
LRRC61 leucine rich repeat containing 61 -0.0178723
H4C8 H4 clustered histone 8 -0.0178545
SRSF10 serine/arginine-rich splicing factor 10 -0.0178104
MYLIP myosin regulatory light chain interacting protein -0.0178072
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0178059
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0177932
SCAF8 SR-related CTD-associated factor 8 -0.0176822
TAOK3 TAO kinase 3 -0.0176693
PTK2B protein tyrosine kinase 2 beta -0.0176518
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -0.0176362
PPARD peroxisome proliferator-activated receptor delta -0.017598
ANKRD13C ankyrin repeat domain 13C -0.01759
PRKCI protein kinase C, iota -0.0175456
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0175293
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0174973
FANCA Fanconi anemia, complementation group A -0.0174175
KPNB1 karyopherin (importin) beta 1 -0.0173866
TPI1 triosephosphate isomerase 1 -0.0173173
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0172188
FAM168A family with sequence similarity 168, member A -0.0171875
CFAP20DC CFAP20 domain containing -0.0171528
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.0171441
GEMIN5 gem (nuclear organelle) associated protein 5 -0.0171116
RPS7 ribosomal protein S7 -0.0171067
LBR lamin B receptor -0.0170955
WDR33 WD repeat domain 33 -0.0170885
AKAP8L A kinase (PRKA) anchor protein 8-like -0.0170875
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0170695
THEM4 thioesterase superfamily member 4 -0.0170673
RREB1 ras responsive element binding protein 1 -0.0170138
CHML choroideremia-like (Rab escort protein 2) -0.0169884
GPHRA golgi pH regulator A -0.0169097
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0168862
EGFL7 EGF-like-domain, multiple 7 -0.0168638
DEAF1 DEAF1 transcription factor -0.0168527
TET3 tet methylcytosine dioxygenase 3 -0.0168356
DIAPH3 diaphanous-related formin 3 -0.016798
NPEPPS aminopeptidase puromycin sensitive -0.0167707
CKB creatine kinase, brain -0.0167263
METAP1 methionyl aminopeptidase 1 -0.0166782
WDR26 WD repeat domain 26 -0.0166595
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0166106
SNX3 sorting nexin 3 -0.0166104
AHDC1 AT hook, DNA binding motif, containing 1 -0.0166103
HBE1 hemoglobin, epsilon 1 -0.0166035
ALKBH5 AlkB family member 5, RNA demethylase -0.0165833
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -0.0165675
WDR20 WD repeat domain 20 -0.0165416
TTC1 tetratricopeptide repeat domain 1 -0.0165221
FN1 fibronectin 1 -0.0164928
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.01649
CD164 CD164 molecule, sialomucin -0.0164526
TMEM135 transmembrane protein 135 -0.0164246
BCAP31 B-cell receptor-associated protein 31 -0.0164125
GON4L gon-4-like (C. elegans) -0.0163934
DLG5 discs, large homolog 5 (Drosophila) -0.0163752
SCG3 secretogranin III -0.0163657
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0163301
USP37 ubiquitin specific peptidase 37 -0.0162912
UHMK1 U2AF homology motif (UHM) kinase 1 -0.0162881
NUP205 nucleoporin 205kDa -0.0162815
SBNO1 strawberry notch homolog 1 (Drosophila) -0.0162749
ACACA acetyl-CoA carboxylase alpha -0.0162741
AK4 adenylate kinase 4 -0.016259
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -0.0162565
TGFBR3 transforming growth factor, beta receptor III -0.0162513
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -0.0162181
SCFD2 sec1 family domain containing 2 -0.0160478
RAI14 retinoic acid induced 14 -0.0160449
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.0160052
SACK1A scaffolding CK1 anchoring protein A -0.015999
SFSWAP splicing factor, suppressor of white-apricot family -0.015944
ANKRD12 ankyrin repeat domain 12 -0.0158548
ECPAS Ecm29 proteasome adaptor and scaffold -0.0158536
KRT18 keratin 18, type I -0.0158042
SIRT2 sirtuin 2 -0.0157992
TUBB tubulin, beta class I -0.0157394
SFXN1 sideroflexin 1 -0.0157331
C6ORF62 chromosome 6 open reading frame 62 -0.0157211
PFN1 profilin 1 -0.0156703
GDNF glial cell derived neurotrophic factor -0.0156158
ZC3H7A zinc finger CCCH-type containing 7A -0.0155575
BHLHE40 basic helix-loop-helix family, member e40 -0.0155505
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.0154407
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -0.0154228
TFR2 transferrin receptor 2 -0.0154201
IGF2R insulin-like growth factor 2 receptor -0.0154146
SMC5 structural maintenance of chromosomes 5 -0.0153516
RHBDD2 rhomboid domain containing 2 -0.0153332
YDJC YdjC homolog (bacterial) -0.0152989
PTPRA protein tyrosine phosphatase, receptor type, A -0.0152778
RPL3 ribosomal protein L3 -0.0152625
NPAT nuclear protein, ataxia-telangiectasia locus -0.0152306
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0152296
FOXK2 forkhead box K2 -0.0152248
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -0.0151793
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.015166
TNIP1 TNFAIP3 interacting protein 1 -0.0151508
KIAA1328 KIAA1328 -0.0151461
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.015126
EEF2K eukaryotic elongation factor 2 kinase -0.0151205
CAPRIN1 cell cycle associated protein 1 -0.0151201
MACROD1 MACRO domain containing 1 -0.0150784
TRIM24 tripartite motif containing 24 -0.0149866
TYK2 tyrosine kinase 2 -0.0149441
USP42 ubiquitin specific peptidase 42 -0.014934
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0148963
RIOK3 RIO kinase 3 -0.0148637
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0148564
ATAD5 ATPase family, AAA domain containing 5 -0.0148453
SCARB1 scavenger receptor class B, member 1 -0.0148444
SNAP23 synaptosomal-associated protein, 23kDa -0.0147951
ILF3 interleukin enhancer binding factor 3, 90kDa -0.0147329
OSBPL9 oxysterol binding protein-like 9 -0.0147016
LONRF2 LON peptidase N-terminal domain and ring finger 2 -0.0146764
SERBP1 SERPINE1 mRNA binding protein 1 -0.014643
CDK12 cyclin-dependent kinase 12 -0.0146179
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0146001
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0145832
H2BC8 H2B clustered histone 8 -0.0145624
RSRP1 arginine/serine-rich protein 1 -0.0145536
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0145434
PDCD10 programmed cell death 10 -0.014523
FNBP1 formin binding protein 1 -0.0145069
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0144643
JAK1 Janus kinase 1 -0.0144509
BLTP3B bridge-like lipid transfer protein family member 3B -0.014416
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.0143799
AHCYL1 adenosylhomocysteinase-like 1 -0.014377
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0143672
L2HGDH L-2-hydroxyglutarate dehydrogenase -0.0143508
RAP1B RAP1B, member of RAS oncogene family -0.0142932
CPEB3 cytoplasmic polyadenylation element binding protein 3 -0.0142624
TRAPPC10 trafficking protein particle complex 10 -0.0142554
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0142469
RTN4 reticulon 4 -0.0142442
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.014233
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -0.0142169
GDA guanine deaminase -0.0142086
NAP1L1 nucleosome assembly protein 1-like 1 -0.0142004
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.0141797
ENSA endosulfine alpha -0.0141783
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0141742
HILPDA hypoxia inducible lipid droplet-associated -0.0141654
DCAF1 DDB1 and CUL4 associated factor 1 -0.0141577
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0141544
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0141484
ARG2 arginase 2 -0.0141179
GLRX3 glutaredoxin 3 -0.0140977
ZNF175 zinc finger protein 175 -0.0140929
NCALD neurocalcin delta -0.0140607
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -0.0140443
KIDINS220 kinase D-interacting substrate, 220kDa -0.0140306
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.014022
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0140106
ARHGAP24 Rho GTPase activating protein 24 -0.0140025
THRB thyroid hormone receptor, beta -0.0140003
TCOF1 Treacher Collins-Franceschetti syndrome 1 -0.0139877
ZNF592 zinc finger protein 592 -0.0139851
NDRG1 N-myc downstream regulated 1 -0.0139814
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0139475
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -0.013902
MPZL1 myelin protein zero-like 1 -0.0138909
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.0138869
KIAA1958 KIAA1958 -0.0138817
MED13 mediator complex subunit 13 -0.0138788
GFOD2 glucose-fructose oxidoreductase domain containing 2 -0.0138635
NUP107 nucleoporin 107kDa -0.0138521
ASXL1 additional sex combs like transcriptional regulator 1 -0.0138301
H2BC11 H2B clustered histone 11 -0.0138297
PRC1 protein regulator of cytokinesis 1 -0.0138253
COASY CoA synthase -0.0138243
SMAD3 SMAD family member 3 -0.0137605
KYAT1 kynurenine aminotransferase 1 -0.0137511
DNAH14 dynein, axonemal, heavy chain 14 -0.0137113
ADCY7 adenylate cyclase 7 -0.0137095
MLXIP MLX interacting protein -0.0136901
CDC25C cell division cycle 25C -0.0136714
RSL1D1 ribosomal L1 domain containing 1 -0.01367
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0136629
RFC2 replication factor C (activator 1) 2, 40kDa -0.0136463
FOXJ3 forkhead box J3 -0.0136307
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0135826
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0135722
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0135598
FLT1 fms-related tyrosine kinase 1 -0.0134939
SETD5 SET domain containing 5 -0.0134379
TMED5 transmembrane emp24 protein transport domain containing 5 -0.0134237
CHD4 chromodomain helicase DNA binding protein 4 -0.0133982
DNAH8 dynein, axonemal, heavy chain 8 -0.0133892
FAM222B family with sequence similarity 222, member B -0.0133836
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -0.0133666
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.013355
SCAI suppressor of cancer cell invasion -0.0133516
SEC63 SEC63 homolog (S. cerevisiae) -0.0133488
BAIAP2 BAI1-associated protein 2 -0.0133379
ADD3 adducin 3 (gamma) -0.0133357
BMAL2 basic helix-loop-helix ARNT like 2 -0.0133092
TEC tec protein tyrosine kinase -0.0132667
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0132538
SERF2 small EDRK-rich factor 2 -0.0131983
H2AZ2 H2A.Z variant histone 2 -0.0131983
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -0.0131915
GSR glutathione reductase -0.0131823
NRDC nardilysin convertase -0.0131675
MSMO1 methylsterol monooxygenase 1 -0.013164
MTCL1 microtubule crosslinking factor 1 -0.0131179
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -0.0131168
RPL34 ribosomal protein L34 -0.0131078
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -0.0130844
PNPLA8 patatin-like phospholipase domain containing 8 -0.013082
METTL16 methyltransferase like 16 -0.0130722
RPL22 ribosomal protein L22 -0.0130465
TRIM27 tripartite motif containing 27 -0.0130204
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.0130113
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0130061
TNRC6A trinucleotide repeat containing 6A -0.0129974
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0129651
WDR45 WD repeat domain 45 -0.0129128
RAP1A RAP1A, member of RAS oncogene family -0.0129092
SYNJ2 synaptojanin 2 -0.0129073
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0129065
SRPK2 SRSF protein kinase 2 -0.0129064
GSPT1 G1 to S phase transition 1 -0.0128917
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0128459
SEC24B SEC24 family member B -0.0128438
RAD23B RAD23 homolog B (S. cerevisiae) -0.0128242
FRRS1 ferric-chelate reductase 1 -0.0128
POM121 POM121 transmembrane nucleoporin -0.0127828
XPO5 exportin 5 -0.0127481
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -0.0127184
RNASEH1 ribonuclease H1 -0.0127131
SUSD6 sushi domain containing 6 -0.0126923
USP48 ubiquitin specific peptidase 48 -0.0126857
CLEC16A C-type lectin domain family 16, member A -0.0126561
ARF4 ADP-ribosylation factor 4 -0.0126417
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0126354
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.0126323
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.012629
VEGFA vascular endothelial growth factor A -0.0126248
CRPPA CDP-L-ribitol pyrophosphorylase A -0.012601
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -0.0125805
FLNC filamin C, gamma -0.012557
EPHB6 EPH receptor B6 -0.0125381
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0124979
APOC1 apolipoprotein C-I -0.0124833
C1ORF159 chromosome 1 open reading frame 159 -0.012478
ORC4 origin recognition complex, subunit 4 -0.0124406
ASL argininosuccinate lyase -0.0124289
RHD Rh blood group, D antigen -0.012419
COL6A5 collagen, type VI, alpha 5 -0.0123772
BLZF1 basic leucine zipper nuclear factor 1 -0.0123336
BRD4 bromodomain containing 4 -0.0123278
DCAF16 DDB1 and CUL4 associated factor 16 -0.0123079
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -0.0123045
LEPROT leptin receptor overlapping transcript -0.0122933
RSF1 remodeling and spacing factor 1 -0.0122584
PRAME preferentially expressed antigen in melanoma -0.0122436
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.0122309
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.0122247
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -0.0122198
ING3 inhibitor of growth family, member 3 -0.0122152
ZNF124 zinc finger protein 124 -0.0122135
DCHS2 dachsous cadherin-related 2 -0.0122105
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -0.0122007
ANAPC5 anaphase promoting complex subunit 5 -0.0121809
YY1AP1 YY1 associated protein 1 -0.0121753
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 -0.012172
MRPS27 mitochondrial ribosomal protein S27 -0.012162
CD46 CD46 molecule, complement regulatory protein -0.0121567
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -0.012138
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0121285
DOCK8 dedicator of cytokinesis 8 -0.0120995
OLA1 Obg-like ATPase 1 -0.0120916
MEF2D myocyte enhancer factor 2D -0.0120827
RIOK1 RIO kinase 1 -0.0120823
CPPED1 calcineurin-like phosphoesterase domain containing 1 -0.0120684
SMC4 structural maintenance of chromosomes 4 -0.0120512
PDE4A phosphodiesterase 4A, cAMP-specific -0.0120221
RPS20 ribosomal protein S20 -0.0120153
ZNF804A zinc finger protein 804A -0.0120034
LIN54 lin-54 DREAM MuvB core complex component -0.0119845
DHCR7 7-dehydrocholesterol reductase -0.0119817
SMAGP small cell adhesion glycoprotein -0.0119708
AGPS alkylglycerone phosphate synthase -0.0119592
SDCCAG8 serologically defined colon cancer antigen 8 -0.0119576
TMEM50A transmembrane protein 50A -0.0119449