| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | kelch-like ECH-associated protein 1|This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9817) |
| External Link | https://ncbi.nlm.nih.gov/gene/9817 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the KEAP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0410182 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0230858 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.020837 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0204499 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0199515 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0198843 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0190686 |
| CPE | carboxypeptidase E | 0.0173788 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0169056 |
| RGCC | regulator of cell cycle | 0.0168563 |
| S100P | S100 calcium binding protein P | 0.0163746 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0149532 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.014869 |
| HMOX1 | heme oxygenase 1 | 0.0147841 |
| ASS1 | argininosuccinate synthase 1 | 0.0146449 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0145983 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0145829 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.0144652 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0143424 |
| G0S2 | G0/G1 switch 2 | 0.0141446 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0138758 |
| HHEX | hematopoietically expressed homeobox | 0.0137677 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0136478 |
| PDZD2 | PDZ domain containing 2 | 0.0133489 |
| CLU | clusterin | 0.0126769 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0126317 |
| ANXA3 | annexin A3 | 0.0126047 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0122791 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0121083 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0120505 |
| CAV2 | caveolin 2 | 0.0119609 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0117092 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0114895 |
| PCDH9 | protocadherin 9 | 0.0113251 |
| CNTN1 | contactin 1 | 0.0111314 |
| TMEM100 | transmembrane protein 100 | 0.0111019 |
| MECOM | MDS1 and EVI1 complex locus | 0.0109326 |
| MAP7 | microtubule-associated protein 7 | 0.0108369 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0107981 |
| AUTS2 | autism susceptibility candidate 2 | 0.01075 |
| CTTN | cortactin | 0.0106618 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0106202 |
| GPC3 | glypican 3 | 0.0106043 |
| PGD | phosphogluconate dehydrogenase | 0.0105496 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0104942 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0104157 |
| KYNU | kynureninase | 0.0103079 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0102948 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0102699 |
| CUX1 | cut-like homeobox 1 | 0.0102532 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.0101909 |
| MMP10 | matrix metallopeptidase 10 | 0.0101287 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.0101147 |
| PODXL | podocalyxin-like | 0.00995528 |
| PEG10 | paternally expressed 10 | 0.00991841 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00991552 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00989034 |
| TXNRD1 | thioredoxin reductase 1 | 0.00984887 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00983994 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00977573 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00975647 |
| ITM2A | integral membrane protein 2A | 0.0096969 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00960045 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00948671 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00943985 |
| IRS2 | insulin receptor substrate 2 | 0.00941451 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00941419 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.0093526 |
| LAMB3 | laminin, beta 3 | 0.00931319 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00930529 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0092456 |
| VWF | von Willebrand factor | 0.00915261 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00914419 |
| TPM4 | tropomyosin 4 | 0.00914142 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00910211 |
| ANXA1 | annexin A1 | 0.00908208 |
| PAX5 | paired box 5 | 0.00904843 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00903729 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.0090198 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00900712 |
| STC2 | stanniocalcin 2 | 0.00897516 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00896735 |
| HIRA | histone cell cycle regulator | 0.00895615 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00893709 |
| KIF14 | kinesin family member 14 | 0.00892412 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00891161 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00886908 |
| MUC16 | mucin 16, cell surface associated | 0.00885856 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00879051 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00877411 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00874235 |
| ATF3 | activating transcription factor 3 | 0.00872076 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00869977 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00869159 |
| GNAS | GNAS complex locus | 0.00868298 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0086777 |
| TPD52L1 | tumor protein D52-like 1 | 0.00865461 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00864954 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00864776 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00864149 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00861343 |
| SERTAD2 | SERTA domain containing 2 | 0.00860656 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00860371 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00859626 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00856044 |
| CCDC6 | coiled-coil domain containing 6 | 0.00853391 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | 0.00850677 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00850483 |
| PNN | pinin, desmosome associated protein | 0.00847789 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00847227 |
| SETD5 | SET domain containing 5 | 0.00846113 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.00845921 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00844423 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00842722 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00842647 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00842531 |
| MID1 | midline 1 | 0.00837897 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00836523 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00834981 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00834672 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00833826 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00831647 |
| GAP43 | growth associated protein 43 | 0.00827964 |
| YBX3 | Y box binding protein 3 | 0.00824135 |
| RIOX2 | ribosomal oxygenase 2 | 0.0082385 |
| HP | haptoglobin | 0.00823152 |
| WT1 | Wilms tumor 1 | 0.00821525 |
| SRSF10 | serine/arginine-rich splicing factor 10 | 0.00820633 |
| CA2 | carbonic anhydrase II | 0.0082035 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00817819 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00814882 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00813524 |
| FGG | fibrinogen gamma chain | 0.00813332 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00813218 |
| TRIB3 | tribbles pseudokinase 3 | 0.00812044 |
| WDR19 | WD repeat domain 19 | 0.00807452 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00795091 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00790998 |
| MFAP4 | microfibrillar-associated protein 4 | 0.0078939 |
| MGLL | monoglyceride lipase | 0.00788925 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00787891 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00784448 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.00783548 |
| CD99 | CD99 molecule | 0.00782615 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00780699 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00779025 |
| PBK | PDZ binding kinase | 0.00775447 |
| YAP1 | Yes-associated protein 1 | 0.00774613 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00774501 |
| FOXF2 | forkhead box F2 | 0.0077375 |
| BTG3 | BTG family, member 3 | 0.00769662 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00768881 |
| GPATCH8 | G patch domain containing 8 | 0.00766699 |
| BMP2 | bone morphogenetic protein 2 | 0.00766571 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00765997 |
| C1ORF56 | chromosome 1 open reading frame 56 | 0.00763186 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00759166 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00758407 |
| ABHD3 | abhydrolase domain containing 3 | 0.00758049 |
| MT1M | metallothionein 1M | 0.00757382 |
| CCDC86 | coiled-coil domain containing 86 | 0.00757141 |
| FHL1 | four and a half LIM domains 1 | 0.00756835 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.00755975 |
| ODC1 | ornithine decarboxylase 1 | 0.00755949 |
| PAX6 | paired box 6 | 0.00753469 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00752645 |
| RNF146 | ring finger protein 146 | 0.00752629 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00748555 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00748249 |
| ADCY3 | adenylate cyclase 3 | 0.00746884 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | 0.00745761 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00742991 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00742386 |
| WASF2 | WAS protein family, member 2 | 0.00741399 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00739183 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00737871 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00737168 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00737127 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00736204 |
| FOXO1 | forkhead box O1 | 0.00735378 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00734792 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | 0.0073199 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.00730255 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00730188 |
| SLBP | stem-loop binding protein | 0.00728634 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00728042 |
| KRT17 | keratin 17, type I | 0.00727695 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.00727421 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00727229 |
| ANGPT2 | angiopoietin 2 | 0.00725819 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.00725249 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00724702 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00724545 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00724453 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0072409 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00723827 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00723046 |
| FADS3 | fatty acid desaturase 3 | 0.0072206 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00721844 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00719669 |
| NEFH | neurofilament, heavy polypeptide | 0.00716105 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.00715814 |
| ALB | albumin | 0.00714133 |
| RASA4 | RAS p21 protein activator 4 | 0.00713121 |
| SIK1 | salt-inducible kinase 1 | 0.00712454 |
| SCG5 | secretogranin V | 0.00711443 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00710644 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00709233 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00708816 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00708421 |
| APOC3 | apolipoprotein C-III | 0.00708122 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.00707953 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00707409 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0070676 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00706385 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.00704452 |
| SNX13 | sorting nexin 13 | 0.00703693 |
| CLGN | calmegin | 0.00703635 |
| HECA | headcase homolog (Drosophila) | 0.0070358 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00703231 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00703187 |
| CUL1 | cullin 1 | 0.00702241 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00700706 |
| OLFM1 | olfactomedin 1 | 0.00700446 |
| WASF1 | WAS protein family, member 1 | 0.00700296 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00696557 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00695612 |
| PDAP1 | PDGFA associated protein 1 | 0.00695122 |
| SYCP2 | synaptonemal complex protein 2 | 0.00693197 |
| MCL1 | myeloid cell leukemia 1 | 0.0069095 |
| CDA | cytidine deaminase | 0.00690036 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00688185 |
| CNPY2 | canopy FGF signaling regulator 2 | 0.00685322 |
| GGCX | gamma-glutamyl carboxylase | 0.00683497 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0067936 |
| TCERG1 | transcription elongation regulator 1 | 0.00676181 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00675892 |
| FASTKD3 | FAST kinase domains 3 | 0.00674932 |
| ACKR3 | atypical chemokine receptor 3 | 0.00673976 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.00673872 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00673574 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00672299 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00672173 |
| CSTA | cystatin A (stefin A) | 0.00671754 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0067164 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.00671585 |
| PLAGL2 | pleiomorphic adenoma gene-like 2 | 0.00671527 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00671257 |
| CERK | ceramide kinase | 0.00670294 |
| FTL | ferritin, light polypeptide | 0.00667198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0184739 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0152446 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0149428 |
| THBS1 | thrombospondin 1 | -0.014891 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.0142803 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.0135268 |
| TSPAN4 | tetraspanin 4 | -0.0134742 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.0132879 |
| DSP | desmoplakin | -0.0122054 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0119327 |
| LEFTY1 | left-right determination factor 1 | -0.0118419 |
| CREBL2 | cAMP responsive element binding protein-like 2 | -0.0118318 |
| AOC1 | amine oxidase, copper containing 1 | -0.0117749 |
| BGN | biglycan | -0.0116284 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0114968 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.011496 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0114915 |
| S100A7 | S100 calcium binding protein A7 | -0.0113421 |
| PYCARD | PYD and CARD domain containing | -0.0112071 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.0111942 |
| HMGB3 | high mobility group box 3 | -0.011186 |
| SELENOW | selenoprotein W | -0.0109449 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0108842 |
| ASPN | asporin | -0.0108459 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.0106252 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0105808 |
| PLK1 | polo-like kinase 1 | -0.0105263 |
| DPEP1 | dipeptidase 1 (renal) | -0.0103361 |
| LST1 | leukocyte specific transcript 1 | -0.010308 |
| RGS10 | regulator of G-protein signaling 10 | -0.0102976 |
| TXNDC9 | thioredoxin domain containing 9 | -0.010284 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0102382 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0102091 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0101891 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.0101189 |
| HTRA1 | HtrA serine peptidase 1 | -0.0100399 |
| THBS2 | thrombospondin 2 | -0.0100141 |
| CTSD | cathepsin D | -0.00997786 |
| IPO13 | importin 13 | -0.00984469 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00981588 |
| MX2 | MX dynamin-like GTPase 2 | -0.00980706 |
| IFI35 | interferon-induced protein 35 | -0.0097733 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00976209 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.0097164 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.00969104 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0096686 |
| HIST3H2A | histone cluster 3, H2a | -0.00958961 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0094231 |
| APOD | apolipoprotein D | -0.00941545 |
| GUCY2C | guanylate cyclase 2C | -0.009408 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00934758 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00928189 |
| LRRC17 | leucine rich repeat containing 17 | -0.00928045 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00925334 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00921101 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00920445 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00917183 |
| CD9 | CD9 molecule | -0.00914074 |
| SDC1 | syndecan 1 | -0.00907436 |
| CAPN3 | calpain 3, (p94) | -0.00903724 |
| VCAN | versican | -0.00897539 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00895637 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00891161 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00877254 |
| CRYL1 | crystallin, lambda 1 | -0.00865295 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00861553 |
| NKG7 | natural killer cell granule protein 7 | -0.00860461 |
| C9ORF16 | chromosome 9 open reading frame 16 | -0.00856041 |
| SDC4 | syndecan 4 | -0.00851121 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00850599 |
| SATB2 | SATB homeobox 2 | -0.0084878 |
| OLFM4 | olfactomedin 4 | -0.00840369 |
| GLO1 | glyoxalase I | -0.00838267 |
| RGS4 | regulator of G-protein signaling 4 | -0.00836205 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00831864 |
| TUBA1A | tubulin, alpha 1a | -0.00831547 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00830818 |
| IL7R | interleukin 7 receptor | -0.00825866 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0082496 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00824161 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00823703 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00823413 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00821172 |
| MMP1 | matrix metallopeptidase 1 | -0.00820912 |
| MMP11 | matrix metallopeptidase 11 | -0.00814068 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00812054 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00807891 |
| KLF10 | Kruppel-like factor 10 | -0.008068 |
| SELPLG | selectin P ligand | -0.00801547 |
| AREG | amphiregulin | -0.00800616 |
| KRT20 | keratin 20, type I | -0.00799029 |
| TMEM176A | transmembrane protein 176A | -0.00796047 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00794829 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00792383 |
| ARSL | arylsulfatase L | -0.007871 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00785265 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00784942 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00784649 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00783515 |
| NCALD | neurocalcin delta | -0.00782492 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.00780272 |
| ADAP1 | ArfGAP with dual PH domains 1 | -0.00775522 |
| GIPC1 | GIPC PDZ domain containing family, member 1 | -0.00775002 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00773904 |
| CRYM | crystallin, mu | -0.00772274 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00772208 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00771246 |
| SMAGP | small cell adhesion glycoprotein | -0.00762402 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.00762156 |
| NARF | nuclear prelamin A recognition factor | -0.00760775 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00757658 |
| TRIM8 | tripartite motif containing 8 | -0.00757038 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00755815 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00754999 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0075217 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | -0.0075202 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00749402 |
| AK4 | adenylate kinase 4 | -0.00749155 |
| LCN2 | lipocalin 2 | -0.00747345 |
| SLC38A10 | solute carrier family 38, member 10 | -0.00746512 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00743221 |
| INHBA | inhibin, beta A | -0.00742775 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00742667 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00742558 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00742532 |
| WDR7 | WD repeat domain 7 | -0.00738982 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00738273 |
| C6 | complement component 6 | -0.00735737 |
| NOX1 | NADPH oxidase 1 | -0.00735552 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00732967 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00732799 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00730143 |
| TBCD | tubulin folding cofactor D | -0.00729322 |
| VDAC3 | voltage-dependent anion channel 3 | -0.00729109 |
| PLIN2 | perilipin 2 | -0.00727617 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00726701 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00726432 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00723968 |
| C3 | complement component 3 | -0.00723208 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00721264 |
| EIF4E2 | eukaryotic translation initiation factor 4E family member 2 | -0.00720989 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00719872 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00719752 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00719012 |
| CD7 | CD7 molecule | -0.00718181 |
| CA6 | carbonic anhydrase VI | -0.00717291 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00717285 |
| ADD3 | adducin 3 (gamma) | -0.00715622 |
| CHEK2 | checkpoint kinase 2 | -0.00715117 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00714815 |
| ATP10A | ATPase, class V, type 10A | -0.00714578 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.00714332 |
| TMC5 | transmembrane channel-like 5 | -0.00714043 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | -0.00713346 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00712004 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00711746 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00709714 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0070796 |
| FABP1 | fatty acid binding protein 1, liver | -0.00705854 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00704589 |
| TPMT | thiopurine S-methyltransferase | -0.00702001 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | -0.00701144 |
| CCDC92 | coiled-coil domain containing 92 | -0.00698988 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00698863 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00698153 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.0069522 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.0069419 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00693788 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00693159 |
| CLCA1 | chloride channel accessory 1 | -0.00691758 |
| PRKCQ | protein kinase C, theta | -0.0069096 |
| AGRN | agrin | -0.00690277 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00689036 |
| SFXN3 | sideroflexin 3 | -0.00686639 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.00686001 |
| COL5A2 | collagen, type V, alpha 2 | -0.00683565 |
| TNS3 | tensin 3 | -0.00682675 |
| RPS5 | ribosomal protein S5 | -0.00682508 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00681516 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.00680759 |
| RNF144A | ring finger protein 144A | -0.00680076 |
| BICC1 | BicC family RNA binding protein 1 | -0.00679125 |
| EGR3 | early growth response 3 | -0.00677508 |
| TLR4 | toll-like receptor 4 | -0.00677232 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00675381 |
| GJB1 | gap junction protein, beta 1, 32kDa | -0.00672736 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00672436 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00672184 |
| LACTB2 | lactamase, beta 2 | -0.00670239 |
| ASRGL1 | asparaginase like 1 | -0.00670117 |
| FAM162A | family with sequence similarity 162, member A | -0.00668862 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | -0.00666949 |
| CYP11B2 | cytochrome P450, family 11, subfamily B, polypeptide 2 | -0.00666038 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00665415 |
| TAPBP | TAP binding protein (tapasin) | -0.00665038 |
| EVI2A | ecotropic viral integration site 2A | -0.00663821 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00662671 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00662506 |
| CLDN3 | claudin 3 | -0.00661596 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00661191 |
| ALAD | aminolevulinate dehydratase | -0.00660837 |
| EPCAM | epithelial cell adhesion molecule | -0.00660427 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -0.00656366 |
| CHKB | choline kinase beta | -0.00655498 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00653946 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00653898 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00651679 |
| XPO7 | exportin 7 | -0.00651325 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00650571 |
| ANXA4 | annexin A4 | -0.0064877 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -0.00648715 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.0064804 |
| TOX3 | TOX high mobility group box family member 3 | -0.00647572 |
| KLK1 | kallikrein 1 | -0.00645045 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00642086 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | -0.00640025 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00638769 |
| FGFR4 | fibroblast growth factor receptor 4 | -0.00637769 |
| H2AX | H2A.X variant histone | -0.00635603 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00634938 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00634096 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00633694 |
| MXRA7 | matrix-remodelling associated 7 | -0.00633251 |
| TTC38 | tetratricopeptide repeat domain 38 | -0.00632446 |
| TMEM63A | transmembrane protein 63A | -0.0063236 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00632157 |
| ITM2C | integral membrane protein 2C | -0.00631265 |
| CTSH | cathepsin H | -0.00630402 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00629538 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.00627528 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0062534 |
| C5ORF15 | chromosome 5 open reading frame 15 | -0.00625283 |
| MAL | mal, T-cell differentiation protein | -0.00623706 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00621038 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0061996 |
| SLC44A4 | solute carrier family 44, member 4 | -0.0061989 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.00619365 |
| WBP1L | WW domain binding protein 1-like | -0.0061918 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.00619143 |
| DDHD2 | DDHD domain containing 2 | -0.00618679 |
| NANS | N-acetylneuraminic acid synthase | -0.00618097 |
| IL7 | interleukin 7 | -0.00617757 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0061767 |
| DIPK1A | divergent protein kinase domain 1A | -0.00617089 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00616231 |
| HOPX | HOP homeobox | -0.00614774 |
| CHPF | chondroitin polymerizing factor | -0.00614663 |
| OGDHL | oxoglutarate dehydrogenase-like | -0.0061453 |
| DPH5 | diphthamide biosynthesis 5 | -0.00614275 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.0061215 |
