| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | potassium channel, voltage gated KQT-like subfamily Q, member 2|The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3785) |
| External Link | https://ncbi.nlm.nih.gov/gene/3785 |
| Similar Terms | |
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499 genes differentially expressed following the KCNQ2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0145924 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.0109497 |
| CA12 | carbonic anhydrase XII | 0.0105534 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.0102543 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.0102374 |
| FOXG1 | forkhead box G1 | 0.00991342 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00964923 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00955733 |
| ADD3 | adducin 3 (gamma) | 0.00943065 |
| PLK1 | polo-like kinase 1 | 0.00919177 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00918116 |
| KLK5 | kallikrein-related peptidase 5 | 0.00913279 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00898054 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00897014 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00891614 |
| TYRP1 | tyrosinase-related protein 1 | 0.00884616 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00877289 |
| HTRA1 | HtrA serine peptidase 1 | 0.00873995 |
| CHPT1 | choline phosphotransferase 1 | 0.00856054 |
| RNASET2 | ribonuclease T2 | 0.00853381 |
| MT1G | metallothionein 1G | 0.00839731 |
| ZNF395 | zinc finger protein 395 | 0.00838976 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00836026 |
| CLCA1 | chloride channel accessory 1 | 0.00817721 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00805716 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00804869 |
| FBXO11 | F-box protein 11 | 0.00789998 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00786421 |
| ANXA4 | annexin A4 | 0.00785323 |
| HAL | histidine ammonia-lyase | 0.0078077 |
| ATP9A | ATPase, class II, type 9A | 0.00770413 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00766085 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00764232 |
| ADM | adrenomedullin | 0.00763498 |
| AOC1 | amine oxidase, copper containing 1 | 0.00761386 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00758112 |
| PEG10 | paternally expressed 10 | 0.00751607 |
| LAGE3 | L antigen family, member 3 | 0.00748305 |
| STK39 | serine threonine kinase 39 | 0.00747211 |
| CAPNS1 | calpain, small subunit 1 | 0.0074584 |
| CLDN8 | claudin 8 | 0.0074161 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00740253 |
| DAXX | death-domain associated protein | 0.00732039 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00729451 |
| PRAME | preferentially expressed antigen in melanoma | 0.00729188 |
| GRAMD2B | GRAM domain containing 2B | 0.00727375 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00722915 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00722809 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00720693 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00720603 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00720531 |
| PITX3 | paired-like homeodomain 3 | 0.00718766 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00715182 |
| FCGBP | Fc fragment of IgG binding protein | 0.00714105 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00713229 |
| SHTN1 | shootin 1 | 0.00708788 |
| RHOC | ras homolog family member C | 0.00708787 |
| FAM162A | family with sequence similarity 162, member A | 0.00705951 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00704502 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00703385 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00702253 |
| ERGIC3 | ERGIC and golgi 3 | 0.00699052 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00698952 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00697154 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00689516 |
| ZG16 | zymogen granule protein 16 | 0.00688257 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00687883 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00686925 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00680913 |
| MT1H | metallothionein 1H | 0.00677596 |
| H1-10 | H1.10 linker histone | 0.00676187 |
| VNN1 | vanin 1 | 0.00675779 |
| MT1F | metallothionein 1F | 0.00672935 |
| METTL7A | methyltransferase like 7A | 0.00672439 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00672006 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00670729 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.00666449 |
| PLPP3 | phospholipid phosphatase 3 | 0.00663576 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00663306 |
| AK4 | adenylate kinase 4 | 0.00662187 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00661015 |
| SELENOW | selenoprotein W | 0.00660653 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00654618 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00653739 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00651436 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0064998 |
| LOXL2 | lysyl oxidase-like 2 | 0.00649161 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00647736 |
| NRN1 | neuritin 1 | 0.00646947 |
| CLTB | clathrin, light chain B | 0.0064624 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00646147 |
| TSC22D1 | TSC22 domain family, member 1 | 0.006414 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00641209 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00640434 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.00639458 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00637043 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00633592 |
| FABP1 | fatty acid binding protein 1, liver | 0.00632212 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00628258 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00628031 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00627245 |
| CAPN3 | calpain 3, (p94) | 0.0062344 |
| DEFB1 | defensin, beta 1 | 0.00619445 |
| EFHD1 | EF-hand domain family, member D1 | 0.00618236 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00616102 |
| CALML5 | calmodulin-like 5 | 0.00615858 |
| HOXC10 | homeobox C10 | 0.00615806 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00615659 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00614152 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00613442 |
| PRSS8 | protease, serine, 8 | 0.00612994 |
| IFI44L | interferon-induced protein 44-like | 0.00612366 |
| LOR | loricrin | 0.00612095 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00611422 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00609687 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00607623 |
| HNMT | histamine N-methyltransferase | 0.00605888 |
| MT1X | metallothionein 1X | 0.00605755 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00605071 |
| SP110 | SP110 nuclear body protein | 0.00603409 |
| JUP | junction plakoglobin | 0.00602262 |
| CALML3 | calmodulin-like 3 | 0.00598623 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.0059854 |
| DSG1 | desmoglein 1 | 0.00597298 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00596984 |
| LEFTY1 | left-right determination factor 1 | 0.00596435 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00595722 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00594855 |
| ZNF91 | zinc finger protein 91 | 0.00594584 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00594469 |
| PIGR | polymeric immunoglobulin receptor | 0.00593632 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00593157 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00593099 |
| GTF3A | general transcription factor IIIA | 0.00585429 |
| OXTR | oxytocin receptor | 0.00583436 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0058308 |
| IQCG | IQ motif containing G | 0.00582552 |
| MT2A | metallothionein 2A | 0.00581573 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00581455 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00581335 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0058126 |
| ARG1 | arginase 1 | 0.00580957 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00579641 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00577203 |
| PFKP | phosphofructokinase, platelet | 0.00574574 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00571669 |
| MT1E | metallothionein 1E | 0.0057051 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00570094 |
| EMX2 | empty spiracles homeobox 2 | 0.00570062 |
| DSC1 | desmocollin 1 | 0.00567996 |
| WASHC4 | WASH complex subunit 4 | 0.0056717 |
| MRTFB | myocardin related transcription factor B | 0.00564125 |
| IFI35 | interferon-induced protein 35 | 0.00564096 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00563155 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00563044 |
| TMEM59 | transmembrane protein 59 | 0.0056245 |
| EIF2D | eukaryotic translation initiation factor 2D | 0.00561553 |
| MVP | major vault protein | 0.00560813 |
| LY96 | lymphocyte antigen 96 | 0.00560683 |
| CLCA2 | chloride channel accessory 2 | 0.00558294 |
| SELE | selectin E | 0.00556389 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00555841 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.00555747 |
| S100A7 | S100 calcium binding protein A7 | 0.0055455 |
| PTHLH | parathyroid hormone-like hormone | 0.00548191 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00548154 |
| COL2A1 | collagen, type II, alpha 1 | 0.00547687 |
| BAX | BCL2-associated X protein | 0.00547125 |
| CDH13 | cadherin 13 | 0.00547007 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00545854 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00545672 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00545224 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00543108 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00542911 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00542684 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00541807 |
| MYOF | myoferlin | 0.00539341 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00538868 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00538743 |
| KIFAP3 | kinesin-associated protein 3 | 0.00538529 |
| YIPF6 | Yip1 domain family, member 6 | 0.0053818 |
| WISP3 | WNT1 inducible signaling pathway protein 3 | 0.00537732 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0053754 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00536662 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00535894 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00535594 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00533705 |
| TXLNA | taxilin alpha | 0.0053347 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00533454 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00530082 |
| FABP7 | fatty acid binding protein 7, brain | 0.00529222 |
| KRT1 | keratin 1, type II | 0.00528098 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0052765 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00525199 |
| EFNA1 | ephrin-A1 | 0.00524536 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00523697 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | 0.00523628 |
| TXNIP | thioredoxin interacting protein | 0.0052327 |
| MYBPC1 | myosin binding protein C, slow type | 0.00523194 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00522537 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00522048 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00521949 |
| OPN3 | opsin 3 | 0.00521526 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.00521071 |
| KRT20 | keratin 20, type I | 0.00521062 |
| DNMBP | dynamin binding protein | 0.00520188 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.00520033 |
| LRRC31 | leucine rich repeat containing 31 | 0.00519819 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00517855 |
| RPS5 | ribosomal protein S5 | 0.00517632 |
| OXLD1 | oxidoreductase-like domain containing 1 | 0.00517156 |
| CLDN10 | claudin 10 | 0.00517099 |
| LYRM4 | LYR motif containing 4 | 0.00517044 |
| SIRT5 | sirtuin 5 | 0.00516931 |
| KRT81 | keratin 81, type II | 0.00516746 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00516175 |
| COMT | catechol-O-methyltransferase | 0.00515617 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00512407 |
| PMP2 | peripheral myelin protein 2 | 0.00511729 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.00511538 |
| RAB29 | RAB29, member RAS oncogene family | 0.00510925 |
| TRIM22 | tripartite motif containing 22 | 0.00510726 |
| MCTS1 | malignant T cell amplified sequence 1 | 0.00510368 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00509813 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.00509811 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00509558 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00508956 |
| CAST | calpastatin | 0.00506644 |
| GPM6A | glycoprotein M6A | 0.00506439 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.00504059 |
| HOXB7 | homeobox B7 | 0.00503948 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | 0.00503425 |
| STAP2 | signal transducing adaptor family member 2 | 0.00503132 |
| AUTS2 | autism susceptibility candidate 2 | 0.00500933 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00500929 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00500677 |
| KRT14 | keratin 14, type I | 0.00500458 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00500294 |
| SPRR1B | small proline-rich protein 1B | 0.00498625 |
| PRKCQ | protein kinase C, theta | 0.00495357 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00493967 |
| REEP5 | receptor accessory protein 5 | 0.00493038 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00492883 |
| CYB5R1 | cytochrome b5 reductase 1 | 0.00492207 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00491353 |
| TCTN3 | tectonic family member 3 | 0.00489999 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00489352 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00489227 |
| LRRC19 | leucine rich repeat containing 19 | 0.00487878 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00486903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | -0.0165871 |
| G0S2 | G0/G1 switch 2 | -0.0142534 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0125171 |
| PCP4 | Purkinje cell protein 4 | -0.0122733 |
| XPO7 | exportin 7 | -0.0120356 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.0112347 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0109469 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0108062 |
| S100A4 | S100 calcium binding protein A4 | -0.0107597 |
| LTF | lactotransferrin | -0.0106335 |
| NELL2 | NEL-like 2 (chicken) | -0.0104426 |
| ASPN | asporin | -0.0101354 |
| FBLN1 | fibulin 1 | -0.00998216 |
| MXRA5 | matrix-remodelling associated 5 | -0.00966947 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00963197 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00962656 |
| METRN | meteorin, glial cell differentiation regulator | -0.00962599 |
| AEBP1 | AE binding protein 1 | -0.00957616 |
| DES | desmin | -0.00951693 |
| GAS1 | growth arrest-specific 1 | -0.00945415 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00934542 |
| KRT19 | keratin 19, type I | -0.00933562 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00920836 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00903251 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00899834 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00875519 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00874371 |
| CCNA2 | cyclin A2 | -0.00873471 |
| ASS1 | argininosuccinate synthase 1 | -0.00866755 |
| INHBA | inhibin, beta A | -0.00861853 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00860508 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00852949 |
| CHGB | chromogranin B | -0.00848912 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00844791 |
| MAGEA3 | melanoma antigen family A3 | -0.00843715 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00841079 |
| PRDX2 | peroxiredoxin 2 | -0.00839876 |
| PGC | progastricsin (pepsinogen C) | -0.0083905 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00827929 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00826967 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00823736 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0081289 |
| PTN | pleiotrophin | -0.00811602 |
| FLNC | filamin C, gamma | -0.0080736 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00805775 |
| SELENBP1 | selenium binding protein 1 | -0.00804452 |
| FEN1 | flap structure-specific endonuclease 1 | -0.00799012 |
| KRT7 | keratin 7, type II | -0.00793473 |
| MFAP4 | microfibrillar-associated protein 4 | -0.0078623 |
| CES1 | carboxylesterase 1 | -0.00779294 |
| S100A8 | S100 calcium binding protein A8 | -0.00767361 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00763981 |
| GLUL | glutamate-ammonia ligase | -0.00762086 |
| CALCA | calcitonin-related polypeptide alpha | -0.00760042 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00758976 |
| AOC3 | amine oxidase, copper containing 3 | -0.00758216 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00756643 |
| OAT | ornithine aminotransferase | -0.00756381 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00755787 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00754891 |
| PCNA | proliferating cell nuclear antigen | -0.00754621 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00753429 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00751682 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00746912 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00743178 |
| BGN | biglycan | -0.00743142 |
| FHL1 | four and a half LIM domains 1 | -0.00742418 |
| CFB | complement factor B | -0.00742197 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00740793 |
| MEIS1 | Meis homeobox 1 | -0.00736946 |
| ANOS1 | anosmin 1 | -0.00734237 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00728531 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00727813 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00726171 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00718959 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0071569 |
| FLNA | filamin A, alpha | -0.00714746 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00712856 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00712428 |
| BCHE | butyrylcholinesterase | -0.00711894 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00710063 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00706015 |
| MEIS2 | Meis homeobox 2 | -0.0069777 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00695413 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00695384 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.00690528 |
| SMAD7 | SMAD family member 7 | -0.00687308 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00686972 |
| APOC1 | apolipoprotein C-I | -0.00686564 |
| REG1A | regenerating islet-derived 1 alpha | -0.00685218 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00685009 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00680279 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00678178 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00677763 |
| IRS1 | insulin receptor substrate 1 | -0.00677011 |
| PRNP | prion protein | -0.0067378 |
| FGF9 | fibroblast growth factor 9 | -0.00666912 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00657918 |
| TYMS | thymidylate synthetase | -0.0065408 |
| PCLAF | PCNA clamp associated factor | -0.00651373 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00648882 |
| ZNF423 | zinc finger protein 423 | -0.00648614 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00647839 |
| PSCA | prostate stem cell antigen | -0.00644753 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00644479 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00643206 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00642436 |
| NDNF | neuron-derived neurotrophic factor | -0.00641094 |
| STK10 | serine/threonine kinase 10 | -0.00640858 |
| ASPH | aspartate beta-hydroxylase | -0.0064053 |
| TLN1 | talin 1 | -0.00634176 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00632849 |
| TGM2 | transglutaminase 2 | -0.00632426 |
| LOXL1 | lysyl oxidase-like 1 | -0.00631397 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | -0.00629386 |
| PLIN1 | perilipin 1 | -0.00626236 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0062613 |
| PGD | phosphogluconate dehydrogenase | -0.00623489 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00620904 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00620411 |
| CHRDL1 | chordin-like 1 | -0.00619553 |
| LUM | lumican | -0.00617371 |
| BAG2 | BCL2-associated athanogene 2 | -0.00617291 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00615703 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.00615575 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00615308 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00612715 |
| MARCO | macrophage receptor with collagenous structure | -0.00611704 |
| PLN | phospholamban | -0.00611524 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00611338 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 | -0.00611107 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00610439 |
| SULF1 | sulfatase 1 | -0.00610405 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.0060432 |
| JMJD1C | jumonji domain containing 1C | -0.00602901 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00602883 |
| RAPSN | receptor-associated protein of the synapse | -0.00602058 |
| CACYBP | calcyclin binding protein | -0.00601261 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00600812 |
| PNN | pinin, desmosome associated protein | -0.00599811 |
| MCOLN1 | mucolipin 1 | -0.00599554 |
| LCN2 | lipocalin 2 | -0.00599017 |
| CNTN1 | contactin 1 | -0.005989 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00598522 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00598375 |
| C3 | complement component 3 | -0.00597912 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00595266 |
| TCERG1 | transcription elongation regulator 1 | -0.00594237 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00592548 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00591704 |
| C7 | complement component 7 | -0.00591447 |
| SCG5 | secretogranin V | -0.00587811 |
| FILIP1L | filamin A interacting protein 1-like | -0.00586887 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00586068 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0058591 |
| MMP1 | matrix metallopeptidase 1 | -0.00585449 |
| ANGPT1 | angiopoietin 1 | -0.00585343 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | -0.00583707 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00582348 |
| PLAU | plasminogen activator, urokinase | -0.00582322 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00582247 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00580803 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.00580427 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.005785 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00577867 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00576705 |
| SFTPB | surfactant protein B | -0.00575667 |
| TSPYL5 | TSPY-like 5 | -0.00575518 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | -0.0057393 |
| FUS | FUS RNA binding protein | -0.00573818 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00573056 |
| RCOR1 | REST corepressor 1 | -0.00572457 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00571826 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00569523 |
| SYNM | synemin, intermediate filament protein | -0.00568217 |
| RBM25 | RNA binding motif protein 25 | -0.00567086 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00566305 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0056513 |
| CCND2 | cyclin D2 | -0.00564931 |
| ZNF532 | zinc finger protein 532 | -0.00564795 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00562293 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00562005 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00558441 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00557345 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00553743 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.00552635 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.00551693 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00550062 |
| RELN | reelin | -0.00549971 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00549711 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | -0.00548553 |
| RESF1 | retroelement silencing factor 1 | -0.00546593 |
| H2AZ1 | H2A.Z variant histone 1 | -0.00544752 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00544257 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00543854 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00543561 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00543389 |
| LMNB2 | lamin B2 | -0.00542668 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00541712 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00538198 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00535467 |
| TNS1 | tensin 1 | -0.00532401 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.0053214 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.00531942 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | -0.00531582 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00527346 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00526787 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0052658 |
| IRS2 | insulin receptor substrate 2 | -0.00526263 |
| DUSP5 | dual specificity phosphatase 5 | -0.00525676 |
| PLAT | plasminogen activator, tissue | -0.00522989 |
| MFAP5 | microfibrillar associated protein 5 | -0.00522931 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00521765 |
| STXBP2 | syntaxin binding protein 2 | -0.00521314 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00520857 |
| NIT1 | nitrilase 1 | -0.00520464 |
| RRM2 | ribonucleotide reductase M2 | -0.00519561 |
| LPIN2 | lipin 2 | -0.00519557 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00518711 |
| RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | -0.00518199 |
| ZNF331 | zinc finger protein 331 | -0.00516676 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00516139 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00514978 |
| RTN3 | reticulon 3 | -0.00514897 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00513922 |
| JMJD6 | jumonji domain containing 6 | -0.0051348 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00513024 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00511835 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00509419 |
| TAGLN | transgelin | -0.00509297 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00508865 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00507852 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00506668 |
| ELOC | elongin C | -0.00505548 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00505067 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | -0.0050246 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -0.00501657 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00500812 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00500655 |
| DUSP10 | dual specificity phosphatase 10 | -0.00500179 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00500098 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | -0.00499707 |
| PODXL | podocalyxin-like | -0.00499131 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00498332 |
| DPT | dermatopontin | -0.00494614 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0049411 |
| NPTN | neuroplastin | -0.00493327 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00493275 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -0.00493138 |
