K562_Valproic acid sodium salt_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 10nM perturbation in K562 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the K562_Valproic acid sodium salt_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
SMYD3 SET and MYND domain containing 3 0.130317
ARL15 ADP-ribosylation factor-like 15 0.0971569
FAM13A family with sequence similarity 13, member A 0.0922047
SEC31A SEC31 homolog A (S. cerevisiae) 0.0871482
FNDC3B fibronectin type III domain containing 3B 0.0832603
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0715064
TRPS1 trichorhinophalangeal syndrome I 0.0661298
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.0658828
SORBS1 sorbin and SH3 domain containing 1 0.0620148
CUX1 cut-like homeobox 1 0.0605221
ANO10 anoctamin 10 0.0604129
PARD3B par-3 family cell polarity regulator beta 0.055972
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.0554024
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0536978
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0524943
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.0506349
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.050112
NEBL nebulette 0.0497775
CEP350 centrosomal protein 350kDa 0.0495379
ADGRB3 adhesion G protein-coupled receptor B3 0.0484814
ESYT2 extended synaptotagmin-like protein 2 0.0481335
KIF2A kinesin heavy chain member 2A 0.0464128
BCR breakpoint cluster region 0.0460999
GTF2IRD1 GTF2I repeat domain containing 1 0.0452998
CDC73 cell division cycle 73 0.0447661
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0446415
SRRM1 serine/arginine repetitive matrix 1 0.04399
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0436795
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.043295
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.0429344
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.0427412
CDK19 cyclin-dependent kinase 19 0.0426427
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0424483
GDNF glial cell derived neurotrophic factor 0.04208
RBM33 RNA binding motif protein 33 0.0420283
THOC2 THO complex 2 0.0415189
RSF1 remodeling and spacing factor 1 0.0411564
LTBP1 latent transforming growth factor beta binding protein 1 0.0411141
STRBP spermatid perinuclear RNA binding protein 0.0410081
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0410018
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0407581
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0402373
ZNF652 zinc finger protein 652 0.0392626
PRKCB protein kinase C, beta 0.0391001
ENSA endosulfine alpha 0.0388993
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0387111
HPCAL1 hippocalcin-like 1 0.0380353
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0378598
NCOA1 nuclear receptor coactivator 1 0.0370978
ZDHHC14 zinc finger, DHHC-type containing 14 0.036908
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.0368519
WWOX WW domain containing oxidoreductase 0.0362632
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0359995
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.0356563
COPB1 coatomer protein complex, subunit beta 1 0.0354642
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0351379
ASXL2 additional sex combs like transcriptional regulator 2 0.0348773
POU2F1 POU class 2 homeobox 1 0.034802
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.034531
SIL1 SIL1 nucleotide exchange factor 0.0341012
KMT2C lysine (K)-specific methyltransferase 2C 0.0337347
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0336433
SEPTIN6 septin 6 0.0336074
DMD dystrophin 0.0332947
PRPF4B pre-mRNA processing factor 4B 0.0332452
NIPBL Nipped-B homolog (Drosophila) 0.0332284
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0331906
LIMS1 LIM and senescent cell antigen-like domains 1 0.0330824
SORT1 sortilin 1 0.0330592
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0330231
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0329192
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0328197
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0325739
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0324888
TTC3 tetratricopeptide repeat domain 3 0.032427
NEK7 NIMA-related kinase 7 0.0322329
SENP6 SUMO1/sentrin specific peptidase 6 0.0322068
MBTD1 mbt domain containing 1 0.0320323
NCAM2 neural cell adhesion molecule 2 0.0318407
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0309498
DYNC2I1 dynein 2 intermediate chain 1 0.030908
ORAI2 ORAI calcium release-activated calcium modulator 2 0.0307046
PHF21A PHD finger protein 21A 0.0305857
MPHOSPH9 M-phase phosphoprotein 9 0.0305331
NEK1 NIMA-related kinase 1 0.0302538
MYO1D myosin ID 0.0301354
SUGP2 SURP and G patch domain containing 2 0.0301295
CLCN3 chloride channel, voltage-sensitive 3 0.0299363
COG5 component of oligomeric golgi complex 5 0.0298862
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.0297638
STEAP1B STEAP family member 1B 0.0294047
BCL2L13 BCL2-like 13 (apoptosis facilitator) 0.0293938
TLK1 tousled-like kinase 1 0.0292943
LDHA lactate dehydrogenase A 0.0291592
EZR ezrin 0.0289919
ARID1A AT rich interactive domain 1A (SWI-like) 0.0289351
UBE4B ubiquitination factor E4B 0.0287842
TFRC transferrin receptor 0.0285899
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.0284801
RAB6A RAB6A, member RAS oncogene family 0.0284558
RBMX RNA binding motif protein, X-linked 0.0284076
SCFD2 sec1 family domain containing 2 0.0283725
MYH10 myosin, heavy chain 10, non-muscle 0.0283321
RREB1 ras responsive element binding protein 1 0.0282604
ANK1 ankyrin 1, erythrocytic 0.0281151
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0280088
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0279743
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.0278571
CENPF centromere protein F, 350/400kDa 0.0276527
TRIM56 tripartite motif containing 56 0.0275358
UBAP1 ubiquitin associated protein 1 0.0275059
PKM pyruvate kinase, muscle 0.0274857
RNF217 ring finger protein 217 0.0274828
RBM15 RNA binding motif protein 15 0.0273456
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0273257
SESN1 sestrin 1 0.0273021
ZFAND3 zinc finger, AN1-type domain 3 0.0272247
TPT1 tumor protein, translationally-controlled 1 0.0271793
MACF1 microtubule-actin crosslinking factor 1 0.0271004
WNK1 WNK lysine deficient protein kinase 1 0.0270939
GATAD2A GATA zinc finger domain containing 2A 0.0270842
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.026973
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0266074
ADAM10 ADAM metallopeptidase domain 10 0.0264675
EIF3E eukaryotic translation initiation factor 3, subunit E 0.0264502
USP34 ubiquitin specific peptidase 34 0.026432
SLC25A43 solute carrier family 25, member 43 0.026393
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0263089
TUSC3 tumor suppressor candidate 3 0.0263078
ZNF326 zinc finger protein 326 0.0263026
TBC1D23 TBC1 domain family, member 23 0.0262893
SNX25 sorting nexin 25 0.0262831
ENO1 enolase 1, (alpha) 0.0261922
TBL1X transducin (beta)-like 1X-linked 0.0261184
IGF2R insulin-like growth factor 2 receptor 0.0260979
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0259811
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 0.0259538
CREB3L2 cAMP responsive element binding protein 3-like 2 0.025935
RPL15 ribosomal protein L15 0.0259154
FNBP1 formin binding protein 1 0.0258987
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0257742
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0257709
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0257053
TNRC6A trinucleotide repeat containing 6A 0.0256725
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0255282
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.0254454
ACTG1 actin gamma 1 0.0253835
KEL Kell blood group, metallo-endopeptidase 0.0252943
AFF4 AF4/FMR2 family, member 4 0.0250776
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.0249044
DLG1 discs, large homolog 1 (Drosophila) 0.0248129
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0247788
MAPK1 mitogen-activated protein kinase 1 0.0246961
TNRC18 trinucleotide repeat containing 18 0.0246522
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.024578
RORA RAR-related orphan receptor A 0.0245639
FGF13 fibroblast growth factor 13 0.0245152
AFDN afadin, adherens junction formation factor 0.0244867
MAU2 MAU2 sister chromatid cohesion factor 0.0244592
SIK3 SIK family kinase 3 0.0242485
RSRP1 arginine/serine-rich protein 1 0.0242347
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0242218
TRAF3 TNF receptor-associated factor 3 0.0242136
NFIA nuclear factor I/A 0.0241647
U2SURP U2 snRNP-associated SURP domain containing 0.0240404
STK4 serine/threonine kinase 4 0.0240071
ACVR1 activin A receptor, type I 0.0239686
KDM4C lysine (K)-specific demethylase 4C 0.0239524
KMT2A lysine (K)-specific methyltransferase 2A 0.0238729
SPC25 SPC25, NDC80 kinetochore complex component 0.0238724
SEC24C SEC24 family member C 0.0238512
VEZT vezatin, adherens junctions transmembrane protein 0.023792
DAND5 DAN domain family member 5, BMP antagonist 0.0237452
DPH6 diphthamine biosynthesis 6 0.0236931
TCF12 transcription factor 12 0.0236559
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0236153
DOCK8 dedicator of cytokinesis 8 0.0236113
CDK17 cyclin-dependent kinase 17 0.0235716
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0235601
RNF111 ring finger protein 111 0.0235168
BCL6 B-cell CLL/lymphoma 6 0.0235089
MIA3 melanoma inhibitory activity family, member 3 0.0234608
RAP1B RAP1B, member of RAS oncogene family 0.0234274
CKAP5 cytoskeleton associated protein 5 0.0234256
C17ORF99 chromosome 17 open reading frame 99 0.0234169
SRBD1 S1 RNA binding domain 1 0.0233152
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0231618
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.0231109
ABHD18 abhydrolase domain containing 18 0.0230779
TXNRD1 thioredoxin reductase 1 0.0230457
MTDH metadherin 0.0229442
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.0229327
PGK1 phosphoglycerate kinase 1 0.0229207
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.0228972
ATP5PB ATP synthase peripheral stalk-membrane subunit b 0.0228159
TMEM156 transmembrane protein 156 0.0228038
PRELID2 PRELI domain containing 2 0.0227446
NRXN3 neurexin 3 0.0226768
MAP1B microtubule-associated protein 1B 0.0225926
MAST4 microtubule associated serine/threonine kinase family member 4 0.0224722
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.0224525
ZRANB3 zinc finger, RAN-binding domain containing 3 0.022198
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.022186
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.0221189
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.0221177
MACC1 metastasis associated in colon cancer 1 0.0220707
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0220464
DCLRE1C DNA cross-link repair 1C 0.0220129
PTBP3 polypyrimidine tract binding protein 3 0.0219404
PDE8A phosphodiesterase 8A 0.0219387
MSI2 musashi RNA-binding protein 2 0.0219341
PTK2 protein tyrosine kinase 2 0.0218639
PFN1 profilin 1 0.0218625
KLHL22 kelch-like family member 22 0.0218131
CREB5 cAMP responsive element binding protein 5 0.0217314
PUM3 pumilio RNA binding family member 3 0.0217212
SNX8 sorting nexin 8 0.0217138
CHD9 chromodomain helicase DNA binding protein 9 0.0216158
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.0215841
ZFAND6 zinc finger, AN1-type domain 6 0.0215518
GOLGA8B golgin A8 family, member B 0.0214623
MAPK8 mitogen-activated protein kinase 8 0.0213223
MYEOV myeloma overexpressed 0.0213188
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0212887
ANXA7 annexin A7 0.0212343
RNPC3 RNA-binding region (RNP1, RRM) containing 3 0.021142
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.0210918
PRR16 proline rich 16 0.0210013
NIBAN1 niban apoptosis regulator 1 0.0209843
LUC7L LUC7-like (S. cerevisiae) 0.0209109
SMIM44 small integral membrane protein 44 0.0208676
THAP4 THAP domain containing 4 0.0208631
BRD8 bromodomain containing 8 0.0208432
SNX9 sorting nexin 9 0.0208175
STK38 serine/threonine kinase 38 0.020748
DGKH diacylglycerol kinase, eta 0.0207337
CPOX coproporphyrinogen oxidase 0.0206897
STK24 serine/threonine kinase 24 0.0206887
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0205911
AFF1 AF4/FMR2 family, member 1 0.0204335
NUP210 nucleoporin 210kDa 0.0204327
CR1L complement component (3b/4b) receptor 1-like 0.0204234
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.020412
FAM193B family with sequence similarity 193, member B 0.0203999
BCLAF1 BCL2-associated transcription factor 1 0.0203999
VEGFA vascular endothelial growth factor A 0.02036
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.0203202
PTRH2 peptidyl-tRNA hydrolase 2 0.0203107
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0201937
USP15 ubiquitin specific peptidase 15 0.0201805
OLA1 Obg-like ATPase 1 0.0201729
DST dystonin 0.0201633
MARCHF6 membrane associated ring-CH-type finger 6 0.0201563
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 0.0200805
SQSTM1 sequestosome 1 0.0199323
RABL6 RAB, member RAS oncogene family-like 6 0.0199134
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0198383
ATP11B ATPase, class VI, type 11B 0.0198365
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.0198326
TTF1 transcription termination factor, RNA polymerase I 0.0198284
INO80D INO80 complex subunit D 0.0198132
TSC22D1 TSC22 domain family, member 1 0.0197587
SRRM2 serine/arginine repetitive matrix 2 0.0197037
RAB8B RAB8B, member RAS oncogene family 0.0196769
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0196451
WDR44 WD repeat domain 44 0.019643
SYNJ1 synaptojanin 1 0.0196211
BRWD1 bromodomain and WD repeat domain containing 1 0.0196135
LIN9 lin-9 DREAM MuvB core complex component 0.0195886
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 0.0195362
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.0195328
LRRC8B leucine rich repeat containing 8 family, member B 0.0195214
PCED1B PC-esterase domain containing 1B 0.0195204
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0194923
NUB1 negative regulator of ubiquitin-like proteins 1 0.0194225
H2AC6 H2A clustered histone 6 0.0194026
USP47 ubiquitin specific peptidase 47 0.0193611
RAP1A RAP1A, member of RAS oncogene family 0.019289
WDR70 WD repeat domain 70 0.0192559
NVL nuclear VCP-like 0.0192031
MYO18B myosin XVIIIB 0.0191311
UBAC2 UBA domain containing 2 0.0190683
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.019042
CREB1 cAMP responsive element binding protein 1 0.019038
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.0189707
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0189703
ARG2 arginase 2 0.0189612
POTEF POTE ankyrin domain family, member F 0.0189249
SHTN1 shootin 1 0.0189089
ANAPC16 anaphase promoting complex subunit 16 0.0188856
DSCAM Down syndrome cell adhesion molecule 0.0188025
KRIT1 KRIT1, ankyrin repeat containing 0.0187966
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.0187481
ERMP1 endoplasmic reticulum metallopeptidase 1 0.018722
SMC6 structural maintenance of chromosomes 6 0.018657
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0186423
LRRC61 leucine rich repeat containing 61 0.018623
SKI SKI proto-oncogene 0.0186226
FBXO42 F-box protein 42 0.0185972
TMEM230 transmembrane protein 230 0.0185945
CLIP1 CAP-GLY domain containing linker protein 1 0.0185884
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0185787
INTS7 integrator complex subunit 7 0.0185629
STX6 syntaxin 6 0.0185127
FNDC3A fibronectin type III domain containing 3A 0.0184707
ZNF407 zinc finger protein 407 0.0184394
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0184276
BLVRB biliverdin reductase B 0.0184252
TACC1 transforming, acidic coiled-coil containing protein 1 0.0184193
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.0183905
ADNP activity-dependent neuroprotector homeobox 0.0183899
NCOA2 nuclear receptor coactivator 2 0.0183583
NBAS neuroblastoma amplified sequence 0.0183355
MGST3 microsomal glutathione S-transferase 3 0.0183247
SNX29 sorting nexin 29 0.0183133
N4BP2 NEDD4 binding protein 2 0.0183071
TTF2 transcription termination factor, RNA polymerase II 0.0182983
YEATS2 YEATS domain containing 2 0.0182675
BAIAP2L1 BAI1-associated protein 2-like 1 0.0182646
NSD2 nuclear receptor binding SET domain protein 2 0.0182502
HMGN1 high mobility group nucleosome binding domain 1 0.0182428
CLOCK clock circadian regulator 0.0182386
MAPK9 mitogen-activated protein kinase 9 0.0182267
RSRC1 arginine/serine-rich coiled-coil 1 0.018196
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.0181615
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 0.0181429
IGSF1 immunoglobulin superfamily, member 1 0.0181395
ANKMY2 ankyrin repeat and MYND domain containing 2 0.0181311
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.018092
TP53BP2 tumor protein p53 binding protein 2 0.0180772
GATAD2B GATA zinc finger domain containing 2B 0.0180714
RAB10 RAB10, member RAS oncogene family 0.0180147
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.01795
ZFPM1 zinc finger protein, FOG family member 1 0.0179482
PRPF3 pre-mRNA processing factor 3 0.0179157
LATS1 large tumor suppressor kinase 1 0.0178521
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.0178338
TMEM131 transmembrane protein 131 0.0178104
CLASP1 cytoplasmic linker associated protein 1 0.017775
RPL32 ribosomal protein L32 0.0177395
TCP1 t-complex 1 0.0177345
NIPSNAP2 nipsnap homolog 2 0.0177166
NCAPG non-SMC condensin I complex, subunit G 0.0177149
NSUN4 NOP2/Sun domain family, member 4 0.0177031
CCNT2 cyclin T2 0.0176918
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 0.0176546
ZMYM2 zinc finger, MYM-type 2 0.0176401
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.0176326
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0176289
DMWD dystrophia myotonica, WD repeat containing 0.0176155
TALDO1 transaldolase 1 0.0175923
LSR lipolysis stimulated lipoprotein receptor 0.0175898
LNPK lunapark, ER junction formation factor 0.0175828
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.0175782
TTK TTK protein kinase 0.0175777
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.0175697
COQ4 coenzyme Q4 0.0175521
SOS2 son of sevenless homolog 2 (Drosophila) 0.0175309
TMEM164 transmembrane protein 164 0.0175063
SLC44A5 solute carrier family 44, member 5 0.0174986
FAM222B family with sequence similarity 222, member B 0.0174973
USP3 ubiquitin specific peptidase 3 0.017477
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.0174615
TRIB3 tribbles pseudokinase 3 0.017444
SYNRG synergin, gamma 0.0174434
C9ORF78 chromosome 9 open reading frame 78 0.0174006
DNASE2 deoxyribonuclease II, lysosomal 0.0173864
BTBD2 BTB (POZ) domain containing 2 0.0173517
AQR aquarius intron-binding spliceosomal factor 0.0172906
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.017289
CNOT7 CCR4-NOT transcription complex, subunit 7 0.0172882
UNK unkempt family zinc finger 0.0172743
SERTAD2 SERTA domain containing 2 0.017265
PTPRR protein tyrosine phosphatase, receptor type, R 0.0172188
EHBP1 EH domain binding protein 1 0.017218
VWDE von Willebrand factor D and EGF domains 0.0172088
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.0172071
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0171678
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0171452
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.0171172
TMCO1 transmembrane and coiled-coil domains 1 0.0171094
FKBP14 FK506 binding protein 14, 22 kDa 0.0171072
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0170569
MAVS mitochondrial antiviral signaling protein 0.0170503
MED28 mediator complex subunit 28 0.0170404
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.0170369
DOP1A DOP1 leucine zipper like protein A 0.0170253
MORC3 MORC family CW-type zinc finger 3 0.0170014
CHD6 chromodomain helicase DNA binding protein 6 0.0169952
NCALD neurocalcin delta 0.0169498
KIF18A kinesin family member 18A 0.0169304
CYTH1 cytohesin 1 0.0168961
NFE2L2 nuclear factor, erythroid 2-like 2 0.0168634
NUP58 nucleoporin 58 0.0168506
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0168445
ANKRD26 ankyrin repeat domain 26 0.0168249
SDCCAG8 serologically defined colon cancer antigen 8 0.0167447
FYCO1 FYVE and coiled-coil domain containing 1 0.0167233
TMOD1 tropomodulin 1 0.0167232
PCYOX1 prenylcysteine oxidase 1 0.0167216
PGAP2 post-GPI attachment to proteins 2 0.0167139
PRRC2B proline-rich coiled-coil 2B 0.0167001
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.0166923
NMT2 N-myristoyltransferase 2 0.0166729
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0166387
SEC62 SEC62 homolog (S. cerevisiae) 0.0166364
DMTF1 cyclin D binding myb-like transcription factor 1 0.0166279
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.0164888
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.0164654
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0164514
DIPK1A divergent protein kinase domain 1A 0.0164016
IVNS1ABP influenza virus NS1A binding protein 0.0163845
CD109 CD109 molecule 0.0163782
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0163581
TMEM219 transmembrane protein 219 0.0163559
MED23 mediator complex subunit 23 0.016307
UHMK1 U2AF homology motif (UHM) kinase 1 0.0162992
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0162535
CCDC91 coiled-coil domain containing 91 0.0162426
CD47 CD47 molecule 0.0162269
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.0162042
PRR11 proline rich 11 0.016201
HDAC1 histone deacetylase 1 0.0161895
ZGRF1 zinc finger, GRF-type containing 1 0.0161041
TMEM50B transmembrane protein 50B 0.0160961
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0160085
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.0159983
DBF4 DBF4 zinc finger 0.0159639
PANK3 pantothenate kinase 3 0.0159015
SIRT7 sirtuin 7 0.0158596
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0158216
MED15 mediator complex subunit 15 0.0158199
DDHD1 DDHD domain containing 1 0.0158147
PPP1R12C protein phosphatase 1, regulatory subunit 12C 0.0158094
CHEK1 checkpoint kinase 1 0.0157996
WIPI2 WD repeat domain, phosphoinositide interacting 2 0.0157932
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.0157824
CLCN7 chloride channel, voltage-sensitive 7 0.0157603
HDLBP high density lipoprotein binding protein 0.0157546
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.0157545
BIRC6 baculoviral IAP repeat containing 6 0.0157451
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0157065
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0157034
SPPL3 signal peptide peptidase like 3 0.0156954
CEP104 centrosomal protein 104kDa 0.0156885
MICALL2 MICAL-like 2 0.015684
TLK2 tousled-like kinase 2 0.015648
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0156379
NAMPT nicotinamide phosphoribosyltransferase 0.015617
HBA2 hemoglobin, alpha 2 0.0156036
METTL5 methyltransferase like 5 0.0155921
CCDC186 coiled-coil domain containing 186 0.0155702
NDC1 NDC1 transmembrane nucleoporin 0.0155106
GMEB1 glucocorticoid modulatory element binding protein 1 0.0155054
COP1 COP1 E3 ubiquitin ligase 0.015496
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0154523
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0154465
ZNF37A zinc finger protein 37A 0.0154383
ANKRD36C ankyrin repeat domain 36C 0.0153958
CENPC centromere protein C 0.0153718
YY1AP1 YY1 associated protein 1 0.0153515
FRMD8 FERM domain containing 8 0.0152574
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.0152569
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.0152555
MFN2 mitofusin 2 0.0152448
KIF21A kinesin family member 21A 0.0152359
CSNK1G3 casein kinase 1, gamma 3 0.0152301
UBE2H ubiquitin-conjugating enzyme E2H 0.0152012
SS18 synovial sarcoma translocation, chromosome 18 0.0151501
ARL8B ADP-ribosylation factor-like 8B 0.0151414
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.0151382
TRIP12 thyroid hormone receptor interactor 12 0.015129
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0151278
PRKCI protein kinase C, iota 0.015121
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.0150441
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.0150368
TOM1L2 target of myb1-like 2 (chicken) 0.0150285
MPV17 MpV17 mitochondrial inner membrane protein 0.015019
POU6F2 POU class 6 homeobox 2 0.0149942
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 0.014991
SECISBP2 SECIS binding protein 2 0.0149883
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0149695
PICALM phosphatidylinositol binding clathrin assembly protein 0.0149649
ZNF207 zinc finger protein 207 0.014945
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.0149333
SESN3 sestrin 3 0.0148854
GNAS GNAS complex locus 0.014885
DENND1B DENN/MADD domain containing 1B 0.0148774
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.0148734
SFXN5 sideroflexin 5 0.014858
TULP4 tubby like protein 4 0.0148562
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.0148403
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 0.0147846
ZFAT zinc finger and AT hook domain containing 0.0147672
WDR20 WD repeat domain 20 0.0147503
INPPL1 inositol polyphosphate phosphatase-like 1 0.0147456
DCAF6 DDB1 and CUL4 associated factor 6 0.0146944
PRPF38B pre-mRNA processing factor 38B 0.014683
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.0146749
DENND4C DENN/MADD domain containing 4C 0.0146725

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.104832
RABGAP1L RAB GTPase activating protein 1-like -0.0769254
ZEB2 zinc finger E-box binding homeobox 2 -0.0677352
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.067208
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0663667
PKN2 protein kinase N2 -0.0644684
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0630899
ZMYND8 zinc finger, MYND-type containing 8 -0.0607928
SLC38A1 solute carrier family 38, member 1 -0.0594115
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0574196
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0531519
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0529285
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0523804
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -0.0516407
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0515879
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0515025
FLNA filamin A, alpha -0.0488704
AIG1 androgen-induced 1 -0.0484476
LDLR low density lipoprotein receptor -0.0473626
DIAPH1 diaphanous-related formin 1 -0.0471077
ANTXR2 anthrax toxin receptor 2 -0.0466088
RTN3 reticulon 3 -0.0458381
MUSK muscle, skeletal, receptor tyrosine kinase -0.0450026
CNKSR3 CNKSR family member 3 -0.0448902
ACTN4 actinin, alpha 4 -0.0439928
BRCA1 breast cancer 1, early onset -0.0437195
NRDC nardilysin convertase -0.0432188
RHAG Rh-associated glycoprotein -0.0429889
CHD4 chromodomain helicase DNA binding protein 4 -0.042007
GPC5 glypican 5 -0.0419328
SETX senataxin -0.0411249
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.04067
PDS5A PDS5 cohesin associated factor A -0.0402589
MAP4 microtubule-associated protein 4 -0.0397722
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0397388
C6ORF89 chromosome 6 open reading frame 89 -0.0396441
CALR calreticulin -0.0388741
ATXN7L1 ataxin 7-like 1 -0.0387369
EVL Enah/Vasp-like -0.0387002
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.0381936
ADAM17 ADAM metallopeptidase domain 17 -0.0381648
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0380784
WAC WW domain containing adaptor with coiled-coil -0.0379589
WDR26 WD repeat domain 26 -0.0379317
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0378272
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -0.0370887
TMOD3 tropomodulin 3 (ubiquitous) -0.0369908
MED13L mediator complex subunit 13-like -0.036684
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0366458
ACBD6 acyl-CoA binding domain containing 6 -0.0363957
CLIC4 chloride intracellular channel 4 -0.0361913
TPM3 tropomyosin 3 -0.0360841
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0360302
PRKCSH protein kinase C substrate 80K-H -0.0351931
JARID2 jumonji, AT rich interactive domain 2 -0.0351452
CORO2A coronin, actin binding protein, 2A -0.0351337
MECP2 methyl CpG binding protein 2 -0.0351065
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0346788
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0346224
TRAPPC10 trafficking protein particle complex 10 -0.0342582
GRAP2 GRB2-related adaptor protein 2 -0.0341891
CLASP2 cytoplasmic linker associated protein 2 -0.034017
PHF14 PHD finger protein 14 -0.0339972
HOMER1 homer scaffolding protein 1 -0.0335453
GCLM glutamate-cysteine ligase, modifier subunit -0.0332279
RPS5 ribosomal protein S5 -0.0330178
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0325472
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0322028
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0320095
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0319969
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0319553
ARHGAP11B Rho GTPase activating protein 11B -0.0317308
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.0317132
ENOSF1 enolase superfamily member 1 -0.0316152
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0315181
RPS2 ribosomal protein S2 -0.0314573
NUP205 nucleoporin 205kDa -0.0313772
COASY CoA synthase -0.0312891
TMEM245 transmembrane protein 245 -0.031186
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0311741
UBAP2 ubiquitin associated protein 2 -0.0310635
SETD5 SET domain containing 5 -0.0307353
NUP214 nucleoporin 214kDa -0.030696
RPS3 ribosomal protein S3 -0.0305761
TCF25 transcription factor 25 (basic helix-loop-helix) -0.0305229
TNPO3 transportin 3 -0.0303007
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0300363
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0299979
ABHD2 abhydrolase domain containing 2 -0.0299815
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0299311
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0298714
RC3H1 ring finger and CCCH-type domains 1 -0.0297854
WWC2 WW and C2 domain containing 2 -0.0297237
PDCD11 programmed cell death 11 -0.0296666
CEP192 centrosomal protein 192kDa -0.029634
OSBP oxysterol binding protein -0.0293282
TENM1 teneurin transmembrane protein 1 -0.0292333
CHML choroideremia-like (Rab escort protein 2) -0.0291931
SMC1A structural maintenance of chromosomes 1A -0.0291746
RAB7A RAB7A, member RAS oncogene family -0.0291112
PTPRA protein tyrosine phosphatase, receptor type, A -0.0289367
ECPAS Ecm29 proteasome adaptor and scaffold -0.0287325
STAT5A signal transducer and activator of transcription 5A -0.028703
RPL28 ribosomal protein L28 -0.028666
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0283344
MVD mevalonate (diphospho) decarboxylase -0.028296
ATG7 autophagy related 7 -0.0282629
SLC39A11 solute carrier family 39, member 11 -0.0282387
SMC3 structural maintenance of chromosomes 3 -0.0281993
RELN reelin -0.0281753
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.0281525
RANBP10 RAN binding protein 10 -0.0280596
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0279805
RPL30 ribosomal protein L30 -0.0279199
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0278626
RPL29 ribosomal protein L29 -0.0276844
NSD1 nuclear receptor binding SET domain protein 1 -0.0276617
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0273539
MMS22L MMS22-like, DNA repair protein -0.0272106
LMTK2 lemur tyrosine kinase 2 -0.0268593
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0266337
NUP153 nucleoporin 153kDa -0.0266274
CCDC47 coiled-coil domain containing 47 -0.0265773
AGO1 argonaute RISC catalytic component 1 -0.0264243
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0264099
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.026297
SRSF4 serine/arginine-rich splicing factor 4 -0.0262849
EEF2 eukaryotic translation elongation factor 2 -0.0261823
CAPRIN1 cell cycle associated protein 1 -0.0258107
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0257159
CFAP161 cilia and flagella associated protein 161 -0.0256773
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -0.0256552
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0255873
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.0255608
NFYC nuclear transcription factor Y, gamma -0.0254637
HSF1 heat shock transcription factor 1 -0.0254266
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.0252596
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -0.0252132
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0251888
FAF1 Fas (TNFRSF6) associated factor 1 -0.0251766
RC3H2 ring finger and CCCH-type domains 2 -0.0250719
MLXIP MLX interacting protein -0.0248312
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0246258
CDK6 cyclin-dependent kinase 6 -0.0244362
FASN fatty acid synthase -0.0244334
NAP1L1 nucleosome assembly protein 1-like 1 -0.024343
REEP3 receptor accessory protein 3 -0.0243331
PCDH9 protocadherin 9 -0.0243072
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.024214
KRT8 keratin 8, type II -0.0240991
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0240208
MDN1 MDN1, midasin homolog (yeast) -0.023876
MCM7 minichromosome maintenance complex component 7 -0.0238478
COMT catechol-O-methyltransferase -0.0238285
HP1BP3 heterochromatin protein 1, binding protein 3 -0.023808
EPS15 epidermal growth factor receptor pathway substrate 15 -0.0236824
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0236736
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0236472
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein -0.0236181
ODR4 odr-4 GPCR localization factor homolog -0.0236084
GGNBP2 gametogenetin binding protein 2 -0.0235684
DGCR2 DiGeorge syndrome critical region gene 2 -0.0235598
FBXO28 F-box protein 28 -0.0235592
TPR translocated promoter region, nuclear basket protein -0.0234714
CCAR1 cell division cycle and apoptosis regulator 1 -0.0234495
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0234294
FUCA2 fucosidase, alpha-L- 2, plasma -0.0233988
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0233788
CTBP2 C-terminal binding protein 2 -0.0233608
GALK2 galactokinase 2 -0.0232968
SPIRE1 spire-type actin nucleation factor 1 -0.0232123
LSG1 large 60S subunit nuclear export GTPase 1 -0.0231215
ANKLE2 ankyrin repeat and LEM domain containing 2 -0.0229538
RBL1 retinoblastoma-like 1 -0.0229274
XPO7 exportin 7 -0.0229029
MKI67 marker of proliferation Ki-67 -0.0228999
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -0.0228268
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0227862
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0227618
RPL27A ribosomal protein L27a -0.0226846
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.0226444
COMMD10 COMM domain containing 10 -0.0226283
PPHLN1 periphilin 1 -0.0225878
TERF2 telomeric repeat binding factor 2 -0.0225699
HBG2 hemoglobin, gamma G -0.0225313
CRTC3 CREB regulated transcription coactivator 3 -0.0224974
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.0224409
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0223824
FOXJ3 forkhead box J3 -0.0223303
CPPED1 calcineurin-like phosphoesterase domain containing 1 -0.0222583
IMMT inner membrane protein, mitochondrial -0.0222344
RPS23 ribosomal protein S23 -0.0222322
CLIC1 chloride intracellular channel 1 -0.0221249
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0221131
PCM1 pericentriolar material 1 -0.022104
CALN1 calneuron 1 -0.0219928
RPS16 ribosomal protein S16 -0.0219845
CASP8AP2 caspase 8 associated protein 2 -0.0219546
REDIC1 regulator of DNA class I crossover intermediates 1 -0.0218252
HSPA8 heat shock 70kDa protein 8 -0.0217663
ERI3 ERI1 exoribonuclease family member 3 -0.021744
RPL38 ribosomal protein L38 -0.0217326
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0217242
ESYT1 extended synaptotagmin-like protein 1 -0.021687
PTBP2 polypyrimidine tract binding protein 2 -0.0216665
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0215189
PA2G4 proliferation-associated 2G4, 38kDa -0.0215003
XKR3 XK, Kell blood group complex subunit-related family, member 3 -0.0214727
LEPROT leptin receptor overlapping transcript -0.0214713
USP32 ubiquitin specific peptidase 32 -0.0214452
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0213741
TUFM Tu translation elongation factor, mitochondrial -0.0213392
MAST2 microtubule associated serine/threonine kinase 2 -0.0213246
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0213103
MLEC malectin -0.0212998
CDC27 cell division cycle 27 -0.0212888
MTMR14 myotubularin related protein 14 -0.0212834
RAD23B RAD23 homolog B (S. cerevisiae) -0.021283
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0212412
TFCP2 transcription factor CP2 -0.0212158
TET3 tet methylcytosine dioxygenase 3 -0.0212153
HBS1L HBS1-like translational GTPase -0.021195
CCDC57 coiled-coil domain containing 57 -0.0211914
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.021176
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0211744
ELOVL6 ELOVL fatty acid elongase 6 -0.0211721
VARS1 valyl-tRNA synthetase 1 -0.0211635
RPL12 ribosomal protein L12 -0.0211388
WARS1 tryptophanyl-tRNA synthetase 1 -0.0211385
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.0211141
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0210544
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0210199
PSPC1 paraspeckle component 1 -0.0209602
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0209285
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.020883
SCAND3 SCAN domain containing 3 -0.0207507
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.0207484
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0207266
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0206747
CAPN2 calpain 2, (m/II) large subunit -0.0206559
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0206518
RALGDS ral guanine nucleotide dissociation stimulator -0.0206246
ECI1 enoyl-CoA delta isomerase 1 -0.0206116
ADGRE2 adhesion G protein-coupled receptor E2 -0.0206
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0205222
PCNX4 pecanex 4 -0.0205093
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.0205085
EMP3 epithelial membrane protein 3 -0.0204822
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.020424
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0203909
UBA2 ubiquitin-like modifier activating enzyme 2 -0.020387
EXOC4 exocyst complex component 4 -0.0203586
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0203294
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -0.0203089
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.0202377
OGA O-GlcNAcase -0.0202209
TAPBP TAP binding protein (tapasin) -0.020198
BST2 bone marrow stromal cell antigen 2 -0.0201572
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.0201458
PHGDH phosphoglycerate dehydrogenase -0.0201237
PROC protein C (inactivator of coagulation factors Va and VIIIa) -0.0200874
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.020076
HMGB1 high mobility group box 1 -0.0200299
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0200199
TRAK1 trafficking protein, kinesin binding 1 -0.0199993
BSG basigin (Ok blood group) -0.0199859
ECSIT ECSIT signalling integrator -0.019952
TOP2B topoisomerase (DNA) II beta 180kDa -0.0199059
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0198898
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0198666
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0198384
FAF2 Fas associated factor family member 2 -0.0197523
SETD2 SET domain containing 2 -0.0197282
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.019678
RAB31 RAB31, member RAS oncogene family -0.0196509
KMT5A lysine methyltransferase 5A -0.0196486
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.0196483
TMEM209 transmembrane protein 209 -0.0196343
GK5 glycerol kinase 5 (putative) -0.0196034
GSTP1 glutathione S-transferase pi 1 -0.0196024
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0195716
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.0193716
RNF115 ring finger protein 115 -0.0193119
GPBP1 GC-rich promoter binding protein 1 -0.0193073
YLPM1 YLP motif containing 1 -0.0192877
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.0192728
SACK1H scaffolding CK1 anchoring protein H -0.0192711
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0192194
CSMD1 CUB and Sushi multiple domains 1 -0.0191455
GOLGA4 golgin A4 -0.0190832
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -0.0190607
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -0.0190515
SLMAP sarcolemma associated protein -0.0190476
FLT1 fms-related tyrosine kinase 1 -0.0190379
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0190158
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.019012
LYRM7 LYR motif containing 7 -0.0189866
PRKCA protein kinase C, alpha -0.0189716
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains -0.0189628
PLCL1 phospholipase C-like 1 -0.0189533
CENPP centromere protein P -0.0189466
NR2C1 nuclear receptor subfamily 2, group C, member 1 -0.0189177
ATP5MC2 ATP synthase membrane subunit c locus 2 -0.0189074
RPL34 ribosomal protein L34 -0.0188805
MFSD11 major facilitator superfamily domain containing 11 -0.0188208
PPARD peroxisome proliferator-activated receptor delta -0.0188092
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0187852
TRIM44 tripartite motif containing 44 -0.0186826
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0186704
THRB thyroid hormone receptor, beta -0.0186356
FOXK2 forkhead box K2 -0.0185619
MEIS2 Meis homeobox 2 -0.0185518
FAM171A1 family with sequence similarity 171, member A1 -0.0185104
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.0185084
RPL39 ribosomal protein L39 -0.018435
CCNF cyclin F -0.0183811
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.0183739
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -0.0183598
FBH1 F-box DNA helicase 1 -0.0183176
UBTF upstream binding transcription factor, RNA polymerase I -0.0183167
GOLGA3 golgin A3 -0.0183132
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -0.0182932
BRI3BP BRI3 binding protein -0.0182898
USP42 ubiquitin specific peptidase 42 -0.018234
TPI1 triosephosphate isomerase 1 -0.018124
ATL2 atlastin GTPase 2 -0.0181174
CHLSN cholesin -0.0181123
ECD ecdysoneless homolog (Drosophila) -0.0180945
WDR45 WD repeat domain 45 -0.0180857
NUMA1 nuclear mitotic apparatus protein 1 -0.0180791
FAM168B family with sequence similarity 168, member B -0.0180731
GAB2 GRB2-associated binding protein 2 -0.0180726
RPL14 ribosomal protein L14 -0.0180725
EIF4E eukaryotic translation initiation factor 4E -0.0180384
DOT1L DOT1-like histone H3K79 methyltransferase -0.0179944
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -0.0179553
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -0.0179533
RBM25 RNA binding motif protein 25 -0.017946
EVI5 ecotropic viral integration site 5 -0.0179381
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -0.0179331
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -0.0179191
NFE2 nuclear factor, erythroid 2 -0.0178985
EMSY EMSY transcriptional repressor, BRCA2 interacting -0.0178936
SLC35D4 solute carrier family 35 member D4 -0.0178337
NMU neuromedin U -0.0178047
RBM39 RNA binding motif protein 39 -0.0177963
TPST2 tyrosylprotein sulfotransferase 2 -0.0177619
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.0177433
CYB561 cytochrome b561 -0.0176912
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -0.0176864
TXN2 thioredoxin 2 -0.0176864
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -0.0176161
HSPB1 heat shock 27kDa protein 1 -0.0176137
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0174659
ABHD5 abhydrolase domain containing 5 -0.0174515
CEP83 centrosomal protein 83kDa -0.0174028
SCFD1 sec1 family domain containing 1 -0.0173819
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.0173729
TRIM27 tripartite motif containing 27 -0.0173505
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.0173423
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.0173228
SERBP1 SERPINE1 mRNA binding protein 1 -0.0173131
TM9SF4 transmembrane 9 superfamily protein member 4 -0.0172788
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0172771
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0172566
COPE coatomer protein complex, subunit epsilon -0.0172442
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0172326
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -0.0172073
ZNF212 zinc finger protein 212 -0.0171373
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0171176
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -0.0170872
SPC24 SPC24, NDC80 kinetochore complex component -0.0170559
CTNNBIP1 catenin, beta interacting protein 1 -0.01705
SIN3A SIN3 transcription regulator family member A -0.0170332
RPS19 ribosomal protein S19 -0.0170204
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -0.0170137
MYO18A myosin XVIIIA -0.0169947
COTL1 coactosin-like F-actin binding protein 1 -0.0169699
FBXO38 F-box protein 38 -0.0169589
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0169237
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -0.0169187
GOSR1 golgi SNAP receptor complex member 1 -0.0169061
PRMT3 protein arginine methyltransferase 3 -0.0168995
INTS4 integrator complex subunit 4 -0.0168751
NUP133 nucleoporin 133kDa -0.0168418
ESRRB estrogen-related receptor beta -0.0168114
CARS1 cysteinyl-tRNA synthetase 1 -0.0167631
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -0.016757
UGDH UDP-glucose 6-dehydrogenase -0.0167548
TMEM50A transmembrane protein 50A -0.0167273
NRF1 nuclear respiratory factor 1 -0.016717
ZSWIM5 zinc finger, SWIM-type containing 5 -0.0166967
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0166895
RFWD3 ring finger and WD repeat domain 3 -0.0166662
CCNI cyclin I -0.0166596
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -0.0166507
XXYLT1 xyloside xylosyltransferase 1 -0.0166448
S100PBP S100P binding protein -0.0166413
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0166392
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.016623
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -0.0165835
CEP152 centrosomal protein 152kDa -0.0165628
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -0.0165556
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -0.0165418
CFAP251 cilia and flagella associated protein 251 -0.0165022
TMEM59 transmembrane protein 59 -0.0164872
IPO7 importin 7 -0.0164821
DCAF1 DDB1 and CUL4 associated factor 1 -0.016477
SOAT2 sterol O-acyltransferase 2 -0.0164689
TBP TATA box binding protein -0.0164617
CASS4 Cas scaffolding protein family member 4 -0.0164363
VIRMA vir like m6A methyltransferase associated -0.0164297
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0164122
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0164052
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.016336
DUT deoxyuridine triphosphatase -0.0163257
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) -0.0163058
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0162882
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -0.0162399
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 -0.0162109
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -0.0161875
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0161865
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.0161525
TNPO2 transportin 2 -0.0161295
KAT6A K(lysine) acetyltransferase 6A -0.0161263
DTNBP1 dystrobrevin binding protein 1 -0.016124
PRAME preferentially expressed antigen in melanoma -0.0160944
MACO1 macoilin 1 -0.0160932
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa -0.0160872
THEM4 thioesterase superfamily member 4 -0.016075
INO80 INO80 complex subunit -0.0160565
CRTC1 CREB regulated transcription coactivator 1 -0.0160506
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0160466
RAB27A RAB27A, member RAS oncogene family -0.0160352
SFPQ splicing factor proline/glutamine-rich -0.0160094
HOMER2 homer scaffolding protein 2 -0.0160067
KIDINS220 kinase D-interacting substrate, 220kDa -0.0160057
MED12 mediator complex subunit 12 -0.0160026
WDR33 WD repeat domain 33 -0.0160015
KMT5B lysine methyltransferase 5B -0.0159988
RBM14-RBM4 RBM14-RBM4 readthrough -0.0159751
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0159559
GMDS GDP-mannose 4,6-dehydratase -0.0159343
RNF4 ring finger protein 4 -0.0159256
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0158891
RBBP4 retinoblastoma binding protein 4 -0.0158768
TXNRD2 thioredoxin reductase 2 -0.0158496
KHSRP KH-type splicing regulatory protein -0.0158419
FANCA Fanconi anemia, complementation group A -0.0158291
PCSK7 proprotein convertase subtilisin/kexin type 7 -0.0157863
SZRD1 SUZ RNA binding domain containing 1 -0.0157828
CDYL chromodomain protein, Y-like -0.0157813
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C -0.0157781
SEH1L SEH1-like (S. cerevisiae) -0.0156808
GCC2 GRIP and coiled-coil domain containing 2 -0.0155753
CFAP20DC CFAP20 domain containing -0.0155289
UBL4A ubiquitin-like 4A -0.0155275
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0155185
SLF2 SMC5-SMC6 complex localization factor 2 -0.0155025
HMOX2 heme oxygenase 2 -0.0154967
CDK12 cyclin-dependent kinase 12 -0.0154924
SUGP1 SURP and G patch domain containing 1 -0.0154759
POM121C POM121 transmembrane nucleoporin C -0.0154635
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.015425
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.0154189
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0154173
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.0154132
SF3A3 splicing factor 3a, subunit 3, 60kDa -0.0153942
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -0.0153753
FBXL5 F-box and leucine-rich repeat protein 5 -0.0153583
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.0153282
ESRRA estrogen-related receptor alpha -0.0153262
MCM6 minichromosome maintenance complex component 6 -0.015316
SPOPL speckle-type POZ protein-like -0.0152991
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0152714
DCAF10 DDB1 and CUL4 associated factor 10 -0.0152709
PPP1R8 protein phosphatase 1, regulatory subunit 8 -0.0152643
CUL2 cullin 2 -0.015236
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.0152334
RPS12 ribosomal protein S12 -0.0152209
CD59 CD59 molecule, complement regulatory protein -0.015179
STIL SCL/TAL1 interrupting locus -0.0151366
CRY1 cryptochrome circadian clock 1 -0.0151045
MYO16 myosin XVI -0.0151029
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.015096
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -0.0150606
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0150519
NR2F6 nuclear receptor subfamily 2, group F, member 6 -0.0150502
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.015041
NOL4L nucleolar protein 4-like -0.0150394
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -0.0150232
HIP1 huntingtin interacting protein 1 -0.0150081
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0150047
ERO1B endoplasmic reticulum oxidoreductase 1 beta -0.0149984
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -0.0149913
KDM3B lysine (K)-specific demethylase 3B -0.0149853
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0149693
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0149648
SHLD2 shieldin complex subunit 2 -0.0149474
COG7 component of oligomeric golgi complex 7 -0.0149439