KDR Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description kinase insert domain receptor|Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 3791)
External Link http://www.ncbi.nlm.nih.gov/gene/3791
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3 substrates of the kinase KDR from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
FLT4 fms-related tyrosine kinase 4
KDR kinase insert domain receptor
PFN1 profilin 1