KIF22 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description kinesin family member 22|The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 3835)
Similar Terms
Downloads & Tools

Genes

355 genes differentially expressed following the KIF22 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PCDHGB5 protocadherin gamma subfamily B, 5 3.45437
DUSP9 dual specificity phosphatase 9 3.45437
NT5C1B 5'-nucleotidase, cytosolic IB 3.45437
DLX4 distal-less homeobox 4 3.45437
GMFG glia maturation factor, gamma 3.45437
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 3.45437
IGSF23 immunoglobulin superfamily, member 23 3.45437
DOK5 docking protein 5 3.45437
NWD1 NACHT and WD repeat domain containing 1 3.45437
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.45437
GLT6D1 glycosyltransferase 6 domain containing 1 3.45437
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 3.45437
CD53 CD53 molecule 3.45437
TDRD10 tudor domain containing 10 3.45437
ZNF436 zinc finger protein 436 3.45437
FPR1 formyl peptide receptor 1 3.45437
SGPP2 sphingosine-1-phosphate phosphatase 2 3.45437
TEX53 testis expressed 53 3.45437
SMIM32 small integral membrane protein 32 3.45437
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 3.45437
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.45437
RNASE6 ribonuclease, RNase A family, k6 3.45437
PASD1 PAS domain containing 1 3.45437
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 3.45437
FOXN4 forkhead box N4 3.45437
CCDC187 coiled-coil domain containing 187 3.45437
TSGA13 testis specific, 13 3.33122
GLUD2 glutamate dehydrogenase 2 3.33122
PON1 paraoxonase 1 3.33122
SCGN secretagogin, EF-hand calcium binding protein 3.33122
SSTR1 somatostatin receptor 1 3.33122
CARD16 caspase recruitment domain family, member 16 3.33122
HNF4A hepatocyte nuclear factor 4, alpha 3.33122
TXLNB taxilin beta 3.33122
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.33122
ALB albumin 3.33122
HCRTR2 hypocretin (orexin) receptor 2 3.33122
CD274 CD274 molecule 3.33122
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 3.33122
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 3.33122
ADTRP androgen-dependent TFPI-regulating protein 3.33122
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 3.33122
TBATA thymus, brain and testes associated 3.33122
LONRF3 LON peptidase N-terminal domain and ring finger 3 3.33122
CPLX4 complexin 4 3.33122
TMC3 transmembrane channel-like 3 3.33122
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 3.33122
C9ORF152 chromosome 9 open reading frame 152 3.33122
C1ORF141 chromosome 1 open reading frame 141 3.33122
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 3.33122
GFI1 growth factor independent 1 transcription repressor 3.33122
RNF39 ring finger protein 39 3.33122
RTP3 receptor (chemosensory) transporter protein 3 3.33122
LYZL6 lysozyme-like 6 3.33122
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 3.33122
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 3.33122
LRRC56 leucine rich repeat containing 56 3.33122
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 3.33122
ACOT12 acyl-CoA thioesterase 12 3.33122
SPATA31H1 SPATA31 subfamily H member 1 3.33122
AVPR1B arginine vasopressin receptor 1B 3.33122
MYH1 myosin, heavy chain 1, skeletal muscle, adult 3.33122
BNC1 basonuclin 1 3.33122
HOXC12 homeobox C12 3.33122
AMY1A amylase, alpha 1A (salivary) 3.33122
LOC124906892 uncharacterized LOC124906892 3.33122
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 3.33122
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 3.33122
LMNTD1 lamin tail domain containing 1 3.33122
MCHR2 melanin-concentrating hormone receptor 2 3.33122
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 3.33122
CIMIP2C ciliary microtubule inner protein 2C 3.33122
CPNE8-AS1 CPNE8 antisense RNA 1 3.33122
LOC124903233 uncharacterized LOC124903233 3.33122
H2AC19 H2A clustered histone 19 3.33122
ERFE erythroferrone 3.33122
CCN6 cellular communication network factor 6 3.33122
SMIM36 small integral membrane protein 36 3.33122
CCDC9B coiled-coil domain containing 9B 3.33122
H2BC1 H2B clustered histone 1 3.33122
TMPRSS7 transmembrane protease, serine 7 3.33122
TMPRSS3 transmembrane protease, serine 3 3.33122
TLR9 toll-like receptor 9 3.33122
SCRT1 scratch family zinc finger 1 3.33122
TMEM235 transmembrane protein 235 3.33122
CHRD chordin 3.33122
C9 complement component 9 3.33122
DNAI2 dynein, axonemal, intermediate chain 2 3.33122
ZNF98 zinc finger protein 98 3.33122
SLC22A14 solute carrier family 22, member 14 3.33122
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.33122
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.33122
GZMM granzyme M (lymphocyte met-ase 1) 3.33122
TUBA4B tubulin, alpha 4b 3.33122
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.33122
WNT9B wingless-type MMTV integration site family, member 9B 3.33122
NPIPB8 nuclear pore complex interacting protein family, member B8 3.33122
BLNK B-cell linker 3.33122
PGA5 pepsinogen 5, group I (pepsinogen A) 3.33122
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 3.33122
FAP fibroblast activation protein, alpha 3.33122
SH3TC2 SH3 domain and tetratricopeptide repeats 2 3.33122
TAS2R5 taste receptor, type 2, member 5 3.33122
CXCR6 chemokine (C-X-C motif) receptor 6 3.33122
CLIC3 chloride intracellular channel 3 3.33122
SUN3 Sad1 and UNC84 domain containing 3 3.33122
CLEC18C C-type lectin domain family 18, member C 3.33122
TECRL trans-2,3-enoyl-CoA reductase-like 3.33122
IL19 interleukin 19 3.33122
PXT1 peroxisomal, testis specific 1 3.33122
PCDH12 protocadherin 12 3.33122
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 3.33122
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.33122
RERGL RERG/RAS-like 3.33122
CLCA1 chloride channel accessory 1 3.33122
RNF123 ring finger protein 123 3.33122
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 3.33122
ITPKA inositol-trisphosphate 3-kinase A 3.33122
LMOD3 leiomodin 3 (fetal) 3.33122
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.33122
KRT15 keratin 15, type I 3.33122
ARR3 arrestin 3, retinal (X-arrestin) 3.33122
BTNL9 butyrophilin-like 9 3.33122
EFCAB3 EF-hand calcium binding domain 3 3.33122
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 3.33122
TRADD TNFRSF1A-associated via death domain 3.33122
APOC4 apolipoprotein C-IV 3.33122
EBF3 early B-cell factor 3 3.33122
TTC9B tetratricopeptide repeat domain 9B 3.33122
SPTBN5 spectrin, beta, non-erythrocytic 5 3.33122
PCDHGA3 protocadherin gamma subfamily A, 3 3.33122
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.33122
HGFAC HGF activator 3.33122
PCDHGA2 protocadherin gamma subfamily A, 2 3.33122
KRT17 keratin 17, type I 3.33122
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 3.33122
TSKS testis-specific serine kinase substrate 3.33122
FBXO40 F-box protein 40 3.33122
EPHB3 EPH receptor B3 3.33122
RGS8 regulator of G-protein signaling 8 3.33122
NKX6-1 NK6 homeobox 1 3.33122
NLRP6 NLR family, pyrin domain containing 6 3.33122
MYADML2 myeloid-associated differentiation marker-like 2 3.33122
NMBR neuromedin B receptor 3.33122
NLRP3 NLR family, pyrin domain containing 3 3.33122
GPR150 G protein-coupled receptor 150 3.33122
MEPE matrix extracellular phosphoglycoprotein 3.33122
CLEC18A C-type lectin domain family 18, member A 3.33122
LKAAEAR1 LKAAEAR motif containing 1 3.33122
SFTA2 surfactant associated 2 3.33122
DSPP dentin sialophosphoprotein 3.33122
PHACTR3 phosphatase and actin regulator 3 3.33122
PLCD4 phospholipase C, delta 4 3.33122
BCL2L15 BCL2-like 15 3.33122
PADI1 peptidyl arginine deiminase, type I 3.33122
SYTL4 synaptotagmin-like 4 3.33122
ZPLD1 zona pellucida-like domain containing 1 3.33122
PLA2G12B phospholipase A2, group XIIB 3.33122
PADI6 peptidyl arginine deiminase, type VI 3.33122
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 3.33122
NUTM2B NUT family member 2B 3.33122
TSPYL6 TSPY-like 6 3.33122
FBXO47 F-box protein 47 3.33122
DLX3 distal-less homeobox 3 3.33122
NOBOX NOBOX oogenesis homeobox 3.33122
DMRT2 doublesex and mab-3 related transcription factor 2 3.33122
OSBPL1A oxysterol binding protein-like 1A 3.25487
TBC1D3L TBC1 domain family, member 3L 3.23706
TDRD1 tudor domain containing 1 3.23706
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 3.19166
IL15RA interleukin 15 receptor, alpha 3.19166
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 3.19166
AFMID arylformamidase 3.11542
DRD3 dopamine receptor D3 3.05322
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 2.73955
TOP3A topoisomerase (DNA) III alpha 2.64189
AADAT aminoadipate aminotransferase 2.60152
LIN52 lin-52 DREAM MuvB core complex component 2.58617
CRACR2B calcium release activated channel regulator 2B 2.56878
YME1L1 YME1-like 1 ATPase 2.56584
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.56314
ANXA1 annexin A1 2.53067
AZI2 5-azacytidine induced 2 2.50887
MSL1 male-specific lethal 1 homolog (Drosophila) 2.50114
CFLAR CASP8 and FADD-like apoptosis regulator 2.49477
NRK Nik related kinase 2.46302
FBXL19 F-box and leucine-rich repeat protein 19 2.40875
ALPK1 alpha-kinase 1 2.35798
MCF2L MCF.2 cell line derived transforming sequence-like 2.33152
QPCT glutaminyl-peptide cyclotransferase 2.33152
C1QTNF1 C1q and tumor necrosis factor related protein 1 2.3006
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.3006
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 2.29525
MRPL24 mitochondrial ribosomal protein L24 2.23528
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 2.21593
INIP INTS3 and NABP interacting protein 2.20791
TMEM256 transmembrane protein 256 2.20615
AIP aryl hydrocarbon receptor interacting protein 2.17022
IL17D interleukin 17D 2.15508
MARK4 MAP/microtubule affinity-regulating kinase 4 2.15508
NLRP1 NLR family, pyrin domain containing 1 2.15508
ABLIM3 actin binding LIM protein family, member 3 2.15508
ETV7 ets variant 7 2.15508
CSP2 CS pseudogene 2 2.15508
NLRP10 NLR family, pyrin domain containing 10 2.15508
CA7 carbonic anhydrase VII 2.15508
DLC1 DLC1 Rho GTPase activating protein 2.15508
OR2A42 olfactory receptor, family 2, subfamily A, member 42 2.15508
ELMO3 engulfment and cell motility 3 2.15508
OSBPL7 oxysterol binding protein-like 7 2.15508
VWC2 von Willebrand factor C domain containing 2 2.15508
SUSD2 sushi domain containing 2 2.15508
LRP6 low density lipoprotein receptor-related protein 6 2.15508
ZBTB46 zinc finger and BTB domain containing 46 2.14841
LARP4 La ribonucleoprotein domain family, member 4 2.14709
CPEB2 cytoplasmic polyadenylation element binding protein 2 2.14622
FAM13C family with sequence similarity 13, member C 2.13939
RBBP6 retinoblastoma binding protein 6 2.11312
COX5B cytochrome c oxidase subunit Vb 2.11312
TMEM8B transmembrane protein 8B 2.11312
SMAD3 SMAD family member 3 2.10496
GOLGA3 golgin A3 2.09844
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.09844
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.09844
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.09844
ERMP1 endoplasmic reticulum metallopeptidase 1 2.0739
SUSD6 sushi domain containing 6 2.06834
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 2.06314
DDR2 discoidin domain receptor tyrosine kinase 2 2.06064
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 2.05673
OSBPL11 oxysterol binding protein-like 11 2.04631
GABARAPL1 GABA(A) receptor-associated protein like 1 2.042
INPP5F inositol polyphosphate-5-phosphatase F 2.01295

decreased expression

Symbol Name Standardized Value
ZAN zonadhesin (gene/pseudogene) -3.45437
LRRC8C leucine rich repeat containing 8 family, member C -3.45437
ADRA1A adrenoceptor alpha 1A -3.45437
CRYBB3 crystallin, beta B3 -3.45437
MVK mevalonate kinase -3.45437
BTN3A1 butyrophilin, subfamily 3, member A1 -3.45437
EFCAB8 EF-hand calcium binding domain 8 -3.45437
CCDC159 coiled-coil domain containing 159 -3.45437
BIN2 bridging integrator 2 -3.33122
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 -3.33122
AKAP3 A kinase (PRKA) anchor protein 3 -3.33122
AKR1D1 aldo-keto reductase family 1, member D1 -3.33122
KIRREL2 kin of IRRE like 2 (Drosophila) -3.33122
TTC36 tetratricopeptide repeat domain 36 -3.33122
COL11A2 collagen, type XI, alpha 2 -3.33122
MYO16 myosin XVI -3.33122
KIF22 kinesin family member 22 -3.33122
TTLL2 tubulin tyrosine ligase-like family member 2 -3.33122
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -3.33122
SHCBP1L SHC SH2-domain binding protein 1-like -3.33122
C8ORF48 chromosome 8 open reading frame 48 -3.33122
HORMAD2 HORMA domain containing 2 -3.33122
MUC20 mucin 20, cell surface associated -3.33122
ANPEP alanyl (membrane) aminopeptidase -3.33122
OXER1 oxoeicosanoid (OXE) receptor 1 -3.33122
NKPD1 NTPase, KAP family P-loop domain containing 1 -3.33122
CLIP4 CAP-GLY domain containing linker protein family, member 4 -3.33122
LDHAL6A lactate dehydrogenase A-like 6A -3.33122
C4ORF50 chromosome 4 open reading frame 50 -3.33122
PROZ protein Z, vitamin K-dependent plasma glycoprotein -3.33122
FMO2 flavin containing monooxygenase 2 (non-functional) -3.33122
TTLL9 tubulin tyrosine ligase-like family member 9 -3.33122
SRGN serglycin -3.33122
DUSP8 dual specificity phosphatase 8 -3.33122
ANGPTL8 angiopoietin like 8 -3.33122
PLPP4 phospholipid phosphatase 4 -3.33122
DEFB131B defensin beta 131B -3.33122
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -3.33122
TBXA2R thromboxane A2 receptor -3.33122
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -3.33122
NR1I3 nuclear receptor subfamily 1, group I, member 3 -3.33122
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -3.33122
F2RL2 coagulation factor II (thrombin) receptor-like 2 -3.33122
C1QTNF4 C1q and tumor necrosis factor related protein 4 -3.26275
DCPS decapping enzyme, scavenger -3.01038
TNPO2 transportin 2 -2.95098
PCP4 Purkinje cell protein 4 -2.94746
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 -2.87823
JAKMIP1 janus kinase and microtubule interacting protein 1 -2.86839
RANBP17 RAN binding protein 17 -2.83482
GRB2 growth factor receptor-bound protein 2 -2.79724
LARP7 La ribonucleoprotein domain family, member 7 -2.78394
CDCA3 cell division cycle associated 3 -2.63226
ZNF501 zinc finger protein 501 -2.62974
RTN3 reticulon 3 -2.60383
ZBTB41 zinc finger and BTB domain containing 41 -2.58542
ZC2HC1A zinc finger, C2HC-type containing 1A -2.56878
THBS3 thrombospondin 3 -2.54885
ZBED5 zinc finger, BED-type containing 5 -2.54026
MATN4 matrilin 4 -2.53792
TRIL TLR4 interactor with leucine-rich repeats -2.50887
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -2.50649
WNK4 WNK lysine deficient protein kinase 4 -2.47378
SIRAL2 SIR2 antiphage like 2 -2.47378
EGFL6 EGF-like-domain, multiple 6 -2.47378
MYH10 myosin, heavy chain 10, non-muscle -2.4721
PTPA protein phosphatase 2 phosphatase activator -2.46674
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -2.46674
MAOB monoamine oxidase B -2.45803
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -2.45803
CNTN2 contactin 2 (axonal) -2.45803
ANGPTL1 angiopoietin-like 1 -2.45803
LMOD1 leiomodin 1 (smooth muscle) -2.42677
LRRC17 leucine rich repeat containing 17 -2.42677
DCDC2 doublecortin domain containing 2 -2.40875
HRK harakiri, BCL2 interacting protein -2.39135
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -2.35798
BNIPL BCL2/adenovirus E1B 19kD interacting protein like -2.35798
EIF1 eukaryotic translation initiation factor 1 -2.35798
CHKA choline kinase alpha -2.34883
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.34666
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -2.34524
SLC10A7 solute carrier family 10, member 7 -2.34007
DMXL1 Dmx-like 1 -2.33511
PHF5A PHD finger protein 5A -2.33511
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -2.33152
TSEN15 TSEN15 tRNA splicing endonuclease subunit -2.32069
HYPK huntingtin interacting protein K -2.27114
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -2.27114
CHL1 cell adhesion molecule L1-like -2.27114
AGMO alkylglycerol monooxygenase -2.20677
CILK1 ciliogenesis associated kinase 1 -2.19015
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.19015
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.16215
STN1 STN1 subunit of CST complex -2.15742
EIF3K eukaryotic translation initiation factor 3, subunit K -2.15508
TUBGCP2 tubulin, gamma complex associated protein 2 -2.15508
COL8A1 collagen, type VIII, alpha 1 -2.14841
CENPU centromere protein U -2.13643
C19ORF84 chromosome 19 open reading frame 84 -2.13555
LRRC75B leucine rich repeat containing 75B -2.11365
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.11312
PGM2 phosphoglucomutase 2 -2.11312
FYTTD1 forty-two-three domain containing 1 -2.11312
FES FES proto-oncogene, tyrosine kinase -2.10565
ACBD6 acyl-CoA binding domain containing 6 -2.09844
FKTN fukutin -2.09844
EMD emerin -2.09731
CARS1 cysteinyl-tRNA synthetase 1 -2.09308
CAND2 cullin-associated and neddylation-dissociated 2 (putative) -2.08605
DAAM2 dishevelled associated activator of morphogenesis 2 -2.07358
RUNX2 runt-related transcription factor 2 -2.06768
ZC3H8 zinc finger CCCH-type containing 8 -2.06715
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.042
FAXC failed axon connections homolog (Drosophila) -2.03992
SOCS1 suppressor of cytokine signaling 1 -2.02319
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.02319
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 -2.02319
FGD3 FYVE, RhoGEF and PH domain containing 3 -2.02319
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.02295
C2ORF92 chromosome 2 open reading frame 92 -2.01295
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -2.00401