K562_Valproic acid sodium salt_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 10µM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
Similar Terms
Downloads & Tools

Genes

1000 genes differentially expressed following the K562_Valproic acid sodium salt_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.108449
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0824251
BMAL2 basic helix-loop-helix ARNT like 2 0.0783334
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0778406
COP1 COP1 E3 ubiquitin ligase 0.0734279
XPO1 exportin 1 0.0717503
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0682892
VCL vinculin 0.0674421
FGF13 fibroblast growth factor 13 0.0673211
SMYD3 SET and MYND domain containing 3 0.0668272
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0567725
ENSA endosulfine alpha 0.0516179
ZNF638 zinc finger protein 638 0.0514167
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.051141
EVI5 ecotropic viral integration site 5 0.0509716
DCAF6 DDB1 and CUL4 associated factor 6 0.0495839
AHCYL2 adenosylhomocysteinase-like 2 0.0491427
CDK6 cyclin-dependent kinase 6 0.0485726
PLCL1 phospholipase C-like 1 0.0484801
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0481234
ZCCHC7 zinc finger, CCHC domain containing 7 0.0474898
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.04619
BABAM2 BRISC and BRCA1 A complex member 2 0.0454323
HBG2 hemoglobin, gamma G 0.0447996
RHAG Rh-associated glycoprotein 0.0444266
RPL32 ribosomal protein L32 0.0441787
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.0436889
RNF217 ring finger protein 217 0.043133
BCR breakpoint cluster region 0.0417668
TGFB1 transforming growth factor, beta 1 0.0414433
CUX1 cut-like homeobox 1 0.0407092
MIER1 mesoderm induction early response 1, transcriptional regulator 0.0402127
ARL15 ADP-ribosylation factor-like 15 0.0395815
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.039472
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.039147
CPED1 cadherin-like and PC-esterase domain containing 1 0.0388136
RNF24 ring finger protein 24 0.0387591
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0383308
DCP2 decapping mRNA 2 0.0383255
FCHSD2 FCH and double SH3 domains 2 0.0380793
SRPK2 SRSF protein kinase 2 0.0380498
ZNF207 zinc finger protein 207 0.0379614
CARD11 caspase recruitment domain family, member 11 0.0373693
RSRP1 arginine/serine-rich protein 1 0.0371636
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.0369183
FAM168A family with sequence similarity 168, member A 0.0365658
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0363941
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0362329
MMS22L MMS22-like, DNA repair protein 0.0359056
TFRC transferrin receptor 0.0355429
BCAP29 B-cell receptor-associated protein 29 0.0353319
PEAK1 pseudopodium-enriched atypical kinase 1 0.0353186
ADNP activity-dependent neuroprotector homeobox 0.0352855
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.0351536
AFG2A AFG2 AAA ATPase homolog A 0.0349433
SDCCAG8 serologically defined colon cancer antigen 8 0.0348841
GAB2 GRB2-associated binding protein 2 0.0348747
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0347612
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0347468
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.0346919
CRTC1 CREB regulated transcription coactivator 1 0.0345149
SLC38A2 solute carrier family 38, member 2 0.0345099
HIP1 huntingtin interacting protein 1 0.0342596
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 0.0342481
TNRC6A trinucleotide repeat containing 6A 0.0342439
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0340987
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0338305
LAMP2 lysosomal-associated membrane protein 2 0.0337774
GANAB glucosidase, alpha; neutral AB 0.0335962
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0335712
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0334193
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0332468
CAMKMT calmodulin-lysine N-methyltransferase 0.0331755
NCAM2 neural cell adhesion molecule 2 0.0328263
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0324784
PTK2 protein tyrosine kinase 2 0.0321503
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.0321198
PARP1 poly (ADP-ribose) polymerase 1 0.0320479
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.0319781
ATM ATM serine/threonine kinase 0.0319141
STIL SCL/TAL1 interrupting locus 0.0316768
KMT2A lysine (K)-specific methyltransferase 2A 0.0316137
RREB1 ras responsive element binding protein 1 0.0315375
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0314767
BSG basigin (Ok blood group) 0.0314008
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0312162
PBK PDZ binding kinase 0.0311884
PHTF2 putative homeodomain transcription factor 2 0.0311745
SEPTIN11 septin 11 0.0310633
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0306878
KDM7A lysine (K)-specific demethylase 7A 0.0305152
MFSD2B major facilitator superfamily domain containing 2B 0.030454
ERBIN erbb2 interacting protein 0.030379
NAP1L4 nucleosome assembly protein 1-like 4 0.0303656
SREBF2 sterol regulatory element binding transcription factor 2 0.0301208
FAM120B family with sequence similarity 120B 0.030111
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.0299203
ADGRE2 adhesion G protein-coupled receptor E2 0.0298563
LRPPRC leucine-rich pentatricopeptide repeat containing 0.029805
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.0297334
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0296235
ZFAND6 zinc finger, AN1-type domain 6 0.029617
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0293667
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0292916
OXSR1 oxidative stress responsive 1 0.0291956
CLOCK clock circadian regulator 0.0291891
PHIP pleckstrin homology domain interacting protein 0.0291499
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 0.0286935
KLHDC10 kelch domain containing 10 0.0286676
SESN1 sestrin 1 0.0279775
RPTOR regulatory associated protein of MTOR, complex 1 0.027801
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.0275484
AKAP9 A kinase (PRKA) anchor protein 9 0.0275161
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.0274735
ATAD2B ATPase family, AAA domain containing 2B 0.0272749
KNL1 kinetochore scaffold 1 0.0271987
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0271486
GYPC glycophorin C (Gerbich blood group) 0.0270302
RYBP RING1 and YY1 binding protein 0.0268994
FAM178B family with sequence similarity 178, member B 0.0268489
XPO7 exportin 7 0.0265422
SRRM1 serine/arginine repetitive matrix 1 0.0265205
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.0264705
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0264612
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0264133
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.02626
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.0262074
FBXO11 F-box protein 11 0.0261119
SLC39A7 solute carrier family 39 (zinc transporter), member 7 0.0260414
CFAP70 cilia and flagella associated protein 70 0.0259803
UBA3 ubiquitin-like modifier activating enzyme 3 0.0259521
BST2 bone marrow stromal cell antigen 2 0.025894
VTA1 vesicle (multivesicular body) trafficking 1 0.0258266
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0258059
FLOT1 flotillin 1 0.0257671
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.0257288
ZFPM2 zinc finger protein, FOG family member 2 0.0257276
ARID3B AT rich interactive domain 3B (BRIGHT-like) 0.0256667
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0255951
FOXK1 forkhead box K1 0.0255909
SSB Sjogren syndrome antigen B (autoantigen La) 0.0254669
TRAK2 trafficking protein, kinesin binding 2 0.0253538
KLHL22 kelch-like family member 22 0.0253391
GON4L gon-4-like (C. elegans) 0.0251732
EXOC6 exocyst complex component 6 0.0250895
SOS1 son of sevenless homolog 1 (Drosophila) 0.0250336
SON SON DNA binding protein 0.0249767
STRBP spermatid perinuclear RNA binding protein 0.0248297
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.024709
ADGRB3 adhesion G protein-coupled receptor B3 0.0246613
CELF2 CUGBP, Elav-like family member 2 0.0245667
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0244939
LYRM4 LYR motif containing 4 0.024368
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.0243181
KDM2A lysine (K)-specific demethylase 2A 0.024306
KANSL3 KAT8 regulatory NSL complex subunit 3 0.0242858
PPP4R3B protein phosphatase 4 regulatory subunit 3B 0.024082
CHML choroideremia-like (Rab escort protein 2) 0.0240802
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0238735
CLSTN1 calsyntenin 1 0.0238431
C6ORF89 chromosome 6 open reading frame 89 0.0238372
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0238231
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0238213
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.0237739
PGK1 phosphoglycerate kinase 1 0.0237562
KLHL5 kelch-like family member 5 0.0237508
EVL Enah/Vasp-like 0.0236972
RFX7 regulatory factor X, 7 0.0236836
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.023603
CREB1 cAMP responsive element binding protein 1 0.0235289
NUP62 nucleoporin 62kDa 0.0234344
RBBP6 retinoblastoma binding protein 6 0.0233935
STARD3 StAR-related lipid transfer (START) domain containing 3 0.0233834
CHD1L chromodomain helicase DNA binding protein 1-like 0.0233787
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.0233085
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.0232768
MTDH metadherin 0.0232514
GNL1 guanine nucleotide binding protein-like 1 0.0232177
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0231893
DTNBP1 dystrobrevin binding protein 1 0.0231662
TTC27 tetratricopeptide repeat domain 27 0.0230225
SNX25 sorting nexin 25 0.0229489
MINDY3 MINDY lysine 48 deubiquitinase 3 0.0229231
LRP12 low density lipoprotein receptor-related protein 12 0.0228798
UBAC1 UBA domain containing 1 0.022862
MGST3 microsomal glutathione S-transferase 3 0.022778
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.022774
RBM19 RNA binding motif protein 19 0.0227149
TRIM44 tripartite motif containing 44 0.0226026
JUP junction plakoglobin 0.0225899
NSD2 nuclear receptor binding SET domain protein 2 0.0225438
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.0224544
NBEAL1 neurobeachin-like 1 0.0224059
ARTN artemin 0.0223038
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.0222769
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0222538
RPS27A ribosomal protein S27a 0.0222227
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.022176
CALU calumenin 0.0221696
RPS19 ribosomal protein S19 0.0221385
PKP4 plakophilin 4 0.0221245
RPSA ribosomal protein SA 0.0220825
CCNF cyclin F 0.0220375
MCM3AP minichromosome maintenance complex component 3 associated protein 0.0219942
MSMO1 methylsterol monooxygenase 1 0.0219313
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.02185
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.0217652
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0217635
EP400 E1A binding protein p400 0.0217468
POU2F1 POU class 2 homeobox 1 0.0217203
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.0216396
SMC6 structural maintenance of chromosomes 6 0.021639
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.0216303
KIF18A kinesin family member 18A 0.0216174
ITSN2 intersectin 2 0.021603
DHCR24 24-dehydrocholesterol reductase 0.0215787
NCOA1 nuclear receptor coactivator 1 0.0215651
ARF1 ADP-ribosylation factor 1 0.0215277
MACF1 microtubule-actin crosslinking factor 1 0.0213819
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0213544
ACTN4 actinin, alpha 4 0.0213363
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.0211827
MBTD1 mbt domain containing 1 0.021176
KIF1B kinesin family member 1B 0.0211431
COX6C cytochrome c oxidase subunit VIc 0.0211188
ZDHHC3 zinc finger, DHHC-type containing 3 0.0211092
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0210754
TRIM33 tripartite motif containing 33 0.0210719
SNRNP48 small nuclear ribonucleoprotein 48kDa (U11/U12) 0.0210618
TMEM131 transmembrane protein 131 0.0210453
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 0.0210431
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.0210389
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.0210234
KHDC4 KH domain containing 4, pre-mRNA splicing factor 0.0210137
ZBTB20 zinc finger and BTB domain containing 20 0.0210054
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.0209761
CLASP2 cytoplasmic linker associated protein 2 0.020933
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 0.0209297
CD44 CD44 molecule (Indian blood group) 0.020858
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0207673
TRIM37 tripartite motif containing 37 0.0207214
RDX radixin 0.0206991
NOL10 nucleolar protein 10 0.0206887
PRRC2C proline-rich coiled-coil 2C 0.0206884
ACER3 alkaline ceramidase 3 0.0206771
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.0206279
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0206192
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0206134
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0205382
MICU1 mitochondrial calcium uptake 1 0.0205331
ASPH aspartate beta-hydroxylase 0.0204883
HPCAL1 hippocalcin-like 1 0.0204822
SET SET nuclear proto-oncogene 0.0204319
INO80 INO80 complex subunit 0.0204158
ELOVL6 ELOVL fatty acid elongase 6 0.0203844
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.0203833
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0203247
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.0202421
ACVR1 activin A receptor, type I 0.0201597
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0201452
CCDC32 coiled-coil domain containing 32 0.0200771
GSTK1 glutathione S-transferase kappa 1 0.0200461
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.0200368
TRIM38 tripartite motif containing 38 0.020025
FYCO1 FYVE and coiled-coil domain containing 1 0.0200166
PCNT pericentrin 0.0200157
SRSF11 serine/arginine-rich splicing factor 11 0.0200112
ZC3H13 zinc finger CCCH-type containing 13 0.0199484
USP33 ubiquitin specific peptidase 33 0.0199416
NCOA6 nuclear receptor coactivator 6 0.019934
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0199157
OXNAD1 oxidoreductase NAD-binding domain containing 1 0.0198755
SREK1IP1 SREK1-interacting protein 1 0.0198475
PFN1 profilin 1 0.0197916
BCAS3 breast carcinoma amplified sequence 3 0.0197555
RSU1 Ras suppressor protein 1 0.0197469
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0197415
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.0196555
RBM28 RNA binding motif protein 28 0.0195938
MYH9 myosin, heavy chain 9, non-muscle 0.0195868
TJP1 tight junction protein 1 0.0195669
XPO6 exportin 6 0.0195516
CIZ1 CDKN1A interacting zinc finger protein 1 0.0194802
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.0194576
ADIPOR2 adiponectin receptor 2 0.0194508
BLTP3B bridge-like lipid transfer protein family member 3B 0.0194445
KIAA1586 KIAA1586 0.0194438
NUDCD3 NudC domain containing 3 0.0194243
RNF213 ring finger protein 213 0.0194011
DAZAP2 DAZ associated protein 2 0.019364
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.0193413
TRPS1 trichorhinophalangeal syndrome I 0.0193171
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0193169
ASCC2 activating signal cointegrator 1 complex subunit 2 0.0193139
RSL1D1 ribosomal L1 domain containing 1 0.0192649
NFIA nuclear factor I/A 0.0191796
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.0191751
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0191697
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.01902
THADA thyroid adenoma associated 0.0189868
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.0189266
RPS5 ribosomal protein S5 0.0189194
MYO1D myosin ID 0.0189136
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.0188276
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0188209
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0188156
CLCC1 chloride channel CLIC-like 1 0.018702
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0186993
GIGYF2 GRB10 interacting GYF protein 2 0.0186907
TBC1D22A TBC1 domain family, member 22A 0.0186858
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0186761
LATS1 large tumor suppressor kinase 1 0.0186402
RPL35 ribosomal protein L35 0.0186256
TMEM168 transmembrane protein 168 0.0186011
BTF3L4 basic transcription factor 3-like 4 0.0185946
WAC WW domain containing adaptor with coiled-coil 0.0185606
RIOK3 RIO kinase 3 0.0185559
C9ORF78 chromosome 9 open reading frame 78 0.0185521
ZZZ3 zinc finger, ZZ-type containing 3 0.0185405
PALB2 partner and localizer of BRCA2 0.0185359
SPPL2A signal peptide peptidase like 2A 0.0184934
NES nestin 0.0184788
TMEM273 transmembrane protein 273 0.0184552
EMC7 ER membrane protein complex subunit 7 0.0184199
FAM193A family with sequence similarity 193, member A 0.0184169
CD63 CD63 molecule 0.0182566
FOXRED2 FAD-dependent oxidoreductase domain containing 2 0.0182297
MYADM myeloid-associated differentiation marker 0.0181876
CS citrate synthase 0.0181724
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0181586
TOPBP1 topoisomerase (DNA) II binding protein 1 0.0181327
ZNF124 zinc finger protein 124 0.0181153
RPS2 ribosomal protein S2 0.0181089
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 0.0181079
SMAP2 small ArfGAP2 0.0180667
NUSAP1 nucleolar and spindle associated protein 1 0.0180561
FOXJ3 forkhead box J3 0.01804
CWC22 CWC22 spliceosome-associated protein 0.0180223
NAV1 neuron navigator 1 0.0180112
NCK2 NCK adaptor protein 2 0.0180073
CCNT1 cyclin T1 0.0179982
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.0179708
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0179618
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0179566
ESYT1 extended synaptotagmin-like protein 1 0.0179404
TUSC3 tumor suppressor candidate 3 0.0179001
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.0178863
ZNF83 zinc finger protein 83 0.0178756
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0178602
BBLN bublin coiled coil protein 0.017837
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.0178082
TMCO1 transmembrane and coiled-coil domains 1 0.0177898
RAB1A RAB1A, member RAS oncogene family 0.0177867
NBPF11 neuroblastoma breakpoint family, member 11 0.0177584
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.0176836
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.0176827
DMD dystrophin 0.0176782
MCM3 minichromosome maintenance complex component 3 0.0176631
RNF145 ring finger protein 145 0.0176396
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0176203
TMEM59 transmembrane protein 59 0.0176025
ITPK1 inositol-tetrakisphosphate 1-kinase 0.0175942
SNAP23 synaptosomal-associated protein, 23kDa 0.0175724
KIFAP3 kinesin-associated protein 3 0.0175644
COPG2 coatomer protein complex, subunit gamma 2 0.0175502
MIGA1 mitoguardin 1 0.0174567
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.0174354
PHLDB3 pleckstrin homology-like domain, family B, member 3 0.0174133
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.0173514
IPO7 importin 7 0.0173374
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.0173362
FAM78A family with sequence similarity 78, member A 0.0173115
VARS1 valyl-tRNA synthetase 1 0.0173007
AAGAB alpha- and gamma-adaptin binding protein 0.017289
SASS6 spindle assembly 6 homolog (C. elegans) 0.0172697
DPF3 D4, zinc and double PHD fingers, family 3 0.0172569
IQGAP2 IQ motif containing GTPase activating protein 2 0.0172503
MYO18A myosin XVIIIA 0.0172059
CLASP1 cytoplasmic linker associated protein 1 0.0171909
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 0.0171305
WDR12 WD repeat domain 12 0.0170696
STK40 serine/threonine kinase 40 0.0170407
TBC1D32 TBC1 domain family, member 32 0.0170358
SCAF8 SR-related CTD-associated factor 8 0.0170316
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.0170135
CHPT1 choline phosphotransferase 1 0.0169968
HSPA8 heat shock 70kDa protein 8 0.0169964
WDR33 WD repeat domain 33 0.0169849
POLK polymerase (DNA directed) kappa 0.0169745
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0169564
HPS1 Hermansky-Pudlak syndrome 1 0.0169537
NONO non-POU domain containing, octamer-binding 0.0169263
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.0169257
SCYL2 SCY1-like 2 (S. cerevisiae) 0.0168637
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.0168157
COL26A1 collagen, type XXVI, alpha 1 0.0168131
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0167855
LONP1 lon peptidase 1, mitochondrial 0.0167578
LMO4 LIM domain only 4 0.016719
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0167074
ODR4 odr-4 GPCR localization factor homolog 0.0166847
PDS5B PDS5 cohesin associated factor B 0.0166787
DEPDC5 DEP domain containing 5 0.0166571
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0166486
PCBP2 poly(rC) binding protein 2 0.0166167
PIBF1 progesterone immunomodulatory binding factor 1 0.0166035
ATAD5 ATPase family, AAA domain containing 5 0.0165474
ABHD18 abhydrolase domain containing 18 0.0165082
TACC1 transforming, acidic coiled-coil containing protein 1 0.016475
RINT1 RAD50 interactor 1 0.0164657
RPL10A ribosomal protein L10a 0.0164484
AP1B1 adaptor-related protein complex 1, beta 1 subunit 0.016423
PCSK9 proprotein convertase subtilisin/kexin type 9 0.0163959
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0163938
METTL5 methyltransferase like 5 0.0163751
MELK maternal embryonic leucine zipper kinase 0.0163556
PRDM2 PR domain containing 2, with ZNF domain 0.0163296
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0163108
REST RE1-silencing transcription factor 0.0162666
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.016265
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0162622
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.0162505
GMEB1 glucocorticoid modulatory element binding protein 1 0.0162138
ARF4 ADP-ribosylation factor 4 0.0161849
FASTKD1 FAST kinase domains 1 0.0161701
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.0161692
BRWD1 bromodomain and WD repeat domain containing 1 0.0161667
FAM20B family with sequence similarity 20, member B 0.016158
LARP4 La ribonucleoprotein domain family, member 4 0.0161377
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0161263
RPS9 ribosomal protein S9 0.0160923
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.016072
RFWD3 ring finger and WD repeat domain 3 0.0160658
NUCB2 nucleobindin 2 0.016039
BLMH bleomycin hydrolase 0.0160229
MZT2A mitotic spindle organizing protein 2A 0.0160159
RAI14 retinoic acid induced 14 0.0160114
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0160041
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.0159685
NUP153 nucleoporin 153kDa 0.0159499
WDR89 WD repeat domain 89 0.015945
NCAPG non-SMC condensin I complex, subunit G 0.0159344
FKBP11 FK506 binding protein 11, 19 kDa 0.0159123
GPATCH1 G patch domain containing 1 0.0159091
AP3M2 adaptor-related protein complex 3, mu 2 subunit 0.0159058
ZNF346 zinc finger protein 346 0.0159049
WWOX WW domain containing oxidoreductase 0.0158866
ZNF589 zinc finger protein 589 0.0158791
NFE2L2 nuclear factor, erythroid 2-like 2 0.0158755
JPT2 Jupiter microtubule associated homolog 2 0.0158612
TUBA1B tubulin, alpha 1b 0.0157665
RHOBTB3 Rho-related BTB domain containing 3 0.0157161
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.0157139
EIF4B eukaryotic translation initiation factor 4B 0.0157097
SARS2 seryl-tRNA synthetase 2, mitochondrial 0.0156693
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.0156666
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0156591
ACBD3 acyl-CoA binding domain containing 3 0.0156489
LARP4B La ribonucleoprotein domain family, member 4B 0.0156455
ATP5PB ATP synthase peripheral stalk-membrane subunit b 0.0156447
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.0156374
TXK TXK tyrosine kinase 0.01561
CC2D1A coiled-coil and C2 domain containing 1A 0.0155991
P3H1 prolyl 3-hydroxylase 1 0.0155901
CEP89 centrosomal protein 89kDa 0.0155787
ELP2 elongator acetyltransferase complex subunit 2 0.0155389
MCPH1 microcephalin 1 0.0155152
QRICH1 glutamine-rich 1 0.0155061
PCED1B PC-esterase domain containing 1B 0.0154968
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.0154736
HIRA histone cell cycle regulator 0.0154649
ZNF75A zinc finger protein 75a 0.0154526
MAP4 microtubule-associated protein 4 0.0154455
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0154198
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0154172
SLC22A23 solute carrier family 22, member 23 0.0153724
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.0153423
LYPLAL1 lysophospholipase-like 1 0.0153402
GALE UDP-galactose-4-epimerase 0.0153041
SLC9D1 solute carrier family 9 member D1 0.0152883
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.0152872
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0152832
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0152514
CEP162 centrosomal protein 162kDa 0.0152398
PRR14L proline rich 14-like 0.0152078
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 0.0151937
PNKD paroxysmal nonkinesigenic dyskinesia 0.0151902
CCDC138 coiled-coil domain containing 138 0.015182
BOP1 block of proliferation 1 0.0151377
TBC1D4 TBC1 domain family, member 4 0.0151186
TMEM108 transmembrane protein 108 0.0151179
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.015111
TRA2B transformer 2 beta homolog (Drosophila) 0.0151071
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0150949
SLBP stem-loop binding protein 0.01509
KIFC3 kinesin family member C3 0.0150868
HMGB2 high mobility group box 2 0.0150738
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0150614
TOP6BL TOP6B like initiator of meiotic double strand breaks 0.015031
CLYBL citrate lyase beta like 0.0150276

decreased expression

Symbol Name Standardized Value
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.102689
ADGRV1 adhesion G protein-coupled receptor V1 -0.0918251
KRT8 keratin 8, type II -0.0791348
MKI67 marker of proliferation Ki-67 -0.0764946
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0687249
ARHGAP6 Rho GTPase activating protein 6 -0.0687022
PDLIM5 PDZ and LIM domain 5 -0.068327
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0639616
FBXL13 F-box and leucine-rich repeat protein 13 -0.0617687
ZFAND3 zinc finger, AN1-type domain 3 -0.058172
FDPS farnesyl diphosphate synthase -0.0569406
DIAPH1 diaphanous-related formin 1 -0.0530024
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0527846
MEF2C myocyte enhancer factor 2C -0.0520853
KPNB1 karyopherin (importin) beta 1 -0.0514685
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0491665
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0490168
TNIK TRAF2 and NCK interacting kinase -0.0480953
MUSK muscle, skeletal, receptor tyrosine kinase -0.0478903
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0477801
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0477244
NCOA3 nuclear receptor coactivator 3 -0.0466043
ZNF609 zinc finger protein 609 -0.046489
LDLR low density lipoprotein receptor -0.0464693
CCNI cyclin I -0.0456591
ESYT2 extended synaptotagmin-like protein 2 -0.0455034
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.0445006
JARID2 jumonji, AT rich interactive domain 2 -0.0430245
MBNL1 muscleblind-like splicing regulator 1 -0.042959
SRRM2 serine/arginine repetitive matrix 2 -0.0424838
MAML2 mastermind-like 2 (Drosophila) -0.0423208
TAC4 tachykinin 4 (hemokinin) -0.0418167
SGMS1 sphingomyelin synthase 1 -0.0414662
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0413926
RIPOR3 RIPOR family member 3 -0.0400987
NIPBL Nipped-B homolog (Drosophila) -0.0393715
RAP1B RAP1B, member of RAS oncogene family -0.0386562
AFF1 AF4/FMR2 family, member 1 -0.0385204
METTL8 methyltransferase like 8 -0.0379265
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0376448
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0376179
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0367939
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0366821
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0365296
STIM1 stromal interaction molecule 1 -0.0362381
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.0360577
TASOR2 transcription activation suppressor family member 2 -0.035848
RPS6 ribosomal protein S6 -0.0355689
NIBAN1 niban apoptosis regulator 1 -0.0355457
SENP6 SUMO1/sentrin specific peptidase 6 -0.0349119
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0343977
BCL2L1 BCL2-like 1 -0.0343686
PARD3B par-3 family cell polarity regulator beta -0.0340702
STAG2 stromal antigen 2 -0.033873
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0338598
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0336043
NFYC nuclear transcription factor Y, gamma -0.0335911
MBNL2 muscleblind-like splicing regulator 2 -0.0334882
MAGT1 magnesium transporter 1 -0.0334662
NCKAP1 NCK-associated protein 1 -0.0334561
SFPQ splicing factor proline/glutamine-rich -0.033407
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0330917
ANK1 ankyrin 1, erythrocytic -0.0330645
CALR calreticulin -0.032952
EXOC4 exocyst complex component 4 -0.0329037
AFF4 AF4/FMR2 family, member 4 -0.0328724
NUMB numb homolog (Drosophila) -0.0327328
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0324066
CERS6 ceramide synthase 6 -0.0323651
ZEB2 zinc finger E-box binding homeobox 2 -0.0320956
USP15 ubiquitin specific peptidase 15 -0.031904
CPEB1 cytoplasmic polyadenylation element binding protein 1 -0.0317995
LTBP1 latent transforming growth factor beta binding protein 1 -0.0316259
PTH2R parathyroid hormone 2 receptor -0.0314913
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0311702
KMT5B lysine methyltransferase 5B -0.0308571
CCM2 cerebral cavernous malformation 2 -0.0306934
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -0.0304166
AHDC1 AT hook, DNA binding motif, containing 1 -0.0303398
ANGPT1 angiopoietin 1 -0.0303215
GATAD2A GATA zinc finger domain containing 2A -0.0299981
NMT1 N-myristoyltransferase 1 -0.0299571
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0297672
CEP192 centrosomal protein 192kDa -0.029736
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0297194
JAK2 Janus kinase 2 -0.0295676
SCARB1 scavenger receptor class B, member 1 -0.0292807
NPAT nuclear protein, ataxia-telangiectasia locus -0.0291809
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0291129
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0290759
DOCK8 dedicator of cytokinesis 8 -0.0290598
UBN2 ubinuclein 2 -0.0290098
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0289978
CEP85L centrosomal protein 85kDa-like -0.0287698
NUP210 nucleoporin 210kDa -0.0287664
PICALM phosphatidylinositol binding clathrin assembly protein -0.0287662
NDC1 NDC1 transmembrane nucleoporin -0.0287328
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -0.0286902
PHF20 PHD finger protein 20 -0.0286729
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0286176
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0284466
FAM222B family with sequence similarity 222, member B -0.0282776
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0282598
ZMYND8 zinc finger, MYND-type containing 8 -0.0282222
RAB7A RAB7A, member RAS oncogene family -0.0282049
CLINT1 clathrin interactor 1 -0.0281204
CANX calnexin -0.0281201
COASY CoA synthase -0.0281153
RANBP10 RAN binding protein 10 -0.0280387
TTC7B tetratricopeptide repeat domain 7B -0.0280047
SIK3 SIK family kinase 3 -0.0279704
ARID1A AT rich interactive domain 1A (SWI-like) -0.0279474
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0279157
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.0278152
NUP107 nucleoporin 107kDa -0.0277826
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0277653
CAPN2 calpain 2, (m/II) large subunit -0.0277573
RHBDD2 rhomboid domain containing 2 -0.0277276
UBE3D ubiquitin protein ligase E3D -0.0277234
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0276772
RTN4 reticulon 4 -0.0276193
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0275762
PCM1 pericentriolar material 1 -0.0275742
EXT1 exostosin glycosyltransferase 1 -0.0275531
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0275345
PRELID2 PRELI domain containing 2 -0.0275027
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0274648
CORO1C coronin, actin binding protein, 1C -0.0274497
KIAA0319L KIAA0319-like -0.0272817
RSBN1L round spermatid basic protein 1-like -0.027205
CR1L complement component (3b/4b) receptor 1-like -0.0271403
EIF4E eukaryotic translation initiation factor 4E -0.0270697
MARCHF3 membrane associated ring-CH-type finger 3 -0.0270385
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0268901
RPLP2 ribosomal protein, large, P2 -0.0268796
ARHGAP18 Rho GTPase activating protein 18 -0.026668
FBXO28 F-box protein 28 -0.0266431
FLNB filamin B, beta -0.0265066
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0264093
WDR45 WD repeat domain 45 -0.0263311
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -0.0263025
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0262287
PROC protein C (inactivator of coagulation factors Va and VIIIa) -0.0258819
SCFD2 sec1 family domain containing 2 -0.0257536
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0254591
OSBPL9 oxysterol binding protein-like 9 -0.0254247
FOXP1 forkhead box P1 -0.0253133
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.025137
BPTF bromodomain PHD finger transcription factor -0.0251141
PLAGL1 pleiomorphic adenoma gene-like 1 -0.0250121
FHIT fragile histidine triad -0.0249633
ATP5F1B ATP synthase F1 subunit beta -0.0248699
TENM1 teneurin transmembrane protein 1 -0.0248606
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0248356
AAK1 AP2 associated kinase 1 -0.0247769
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0247012
NUDC nudC nuclear distribution protein -0.0246861
ANTXR2 anthrax toxin receptor 2 -0.0244583
SEPTIN6 septin 6 -0.0243132
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.0242678
NIPSNAP2 nipsnap homolog 2 -0.0242361
LMNA lamin A/C -0.0241325
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0240755
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0240558
CSPP1 centrosome and spindle pole associated protein 1 -0.0239875
RHD Rh blood group, D antigen -0.0239207
USP9X ubiquitin specific peptidase 9, X-linked -0.0239114
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -0.023884
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -0.0238585
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0238436
TPCN1 two pore segment channel 1 -0.0237845
MOB1B MOB kinase activator 1B -0.023771
GCLC glutamate-cysteine ligase, catalytic subunit -0.0237686
INSIG1 insulin induced gene 1 -0.0236931
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0236889
LARS1 leucyl-tRNA synthetase 1 -0.0236198
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0234703
MYO3B myosin IIIB -0.0233885
CHD4 chromodomain helicase DNA binding protein 4 -0.0233716
AFG3L2 AFG3-like AAA ATPase 2 -0.0233563
BLM Bloom syndrome, RecQ helicase-like -0.0232948
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0232869
VMP1 vacuole membrane protein 1 -0.0232847
RPL22 ribosomal protein L22 -0.0231723
SZRD1 SUZ RNA binding domain containing 1 -0.0230509
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0230426
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0229995
ZFR zinc finger RNA binding protein -0.0229042
EIF3I eukaryotic translation initiation factor 3, subunit I -0.0228112
PTK2B protein tyrosine kinase 2 beta -0.0227821
LEPROT leptin receptor overlapping transcript -0.0227217
PLCD1 phospholipase C, delta 1 -0.0227021
CDC45 cell division cycle 45 -0.0226488
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.0226322
EFTUD2 elongation factor Tu GTP binding domain containing 2 -0.0225533
GSTP1 glutathione S-transferase pi 1 -0.0224493
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.022446
MED13 mediator complex subunit 13 -0.0224438
CDC25C cell division cycle 25C -0.022407
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.02238
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0223451
ASXL1 additional sex combs like transcriptional regulator 1 -0.0223325
UBN1 ubinuclein 1 -0.0222339
PTPRA protein tyrosine phosphatase, receptor type, A -0.0220852
SERP1 stress-associated endoplasmic reticulum protein 1 -0.022082
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0220582
DENND5A DENN/MADD domain containing 5A -0.0220061
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0220027
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0220022
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.0219695
RPL28 ribosomal protein L28 -0.0218824
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0218267
SLC37A3 solute carrier family 37, member 3 -0.0218204
NUP188 nucleoporin 188kDa -0.0218142
SPAG9 sperm associated antigen 9 -0.0218106
MAP2K1 mitogen-activated protein kinase kinase 1 -0.0217204
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0216831
RPAP2 RNA polymerase II associated protein 2 -0.0216358
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0216352
CERT1 ceramide transporter 1 -0.0216208
ELOVL5 ELOVL fatty acid elongase 5 -0.0215008
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0214923
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0214728
VAC14 Vac14 homolog (S. cerevisiae) -0.0214492
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0213773
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.021374
CDC42SE2 CDC42 small effector 2 -0.0213217
HMGA1 high mobility group AT-hook 1 -0.0212918
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0212858
INTS6 integrator complex subunit 6 -0.0211959
NUP160 nucleoporin 160kDa -0.0211826
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.0211657
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.0211451
CPPED1 calcineurin-like phosphoesterase domain containing 1 -0.0210413
DCAF7 DDB1 and CUL4 associated factor 7 -0.0210376
VPS35L VPS35 endosomal protein sorting factor like -0.0210281
PLEC plectin -0.0210156
WDR44 WD repeat domain 44 -0.0209887
ECSIT ECSIT signalling integrator -0.0209027
NFX1 nuclear transcription factor, X-box binding 1 -0.0208107
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.0207379
CBFB core-binding factor, beta subunit -0.020688
TM9SF3 transmembrane 9 superfamily member 3 -0.0206702
SLC38A1 solute carrier family 38, member 1 -0.0206622
SH3D19 SH3 domain containing 19 -0.0206484
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.0206327
RORA RAR-related orphan receptor A -0.0206089
ZC3H18 zinc finger CCCH-type containing 18 -0.0206089
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0205023
SOS2 son of sevenless homolog 2 (Drosophila) -0.0204884
PRKCB protein kinase C, beta -0.020466
STX8 syntaxin 8 -0.0204209
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.020364
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0202979
GPBP1L1 GC-rich promoter binding protein 1-like 1 -0.0202937
QKI QKI, KH domain containing, RNA binding -0.0201905
RC3H2 ring finger and CCCH-type domains 2 -0.0200917
TRIM24 tripartite motif containing 24 -0.0200569
DPP9 dipeptidyl-peptidase 9 -0.0200449
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0200008
HBE1 hemoglobin, epsilon 1 -0.0199941
TMEM87A transmembrane protein 87A -0.0199668
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0198614
BIRC6 baculoviral IAP repeat containing 6 -0.0197746
RCC1 regulator of chromosome condensation 1 -0.0197661
SBF2 SET binding factor 2 -0.0197645
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0197485
DNM2 dynamin 2 -0.0197192
DNAAF9 dynein axonemal assembly factor 9 -0.0197127
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -0.0197109
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0196845
TFDP1 transcription factor Dp-1 -0.0195692
SYNJ1 synaptojanin 1 -0.019567
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0195587
MED27 mediator complex subunit 27 -0.0195223
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -0.0194618
NMRAL1 NmrA-like family domain containing 1 -0.0194385
RFC2 replication factor C (activator 1) 2, 40kDa -0.0193621
DHCR7 7-dehydrocholesterol reductase -0.0193464
MEIOB meiosis specific with OB domains -0.0192725
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.0192631
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -0.019231
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0192271
NCAPG2 non-SMC condensin II complex, subunit G2 -0.0191361
REPS1 RALBP1 associated Eps domain containing 1 -0.0191266
KATNBL1 katanin p80 subunit B-like 1 -0.0191216
RCOR3 REST corepressor 3 -0.0191177
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -0.0190716
NSUN4 NOP2/Sun domain family, member 4 -0.0190598
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.0189585
TM9SF4 transmembrane 9 superfamily protein member 4 -0.0189552
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0189079
SEC24D SEC24 family member D -0.018879
ODF2 outer dense fiber of sperm tails 2 -0.0187694
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -0.0187583
SRP72 signal recognition particle 72kDa -0.0187577
CTBP2 C-terminal binding protein 2 -0.018747
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0187406
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.0187191
SKP1 S-phase kinase-associated protein 1 -0.0187124
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa -0.0186098
NOL9 nucleolar protein 9 -0.0185614
RAD23A RAD23 homolog A (S. cerevisiae) -0.0185086
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.0184595
NOL11 nucleolar protein 11 -0.0184583
ERP44 endoplasmic reticulum protein 44 -0.0184564
EYA3 EYA transcriptional coactivator and phosphatase 3 -0.0184076
KIAA0232 KIAA0232 -0.0183638
TUBD1 tubulin, delta 1 -0.0183434
S100PBP S100P binding protein -0.0183039
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.0183026
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0182857
SEC24A SEC24 family member A -0.0182676
RACK1 receptor for activated C kinase 1 -0.0182552
SOGA1 suppressor of glucose, autophagy associated 1 -0.0181848
GNPAT glyceronephosphate O-acyltransferase -0.0181518
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.018133
KANK2 KN motif and ankyrin repeat domains 2 -0.0181102
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -0.0181019
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -0.0180914
ASF1B anti-silencing function 1B histone chaperone -0.0180663
UBXN4 UBX domain protein 4 -0.0180636
MAP7 microtubule-associated protein 7 -0.0180581
CARD8 caspase recruitment domain family, member 8 -0.0180259
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.01801
TULP3 tubby like protein 3 -0.0179996
LCOR ligand dependent nuclear receptor corepressor -0.0179886
IPO9 importin 9 -0.0179789
AKAP8 A kinase (PRKA) anchor protein 8 -0.0179515
BRCA1 breast cancer 1, early onset -0.0179505
ZCCHC10 zinc finger, CCHC domain containing 10 -0.0179435
LMBR1 limb development membrane protein 1 -0.0179054
PRNP prion protein -0.0178788
DSG2 desmoglein 2 -0.0178774
PFDN2 prefoldin subunit 2 -0.0178274
ZC3HC1 zinc finger, C3HC-type containing 1 -0.0178225
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -0.017807
PKM pyruvate kinase, muscle -0.0178054
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.0178041
ARHGAP11A Rho GTPase activating protein 11A -0.0178035
NSUN6 NOP2/Sun domain family, member 6 -0.0177712
RAD9A RAD9 homolog A (S. pombe) -0.0177663
CHLSN cholesin -0.0176822
IGFBP4 insulin-like growth factor binding protein 4 -0.0176508
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0176346
TBL1X transducin (beta)-like 1X-linked -0.017622
KIF14 kinesin family member 14 -0.0175883
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0175066
MPZL1 myelin protein zero-like 1 -0.0174851
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0174708
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0174567
OSBPL8 oxysterol binding protein-like 8 -0.0174405
ZWILCH zwilch kinetochore protein -0.0174354
LTN1 listerin E3 ubiquitin protein ligase 1 -0.0174309
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0174307
LCORL ligand dependent nuclear receptor corepressor-like -0.0173906
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0173704
PROS1 protein S (alpha) -0.0173385
SCML2 sex comb on midleg-like 2 (Drosophila) -0.0173325
TP53BP1 tumor protein p53 binding protein 1 -0.0172782
CHD9 chromodomain helicase DNA binding protein 9 -0.0172281
CFAP161 cilia and flagella associated protein 161 -0.0172127
ANXA2 annexin A2 -0.0171964
BLTP3A bridge-like lipid transfer protein family member 3A -0.017177
WARS1 tryptophanyl-tRNA synthetase 1 -0.0171363
COPE coatomer protein complex, subunit epsilon -0.0171288
ATG10 autophagy related 10 -0.0170835
LRP10 low density lipoprotein receptor-related protein 10 -0.0170588
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.0170572
NRF1 nuclear respiratory factor 1 -0.016954
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0169073
CYTH3 cytohesin 3 -0.0168883
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0168839
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -0.0168788
STK24 serine/threonine kinase 24 -0.0168767
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0168677
MRPS5 mitochondrial ribosomal protein S5 -0.0168492
CDK13 cyclin-dependent kinase 13 -0.0168068
ZNF3 zinc finger protein 3 -0.0167976
AMOTL1 angiomotin like 1 -0.0167757
CDK12 cyclin-dependent kinase 12 -0.0167662
SKA2 spindle and kinetochore associated complex subunit 2 -0.016745
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0167293
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -0.0166795
PTPRS protein tyrosine phosphatase, receptor type, S -0.0166761
BCOR BCL6 corepressor -0.0166252
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 -0.0165934
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0165724
ANKRD10 ankyrin repeat domain 10 -0.0165621
ATG4C autophagy related 4C, cysteine peptidase -0.0165584
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0165225
STIP1 stress-induced phosphoprotein 1 -0.0165205
NUMA1 nuclear mitotic apparatus protein 1 -0.0165155
TMEM181 transmembrane protein 181 -0.0165104
H3C4 H3 clustered histone 4 -0.0165041
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0164598
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -0.0164443
CFDP1 craniofacial development protein 1 -0.0164373
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.0164237
TPX2 TPX2, microtubule-associated -0.0164069
AUH AU RNA binding protein/enoyl-CoA hydratase -0.0163801
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -0.0163363
KDM5B lysine (K)-specific demethylase 5B -0.0162803
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.0162736
FBXL17 F-box and leucine-rich repeat protein 17 -0.0162503
EMC8 ER membrane protein complex subunit 8 -0.0162363
MRPS35 mitochondrial ribosomal protein S35 -0.0162232
RNF149 ring finger protein 149 -0.0161922
AK1 adenylate kinase 1 -0.0161147
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0161111
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -0.0160924
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -0.0160815
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0160594
QSER1 glutamine and serine rich 1 -0.0160395
IREB2 iron-responsive element binding protein 2 -0.0160228
SCAND3 SCAN domain containing 3 -0.016013
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -0.0159621
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0159601
OSTC oligosaccharyltransferase complex subunit (non-catalytic) -0.0159593
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0159568
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0159517
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0159491
WWC2 WW and C2 domain containing 2 -0.015943
RAB5A RAB5A, member RAS oncogene family -0.0159019
FBXW11 F-box and WD repeat domain containing 11 -0.015901
TGFBR1 transforming growth factor, beta receptor 1 -0.0158929
USP54 ubiquitin specific peptidase 54 -0.0158592
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0158511
METTL16 methyltransferase like 16 -0.015819
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -0.0157822
RCL1 RNA terminal phosphate cyclase-like 1 -0.0157312
NGLY1 N-glycanase 1 -0.0156958
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0156938
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.0156866
KNTC1 kinetochore associated 1 -0.0156736
CCDC18 coiled-coil domain containing 18 -0.0156494
USP20 ubiquitin specific peptidase 20 -0.0156479
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -0.0156398
MSL2 male-specific lethal 2 homolog (Drosophila) -0.0156359
NPC1 Niemann-Pick disease, type C1 -0.0156218
TANGO6 transport and golgi organization 6 homolog (Drosophila) -0.0155841
LNPEP leucyl/cystinyl aminopeptidase -0.0155712
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.0155699
GARRE1 granule associated Rac and RHOG effector 1 -0.0155683
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0155557
COG4 component of oligomeric golgi complex 4 -0.0155448
UBE2Z ubiquitin-conjugating enzyme E2Z -0.015521
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0155065
GRK3 G protein-coupled receptor kinase 3 -0.0155047
DRC8 dynein regulatory complex subunit 8 -0.0154941
SAR1B secretion associated, Ras related GTPase 1B -0.015483
CHEK2 checkpoint kinase 2 -0.0154694
TACC3 transforming, acidic coiled-coil containing protein 3 -0.0154506
FAM117B family with sequence similarity 117, member B -0.0154315
ATXN7L1 ataxin 7-like 1 -0.0154216
PARD6B par-6 family cell polarity regulator beta -0.0153998
GFM1 G elongation factor, mitochondrial 1 -0.0153926
IL6ST interleukin 6 signal transducer -0.0153921
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0153814
KDM1A lysine (K)-specific demethylase 1A -0.0153519
NOL4L nucleolar protein 4-like -0.0153322
NPEPPS aminopeptidase puromycin sensitive -0.0153098
AMBRA1 autophagy/beclin-1 regulator 1 -0.015259
ACYP2 acylphosphatase 2, muscle type -0.0152589
ZFYVE28 zinc finger, FYVE domain containing 28 -0.0152522
BLVRB biliverdin reductase B -0.015207
SNX2 sorting nexin 2 -0.0151279
RBM15 RNA binding motif protein 15 -0.0151111
RNASE12 ribonuclease, RNase A family, 12 (non-active) -0.015099
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0150979
TMEM39B transmembrane protein 39B -0.0150804
KIF5B kinesin family member 5B -0.0150408
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0150105
TMEM116 transmembrane protein 116 -0.014989
CLIP1 CAP-GLY domain containing linker protein 1 -0.014989
CLIC4 chloride intracellular channel 4 -0.0149856
DGCR2 DiGeorge syndrome critical region gene 2 -0.0149809
TMEM131L transmembrane 131 like -0.0149741
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.0149351
LSG1 large 60S subunit nuclear export GTPase 1 -0.0149222
ASCC1 activating signal cointegrator 1 complex subunit 1 -0.0149031
FAM234A family with sequence similarity 234 member A -0.0148979
RPL12 ribosomal protein L12 -0.0148874
OXCT1 3-oxoacid CoA transferase 1 -0.0148802
RPL7A ribosomal protein L7a -0.0148771
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0148675
FXR1 fragile X mental retardation, autosomal homolog 1 -0.0148453
GAB3 GRB2-associated binding protein 3 -0.0148339
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0148218
SNRPG small nuclear ribonucleoprotein polypeptide G -0.014745
CD58 CD58 molecule -0.0147358
MTCH2 mitochondrial carrier 2 -0.0146996
DOP1A DOP1 leucine zipper like protein A -0.0146987
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0146703
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.014645
MTREX Mtr4 exosome RNA helicase -0.0146408
TRAPPC8 trafficking protein particle complex 8 -0.0145975
RPS7 ribosomal protein S7 -0.0145974
KIF18B kinesin family member 18B -0.0145769
LRRC8B leucine rich repeat containing 8 family, member B -0.014561