KLE Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

236 genes mutated in the KLE cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ACSS1 acyl-CoA synthetase short-chain family member 1
ACTB actin, beta
ADNP activity-dependent neuroprotector homeobox
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOXE3 arachidonate lipoxygenase 3
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANAPC2 anaphase promoting complex subunit 2
ANKRD36C ankyrin repeat domain 36C
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARHGAP29 Rho GTPase activating protein 29
ARHGAP33 Rho GTPase activating protein 33
ARHGAP4 Rho GTPase activating protein 4
ARHGAP5 Rho GTPase activating protein 5
ARID1B AT rich interactive domain 1B (SWI1-like)
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASGR2 asialoglycoprotein receptor 2
ASTN2 astrotactin 2
ATG12 autophagy related 12
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP9A ATPase, class II, type 9A
BACE2 beta-site APP-cleaving enzyme 2
BAIAP3 BAI1-associated protein 3
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUD13 BUD13 homolog (S. cerevisiae)
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CASC1 cancer susceptibility candidate 1
CCDC144A coiled-coil domain containing 144A
CCDC150 coiled-coil domain containing 150
CCDC96 coiled-coil domain containing 96
CCM2 cerebral cavernous malformation 2
CCR6 chemokine (C-C motif) receptor 6
CDH23 cadherin-related 23
CEP192 centrosomal protein 192kDa
CFL2 cofilin 2 (muscle)
CNTN1 contactin 1
CNTN5 contactin 5
CNTNAP3B contactin associated protein-like 3B
COL6A3 collagen, type VI, alpha 3
COX6A1P2 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
CRIP2 cysteine-rich protein 2
CSMD1 CUB and Sushi multiple domains 1
CTCFL CCCTC-binding factor (zinc finger protein)-like
CYBB cytochrome b-245, beta polypeptide
DCST1 DC-STAMP domain containing 1
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DMRT3 doublesex and mab-3 related transcription factor 3
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM2 dynamin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK5 dedicator of cytokinesis 5
DOCK8 dedicator of cytokinesis 8
DSP desmoplakin
ECH1 enoyl CoA hydratase 1, peroxisomal
EDC4 enhancer of mRNA decapping 4
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMC6 ER membrane protein complex subunit 6
ENSA endosulfine alpha
ENTHD1 ENTH domain containing 1
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHA5 EPH receptor A5
EPHB6 EPH receptor B6
FAAH2 fatty acid amide hydrolase 2
FAM168B family with sequence similarity 168, member B
FBXO17 F-box protein 17
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGBP Fc fragment of IgG binding protein
FCRLB Fc receptor-like B
FGD4 FYVE, RhoGEF and PH domain containing 4
FOXN4 forkhead box N4
FSCN3 fascin actin-bundling protein 3, testicular
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GCNT6 glucosaminyl (N-acetyl) transferase 6
GLOD5 glyoxalase domain containing 5
GNAS GNAS complex locus
GPI glucose-6-phosphate isomerase
GPR50 G protein-coupled receptor 50
GSDMB gasdermin B
GYG1 glycogenin 1
GYPA glycophorin A (MNS blood group)
HDLBP high density lipoprotein binding protein
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HPS6 Hermansky-Pudlak syndrome 6
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT54 intraflagellar transport 54
IGF2 insulin-like growth factor 2
IPO5 importin 5
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
KIAA1524 KIAA1524
KIFC3 kinesin family member C3
KLHL30 kelch-like family member 30
KLHL5 kelch-like family member 5
KRTAP24-1 keratin associated protein 24-1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC3 laminin, gamma 3
LAMP1 lysosomal-associated membrane protein 1
LGALS4 lectin, galactoside-binding, soluble, 4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMX1B LIM homeobox transcription factor 1, beta
LPP LIM domain containing preferred translocation partner in lipoma
LRP1 low density lipoprotein receptor-related protein 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC16B leucine rich repeat containing 16B
LY75 lymphocyte antigen 75
MAGEC1 melanoma antigen family C1
MBOAT4 membrane bound O-acyltransferase domain containing 4
MDC1 mediator of DNA-damage checkpoint 1
MED9 mediator complex subunit 9
MEPCE methylphosphate capping enzyme
MICALCL MICAL C-terminal like
MME membrane metallo-endopeptidase
MRPL3 mitochondrial ribosomal protein L3
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTMR9 myotubularin related protein 9
MUC4 mucin 4, cell surface associated
MUC7 mucin 7, secreted
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXRA5 matrix-remodelling associated 5
MYO3A myosin IIIA
MYPOP Myb-related transcription factor, partner of profilin
NCAPG non-SMC condensin I complex, subunit G
NCKAP1L NCK-associated protein 1-like
NEB nebulin
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPBWR2 neuropeptides B/W receptor 2
NPC1L1 NPC1-like 1
NXPH1 neurexophilin 1
OPCML opioid binding protein/cell adhesion molecule-like
OR11A1 olfactory receptor, family 11, subfamily A, member 1
OR5P2 olfactory receptor, family 5, subfamily P, member 2
OSBPL3 oxysterol binding protein-like 3
OTUD6B OTU domain containing 6B
OXSR1 oxidative stress responsive 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB7 protocadherin beta 7
PCDHGB7 protocadherin gamma subfamily B, 7
PHKB phosphorylase kinase, beta
PKDCC protein kinase domain containing, cytoplasmic
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PNRC2 proline-rich nuclear receptor coactivator 2
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRDM9 PR domain containing 9
PRG4 proteoglycan 4
PROP1 PROP paired-like homeobox 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PUS3 pseudouridylate synthase 3
RAB9B RAB9B, member RAS oncogene family
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RALYL RALY RNA binding protein-like
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBBP4 retinoblastoma binding protein 4
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RFTN2 raftlin family member 2
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHOT2 ras homolog family member T2
RP1 retinitis pigmentosa 1 (autosomal dominant)
RTTN rotatin
RYR3 ryanodine receptor 3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SASS6 spindle assembly 6 homolog (C. elegans)
SCYL1 SCY1-like 1 (S. cerevisiae)
SEZ6 seizure related 6 homolog (mouse)
SGOL2 shugoshin-like 2 (S. pombe)
SGSM3 small G protein signaling modulator 3
SHCBP1L SHC SH2-domain binding protein 1-like
SHKBP1 SH3KBP1 binding protein 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRPB1 signal-regulatory protein beta 1
SKAP2 src kinase associated phosphoprotein 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLITRK3 SLIT and NTRK-like family, member 3
SLK STE20-like kinase
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SPAG8 sperm associated antigen 8
STK38 serine/threonine kinase 38
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAS2R31 taste receptor, type 2, member 31
TBL3 transducin (beta)-like 3
TCP10L2 t-complex 10-like 2
TEKT4 tektin 4
TFB2M transcription factor B2, mitochondrial
THBS2 thrombospondin 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMPRSS3 transmembrane protease, serine 3
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRAK2 trafficking protein, kinesin binding 2
TRAP1 TNF receptor-associated protein 1
TRIB3 tribbles pseudokinase 3
TRIM43 tripartite motif containing 43
TRIML2 tripartite motif family-like 2
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTN titin
UBA7 ubiquitin-like modifier activating enzyme 7
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VCPKMT valosin containing protein lysine (K) methyltransferase
VEZT vezatin, adherens junctions transmembrane protein
VRK2 vaccinia related kinase 2
WDR54 WD repeat domain 54
WFS1 Wolfram syndrome 1 (wolframin)
YBX3 Y box binding protein 3
ZFP1 ZFP1 zinc finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF385D zinc finger protein 385D
ZNF397 zinc finger protein 397
ZNF567 zinc finger protein 567
ZNF704 zinc finger protein 704
ZNF71 zinc finger protein 71
ZNF74 zinc finger protein 74
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
ZSCAN18 zinc finger and SCAN domain containing 18
ZXDB zinc finger, X-linked, duplicated B