| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | potassium channel, voltage gated KQT-like subfamily Q, member 1|This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 3784) |
| External Link | https://ncbi.nlm.nih.gov/gene/3784 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the KCNQ1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0122759 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0106169 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0092494 |
| XIC | X chromosome inactivation center | 0.00922535 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00879704 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0087454 |
| C1S | complement component 1, s subcomponent | 0.00827077 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0074645 |
| OLFML2A | olfactomedin-like 2A | 0.00743671 |
| MYOF | myoferlin | 0.0072182 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00721097 |
| PPL | periplakin | 0.00711662 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0070374 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00702271 |
| SPRR2B | small proline-rich protein 2B | 0.00702078 |
| EMP1 | epithelial membrane protein 1 | 0.00696979 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00695131 |
| ADIRF | adipogenesis regulatory factor | 0.00694722 |
| STC2 | stanniocalcin 2 | 0.00688643 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00678894 |
| KLK6 | kallikrein-related peptidase 6 | 0.006766 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00676356 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00671529 |
| TRIB2 | tribbles pseudokinase 2 | 0.00670656 |
| KRT17 | keratin 17, type I | 0.00662266 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00657496 |
| CP | ceruloplasmin (ferroxidase) | 0.00656313 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00654676 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00648989 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00646372 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00646241 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00642282 |
| KLK10 | kallikrein-related peptidase 10 | 0.00637398 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00632751 |
| LIF | leukemia inhibitory factor | 0.00629871 |
| PLBD1 | phospholipase B domain containing 1 | 0.0062139 |
| IFI44L | interferon-induced protein 44-like | 0.0062031 |
| SFN | stratifin | 0.00619941 |
| FMOD | fibromodulin | 0.00617934 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00615482 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00602517 |
| KRT6A | keratin 6A, type II | 0.00599946 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00599805 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00599052 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00593701 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.0059191 |
| DIPK1A | divergent protein kinase domain 1A | 0.00591378 |
| C3 | complement component 3 | 0.00587408 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00584019 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00583217 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00581273 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00577295 |
| S100A10 | S100 calcium binding protein A10 | 0.00574932 |
| S100A9 | S100 calcium binding protein A9 | 0.00574818 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00571412 |
| CFB | complement factor B | 0.00568886 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00568847 |
| XAF1 | XIAP associated factor 1 | 0.00568212 |
| ASPA | aspartoacylase | 0.00556351 |
| TMEM176B | transmembrane protein 176B | 0.00552791 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00546179 |
| COL5A2 | collagen, type V, alpha 2 | 0.00544655 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00543368 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00542603 |
| REXO2 | RNA exonuclease 2 | 0.00536897 |
| ATF3 | activating transcription factor 3 | 0.00535992 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00535598 |
| MXRA5 | matrix-remodelling associated 5 | 0.00532295 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00529046 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00527428 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00527045 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00526754 |
| TSPAN8 | tetraspanin 8 | 0.00526419 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.00523651 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00523086 |
| LOXL1 | lysyl oxidase-like 1 | 0.0052301 |
| S100A2 | S100 calcium binding protein A2 | 0.00522417 |
| COL5A1 | collagen, type V, alpha 1 | 0.00521846 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00520293 |
| C1R | complement component 1, r subcomponent | 0.00516719 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0051576 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00515057 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00514723 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00513816 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00513163 |
| FN1 | fibronectin 1 | 0.00512569 |
| RGCC | regulator of cell cycle | 0.00511507 |
| PRSS23 | protease, serine, 23 | 0.00511212 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0051075 |
| RUNX1 | runt-related transcription factor 1 | 0.0051034 |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 0.00509682 |
| GPATCH8 | G patch domain containing 8 | 0.00508984 |
| TGFB3 | transforming growth factor, beta 3 | 0.00507829 |
| TSPAN3 | tetraspanin 3 | 0.00505746 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00502017 |
| TGM2 | transglutaminase 2 | 0.00500097 |
| AHNAK | AHNAK nucleoprotein | 0.00498126 |
| TRIM29 | tripartite motif containing 29 | 0.00494081 |
| PTN | pleiotrophin | 0.00493936 |
| PLK2 | polo-like kinase 2 | 0.00493077 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00491944 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00491624 |
| CTTN | cortactin | 0.00491565 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00489685 |
| IER5 | immediate early response 5 | 0.00487222 |
| ITGB4 | integrin, beta 4 | 0.00486298 |
| S100A7 | S100 calcium binding protein A7 | 0.00485453 |
| NOTCH2NL | notch 2 N-terminal like | 0.00485358 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00485222 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00484102 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.00483705 |
| COL1A1 | collagen, type I, alpha 1 | 0.0048336 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00482673 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0048041 |
| TCF4 | transcription factor 4 | 0.00478651 |
| SPRR1A | small proline-rich protein 1A | 0.00478304 |
| COG7 | component of oligomeric golgi complex 7 | 0.00476641 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 0.00476232 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00475058 |
| ABLIM1 | actin binding LIM protein 1 | 0.00472372 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00471394 |
| TRIM16 | tripartite motif containing 16 | 0.00469869 |
| LHFP | lipoma HMGIC fusion partner | 0.00468692 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00468372 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00465245 |
| ASS1 | argininosuccinate synthase 1 | 0.00464962 |
| PLS1 | plastin 1 | 0.00464539 |
| HMOX1 | heme oxygenase 1 | 0.00463512 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0046308 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00462618 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00461788 |
| PLAU | plasminogen activator, urokinase | 0.00460527 |
| BLVRB | biliverdin reductase B | 0.00459353 |
| DUSP5 | dual specificity phosphatase 5 | 0.00458863 |
| LAMB3 | laminin, beta 3 | 0.00458614 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00457502 |
| NAV3 | neuron navigator 3 | 0.00457259 |
| KRT6B | keratin 6B, type II | 0.00457097 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00453899 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00452427 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.0045136 |
| ABHD4 | abhydrolase domain containing 4 | 0.00449925 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | 0.00449443 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00447927 |
| PALLD | palladin, cytoskeletal associated protein | 0.00447407 |
| EZR | ezrin | 0.00447398 |
| KRT14 | keratin 14, type I | 0.00446837 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0044617 |
| SPRR1B | small proline-rich protein 1B | 0.00445957 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00445218 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00444864 |
| AMOTL2 | angiomotin like 2 | 0.00444723 |
| KRT16 | keratin 16, type I | 0.00444578 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00443415 |
| HTRA1 | HtrA serine peptidase 1 | 0.00442406 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00442356 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.0044225 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00441153 |
| ECM1 | extracellular matrix protein 1 | 0.00440548 |
| MX1 | MX dynamin-like GTPase 1 | 0.00438623 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00438585 |
| EFNB2 | ephrin-B2 | 0.00438573 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00437287 |
| DUSP14 | dual specificity phosphatase 14 | 0.00435625 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00434539 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.0043333 |
| FADS3 | fatty acid desaturase 3 | 0.00432719 |
| RND3 | Rho family GTPase 3 | 0.00431571 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00431443 |
| NMB | neuromedin B | 0.0043073 |
| ATF4 | activating transcription factor 4 | 0.00430212 |
| HOPX | HOP homeobox | 0.00429989 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00429296 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.0042885 |
| DEFB4A | defensin, beta 4A | 0.0042858 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | 0.00428274 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00426861 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00425521 |
| TNS3 | tensin 3 | 0.00424777 |
| SPATA20 | spermatogenesis associated 20 | 0.00424756 |
| FBLN1 | fibulin 1 | 0.00424084 |
| TGM1 | transglutaminase 1 | 0.0042269 |
| MITF | microphthalmia-associated transcription factor | 0.00422665 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00422446 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00422333 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00421786 |
| CFDP1 | craniofacial development protein 1 | 0.00420602 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00420591 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00420343 |
| NISCH | nischarin | 0.0041954 |
| MVP | major vault protein | 0.00419106 |
| NXN | nucleoredoxin | 0.00419051 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00418386 |
| ASPN | asporin | 0.00418363 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00418145 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00416856 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00415416 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00414797 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00413391 |
| MYO1B | myosin IB | 0.00413303 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00412624 |
| AOC1 | amine oxidase, copper containing 1 | 0.00411958 |
| FAM193B | family with sequence similarity 193, member B | 0.00411293 |
| PLXDC1 | plexin domain containing 1 | 0.00410504 |
| S100A14 | S100 calcium binding protein A14 | 0.00410279 |
| GATA6 | GATA binding protein 6 | 0.00409835 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00409675 |
| AIM2 | absent in melanoma 2 | 0.00409212 |
| TRIM36 | tripartite motif containing 36 | 0.00408614 |
| DEFB1 | defensin, beta 1 | 0.004072 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00407178 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00407101 |
| TREM2 | triggering receptor expressed on myeloid cells 2 | 0.00406699 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00406189 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0040588 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00404635 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00404288 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00404216 |
| HLA-B | major histocompatibility complex, class I, B | 0.004018 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00401679 |
| DST | dystonin | 0.00401512 |
| CRNN | cornulin | 0.00400923 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00400747 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00400745 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00400691 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00399978 |
| CLTB | clathrin, light chain B | 0.0039965 |
| GPX2 | glutathione peroxidase 2 | 0.00398925 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00398096 |
| STK38 | serine/threonine kinase 38 | 0.0039791 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00396899 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00396812 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0039464 |
| MMP1 | matrix metallopeptidase 1 | 0.00393787 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00393556 |
| SLC46A3 | solute carrier family 46, member 3 | 0.00393237 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00391722 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00391617 |
| LAMC2 | laminin, gamma 2 | 0.00391569 |
| RGS16 | regulator of G-protein signaling 16 | 0.00391472 |
| TRIP10 | thyroid hormone receptor interactor 10 | 0.00390819 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0039078 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00390655 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00389977 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00389239 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00388794 |
| NOTCH3 | notch 3 | 0.00388765 |
| DUSP10 | dual specificity phosphatase 10 | 0.00388679 |
| IRF9 | interferon regulatory factor 9 | 0.00388463 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00388178 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0150101 |
| PCP4 | Purkinje cell protein 4 | -0.0101008 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0100209 |
| PLK1 | polo-like kinase 1 | -0.00959042 |
| LYZ | lysozyme | -0.00953462 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00900286 |
| LTF | lactotransferrin | -0.0084397 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00804397 |
| OLFM4 | olfactomedin 4 | -0.00729972 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00729094 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00710599 |
| CDC20 | cell division cycle 20 | -0.00685563 |
| PROM1 | prominin 1 | -0.00674235 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00667937 |
| NPTX2 | neuronal pentraxin II | -0.00664415 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00650456 |
| NID1 | nidogen 1 | -0.00648762 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00630957 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00621453 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00619755 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00619441 |
| LY75 | lymphocyte antigen 75 | -0.00613767 |
| OLFM1 | olfactomedin 1 | -0.00611409 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0060854 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00607898 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00592098 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00589609 |
| FABP1 | fatty acid binding protein 1, liver | -0.00586522 |
| TOB1 | transducer of ERBB2, 1 | -0.00583383 |
| MLF1 | myeloid leukemia factor 1 | -0.00579369 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00579338 |
| ARG2 | arginase 2 | -0.0057386 |
| PEG3 | paternally expressed 3 | -0.00571887 |
| FHL1 | four and a half LIM domains 1 | -0.00571112 |
| NEK2 | NIMA-related kinase 2 | -0.0056969 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00565035 |
| DACH1 | dachshund family transcription factor 1 | -0.00564077 |
| PLIN2 | perilipin 2 | -0.00563103 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00562568 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00560953 |
| TGFB1 | transforming growth factor, beta 1 | -0.00557681 |
| GPSM2 | G-protein signaling modulator 2 | -0.00556533 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0055628 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00552012 |
| CD52 | CD52 molecule | -0.00548643 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00547329 |
| CHKB | choline kinase beta | -0.0054633 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00540368 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00539697 |
| SDC2 | syndecan 2 | -0.00538957 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00536594 |
| GRAMD1C | GRAM domain containing 1C | -0.0052867 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00527644 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00527067 |
| NELL2 | NEL-like 2 (chicken) | -0.00526787 |
| ORC1 | origin recognition complex, subunit 1 | -0.00525791 |
| PAX5 | paired box 5 | -0.00523251 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00521204 |
| NDC80 | NDC80 kinetochore complex component | -0.00519998 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00517445 |
| SRGN | serglycin | -0.00516806 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00516786 |
| FBXO5 | F-box protein 5 | -0.00515141 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00512247 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00510418 |
| CAMP | cathelicidin antimicrobial peptide | -0.00509852 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00508532 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00506258 |
| COMMD8 | COMM domain containing 8 | -0.00504342 |
| FOXM1 | forkhead box M1 | -0.00502671 |
| RTN2 | reticulon 2 | -0.00500331 |
| CEP57 | centrosomal protein 57kDa | -0.0050028 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00497736 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00496724 |
| STXBP2 | syntaxin binding protein 2 | -0.0049532 |
| ZNF226 | zinc finger protein 226 | -0.00494169 |
| MANSC1 | MANSC domain containing 1 | -0.00492794 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00492712 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00491469 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00490939 |
| PIMREG | PICALM interacting mitotic regulator | -0.00490737 |
| HHEX | hematopoietically expressed homeobox | -0.00490433 |
| SNX7 | sorting nexin 7 | -0.00489686 |
| NFIB | nuclear factor I/B | -0.00489529 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00488984 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00488724 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00487624 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00486861 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00485106 |
| MT1H | metallothionein 1H | -0.00482681 |
| GUCY2C | guanylate cyclase 2C | -0.00482319 |
| CYRIA | CYFIP related Rac1 interactor A | -0.00480167 |
| CLC | Charcot-Leyden crystal galectin | -0.00478163 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00476451 |
| DES | desmin | -0.00476098 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00473128 |
| FBXO21 | F-box protein 21 | -0.00472343 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.00472 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00471865 |
| SVIL | supervillin | -0.00471349 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.0046967 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00468368 |
| PRAME | preferentially expressed antigen in melanoma | -0.00467615 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.00466723 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00465652 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00465634 |
| CCNB2 | cyclin B2 | -0.00465145 |
| HRASLS | HRAS-like suppressor | -0.00464498 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00464116 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.0046295 |
| EXOSC4 | exosome component 4 | -0.00462236 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00461177 |
| CYTL1 | cytokine-like 1 | -0.00457546 |
| INSIG1 | insulin induced gene 1 | -0.00457329 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00456085 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.00455988 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00455292 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00455149 |
| STK10 | serine/threonine kinase 10 | -0.00454496 |
| AHSG | alpha-2-HS-glycoprotein | -0.00453951 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.0045268 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00451969 |
| STAP2 | signal transducing adaptor family member 2 | -0.00450463 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00450165 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.0045005 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.00447513 |
| PRKCA | protein kinase C, alpha | -0.00447507 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00446611 |
| MB | myoglobin | -0.0044443 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00444286 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00442725 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00440805 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00440227 |
| CYTIP | cytohesin 1 interacting protein | -0.00439322 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.00436753 |
| THEMIS2 | thymocyte selection associated family member 2 | -0.00435751 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.00435558 |
| CCNE2 | cyclin E2 | -0.00435244 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.00430972 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00430337 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00427999 |
| NANS | N-acetylneuraminic acid synthase | -0.00427827 |
| AURKB | aurora kinase B | -0.00426231 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0042568 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.00425256 |
| PHF20 | PHD finger protein 20 | -0.00425165 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00424987 |
| TSPAN13 | tetraspanin 13 | -0.0042284 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.00422541 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.00421666 |
| AXIN1 | axin 1 | -0.00420997 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00420615 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00419882 |
| CFP | complement factor properdin | -0.00419202 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00418236 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00417971 |
| EMC9 | ER membrane protein complex subunit 9 | -0.00417585 |
| PLN | phospholamban | -0.00414925 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00413987 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00413468 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.00413338 |
| IL33 | interleukin 33 | -0.004127 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00412053 |
| DUSP9 | dual specificity phosphatase 9 | -0.00411601 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00411036 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00410634 |
| PF4 | platelet factor 4 | -0.00409984 |
| METRN | meteorin, glial cell differentiation regulator | -0.00408839 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00407991 |
| MSH2 | mutS homolog 2 | -0.0040797 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00407109 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00406533 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00406222 |
| CRYM | crystallin, mu | -0.00405478 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00405299 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00403069 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00402568 |
| OIP5 | Opa interacting protein 5 | -0.00402155 |
| RTN1 | reticulon 1 | -0.0040215 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0040172 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00401473 |
| AGBL5 | ATP/GTP binding protein-like 5 | -0.00400693 |
| KRT23 | keratin 23, type I | -0.00400634 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00400015 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00398884 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00397342 |
| NFASC | neurofascin | -0.0039681 |
| H1-10 | H1.10 linker histone | -0.00396439 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00395276 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00395085 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | -0.00394026 |
| CALML5 | calmodulin-like 5 | -0.00393991 |
| IL27RA | interleukin 27 receptor, alpha | -0.0039396 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00393912 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.00393856 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00392005 |
| PDE10A | phosphodiesterase 10A | -0.00391877 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00390857 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -0.0039083 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00389348 |
| PON3 | paraoxonase 3 | -0.00388896 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00388272 |
| PRR7 | proline rich 7 (synaptic) | -0.00387235 |
| CERK | ceramide kinase | -0.00387136 |
| GLB1 | galactosidase, beta 1 | -0.00386994 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00386904 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00386749 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0038628 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00386151 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00385831 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00385809 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00385486 |
| RAPSN | receptor-associated protein of the synapse | -0.00385334 |
| ABHD10 | abhydrolase domain containing 10 | -0.0038532 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00384504 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00384147 |
| RRM2 | ribonucleotide reductase M2 | -0.00384132 |
| PAH | phenylalanine hydroxylase | -0.00384049 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00383734 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00383098 |
| ANO3 | anoctamin 3 | -0.00382442 |
| KLHDC2 | kelch domain containing 2 | -0.00382378 |
| FBXO11 | F-box protein 11 | -0.00382334 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.0038206 |
| CCNG1 | cyclin G1 | -0.00381921 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00381655 |
| TMEM39B | transmembrane protein 39B | -0.00381494 |
| CLDN3 | claudin 3 | -0.00381135 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.00381025 |
| STMN1 | stathmin 1 | -0.00380586 |
| LBR | lamin B receptor | -0.0038024 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00380097 |
| FST | follistatin | -0.00379654 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00378929 |
| USP1 | ubiquitin specific peptidase 1 | -0.00378208 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.003778 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | -0.00377114 |
| ANXA6 | annexin A6 | -0.00376234 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00375696 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00375281 |
| LEPR | leptin receptor | -0.00375256 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00375144 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00374561 |
| CHMP6 | charged multivesicular body protein 6 | -0.00374447 |
| TXNIP | thioredoxin interacting protein | -0.0037346 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00371957 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00371748 |
| HYOU1 | hypoxia up-regulated 1 | -0.00371724 |
| TK1 | thymidine kinase 1, soluble | -0.00371233 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00370941 |
