KDM5B Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description lysine (K)-specific demethylase 5B| (NCBI Entrez Gene Database, 10765)
External Link https://ncbi.nlm.nih.gov/gene/10765
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Genes

500 genes differentially expressed following the KDM5B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.00925895
S100P S100 calcium binding protein P 0.00890916
LIMCH1 LIM and calponin homology domains 1 0.00862787
AQP3 aquaporin 3 (Gill blood group) 0.00842889
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00828663
NEBL nebulette 0.00822908
CXADR coxsackie virus and adenovirus receptor 0.00814677
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00785004
BMP2 bone morphogenetic protein 2 0.00763157
ANOS1 anosmin 1 0.00752764
HSPB8 heat shock 22kDa protein 8 0.00733439
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00722115
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00718698
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.00688797
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00664383
ABLIM1 actin binding LIM protein 1 0.00653976
RHOB ras homolog family member B 0.00649567
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0064583
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00638197
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00634912
C8ORF4 chromosome 8 open reading frame 4 0.00629956
ADIRF adipogenesis regulatory factor 0.00618908
NRN1 neuritin 1 0.00611968
FABP4 fatty acid binding protein 4, adipocyte 0.00599504
DENND1B DENN/MADD domain containing 1B 0.00595868
KRT7 keratin 7, type II 0.00593853
TNNC1 troponin C type 1 (slow) 0.00593839
EFNA1 ephrin-A1 0.0059328
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00589691
CALCRL calcitonin receptor-like 0.00586401
MT1M metallothionein 1M 0.0057985
HNMT histamine N-methyltransferase 0.00577663
ASCL1 achaete-scute family bHLH transcription factor 1 0.00573969
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0057266
GADD45B growth arrest and DNA-damage-inducible, beta 0.0056649
ELL2 elongation factor, RNA polymerase II, 2 0.00563988
TTN titin 0.005633
NDNF neuron-derived neurotrophic factor 0.00562406
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00562359
FAM107A family with sequence similarity 107, member A 0.00561421
TSPAN7 tetraspanin 7 0.00559696
ZBTB16 zinc finger and BTB domain containing 16 0.00559024
MALL mal, T-cell differentiation protein-like 0.00558166
FGF13 fibroblast growth factor 13 0.00557291
TSPAN8 tetraspanin 8 0.00553547
CRYAB crystallin, alpha B 0.00552227
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00550571
SASH1 SAM and SH3 domain containing 1 0.00550106
GPM6B glycoprotein M6B 0.00547894
OPHN1 oligophrenin 1 0.00547877
PTHLH parathyroid hormone-like hormone 0.00542731
KLF4 Kruppel-like factor 4 (gut) 0.00538415
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0053418
C1QB complement component 1, q subcomponent, B chain 0.00533252
CXCL14 chemokine (C-X-C motif) ligand 14 0.00533067
SATB2 SATB homeobox 2 0.00531844
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00529113
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00528737
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.0052518
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00520264
GATA3 GATA binding protein 3 0.00518818
LPP LIM domain containing preferred translocation partner in lipoma 0.00515116
DHCR24 24-dehydrocholesterol reductase 0.00512675
SFTPA2 surfactant protein A2 0.00510826
CXCL9 chemokine (C-X-C motif) ligand 9 0.00507288
AUTS2 autism susceptibility candidate 2 0.00504081
ALCAM activated leukocyte cell adhesion molecule 0.00503522
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00500339
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00489924
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00486805
FABP7 fatty acid binding protein 7, brain 0.00486585
PSAT1 phosphoserine aminotransferase 1 0.00485568
COL4A6 collagen, type IV, alpha 6 0.00484922
TENT5A terminal nucleotidyltransferase 5A 0.00484281
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00482185
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.00477754
SLPI secretory leukocyte peptidase inhibitor 0.00477115
CHRDL1 chordin-like 1 0.00474009
C1QA complement component 1, q subcomponent, A chain 0.00473994
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00473942
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00472526
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00470072
LAMP3 lysosomal-associated membrane protein 3 0.00467182
SFTPD surfactant protein D 0.00466297
KLF6 Kruppel-like factor 6 0.00462551
EPAS1 endothelial PAS domain protein 1 0.00460734
QKI QKI, KH domain containing, RNA binding 0.00460026
MT1E metallothionein 1E 0.00458717
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00451899
LMCD1 LIM and cysteine-rich domains 1 0.00451592
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00450438
DST dystonin 0.00448265
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00448094
CNTN1 contactin 1 0.0044788
NKX2-1 NK2 homeobox 1 0.00447068
SYBU syntabulin (syntaxin-interacting) 0.00446133
TACSTD2 tumor-associated calcium signal transducer 2 0.00445933
MCL1 myeloid cell leukemia 1 0.00443661
AIM2 absent in melanoma 2 0.00442667
CCL14 chemokine (C-C motif) ligand 14 0.00442342
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.00441039
EMP2 epithelial membrane protein 2 0.00439305
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00438193
TACC2 transforming, acidic coiled-coil containing protein 2 0.00438128
MYBPC1 myosin binding protein C, slow type 0.00438071
AGTR1 angiotensin II receptor, type 1 0.00437865
TIMP4 TIMP metallopeptidase inhibitor 4 0.00437564
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00436574
MGLL monoglyceride lipase 0.00436347
MGP matrix Gla protein 0.00434115
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00430624
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0043054
IDE insulin-degrading enzyme 0.00429881
PON3 paraoxonase 3 0.00429602
SCGB2A2 secretoglobin, family 2A, member 2 0.00429569
SFTPB surfactant protein B 0.00428479
RND3 Rho family GTPase 3 0.00428007
GEM GTP binding protein overexpressed in skeletal muscle 0.004264
PNMA2 paraneoplastic Ma antigen 2 0.00425098
UNC13B unc-13 homolog B (C. elegans) 0.00425072
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00425035
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.0042486
THBD thrombomodulin 0.00424007
FERMT2 fermitin family member 2 0.00423932
GPX3 glutathione peroxidase 3 0.00422888
CAST calpastatin 0.00421436
CSNK1E casein kinase 1, epsilon 0.00420535
TMEM47 transmembrane protein 47 0.00418668
MSX1 msh homeobox 1 0.00418169
TMCC1 transmembrane and coiled-coil domain family 1 0.00416318
C10ORF10 chromosome 10 open reading frame 10 0.00416089
WSB1 WD repeat and SOCS box containing 1 0.00415949
STOM stomatin 0.00415904
TSPAN13 tetraspanin 13 0.00415888
TYMP thymidine phosphorylase 0.00414705
RIPK2 receptor-interacting serine-threonine kinase 2 0.00412834
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00410939
CDA cytidine deaminase 0.00409821
CCL4 chemokine (C-C motif) ligand 4 0.00408308
ITM2A integral membrane protein 2A 0.00407501
LMAN1 lectin, mannose-binding, 1 0.00407016
ELOVL5 ELOVL fatty acid elongase 5 0.00406367
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00405953
RAB21 RAB21, member RAS oncogene family 0.00404717
AQP1 aquaporin 1 (Colton blood group) 0.00403978
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00401446
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00399878
PDE4B phosphodiesterase 4B, cAMP-specific 0.00398084
CPE carboxypeptidase E 0.00397975
PPAP2A phosphatidic acid phosphatase type 2A 0.00397248
SLC38A2 solute carrier family 38, member 2 0.00396878
RNF167 ring finger protein 167 0.00395232
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00394889
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00394672
VAV3 vav 3 guanine nucleotide exchange factor 0.00394614
OGA O-GlcNAcase 0.00393453
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00393439
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00392936
DEFB4A defensin, beta 4A 0.00392524
ITGA6 integrin, alpha 6 0.00392351
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00389764
TMPRSS2 transmembrane protease, serine 2 0.00388125
HIST1H2AC histone cluster 1, H2ac 0.00386622
RETREG1 reticulophagy regulator 1 0.0038585
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00384991
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00384905
NLGN4X neuroligin 4, X-linked 0.0038381
MAST4 microtubule associated serine/threonine kinase family member 4 0.00383394
FHL1 four and a half LIM domains 1 0.00383271
LAMB3 laminin, beta 3 0.0038295
ICAM1 intercellular adhesion molecule 1 0.00378337
DLX5 distal-less homeobox 5 0.00378172
AKAP8 A kinase (PRKA) anchor protein 8 0.00377614
TOX3 TOX high mobility group box family member 3 0.00375631
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00374834
ZEB1 zinc finger E-box binding homeobox 1 0.00374826
ZFAND5 zinc finger, AN1-type domain 5 0.00374415
EXOC5 exocyst complex component 5 0.00374192
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.003739
PMP2 peripheral myelin protein 2 0.00373586
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00373581
CELF2 CUGBP, Elav-like family member 2 0.00373253
GLUL glutamate-ammonia ligase 0.00371677
HOPX HOP homeobox 0.00371427
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00371221
SFTPC surfactant protein C 0.00370893
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0037025
TICAM1 toll-like receptor adaptor molecule 1 0.0036903
ATF3 activating transcription factor 3 0.00366193
LUM lumican 0.00365726
OSMR oncostatin M receptor 0.00365365
ADAM10 ADAM metallopeptidase domain 10 0.00365049
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00364965
NDRG1 N-myc downstream regulated 1 0.00364116
EGR1 early growth response 1 0.00363798
SIK1 salt-inducible kinase 1 0.00362547
HIST1H2BD histone cluster 1, H2bd 0.00361012
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00358554
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.00358216
C4BPA complement component 4 binding protein, alpha 0.00357938
VIM vimentin 0.00357524
JAM2 junctional adhesion molecule 2 0.00356995
PIP prolactin-induced protein 0.00356345
PAWR PRKC, apoptosis, WT1, regulator 0.0035274
CTSC cathepsin C 0.00351946
SCEL sciellin 0.00351897
SYT17 synaptotagmin XVII 0.00351174
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00350659
ANXA3 annexin A3 0.00350614
MAP2 microtubule-associated protein 2 0.00349497
RRAGC Ras-related GTP binding C 0.00348908
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00348414
TMEM100 transmembrane protein 100 0.00348378
SETBP1 SET binding protein 1 0.00347662
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00347611
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00347169
OLFML2A olfactomedin-like 2A 0.00346969
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 0.00346945
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.003468
CAV1 caveolin 1, caveolae protein, 22kDa 0.0034655
KCTD20 potassium channel tetramerization domain containing 20 0.00346384
ITGB6 integrin, beta 6 0.00346227
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00346024
MMP10 matrix metallopeptidase 10 0.00345351
GBP2 guanylate binding protein 2, interferon-inducible 0.00345043
DENND3 DENN/MADD domain containing 3 0.00344045
PTGES prostaglandin E synthase 0.00343973
CALML5 calmodulin-like 5 0.00343911
WIF1 WNT inhibitory factor 1 0.00342747
VWA5A von Willebrand factor A domain containing 5A 0.00342158
FAM198B family with sequence similarity 198, member B 0.00341773
EXT1 exostosin glycosyltransferase 1 0.00341757
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00341032
KYNU kynureninase 0.00340886
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00340721
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00339516
MYO1B myosin IB 0.00339505
CLEC2B C-type lectin domain family 2, member B 0.00338026
SORBS2 sorbin and SH3 domain containing 2 0.00337849
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00337353
CLEC3B C-type lectin domain family 3, member B 0.00336822
ANK2 ankyrin 2, neuronal 0.00336172
ICAM2 intercellular adhesion molecule 2 0.0033585
HIST1H2AE histone cluster 1, H2ae 0.00333251
TFPI2 tissue factor pathway inhibitor 2 0.00333231
LYPD3 LY6/PLAUR domain containing 3 0.0033298
EIF5 eukaryotic translation initiation factor 5 0.0033291
FRZB frizzled-related protein 0.00332472
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00331887
WWC2 WW and C2 domain containing 2 0.0033188

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -0.0190649
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00860018
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00819402
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00788576
NUSAP1 nucleolar and spindle associated protein 1 -0.00783426
WT1 Wilms tumor 1 -0.00671094
TYMS thymidylate synthetase -0.00668676
CREG1 cellular repressor of E1A-stimulated genes 1 -0.00624881
EIF5A eukaryotic translation initiation factor 5A -0.00614366
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.0060365
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00598054
OLFM4 olfactomedin 4 -0.00594077
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00590654
MEIS1 Meis homeobox 1 -0.00582808
HOXB2 homeobox B2 -0.00582389
OAT ornithine aminotransferase -0.00565207
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00564137
EPCAM epithelial cell adhesion molecule -0.00543796
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00543147
H2AX H2A.X variant histone -0.00542822
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00532271
SCGB2A1 secretoglobin, family 2A, member 1 -0.00529362
SEC23A Sec23 homolog A (S. cerevisiae) -0.00519391
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.00512817
BASP1 brain abundant, membrane attached signal protein 1 -0.00506417
THAP12 THAP domain containing 12 -0.00504436
MMP1 matrix metallopeptidase 1 -0.0050228
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00500767
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -0.00499439
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00498794
CD9 CD9 molecule -0.00498201
PDLIM4 PDZ and LIM domain 4 -0.00497534
ISYNA1 inositol-3-phosphate synthase 1 -0.00495283
CPB1 carboxypeptidase B1 (tissue) -0.00487672
CCP110 centriolar coiled coil protein 110kDa -0.00486516
PRAME preferentially expressed antigen in melanoma -0.00485473
LYZ lysozyme -0.00481278
ESR1 estrogen receptor 1 -0.00481179
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00478117
HOOK2 hook microtubule-tethering protein 2 -0.00476724
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.0047604
PRDX2 peroxiredoxin 2 -0.00475252
PRPF4 pre-mRNA processing factor 4 -0.0047452
CTSB cathepsin B -0.00473621
DLK1 delta-like 1 homolog (Drosophila) -0.0047296
CPA3 carboxypeptidase A3 (mast cell) -0.00472343
LOXL1 lysyl oxidase-like 1 -0.00470448
COL10A1 collagen, type X, alpha 1 -0.00470168
PRC1 protein regulator of cytokinesis 1 -0.004701
MXRA7 matrix-remodelling associated 7 -0.00468458
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00462548
DMAC2L distal membrane arm assembly component 2 like -0.00461721
F13A1 coagulation factor XIII, A1 polypeptide -0.00457976
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00457413
THBS1 thrombospondin 1 -0.00457048
KRT19 keratin 19, type I -0.00456038
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00453848
FZD2 frizzled class receptor 2 -0.00451977
PCLAF PCNA clamp associated factor -0.00450747
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00450721
SPON1 spondin 1, extracellular matrix protein -0.00449724
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00448001
COMP cartilage oligomeric matrix protein -0.00446863
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.0044654
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00446061
PDGFC platelet derived growth factor C -0.00443819
CCNF cyclin F -0.00442787
CEP170 centrosomal protein 170kDa -0.00442305
DSP desmoplakin -0.00441932
ANPEP alanyl (membrane) aminopeptidase -0.00441502
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00440659
TMEM14B transmembrane protein 14B -0.00439033
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00438297
EFR3A EFR3 homolog A (S. cerevisiae) -0.00436295
REG1A regenerating islet-derived 1 alpha -0.00430188
PLK2 polo-like kinase 2 -0.00429576
NTS neurotensin -0.004287
MDK midkine (neurite growth-promoting factor 2) -0.00426362
SMC1A structural maintenance of chromosomes 1A -0.00425494
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00424646
CPOX coproporphyrinogen oxidase -0.00423109
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00422573
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -0.00420359
FGFR3 fibroblast growth factor receptor 3 -0.00413514
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -0.00410967
RRAGA Ras-related GTP binding A -0.00410593
MAGEA3 melanoma antigen family A3 -0.00409451
MELK maternal embryonic leucine zipper kinase -0.0040937
NMU neuromedin U -0.00407127
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00406575
CLCA1 chloride channel accessory 1 -0.0040546
CCL2 chemokine (C-C motif) ligand 2 -0.00403489
HIST1H2BK histone cluster 1, H2bk -0.00403047
LY6E lymphocyte antigen 6 complex, locus E -0.00402123
PBLD phenazine biosynthesis-like protein domain containing -0.00399806
ATP5ME ATP synthase membrane subunit e -0.00399294
NPTX2 neuronal pentraxin II -0.00398876
PCP4 Purkinje cell protein 4 -0.00398572
PCNA proliferating cell nuclear antigen -0.00397349
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00397069
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00393819
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00393325
TLK2 tousled-like kinase 2 -0.00392164
NID2 nidogen 2 (osteonidogen) -0.00391621
CLDN10 claudin 10 -0.00390783
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.00389674
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00389246
PFN2 profilin 2 -0.00389035
SQOR sulfide quinone oxidoreductase -0.00388582
FEN1 flap structure-specific endonuclease 1 -0.00386393
TSPAN5 tetraspanin 5 -0.00386242
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00386205
PNMA8A PNMA family member 8A -0.00384471
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0038394
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.0038339
TMEM14A transmembrane protein 14A -0.00383056
LEF1 lymphoid enhancer-binding factor 1 -0.00382504
IFITM2 interferon induced transmembrane protein 2 -0.00382194
IL7 interleukin 7 -0.00381923
MAOB monoamine oxidase B -0.00379101
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.00378564
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00377847
CYRIB CYFIP related Rac1 interactor B -0.0037755
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.00377466
SPON2 spondin 2, extracellular matrix protein -0.00377206
RAB13 RAB13, member RAS oncogene family -0.00376009
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -0.00375746
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.0037494
PKM pyruvate kinase, muscle -0.00374042
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00373584
DCT dopachrome tautomerase -0.00372809
MAEA macrophage erythroblast attacher -0.00372174
MMP11 matrix metallopeptidase 11 -0.00369759
MMP9 matrix metallopeptidase 9 -0.00367874
PCCB propionyl CoA carboxylase, beta polypeptide -0.00364403
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.00364176
GDF15 growth differentiation factor 15 -0.00363139
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00362847
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.003628
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.00362542
COL2A1 collagen, type II, alpha 1 -0.00362181
BRCA1 breast cancer 1, early onset -0.00360711
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) -0.00360272
GSTO1 glutathione S-transferase omega 1 -0.0036027
OVGP1 oviductal glycoprotein 1, 120kDa -0.00359905
REG1B regenerating islet-derived 1 beta -0.0035968
LRRC17 leucine rich repeat containing 17 -0.0035857
NPC2 Niemann-Pick disease, type C2 -0.0035765
HMGB2 high mobility group box 2 -0.00357053
MPC2 mitochondrial pyruvate carrier 2 -0.00356213
MPRIP myosin phosphatase Rho interacting protein -0.00355942
MAT2B methionine adenosyltransferase II, beta -0.00355704
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -0.00355556
TSPYL5 TSPY-like 5 -0.00355082
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0035462
CEL carboxyl ester lipase -0.00353636
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -0.00352685
TYRP1 tyrosinase-related protein 1 -0.00351582
CDC20 cell division cycle 20 -0.00350438
RBM38 RNA binding motif protein 38 -0.00350163
TOB1 transducer of ERBB2, 1 -0.00349154
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00349062
NPEPL1 aminopeptidase-like 1 -0.00348581
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00348522
PTTG1 pituitary tumor-transforming 1 -0.00347019
ZNF395 zinc finger protein 395 -0.00346077
PMEL premelanosome protein -0.00345826
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00345336
ZBTB18 zinc finger and BTB domain containing 18 -0.0034425
NEK2 NIMA-related kinase 2 -0.00343871
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.00341714
TRIB2 tribbles pseudokinase 2 -0.00340875
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00340047
SOCS5 suppressor of cytokine signaling 5 -0.00339805
AREG amphiregulin -0.00339496
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.00338862
TSNAX translin-associated factor X -0.00337245
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -0.00336119
LOXL2 lysyl oxidase-like 2 -0.00335931
DDHD2 DDHD domain containing 2 -0.00335811
REG3A regenerating islet-derived 3 alpha -0.00334335
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.00334189
DNAAF2 dynein, axonemal, assembly factor 2 -0.00334011
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -0.00333941
COMMD8 COMM domain containing 8 -0.00333762
ALB albumin -0.00333747
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.0033207
ADGRG2 adhesion G protein-coupled receptor G2 -0.00331905
PLXNC1 plexin C1 -0.00331337
NPM3 nucleophosmin/nucleoplasmin 3 -0.00330566
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00329732
MCM2 minichromosome maintenance complex component 2 -0.0032955
NYNRIN NYN domain and retroviral integrase containing -0.00329314
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -0.00329102
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.00328664
SEPTIN11 septin 11 -0.0032835
RANBP1 RAN binding protein 1 -0.00327484
DEK DEK proto-oncogene -0.00326984
AMD1 adenosylmethionine decarboxylase 1 -0.00326493
GREM1 gremlin 1, DAN family BMP antagonist -0.00326265
FAM111A family with sequence similarity 111, member A -0.00326232
HAUS3 HAUS augmin-like complex, subunit 3 -0.00325932
FOXJ1 forkhead box J1 -0.00325887
KDM4C lysine (K)-specific demethylase 4C -0.00325739
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00325429
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00325426
COL6A1 collagen, type VI, alpha 1 -0.00324676
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -0.00323963
PTK2 protein tyrosine kinase 2 -0.00323038
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -0.00322411
MTCH2 mitochondrial carrier 2 -0.0032231
MARCKSL1 MARCKS-like 1 -0.0032221
NEO1 neogenin 1 -0.00320872
FCMR Fc fragment of IgM receptor -0.00320499
RAB4A RAB4A, member RAS oncogene family -0.00320291
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.00320235
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -0.00319827
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00319625
IFI6 interferon, alpha-inducible protein 6 -0.00319286
SLBP stem-loop binding protein -0.00319284
MACROH2A2 macroH2A.2 histone -0.00319101
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00318442
FANCL Fanconi anemia, complementation group L -0.00318434
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00318151
ADCY1 adenylate cyclase 1 (brain) -0.003179
GSTA1 glutathione S-transferase alpha 1 -0.00317628
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00317075
CERS6 ceramide synthase 6 -0.00316473
SMC4 structural maintenance of chromosomes 4 -0.00316398
CCDC69 coiled-coil domain containing 69 -0.00315577
RNF115 ring finger protein 115 -0.00315222
NPTN neuroplastin -0.00315203
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00315001
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00314403
ANXA4 annexin A4 -0.00313976
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00313971
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00313871
FAS Fas cell surface death receptor -0.00313715
NUTF2 nuclear transport factor 2 -0.00313147
NENF neudesin neurotrophic factor -0.00312875
TMED7 transmembrane emp24 protein transport domain containing 7 -0.00312801
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0031197
CHGA chromogranin A -0.00311442
XYLT1 xylosyltransferase I -0.00311354
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00310838
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00310565
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.00310514
TUBA1A tubulin, alpha 1a -0.00309678
GCG glucagon -0.00309251
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00309145