KARPAS-422 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human B cell lymphoma cell line; established from the pleural effusion of a 73-year-old woman with B cell non-Hodgkin lymphoma (intraabdominal, diffuse large cell lymphoma, refractory, terminal) in 1987. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004981)
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Genes

723 genes with high or low expression in KARPAS-422 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
MAPRE2 microtubule-associated protein, RP/EB family, member 2 3.55453
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 3.46866
RGS19 regulator of G-protein signaling 19 3.42553
SLC6A16 solute carrier family 6, member 16 3.3026
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 3.27593
KIAA0226 KIAA0226 3.25339
EHD3 EH-domain containing 3 3.23401
TRAF3 TNF receptor-associated factor 3 3.22972
ESR2 estrogen receptor 2 (ER beta) 3.2196
CRLF3 cytokine receptor-like factor 3 3.16319
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 3.13062
YY1 YY1 transcription factor 3.06263
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 3.04125
CAMP cathelicidin antimicrobial peptide 3.02291
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.98332
PDGFD platelet derived growth factor D 2.95494
MOB1A MOB kinase activator 1A 2.94968
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.94381
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 2.90564
RFC3 replication factor C (activator 1) 3, 38kDa 2.83311
STK17B serine/threonine kinase 17b 2.82618
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.78494
MYRIP myosin VIIA and Rab interacting protein 2.78427
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 2.78067
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 2.77483
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 2.69374
ANKRD26 ankyrin repeat domain 26 2.68559
TMEM38B transmembrane protein 38B 2.67322
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.65413
MYO9A myosin IXA 2.65004
RNF19B ring finger protein 19B 2.638
BPTF bromodomain PHD finger transcription factor 2.61998
EGLN1 egl-9 family hypoxia-inducible factor 1 2.61904
ANKRD49 ankyrin repeat domain 49 2.61899
ALOX5 arachidonate 5-lipoxygenase 2.61619
NSD1 nuclear receptor binding SET domain protein 1 2.61565
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 2.6107
BCAS4 breast carcinoma amplified sequence 4 2.597
HECA headcase homolog (Drosophila) 2.59407
FCRL2 Fc receptor-like 2 2.55473
EED embryonic ectoderm development 2.52922
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.50844
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 2.50648
ARHGAP25 Rho GTPase activating protein 25 2.47102
NDC1 NDC1 transmembrane nucleoporin 2.44287
BCL6 B-cell CLL/lymphoma 6 2.4399
MEGF9 multiple EGF-like-domains 9 2.43513
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.42677
CCDC109B coiled-coil domain containing 109B 2.41459
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.40932
AFF2 AF4/FMR2 family, member 2 2.39934
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 2.39893
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.39128
VPREB3 pre-B lymphocyte 3 2.38
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.3754
RPIA ribose 5-phosphate isomerase A 2.35686
ATXN7 ataxin 7 2.35073
GCH1 GTP cyclohydrolase 1 2.34557
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2.3417
CD1C CD1c molecule 2.33535
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 2.32948
KDM3A lysine (K)-specific demethylase 3A 2.32196
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 2.31802
RBM38 RNA binding motif protein 38 2.31755
ZHX2 zinc fingers and homeoboxes 2 2.29629
PQLC1 PQ loop repeat containing 1 2.29487
FBXO41 F-box protein 41 2.29244
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 2.28727
CDV3 CDV3 homolog (mouse) 2.28507
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 2.27286
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 2.26988
CREBZF CREB/ATF bZIP transcription factor 2.26783
MAPK10 mitogen-activated protein kinase 10 2.26601
ZNF701 zinc finger protein 701 2.24405
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.241
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.23332
CD37 CD37 molecule 2.211
ZNF589 zinc finger protein 589 2.20273
STAT5B signal transducer and activator of transcription 5B 2.18718
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.18459
METAP2 methionyl aminopeptidase 2 2.18094
RAD17 RAD17 homolog (S. pombe) 2.17864
KCNK12 potassium channel, two pore domain subfamily K, member 12 2.17747
YEATS2 YEATS domain containing 2 2.17307
CCDC28A coiled-coil domain containing 28A 2.15725
NEK9 NIMA-related kinase 9 2.14265
TDP1 tyrosyl-DNA phosphodiesterase 1 2.13969
PNOC prepronociceptin 2.13418
CEP57 centrosomal protein 57kDa 2.12603
CCDC69 coiled-coil domain containing 69 2.12332
MYBPH myosin binding protein H 2.117
ELL3 elongation factor RNA polymerase II-like 3 2.11391
SMAD2 SMAD family member 2 2.112
PPID peptidylprolyl isomerase D 2.10638
TCEA2 transcription elongation factor A (SII), 2 2.08848
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.08817
ZNHIT3 zinc finger, HIT-type containing 3 2.08713
PITX1 paired-like homeodomain 1 2.07795
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 2.07079
TMEM135 transmembrane protein 135 2.06493
FAM49B family with sequence similarity 49, member B 2.05107
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2.04627
ZNF318 zinc finger protein 318 2.04472
GMCL1 germ cell-less, spermatogenesis associated 1 2.04393
MEF2A myocyte enhancer factor 2A 2.04102
ZBTB25 zinc finger and BTB domain containing 25 2.04019
PEX3 peroxisomal biogenesis factor 3 2.03694
THOC7 THO complex 7 2.03374
USP25 ubiquitin specific peptidase 25 2.02661
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.02531
CD180 CD180 molecule 2.02524
CUL5 cullin 5 2.01255
PIAS2 protein inhibitor of activated STAT, 2 2.01166
RAD51B RAD51 paralog B 2.0066
CNTRL centriolin 1.98704
LTA lymphotoxin alpha 1.98596
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.98359
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.97894
TNNI1 troponin I type 1 (skeletal, slow) 1.97779
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 1.96952
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 1.96091
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1.9503
LY86 lymphocyte antigen 86 1.94934
ZMIZ1 zinc finger, MIZ-type containing 1 1.94425
VRK3 vaccinia related kinase 3 1.94332
TLK2 tousled-like kinase 2 1.93943
T T, brachyury homolog (mouse) 1.93562
SSTR2 somatostatin receptor 2 1.92949
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 1.92901
DSG1 desmoglein 1 1.92275
RGS13 regulator of G-protein signaling 13 1.92141
MAP2K6 mitogen-activated protein kinase kinase 6 1.91665
USP34 ubiquitin specific peptidase 34 1.91374
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 1.91317
SOS2 son of sevenless homolog 2 (Drosophila) 1.90902
NFU1 NFU1 iron-sulfur cluster scaffold 1.90786
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 1.90612
POU2AF1 POU class 2 associating factor 1 1.90497
SIK2 salt-inducible kinase 2 1.89208
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.89124
PTPRT protein tyrosine phosphatase, receptor type, T 1.88726
DVL2 dishevelled segment polarity protein 2 1.88722
GTF3A general transcription factor IIIA 1.87655
FAIM2 Fas apoptotic inhibitory molecule 2 1.87528
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 1.87342
BAG4 BCL2-associated athanogene 4 1.87103
HLA-DOB major histocompatibility complex, class II, DO beta 1.86412
CYB5R4 cytochrome b5 reductase 4 1.85989
CCDC90B coiled-coil domain containing 90B 1.85821
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 1.85757
BFSP2 beaded filament structural protein 2, phakinin 1.85686
TOPBP1 topoisomerase (DNA) II binding protein 1 1.85028
RSRC1 arginine/serine-rich coiled-coil 1 1.84806
CD79B CD79b molecule, immunoglobulin-associated beta 1.84775
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.84703
GPR18 G protein-coupled receptor 18 1.8455
NPAT nuclear protein, ataxia-telangiectasia locus 1.84239
TBCC tubulin folding cofactor C 1.83788
RPL39L ribosomal protein L39-like 1.83753
TOP1 topoisomerase (DNA) I 1.83008
SYPL1 synaptophysin-like 1 1.82606
ADORA2A adenosine A2a receptor 1.82588
YAF2 YY1 associated factor 2 1.81957
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.81667
ZNF236 zinc finger protein 236 1.81553
TLR1 toll-like receptor 1 1.81489
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.80923
ITPKB inositol-trisphosphate 3-kinase B 1.80633
TMEM57 transmembrane protein 57 1.80227
OSBPL3 oxysterol binding protein-like 3 1.80057
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 1.79736
PHF3 PHD finger protein 3 1.79676
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 1.79578
RTCA RNA 3'-terminal phosphate cyclase 1.79555
OPRL1 opiate receptor-like 1 1.7953
OXSR1 oxidative stress responsive 1 1.79421
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene 1.79158
SLC35F2 solute carrier family 35, member F2 1.79152
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 1.78668
ACAT1 acetyl-CoA acetyltransferase 1 1.78552
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 1.776
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 1.77583
ARID4A AT rich interactive domain 4A (RBP1-like) 1.77505
ZNF652 zinc finger protein 652 1.77419
CHUK conserved helix-loop-helix ubiquitous kinase 1.7723
ALDOC aldolase C, fructose-bisphosphate 1.77047
LRRC32 leucine rich repeat containing 32 1.76835
RHOT1 ras homolog family member T1 1.76511
MTUS2 microtubule associated tumor suppressor candidate 2 1.76422
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.76236
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.76146
METTL7A methyltransferase like 7A 1.7587
TBC1D22A TBC1 domain family, member 22A 1.7585
SIAH2 siah E3 ubiquitin protein ligase 2 1.75536
SNTA1 syntrophin, alpha 1 1.75404
PTPRC protein tyrosine phosphatase, receptor type, C 1.74229
RMDN1 regulator of microtubule dynamics 1 1.74043
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.73959
OSBPL10 oxysterol binding protein-like 10 1.73564
TMEM184C transmembrane protein 184C 1.73491
APC adenomatous polyposis coli 1.73013
MTX2 metaxin 2 1.71853
FDX1 ferredoxin 1 1.71412
DHRS4 dehydrogenase/reductase (SDR family) member 4 1.71367
RFX7 regulatory factor X, 7 1.71232
TNF tumor necrosis factor 1.70401
THAP11 THAP domain containing 11 1.70089
DCN decorin 1.69547
TBC1D5 TBC1 domain family, member 5 1.69429
KLHDC2 kelch domain containing 2 1.69145
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.68999
SLA Src-like-adaptor 1.68937
FGL2 fibrinogen-like 2 1.68899
ARFIP1 ADP-ribosylation factor interacting protein 1 1.68704
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 1.68393
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 1.68354
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.6761
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.67497
NLGN4X neuroligin 4, X-linked 1.67339
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 1.67135
AGBL2 ATP/GTP binding protein-like 2 1.67038
USP2 ubiquitin specific peptidase 2 1.66396
CLK3 CDC-like kinase 3 1.66214
MTMR2 myotubularin related protein 2 1.66076
IRF8 interferon regulatory factor 8 1.65882
PARM1 prostate androgen-regulated mucin-like protein 1 1.65767
ATM ATM serine/threonine kinase 1.65633
MEF2B myocyte enhancer factor 2B 1.65492
TMEM123 transmembrane protein 123 1.65368
HMGN1 high mobility group nucleosome binding domain 1 1.65131
LAMP3 lysosomal-associated membrane protein 3 1.64852
RPL36AL ribosomal protein L36a-like 1.64537
KCMF1 potassium channel modulatory factor 1 1.64526
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.64105
ATP9B ATPase, class II, type 9B 1.63646
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.63593
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 1.63247
FRYL FRY-like 1.63126
COMMD8 COMM domain containing 8 1.6308
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 1.62929
GCHFR GTP cyclohydrolase I feedback regulator 1.62895
CTSS cathepsin S 1.6273
TMEM126B transmembrane protein 126B 1.62391
CCDC88A coiled-coil domain containing 88A 1.61957
TNP2 transition protein 2 (during histone to protamine replacement) 1.61562
SYNE1 spectrin repeat containing, nuclear envelope 1 1.61482
TRAPPC8 trafficking protein particle complex 8 1.61349
CD27 CD27 molecule 1.60742
CD52 CD52 molecule 1.60634
TANK TRAF family member-associated NFKB activator 1.6049
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 1.60144
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 1.59772
BMX BMX non-receptor tyrosine kinase 1.59668
ZNF141 zinc finger protein 141 1.59591
STAP1 signal transducing adaptor family member 1 1.59538
THPO thrombopoietin 1.59403
CDK14 cyclin-dependent kinase 14 1.58931
ACYP1 acylphosphatase 1, erythrocyte (common) type 1.58374
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.5835
RFTN1 raftlin, lipid raft linker 1 1.58127
OFD1 oral-facial-digital syndrome 1 1.58081
RHOBTB2 Rho-related BTB domain containing 2 1.57968
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 1.57918
GRHPR glyoxylate reductase/hydroxypyruvate reductase 1.57666
WDR19 WD repeat domain 19 1.57394
NOL4 nucleolar protein 4 1.57379
RBM6 RNA binding motif protein 6 1.57325
CSK c-src tyrosine kinase 1.57198
DOK3 docking protein 3 1.57166
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.56857
TG thyroglobulin 1.5674
ZNF106 zinc finger protein 106 1.56152
BCL7B B-cell CLL/lymphoma 7B 1.55657
BTG2 BTG family, member 2 1.55651
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 1.55562
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 1.55495
GRB2 growth factor receptor-bound protein 2 1.54895
OGN osteoglycin 1.54835
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.54741
CSN3 casein kappa 1.54459
HMBOX1 homeobox containing 1 1.54349
SETD2 SET domain containing 2 1.5376
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.53661
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 1.53417
CCL4 chemokine (C-C motif) ligand 4 1.53065
HDAC1 histone deacetylase 1 1.53006
PCBP1 poly(rC) binding protein 1 1.52983
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.52813
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 1.52747
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.52659
CD81 CD81 molecule 1.52629
ABHD14A abhydrolase domain containing 14A 1.52582
PLEK pleckstrin 1.52429
DNAI1 dynein, axonemal, intermediate chain 1 1.52387
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1.52371
MED28 mediator complex subunit 28 1.52217
IFI30 interferon, gamma-inducible protein 30 1.52035
CD79A CD79a molecule, immunoglobulin-associated alpha 1.51982
FBXO34 F-box protein 34 1.51922
STAT5A signal transducer and activator of transcription 5A 1.51838
MOAP1 modulator of apoptosis 1 1.51484
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 1.51349
HLA-DMA major histocompatibility complex, class II, DM alpha 1.51289
CCDC101 coiled-coil domain containing 101 1.51282
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.51248
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.50933
TXNL4A thioredoxin-like 4A 1.50853
ZNF8 zinc finger protein 8 1.50742
MAG myelin associated glycoprotein 1.50443
ZNF586 zinc finger protein 586 1.50234
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.49934
FAM53B family with sequence similarity 53, member B 1.49905
OR3A1 olfactory receptor, family 3, subfamily A, member 1 1.49721
SPI1 Spi-1 proto-oncogene 1.49403
ZBTB1 zinc finger and BTB domain containing 1 1.49339
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.49317
KLF12 Kruppel-like factor 12 1.48989
CLMN calmin (calponin-like, transmembrane) 1.48709
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 1.48561
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 1.48436
DOCK2 dedicator of cytokinesis 2 1.4822
LRP4 low density lipoprotein receptor-related protein 4 1.47835
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.47732
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.47693
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 1.47618
USP6NL USP6 N-terminal like 1.47315
LRRK1 leucine-rich repeat kinase 1 1.47254
PHF21A PHD finger protein 21A 1.47029
E2F5 E2F transcription factor 5, p130-binding 1.46989
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 1.46764
MST1L macrophage stimulating 1-like 1.46715
LIPT1 lipoyltransferase 1 1.4643
BCL7A B-cell CLL/lymphoma 7A 1.46406
RCOR3 REST corepressor 3 1.46358
DSC1 desmocollin 1 1.4614
ACO2 aconitase 2, mitochondrial 1.46054
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 1.45867
IFT54 intraflagellar transport 54 1.45819
CD19 CD19 molecule 1.45775
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 1.45657
EPHB1 EPH receptor B1 1.45456
ZMYM6 zinc finger, MYM-type 6 1.45083
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 1.45041
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.45037
RAB30 RAB30, member RAS oncogene family 1.44842
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 1.44602
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.44533
RANGRF RAN guanine nucleotide release factor 1.44043
VGLL4 vestigial-like family member 4 1.4381
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 1.43803
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 1.43674
CETP cholesteryl ester transfer protein, plasma 1.43658
CDC40 cell division cycle 40 1.43537
LTB lymphotoxin beta (TNF superfamily, member 3) 1.4347
SLC12A8 solute carrier family 12, member 8 1.43214
JAKMIP2 janus kinase and microtubule interacting protein 2 1.42963
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.42903
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1.42843
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 1.42822
CD247 CD247 molecule 1.42661
GGCX gamma-glutamyl carboxylase 1.42629
PHF11 PHD finger protein 11 1.41708

low expression

Symbol Name Standardized Value
BMP2K BMP2 inducible kinase -3.53723
YES1 YES proto-oncogene 1, Src family tyrosine kinase -3.53287
IQCK IQ motif containing K -3.51674
GATA2 GATA binding protein 2 -3.49954
GAA glucosidase, alpha; acid -3.38427
MASP2 mannan-binding lectin serine peptidase 2 -3.26693
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -3.23742
MACF1 microtubule-actin crosslinking factor 1 -3.15922
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene -3.15231
COPZ1 coatomer protein complex, subunit zeta 1 -3.08266
NOTCH1 notch 1 -2.97725
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -2.97227
PYCR1 pyrroline-5-carboxylate reductase 1 -2.9253
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -2.87678
MTUS1 microtubule associated tumor suppressor 1 -2.86931
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.84252
HBEGF heparin-binding EGF-like growth factor -2.79378
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -2.77953
SPHAR S-phase response (cyclin related) -2.74766
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -2.7127
ENC1 ectodermal-neural cortex 1 (with BTB domain) -2.70499
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -2.68689
TSPAN6 tetraspanin 6 -2.65906
RPA4 replication protein A4, 30kDa -2.63427
TOM1 target of myb1 (chicken) -2.48926
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -2.46093
GTF2IRD1 GTF2I repeat domain containing 1 -2.45434
ETV6 ets variant 6 -2.44442
PKP4 plakophilin 4 -2.40934
MAP2K7 mitogen-activated protein kinase kinase 7 -2.38631
LGMN legumain -2.37672
ST5 suppression of tumorigenicity 5 -2.37141
IL6ST interleukin 6 signal transducer -2.36695
KRTAP5-8 keratin associated protein 5-8 -2.34836
LY6E lymphocyte antigen 6 complex, locus E -2.34829
IRX5 iroquois homeobox 5 -2.34011
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -2.33483
NDRG2 NDRG family member 2 -2.32996
MORF4L2 mortality factor 4 like 2 -2.32942
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -2.32741
KCTD15 potassium channel tetramerization domain containing 15 -2.32597
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 -2.32504
HOXD1 homeobox D1 -2.31856
ULK2 unc-51 like autophagy activating kinase 2 -2.30244
PDE4DIP phosphodiesterase 4D interacting protein -2.28337
LAMB4 laminin, beta 4 -2.2785
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -2.27842
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -2.26641
AVPI1 arginine vasopressin-induced 1 -2.26383
EI24 etoposide induced 2.4 -2.26021
RAB4A RAB4A, member RAS oncogene family -2.24954
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.23925
ST7 suppression of tumorigenicity 7 -2.23915
STK38L serine/threonine kinase 38 like -2.23246
F2R coagulation factor II (thrombin) receptor -2.22692
KIF3C kinesin family member 3C -2.21648
DHRS7B dehydrogenase/reductase (SDR family) member 7B -2.20905
NCKAP1 NCK-associated protein 1 -2.19492
MEIS3P1 Meis homeobox 3 pseudogene 1 -2.18343
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.18055
CCDC9 coiled-coil domain containing 9 -2.18028
RXRA retinoid X receptor, alpha -2.17182
VANGL1 VANGL planar cell polarity protein 1 -2.16975
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.16918
ZNF623 zinc finger protein 623 -2.14735
DLG5 discs, large homolog 5 (Drosophila) -2.14578
TP53BP2 tumor protein p53 binding protein 2 -2.14082
PECR peroxisomal trans-2-enoyl-CoA reductase -2.13656
CHPT1 choline phosphotransferase 1 -2.13145
NAV2 neuron navigator 2 -2.11766
FNDC3B fibronectin type III domain containing 3B -2.11641
NOL6 nucleolar protein 6 (RNA-associated) -2.10622
ARHGAP10 Rho GTPase activating protein 10 -2.1037
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.09772
UST uronyl-2-sulfotransferase -2.09658
PCLO piccolo presynaptic cytomatrix protein -2.09643
SORBS3 sorbin and SH3 domain containing 3 -2.09593
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled -2.09527
BMP1 bone morphogenetic protein 1 -2.08522
GSE1 Gse1 coiled-coil protein -2.08421
SRPK2 SRSF protein kinase 2 -2.07831
LRP5L low density lipoprotein receptor-related protein 5-like -2.07086
LRRC49 leucine rich repeat containing 49 -2.06856
PPT2 palmitoyl-protein thioesterase 2 -2.06225
HOXA9 homeobox A9 -2.04787
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -2.04739
PLAUR plasminogen activator, urokinase receptor -2.03381
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -2.02827
LTK leukocyte receptor tyrosine kinase -2.0217
GCA grancalcin, EF-hand calcium binding protein -2.01822
MREG melanoregulin -2.01611
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.01513
RIC8B RIC8 guanine nucleotide exchange factor B -2.01242
RND3 Rho family GTPase 3 -2.01166
ASIC3 acid sensing (proton gated) ion channel 3 -2.01129
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.00686
KIFC3 kinesin family member C3 -2.00225
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -1.99839
LRRC16A leucine rich repeat containing 16A -1.99822
LUZP1 leucine zipper protein 1 -1.99747
PDE8A phosphodiesterase 8A -1.9973
IGSF3 immunoglobulin superfamily, member 3 -1.99591
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -1.98526
KANK2 KN motif and ankyrin repeat domains 2 -1.98515
MYH10 myosin, heavy chain 10, non-muscle -1.98194
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -1.97756
DSTN destrin (actin depolymerizing factor) -1.97247
RHOB ras homolog family member B -1.97096
YBX3 Y box binding protein 3 -1.96851
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -1.96746
SPTBN1 spectrin, beta, non-erythrocytic 1 -1.95604
TSPO translocator protein (18kDa) -1.95226
ETF1 eukaryotic translation termination factor 1 -1.94924
MID1IP1 MID1 interacting protein 1 -1.94391
ZNF358 zinc finger protein 358 -1.94028
TEAD3 TEA domain family member 3 -1.92618
XK X-linked Kx blood group -1.92174
NUMA1 nuclear mitotic apparatus protein 1 -1.91897
HIPK3 homeodomain interacting protein kinase 3 -1.91838
BTBD3 BTB (POZ) domain containing 3 -1.91716
PLS3 plastin 3 -1.91494
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -1.91427
ARNTL aryl hydrocarbon receptor nuclear translocator-like -1.91336
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -1.91055
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.90791
NT5DC3 5'-nucleotidase domain containing 3 -1.90301
ADM adrenomedullin -1.90052
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -1.90014
KIAA1654 KIAA1654 protein -1.89998
GYG2 glycogenin 2 -1.89675
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -1.89218
KLF4 Kruppel-like factor 4 (gut) -1.88933
KIAA0754 KIAA0754 -1.88925
SORT1 sortilin 1 -1.88803
ACOT11 acyl-CoA thioesterase 11 -1.88778
MPZL1 myelin protein zero-like 1 -1.88007
BICC1 BicC family RNA binding protein 1 -1.87972
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -1.87614
KIAA0895 KIAA0895 -1.87424
WDFY3 WD repeat and FYVE domain containing 3 -1.87146
CST3 cystatin C -1.87029
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -1.87003
FGFR1 fibroblast growth factor receptor 1 -1.86967
PON2 paraoxonase 2 -1.86721
NOV nephroblastoma overexpressed -1.86353
ACADSB acyl-CoA dehydrogenase, short/branched chain -1.85548
CRY1 cryptochrome circadian clock 1 -1.85251
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -1.84992
BET1L Bet1 golgi vesicular membrane trafficking protein-like -1.84919
FAM65A family with sequence similarity 65, member A -1.84793
JADE3 jade family PHD finger 3 -1.84581
RAB11FIP5 RAB11 family interacting protein 5 (class I) -1.83872
GATA6 GATA binding protein 6 -1.83665
ZNF74 zinc finger protein 74 -1.83621
CTSF cathepsin F -1.83488
TSPAN9 tetraspanin 9 -1.83212
ACBD4 acyl-CoA binding domain containing 4 -1.83193
MCC mutated in colorectal cancers -1.82848
ITGB8 integrin, beta 8 -1.82547
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -1.82503
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -1.82201
CERS6 ceramide synthase 6 -1.80585
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -1.80312
BMP2 bone morphogenetic protein 2 -1.79956
NPR3 natriuretic peptide receptor 3 -1.79912
TMEM2 transmembrane protein 2 -1.78962
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -1.78732
PHKA1 phosphorylase kinase, alpha 1 (muscle) -1.78531
NFE2L3 nuclear factor, erythroid 2-like 3 -1.78098
CDYL chromodomain protein, Y-like -1.77983
ARL2 ADP-ribosylation factor-like 2 -1.77923
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -1.77825
EPHB2 EPH receptor B2 -1.77825
FSTL1 follistatin-like 1 -1.75955
CUEDC1 CUE domain containing 1 -1.75562
SCARB2 scavenger receptor class B, member 2 -1.75522
CNKSR1 connector enhancer of kinase suppressor of Ras 1 -1.75512
TRIO trio Rho guanine nucleotide exchange factor -1.75378
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -1.75364
MICALL2 MICAL-like 2 -1.75095
RPL26L1 ribosomal protein L26-like 1 -1.74654
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -1.74497
DCTD dCMP deaminase -1.74074
TEAD4 TEA domain family member 4 -1.73666
SLC2A4RG SLC2A4 regulator -1.73538
ACAD8 acyl-CoA dehydrogenase family, member 8 -1.73426
PRR5 proline rich 5 (renal) -1.73265
DSTYK dual serine/threonine and tyrosine protein kinase -1.7305
FAM117A family with sequence similarity 117, member A -1.72896
SNX9 sorting nexin 9 -1.72861
PRSS23 protease, serine, 23 -1.72825
SYNM synemin, intermediate filament protein -1.71956
ITGB5 integrin, beta 5 -1.71453
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -1.70604
FNDC8 fibronectin type III domain containing 8 -1.6961
EPHA5 EPH receptor A5 -1.69119
CYFIP1 cytoplasmic FMR1 interacting protein 1 -1.68893
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -1.68725
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -1.68715
DDAH1 dimethylarginine dimethylaminohydrolase 1 -1.68208
FBXL18 F-box and leucine-rich repeat protein 18 -1.68165
FHL2 four and a half LIM domains 2 -1.67969
FUS FUS RNA binding protein -1.67867
BOLA1 bolA family member 1 -1.67818
KRT1 keratin 1, type II -1.67749
ADAP1 ArfGAP with dual PH domains 1 -1.67369
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -1.67233
ARL4D ADP-ribosylation factor-like 4D -1.66782
RBM48 RNA binding motif protein 48 -1.66506
MTMR11 myotubularin related protein 11 -1.66445
ADCY2 adenylate cyclase 2 (brain) -1.66444
GOLM1 golgi membrane protein 1 -1.66419
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -1.66174
TBC1D12 TBC1 domain family, member 12 -1.66124
PLXNA1 plexin A1 -1.65946
MT3 metallothionein 3 -1.65742
ANK1 ankyrin 1, erythrocytic -1.65442
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -1.65219
THAP10 THAP domain containing 10 -1.64971
NCK2 NCK adaptor protein 2 -1.64918
ARID3A AT rich interactive domain 3A (BRIGHT-like) -1.64868
LITAF lipopolysaccharide-induced TNF factor -1.64804
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -1.64359
FZD6 frizzled class receptor 6 -1.64283
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.64022
TSKU tsukushi, small leucine rich proteoglycan -1.64012
L1CAM L1 cell adhesion molecule -1.64005
INSM1 insulinoma-associated 1 -1.63965
DOCK1 dedicator of cytokinesis 1 -1.6375
BAMBI BMP and activin membrane-bound inhibitor -1.63667
CRMP1 collapsin response mediator protein 1 -1.63308
ZBTB20 zinc finger and BTB domain containing 20 -1.63196
UNC13B unc-13 homolog B (C. elegans) -1.6209
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -1.6176
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.61645
LRP5 low density lipoprotein receptor-related protein 5 -1.61501
CD59 CD59 molecule, complement regulatory protein -1.61479
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -1.61469
PEPD peptidase D -1.61426
STEAP3 STEAP family member 3, metalloreductase -1.61416
MVD mevalonate (diphospho) decarboxylase -1.6116
CKAP4 cytoskeleton-associated protein 4 -1.60869
ATP11A ATPase, class VI, type 11A -1.60707
ZCCHC14 zinc finger, CCHC domain containing 14 -1.60697
SEPT8 septin 8 -1.60517
ADGRA3 adhesion G protein-coupled receptor A3 -1.60258
CADPS2 Ca++-dependent secretion activator 2 -1.60146
RHOBTB1 Rho-related BTB domain containing 1 -1.59706
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) -1.5954
TEX2 testis expressed 2 -1.59535
IGFBP3 insulin-like growth factor binding protein 3 -1.59365
SCARA3 scavenger receptor class A, member 3 -1.59249
ACTN1 actinin, alpha 1 -1.59137
SEPW1 selenoprotein W, 1 -1.58988
ARL4A ADP-ribosylation factor-like 4A -1.58817
IGF2R insulin-like growth factor 2 receptor -1.58194
HPCAL1 hippocalcin-like 1 -1.58053
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -1.57666
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.57658
IFRD1 interferon-related developmental regulator 1 -1.57571
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 -1.57383
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 -1.57002
PUF60 poly-U binding splicing factor 60KDa -1.56734
STARD13 StAR-related lipid transfer (START) domain containing 13 -1.56666
PSPN persephin -1.56442
KCTD3 potassium channel tetramerization domain containing 3 -1.56343
PCDHB1 protocadherin beta 1 -1.56329
FJX1 four jointed box 1 (Drosophila) -1.55942
FAM64A family with sequence similarity 64, member A -1.55758
PARD3 par-3 family cell polarity regulator -1.55664
IKZF2 IKAROS family zinc finger 2 (Helios) -1.55656
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -1.555
PNPLA3 patatin-like phospholipase domain containing 3 -1.55423
ZFHX2 zinc finger homeobox 2 -1.55316
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -1.55068
ABHD4 abhydrolase domain containing 4 -1.54904
ADGRB3 adhesion G protein-coupled receptor B3 -1.54786
CAPN2 calpain 2, (m/II) large subunit -1.54538
RAB32 RAB32, member RAS oncogene family -1.54437
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -1.54409
ADORA2B adenosine A2b receptor -1.53752
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -1.53439
HSPA12A heat shock 70kDa protein 12A -1.53244
CXCL6 chemokine (C-X-C motif) ligand 6 -1.53198
PTPRF protein tyrosine phosphatase, receptor type, F -1.52818
FBLN1 fibulin 1 -1.52374
NCLN nicalin -1.52254
BEX1 brain expressed, X-linked 1 -1.52156
ITGAV integrin, alpha V -1.52055
PARVA parvin, alpha -1.51995
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -1.51867
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -1.51704
AHNAK AHNAK nucleoprotein -1.51519
VGF VGF nerve growth factor inducible -1.51511
RREB1 ras responsive element binding protein 1 -1.51473
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -1.51319
KLF10 Kruppel-like factor 10 -1.5131
PAX1 paired box 1 -1.51268
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -1.5103
MYOM1 myomesin 1 -1.50918
GBP2 guanylate binding protein 2, interferon-inducible -1.50434
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -1.50279
MMRN2 multimerin 2 -1.49884
EPAS1 endothelial PAS domain protein 1 -1.49663
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -1.49636
OR10H2 olfactory receptor, family 10, subfamily H, member 2 -1.49509
G6PC2 glucose-6-phosphatase, catalytic, 2 -1.49456
FERMT2 fermitin family member 2 -1.49455
GAS8 growth arrest-specific 8 -1.48895
ADORA1 adenosine A1 receptor -1.48679
HIST2H2BE histone cluster 2, H2be -1.48427
CXADR coxsackie virus and adenovirus receptor -1.48408
FLNA filamin A, alpha -1.48224
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -1.48185
IER2 immediate early response 2 -1.48055
PCSK6 proprotein convertase subtilisin/kexin type 6 -1.48006
BACE2 beta-site APP-cleaving enzyme 2 -1.48001
ERMAP erythroblast membrane-associated protein (Scianna blood group) -1.47934
POLR1B polymerase (RNA) I polypeptide B, 128kDa -1.47411
PCGF2 polycomb group ring finger 2 -1.474
PVRL3 poliovirus receptor-related 3 -1.47373
AKR1C1 aldo-keto reductase family 1, member C1 -1.47316
EGFR epidermal growth factor receptor -1.46907
KLF9 Kruppel-like factor 9 -1.46833
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -1.46672
GLCE glucuronic acid epimerase -1.46616
ZNF217 zinc finger protein 217 -1.46603
WLS wntless Wnt ligand secretion mediator -1.46499
SFTPC surfactant protein C -1.46289
AMOTL2 angiomotin like 2 -1.46152
GCKR glucokinase (hexokinase 4) regulator -1.46072
TYRO3 TYRO3 protein tyrosine kinase -1.45703
RYK receptor-like tyrosine kinase -1.45263
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -1.45078
ATXN1 ataxin 1 -1.4504
MED26 mediator complex subunit 26 -1.44807
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -1.4476
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -1.44733
HRH4 histamine receptor H4 -1.4468
ARCN1 archain 1 -1.44488
KIAA1598 -1.44325
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -1.44212
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -1.43916
KDM5B lysine (K)-specific demethylase 5B -1.43911
MYBPC3 myosin binding protein C, cardiac -1.43718
ZMYND11 zinc finger, MYND-type containing 11 -1.43577
NPY4R neuropeptide Y receptor Y4 -1.43535
SH3BP4 SH3-domain binding protein 4 -1.43513
NEFL neurofilament, light polypeptide -1.43509
LIMS1 LIM and senescent cell antigen-like domains 1 -1.43437
TESK2 testis-specific kinase 2 -1.43246
CLDN11 claudin 11 -1.43213
AP3B2 adaptor-related protein complex 3, beta 2 subunit -1.42902
PXN paxillin -1.42714
SNX24 sorting nexin 24 -1.4256
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -1.42417
N4BP2L2-IT2 N4BPL2 intronic transcript 2 -1.4241
SOCS5 suppressor of cytokine signaling 5 -1.42226
OSGIN1 oxidative stress induced growth inhibitor 1 -1.42195
EGFL6 EGF-like-domain, multiple 6 -1.42138
LAPTM4B lysosomal protein transmembrane 4 beta -1.41686