KIT Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog|This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3815)
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100 substrates of the kinase KIT from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
SEC14L3 SEC14-like 3 (S. cerevisiae) 99.98
SEC14L2 SEC14-like 2 (S. cerevisiae) 99.98
MRPS27 mitochondrial ribosomal protein S27 99.93
ALOX5 arachidonate 5-lipoxygenase 99.91
EIF3I eukaryotic translation initiation factor 3, subunit I 99.87
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 99.78
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 99.74
EIF1 eukaryotic translation initiation factor 1 99.63
EIF1B eukaryotic translation initiation factor 1B 99.63
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 99.45
RTN4 reticulon 4 99.43
PM20D2 peptidase M20 domain containing 2 99.43
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 99.41
N4BP3 NEDD4 binding protein 3 99.32
UMPS uridine monophosphate synthetase 99.28
ZNF169 zinc finger protein 169 99.26
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 99.25
FDFT1 farnesyl-diphosphate farnesyltransferase 1 99.19
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 99.13
LURAP1L leucine rich adaptor protein 1-like 99.12
SIPA1L1 signal-induced proliferation-associated 1 like 1 99.08
PTPN7 protein tyrosine phosphatase, non-receptor type 7 98.99
IRS4 insulin receptor substrate 4 98.96
SH2D3C SH2 domain containing 3C 98.91
CCT8 chaperonin containing TCP1, subunit 8 (theta) 98.9
CHRM2 cholinergic receptor, muscarinic 2 98.78
EML4 echinoderm microtubule associated protein like 4 98.64
CNOT9 CCR4-NOT transcription complex subunit 9 98.55
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 98.53
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 98.51
MCC mutated in colorectal cancers 98.49
CD300LB CD300 molecule-like family member b 98.49
TRPV2 transient receptor potential cation channel, subfamily V, member 2 98.47
TLK1 tousled-like kinase 1 98.45
CEP170B centrosomal protein 170B 98.43
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 98.405
DLG3 discs, large homolog 3 (Drosophila) 98.385
SH2D1B SH2 domain containing 1B 98.34
SHROOM1 shroom family member 1 98.25
ARHGAP30 Rho GTPase activating protein 30 98.2
TRIOBP TRIO and F-actin binding protein 98.12
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 98.09
MAT2A methionine adenosyltransferase II, alpha 97.96
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 97.96
LRRK1 leucine-rich repeat kinase 1 97.94
HDAC6 histone deacetylase 6 97.86
CHD2 chromodomain helicase DNA binding protein 2 97.83
CHN2 chimerin 2 97.815
ZCCHC3 zinc finger, CCHC domain containing 3 97.79
PDCD5 programmed cell death 5 97.7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 97.66
FKBP5 FK506 binding protein 5 97.62
TLK2 tousled-like kinase 2 97.46
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 97.44
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 97.4
SIGLEC10 sialic acid binding Ig-like lectin 10 97.39
PLPPR4 phospholipid phosphatase related 4 97.39
TRPC6 transient receptor potential cation channel, subfamily C, member 6 97.33
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 97.29
OPHN1 oligophrenin 1 97.27
KCTD12 potassium channel tetramerization domain containing 12 97.26
HAVCR1 hepatitis A virus cellular receptor 1 97.24
PARD6B par-6 family cell polarity regulator beta 97.16
DDIAS DNA damage-induced apoptosis suppressor 97.15
CORO1C coronin, actin binding protein, 1C 97.09
PHLDB3 pleckstrin homology-like domain, family B, member 3 97.02
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 96.98
CHAF1B chromatin assembly factor 1, subunit B (p60) 96.94
PLS3 plastin 3 96.93
PTBP3 polypyrimidine tract binding protein 3 96.89
MAK male germ cell-associated kinase 96.8
LIFR leukemia inhibitory factor receptor alpha 96.78
CLEC12B C-type lectin domain family 12, member B 96.78
GPATCH11 G patch domain containing 11 96.78
EPM2AIP1 EPM2A (laforin) interacting protein 1 96.67
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 96.52
SMG8 SMG8 nonsense mediated mRNA decay factor 96.43
USP31 ubiquitin specific peptidase 31 96.35
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 96.32
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 96.28
THRB thyroid hormone receptor, beta 96.28
IL7R interleukin 7 receptor 96.26
GCSAML germinal center-associated, signaling and motility-like 96.145
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 96.11
MAPK6 mitogen-activated protein kinase 6 96.08
C1ORF210 chromosome 1 open reading frame 210 96.04
THEMIS2 thymocyte selection associated family member 2 95.97
KTN1 kinectin 1 (kinesin receptor) 95.91
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 95.89
ESYT2 extended synaptotagmin-like protein 2 95.88
NIPSNAP1 nipsnap homolog 1 (C. elegans) 95.83
SLITRK6 SLIT and NTRK-like family, member 6 95.81
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 95.77
MEMO1 mediator of cell motility 1 95.73
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 95.73
TIGIT T cell immunoreceptor with Ig and ITIM domains 95.73
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 95.69
F5 coagulation factor V (proaccelerin, labile factor) 95.54
CKAP4 cytoskeleton-associated protein 4 95.51
NUMA1 nuclear mitotic apparatus protein 1 95.49