K562_SNS-314 Mesylate_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SNS-314 Mesylate 100nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_SNS-314 Mesylate_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0913888
MUSK muscle, skeletal, receptor tyrosine kinase 0.0907772
NBAS neuroblastoma amplified sequence 0.075253
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0747335
FGF13 fibroblast growth factor 13 0.0686029
GOLGA4 golgin A4 0.0664187
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0661586
EPB41 erythrocyte membrane protein band 4.1 0.0652291
RPLP1 ribosomal protein, large, P1 0.0645969
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0632765
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.063155
ANK1 ankyrin 1, erythrocytic 0.0628557
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0594358
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0581076
CPED1 cadherin-like and PC-esterase domain containing 1 0.0531116
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0527911
ELOVL6 ELOVL fatty acid elongase 6 0.0526033
PRELID2 PRELI domain containing 2 0.0521421
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0508462
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0487845
INVS inversin 0.0483978
CDK6 cyclin-dependent kinase 6 0.0482184
MTDH metadherin 0.047522
LOC112694756 uncharaterized LOC112694756 0.0473998
ZFPM2 zinc finger protein, FOG family member 2 0.0465721
ZCCHC7 zinc finger, CCHC domain containing 7 0.046253
IARS1 isoleucyl-tRNA synthetase 1 0.0462175
ERBIN erbb2 interacting protein 0.0460232
HMBOX1 homeobox containing 1 0.0457104
PICALM phosphatidylinositol binding clathrin assembly protein 0.0454307
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0441758
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0440088
TMEM131L transmembrane 131 like 0.0437109
SETD5 SET domain containing 5 0.0434909
RABGAP1L RAB GTPase activating protein 1-like 0.0433884
CCND3 cyclin D3 0.0421599
RSRP1 arginine/serine-rich protein 1 0.0420906
LDHA lactate dehydrogenase A 0.041839
CCDC91 coiled-coil domain containing 91 0.0416046
RLF rearranged L-myc fusion 0.0414996
SLAIN2 SLAIN motif family, member 2 0.0412417
CUX1 cut-like homeobox 1 0.0409327
PDIA3 protein disulfide isomerase family A, member 3 0.0407485
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.0407062
NCOA1 nuclear receptor coactivator 1 0.0405681
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.0404152
CEP350 centrosomal protein 350kDa 0.0403346
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0402658
USP34 ubiquitin specific peptidase 34 0.039906
TBL1X transducin (beta)-like 1X-linked 0.0398977
STRBP spermatid perinuclear RNA binding protein 0.039725
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0393616
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0392981
OSBPL9 oxysterol binding protein-like 9 0.0390049
FBXO42 F-box protein 42 0.0389497
THOC2 THO complex 2 0.0389024
FBXO28 F-box protein 28 0.0388263
NMU neuromedin U 0.0385706
COPA coatomer protein complex, subunit alpha 0.0385644
SEPTIN6 septin 6 0.0384243
ABHD18 abhydrolase domain containing 18 0.0380156
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.0378197
MBNL1 muscleblind-like splicing regulator 1 0.037726
PHF14 PHD finger protein 14 0.0376909
UNK unkempt family zinc finger 0.0374671
GDNF glial cell derived neurotrophic factor 0.0372314
C17ORF99 chromosome 17 open reading frame 99 0.0370304
CENPF centromere protein F, 350/400kDa 0.0368286
LIMS1 LIM and senescent cell antigen-like domains 1 0.0365046
SIK3 SIK family kinase 3 0.0364614
NSD3 nuclear receptor binding SET domain protein 3 0.0364351
ASXL2 additional sex combs like transcriptional regulator 2 0.0363855
CAB39 calcium binding protein 39 0.0361995
TFRC transferrin receptor 0.0359953
DNM2 dynamin 2 0.0359895
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0357095
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.035589
GSE1 Gse1 coiled-coil protein 0.0353392
PEAK1 pseudopodium-enriched atypical kinase 1 0.0351617
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0350843
KDM4C lysine (K)-specific demethylase 4C 0.0349094
OGA O-GlcNAcase 0.0346971
TRIM33 tripartite motif containing 33 0.0346703
KLHL20 kelch-like family member 20 0.0342297
PCNX4 pecanex 4 0.0341932
MEIOB meiosis specific with OB domains 0.0339834
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.0339352
SATB2 SATB homeobox 2 0.03366
SPG11 spastic paraplegia 11 (autosomal recessive) 0.0334339
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0332891
RAB1A RAB1A, member RAS oncogene family 0.0328016
TUSC3 tumor suppressor candidate 3 0.0327105
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0326958
COP1 COP1 E3 ubiquitin ligase 0.032556
TTC28 tetratricopeptide repeat domain 28 0.0324829
MTX2 metaxin 2 0.0324698
CRPPA CDP-L-ribitol pyrophosphorylase A 0.0323087
TMEM135 transmembrane protein 135 0.0321315
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 0.0320785
NFIA nuclear factor I/A 0.0320045
LATS1 large tumor suppressor kinase 1 0.0319363
XPO1 exportin 1 0.0318236
EPS15 epidermal growth factor receptor pathway substrate 15 0.031754
LMNA lamin A/C 0.0316733
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.0316492
RAD51B RAD51 paralog B 0.031636
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0315152
DMD dystrophin 0.0314454
UBE3D ubiquitin protein ligase E3D 0.0313272
SENP6 SUMO1/sentrin specific peptidase 6 0.0313038
NOL9 nucleolar protein 9 0.0309204
CAMKMT calmodulin-lysine N-methyltransferase 0.030789
RNF38 ring finger protein 38 0.0307788
CDC73 cell division cycle 73 0.0307361
CLEC16A C-type lectin domain family 16, member A 0.0307188
FBXL20 F-box and leucine-rich repeat protein 20 0.030606
TGFB1 transforming growth factor, beta 1 0.0305102
UBA2 ubiquitin-like modifier activating enzyme 2 0.0305068
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0304653
MARCHF3 membrane associated ring-CH-type finger 3 0.0304617
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0303706
PHKB phosphorylase kinase, beta 0.0303612
ADAM17 ADAM metallopeptidase domain 17 0.0303407
PPT1 palmitoyl-protein thioesterase 1 0.0301142
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0300592
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.0299255
CAMTA1 calmodulin binding transcription activator 1 0.0299172
E2F3 E2F transcription factor 3 0.0296474
SIRAL2 SIR2 antiphage like 2 0.0296436
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0296021
CCNI cyclin I 0.0296019
TASOR2 transcription activation suppressor family member 2 0.0295717
PITRM1 pitrilysin metallopeptidase 1 0.0295299
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0294956
PRPF38B pre-mRNA processing factor 38B 0.0294221
PTPRB protein tyrosine phosphatase, receptor type, B 0.0294217
FNBP1 formin binding protein 1 0.0293911
ZNF124 zinc finger protein 124 0.0293407
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0291307
CALR calreticulin 0.0289731
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0288297
MBNL2 muscleblind-like splicing regulator 2 0.0287833
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0287571
TMEM120B transmembrane protein 120B 0.0285774
ATF6 activating transcription factor 6 0.0282948
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0282633
RACK1 receptor for activated C kinase 1 0.0281371
THRB thyroid hormone receptor, beta 0.0280906
CANX calnexin 0.0280842
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.0279297
NUP214 nucleoporin 214kDa 0.027772
ATG10 autophagy related 10 0.0277257
ARHGAP12 Rho GTPase activating protein 12 0.0277192
NSUN6 NOP2/Sun domain family, member 6 0.0277177
CERS6 ceramide synthase 6 0.0276681
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0275434
MBTD1 mbt domain containing 1 0.0275269
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0274833
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0274355
CNKSR3 CNKSR family member 3 0.0274068
PCDH9 protocadherin 9 0.0273283
COMMD1 copper metabolism (Murr1) domain containing 1 0.0272616
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0272229
DYNC2I1 dynein 2 intermediate chain 1 0.0271515
INTS10 integrator complex subunit 10 0.0271299
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0271112
USP22 ubiquitin specific peptidase 22 0.0271042
MECR mitochondrial trans-2-enoyl-CoA reductase 0.027056
ZNF800 zinc finger protein 800 0.0270445
AMBRA1 autophagy/beclin-1 regulator 1 0.0270374
LDAH lipid droplet associated hydrolase 0.0269561
CDYL chromodomain protein, Y-like 0.0268152
PTPN7 protein tyrosine phosphatase, non-receptor type 7 0.0266669
SERP1 stress-associated endoplasmic reticulum protein 1 0.0265677
RHOBTB3 Rho-related BTB domain containing 3 0.0265015
DHDDS dehydrodolichyl diphosphate synthase 0.0264359
CSDE1 cold shock domain containing E1, RNA-binding 0.0264193
RORA RAR-related orphan receptor A 0.0264026
FRRS1 ferric-chelate reductase 1 0.026278
FAM120B family with sequence similarity 120B 0.0262521
NF1 neurofibromin 1 0.0262467
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.0259962
FER fer (fps/fes related) tyrosine kinase 0.0259843
FAM117A family with sequence similarity 117, member A 0.0259189
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 0.0259158
STAT5B signal transducer and activator of transcription 5B 0.0258787
AFG2A AFG2 AAA ATPase homolog A 0.0258513
HDAC8 histone deacetylase 8 0.0258396
MAU2 MAU2 sister chromatid cohesion factor 0.0258301
NUDCD3 NudC domain containing 3 0.0257932
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0257853
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.025658
AHCYL2 adenosylhomocysteinase-like 2 0.0256046
PLIN4 perilipin 4 0.0255457
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.025461
OSBPL8 oxysterol binding protein-like 8 0.0254202
COPB1 coatomer protein complex, subunit beta 1 0.0253997
FAM13A family with sequence similarity 13, member A 0.0253453
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0253451
XPO7 exportin 7 0.0252516
EGLN1 egl-9 family hypoxia-inducible factor 1 0.025126
MAGT1 magnesium transporter 1 0.0250976
ESYT2 extended synaptotagmin-like protein 2 0.0250603
DENND4C DENN/MADD domain containing 4C 0.0250315
CLCN3 chloride channel, voltage-sensitive 3 0.0249363
WDR12 WD repeat domain 12 0.0247062
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0246778
CEP170 centrosomal protein 170kDa 0.0244641
UBE2B ubiquitin-conjugating enzyme E2B 0.0244163
NEK1 NIMA-related kinase 1 0.0243318
TMC6 transmembrane channel-like 6 0.0242631
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0241076
RPLP0 ribosomal protein, large, P0 0.023912
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0238882
ADAR adenosine deaminase, RNA-specific 0.0238361
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0237014
ZNF207 zinc finger protein 207 0.0236891
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0236417
NCOA6 nuclear receptor coactivator 6 0.0235764
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0234499
TMEM165 transmembrane protein 165 0.0234124
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 0.0234064
CSPP1 centrosome and spindle pole associated protein 1 0.023384
RDX radixin 0.0232711
CHPT1 choline phosphotransferase 1 0.02326
KIAA0319L KIAA0319-like 0.0231959
TRIT1 tRNA isopentenyltransferase 1 0.0230813
TMEM41A transmembrane protein 41A 0.0230513
TRRAP transformation/transcription domain-associated protein 0.023034
KIAA1958 KIAA1958 0.0230198
HDGF hepatoma-derived growth factor 0.02297
NCEH1 neutral cholesterol ester hydrolase 1 0.0229634
GON4L gon-4-like (C. elegans) 0.0229586
RPL37 ribosomal protein L37 0.0229324
DOCK9 dedicator of cytokinesis 9 0.0228558
SEPTIN11 septin 11 0.0228518
GPBP1 GC-rich promoter binding protein 1 0.0228348
PNISR PNN-interacting serine/arginine-rich protein 0.0227743
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0227264
XPR1 xenotropic and polytropic retrovirus receptor 1 0.0227241
HEPH hephaestin 0.0226761
SRBD1 S1 RNA binding domain 1 0.0226717
DNAH14 dynein, axonemal, heavy chain 14 0.0226571
KDM4B lysine (K)-specific demethylase 4B 0.0226304
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.022555
UBE2K ubiquitin-conjugating enzyme E2K 0.0225456
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.0225238
TMOD1 tropomodulin 1 0.0224874
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.0224143
TCP1 t-complex 1 0.0223581
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0223471
GTF2B general transcription factor IIB 0.0223346
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0223339
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.022323
SACK1A scaffolding CK1 anchoring protein A 0.0223101
DMXL1 Dmx-like 1 0.0222231
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.0221864
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0221723
PUS7 pseudouridylate synthase 7 (putative) 0.0221488
BCL6 B-cell CLL/lymphoma 6 0.0221239
SORT1 sortilin 1 0.022099
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0220629
LAPTM4B lysosomal protein transmembrane 4 beta 0.0220125
OCIAD1 OCIA domain containing 1 0.0219845
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0219809
LMAN2L lectin, mannose-binding 2-like 0.0219291
ANAPC10 anaphase promoting complex subunit 10 0.0219289
ABHD5 abhydrolase domain containing 5 0.0219077
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0219064
GOLPH3L golgi phosphoprotein 3-like 0.0218891
MRPS25 mitochondrial ribosomal protein S25 0.0218739
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 0.0217509
N4BP2L2 NEDD4 binding protein 2-like 2 0.0217381
H1-10 H1.10 linker histone 0.0217072
LIN28B lin-28 homolog B (C. elegans) 0.0216209
LARP4B La ribonucleoprotein domain family, member 4B 0.0216094
KMT2E lysine (K)-specific methyltransferase 2E 0.0215803
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.0215274
HEATR5B HEAT repeat containing 5B 0.0215191
UIMC1 ubiquitin interaction motif containing 1 0.0215122
PDZD8 PDZ domain containing 8 0.0214367
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0214086
PIAS1 protein inhibitor of activated STAT, 1 0.0214054
TOP2B topoisomerase (DNA) II beta 180kDa 0.0213826
RNFT2 ring finger protein, transmembrane 2 0.0213334
XXYLT1 xyloside xylosyltransferase 1 0.0212924
ZNF791 zinc finger protein 791 0.0211776
ATM ATM serine/threonine kinase 0.0211767
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0211573
HDAC7 histone deacetylase 7 0.021135
REXO5 RNA exonuclease 5 0.0210762
LGALS8 lectin, galactoside-binding, soluble, 8 0.0210431
ZNF782 zinc finger protein 782 0.0210398
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.020972
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0208926
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0208161
RPTOR regulatory associated protein of MTOR, complex 1 0.0208037
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.0207844
STX12 syntaxin 12 0.0207668
MYLIP myosin regulatory light chain interacting protein 0.0207097
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 0.0206315
ADGRB3 adhesion G protein-coupled receptor B3 0.0205589
CELF1 CUGBP, Elav-like family member 1 0.0205412
MIPEP mitochondrial intermediate peptidase 0.0205392
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0205115
EXOC6 exocyst complex component 6 0.0204571
CLINT1 clathrin interactor 1 0.020425
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0204163
CIZ1 CDKN1A interacting zinc finger protein 1 0.020405
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0203837
BMAL2 basic helix-loop-helix ARNT like 2 0.0203766
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.0203485
MTA3 metastasis associated 1 family, member 3 0.0203365
PTK2 protein tyrosine kinase 2 0.0203359
FADS2 fatty acid desaturase 2 0.0203067
ZZZ3 zinc finger, ZZ-type containing 3 0.0202933
NOSTRIN nitric oxide synthase trafficking 0.0202881
ZRANB2 zinc finger, RAN-binding domain containing 2 0.0202703
AVL9 AVL9 homolog (S. cerevisiase) 0.0202418
PTPRH protein tyrosine phosphatase, receptor type, H 0.0202413
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.0202206
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.0202191
TBC1D22B TBC1 domain family, member 22B 0.0201992
SNX8 sorting nexin 8 0.020178
RPL32 ribosomal protein L32 0.0201726
KLHL8 kelch-like family member 8 0.0201175
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.0200895
MAPK14 mitogen-activated protein kinase 14 0.0200763
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.0200537
USP37 ubiquitin specific peptidase 37 0.0199937
TUBB6 tubulin, beta 6 class V 0.0199705
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.0199115
EIF3B eukaryotic translation initiation factor 3, subunit B 0.0198316
SFPQ splicing factor proline/glutamine-rich 0.0197443
MYH10 myosin, heavy chain 10, non-muscle 0.0197196
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0196996
WDR20 WD repeat domain 20 0.0196583
WDR43 WD repeat domain 43 0.0196291
HOOK2 hook microtubule-tethering protein 2 0.0196021
SLC35D4 solute carrier family 35 member D4 0.0195694
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0195212
VIRMA vir like m6A methyltransferase associated 0.0194873
FAM193B family with sequence similarity 193, member B 0.0194504
SEPTIN7 septin 7 0.01944
PRRC2A proline-rich coiled-coil 2A 0.0194328
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0193846
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0193183
CTSC cathepsin C 0.0193031
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0.0192828
SLC43A3 solute carrier family 43, member 3 0.019276
MED13L mediator complex subunit 13-like 0.0192304
IGSF1 immunoglobulin superfamily, member 1 0.0192099
RB1CC1 RB1-inducible coiled-coil 1 0.0191816
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.0190957
DRAM2 DNA-damage regulated autophagy modulator 2 0.0190865
UNC13D unc-13 homolog D (C. elegans) 0.0190842
RPL7L1 ribosomal protein L7-like 1 0.0190812
ATOSA atos homolog A 0.0190776
ANKRD13C ankyrin repeat domain 13C 0.019069
SQSTM1 sequestosome 1 0.0190408
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.0190145
PPP6R1 protein phosphatase 6, regulatory subunit 1 0.0189789
TMEM263 transmembrane protein 263 0.0189697
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0189391
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.0188917
INTS6L integrator complex subunit 6 like 0.0188899
NFE2L2 nuclear factor, erythroid 2-like 2 0.018865
IMMT inner membrane protein, mitochondrial 0.0188484
USP12 ubiquitin specific peptidase 12 0.0187972
CFLAR CASP8 and FADD-like apoptosis regulator 0.0187801
UVRAG UV radiation resistance associated 0.01875
NUMA1 nuclear mitotic apparatus protein 1 0.0186981
UBAC1 UBA domain containing 1 0.0186762
NPEPPS aminopeptidase puromycin sensitive 0.0185839
CD58 CD58 molecule 0.018577
LCORL ligand dependent nuclear receptor corepressor-like 0.0185678
CD81 CD81 molecule 0.018555
REEP5 receptor accessory protein 5 0.0185488
EEF2 eukaryotic translation elongation factor 2 0.0185456
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 0.0185318
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0184789
STEAP1B STEAP family member 1B 0.0184716
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.018447
NCAM2 neural cell adhesion molecule 2 0.0183843
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.0183799
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.0183791
BCLAF1 BCL2-associated transcription factor 1 0.0183748
SCAF11 SR-related CTD-associated factor 11 0.0183481
WDR45 WD repeat domain 45 0.0183068
UBE3C ubiquitin protein ligase E3C 0.0182992
ICE2 interactor of little elongation complex ELL subunit 2 0.0182718
UBTF upstream binding transcription factor, RNA polymerase I 0.0182603
AKAP8L A kinase (PRKA) anchor protein 8-like 0.0182598
IGF2R insulin-like growth factor 2 receptor 0.0182111
MAP2K1 mitogen-activated protein kinase kinase 1 0.0181661
NAT10 N-acetyltransferase 10 (GCN5-related) 0.0181412
FXR1 fragile X mental retardation, autosomal homolog 1 0.0181045
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.0180753
RPL35 ribosomal protein L35 0.0180403
RREB1 ras responsive element binding protein 1 0.0180242
NT5DC2 5'-nucleotidase domain containing 2 0.0180136
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 0.0180068
RPL39 ribosomal protein L39 0.0180051
ABHD2 abhydrolase domain containing 2 0.0179958
OXR1 oxidation resistance 1 0.0179918
ZNF12 zinc finger protein 12 0.0179318
TPX2 TPX2, microtubule-associated 0.0179286
RANBP9 RAN binding protein 9 0.017921
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0179194
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 0.0179145
ELP3 elongator acetyltransferase complex subunit 3 0.0179028
ZEB2 zinc finger E-box binding homeobox 2 0.0178767
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.017857
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0178435
BST2 bone marrow stromal cell antigen 2 0.0178101
ADGRE5 adhesion G protein-coupled receptor E5 0.017766
TOGARAM1 TOG array regulator of axonemal microtubules 1 0.017765
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0177062
PCCB propionyl CoA carboxylase, beta polypeptide 0.0176724
SEC11A SEC11 homolog A (S. cerevisiae) 0.0176636
PTCD3 pentatricopeptide repeat domain 3 0.0176586
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.0176564
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.0176435
DROSHA drosha, ribonuclease type III 0.0176362
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0176307
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.017615
IP6K1 inositol hexakisphosphate kinase 1 0.0176001
RPS3 ribosomal protein S3 0.017597
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.0175651
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0175271
DHCR24 24-dehydrocholesterol reductase 0.0175155
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.0175082
ZBTB20 zinc finger and BTB domain containing 20 0.0175043
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0174629
ANAPC16 anaphase promoting complex subunit 16 0.0174458
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.017417
XRN1 5'-3' exoribonuclease 1 0.0173909
RCSD1 RCSD domain containing 1 0.0173689
EXPH5 exophilin 5 0.017351
TMEM116 transmembrane protein 116 0.017345
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0173095
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.0172713
CREB5 cAMP responsive element binding protein 5 0.0172448
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.0172342
TCF20 transcription factor 20 (AR1) 0.0172199
TGFBR3 transforming growth factor, beta receptor III 0.0172179
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.0171935
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.0171352
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.0171337
ZMYM4 zinc finger, MYM-type 4 0.017127
FBXO34 F-box protein 34 0.0171108
USP42 ubiquitin specific peptidase 42 0.0170974
MRPL1 mitochondrial ribosomal protein L1 0.0170715
CNTN5 contactin 5 0.0170696
CUL5 cullin 5 0.0170688
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 0.0170658
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 0.0170613
SMAD3 SMAD family member 3 0.0170591
KIF2A kinesin heavy chain member 2A 0.0170476
AP3M1 adaptor-related protein complex 3, mu 1 subunit 0.0169976
RPL5 ribosomal protein L5 0.0169972
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.0169834
ZMYND8 zinc finger, MYND-type containing 8 0.0169798
H2AC6 H2A clustered histone 6 0.0169761
ZBTB35 zinc finger and BTB domain containing 35 0.0169526
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.0169372
TM2D1 TM2 domain containing 1 0.0169176
CCDC32 coiled-coil domain containing 32 0.0168946
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.0168746
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 0.0168727
SRSF11 serine/arginine-rich splicing factor 11 0.0168564
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.016855
STRIP2 striatin interacting protein 2 0.0168327
TBC1D32 TBC1 domain family, member 32 0.0168301
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.0168252
SUMF1 sulfatase modifying factor 1 0.0168249
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.016816
NEK7 NIMA-related kinase 7 0.0168011
PPP6C protein phosphatase 6, catalytic subunit 0.0167857
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0167791
RBM39 RNA binding motif protein 39 0.0167538
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0167126
LARP1B La ribonucleoprotein domain family, member 1B 0.0166351
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0166311
CUL4B cullin 4B 0.0166154
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 0.0165555
ACSL4 acyl-CoA synthetase long-chain family member 4 0.016517
MDN1 MDN1, midasin homolog (yeast) 0.0165043
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.0164908
ZNF407 zinc finger protein 407 0.0164906
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.0164698
TPD52L1 tumor protein D52-like 1 0.0164653
DLAT dihydrolipoamide S-acetyltransferase 0.0164361
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0164155
TSLIG1 tRNA splicing ligase complex subunit 1 0.0164094
SARAF store-operated calcium entry-associated regulatory factor 0.0163999
OXNAD1 oxidoreductase NAD-binding domain containing 1 0.0163963
FNIP1 folliculin interacting protein 1 0.0163907
ATAD2 ATPase family, AAA domain containing 2 0.0163594
FANCL Fanconi anemia, complementation group L 0.0163557

decreased expression

Symbol Name Standardized Value
ADGRV1 adhesion G protein-coupled receptor V1 -0.129814
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0785707
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0706809
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0672554
HP1BP3 heterochromatin protein 1, binding protein 3 -0.063667
ARHGAP21 Rho GTPase activating protein 21 -0.0600678
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0591113
RPS5 ribosomal protein S5 -0.0585224
ENO1 enolase 1, (alpha) -0.0556723
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.049267
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0473869
RELN reelin -0.0473543
MAML2 mastermind-like 2 (Drosophila) -0.0472207
KRT8 keratin 8, type II -0.0471969
TUBB tubulin, beta class I -0.0468721
ACTN4 actinin, alpha 4 -0.045023
GPC5 glypican 5 -0.0440226
FBXL13 F-box and leucine-rich repeat protein 13 -0.0429138
RNF216 ring finger protein 216 -0.0422451
KPNB1 karyopherin (importin) beta 1 -0.0419423
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0415045
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.040784
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0393586
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0384004
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0383984
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0381363
UBE4B ubiquitination factor E4B -0.0379497
USP32 ubiquitin specific peptidase 32 -0.0375974
VCL vinculin -0.0372002
PRKCA protein kinase C, alpha -0.0371381
SETD2 SET domain containing 2 -0.0370757
ANTXR2 anthrax toxin receptor 2 -0.0367304
SGMS1 sphingomyelin synthase 1 -0.0365506
AGO3 argonaute RISC catalytic component 3 -0.0363246
MYO1D myosin ID -0.0362316
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0358621
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.035785
NBEAL1 neurobeachin-like 1 -0.0356938
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0354064
PBRM1 polybromo 1 -0.035225
GPHN gephyrin -0.0352099
DCAF10 DDB1 and CUL4 associated factor 10 -0.0349367
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0348516
LRP12 low density lipoprotein receptor-related protein 12 -0.0347875
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0340223
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.0339034
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0336061
CHD4 chromodomain helicase DNA binding protein 4 -0.0334264
ASPH aspartate beta-hydroxylase -0.03342
CFAP161 cilia and flagella associated protein 161 -0.0332772
CDK13 cyclin-dependent kinase 13 -0.0331453
POTEF POTE ankyrin domain family, member F -0.0328859
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.0318676
SLC19A1 solute carrier family 19 (folate transporter), member 1 -0.0317445
LTBP1 latent transforming growth factor beta binding protein 1 -0.0316437
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0316125
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0315225
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.0315165
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0313766
CENPE centromere protein E, 312kDa -0.0313305
NAV1 neuron navigator 1 -0.0312762
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.0311083
MCU mitochondrial calcium uniporter -0.0310561
WWOX WW domain containing oxidoreductase -0.0310469
IQGAP2 IQ motif containing GTPase activating protein 2 -0.0305541
CTBP2 C-terminal binding protein 2 -0.0305164
CALU calumenin -0.0303801
PHACTR4 phosphatase and actin regulator 4 -0.0303578
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.030277
NSD2 nuclear receptor binding SET domain protein 2 -0.0302004
ANKRD11 ankyrin repeat domain 11 -0.0301025
HPCAL1 hippocalcin-like 1 -0.0301015
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0297691
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.0297163
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0296878
ASXL1 additional sex combs like transcriptional regulator 1 -0.0296116
KDM2A lysine (K)-specific demethylase 2A -0.0295462
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0294826
GLUL glutamate-ammonia ligase -0.0293362
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0293016
MYO19 myosin XIX -0.02905
PUM3 pumilio RNA binding family member 3 -0.0287939
BRD4 bromodomain containing 4 -0.0286905
SRRM2 serine/arginine repetitive matrix 2 -0.0285733
PLCL1 phospholipase C-like 1 -0.0283694
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0283091
RPL19 ribosomal protein L19 -0.0281442
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0278844
KIF1B kinesin family member 1B -0.0278691
CLTC clathrin, heavy chain (Hc) -0.0278283
PRRC2C proline-rich coiled-coil 2C -0.0277043
TNPO1 transportin 1 -0.0276731
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0275804
ZFR zinc finger RNA binding protein -0.027485
MICU1 mitochondrial calcium uptake 1 -0.027315
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0273076
TUT4 terminal uridylyl transferase 4 -0.0272563
RPL37A ribosomal protein L37a -0.0272414
SETX senataxin -0.0272354
FOXP1 forkhead box P1 -0.027178
ADAM10 ADAM metallopeptidase domain 10 -0.0271558
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0270756
CREBBP CREB binding protein -0.0270243
CA8 carbonic anhydrase VIII -0.0270212
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0267766
TOX4 TOX high mobility group box family member 4 -0.0267416
SPAG9 sperm associated antigen 9 -0.026733
BIRC6 baculoviral IAP repeat containing 6 -0.0266865
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0265307
ETV6 ets variant 6 -0.0265048
RHOT1 ras homolog family member T1 -0.0264455
MED12 mediator complex subunit 12 -0.0261335
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0261116
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0258238
BRCA1 breast cancer 1, early onset -0.0256538
PARD3B par-3 family cell polarity regulator beta -0.0255353
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0254958
TGOLN2 trans-golgi network protein 2 -0.0254196
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0252777
SAFB scaffold attachment factor B -0.025265
SMYD3 SET and MYND domain containing 3 -0.0252154
RPS2 ribosomal protein S2 -0.0250576
SOGA1 suppressor of glucose, autophagy associated 1 -0.0247957
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.0247941
GATAD2A GATA zinc finger domain containing 2A -0.024743
LIMA1 LIM domain and actin binding 1 -0.0247285
RAP1B RAP1B, member of RAS oncogene family -0.0247146
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -0.0247028
FAM13B family with sequence similarity 13, member B -0.024662
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0246369
GATAD2B GATA zinc finger domain containing 2B -0.0245378
FHIT fragile histidine triad -0.0245003
RPN2 ribophorin II -0.0242939
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0242552
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0241141
NUP107 nucleoporin 107kDa -0.0240803
PLIN3 perilipin 3 -0.0240556
CENPC centromere protein C -0.0240539
KAT6B K(lysine) acetyltransferase 6B -0.0239176
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0238777
LTN1 listerin E3 ubiquitin protein ligase 1 -0.0237395
STAG2 stromal antigen 2 -0.0237354
CDCA2 cell division cycle associated 2 -0.0235989
ASF1B anti-silencing function 1B histone chaperone -0.0235978
ATF5 activating transcription factor 5 -0.0235513
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.0235311
FLNC filamin C, gamma -0.0235256
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0235008
DGCR8 DGCR8 microprocessor complex subunit -0.023457
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0233731
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0233692
LIN54 lin-54 DREAM MuvB core complex component -0.0233391
SH2B3 SH2B adaptor protein 3 -0.0232804
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0232328
MYO16 myosin XVI -0.0231227
SSH2 slingshot protein phosphatase 2 -0.023119
OSBPL3 oxysterol binding protein-like 3 -0.0230634
EIF5B eukaryotic translation initiation factor 5B -0.0229042
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0228988
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0227332
DLG1 discs, large homolog 1 (Drosophila) -0.0226534
HIC2 hypermethylated in cancer 2 -0.0223603
RFX7 regulatory factor X, 7 -0.0223269
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0223165
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.022279
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0222659
PPA1 pyrophosphatase (inorganic) 1 -0.0222622
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0222303
SIN3A SIN3 transcription regulator family member A -0.0222217
JAK1 Janus kinase 1 -0.0221836
GRB2 growth factor receptor-bound protein 2 -0.0220929
RNF130 ring finger protein 130 -0.0220697
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0219961
RUFY2 RUN and FYVE domain containing 2 -0.0219858
HMGA1 high mobility group AT-hook 1 -0.0219512
BICD1 bicaudal D homolog 1 (Drosophila) -0.0218945
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 -0.0218695
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0218406
AMOTL1 angiomotin like 1 -0.0217878
PPP5C protein phosphatase 5, catalytic subunit -0.021786
TYK2 tyrosine kinase 2 -0.021779
NT5C2 5'-nucleotidase, cytosolic II -0.0217569
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.0217114
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0216995
HBG2 hemoglobin, gamma G -0.0216853
SYNJ2 synaptojanin 2 -0.021664
BSG basigin (Ok blood group) -0.0216612
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0216386
EPN2 epsin 2 -0.0216006
JUP junction plakoglobin -0.0215697
POT1 protection of telomeres 1 -0.0215292
MAPK8 mitogen-activated protein kinase 8 -0.0215225
MBD5 methyl-CpG binding domain protein 5 -0.0215139
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -0.0215086
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0214795
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0214439
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0214403
JARID2 jumonji, AT rich interactive domain 2 -0.0213963
ARHGAP18 Rho GTPase activating protein 18 -0.0213111
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0213099
H3-3B H3.3 histone B -0.0213097
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0212204
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.0211805
SMAP1 small ArfGAP 1 -0.0211328
ZNF621 zinc finger protein 621 -0.0208977
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) -0.0208553
SARS2 seryl-tRNA synthetase 2, mitochondrial -0.0207681
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -0.0207583
SIL1 SIL1 nucleotide exchange factor -0.0207067
TPI1 triosephosphate isomerase 1 -0.0207032
NME7 NME/NM23 family member 7 -0.0205669
MTFR1 mitochondrial fission regulator 1 -0.0205325
PCBP2 poly(rC) binding protein 2 -0.0204856
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0204823
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0204428
MMS22L MMS22-like, DNA repair protein -0.0204415
CELF2 CUGBP, Elav-like family member 2 -0.0204059
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0203685
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0202968
PRKCSH protein kinase C substrate 80K-H -0.0202623
SIK2 salt-inducible kinase 2 -0.0202211
HIP1 huntingtin interacting protein 1 -0.0201809
NDE1 nudE neurodevelopment protein 1 -0.0201583
FNDC3B fibronectin type III domain containing 3B -0.0201453
TACC3 transforming, acidic coiled-coil containing protein 3 -0.0200632
SNAP29 synaptosomal-associated protein, 29kDa -0.0200201
CEP152 centrosomal protein 152kDa -0.0199985
ARL15 ADP-ribosylation factor-like 15 -0.0199913
TRAPPC9 trafficking protein particle complex 9 -0.0199838
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0199455
MARCHF6 membrane associated ring-CH-type finger 6 -0.0197524
DMAC2L distal membrane arm assembly component 2 like -0.0197234
FLNA filamin A, alpha -0.019703
HBZ hemoglobin, zeta -0.0195818
SKA2 spindle and kinetochore associated complex subunit 2 -0.0195403
FBXO46 F-box protein 46 -0.0194945
SMC4 structural maintenance of chromosomes 4 -0.0194917
AP2A1 adaptor-related protein complex 2, alpha 1 subunit -0.0194602
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -0.0194304
NALF1 NALCN channel auxiliary factor 1 -0.0194079
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0193916
KMT2C lysine (K)-specific methyltransferase 2C -0.019313
CD2AP CD2-associated protein -0.0193076
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.0192964
NRF1 nuclear respiratory factor 1 -0.0190981
CASS4 Cas scaffolding protein family member 4 -0.0190565
RNASE3 ribonuclease, RNase A family, 3 -0.0190029
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0189618
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -0.0189203
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0189123
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0188229
TPM4 tropomyosin 4 -0.0187538
GSK3B glycogen synthase kinase 3 beta -0.0186737
KLHDC10 kelch domain containing 10 -0.018645
GCLC glutamate-cysteine ligase, catalytic subunit -0.0186277
CARD8 caspase recruitment domain family, member 8 -0.0186142
CLIP1 CAP-GLY domain containing linker protein 1 -0.0185841
SRRM1 serine/arginine repetitive matrix 1 -0.0184746
USP48 ubiquitin specific peptidase 48 -0.0184607
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.0183627
USP24 ubiquitin specific peptidase 24 -0.0181504
TRIM37 tripartite motif containing 37 -0.0181403
CEP192 centrosomal protein 192kDa -0.0181398
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0180671
PTPRA protein tyrosine phosphatase, receptor type, A -0.0180529
GOLIM4 golgi integral membrane protein 4 -0.0180455
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0180202
ARL8B ADP-ribosylation factor-like 8B -0.0180055
RIPOR3 RIPOR family member 3 -0.0179772
C21ORF58 chromosome 21 open reading frame 58 -0.0179771
PEX26 peroxisomal biogenesis factor 26 -0.0179702
GSTP1 glutathione S-transferase pi 1 -0.0179523
ZBTB11 zinc finger and BTB domain containing 11 -0.0179094
HEATR1 HEAT repeat containing 1 -0.0178428
NUP153 nucleoporin 153kDa -0.0178178
ZSCAN5A zinc finger and SCAN domain containing 5A -0.0177821
ZNF280D zinc finger protein 280D -0.01776
PELI1 pellino E3 ubiquitin protein ligase 1 -0.017738
MCM10 minichromosome maintenance complex component 10 -0.0177226
FAM168A family with sequence similarity 168, member A -0.0176786
NLK nemo-like kinase -0.0176671
RPL3 ribosomal protein L3 -0.0176242
CD44 CD44 molecule (Indian blood group) -0.0176033
ETF1 eukaryotic translation termination factor 1 -0.0175752
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0175469
EIF1 eukaryotic translation initiation factor 1 -0.0175327
FANCC Fanconi anemia, complementation group C -0.0174956
MKI67 marker of proliferation Ki-67 -0.0174667
DOCK11 dedicator of cytokinesis 11 -0.0174663
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0174094
RRM1 ribonucleotide reductase M1 -0.0173782
LSG1 large 60S subunit nuclear export GTPase 1 -0.0172958
CCAR1 cell division cycle and apoptosis regulator 1 -0.017235
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0172011
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0171733
FAM222B family with sequence similarity 222, member B -0.0171075
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0170784
SLF2 SMC5-SMC6 complex localization factor 2 -0.01703
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.0170206
PXDN peroxidasin -0.0170104
CLASRP CLK4-associating serine/arginine rich protein -0.0169976
DAND5 DAN domain family member 5, BMP antagonist -0.0169481
MPHOSPH9 M-phase phosphoprotein 9 -0.0169384
CEP85L centrosomal protein 85kDa-like -0.0169362
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0169313
LPIN2 lipin 2 -0.0169222
CFAP44 cilia and flagella associated protein 44 -0.0169219
KPNA1 karyopherin alpha 1 (importin alpha 5) -0.0168947
ZC3H12C zinc finger CCCH-type containing 12C -0.0168634
RUNX1 runt-related transcription factor 1 -0.0168408
UBL4A ubiquitin-like 4A -0.0168192
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0167788
COTL1 coactosin-like F-actin binding protein 1 -0.0167697
SMAD5 SMAD family member 5 -0.0167314
NCKAP1 NCK-associated protein 1 -0.0167187
KAZN kazrin, periplakin interacting protein -0.0167185
EVL Enah/Vasp-like -0.0167016
SHTN1 shootin 1 -0.0166424
TUBA1B tubulin, alpha 1b -0.0165372
GANAB glucosidase, alpha; neutral AB -0.0165315
CDCA8 cell division cycle associated 8 -0.0165047
PTMA prothymosin, alpha -0.0164395
CNTNAP2 contactin associated protein-like 2 -0.0164337
CUL2 cullin 2 -0.0164329
CAPNS1 calpain, small subunit 1 -0.016381
TMEM87A transmembrane protein 87A -0.0163494
RPS11 ribosomal protein S11 -0.0163332
TAC4 tachykinin 4 (hemokinin) -0.0163016
RPS15 ribosomal protein S15 -0.0162855
NUP93 nucleoporin 93kDa -0.0162715
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -0.0162692
ACACA acetyl-CoA carboxylase alpha -0.0162606
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.0162526
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0161768
RPL18 ribosomal protein L18 -0.0161629
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.016162
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0161545
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0161499
GATA2 GATA binding protein 2 -0.0161414
BFAR bifunctional apoptosis regulator -0.016099
DRC8 dynein regulatory complex subunit 8 -0.0160526
HYOU1 hypoxia up-regulated 1 -0.0160502
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0160279
DAAM1 dishevelled associated activator of morphogenesis 1 -0.0159909
RAI14 retinoic acid induced 14 -0.0159881
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0159807
CLOCK clock circadian regulator -0.0159703
RPL36 ribosomal protein L36 -0.0159639
MED15 mediator complex subunit 15 -0.015903
DNA2 DNA replication helicase/nuclease 2 -0.0158912
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0158403
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -0.0158101
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.0157635
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0157578
RPL9 ribosomal protein L9 -0.0156974
TANGO2 transport and golgi organization 2 homolog (Drosophila) -0.0156835
ANGPT1 angiopoietin 1 -0.0156424
NUMB numb homolog (Drosophila) -0.0156226
GPATCH4 G patch domain containing 4 -0.0156085
DCAF5 DDB1 and CUL4 associated factor 5 -0.0155881
ANXA2 annexin A2 -0.0155215
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0154962
PDE4D phosphodiesterase 4D, cAMP-specific -0.0154927
HSPB1 heat shock 27kDa protein 1 -0.0154884
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.0154772
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -0.0154484
ATAD2B ATPase family, AAA domain containing 2B -0.0154422
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0154353
SCG3 secretogranin III -0.015403
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -0.0153999
LUC7L LUC7-like (S. cerevisiae) -0.015396
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -0.0153783
AATF apoptosis antagonizing transcription factor -0.0153506
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.015339
GLG1 golgi glycoprotein 1 -0.0153257
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0152753
TMEM50A transmembrane protein 50A -0.0152577
RBL1 retinoblastoma-like 1 -0.0152557
CCNY cyclin Y -0.0151439
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0151349
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.0151335
BLTP3A bridge-like lipid transfer protein family member 3A -0.0151062
REV1 REV1, polymerase (DNA directed) -0.0150997
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.0150971
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0150824
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0150679
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0150615
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0150564
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.0150122
CCDC47 coiled-coil domain containing 47 -0.0150059
YTHDC2 YTH domain containing 2 -0.0149704
MIA3 melanoma inhibitory activity family, member 3 -0.0149686
SMIM44 small integral membrane protein 44 -0.0149644
TMEM156 transmembrane protein 156 -0.0149285
CD59 CD59 molecule, complement regulatory protein -0.0149275
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -0.0149174
STON2 stonin 2 -0.0148974
WWC2 WW and C2 domain containing 2 -0.0148701
TBC1D2B TBC1 domain family, member 2B -0.014835
TNPO2 transportin 2 -0.0148307
GLRX3 glutaredoxin 3 -0.0148093
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.0147923
FOXK2 forkhead box K2 -0.0147487
RHEB Ras homolog enriched in brain -0.0146996
MRPS16 mitochondrial ribosomal protein S16 -0.0146968
PCM1 pericentriolar material 1 -0.0146928
H4C3 H4 clustered histone 3 -0.0146883
GINM1 glycoprotein integral membrane 1 -0.0146795
ENOSF1 enolase superfamily member 1 -0.0146624
YARS1 tyrosyl-tRNA synthetase 1 -0.0146615
SSR1 signal sequence receptor, alpha -0.0146576
SEC31A SEC31 homolog A (S. cerevisiae) -0.0146557
PKNOX1 PBX/knotted 1 homeobox 1 -0.0146375
DPP8 dipeptidyl-peptidase 8 -0.0146066
PDIA4 protein disulfide isomerase family A, member 4 -0.014599
PFDN1 prefoldin subunit 1 -0.0145619
HBS1L HBS1-like translational GTPase -0.0145465
KPNA3 karyopherin alpha 3 (importin alpha 4) -0.0145006
UBIAD1 UbiA prenyltransferase domain containing 1 -0.0144981
LMBR1 limb development membrane protein 1 -0.0144597
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -0.0144568
WDR26 WD repeat domain 26 -0.0144521
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0144404
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -0.0144375
HDGFL2 HDGF like 2 -0.0144215
EIF4E eukaryotic translation initiation factor 4E -0.0144105
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0144049
NCOA7 nuclear receptor coactivator 7 -0.0143928
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -0.0143892
ZC3H7B zinc finger CCCH-type containing 7B -0.0143672
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0143518
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -0.0143504
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -0.0143466
GIPC1 GIPC PDZ domain containing family, member 1 -0.0143464
RANBP3 RAN binding protein 3 -0.0143421
ATXN2L ataxin 2-like -0.0143412
VASP vasodilator-stimulated phosphoprotein -0.014328
KLHDC4 kelch domain containing 4 -0.0143265
CDC45 cell division cycle 45 -0.0143249
NEBL nebulette -0.0143198
MTM1 myotubularin 1 -0.0143099
CORO1C coronin, actin binding protein, 1C -0.0142795
KTN1 kinectin 1 (kinesin receptor) -0.0142381
ZNF804B zinc finger protein 804B -0.0142286
VKORC1 vitamin K epoxide reductase complex, subunit 1 -0.0142242
CFH complement factor H -0.0142157
BHLHE40 basic helix-loop-helix family, member e40 -0.0142135
CKAP2L cytoskeleton associated protein 2-like -0.0141914
PFN1 profilin 1 -0.0141909
DGCR2 DiGeorge syndrome critical region gene 2 -0.014189
TCERG1 transcription elongation regulator 1 -0.0141247
SYCP2L synaptonemal complex protein 2-like -0.0141117
CCDC7 coiled-coil domain containing 7 -0.0140983
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.0140949
SETDB2 SET domain, bifurcated 2 -0.0140808
EPN1 epsin 1 -0.0140745
PTK2B protein tyrosine kinase 2 beta -0.0140508
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.0140397
SNW1 SNW domain containing 1 -0.014029
BTNL9 butyrophilin-like 9 -0.0139598
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0138717
RBBP5 retinoblastoma binding protein 5 -0.0138521
BRD9 bromodomain containing 9 -0.0138234
LCLAT1 lysocardiolipin acyltransferase 1 -0.0137723
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0137658
OTUD7B OTU deubiquitinase 7B -0.0137625
KIAA0232 KIAA0232 -0.0137497
MAP4 microtubule-associated protein 4 -0.0137458
MRE11 MRE11 homolog, double strand break repair nuclease -0.0137453
SAP130 Sin3A-associated protein, 130kDa -0.0137357
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0137347
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0136956
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0136654
LASP1 LIM and SH3 protein 1 -0.0136564
SMAP2 small ArfGAP2 -0.013628
SCAF8 SR-related CTD-associated factor 8 -0.0135765
CBX5 chromobox homolog 5 -0.0135524
ARHGAP4 Rho GTPase activating protein 4 -0.0135375
NFE2 nuclear factor, erythroid 2 -0.0135144
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -0.0134484
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0134414
ARHGAP26 Rho GTPase activating protein 26 -0.0134259
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0134203
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0134059
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.0134046
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0133797
TLN1 talin 1 -0.013364
CBX1 chromobox homolog 1 -0.0133566
PFKL phosphofructokinase, liver -0.0133194
MTMR3 myotubularin related protein 3 -0.013309
TEX2 testis expressed 2 -0.0132962
NUP160 nucleoporin 160kDa -0.0132957
RPL28 ribosomal protein L28 -0.013267
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.0132517
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0132467
CENPL centromere protein L -0.0132437
MRPL30 mitochondrial ribosomal protein L30 -0.0132423
PHGDH phosphoglycerate dehydrogenase -0.0132249
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0132185
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0131943