KCNJ6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description potassium channel, inwardly rectifying subfamily J, member 6|This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015] (NCBI Entrez Gene Database, 3763)
External Link https://ncbi.nlm.nih.gov/gene/3763
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Genes

499 genes differentially expressed following the KCNJ6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0132049
SMC1A structural maintenance of chromosomes 1A 0.0125365
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0124898
LTF lactotransferrin 0.0122446
GSTA1 glutathione S-transferase alpha 1 0.0117467
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.0116768
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0116403
NUSAP1 nucleolar and spindle associated protein 1 0.0115501
FABP7 fatty acid binding protein 7, brain 0.0114605
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0113328
PRKCA protein kinase C, alpha 0.0111168
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0105235
IQGAP2 IQ motif containing GTPase activating protein 2 0.0104985
OLFM4 olfactomedin 4 0.0104824
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.0104641
ANXA6 annexin A6 0.0104212
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0103062
XIC X chromosome inactivation center 0.0102747
NTS neurotensin 0.0101749
PCP4 Purkinje cell protein 4 0.0101454
RAD23B RAD23 homolog B (S. cerevisiae) 0.0101247
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00988265
LAPTM4B lysosomal protein transmembrane 4 beta 0.00987287
KIF15 kinesin family member 15 0.00982205
PRMT1 protein arginine methyltransferase 1 0.00977928
TRMT5 tRNA methyltransferase 5 0.00960414
MMP12 matrix metallopeptidase 12 0.00947679
ENO1 enolase 1, (alpha) 0.0093959
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00933982
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00932102
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00929917
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.00913798
KIF20A kinesin family member 20A 0.0091084
FBXO11 F-box protein 11 0.00910364
LGALS13 lectin, galactoside-binding, soluble, 13 0.0091006
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00909615
CCNA2 cyclin A2 0.00907981
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00889395
PSIP1 PC4 and SFRS1 interacting protein 1 0.00877566
LMNB1 lamin B1 0.00869428
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.00868253
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00867896
NES nestin 0.00867382
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00864328
SRSF1 serine/arginine-rich splicing factor 1 0.00863917
PNMA2 paraneoplastic Ma antigen 2 0.00859261
PGD phosphogluconate dehydrogenase 0.00857071
ALB albumin 0.00854249
GANAB glucosidase, alpha; neutral AB 0.00851893
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00847445
DPYD dihydropyrimidine dehydrogenase 0.00847232
BMP4 bone morphogenetic protein 4 0.0084689
SPC25 SPC25, NDC80 kinetochore complex component 0.00845209
KIF11 kinesin family member 11 0.00833009
HMGB2 high mobility group box 2 0.00830265
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00825353
TUBB2A tubulin, beta 2A class IIa 0.0082513
CAPZB capping protein (actin filament) muscle Z-line, beta 0.00823676
PAH phenylalanine hydroxylase 0.00819113
BIRC5 baculoviral IAP repeat containing 5 0.00808434
NIBAN1 niban apoptosis regulator 1 0.00806323
NEK2 NIMA-related kinase 2 0.0080578
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00803287
MGP matrix Gla protein 0.00801302
WFDC2 WAP four-disulfide core domain 2 0.00800499
PGAM1 phosphoglycerate mutase 1 (brain) 0.00797308
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.0079573
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00795248
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00795108
COL1A2 collagen, type I, alpha 2 0.00793144
BEX1 brain expressed, X-linked 1 0.00782844
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00782468
IGFBP1 insulin-like growth factor binding protein 1 0.00781495
INSIG1 insulin induced gene 1 0.00777467
GSTA4 glutathione S-transferase alpha 4 0.00773837
SNX7 sorting nexin 7 0.00771131
RNF167 ring finger protein 167 0.00771115
ANXA5 annexin A5 0.00766482
HP haptoglobin 0.00764917
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00764446
TMX4 thioredoxin-related transmembrane protein 4 0.00762621
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.00762103
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00759695
PBX1 pre-B-cell leukemia homeobox 1 0.00758092
DMD dystrophin 0.00757023
MGAM maltase-glucoamylase 0.00754223
KRT13 keratin 13, type I 0.00746949
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00743377
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00742382
PKM pyruvate kinase, muscle 0.00741334
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00739356
TOX thymocyte selection-associated high mobility group box 0.00738994
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 0.00738221
FOXG1 forkhead box G1 0.00737938
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00736065
FLNA filamin A, alpha 0.0072855
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00725944
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00724644
DPYSL2 dihydropyrimidinase-like 2 0.00723196
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.00722502
ENO2 enolase 2 (gamma, neuronal) 0.00720887
CD69 CD69 molecule 0.00719158
NLGN4X neuroligin 4, X-linked 0.00718857
TMEM38B transmembrane protein 38B 0.00716538
OIP5 Opa interacting protein 5 0.00715428
DPY19L2P2 DPY19L2 pseudogene 2 0.00709826
NCKAP1L NCK-associated protein 1-like 0.0070966
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00704157
HMGN2 high mobility group nucleosomal binding domain 2 0.00703921
RRM2 ribonucleotide reductase M2 0.00703872
APOC3 apolipoprotein C-III 0.00703053
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00702664
EPAS1 endothelial PAS domain protein 1 0.0070123
CEP55 centrosomal protein 55kDa 0.00700881
LBR lamin B receptor 0.00700289
MTTP microsomal triglyceride transfer protein 0.00700267
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.00698583
PRUNE2 prune homolog 2 (Drosophila) 0.00698333
TPI1 triosephosphate isomerase 1 0.00697413
SEC23A Sec23 homolog A (S. cerevisiae) 0.00696379
MSX1 msh homeobox 1 0.00695678
KRT15 keratin 15, type I 0.0069531
PRR7 proline rich 7 (synaptic) 0.00694234
OGN osteoglycin 0.00689309
AFP alpha-fetoprotein 0.00688682
PRPF19 pre-mRNA processing factor 19 0.00687131
CLU clusterin 0.0068346
NDP Norrie disease (pseudoglioma) 0.00682014
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00678502
RRAGA Ras-related GTP binding A 0.00677817
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00677689
MMRN1 multimerin 1 0.00676823
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0067615
AK4 adenylate kinase 4 0.00675132
ACOX2 acyl-CoA oxidase 2, branched chain 0.00673555
LTA4H leukotriene A4 hydrolase 0.0067096
APOB apolipoprotein B 0.00670284
GLUL glutamate-ammonia ligase 0.00668848
MATN2 matrilin 2 0.00667482
TMED9 transmembrane emp24 protein transport domain containing 9 0.00665082
PGC progastricsin (pepsinogen C) 0.00662378
RFC2 replication factor C (activator 1) 2, 40kDa 0.00659967
SMC2 structural maintenance of chromosomes 2 0.00658487
PSPH phosphoserine phosphatase 0.00657203
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.00653423
KHK ketohexokinase (fructokinase) 0.00653378
FUS FUS RNA binding protein 0.0065181
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00651138
KIF18B kinesin family member 18B 0.006486
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00646932
ARHGAP26 Rho GTPase activating protein 26 0.00646686
CAPRIN1 cell cycle associated protein 1 0.0064664
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00646566
COPA coatomer protein complex, subunit alpha 0.00645739
PTN pleiotrophin 0.00645661
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00645271
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00644747
CLEC2D C-type lectin domain family 2, member D 0.0064467
TBL1X transducin (beta)-like 1X-linked 0.00643598
RMI1 RecQ mediated genome instability 1 0.00642338
DLK1 delta-like 1 homolog (Drosophila) 0.00642202
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00642178
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00642112
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00641826
PDIA3 protein disulfide isomerase family A, member 3 0.00640358
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.00639748
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.00639019
DBF4 DBF4 zinc finger 0.00638556
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.00638461
YEATS4 YEATS domain containing 4 0.00636642
AURKB aurora kinase B 0.00636518
CAPN6 calpain 6 0.00635112
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.00634349
APOA2 apolipoprotein A-II 0.00633387
MDM1 Mdm1 nuclear protein homolog (mouse) 0.00632855
SPAG5 sperm associated antigen 5 0.0063285
UNC119B unc-119 homolog B (C. elegans) 0.00631764
GAS2 growth arrest-specific 2 0.00631307
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00628997
GPI glucose-6-phosphate isomerase 0.00628746
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00627898
FABP1 fatty acid binding protein 1, liver 0.00627493
DZIP1 DAZ interacting zinc finger protein 1 0.00626827
ALDOB aldolase B, fructose-bisphosphate 0.00626153
TYMS thymidylate synthetase 0.00625687
GLOD4 glyoxalase domain containing 4 0.00624367
ORM1 orosomucoid 1 0.00623968
FBXO5 F-box protein 5 0.0062358
ACP6 acid phosphatase 6, lysophosphatidic 0.00623069
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.0062023
MOXD1 monooxygenase, DBH-like 1 0.0061968
SERBP1 SERPINE1 mRNA binding protein 1 0.00619672
RAB5C RAB5C, member RAS oncogene family 0.00618803
ACTL6A actin-like 6A 0.00618451
SI sucrase-isomaltase (alpha-glucosidase) 0.0061843
ACTB actin, beta 0.00618388
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00618316
NDC80 NDC80 kinetochore complex component 0.00617792
TNIK TRAF2 and NCK interacting kinase 0.00617554
SYT11 synaptotagmin XI 0.00614327
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00614185
RESF1 retroelement silencing factor 1 0.00613381
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 0.00613295
USP1 ubiquitin specific peptidase 1 0.0060846
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00608155
CDK1 cyclin-dependent kinase 1 0.00606546
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00606125
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.00605955
G6PC glucose-6-phosphatase, catalytic subunit 0.00605372
SET SET nuclear proto-oncogene 0.00603118
PXMP2 peroxisomal membrane protein 2, 22kDa 0.00600758
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00600534
F12 coagulation factor XII (Hageman factor) 0.00600117
STMN1 stathmin 1 0.00598987
CDKN3 cyclin-dependent kinase inhibitor 3 0.00597562
RXRA retinoid X receptor, alpha 0.00596516
WDR61 WD repeat domain 61 0.00593265
TARDBP TAR DNA binding protein 0.00591887
HMGB1 high mobility group box 1 0.00591832
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0059088
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.00590364
HMGN5 high mobility group nucleosome binding domain 5 0.00589232
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.00584722
RBL1 retinoblastoma-like 1 0.00583413
CALML4 calmodulin-like 4 0.00582828
MAGED1 melanoma antigen family D1 0.00579664
FGG fibrinogen gamma chain 0.0057955
CAND1 cullin-associated and neddylation-dissociated 1 0.00579173
RAD51AP1 RAD51 associated protein 1 0.0057913
TMPO thymopoietin 0.00579077
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.00578903
RBBP4 retinoblastoma binding protein 4 0.00578857
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.0057815
DCPS decapping enzyme, scavenger 0.00577307
PSRC1 proline/serine-rich coiled-coil 1 0.00574862
CES1 carboxylesterase 1 0.00574715
GPM6B glycoprotein M6B 0.00574595
KIF18A kinesin family member 18A 0.00572107
XPO7 exportin 7 0.00571244
NPM3 nucleophosmin/nucleoplasmin 3 0.00571169
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.00568748
KIF1B kinesin family member 1B 0.00568705
FGFR3 fibroblast growth factor receptor 3 0.00567856
PFKL phosphofructokinase, liver 0.00567714
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00567586
KIF5C kinesin family member 5C 0.00567213
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00566761
SYNM synemin, intermediate filament protein 0.00566282
MKI67 marker of proliferation Ki-67 0.00564633
EIF4A1 eukaryotic translation initiation factor 4A1 0.00563302

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0203535
RND3 Rho family GTPase 3 -0.0183476
PLAAT3 phospholipase A and acyltransferase 3 -0.0177702
IFI27 interferon, alpha-inducible protein 27 -0.0165612
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0161219
IFI6 interferon, alpha-inducible protein 6 -0.0151633
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0146836
TFPI2 tissue factor pathway inhibitor 2 -0.0144129
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0143551
MX1 MX dynamin-like GTPase 1 -0.0140108
H1-2 H1.2 linker histone, cluster member -0.0135489
WDR7 WD repeat domain 7 -0.0134538
HSPA1A heat shock 70kDa protein 1A -0.0133576
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0132964
MT1M metallothionein 1M -0.0128065
TRIM22 tripartite motif containing 22 -0.0124049
ADIRF adipogenesis regulatory factor -0.0123657
NNMT nicotinamide N-methyltransferase -0.0123624
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.0121556
PPARG peroxisome proliferator-activated receptor gamma -0.0117862
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0117513
IRF7 interferon regulatory factor 7 -0.0116821
HOPX HOP homeobox -0.0116626
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0116486
ISG15 ISG15 ubiquitin-like modifier -0.0116455
LXN latexin -0.0115258
DOCK9 dedicator of cytokinesis 9 -0.0115228
MIR22HG MIR22 host gene -0.0114596
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0111476
INHBA inhibin, beta A -0.0110732
ARHGAP29 Rho GTPase activating protein 29 -0.0110702
ZMAT3 zinc finger, matrin-type 3 -0.0110513
MGLL monoglyceride lipase -0.0109623
FABP4 fatty acid binding protein 4, adipocyte -0.0109495
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0108813
CD36 CD36 molecule (thrombospondin receptor) -0.0108169
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0107351
KLF6 Kruppel-like factor 6 -0.0106405
KDM5D lysine (K)-specific demethylase 5D -0.010625
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0105925
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.0105527
HSPB8 heat shock 22kDa protein 8 -0.0104491
MT1F metallothionein 1F -0.0103866
RPS27L ribosomal protein S27-like -0.010236
LIMCH1 LIM and calponin homology domains 1 -0.0102069
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.0102055
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.0102007
CRYAB crystallin, alpha B -0.0101379
ZNF91 zinc finger protein 91 -0.0100547
MT1X metallothionein 1X -0.0100468
HIST1H2AC histone cluster 1, H2ac -0.00998629
HTRA1 HtrA serine peptidase 1 -0.00995698
SIK1 salt-inducible kinase 1 -0.00993236
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00992298
GDF15 growth differentiation factor 15 -0.00987406
SLC38A1 solute carrier family 38, member 1 -0.00985934
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00982486
NXN nucleoredoxin -0.00977874
MVP major vault protein -0.00969891
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0094945
PERP PERP, TP53 apoptosis effector -0.00947172
THBS2 thrombospondin 2 -0.0094136
MT1G metallothionein 1G -0.00940226
HMOX1 heme oxygenase 1 -0.00939023
HBD hemoglobin, delta -0.00937715
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00930994
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0092448
GJA1 gap junction protein, alpha 1, 43kDa -0.00922809
IFI44L interferon-induced protein 44-like -0.00921236
IER5 immediate early response 5 -0.009065
OPTN optineurin -0.00897028
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00894675
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00892737
DUSP5 dual specificity phosphatase 5 -0.00890272
G0S2 G0/G1 switch 2 -0.00888788
FN1 fibronectin 1 -0.00888762
PXDC1 PX domain containing 1 -0.00884494
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00876367
ASS1 argininosuccinate synthase 1 -0.00875202
CFB complement factor B -0.00870971
TPD52 tumor protein D52 -0.00870768
IPO13 importin 13 -0.0086757
KLK10 kallikrein-related peptidase 10 -0.00866967
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00862327
AMOTL2 angiomotin like 2 -0.00862252
BTG2 BTG family, member 2 -0.00856603
AKAP8 A kinase (PRKA) anchor protein 8 -0.00854702
MMP9 matrix metallopeptidase 9 -0.00853884
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00850081
SCGB2A2 secretoglobin, family 2A, member 2 -0.00849072
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00848101
SEPTIN4 septin 4 -0.00841698
RRAGC Ras-related GTP binding C -0.00841082
DCN decorin -0.00840467
FHL2 four and a half LIM domains 2 -0.00840362
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00839873
ADM adrenomedullin -0.00828848
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00827248
TSPAN13 tetraspanin 13 -0.00825811
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00823952
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00822387
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00822364
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0082175
KLK5 kallikrein-related peptidase 5 -0.00819544
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00812305
QPCT glutaminyl-peptide cyclotransferase -0.00811684
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00810069
SLC38A2 solute carrier family 38, member 2 -0.00809236
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.0080892
HIST1H2BK histone cluster 1, H2bk -0.0080275
GREM1 gremlin 1, DAN family BMP antagonist -0.00801038
TTC39A tetratricopeptide repeat domain 39A -0.0080086
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00798324
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00797187
ATF3 activating transcription factor 3 -0.00796694
IRS1 insulin receptor substrate 1 -0.00796507
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00796436
HIST1H2BD histone cluster 1, H2bd -0.00795776
AREG amphiregulin -0.0079546
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00794129
CA2 carbonic anhydrase II -0.00793522
SNAI2 snail family zinc finger 2 -0.00792448
FTH1 ferritin, heavy polypeptide 1 -0.00791933
SCGB1D2 secretoglobin, family 1D, member 2 -0.00789687
NVL nuclear VCP-like -0.00788645
PPL periplakin -0.00787946
SOWAHC sosondowah ankyrin repeat domain family member C -0.00786859
WWC1 WW and C2 domain containing 1 -0.00785772
BEX4 brain expressed, X-linked 4 -0.00784996
TUFT1 tuftelin 1 -0.00784979
VAMP8 vesicle-associated membrane protein 8 -0.0078328
NT5E 5'-nucleotidase, ecto (CD73) -0.00782581
UPK1B uroplakin 1B -0.00778669
PLAU plasminogen activator, urokinase -0.00778485
FILIP1L filamin A interacting protein 1-like -0.00775216
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00772678
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00772087
PRSS23 protease, serine, 23 -0.00770705
APOD apolipoprotein D -0.00770515
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00770103
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00769405
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00766356
ACOT13 acyl-CoA thioesterase 13 -0.00763208
AHNAK AHNAK nucleoprotein -0.0076249
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00761527
ISG20 interferon stimulated exonuclease gene 20kDa -0.00758548
ANXA1 annexin A1 -0.00757579
AHR aryl hydrocarbon receptor -0.00756485
ZBED2 zinc finger, BED-type containing 2 -0.00756237
MX2 MX dynamin-like GTPase 2 -0.00750629
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.00749447
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00746696
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00746002
SKAP2 src kinase associated phosphoprotein 2 -0.00743634
COL5A2 collagen, type V, alpha 2 -0.00742341
GAS6 growth arrest-specific 6 -0.00741841
CCNE1 cyclin E1 -0.00740221
AVPI1 arginine vasopressin-induced 1 -0.00738886
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00735839
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00734431
EZR ezrin -0.0073421
COL10A1 collagen, type X, alpha 1 -0.00733549
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00733075
UROD uroporphyrinogen decarboxylase -0.00731068
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00730697
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -0.00730534
TSC22D2 TSC22 domain family, member 2 -0.00730453
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00728595
PTS 6-pyruvoyltetrahydropterin synthase -0.00727429
HSPA2 heat shock 70kDa protein 2 -0.00725915
MXRA5 matrix-remodelling associated 5 -0.00723529
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00721445
OSBPL3 oxysterol binding protein-like 3 -0.00719317
SGK1 serum/glucocorticoid regulated kinase 1 -0.00718034
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.00715371
PLSCR3 phospholipid scramblase 3 -0.00714344
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00713507
MT1H metallothionein 1H -0.00713216
TSPAN1 tetraspanin 1 -0.007117
DEFB1 defensin, beta 1 -0.00710824
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00710375
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00709844
MT1HL1 metallothionein 1H-like 1 -0.00706442
WSB1 WD repeat and SOCS box containing 1 -0.00706012
IFI44 interferon-induced protein 44 -0.00704308
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00704249
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00703753
APOL1 apolipoprotein L, 1 -0.00703726
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00703312
RGS16 regulator of G-protein signaling 16 -0.00703274
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00701946
YPEL5 yippee-like 5 (Drosophila) -0.00701427
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00699394
NEBL nebulette -0.00699039
BID BH3 interacting domain death agonist -0.00698291
MRPL18 mitochondrial ribosomal protein L18 -0.0069749
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -0.00696815
TMEM140 transmembrane protein 140 -0.00696751
PTK2 protein tyrosine kinase 2 -0.00694142
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.0069249
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00692231
KLF4 Kruppel-like factor 4 (gut) -0.00691259
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00690819
CLIC5 chloride intracellular channel 5 -0.00686616
CCL19 chemokine (C-C motif) ligand 19 -0.00685272
LUM lumican -0.00685064
BLNK B-cell linker -0.00684118
MT1E metallothionein 1E -0.00683889
BCAS1 breast carcinoma amplified sequence 1 -0.00683128
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.0068226
RGCC regulator of cell cycle -0.00681867
BIK BCL2-interacting killer (apoptosis-inducing) -0.00680634
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00679389
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00678105
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00675859
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00672434
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00671295
UFM1 ubiquitin-fold modifier 1 -0.00670579
RHOD ras homolog family member D -0.00669178
REXO2 RNA exonuclease 2 -0.00668692
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00667522
IL1B interleukin 1, beta -0.00666577
SASH1 SAM and SH3 domain containing 1 -0.0066624
RBM47 RNA binding motif protein 47 -0.0066608
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00665725
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00665625
OSBPL1A oxysterol binding protein-like 1A -0.00664911
BICC1 BicC family RNA binding protein 1 -0.00663905
MYO6 myosin VI -0.00663214
ZC3H12A zinc finger CCCH-type containing 12A -0.00662518
CTSD cathepsin D -0.00661627
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00660958
LCN2 lipocalin 2 -0.0065982
BAMBI BMP and activin membrane-bound inhibitor -0.00659337
RFTN1 raftlin, lipid raft linker 1 -0.00657054
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00655206
CLTB clathrin, light chain B -0.00654884
MYRF myelin regulatory factor -0.00654671
IL6 interleukin 6 -0.00654664
S100A14 S100 calcium binding protein A14 -0.00653767
BCAR3 breast cancer anti-estrogen resistance 3 -0.00649839
GRB7 growth factor receptor-bound protein 7 -0.00649715
EIF5B eukaryotic translation initiation factor 5B -0.00649708
IGF1R insulin-like growth factor 1 receptor -0.00648807
KRT7 keratin 7, type II -0.00648395
MT2A metallothionein 2A -0.00647957
AKR1C2 aldo-keto reductase family 1, member C2 -0.00646269
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.0064533
LYPLA1 lysophospholipase I -0.00645276