K562_Valproic acid sodium salt_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 100nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_Valproic acid sodium salt_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCB protein kinase C, beta 0.155381
PICALM phosphatidylinositol binding clathrin assembly protein 0.100258
MAML2 mastermind-like 2 (Drosophila) 0.0917799
CHD4 chromodomain helicase DNA binding protein 4 0.0907308
ZCCHC7 zinc finger, CCHC domain containing 7 0.0903196
PRKCA protein kinase C, alpha 0.0826257
USP34 ubiquitin specific peptidase 34 0.069259
RORA RAR-related orphan receptor A 0.0594426
PDS5A PDS5 cohesin associated factor A 0.0574084
FAM13A family with sequence similarity 13, member A 0.0570792
CNKSR3 CNKSR family member 3 0.0561698
SIK3 SIK family kinase 3 0.0536516
CENPF centromere protein F, 350/400kDa 0.0533501
EYA3 EYA transcriptional coactivator and phosphatase 3 0.0522826
LARP4B La ribonucleoprotein domain family, member 4B 0.0513408
KDM5B lysine (K)-specific demethylase 5B 0.0511917
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.048508
RUNX1 runt-related transcription factor 1 0.0479567
ARHGAP6 Rho GTPase activating protein 6 0.0470788
KRT18 keratin 18, type I 0.0458904
CAMKMT calmodulin-lysine N-methyltransferase 0.0454067
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0452697
TBL1X transducin (beta)-like 1X-linked 0.0440743
XPO7 exportin 7 0.044028
NCAM2 neural cell adhesion molecule 2 0.0439106
FGF13 fibroblast growth factor 13 0.0436164
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0431869
EXPH5 exophilin 5 0.0423331
ZFPM2 zinc finger protein, FOG family member 2 0.0422731
RYBP RING1 and YY1 binding protein 0.0419432
DOCK9 dedicator of cytokinesis 9 0.0413749
MARCHF7 membrane associated ring-CH-type finger 7 0.0411214
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0409336
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0403108
DCHS2 dachsous cadherin-related 2 0.0401842
HELZ helicase with zinc finger 0.040125
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0400447
RSRP1 arginine/serine-rich protein 1 0.0396516
BMP2K BMP2 inducible kinase 0.0390359
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0384917
TIAM2 T-cell lymphoma invasion and metastasis 2 0.0381703
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0378958
KIF13A kinesin family member 13A 0.0377216
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0375531
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.0374728
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0373636
PRR11 proline rich 11 0.0373509
MED27 mediator complex subunit 27 0.0371767
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0370588
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0370549
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0361806
SND1 staphylococcal nuclease and tudor domain containing 1 0.0360647
MAP2K5 mitogen-activated protein kinase kinase 5 0.03598
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0358529
SLTM SAFB-like, transcription modulator 0.0358511
PUS7 pseudouridylate synthase 7 (putative) 0.0358153
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0355677
WAC WW domain containing adaptor with coiled-coil 0.035411
INVS inversin 0.0353814
IARS1 isoleucyl-tRNA synthetase 1 0.0352208
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.0350113
BCAS3 breast carcinoma amplified sequence 3 0.0347677
ANK1 ankyrin 1, erythrocytic 0.0343748
ACIN1 apoptotic chromatin condensation inducer 1 0.034184
DYNC2I1 dynein 2 intermediate chain 1 0.0337859
PRELID2 PRELI domain containing 2 0.0337755
NIPBL Nipped-B homolog (Drosophila) 0.0336882
USP48 ubiquitin specific peptidase 48 0.0334279
H4C3 H4 clustered histone 3 0.0330246
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.0329774
KCTD20 potassium channel tetramerization domain containing 20 0.0329562
ATP11B ATPase, class VI, type 11B 0.0328402
PHGDH phosphoglycerate dehydrogenase 0.0328182
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0327486
GSE1 Gse1 coiled-coil protein 0.0327112
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0323165
METTL15 methyltransferase like 15 0.0322785
PARD3B par-3 family cell polarity regulator beta 0.032036
RAB10 RAB10, member RAS oncogene family 0.031888
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0316768
FAM222B family with sequence similarity 222, member B 0.0316037
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.0316024
CCM2 cerebral cavernous malformation 2 0.0312293
CELF1 CUGBP, Elav-like family member 1 0.0312113
KIF2C kinesin family member 2C 0.0311604
OXSR1 oxidative stress responsive 1 0.0309446
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0306405
NCOR1 nuclear receptor corepressor 1 0.0305938
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.030497
PRPF4B pre-mRNA processing factor 4B 0.030448
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0304405
DIAPH3 diaphanous-related formin 3 0.0303041
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0302993
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0302501
SGMS1 sphingomyelin synthase 1 0.0302458
SPIRE1 spire-type actin nucleation factor 1 0.0299604
MAN2A1 mannosidase, alpha, class 2A, member 1 0.0299168
SCAF8 SR-related CTD-associated factor 8 0.0297977
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0297062
UBXN7 UBX domain protein 7 0.0295597
UBE4B ubiquitination factor E4B 0.0292518
FCHSD2 FCH and double SH3 domains 2 0.0292184
JARID2 jumonji, AT rich interactive domain 2 0.0291777
PACS1 phosphofurin acidic cluster sorting protein 1 0.0288775
SPC25 SPC25, NDC80 kinetochore complex component 0.0288573
DCAF7 DDB1 and CUL4 associated factor 7 0.0287938
ANKRD13C ankyrin repeat domain 13C 0.0287085
SSBP3 single stranded DNA binding protein 3 0.0285565
NKTR natural killer cell triggering receptor 0.0285055
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0284284
ZEB2 zinc finger E-box binding homeobox 2 0.0283976
SLIT2 slit homolog 2 (Drosophila) 0.0282711
FYB1 FYN binding protein 1 0.028256
VEZT vezatin, adherens junctions transmembrane protein 0.0281435
PHTF2 putative homeodomain transcription factor 2 0.0280398
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 0.0280023
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.027931
EXOC4 exocyst complex component 4 0.0278915
CR1L complement component (3b/4b) receptor 1-like 0.027861
AEBP2 AE binding protein 2 0.0277841
EVL Enah/Vasp-like 0.0277196
CBFB core-binding factor, beta subunit 0.0276937
SEPTIN6 septin 6 0.0274889
HDAC4 histone deacetylase 4 0.0274766
RBM39 RNA binding motif protein 39 0.0274764
ATP11C ATPase, class VI, type 11C 0.0274437
FBXL17 F-box and leucine-rich repeat protein 17 0.027317
ARL15 ADP-ribosylation factor-like 15 0.0273078
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.0272896
RHD Rh blood group, D antigen 0.027273
NAT10 N-acetyltransferase 10 (GCN5-related) 0.0272505
RREB1 ras responsive element binding protein 1 0.0272438
CIZ1 CDKN1A interacting zinc finger protein 1 0.0272318
NECTIN2 nectin cell adhesion molecule 2 0.0270651
ADGRL1 adhesion G protein-coupled receptor L1 0.0269963
CUX1 cut-like homeobox 1 0.0267051
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 0.0264983
CRPPA CDP-L-ribitol pyrophosphorylase A 0.0264835
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0264662
EXOC6 exocyst complex component 6 0.026201
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 0.0261982
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0261162
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0260678
SLA2 Src-like-adaptor 2 0.0260225
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0259969
FBL fibrillarin 0.025897
EIF3I eukaryotic translation initiation factor 3, subunit I 0.0257527
TBC1D14 TBC1 domain family, member 14 0.0257064
TMEM245 transmembrane protein 245 0.0254194
SBF2 SET binding factor 2 0.025399
SERGEF secretion regulating guanine nucleotide exchange factor 0.0253764
RAI14 retinoic acid induced 14 0.0252162
SAMD4B sterile alpha motif domain containing 4B 0.0250898
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0250291
TRPS1 trichorhinophalangeal syndrome I 0.0250024
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.024956
TEC tec protein tyrosine kinase 0.0249385
PCDH9 protocadherin 9 0.0248737
CDK13 cyclin-dependent kinase 13 0.0247152
ANKRD11 ankyrin repeat domain 11 0.0246892
RAD51B RAD51 paralog B 0.0246651
MOB1B MOB kinase activator 1B 0.0246533
SMG6 SMG6 nonsense mediated mRNA decay factor 0.0246364
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.0246252
MFSD2B major facilitator superfamily domain containing 2B 0.0245872
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0245674
LATS1 large tumor suppressor kinase 1 0.0244637
DENND4C DENN/MADD domain containing 4C 0.0244393
RPAP3 RNA polymerase II associated protein 3 0.0243974
DYNC2I2 dynein 2 intermediate chain 2 0.0243675
SACK1H scaffolding CK1 anchoring protein H 0.024222
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.0242127
STAG2 stromal antigen 2 0.0241695
CEP152 centrosomal protein 152kDa 0.0241135
CENPP centromere protein P 0.0240829
ANXA11 annexin A11 0.0239265
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 0.023885
CREG1 cellular repressor of E1A-stimulated genes 1 0.0238055
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0237506
SMYD3 SET and MYND domain containing 3 0.0236735
RNF115 ring finger protein 115 0.0236163
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0235994
H2AZ2 H2A.Z variant histone 2 0.0235616
RPL13A ribosomal protein L13a 0.0235592
KIAA0319L KIAA0319-like 0.0234725
NCOA6 nuclear receptor coactivator 6 0.0234136
TP53BP2 tumor protein p53 binding protein 2 0.0233625
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0232257
RLF rearranged L-myc fusion 0.0232097
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.0231933
TBK1 TANK-binding kinase 1 0.0231872
TXLNA taxilin alpha 0.0231736
CLTCL1 clathrin, heavy chain-like 1 0.0231697
RPS2 ribosomal protein S2 0.0230966
FYCO1 FYVE and coiled-coil domain containing 1 0.0230631
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.0230622
IQCK IQ motif containing K 0.0230172
SDCCAG8 serologically defined colon cancer antigen 8 0.0227631
SPG11 spastic paraplegia 11 (autosomal recessive) 0.0226204
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0224699
FAM168B family with sequence similarity 168, member B 0.0223323
FBXO11 F-box protein 11 0.0223317
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.0223241
BUB3 BUB3 mitotic checkpoint protein 0.0222756
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0222735
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.0222063
ZNF518A zinc finger protein 518A 0.0222043
ATG7 autophagy related 7 0.0221733
MMP12 matrix metallopeptidase 12 0.0221468
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0221375
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.0219993
NPEPPS aminopeptidase puromycin sensitive 0.0219878
NCAPD3 non-SMC condensin II complex, subunit D3 0.0219758
RPL14 ribosomal protein L14 0.021942
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0218994
MRPS10 mitochondrial ribosomal protein S10 0.0218835
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.0218582
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0218152
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 0.0217593
CCDC6 coiled-coil domain containing 6 0.0217458
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.0216856
PDLIM5 PDZ and LIM domain 5 0.0216402
EIF3B eukaryotic translation initiation factor 3, subunit B 0.021606
MRPL19 mitochondrial ribosomal protein L19 0.0215939
ATE1 arginyltransferase 1 0.021585
TM9SF3 transmembrane 9 superfamily member 3 0.0215634
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0215347
TMOD1 tropomodulin 1 0.0214417
COP1 COP1 E3 ubiquitin ligase 0.0214312
IPO9 importin 9 0.0214251
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.0214042
FTO fat mass and obesity associated 0.0213536
NRIP1 nuclear receptor interacting protein 1 0.0213183
OLA1 Obg-like ATPase 1 0.0211347
RBSN rabenosyn, RAB effector 0.0211043
XPO4 exportin 4 0.0210953
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0210623
RABGAP1L RAB GTPase activating protein 1-like 0.0210353
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0209535
GTF2I general transcription factor IIi 0.0209078
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.0208698
SCLT1 sodium channel and clathrin linker 1 0.0208548
MPZL1 myelin protein zero-like 1 0.0208503
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0208226
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.0207918
DENND1B DENN/MADD domain containing 1B 0.0207897
TSLIG3B tRNA splicing ligase complex subunit 3B 0.0207675
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0207569
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0207514
PGPEP1 pyroglutamyl-peptidase I 0.0207199
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0206801
PBRM1 polybromo 1 0.0206717
MAP7D1 MAP7 domain containing 1 0.0205135
NEK7 NIMA-related kinase 7 0.0205055
EGF epidermal growth factor 0.0204974
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0204626
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0204249
SCAI suppressor of cancer cell invasion 0.020324
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0202589
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.0202143
FUBP1 far upstream element (FUSE) binding protein 1 0.0202045
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.0201974
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.0201911
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.0201757
ZNF562 zinc finger protein 562 0.0201386
RBBP6 retinoblastoma binding protein 6 0.0199993
RPL23A ribosomal protein L23a 0.0199821
PCDHB16 protocadherin beta 16 0.0199675
FSCN1 fascin actin-bundling protein 1 0.0199498
H1-10 H1.10 linker histone 0.0199456
RB1CC1 RB1-inducible coiled-coil 1 0.0199292
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.0199252
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.0199046
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.0199038
VCP valosin containing protein 0.0198712
RBM19 RNA binding motif protein 19 0.0198156
NUP62 nucleoporin 62kDa 0.0197318
SYNJ2 synaptojanin 2 0.0197007
RBM5 RNA binding motif protein 5 0.0196826
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.019646
COG7 component of oligomeric golgi complex 7 0.0196349
HDAC3 histone deacetylase 3 0.0195888
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.0195607
SENP5 SUMO1/sentrin specific peptidase 5 0.0194616
ZNF292 zinc finger protein 292 0.0194599
WDFY1 WD repeat and FYVE domain containing 1 0.0194391
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0194222
CCAR1 cell division cycle and apoptosis regulator 1 0.0194166
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0194137
CFAP161 cilia and flagella associated protein 161 0.0193964
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.019293
PFN1 profilin 1 0.0192616
FOXP1 forkhead box P1 0.0192197
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0192087
EVI5 ecotropic viral integration site 5 0.0191398
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.01912
GON4L gon-4-like (C. elegans) 0.0191064
UBQLN1 ubiquilin 1 0.0190878
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.019064
AGO2 argonaute RISC catalytic component 2 0.0190609
P3H1 prolyl 3-hydroxylase 1 0.0190329
TRAP1 TNF receptor-associated protein 1 0.0189318
ZNF431 zinc finger protein 431 0.0188559
PHIP pleckstrin homology domain interacting protein 0.0187855
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 0.0186666
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0185985
STAT5A signal transducer and activator of transcription 5A 0.0185441
MCM3AP minichromosome maintenance complex component 3 associated protein 0.018528
GLTP glycolipid transfer protein 0.0185045
CMC4 C-x(9)-C motif containing 4 0.0184819
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0184792
DMTF1 cyclin D binding myb-like transcription factor 1 0.0184588
EIF3D eukaryotic translation initiation factor 3, subunit D 0.0184043
SNX25 sorting nexin 25 0.0183991
ZNF160 zinc finger protein 160 0.0183969
SORT1 sortilin 1 0.0183873
SLF1 SMC5-SMC6 complex localization factor 1 0.0183622
RSBN1 round spermatid basic protein 1 0.0182662
CLIP2 CAP-GLY domain containing linker protein 2 0.0182331
ATF6 activating transcription factor 6 0.0182188
ZGRF1 zinc finger, GRF-type containing 1 0.0181959
MARCKSL1 MARCKS-like 1 0.0181939
SPPL2A signal peptide peptidase like 2A 0.0181922
HDAC5 histone deacetylase 5 0.0181875
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.0181843
SEPTIN7 septin 7 0.0181642
RAD23B RAD23 homolog B (S. cerevisiae) 0.018135
STRIP2 striatin interacting protein 2 0.0180831
CHD1 chromodomain helicase DNA binding protein 1 0.0180751
SLC35E1 solute carrier family 35, member E1 0.0180691
ZNF586 zinc finger protein 586 0.0180548
KIF18A kinesin family member 18A 0.0180003
ACBD6 acyl-CoA binding domain containing 6 0.0179495
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0179369
EYS eyes shut homolog (Drosophila) 0.0179312
MFAP1 microfibrillar-associated protein 1 0.0179209
LMNA lamin A/C 0.0179051
IGSF1 immunoglobulin superfamily, member 1 0.0178794
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 0.0178775
TP53RK TP53 regulating kinase 0.0178315
AGO3 argonaute RISC catalytic component 3 0.0178249
SEC24B SEC24 family member B 0.0177959
XPO1 exportin 1 0.0176815
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 0.0176691
KIFBP kinesin family binding protein 0.0176645
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 0.0176556
CSMD1 CUB and Sushi multiple domains 1 0.0176552
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0176192
SEC31A SEC31 homolog A (S. cerevisiae) 0.0176055
SPAG9 sperm associated antigen 9 0.0175896
BAIAP2L1 BAI1-associated protein 2-like 1 0.0175769
INTS1 integrator complex subunit 1 0.0175557
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.0175468
CFAP299 cilia and flagella associated protein 299 0.017495
UBAP2 ubiquitin associated protein 2 0.0174631
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0174359
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0173878
WWOX WW domain containing oxidoreductase 0.0173813
KIAA1328 KIAA1328 0.0173608
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.0173419
MRPL47 mitochondrial ribosomal protein L47 0.0173414
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.017276
SLC39A11 solute carrier family 39, member 11 0.0171981
PODXL2 podocalyxin-like 2 0.0171799
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.0171477
ABI1 abl-interactor 1 0.0171331
NMT1 N-myristoyltransferase 1 0.0171089
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0170926
USP32 ubiquitin specific peptidase 32 0.0170878
ARL5A ADP-ribosylation factor-like 5A 0.0170493
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.017043
ATRN attractin 0.0170283
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0170243
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0169762
STRN striatin, calmodulin binding protein 0.0169022
KNL1 kinetochore scaffold 1 0.0169003
CEP128 centrosomal protein 128kDa 0.0168946
UBIAD1 UbiA prenyltransferase domain containing 1 0.0168801
FAM174B family with sequence similarity 174, member B 0.016875
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 0.0168275
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.0167966
ADGRE2 adhesion G protein-coupled receptor E2 0.0167518
MITF microphthalmia-associated transcription factor 0.0167168
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.0167012
DMXL1 Dmx-like 1 0.0166847
CLTC clathrin, heavy chain (Hc) 0.0166231
AFF4 AF4/FMR2 family, member 4 0.0166168
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 0.0166098
ZC3H6 zinc finger CCCH-type containing 6 0.0165306
FOSL1 FOS-like antigen 1 0.0165255
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.0164948
NUP98 nucleoporin 98kDa 0.0164793
ZFYVE28 zinc finger, FYVE domain containing 28 0.0164594
NFE2L2 nuclear factor, erythroid 2-like 2 0.0164509
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0164492
CCDC150 coiled-coil domain containing 150 0.0164372
PARD6B par-6 family cell polarity regulator beta 0.0164151
ZNF721 zinc finger protein 721 0.016404
CLSPN claspin 0.0163844
STXBP3 syntaxin binding protein 3 0.0163664
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0163362
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0163292
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 0.0163104
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 0.0163023
UBAC2 UBA domain containing 2 0.0163006
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.0162916
ANTXR2 anthrax toxin receptor 2 0.0162583
SLC35D4 solute carrier family 35 member D4 0.0162582
USP42 ubiquitin specific peptidase 42 0.0162572
INTS7 integrator complex subunit 7 0.0162501
ZNF148 zinc finger protein 148 0.0162158
DEXI Dexi homolog (mouse) 0.0162119
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.016211
ACVR1 activin A receptor, type I 0.0161794
VDAC2 voltage-dependent anion channel 2 0.0161415
SLC38A9 solute carrier family 38, member 9 0.0161199
TTBK2 tau tubulin kinase 2 0.0160518
SMC4 structural maintenance of chromosomes 4 0.0160225
TMTC3 transmembrane and tetratricopeptide repeat containing 3 0.0160077
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0160043
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.0160001
FBXO9 F-box protein 9 0.0159705
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 0.0159149
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.0158787
GLMN glomulin, FKBP associated protein 0.0158528
RPGR retinitis pigmentosa GTPase regulator 0.0158285
MYEOV myeloma overexpressed 0.0158164
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.01577
HIPK2 homeodomain interacting protein kinase 2 0.0157547
CD58 CD58 molecule 0.0157496
SEM1 SEM1 26S proteasome subunit 0.0157288
CPED1 cadherin-like and PC-esterase domain containing 1 0.0157157
ZMYM2 zinc finger, MYM-type 2 0.0156995
GAB2 GRB2-associated binding protein 2 0.0156849
PARP1 poly (ADP-ribose) polymerase 1 0.0156655
GOLGA4 golgin A4 0.0156362
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.0156338
PRPF3 pre-mRNA processing factor 3 0.0156264
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 0.0156104
RNF214 ring finger protein 214 0.0156048
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0155721
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.0155438
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.0154843
STK24 serine/threonine kinase 24 0.0154734
MIGA2 mitoguardin 2 0.0154651
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0154455
EXOC2 exocyst complex component 2 0.0154341
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.0153698
ANGPT1 angiopoietin 1 0.015368
DKC1 dyskeratosis congenita 1, dyskerin 0.0153667
SIN3A SIN3 transcription regulator family member A 0.0153452
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0153219
NADK2 NAD kinase 2, mitochondrial 0.0153136
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0153055
DHDDS dehydrodolichyl diphosphate synthase 0.0153036
MED13L mediator complex subunit 13-like 0.0152988
KIF5B kinesin family member 5B 0.0152581
SUCO SUN domain containing ossification factor 0.0152449
CCDC69 coiled-coil domain containing 69 0.0152241
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0151716
TRIP12 thyroid hormone receptor interactor 12 0.0151658
ASPH aspartate beta-hydroxylase 0.0151276
PPP1R12C protein phosphatase 1, regulatory subunit 12C 0.0151139
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.0151101
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.0151086
TMX4 thioredoxin-related transmembrane protein 4 0.0150346
LDAH lipid droplet associated hydrolase 0.0150292
SLX4 SLX4 structure-specific endonuclease subunit 0.0150262
WDR43 WD repeat domain 43 0.0150169
NBAS neuroblastoma amplified sequence 0.0149997
RC3H2 ring finger and CCCH-type domains 2 0.0149977
TMEM165 transmembrane protein 165 0.0149854
ABI2 abl-interactor 2 0.0149774
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0149758
GATA2 GATA binding protein 2 0.0149612
FARSA phenylalanyl-tRNA synthetase, alpha subunit 0.0149317
ZYG11A zyg-11 family member A, cell cycle regulator 0.0149229
DCTN4 dynactin 4 (p62) 0.0149204
ZFP36L2 ZFP36 ring finger protein-like 2 0.0149074
DOCK11 dedicator of cytokinesis 11 0.0148885
COPS4 COP9 signalosome subunit 4 0.0148536
MRPS5 mitochondrial ribosomal protein S5 0.0148233
KLF16 Kruppel-like factor 16 0.0148115
PDAP1 PDGFA associated protein 1 0.0147988
MARK2 MAP/microtubule affinity-regulating kinase 2 0.014793
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.0147708
FKBP11 FK506 binding protein 11, 19 kDa 0.0147667
PML promyelocytic leukemia 0.0147549
MVD mevalonate (diphospho) decarboxylase 0.0147412
PANK3 pantothenate kinase 3 0.0147252
ZMPSTE24 zinc metallopeptidase STE24 0.0147228
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.0146468
MARCHF8 membrane associated ring-CH-type finger 8 0.0146259
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0146256
WDR76 WD repeat domain 76 0.0146231
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.014619
ARHGAP24 Rho GTPase activating protein 24 0.0146168
CEP250 centrosomal protein 250kDa 0.0146149
GRID1 glutamate receptor, ionotropic, delta 1 0.0146001
TRAF3 TNF receptor-associated factor 3 0.0145995

decreased expression

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase -0.0932199
ZMYND8 zinc finger, MYND-type containing 8 -0.0823119
VCL vinculin -0.0789889
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.073285
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0720081
FNDC3B fibronectin type III domain containing 3B -0.0682126
ACACA acetyl-CoA carboxylase alpha -0.0629736
MYO1D myosin ID -0.0629025
FLNA filamin A, alpha -0.0603417
PPP1R9B protein phosphatase 1, regulatory subunit 9B -0.0590297
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0575972
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0562654
PKN2 protein kinase N2 -0.0552079
MAPK1 mitogen-activated protein kinase 1 -0.053446
NUP214 nucleoporin 214kDa -0.0532189
GPC5 glypican 5 -0.051454
SCARB1 scavenger receptor class B, member 1 -0.0505142
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0503372
RPS8 ribosomal protein S8 -0.0479874
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -0.0466684
TTC28 tetratricopeptide repeat domain 28 -0.046269
ACTN4 actinin, alpha 4 -0.0454159
MBNL1 muscleblind-like splicing regulator 1 -0.0450201
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0448968
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0448358
FBXL13 F-box and leucine-rich repeat protein 13 -0.0445239
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0444465
CMIP c-Maf inducing protein -0.043908
TCF12 transcription factor 12 -0.0435598
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0428629
RBMX RNA binding motif protein, X-linked -0.0422365
HPCAL1 hippocalcin-like 1 -0.0417651
DOCK8 dedicator of cytokinesis 8 -0.0409975
ETF1 eukaryotic translation termination factor 1 -0.0407497
VMP1 vacuole membrane protein 1 -0.0402407
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0397355
ATXN7L1 ataxin 7-like 1 -0.0394111
BSG basigin (Ok blood group) -0.038366
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0380026
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0379367
STAU1 staufen double-stranded RNA binding protein 1 -0.0376595
SRSF4 serine/arginine-rich splicing factor 4 -0.0374968
STAT5B signal transducer and activator of transcription 5B -0.0373715
MACF1 microtubule-actin crosslinking factor 1 -0.0369581
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0367751
RTN3 reticulon 3 -0.0364423
DCAF6 DDB1 and CUL4 associated factor 6 -0.0363411
SETD5 SET domain containing 5 -0.0362425
MSN moesin -0.0360288
RAP1B RAP1B, member of RAS oncogene family -0.0359354
GLUL glutamate-ammonia ligase -0.0356473
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0350458
PLCL1 phospholipase C-like 1 -0.0350159
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.0348679
AKAP9 A kinase (PRKA) anchor protein 9 -0.0347823
PDIA3 protein disulfide isomerase family A, member 3 -0.0347812
CALU calumenin -0.0346187
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.034294
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0342849
MTOR mechanistic target of rapamycin (serine/threonine kinase) -0.0342143
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -0.0341344
CCDC88A coiled-coil domain containing 88A -0.0340404
CSPP1 centrosome and spindle pole associated protein 1 -0.0335785
SOS1 son of sevenless homolog 1 (Drosophila) -0.0333741
FHIT fragile histidine triad -0.0329623
RPLP0 ribosomal protein, large, P0 -0.0328109
ENO1 enolase 1, (alpha) -0.0327121
FBXW11 F-box and WD repeat domain containing 11 -0.0325433
RBM15 RNA binding motif protein 15 -0.0323455
CUL1 cullin 1 -0.0320525
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0319954
LTBP1 latent transforming growth factor beta binding protein 1 -0.0318224
HEATR1 HEAT repeat containing 1 -0.0317164
PRRC2C proline-rich coiled-coil 2C -0.0316771
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0313608
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0312518
CCDC47 coiled-coil domain containing 47 -0.0310967
SERBP1 SERPINE1 mRNA binding protein 1 -0.0310621
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.03099
IPO7 importin 7 -0.0306677
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0305739
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0300998
RPS5 ribosomal protein S5 -0.0298902
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.029282
NASP nuclear autoantigenic sperm protein (histone-binding) -0.029078
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -0.0289938
LDHA lactate dehydrogenase A -0.0288661
FANCI Fanconi anemia, complementation group I -0.0288284
CDC14A cell division cycle 14A -0.0286858
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0284096
SRRM2 serine/arginine repetitive matrix 2 -0.0282934
OCIAD1 OCIA domain containing 1 -0.028111
SENP6 SUMO1/sentrin specific peptidase 6 -0.0280503
NUP153 nucleoporin 153kDa -0.0279784
CCDC57 coiled-coil domain containing 57 -0.0279311
TRIM27 tripartite motif containing 27 -0.0277227
NUP210 nucleoporin 210kDa -0.0277114
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0276591
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0275889
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0273659
HBG2 hemoglobin, gamma G -0.0273186
TUBB tubulin, beta class I -0.0271558
KDM2B lysine (K)-specific demethylase 2B -0.0271334
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -0.0271105
ADGRB3 adhesion G protein-coupled receptor B3 -0.0269801
BCL2L1 BCL2-like 1 -0.0269079
SRP72 signal recognition particle 72kDa -0.0268887
ZNF638 zinc finger protein 638 -0.0267525
RPN2 ribophorin II -0.0266923
UBE3C ubiquitin protein ligase E3C -0.0265738
CTSD cathepsin D -0.0265283
RNF4 ring finger protein 4 -0.0262825
DGCR2 DiGeorge syndrome critical region gene 2 -0.0262295
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0262059
SMC1A structural maintenance of chromosomes 1A -0.026193
BRWD1 bromodomain and WD repeat domain containing 1 -0.0261546
SFPQ splicing factor proline/glutamine-rich -0.0261519
PRRC2B proline-rich coiled-coil 2B -0.0261157
GSK3B glycogen synthase kinase 3 beta -0.0260644
RPL37 ribosomal protein L37 -0.0260501
RBM28 RNA binding motif protein 28 -0.0260443
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0259861
YME1L1 YME1-like 1 ATPase -0.025959
RFX7 regulatory factor X, 7 -0.0257393
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.0257203
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.0257074
AVL9 AVL9 homolog (S. cerevisiase) -0.0256751
LAMP2 lysosomal-associated membrane protein 2 -0.0255158
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.025422
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.0254077
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0254039
RNF217 ring finger protein 217 -0.0254004
USP6NL USP6 N-terminal like -0.0253485
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.0253235
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0252937
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0252794
TASOR2 transcription activation suppressor family member 2 -0.0252723
CCDC91 coiled-coil domain containing 91 -0.0252671
RPS18 ribosomal protein S18 -0.0250981
CAPRIN1 cell cycle associated protein 1 -0.0250721
PRKCSH protein kinase C substrate 80K-H -0.0249078
FANCD2 Fanconi anemia, complementation group D2 -0.024798
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0247716
PPP1R10 protein phosphatase 1, regulatory subunit 10 -0.0247398
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.0245969
FRS2 fibroblast growth factor receptor substrate 2 -0.024444
CCNI cyclin I -0.0243612
PHKB phosphorylase kinase, beta -0.0242982
HBZ hemoglobin, zeta -0.0242638
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0242237
SOGA1 suppressor of glucose, autophagy associated 1 -0.024215
TAOK1 TAO kinase 1 -0.0242059
H2AC6 H2A clustered histone 6 -0.024204
MRPS25 mitochondrial ribosomal protein S25 -0.0241764
DROSHA drosha, ribonuclease type III -0.0241678
DHCR7 7-dehydrocholesterol reductase -0.0241367
STIP1 stress-induced phosphoprotein 1 -0.0241234
GPBP1L1 GC-rich promoter binding protein 1-like 1 -0.0241169
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0241074
INSIG1 insulin induced gene 1 -0.0240401
KMT2A lysine (K)-specific methyltransferase 2A -0.0239874
C11ORF58 chromosome 11 open reading frame 58 -0.0238774
ARHGAP21 Rho GTPase activating protein 21 -0.0238771
USP9X ubiquitin specific peptidase 9, X-linked -0.0238521
CEP170 centrosomal protein 170kDa -0.0238281
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.0237106
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -0.0236807
MARCHF6 membrane associated ring-CH-type finger 6 -0.0236774
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0235558
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -0.0235304
POM121 POM121 transmembrane nucleoporin -0.0235059
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.0234569
SCFD1 sec1 family domain containing 1 -0.0234474
GNAS GNAS complex locus -0.0233859
RNF216 ring finger protein 216 -0.0233667
CENPE centromere protein E, 312kDa -0.0233611
AATF apoptosis antagonizing transcription factor -0.0233514
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0233333
AGO1 argonaute RISC catalytic component 1 -0.0233262
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -0.0232078
RBM33 RNA binding motif protein 33 -0.023059
KNTC1 kinetochore associated 1 -0.0230205
ERI1 exoribonuclease 1 -0.0229942
BICRAL BICRA like chromatin remodeling complex associated protein -0.0229848
GLG1 golgi glycoprotein 1 -0.0229356
WAPL WAPL cohesin release factor -0.022914
CEP295 centrosomal protein 295kDa -0.022818
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0228074
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0226949
PARK7 parkinson protein 7 -0.0226498
PEX14 peroxisomal biogenesis factor 14 -0.0226315
NFYC nuclear transcription factor Y, gamma -0.0226162
TMEM181 transmembrane protein 181 -0.0224865
PARN poly(A)-specific ribonuclease -0.022478
INTS4 integrator complex subunit 4 -0.0224581
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.022418
HDAC8 histone deacetylase 8 -0.0224143
N4BP2 NEDD4 binding protein 2 -0.0223925
TOP2B topoisomerase (DNA) II beta 180kDa -0.0223158
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0222815
NUCB1 nucleobindin 1 -0.0222436
EIF4E eukaryotic translation initiation factor 4E -0.0222158
CDC123 cell division cycle 123 -0.0222059
RHOBTB3 Rho-related BTB domain containing 3 -0.0221234
TOX4 TOX high mobility group box family member 4 -0.0219851
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0219154
TET1 tet methylcytosine dioxygenase 1 -0.0218218
BTBD1 BTB (POZ) domain containing 1 -0.0218093
SLC37A3 solute carrier family 37, member 3 -0.0217964
LIN9 lin-9 DREAM MuvB core complex component -0.0217575
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -0.0217525
DEK DEK proto-oncogene -0.0215252
TRIM24 tripartite motif containing 24 -0.0214355
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -0.0214204
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0214027
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -0.0213746
EMP3 epithelial membrane protein 3 -0.0213708
LARP1B La ribonucleoprotein domain family, member 1B -0.0213379
NCOR2 nuclear receptor corepressor 2 -0.0212108
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0211051
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0210535
ARHGAP11B Rho GTPase activating protein 11B -0.0209471
TBCE tubulin folding cofactor E -0.0209329
MCM4 minichromosome maintenance complex component 4 -0.0209208
QSER1 glutamine and serine rich 1 -0.0209124
PTBP2 polypyrimidine tract binding protein 2 -0.0208587
KDM4B lysine (K)-specific demethylase 4B -0.0208246
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0208054
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -0.0207323
TRA2A transformer 2 alpha homolog (Drosophila) -0.0206466
TNPO3 transportin 3 -0.0206425
PXDN peroxidasin -0.0205928
GAN gigaxonin -0.0205543
ZFAND3 zinc finger, AN1-type domain 3 -0.020527
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.0205246
CLSTN1 calsyntenin 1 -0.0204882
SKIC3 SKI3 subunit of superkiller complex -0.0204855
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0204752
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0204261
TTC7B tetratricopeptide repeat domain 7B -0.0203359
C6ORF62 chromosome 6 open reading frame 62 -0.0203354
MEF2C myocyte enhancer factor 2C -0.0202628
RAD18 RAD18 E3 ubiquitin protein ligase -0.0202496
RPS16 ribosomal protein S16 -0.0202298
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.0202059
PCCA propionyl CoA carboxylase, alpha polypeptide -0.0201499
TANK TRAF family member-associated NFKB activator -0.0200952
LMLN leishmanolysin-like (metallopeptidase M8 family) -0.0199693
TAOK3 TAO kinase 3 -0.0199644
DCAF10 DDB1 and CUL4 associated factor 10 -0.0199322
ATP5F1D ATP synthase F1 subunit delta -0.0199183
RANBP10 RAN binding protein 10 -0.0198873
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0198606
RPAP2 RNA polymerase II associated protein 2 -0.0198254
LRRC8B leucine rich repeat containing 8 family, member B -0.0196715
MAPK8 mitogen-activated protein kinase 8 -0.0196511
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -0.0195797
CHD8 chromodomain helicase DNA binding protein 8 -0.01951
SRRM1 serine/arginine repetitive matrix 1 -0.0195037
EIF3M eukaryotic translation initiation factor 3, subunit M -0.0194788
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0194573
ADD3 adducin 3 (gamma) -0.0194501
SRSF11 serine/arginine-rich splicing factor 11 -0.0193783
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.0193777
UNC13D unc-13 homolog D (C. elegans) -0.0193682
MMS22L MMS22-like, DNA repair protein -0.0193336
GPBP1 GC-rich promoter binding protein 1 -0.0193124
SEC16A SEC16 homolog A (S. cerevisiae) -0.0192808
PCM1 pericentriolar material 1 -0.0192722
ATAD2 ATPase family, AAA domain containing 2 -0.0192371
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.019237
RAB7A RAB7A, member RAS oncogene family -0.0191916
TBC1D22B TBC1 domain family, member 22B -0.0191368
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0191313
C6ORF89 chromosome 6 open reading frame 89 -0.0191155
GOLIM4 golgi integral membrane protein 4 -0.0190958
POLK polymerase (DNA directed) kappa -0.0189686
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0189329
ANKRD12 ankyrin repeat domain 12 -0.0189224
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.0188976
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0188934
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0188899
LTAP1 lipid transport auxiliary protein 1 -0.0188684
ELOVL5 ELOVL fatty acid elongase 5 -0.0187805
RPL32 ribosomal protein L32 -0.0187703
MAGT1 magnesium transporter 1 -0.0187284
GOLGB1 golgin B1 -0.0187143
RANBP9 RAN binding protein 9 -0.0187085
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0186749
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.0186248
ADIPOR2 adiponectin receptor 2 -0.0186238
SUMF2 sulfatase modifying factor 2 -0.0184435
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0184184
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -0.0184058
ATAD3A ATPase family, AAA domain containing 3A -0.0183911
SUCLG1 succinate-CoA ligase, alpha subunit -0.0183443
ENOSF1 enolase superfamily member 1 -0.0183052
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0182713
CORO1C coronin, actin binding protein, 1C -0.0182662
KDM6A lysine (K)-specific demethylase 6A -0.0181832
PAIP1 poly(A) binding protein interacting protein 1 -0.0181731
HSPB1 heat shock 27kDa protein 1 -0.0181334
GLCCI1 glucocorticoid induced 1 -0.0181122
SLF2 SMC5-SMC6 complex localization factor 2 -0.0181094
RPS29 ribosomal protein S29 -0.0180903
DHCR24 24-dehydrocholesterol reductase -0.0180808
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -0.0180791
MRPS27 mitochondrial ribosomal protein S27 -0.0180553
ADCY7 adenylate cyclase 7 -0.0180514
FAM193B family with sequence similarity 193, member B -0.0180454
TMSB10 thymosin beta 10 -0.0180387
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0180093
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -0.0180035
GSTP1 glutathione S-transferase pi 1 -0.0179939
EIF1 eukaryotic translation initiation factor 1 -0.0179889
TRIM37 tripartite motif containing 37 -0.0179055
TXNRD2 thioredoxin reductase 2 -0.0178894
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.0178731
CLASP2 cytoplasmic linker associated protein 2 -0.0178258
COMT catechol-O-methyltransferase -0.0177874
PFKP phosphofructokinase, platelet -0.0177654
IFT88 intraflagellar transport 88 -0.0176415
MCM8 minichromosome maintenance complex component 8 -0.0176251
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0176236
SLC38A1 solute carrier family 38, member 1 -0.0176116
XYLB xylulokinase homolog (H. influenzae) -0.0176079
CANX calnexin -0.0175656
KMT5A lysine methyltransferase 5A -0.0175297
STK40 serine/threonine kinase 40 -0.0175212
CNTRL centriolin -0.0175104
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -0.0174939
NDC1 NDC1 transmembrane nucleoporin -0.0174937
ZNF207 zinc finger protein 207 -0.017467
SEC63 SEC63 homolog (S. cerevisiae) -0.017454
HDAC2 histone deacetylase 2 -0.0174502
ABHD2 abhydrolase domain containing 2 -0.0173502
ARHGAP17 Rho GTPase activating protein 17 -0.0172834
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0172833
CFDP1 craniofacial development protein 1 -0.0172819
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -0.0171841
NGLY1 N-glycanase 1 -0.017158
CDC42SE2 CDC42 small effector 2 -0.0171403
AKAP11 A kinase (PRKA) anchor protein 11 -0.0171382
RCOR1 REST corepressor 1 -0.0171027
SMC5 structural maintenance of chromosomes 5 -0.0170486
CFH complement factor H -0.0170443
SNAP29 synaptosomal-associated protein, 29kDa -0.0170399
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -0.0170392
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.0170187
ZNF121 zinc finger protein 121 -0.0170096
GPATCH4 G patch domain containing 4 -0.016983
TRAPPC12 trafficking protein particle complex 12 -0.0169436
NMU neuromedin U -0.0169392
ZMYM4 zinc finger, MYM-type 4 -0.0169155
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -0.0169151
UVRAG UV radiation resistance associated -0.0169065
RHBDD2 rhomboid domain containing 2 -0.0168727
ZNF451 zinc finger protein 451 -0.0168654
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.016816
UBB ubiquitin B -0.0168068
KIF14 kinesin family member 14 -0.0167716
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0167567
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0167371
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.0167357
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0167174
HBG1 hemoglobin, gamma A -0.0167107
GSTO1 glutathione S-transferase omega 1 -0.0167083
MCM7 minichromosome maintenance complex component 7 -0.0166962
ZNF146 zinc finger protein 146 -0.016686
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.0166782
CREB5 cAMP responsive element binding protein 5 -0.0166103
PREPL prolyl endopeptidase-like -0.0165703
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 -0.0165418
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0165299
PLCD1 phospholipase C, delta 1 -0.0165097
PGM3 phosphoglucomutase 3 -0.0164727
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -0.0164542
TRIM38 tripartite motif containing 38 -0.0164421
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.016392
CEP135 centrosomal protein 135kDa -0.0163703
PTPRC protein tyrosine phosphatase, receptor type, C -0.016358
RHOA ras homolog family member A -0.0163514
NCALD neurocalcin delta -0.0163457
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -0.0163341
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -0.0163339
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0163273
SERP1 stress-associated endoplasmic reticulum protein 1 -0.0163269
TUFM Tu translation elongation factor, mitochondrial -0.0163233
PWWP2A PWWP domain containing 2A -0.0162866
ATXN10 ataxin 10 -0.0162644
AMBRA1 autophagy/beclin-1 regulator 1 -0.0162435
DNAH14 dynein, axonemal, heavy chain 14 -0.0162104
PDIA5 protein disulfide isomerase family A, member 5 -0.0162017
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0161834
SNRPC small nuclear ribonucleoprotein polypeptide C -0.0160973
SRPK2 SRSF protein kinase 2 -0.0160843
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0160481
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D -0.0160342
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0160213
ELOVL6 ELOVL fatty acid elongase 6 -0.0160166
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 -0.01601
WDR27 WD repeat domain 27 -0.0159908
NEMP1 nuclear envelope integral membrane protein 1 -0.0159681
WARS1 tryptophanyl-tRNA synthetase 1 -0.0159116
NRDC nardilysin convertase -0.0159024
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0158989
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.015884
DNM2 dynamin 2 -0.0158438
UBAP2L ubiquitin associated protein 2-like -0.0158278
SAFB scaffold attachment factor B -0.0158152
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0157754
TXNRD1 thioredoxin reductase 1 -0.0156849
EMC1 ER membrane protein complex subunit 1 -0.0156684
GMPS guanine monphosphate synthase -0.0156628
FBXL20 F-box and leucine-rich repeat protein 20 -0.015636
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 -0.0156349
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0156329
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.0155915
BCAP31 B-cell receptor-associated protein 31 -0.015584
EEF2K eukaryotic elongation factor 2 kinase -0.0155807
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0155718
SPTBN2 spectrin, beta, non-erythrocytic 2 -0.0155642
LMBR1 limb development membrane protein 1 -0.0155563
EMC3 ER membrane protein complex subunit 3 -0.0155531
SEC13 SEC13 homolog (S. cerevisiae) -0.0155431
RCL1 RNA terminal phosphate cyclase-like 1 -0.015529
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0154776
VRK1 vaccinia related kinase 1 -0.0154512
PRKN parkin RBR E3 ubiquitin protein ligase -0.015373
METAP1 methionyl aminopeptidase 1 -0.0153654
LMNB1 lamin B1 -0.0153619
TBC1D5 TBC1 domain family, member 5 -0.0152992
TRIM28 tripartite motif containing 28 -0.0152879
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.0152876
PKM pyruvate kinase, muscle -0.0152873
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0152798
SCYL2 SCY1-like 2 (S. cerevisiae) -0.0152716
MBTPS1 membrane-bound transcription factor peptidase, site 1 -0.0152309
H1-2 H1.2 linker histone, cluster member -0.0152187
FNIP2 folliculin interacting protein 2 -0.0152182
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0151581
MROH1 maestro heat-like repeat family member 1 -0.0151387
LDHD lactate dehydrogenase D -0.0151087
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0150718
UBAC1 UBA domain containing 1 -0.0150251
AHI1 Abelson helper integration site 1 -0.0150006
FNDC3A fibronectin type III domain containing 3A -0.0149867
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0149521
FAF1 Fas (TNFRSF6) associated factor 1 -0.0149479
R3HDM2 R3H domain containing 2 -0.0149235
TOR1AIP1 torsin A interacting protein 1 -0.0149146
MECR mitochondrial trans-2-enoyl-CoA reductase -0.0148916
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0148714
ESRRB estrogen-related receptor beta -0.014857
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 -0.0148146
PPT1 palmitoyl-protein thioesterase 1 -0.0147945
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -0.0147807
MAU2 MAU2 sister chromatid cohesion factor -0.0147782
TUT4 terminal uridylyl transferase 4 -0.0147436
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.0147397
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0147354
JUND jun D proto-oncogene -0.0147307
LETMD1 LETM1 domain containing 1 -0.0147053
ELP4 elongator acetyltransferase complex subunit 4 -0.014705
NKAPD1 NKAP domain containing 1 -0.0147045
ZC3H7B zinc finger CCCH-type containing 7B -0.0146926
NUP93 nucleoporin 93kDa -0.0146432
RPS12 ribosomal protein S12 -0.0146283
MTX2 metaxin 2 -0.0146104
TRAK1 trafficking protein, kinesin binding 1 -0.014596
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 -0.0145952
HMGN1 high mobility group nucleosome binding domain 1 -0.0145893
DBT dihydrolipoamide branched chain transacylase E2 -0.0145343
INTS10 integrator complex subunit 10 -0.0145103
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0144806
TGOLN2 trans-golgi network protein 2 -0.0144761
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0144655
MRPL40 mitochondrial ribosomal protein L40 -0.0144633
MLH1 mutL homolog 1 -0.0144588
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0144302
MCM9 minichromosome maintenance complex component 9 -0.0144203
ATG4C autophagy related 4C, cysteine peptidase -0.0144032
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.0143802
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 -0.0143723
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0143481
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.0142952
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0142837
DDIT4 DNA-damage-inducible transcript 4 -0.0142635
CAPN2 calpain 2, (m/II) large subunit -0.0142593
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0142351
RPLP2 ribosomal protein, large, P2 -0.0142234
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.014223
MPHOSPH9 M-phase phosphoprotein 9 -0.0141979
KMT5B lysine methyltransferase 5B -0.0141774
RPL10A ribosomal protein L10a -0.0141767
DENND1A DENN/MADD domain containing 1A -0.0141563
TRA2B transformer 2 beta homolog (Drosophila) -0.014149
SMAP1 small ArfGAP 1 -0.0141462
DSG2 desmoglein 2 -0.0141453
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -0.0141195