K562_Valproic acid sodium salt_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 1µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_Valproic acid sodium salt_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SRPK2 SRSF protein kinase 2 0.0988964
DIAPH3 diaphanous-related formin 3 0.0749203
ARHGAP6 Rho GTPase activating protein 6 0.0744234
EPB41 erythrocyte membrane protein band 4.1 0.0721548
SMYD3 SET and MYND domain containing 3 0.0704093
GSE1 Gse1 coiled-coil protein 0.0691961
NIPBL Nipped-B homolog (Drosophila) 0.0672968
FOXP1 forkhead box P1 0.065326
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0623054
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0594417
PARD3 par-3 family cell polarity regulator 0.0574689
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0573826
ANKRD17 ankyrin repeat domain 17 0.0556162
AMBRA1 autophagy/beclin-1 regulator 1 0.0553379
SET SET nuclear proto-oncogene 0.0541961
SCAF11 SR-related CTD-associated factor 11 0.0538879
BMAL2 basic helix-loop-helix ARNT like 2 0.053428
SEC31A SEC31 homolog A (S. cerevisiae) 0.0531736
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0502857
TTC28 tetratricopeptide repeat domain 28 0.0499479
SPATS2 spermatogenesis associated, serine-rich 2 0.0482928
TCF12 transcription factor 12 0.0477784
ZFAND6 zinc finger, AN1-type domain 6 0.0474238
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0453372
RCOR1 REST corepressor 1 0.0451876
YARS1 tyrosyl-tRNA synthetase 1 0.0449535
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0445448
NEK7 NIMA-related kinase 7 0.0432908
ADGRV1 adhesion G protein-coupled receptor V1 0.04151
TRAP1 TNF receptor-associated protein 1 0.0414892
PCM1 pericentriolar material 1 0.0412616
PTH2R parathyroid hormone 2 receptor 0.0412086
SMIM44 small integral membrane protein 44 0.0411942
CELF1 CUGBP, Elav-like family member 1 0.0407041
GRB2 growth factor receptor-bound protein 2 0.0406533
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0405766
ZNF609 zinc finger protein 609 0.0405023
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0402903
CHD1 chromodomain helicase DNA binding protein 1 0.0397299
PHACTR4 phosphatase and actin regulator 4 0.0395365
LMNA lamin A/C 0.0395013
KHSRP KH-type splicing regulatory protein 0.0385412
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0379443
CUL1 cullin 1 0.0378477
TJP1 tight junction protein 1 0.0375229
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0368198
ASXL2 additional sex combs like transcriptional regulator 2 0.0362128
KMT2C lysine (K)-specific methyltransferase 2C 0.0360907
USP3 ubiquitin specific peptidase 3 0.0354957
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.0349881
TXNIP thioredoxin interacting protein 0.0347844
DCAF7 DDB1 and CUL4 associated factor 7 0.0346642
RAB1A RAB1A, member RAS oncogene family 0.034605
CENPE centromere protein E, 312kDa 0.034343
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0342827
LMAN1 lectin, mannose-binding, 1 0.0339456
HIC2 hypermethylated in cancer 2 0.0336576
RBBP6 retinoblastoma binding protein 6 0.0335952
KIF2A kinesin heavy chain member 2A 0.0335918
SPC25 SPC25, NDC80 kinetochore complex component 0.0334242
KIAA1958 KIAA1958 0.0334024
HIRA histone cell cycle regulator 0.0333141
OSBPL8 oxysterol binding protein-like 8 0.0329227
ITSN1 intersectin 1 (SH3 domain protein) 0.0328352
NCOR1 nuclear receptor corepressor 1 0.0327618
RB1CC1 RB1-inducible coiled-coil 1 0.0327043
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.0326278
RAP1A RAP1A, member of RAS oncogene family 0.0326196
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0326129
MAP2K1 mitogen-activated protein kinase kinase 1 0.0326005
EPHB6 EPH receptor B6 0.0325729
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.0325099
STAT5B signal transducer and activator of transcription 5B 0.0323201
CMC2 C-x(9)-C motif containing 2 0.0322891
KSR1 kinase suppressor of ras 1 0.0322541
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.0322432
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0321497
PDE8A phosphodiesterase 8A 0.0319401
AHI1 Abelson helper integration site 1 0.031936
UBN2 ubinuclein 2 0.0319234
USP6NL USP6 N-terminal like 0.031724
NFIA nuclear factor I/A 0.0316921
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0316243
MSI2 musashi RNA-binding protein 2 0.0315616
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0314156
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0312466
H2AC6 H2A clustered histone 6 0.0311493
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0311284
SESN2 sestrin 2 0.0309704
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0308622
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.030833
RPL32 ribosomal protein L32 0.030708
GATAD2B GATA zinc finger domain containing 2B 0.0305324
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.0304493
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.0303729
HDAC2 histone deacetylase 2 0.0302538
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.029903
CEP350 centrosomal protein 350kDa 0.0298696
AIG1 androgen-induced 1 0.0298545
CNKSR3 CNKSR family member 3 0.0297132
SIK2 salt-inducible kinase 2 0.0296988
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0296909
TBCK TBC1 domain containing kinase 0.0296469
MTDH metadherin 0.0296313
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0295052
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0294331
SMC3 structural maintenance of chromosomes 3 0.0293561
GOLGA4 golgin A4 0.029328
SMC4 structural maintenance of chromosomes 4 0.0291517
ELAVL1 ELAV like RNA binding protein 1 0.0289265
RNF121 ring finger protein 121 0.0288436
CLSPN claspin 0.0287852
PDE7A phosphodiesterase 7A 0.0284038
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 0.0281474
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.0281442
PLAGL1 pleiomorphic adenoma gene-like 1 0.028131
SDCCAG8 serologically defined colon cancer antigen 8 0.0280008
NCAPG non-SMC condensin I complex, subunit G 0.0279897
LIN54 lin-54 DREAM MuvB core complex component 0.027987
PICALM phosphatidylinositol binding clathrin assembly protein 0.0279802
POU2F1 POU class 2 homeobox 1 0.0279694
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0277845
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0277654
BRD4 bromodomain containing 4 0.0277096
PAIP2 poly(A) binding protein interacting protein 2 0.0276388
PRKCA protein kinase C, alpha 0.0275594
MYO9B myosin IXB 0.0275512
SON SON DNA binding protein 0.027495
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0273644
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0273348
RPS3 ribosomal protein S3 0.0272928
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0271976
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0271844
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0271409
GLG1 golgi glycoprotein 1 0.0271151
RLF rearranged L-myc fusion 0.0270782
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0270771
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0270575
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0269803
DNAH14 dynein, axonemal, heavy chain 14 0.0268346
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0266224
STIL SCL/TAL1 interrupting locus 0.0266073
KRT19 keratin 19, type I 0.0265216
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0264657
SETD5 SET domain containing 5 0.0263967
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0263761
ZMYND8 zinc finger, MYND-type containing 8 0.0263345
SORT1 sortilin 1 0.0263273
RPS16 ribosomal protein S16 0.0263155
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.0260892
RBM39 RNA binding motif protein 39 0.0260744
TFRC transferrin receptor 0.0259765
SRSF10 serine/arginine-rich splicing factor 10 0.0258625
BTBD1 BTB (POZ) domain containing 1 0.025815
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.0257174
WASL Wiskott-Aldrich syndrome-like 0.0256885
SGO1 shugoshin 1 0.0256038
ARID4B AT rich interactive domain 4B (RBP1-like) 0.025533
SULF2 sulfatase 2 0.0254929
OXCT1 3-oxoacid CoA transferase 1 0.0254834
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0254625
BCLAF1 BCL2-associated transcription factor 1 0.025461
QRICH1 glutamine-rich 1 0.0254179
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0252943
KDM2A lysine (K)-specific demethylase 2A 0.0252765
FRS2 fibroblast growth factor receptor substrate 2 0.025249
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.0251132
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0250996
SRRM2 serine/arginine repetitive matrix 2 0.0250885
FUBP1 far upstream element (FUSE) binding protein 1 0.0250776
ACTG1 actin gamma 1 0.0250706
LRRC4B leucine rich repeat containing 4B 0.0249966
CTCF CCCTC-binding factor (zinc finger protein) 0.0249849
RNF24 ring finger protein 24 0.0249584
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0248985
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.0248337
DPY19L4 dpy-19-like 4 (C. elegans) 0.0247682
ACO2 aconitase 2, mitochondrial 0.0247649
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0247484
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0247089
RNF111 ring finger protein 111 0.0246242
MTCL1 microtubule crosslinking factor 1 0.024594
COG7 component of oligomeric golgi complex 7 0.0244827
RIC8B RIC8 guanine nucleotide exchange factor B 0.0244352
RHOA ras homolog family member A 0.0243757
BCL2L1 BCL2-like 1 0.0242833
CKAP5 cytoskeleton associated protein 5 0.024251
AFDN afadin, adherens junction formation factor 0.0241154
GDI2 GDP dissociation inhibitor 2 0.0240754
MACF1 microtubule-actin crosslinking factor 1 0.024074
SACK1A scaffolding CK1 anchoring protein A 0.0239644
NUDCD1 NudC domain containing 1 0.0239321
CHD4 chromodomain helicase DNA binding protein 4 0.0238717
SPIDR scaffolding protein involved in DNA repair 0.0238077
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0237683
STIM1 stromal interaction molecule 1 0.0237555
CSNK1A1 casein kinase 1, alpha 1 0.0236764
NUP160 nucleoporin 160kDa 0.0235967
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.0234639
UBE2N ubiquitin-conjugating enzyme E2N 0.0234582
STK38 serine/threonine kinase 38 0.0234298
TTBK2 tau tubulin kinase 2 0.0234284
CLASP2 cytoplasmic linker associated protein 2 0.0234268
PKN2 protein kinase N2 0.0234124
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.0234108
NMU neuromedin U 0.0233875
AVL9 AVL9 homolog (S. cerevisiase) 0.023341
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0233199
CEP95 centrosomal protein 95kDa 0.0232889
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.0231636
WT1 Wilms tumor 1 0.0230839
MOCOS molybdenum cofactor sulfurase 0.0230352
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0230272
DOCK2 dedicator of cytokinesis 2 0.022974
FLNC filamin C, gamma 0.0229421
DGKH diacylglycerol kinase, eta 0.0228863
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0228737
SCAI suppressor of cancer cell invasion 0.0228018
MIA3 melanoma inhibitory activity family, member 3 0.0227155
PCYOX1 prenylcysteine oxidase 1 0.0227106
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0226986
GYPC glycophorin C (Gerbich blood group) 0.0226015
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0225982
XPO1 exportin 1 0.022583
ZNF292 zinc finger protein 292 0.0225708
RAD23B RAD23 homolog B (S. cerevisiae) 0.0223316
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0223244
YAF2 YY1 associated factor 2 0.0223223
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.0223056
WDR12 WD repeat domain 12 0.0222738
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0222719
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.0222528
ZNHIT1 zinc finger, HIT-type containing 1 0.0222248
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.022203
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.022175
RAI14 retinoic acid induced 14 0.02188
TPR translocated promoter region, nuclear basket protein 0.0218489
MYH9 myosin, heavy chain 9, non-muscle 0.021813
NUP214 nucleoporin 214kDa 0.0217832
MTPN myotrophin 0.0217799
BPTF bromodomain PHD finger transcription factor 0.0217771
SETX senataxin 0.0216668
DMD dystrophin 0.0216494
ATP5F1E ATP synthase F1 subunit epsilon 0.0215162
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.0214859
TMED8 transmembrane emp24 protein transport domain containing 8 0.0214763
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0214152
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0214149
SETD2 SET domain containing 2 0.0212023
LCORL ligand dependent nuclear receptor corepressor-like 0.021148
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.021123
CUL5 cullin 5 0.0211084
TAPT1 transmembrane anterior posterior transformation 1 0.0210759
SMC1A structural maintenance of chromosomes 1A 0.0210416
NCAPG2 non-SMC condensin II complex, subunit G2 0.0209867
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0209835
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.0209425
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.0209078
GOLPH3L golgi phosphoprotein 3-like 0.0208291
ARHGAP4 Rho GTPase activating protein 4 0.0208157
CNOT6 CCR4-NOT transcription complex, subunit 6 0.0207868
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.020779
HM13 histocompatibility (minor) 13 0.0207187
CLCN3 chloride channel, voltage-sensitive 3 0.0207093
USP47 ubiquitin specific peptidase 47 0.0206903
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.0206069
TMEM59 transmembrane protein 59 0.0205866
STX8 syntaxin 8 0.020555
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0205443
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.0205411
TUBA1B tubulin, alpha 1b 0.0204764
DESI2 desumoylating isopeptidase 2 0.0203953
MAPK8 mitogen-activated protein kinase 8 0.0203914
RTN4 reticulon 4 0.0203833
DHDDS dehydrodolichyl diphosphate synthase 0.0203754
PHAF1 phagosome assembly factor 1 0.0203189
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0202882
DDIT4 DNA-damage-inducible transcript 4 0.0202125
TASP1 taspase, threonine aspartase, 1 0.0201978
NCOA6 nuclear receptor coactivator 6 0.0201723
FYCO1 FYVE and coiled-coil domain containing 1 0.0200496
NBEAL1 neurobeachin-like 1 0.0200401
CDCA2 cell division cycle associated 2 0.0200217
PUM3 pumilio RNA binding family member 3 0.0200086
SLC38A6 solute carrier family 38, member 6 0.0199699
CDK4 cyclin-dependent kinase 4 0.0199695
KANSL3 KAT8 regulatory NSL complex subunit 3 0.0199652
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0199077
LTAP1 lipid transport auxiliary protein 1 0.019905
ATAD5 ATPase family, AAA domain containing 5 0.019904
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.0198675
USP53 ubiquitin specific peptidase 53 0.0197766
RTN3 reticulon 3 0.019747
TUT7 terminal uridylyl transferase 7 0.0196601
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.0196153
RSBN1L round spermatid basic protein 1-like 0.0196114
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0196093
VIM vimentin 0.0195822
DCP2 decapping mRNA 2 0.0195514
CDC27 cell division cycle 27 0.0195126
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0194749
PPP5C protein phosphatase 5, catalytic subunit 0.0194692
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0194619
PHIP pleckstrin homology domain interacting protein 0.0194415
WNK1 WNK lysine deficient protein kinase 1 0.019427
TESK2 testis-specific kinase 2 0.0194214
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.0193956
TSC22D2 TSC22 domain family, member 2 0.0193793
STK17B serine/threonine kinase 17b 0.019337
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.019328
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.0193169
GSPT1 G1 to S phase transition 1 0.0193105
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.0192879
TP63 tumor protein p63 0.0192833
HCFC1 host cell factor C1 0.0191949
EML4 echinoderm microtubule associated protein like 4 0.0191845
SAMD1 sterile alpha motif domain containing 1 0.019164
USP15 ubiquitin specific peptidase 15 0.0191581
CAPNS1 calpain, small subunit 1 0.0191427
APLP2 amyloid beta (A4) precursor-like protein 2 0.0191173
DENND5B DENN/MADD domain containing 5B 0.0191133
ANXA11 annexin A11 0.0191114
RTCA RNA 3'-terminal phosphate cyclase 0.0189956
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.0189954
ATM ATM serine/threonine kinase 0.0189862
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0189412
NOL10 nucleolar protein 10 0.0189097
ADD3 adducin 3 (gamma) 0.018865
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.0188533
NDC80 NDC80 kinetochore complex component 0.018806
CEP76 centrosomal protein 76kDa 0.0187511
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.0186948
ANKRD23 ankyrin repeat domain 23 0.0186446
AXIN1 axin 1 0.0186404
NUP54 nucleoporin 54kDa 0.0186328
PRKN parkin RBR E3 ubiquitin protein ligase 0.0186171
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 0.0185812
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0185361
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0185292
C3ORF38 chromosome 3 open reading frame 38 0.0185213
H4C3 H4 clustered histone 3 0.0184486
GPANK1 G patch domain and ankyrin repeats 1 0.0184425
CDK8 cyclin-dependent kinase 8 0.0184397
RNF38 ring finger protein 38 0.0184315
TMCC1 transmembrane and coiled-coil domain family 1 0.0184195
PDCL2 phosducin-like 2 0.0184096
SAMD4A sterile alpha motif domain containing 4A 0.0184047
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.0183617
SRSF4 serine/arginine-rich splicing factor 4 0.0183559
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.0183417
TRIM33 tripartite motif containing 33 0.0183097
ATF6 activating transcription factor 6 0.0182909
FAM222B family with sequence similarity 222, member B 0.0182845
DPY19L3 dpy-19-like 3 (C. elegans) 0.0182741
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0182281
ZYG11B zyg-11 family member B, cell cycle regulator 0.0181884
FAM171A1 family with sequence similarity 171, member A1 0.0181601
GOSR1 golgi SNAP receptor complex member 1 0.0181519
DLC1 DLC1 Rho GTPase activating protein 0.0180929
HSPB1 heat shock 27kDa protein 1 0.018083
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 0.0180599
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0180559
CEP85L centrosomal protein 85kDa-like 0.0180001
AK4 adenylate kinase 4 0.0179956
HIPK1 homeodomain interacting protein kinase 1 0.0179337
KAT6A K(lysine) acetyltransferase 6A 0.0179178
UBAP2 ubiquitin associated protein 2 0.0178797
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0178311
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0177951
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0177927
GABPB1 GA binding protein transcription factor, beta subunit 1 0.0177616
ANAPC10 anaphase promoting complex subunit 10 0.0177434
CAPRIN1 cell cycle associated protein 1 0.0177355
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.0176954
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.0176786
RHEB Ras homolog enriched in brain 0.017673
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.01767
SSH1 slingshot protein phosphatase 1 0.0176616
USP8 ubiquitin specific peptidase 8 0.0176318
EXOC6B exocyst complex component 6B 0.017618
MRPL37 mitochondrial ribosomal protein L37 0.017611
ERBIN erbb2 interacting protein 0.0176013
CDC16 cell division cycle 16 0.0175685
TET2 tet methylcytosine dioxygenase 2 0.0175492
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.017542
SERINC5 serine incorporator 5 0.0174275
PSPC1 paraspeckle component 1 0.0174168
ODR4 odr-4 GPCR localization factor homolog 0.017383
RAD23A RAD23 homolog A (S. cerevisiae) 0.0173712
MEGF9 multiple EGF-like-domains 9 0.0173656
ZFR zinc finger RNA binding protein 0.0173572
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0173025
KMT2E lysine (K)-specific methyltransferase 2E 0.0172751
CLTC clathrin, heavy chain (Hc) 0.01726
USP24 ubiquitin specific peptidase 24 0.0172598
BID BH3 interacting domain death agonist 0.0172437
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0172217
RBM15 RNA binding motif protein 15 0.0172181
TRIM27 tripartite motif containing 27 0.0171991
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0171952
PTPRJ protein tyrosine phosphatase, receptor type, J 0.017186
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.01714
IARS1 isoleucyl-tRNA synthetase 1 0.0171061
PDE4D phosphodiesterase 4D, cAMP-specific 0.0170983
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.0170759
CNOT8 CCR4-NOT transcription complex, subunit 8 0.0170572
TLK1 tousled-like kinase 1 0.0170568
ABI1 abl-interactor 1 0.017036
UCK2 uridine-cytidine kinase 2 0.0170255
USO1 USO1 vesicle transport factor 0.0169962
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0169712
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.0169143
DENR density-regulated protein 0.0169139
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.016883
DAGLB diacylglycerol lipase, beta 0.0168752
YIPF2 Yip1 domain family, member 2 0.0168406
GIGYF1 GRB10 interacting GYF protein 1 0.0168359
ARL8B ADP-ribosylation factor-like 8B 0.0168315
PRR12 proline rich 12 0.016807
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.0168023
TBCE tubulin folding cofactor E 0.0167719
STK24 serine/threonine kinase 24 0.0167669
TP53BP1 tumor protein p53 binding protein 1 0.0167479
NPEPPS aminopeptidase puromycin sensitive 0.0167389
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.016725
ING5 inhibitor of growth family, member 5 0.0167192
TRPS1 trichorhinophalangeal syndrome I 0.0166736
KCTD13 potassium channel tetramerization domain containing 13 0.0166442
SRSF11 serine/arginine-rich splicing factor 11 0.0166377
ZDHHC3 zinc finger, DHHC-type containing 3 0.0166087
STX2 syntaxin 2 0.016604
GNS glucosamine (N-acetyl)-6-sulfatase 0.0165951
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.0165929
BCL7A B-cell CLL/lymphoma 7A 0.0165821
FBXO34 F-box protein 34 0.0165556
AHDC1 AT hook, DNA binding motif, containing 1 0.0165506
TMPO thymopoietin 0.0165479
CALN1 calneuron 1 0.0165315
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0165196
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.016437
DEGS1 delta(4)-desaturase, sphingolipid 1 0.016425
XPO7 exportin 7 0.0164131
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.0163434
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.0163257
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0162926
FLT1 fms-related tyrosine kinase 1 0.0162379
DHRS7B dehydrogenase/reductase (SDR family) member 7B 0.0162181
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.0161994
BRD1 bromodomain containing 1 0.0161897
FUBP3 far upstream element (FUSE) binding protein 3 0.0161831
TCF20 transcription factor 20 (AR1) 0.0161502
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.0161499
FNIP2 folliculin interacting protein 2 0.0161046
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 0.0161041
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.0161022
PRKCI protein kinase C, iota 0.0160751
GATA2 GATA binding protein 2 0.0160232
NDC1 NDC1 transmembrane nucleoporin 0.0160145
CDC73 cell division cycle 73 0.0160011
ZNF678 zinc finger protein 678 0.0159977
ZNF655 zinc finger protein 655 0.0159806
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.0159393
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.0159312
CLASP1 cytoplasmic linker associated protein 1 0.0159277
MICOS10 mitochondrial contact site and cristae organizing system subunit 10 0.015907
AHCYL1 adenosylhomocysteinase-like 1 0.0158999
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.0158767
BTG1 B-cell translocation gene 1, anti-proliferative 0.0158363
BTG2 BTG family, member 2 0.015788
DNAH8 dynein, axonemal, heavy chain 8 0.0157819
CCM2 cerebral cavernous malformation 2 0.0157791
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.0157755
RYBP RING1 and YY1 binding protein 0.0157629
ARMC8 armadillo repeat containing 8 0.0157205
TRIM13 tripartite motif containing 13 0.0157183
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0157108
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0156827
CCND3 cyclin D3 0.0156799
AGFG1 ArfGAP with FG repeats 1 0.015672
TCF25 transcription factor 25 (basic helix-loop-helix) 0.015672
RPAP2 RNA polymerase II associated protein 2 0.015665
KMT2D lysine (K)-specific methyltransferase 2D 0.0156637
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0156163
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 0.0156064
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0156031
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 0.0156007
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 0.0155992
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0155963
RNF185 ring finger protein 185 0.0155884
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.0155801
CENPN centromere protein N 0.0155396
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.0155363
KTN1 kinectin 1 (kinesin receptor) 0.0155362
C18ORF25 chromosome 18 open reading frame 25 0.015528
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.0154763
TPX2 TPX2, microtubule-associated 0.015471
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.0154507
SAPCD2 suppressor APC domain containing 2 0.0154428
AFG3L2 AFG3-like AAA ATPase 2 0.0154262
UIMC1 ubiquitin interaction motif containing 1 0.0153802

decreased expression

Symbol Name Standardized Value
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.0891225
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.087119
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0862696
ZFPM2 zinc finger protein, FOG family member 2 -0.0861857
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0776784
FGF13 fibroblast growth factor 13 -0.0697544
FHIT fragile histidine triad -0.0692743
HBG2 hemoglobin, gamma G -0.0676625
DARS1 aspartyl-tRNA synthetase 1 -0.0557566
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0541518
ATG7 autophagy related 7 -0.0532607
FDPS farnesyl diphosphate synthase -0.0512098
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0508682
MCAM melanoma cell adhesion molecule -0.0498501
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0488343
CENPF centromere protein F, 350/400kDa -0.0481242
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0459546
GDA guanine deaminase -0.0453613
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0448834
DNM2 dynamin 2 -0.0448731
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0448147
NIBAN1 niban apoptosis regulator 1 -0.0446351
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0445611
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0438188
HBG1 hemoglobin, gamma A -0.0434558
TMEM135 transmembrane protein 135 -0.0431848
MYO1D myosin ID -0.043072
CMIP c-Maf inducing protein -0.0425334
HBE1 hemoglobin, epsilon 1 -0.0421859
ZEB2 zinc finger E-box binding homeobox 2 -0.0417975
MUSK muscle, skeletal, receptor tyrosine kinase -0.0411801
UBE3C ubiquitin protein ligase E3C -0.0411257
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0408678
DOCK8 dedicator of cytokinesis 8 -0.0401987
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.040134
LTBP1 latent transforming growth factor beta binding protein 1 -0.0400038
TAC4 tachykinin 4 (hemokinin) -0.0398278
DIAPH1 diaphanous-related formin 1 -0.0396543
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0391366
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0390094
SLC39A11 solute carrier family 39, member 11 -0.0382254
RPL28 ribosomal protein L28 -0.0382021
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0377483
EXOC4 exocyst complex component 4 -0.0376761
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0373979
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0368354
TBCA tubulin folding cofactor A -0.0367435
NCAM2 neural cell adhesion molecule 2 -0.035712
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0355946
SCARB1 scavenger receptor class B, member 1 -0.0350736
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0339973
RSRC1 arginine/serine-rich coiled-coil 1 -0.0339334
CCNY cyclin Y -0.0338913
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0337445
SSBP3 single stranded DNA binding protein 3 -0.0334901
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.033055
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.0329109
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0326216
THADA thyroid adenoma associated -0.0326058
ZBTB11 zinc finger and BTB domain containing 11 -0.0325787
PRKCB protein kinase C, beta -0.0325361
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0324515
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0320847
BCOR BCL6 corepressor -0.0317291
ARL15 ADP-ribosylation factor-like 15 -0.0314989
WARS1 tryptophanyl-tRNA synthetase 1 -0.0313403
ANTXR2 anthrax toxin receptor 2 -0.0312397
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.03108
CYRIB CYFIP related Rac1 interactor B -0.0306563
MCU mitochondrial calcium uniporter -0.0304749
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0304539
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.0302866
UBL4A ubiquitin-like 4A -0.0300864
MCM7 minichromosome maintenance complex component 7 -0.0297669
RABGAP1L RAB GTPase activating protein 1-like -0.0296398
GOLGA2 golgin A2 -0.0296303
THOC2 THO complex 2 -0.0295876
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0295655
NUP210 nucleoporin 210kDa -0.0293795
NBAS neuroblastoma amplified sequence -0.0293726
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0292719
PHKB phosphorylase kinase, beta -0.0292329
HDAC8 histone deacetylase 8 -0.0289723
FAM193A family with sequence similarity 193, member A -0.0289045
TFCP2 transcription factor CP2 -0.0288396
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0286865
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0286457
TGOLN2 trans-golgi network protein 2 -0.0285732
HDLBP high density lipoprotein binding protein -0.0285367
STAG2 stromal antigen 2 -0.0284277
TTC3 tetratricopeptide repeat domain 3 -0.0282811
RPL15 ribosomal protein L15 -0.0282471
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0281673
HMBOX1 homeobox containing 1 -0.027883
EXOC6 exocyst complex component 6 -0.0276878
PLD3 phospholipase D family, member 3 -0.0275378
KCTD20 potassium channel tetramerization domain containing 20 -0.0271659
MVD mevalonate (diphospho) decarboxylase -0.027056
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -0.0270476
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0269803
ZNF207 zinc finger protein 207 -0.0269096
PARK7 parkinson protein 7 -0.0269003
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.0268907
SOS1 son of sevenless homolog 1 (Drosophila) -0.0268215
RPS8 ribosomal protein S8 -0.0268089
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0266589
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0266533
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0266343
FBXO17 F-box protein 17 -0.0264206
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0263858
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -0.0262708
RUNX1 runt-related transcription factor 1 -0.0262048
ATXN2 ataxin 2 -0.0261653
SGMS1 sphingomyelin synthase 1 -0.0260456
PTPRA protein tyrosine phosphatase, receptor type, A -0.0260276
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0260265
GPC5 glypican 5 -0.0259434
NSRP1 nuclear speckle splicing regulatory protein 1 -0.0258554
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.0257871
TTC7B tetratricopeptide repeat domain 7B -0.0256409
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0256342
POGZ pogo transposable element with ZNF domain -0.0255138
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -0.0254708
FBXO42 F-box protein 42 -0.0254406
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0254388
SFXN5 sideroflexin 5 -0.0251918
PHF20 PHD finger protein 20 -0.025169
MFGE8 milk fat globule-EGF factor 8 protein -0.0249233
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0249046
STRIP2 striatin interacting protein 2 -0.0247833
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0247678
MICU1 mitochondrial calcium uptake 1 -0.0246862
ETNK1 ethanolamine kinase 1 -0.0246677
RANBP1 RAN binding protein 1 -0.0245953
BTBD7 BTB (POZ) domain containing 7 -0.0243985
MAP4 microtubule-associated protein 4 -0.0242509
PHTF2 putative homeodomain transcription factor 2 -0.0242439
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0242098
RORA RAR-related orphan receptor A -0.0241899
AMOTL1 angiomotin like 1 -0.0241201
GLO1 glyoxalase I -0.0241121
NUMB numb homolog (Drosophila) -0.0239923
NRIP1 nuclear receptor interacting protein 1 -0.0239898
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0238941
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0238174
MRPL13 mitochondrial ribosomal protein L13 -0.0237873
RELN reelin -0.0237782
ARID3A AT rich interactive domain 3A (BRIGHT-like) -0.0237655
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.0237557
RPL30 ribosomal protein L30 -0.0236777
TNPO2 transportin 2 -0.0236363
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0236206
MLXIP MLX interacting protein -0.0235656
TPI1 triosephosphate isomerase 1 -0.0235299
EMC3 ER membrane protein complex subunit 3 -0.0234289
ATG10 autophagy related 10 -0.0233741
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0233382
OSBPL3 oxysterol binding protein-like 3 -0.0232213
TRAK1 trafficking protein, kinesin binding 1 -0.0232191
CPED1 cadherin-like and PC-esterase domain containing 1 -0.023209
RNF216 ring finger protein 216 -0.0232009
SPPL3 signal peptide peptidase like 3 -0.0231766
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0231434
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0231198
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0230865
NRDC nardilysin convertase -0.0230417
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0230378
MGA MGA, MAX dimerization protein -0.0229631
SASH1 SAM and SH3 domain containing 1 -0.0228895
PCNX4 pecanex 4 -0.0228771
NKTR natural killer cell triggering receptor -0.0228483
PGRMC2 progesterone receptor membrane component 2 -0.0227358
MTF2 metal response element binding transcription factor 2 -0.0226584
FBXL20 F-box and leucine-rich repeat protein 20 -0.0226377
XPR1 xenotropic and polytropic retrovirus receptor 1 -0.0226008
RPN1 ribophorin I -0.0226006
WSB1 WD repeat and SOCS box containing 1 -0.0225985
CBR4 carbonyl reductase 4 -0.0225332
CCAR1 cell division cycle and apoptosis regulator 1 -0.022513
PROS1 protein S (alpha) -0.0223555
RPS27 ribosomal protein S27 -0.0223251
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0222236
ENKUR enkurin, TRPC channel interacting protein -0.0221942
KIF13A kinesin family member 13A -0.0221934
POTEF POTE ankyrin domain family, member F -0.0221822
KLHL22 kelch-like family member 22 -0.0220675
ZNF562 zinc finger protein 562 -0.0220662
GLUL glutamate-ammonia ligase -0.0220028
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0219706
DENND4A DENN/MADD domain containing 4A -0.0219178
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.0218702
SSR4 signal sequence receptor, delta -0.0218674
HEATR1 HEAT repeat containing 1 -0.0218622
RPL18 ribosomal protein L18 -0.0217898
MIB1 mindbomb E3 ubiquitin protein ligase 1 -0.0217186
KIDINS220 kinase D-interacting substrate, 220kDa -0.0216628
ORC5 origin recognition complex, subunit 5 -0.0216455
RPL37 ribosomal protein L37 -0.0216332
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0216023
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -0.0215979
LDAH lipid droplet associated hydrolase -0.0215826
VCL vinculin -0.0215594
PRC1 protein regulator of cytokinesis 1 -0.0215274
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.0215106
MRTFB myocardin related transcription factor B -0.021429
TNIK TRAF2 and NCK interacting kinase -0.0213532
ZBTB38 zinc finger and BTB domain containing 38 -0.0213325
TGFBR3 transforming growth factor, beta receptor III -0.0213264
AKAP11 A kinase (PRKA) anchor protein 11 -0.0213087
ZNF124 zinc finger protein 124 -0.0212812
KPNB1 karyopherin (importin) beta 1 -0.0211772
HEPH hephaestin -0.0211289
NUP107 nucleoporin 107kDa -0.0210074
TMEM248 transmembrane protein 248 -0.0209657
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -0.0208671
ATP5MC3 ATP synthase membrane subunit c locus 3 -0.0207942
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.02079
ACOD1 aconitate decarboxylase 1 -0.0207756
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0207557
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.020724
USP48 ubiquitin specific peptidase 48 -0.0206842
CDC45 cell division cycle 45 -0.0206242
HIP1 huntingtin interacting protein 1 -0.0205108
ARMH3 armadillo like helical domain containing 3 -0.0204935
RCC1 regulator of chromosome condensation 1 -0.0204841
GSK3B glycogen synthase kinase 3 beta -0.0204443
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0204369
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.0204332
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0203927
KAZN kazrin, periplakin interacting protein -0.0203898
RBBP4 retinoblastoma binding protein 4 -0.0203226
SRGN serglycin -0.0203028
QSER1 glutamine and serine rich 1 -0.0202798
RPL35 ribosomal protein L35 -0.020236
MFN2 mitofusin 2 -0.0202314
H2AZ2 H2A.Z variant histone 2 -0.0201924
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0201692
ELOVL5 ELOVL fatty acid elongase 5 -0.0201616
MYO18B myosin XVIIIB -0.0201183
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0200891
SOX6 SRY (sex determining region Y)-box 6 -0.0200407
UBE3D ubiquitin protein ligase E3D -0.0200377
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0200351
BRCA1 breast cancer 1, early onset -0.0200031
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.019976
CDK17 cyclin-dependent kinase 17 -0.0199388
UBE2Z ubiquitin-conjugating enzyme E2Z -0.0198263
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0198218
GON4L gon-4-like (C. elegans) -0.0197717
TRAPPC12 trafficking protein particle complex 12 -0.0197399
MEIS2 Meis homeobox 2 -0.0195163
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.019504
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.019473
HBZ hemoglobin, zeta -0.0194585
CCDC137 coiled-coil domain containing 137 -0.0194583
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0194139
RHD Rh blood group, D antigen -0.0193548
RAI1 retinoic acid induced 1 -0.0193337
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0192503
MIPOL1 mirror-image polydactyly 1 -0.0192495
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.019217
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0191848
ENO1 enolase 1, (alpha) -0.0191724
MYH10 myosin, heavy chain 10, non-muscle -0.0191509
MBD4 methyl-CpG binding domain protein 4 -0.0190523
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.019027
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -0.0190187
CHD9 chromodomain helicase DNA binding protein 9 -0.0189873
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0189302
UBE2O ubiquitin-conjugating enzyme E2O -0.0189255
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.0188726
TAOK1 TAO kinase 1 -0.0188518
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.018821
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0187836
YTHDC2 YTH domain containing 2 -0.0187409
TUBB4B tubulin, beta 4B class IVb -0.0187189
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -0.0186907
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0186866
ACAD10 acyl-CoA dehydrogenase family, member 10 -0.018596
PTK2 protein tyrosine kinase 2 -0.0185843
PHF3 PHD finger protein 3 -0.0185414
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.018501
MDN1 MDN1, midasin homolog (yeast) -0.0184898
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0184759
MRPS25 mitochondrial ribosomal protein S25 -0.018457
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0184549
ABHD2 abhydrolase domain containing 2 -0.018452
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.0184367
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0183116
ZC3H4 zinc finger CCCH-type containing 4 -0.0182949
DGCR8 DGCR8 microprocessor complex subunit -0.0182909
JAK1 Janus kinase 1 -0.0182309
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0181535
DSTYK dual serine/threonine and tyrosine protein kinase -0.018146
MED13 mediator complex subunit 13 -0.0181422
C16ORF95 chromosome 16 open reading frame 95 -0.0181301
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0181082
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -0.0181001
E2F3 E2F transcription factor 3 -0.0180319
ZNF710 zinc finger protein 710 -0.0180311
SOGA1 suppressor of glucose, autophagy associated 1 -0.018026
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0180238
CCDC93 coiled-coil domain containing 93 -0.0180098
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.0180014
SH3GL1 SH3-domain GRB2-like 1 -0.0179628
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.0178589
PHF19 PHD finger protein 19 -0.0178379
TFR2 transferrin receptor 2 -0.017834
VPS50 VPS50 subunit of EARP/GARPII complex -0.0178245
CDC25C cell division cycle 25C -0.0178147
KIFC3 kinesin family member C3 -0.0177917
XRN2 5'-3' exoribonuclease 2 -0.017776
ANK1 ankyrin 1, erythrocytic -0.0177461
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.017723
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0176786
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -0.0176738
TOM1L2 target of myb1-like 2 (chicken) -0.0176573
NOP56 NOP56 ribonucleoprotein -0.0176496
ZCCHC10 zinc finger, CCHC domain containing 10 -0.0176495
BLVRB biliverdin reductase B -0.0176409
NSUN6 NOP2/Sun domain family, member 6 -0.017635
FANCD2 Fanconi anemia, complementation group D2 -0.0175872
TASOR2 transcription activation suppressor family member 2 -0.0175819
ACACA acetyl-CoA carboxylase alpha -0.017518
AEBP2 AE binding protein 2 -0.0175051
TFF1 trefoil factor 1 -0.0175005
HMGA1 high mobility group AT-hook 1 -0.0174888
SPAG9 sperm associated antigen 9 -0.0174822
CERS6 ceramide synthase 6 -0.0174756
CCDC88A coiled-coil domain containing 88A -0.0174532
GCN1 GCN1 activator of EIF2AK4 -0.0174323
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.017411
NF2 neurofibromin 2 (merlin) -0.0174063
TOR1AIP2 torsin A interacting protein 2 -0.0174019
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -0.0173941
CFAP36 cilia and flagella associated protein 36 -0.0172726
TBL1X transducin (beta)-like 1X-linked -0.0172708
ACIN1 apoptotic chromatin condensation inducer 1 -0.0172349
ZNF782 zinc finger protein 782 -0.0172241
TLN1 talin 1 -0.017207
ARHGAP18 Rho GTPase activating protein 18 -0.0171913
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0171807
F8 coagulation factor VIII, procoagulant component -0.0171772
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.017171
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -0.0171461
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0171307
METTL16 methyltransferase like 16 -0.0171064
PFKL phosphofructokinase, liver -0.0170059
RNF10 ring finger protein 10 -0.016955
EIF5B eukaryotic translation initiation factor 5B -0.0169419
CEP83 centrosomal protein 83kDa -0.0169075
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -0.0168693
RDX radixin -0.0168553
MYO18A myosin XVIIIA -0.016847
WDR44 WD repeat domain 44 -0.0168463
ZNF445 zinc finger protein 445 -0.0168445
C6ORF89 chromosome 6 open reading frame 89 -0.0168349
RPL7A ribosomal protein L7a -0.0167671
UBAC2 UBA domain containing 2 -0.0167573
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0167433
RPL31 ribosomal protein L31 -0.016732
ZNF789 zinc finger protein 789 -0.0167239
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -0.0167201
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0167079
PTRH2 peptidyl-tRNA hydrolase 2 -0.0166705
AOPEP aminopeptidase O (putative) -0.0166432
NEK9 NIMA-related kinase 9 -0.0165803
TRRAP transformation/transcription domain-associated protein -0.0165784
THEM4 thioesterase superfamily member 4 -0.0165773
FCHSD2 FCH and double SH3 domains 2 -0.0165574
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.0164983
ZNF326 zinc finger protein 326 -0.0164967
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0164832
VIRMA vir like m6A methyltransferase associated -0.0164655
CHPT1 choline phosphotransferase 1 -0.0164302
ACTN1 actinin, alpha 1 -0.0164272
ZBTB7A zinc finger and BTB domain containing 7A -0.016423
SELENOI selenoprotein I -0.016412
SQSTM1 sequestosome 1 -0.0163915
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0163842
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0163758
FUCA2 fucosidase, alpha-L- 2, plasma -0.0163499
METTL2A methyltransferase like 2A -0.016336
FOSL1 FOS-like antigen 1 -0.0163344
ARHGAP24 Rho GTPase activating protein 24 -0.0162414
MSN moesin -0.0162344
COXFA4 cytochrome c oxidase associated subunit FA4 -0.0161944
TTC27 tetratricopeptide repeat domain 27 -0.0161931
STAT2 signal transducer and activator of transcription 2, 113kDa -0.0161568
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0161523
ANKFY1 ankyrin repeat and FYVE domain containing 1 -0.0161042
MYO19 myosin XIX -0.0160797
IMMT inner membrane protein, mitochondrial -0.0160693
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.0160442
ZCCHC8 zinc finger, CCHC domain containing 8 -0.0160182
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.016001
TPST2 tyrosylprotein sulfotransferase 2 -0.0159966
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.015949
LIMD1 LIM domains containing 1 -0.0159466
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -0.0159258
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.0158897
ADAL adenosine deaminase-like -0.0158815
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.015877
AZIN1 antizyme inhibitor 1 -0.015877
ASL argininosuccinate lyase -0.0158656
CPAP centrosome assembly and centriole elongation protein -0.0158632
TFB1M transcription factor B1, mitochondrial -0.0158083
SNU13 small nuclear ribonucleoprotein 13 -0.0157998
TCAIM T cell activation inhibitor, mitochondrial -0.0157704
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.0157514
ZNF804A zinc finger protein 804A -0.0156958
RBM14-RBM4 RBM14-RBM4 readthrough -0.0156913
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0156659
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.0156567
EMSY EMSY transcriptional repressor, BRCA2 interacting -0.0156515
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0156511
ZFPM1 zinc finger protein, FOG family member 1 -0.0156479
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.0156276
NCOA4 nuclear receptor coactivator 4 -0.0156162
ABHD18 abhydrolase domain containing 18 -0.015607
CEP152 centrosomal protein 152kDa -0.0155964
GIGYF2 GRB10 interacting GYF protein 2 -0.0155901
DST dystonin -0.0155337
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -0.0155323
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -0.015531
PBK PDZ binding kinase -0.0155003
PIGU phosphatidylinositol glycan anchor biosynthesis, class U -0.0154992
TBC1D5 TBC1 domain family, member 5 -0.0153654
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -0.0153364
RPL27A ribosomal protein L27a -0.0153208
VDAC2 voltage-dependent anion channel 2 -0.0153035
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0152937
TEX10 testis expressed 10 -0.0152625
GAN gigaxonin -0.015233
PUS7 pseudouridylate synthase 7 (putative) -0.0152252
MSL2 male-specific lethal 2 homolog (Drosophila) -0.0151982
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -0.0151879
INO80 INO80 complex subunit -0.0151711
CTSB cathepsin B -0.0151549
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.0151315
RNF2 ring finger protein 2 -0.0151116
SQLE squalene epoxidase -0.0150971
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) -0.0150777
SIL1 SIL1 nucleotide exchange factor -0.0150333
IDE insulin-degrading enzyme -0.0150214
HMGXB3 HMG box domain containing 3 -0.0150167
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -0.0149824
ACSF3 acyl-CoA synthetase family member 3 -0.0149475
CR1L complement component (3b/4b) receptor 1-like -0.0149471
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0148958
ZGRF1 zinc finger, GRF-type containing 1 -0.0148482
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -0.0148221
SSX3 synovial sarcoma, X breakpoint 3 -0.014817
RRM2 ribonucleotide reductase M2 -0.0148097
HLTF helicase-like transcription factor -0.0147992
CFAP70 cilia and flagella associated protein 70 -0.0147931
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.0147625
TOX4 TOX high mobility group box family member 4 -0.0147567
SNX3 sorting nexin 3 -0.014748
DSCC1 DNA replication and sister chromatid cohesion 1 -0.014742
NT5C2 5'-nucleotidase, cytosolic II -0.0147385
CAMKMT calmodulin-lysine N-methyltransferase -0.0147319
NIPSNAP2 nipsnap homolog 2 -0.0147235
NLN neurolysin (metallopeptidase M3 family) -0.0147219
CDK13 cyclin-dependent kinase 13 -0.01472
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.0147076
MTA3 metastasis associated 1 family, member 3 -0.0147003
HPS5 Hermansky-Pudlak syndrome 5 -0.0146885
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0146828
CCNI cyclin I -0.0146648
MED25 mediator complex subunit 25 -0.0146595
RPL7L1 ribosomal protein L7-like 1 -0.0146505
MYDGF myeloid-derived growth factor -0.0146154
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.0146057
USP45 ubiquitin specific peptidase 45 -0.0145915
PTPRS protein tyrosine phosphatase, receptor type, S -0.0145697
WDR59 WD repeat domain 59 -0.014558
CCDC88C coiled-coil domain containing 88C -0.014541
TMEM167A transmembrane protein 167A -0.0145328
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0145263
XBP1 X-box binding protein 1 -0.0145
SLC38A10 solute carrier family 38, member 10 -0.0144798
CARS1 cysteinyl-tRNA synthetase 1 -0.014455
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -0.0144491
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -0.0144245
CHMP4B charged multivesicular body protein 4B -0.0144231
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -0.014416
RPL6 ribosomal protein L6 -0.0144114
IST1 increased sodium tolerance 1 homolog (yeast) -0.0144039
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -0.0143965
MCPH1 microcephalin 1 -0.0143914
NUMBL numb homolog (Drosophila)-like -0.0143846
UBB ubiquitin B -0.0143836
KMT5B lysine methyltransferase 5B -0.0143189
BAIAP2L1 BAI1-associated protein 2-like 1 -0.014307
PRR14L proline rich 14-like -0.0142973
MORC3 MORC family CW-type zinc finger 3 -0.0142871
MRS2 MRS2 magnesium transporter -0.0142624
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0142615
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.0142235