KIF12 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description kinesin family member 12|KIF12 is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that play important roles in intracellular transport and cell division (Nakagawa et al., 1997 [PubMed 9275178]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 113220)
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Genes

357 genes differentially expressed following the KIF12 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.11016
NRG4 neuregulin 4 2.11016
IMPG2 interphotoreceptor matrix proteoglycan 2 2.11016
COL19A1 collagen, type XIX, alpha 1 2.11016
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 2.11016
PDZD7 PDZ domain containing 7 2.11016
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.11016
HNF1A HNF1 homeobox A 2.11016
OTOF otoferlin 2.11016
C4ORF50 chromosome 4 open reading frame 50 2.11016
OR5B12 olfactory receptor, family 5, subfamily B, member 12 2.11016
CALCA calcitonin-related polypeptide alpha 2.11016
IDO2 indoleamine 2,3-dioxygenase 2 2.11016
TEX38 testis expressed 38 2.11016
SCRT2 scratch family zinc finger 2 2.11016
S1PR5 sphingosine-1-phosphate receptor 5 2.11016
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.11016
KLHL1 kelch-like family member 1 2.11016
TMEM86A transmembrane protein 86A 2.11016
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.11016
SUSD2 sushi domain containing 2 2.11016
MEIKIN meiotic kinetochore factor 2.11016
THSD8 thrombospondin type 1 domain containing 8 2.11016
ADCY10 adenylate cyclase 10 (soluble) 2.11016
IHO1 interactor of HORMAD1 1 2.11016
STRIT1 small transmembrane regulator of ion transport 1 2.11016
CCDC194 coiled-coil domain containing 194 2.11016
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.11016
IDUA iduronidase, alpha-L- 2.11016
CCDC116 coiled-coil domain containing 116 2.09943
FER1L6 fer-1-like family member 6 2.09943
LY86 lymphocyte antigen 86 2.09943
ZACN zinc activated ligand-gated ion channel 2.09943
SBK3 SH3 domain binding kinase family, member 3 2.09943
C9ORF152 chromosome 9 open reading frame 152 2.09943
PCDHA7 protocadherin alpha 7 2.09943
RAB41 RAB41, member RAS oncogene family 2.09943
TMEM229A transmembrane protein 229A 2.09943
PVRIG poliovirus receptor related immunoglobulin domain containing 2.09943
HHEX hematopoietically expressed homeobox 2.09943
OR2A25 olfactory receptor, family 2, subfamily A, member 25 2.09943
PLB1 phospholipase B1 2.09943
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 2.09943
ZEB2 zinc finger E-box binding homeobox 2 2.09943
PLAG1 pleiomorphic adenoma gene 1 2.09943
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.09943
TDRD1 tudor domain containing 1 2.09943
FGF22 fibroblast growth factor 22 2.09943
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.09943
GIMAP7 GTPase, IMAP family member 7 2.09943
DUSP10 dual specificity phosphatase 10 2.09943
ATG14 autophagy related 14 2.09943
CC2D2B coiled-coil and C2 domain containing 2B 2.09943
NUGGC nuclear GTPase, germinal center associated 2.09943
GJB3 gap junction protein, beta 3, 31kDa 2.09943
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.09943
CSMD3 CUB and Sushi multiple domains 3 2.09943
MSC musculin 2.09943
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.09943
TRIM73 tripartite motif containing 73 2.09943
AMTN amelotin 2.09943
TMEM191B transmembrane protein 191B 2.09943
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.09943
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.09943
ASPDH aspartate dehydrogenase domain containing 2.09943
CYTIP cytohesin 1 interacting protein 2.09943
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.09943
CABP4 calcium binding protein 4 2.09943
CA7 carbonic anhydrase VII 2.09943
PDYN prodynorphin 2.09943
SOX10 SRY (sex determining region Y)-box 10 2.09943
MORN2 MORN repeat containing 2 2.09943
SPATA31F1 SPATA31 subfamily F member 1 2.09943
DIPK2B divergent protein kinase domain 2B 2.09943
HJV hemojuvelin BMP co-receptor 2.09943
CBLIF cobalamin binding intrinsic factor 2.09943
DEPP1 DEPP autophagy regulator 1 2.09943
AVPR1B arginine vasopressin receptor 1B 2.09943
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.09943
AANAT aralkylamine N-acetyltransferase 2.09943
CCER2 coiled-coil glutamate-rich protein 2 2.09943
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.09943
MYZAP myocardial zonula adherens protein 2.09943
ACYP2 acylphosphatase 2, muscle type 2.09943
JAML junction adhesion molecule like 2.09943
DUSP29 dual specificity phosphatase 29 2.09943
CHCT1 CHD1 helical C-terminal domain containing 1 2.09943
SPATA31H1 SPATA31 subfamily H member 1 2.09943
TEX53 testis expressed 53 2.09943
CPNE8-AS1 CPNE8 antisense RNA 1 2.09943
SPMIP3 sperm microtubule inner protein 3 2.09943
LINC02798 long intergenic non-protein coding RNA 2798 2.09943
H4C12 H4 clustered histone 12 2.09943
SERTM2 serine rich and transmembrane domain containing 2 2.09943
AKAIN1 A-kinase anchor inhibitor 1 2.09943
LOC124900192 uncharacterized LOC124900192 2.09943
CFAP276 cilia and flagella associated protein 276 2.09943
FNDC11 fibronectin type III domain containing 11 2.09943
ADRB1 adrenoceptor beta 1 2.09943
PAPOLG poly(A) polymerase gamma 2.09943
DEDD2 death effector domain containing 2 2.09943
COL6A6 collagen, type VI, alpha 6 2.09943
CHRD chordin 2.09943
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 2.09943
EDAR ectodysplasin A receptor 2.09943
TEX101 testis expressed 101 2.09943
PCDHB10 protocadherin beta 10 2.09943
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.09943
DMP1 dentin matrix acidic phosphoprotein 1 2.09943
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.09943
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.09943
TMCO2 transmembrane and coiled-coil domains 2 2.09943
ZNF25 zinc finger protein 25 2.09943
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.09943
BDKRB2 bradykinin receptor B2 2.09943
WNT16 wingless-type MMTV integration site family, member 16 2.09943
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.09943
TBX10 T-box 10 2.09943
GATA4 GATA binding protein 4 2.09943
PRDM7 PR domain containing 7 2.09943
FAM107A family with sequence similarity 107, member A 2.09943
OR2D2 olfactory receptor, family 2, subfamily D, member 2 2.09943
SAMD11 sterile alpha motif domain containing 11 2.09943
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.09943
CLSTN1 calsyntenin 1 2.09943
MTNR1B melatonin receptor 1B 2.09943
RAB2B RAB2B, member RAS oncogene family 2.09943
TMEM259 transmembrane protein 259 2.09943
TTI2 TELO2 interacting protein 2 2.09943
GOLGA6C golgin A6 family, member C 2.09943
WFDC8 WAP four-disulfide core domain 8 2.09943
PLET1 placenta expressed transcript 1 2.09943
SC5D sterol-C5-desaturase 2.09943
HKDC1 hexokinase domain containing 1 2.09943
IL36R interleukin 36 receptor 2.09943
PSKH2 protein serine kinase H2 2.09943
TRIM50 tripartite motif containing 50 2.09943
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.09943
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.09943
C9ORF64 chromosome 9 open reading frame 64 2.09943
CXCR6 chemokine (C-X-C motif) receptor 6 2.09943
C11ORF96 chromosome 11 open reading frame 96 2.09943
SMIM22 small integral membrane protein 22 2.09943
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 2.09943
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.09943
FBXO39 F-box protein 39 2.09943
PCDHGB1 protocadherin gamma subfamily B, 1 2.09943
LRCOL1 leucine rich colipase-like 1 2.09943
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.09943
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.09943
GAGE10 G antigen 10 2.09943
ULK1 unc-51 like autophagy activating kinase 1 2.09943
BTNL2 butyrophilin-like 2 2.09943
HCK HCK proto-oncogene, Src family tyrosine kinase 2.09943
BCO1 beta-carotene oxygenase 1 2.09943
PCDH10 protocadherin 10 2.09943
IFI35 interferon-induced protein 35 2.09943
STOM stomatin 2.09943
SLC25A34 solute carrier family 25, member 34 2.09943
APEH acylaminoacyl-peptide hydrolase 2.09943
C1ORF105 chromosome 1 open reading frame 105 2.09943
CAPSL calcyphosine-like 2.09943
ADAP1 ArfGAP with dual PH domains 1 2.09943
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.09943
OTP orthopedia homeobox 2.09943
GBX1 gastrulation brain homeobox 1 2.09943
TTC22 tetratricopeptide repeat domain 22 2.09943
UBXN10 UBX domain protein 10 2.09943
NID2 nidogen 2 (osteonidogen) 2.09943
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 2.09943
SSC5D scavenger receptor cysteine rich family, 5 domains 2.09943
HP haptoglobin 2.09943
LRRK2 leucine-rich repeat kinase 2 2.09943
GPS1 G protein pathway suppressor 1 2.09943
KLK7 kallikrein-related peptidase 7 2.09943
KLK5 kallikrein-related peptidase 5 2.09943
FSHR follicle stimulating hormone receptor 2.09943
CHIT1 chitinase 1 (chitotriosidase) 2.09943
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.09943
OCM oncomodulin 2.09943
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.09943
CFI complement factor I 2.09943
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.09943
LVRN laeverin 2.09943
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.09943
FAM9B family with sequence similarity 9, member B 2.09943
STAP1 signal transducing adaptor family member 1 2.09943
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.09943
FGF9 fibroblast growth factor 9 2.09943
SCIN scinderin 2.09943
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.09943
GALP galanin-like peptide 2.09943
PITX2 paired-like homeodomain 2 2.09943
APOA1 apolipoprotein A-I 2.09943
IRX1 iroquois homeobox 1 2.09943
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 2.09943
RNF39 ring finger protein 39 2.09943
SUSD6 sushi domain containing 6 2.09943
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.09943
LRRC63 leucine rich repeat containing 63 2.09943
RFX6 regulatory factor X, 6 2.09943
TAS2R13 taste receptor, type 2, member 13 2.09943
CORO6 coronin 6 2.09943
ADH6 alcohol dehydrogenase 6 (class V) 2.09943
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 2.09943
BMP5 bone morphogenetic protein 5 2.09943
PGBD2 piggyBac transposable element derived 2 2.09943
GALR3 galanin receptor 3 2.09943
TMC8 transmembrane channel-like 8 2.09943
HMGA2 high mobility group AT-hook 2 2.09943
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.09943
GRAP2 GRB2-related adaptor protein 2 2.09943
ZBED1 zinc finger, BED-type containing 1 2.09943
LACTB lactamase, beta 2.09943
PATE2 prostate and testis expressed 2 2.09943
MT1E metallothionein 1E 2.09943
CARNS1 carnosine synthase 1 2.09943
PAGE2B P antigen family, member 2B 2.09943
NUTM2F NUT family member 2F 2.09943
RBSN rabenosyn, RAB effector 2.09943
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.09943
SUN3 Sad1 and UNC84 domain containing 3 2.09943
C9ORF50 chromosome 9 open reading frame 50 2.09943
PRSS54 protease, serine, 54 2.09943
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.09943
DUOXA1 dual oxidase maturation factor 1 2.09943
OR10G3 olfactory receptor, family 10, subfamily G, member 3 2.09943
TGM3 transglutaminase 3 2.09943
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.09943
SAP25 Sin3A-associated protein, 25kDa 2.09943
ADRA1D adrenoceptor alpha 1D 2.09943
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.09943
TEX35 testis expressed 35 2.09943
MLKL mixed lineage kinase domain-like 2.09868
LY6E lymphocyte antigen 6 complex, locus E 2.09638
MRPS5 mitochondrial ribosomal protein S5 2.09619
TRAIP TRAF interacting protein 2.09081
PTCH1 patched 1 2.08406
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 2.07901
ZNF106 zinc finger protein 106 2.07737
PBK PDZ binding kinase 2.06225
LRP6 low density lipoprotein receptor-related protein 6 2.06055
GPR87 G protein-coupled receptor 87 2.05362
RHOH ras homolog family member H 2.04486
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 2.04115
RTN3 reticulon 3 2.03128

decreased expression

Symbol Name Standardized Value
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.11016
ZNF573 zinc finger protein 573 -2.11016
NEMP2 nuclear envelope integral membrane protein 2 -2.11016
EIF5B eukaryotic translation initiation factor 5B -2.11016
C8ORF48 chromosome 8 open reading frame 48 -2.09943
MRPL57 mitochondrial ribosomal protein L57 -2.09943
PDIA6 protein disulfide isomerase family A, member 6 -2.09943
PGAM2 phosphoglycerate mutase 2 (muscle) -2.09943
CCNJL cyclin J-like -2.09943
CD1D CD1d molecule -2.09943
TOR4A torsin family 4, member A -2.09943
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E -2.09943
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -2.09943
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -2.09943
REM2 RAS (RAD and GEM)-like GTP binding 2 -2.09943
SP2 Sp2 transcription factor -2.09943
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 -2.09943
RNF4 ring finger protein 4 -2.09943
HES6 hes family bHLH transcription factor 6 -2.09943
MROH1 maestro heat-like repeat family member 1 -2.09943
ERMARD ER membrane-associated RNA degradation -2.09943
KAT8 K(lysine) acetyltransferase 8 -2.09943
SFXN1 sideroflexin 1 -2.09943
NFAM1 NFAT activating protein with ITAM motif 1 -2.09943
KSR2 kinase suppressor of ras 2 -2.09943
FGF23 fibroblast growth factor 23 -2.09943
RCOR3 REST corepressor 3 -2.09943
ZNF853 zinc finger protein 853 -2.09943
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -2.09943
RPL23 ribosomal protein L23 -2.09943
RPL22 ribosomal protein L22 -2.09943
PLCZ1 phospholipase C, zeta 1 -2.09943
MLX MLX, MAX dimerization protein -2.09943
ZNF528 zinc finger protein 528 -2.09943
STAT2 signal transducer and activator of transcription 2, 113kDa -2.09943
CCN3 cellular communication network factor 3 -2.09943
MARCHF9 membrane associated ring-CH-type finger 9 -2.09943
C7ORF57 chromosome 7 open reading frame 57 -2.09943
CCDC124 coiled-coil domain containing 124 -2.09943
SLC45A3 solute carrier family 45, member 3 -2.09943
C7orf78 chromosome 7 open reading frame 78 -2.09943
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -2.09943
SNRPC small nuclear ribonucleoprotein polypeptide C -2.09943
PTPRG protein tyrosine phosphatase, receptor type, G -2.09943
LGALS7B lectin, galactoside-binding, soluble, 7B -2.09943
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.09943
PRADC1 protease-associated domain containing 1 -2.09943
ZIC1 Zic family member 1 -2.09943
MTMR1 myotubularin related protein 1 -2.09943
ARMH2 armadillo like helical domain containing 2 -2.09943
CUEDC2 CUE domain containing 2 -2.09943
F11 coagulation factor XI -2.09943
TPGS2 tubulin polyglutamylase complex subunit 2 -2.09943
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 -2.09943
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 -2.09943
CXCR4 chemokine (C-X-C motif) receptor 4 -2.09943
KIF21B kinesin family member 21B -2.09943
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing -2.09943
AMIGO1 adhesion molecule with Ig-like domain 1 -2.09943
CERS4 ceramide synthase 4 -2.09943
MAN1A2 mannosidase, alpha, class 1A, member 2 -2.09943
CCDC22 coiled-coil domain containing 22 -2.09943
BMPER BMP binding endothelial regulator -2.09943
SYT4 synaptotagmin IV -2.09943
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.09943
ZNF658 zinc finger protein 658 -2.09943
SSRP1 structure specific recognition protein 1 -2.09943
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.09943
TMEM31 transmembrane protein 31 -2.09943
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -2.09943
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.09943
EPHA8 EPH receptor A8 -2.09943
PDHB pyruvate dehydrogenase (lipoamide) beta -2.09943
SRRM4 serine/arginine repetitive matrix 4 -2.09943
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.09943
MRPL48 mitochondrial ribosomal protein L48 -2.09943
BCAS4 breast carcinoma amplified sequence 4 -2.09943
SLC51A solute carrier family 51, alpha subunit -2.09943
TSKS testis-specific serine kinase substrate -2.09943
RIOK1 RIO kinase 1 -2.09943
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -2.09943
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 -2.09943
TMPPE transmembrane protein with metallophosphoesterase domain -2.09943
TCF7 transcription factor 7 (T-cell specific, HMG-box) -2.09943
LXN latexin -2.09943
MIXL1 Mix paired-like homeobox -2.09943
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.09943
CPE carboxypeptidase E -2.09943
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.09943
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.09347
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.09347
IRX2 iroquois homeobox 2 -2.07901
TUSC2 tumor suppressor candidate 2 -2.05822
AFP alpha-fetoprotein -2.05822
NBPF15 neuroblastoma breakpoint family, member 15 -2.05822
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -2.05822
ZFP2 ZFP2 zinc finger protein -2.05362
DGKD diacylglycerol kinase, delta 130kDa -2.05362
RFX8 RFX family member 8, lacking RFX DNA binding domain -2.05362
CFD complement factor D (adipsin) -2.05362
KCTD19 potassium channel tetramerization domain containing 19 -2.05362
TCL1B T-cell leukemia/lymphoma 1B -2.05362
SCN4B sodium channel, voltage gated, type IV beta subunit -2.05362
USF1 upstream transcription factor 1 -2.05362
NIPAL3 NIPA-like domain containing 3 -2.05362
TRIM47 tripartite motif containing 47 -2.05362
PRSS51 protease, serine, 51 -2.05362
EXOC3L2 exocyst complex component 3-like 2 -2.05362
NAP1L5 nucleosome assembly protein 1-like 5 -2.05362
LIPE lipase, hormone-sensitive -2.03888
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.00443