KLF4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Kruppel-like factor 4 (gut)| (NCBI Entrez Gene Database, 9314)
External Link https://ncbi.nlm.nih.gov/gene/9314
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Genes

498 genes differentially expressed following the KLF4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0220539
WDR7 WD repeat domain 7 0.0183246
CXCL9 chemokine (C-X-C motif) ligand 9 0.0171617
GNAS GNAS complex locus 0.0160994
SSBP2 single-stranded DNA binding protein 2 0.0156825
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0148247
JCHAIN joining chain of multimeric IgA and IgM 0.0147983
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0142879
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0142058
S100A8 S100 calcium binding protein A8 0.0140906
MMP9 matrix metallopeptidase 9 0.013277
POU2AF1 POU class 2 associating factor 1 0.0119682
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.0118921
LYZ lysozyme 0.0118503
AKAP8 A kinase (PRKA) anchor protein 8 0.0111296
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0109422
CA12 carbonic anhydrase XII 0.0106158
CA2 carbonic anhydrase II 0.0105013
LTF lactotransferrin 0.0103605
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0102506
AMIGO2 adhesion molecule with Ig-like domain 2 0.0101217
LUM lumican 0.0100359
CSTA cystatin A (stefin A) 0.00977281
HBD hemoglobin, delta 0.00970954
PDE8B phosphodiesterase 8B 0.00961594
CXCL13 chemokine (C-X-C motif) ligand 13 0.00930083
ADAMDEC1 ADAM-like, decysin 1 0.00881802
CCL19 chemokine (C-C motif) ligand 19 0.00866012
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00835916
ZNF91 zinc finger protein 91 0.00818203
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0081699
BEX4 brain expressed, X-linked 4 0.00812571
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.00791719
MZB1 marginal zone B and B1 cell-specific protein 0.00783717
LDOC1 leucine zipper, down-regulated in cancer 1 0.00775633
CLU clusterin 0.00761741
ANXA1 annexin A1 0.00748888
KRT7 keratin 7, type II 0.00748724
SCGB2A1 secretoglobin, family 2A, member 1 0.00748196
BASP1 brain abundant, membrane attached signal protein 1 0.00747793
TXNL4A thioredoxin-like 4A 0.00728966
CST7 cystatin F (leukocystatin) 0.00725253
HK2 hexokinase 2 0.00715331
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00710455
PAX5 paired box 5 0.00705325
SMAD7 SMAD family member 7 0.00704606
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00699736
BLNK B-cell linker 0.00699374
CD52 CD52 molecule 0.00682824
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00678902
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00678869
WBP5 WW domain binding protein 5 0.00677046
MPO myeloperoxidase 0.00676988
HOPX HOP homeobox 0.00676683
FKBP11 FK506 binding protein 11, 19 kDa 0.00672305
MMP12 matrix metallopeptidase 12 0.00669784
TXNL1 thioredoxin-like 1 0.0066141
MBD2 methyl-CpG binding domain protein 2 0.00661373
METRN meteorin, glial cell differentiation regulator 0.00659027
CKS2 CDC28 protein kinase regulatory subunit 2 0.00658489
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00655762
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00653666
SOD2 superoxide dismutase 2, mitochondrial 0.00650625
TSPAN13 tetraspanin 13 0.00649271
VPREB3 pre-B lymphocyte 3 0.00648822
CKAP4 cytoskeleton-associated protein 4 0.00648502
SRGN serglycin 0.00645433
MXRA7 matrix-remodelling associated 7 0.00641242
KRT5 keratin 5, type II 0.00640351
TPSAB1 tryptase alpha/beta 1 0.00639912
CD9 CD9 molecule 0.00635403
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00634465
PNMA8A PNMA family member 8A 0.00632835
BAD BCL2-associated agonist of cell death 0.00632562
DCLK1 doublecortin-like kinase 1 0.00631475
KRT15 keratin 15, type I 0.00631457
CD79B CD79b molecule, immunoglobulin-associated beta 0.00625454
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00624395
NPEPL1 aminopeptidase-like 1 0.00622602
NXN nucleoredoxin 0.00619164
KLF5 Kruppel-like factor 5 (intestinal) 0.00616725
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00613246
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00612977
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00608191
AUTS2 autism susceptibility candidate 2 0.00607167
DGKZ diacylglycerol kinase, zeta 0.00605772
MTCL1 microtubule crosslinking factor 1 0.00604306
HIRA histone cell cycle regulator 0.00602205
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00601141
VIM vimentin 0.00599802
ELANE elastase, neutrophil expressed 0.00599052
RND3 Rho family GTPase 3 0.00598585
KDSR 3-ketodihydrosphingosine reductase 0.00598347
LOXL1 lysyl oxidase-like 1 0.00598119
EHF ets homologous factor 0.00595434
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00595177
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.0059331
RAD23B RAD23 homolog B (S. cerevisiae) 0.00591859
CCL5 chemokine (C-C motif) ligand 5 0.00590432
KDM5D lysine (K)-specific demethylase 5D 0.00589145
ACTN1 actinin, alpha 1 0.00586677
HTRA1 HtrA serine peptidase 1 0.00584521
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00584372
FST follistatin 0.0058195
GAS1 growth arrest-specific 1 0.00581251
AHSP alpha hemoglobin stabilizing protein 0.00580344
CXCL10 chemokine (C-X-C motif) ligand 10 0.0057743
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00575785
PLBD1 phospholipase B domain containing 1 0.00574439
MSMO1 methylsterol monooxygenase 1 0.00573888
PEG10 paternally expressed 10 0.00573674
TPD52L1 tumor protein D52-like 1 0.00572721
CAMP cathelicidin antimicrobial peptide 0.00571716
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00571194
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00570419
MIR22HG MIR22 host gene 0.00569051
NVL nuclear VCP-like 0.00568793
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.005674
TFPI2 tissue factor pathway inhibitor 2 0.0056251
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00562392
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00556622
CPA3 carboxypeptidase A3 (mast cell) 0.00554939
FTH1 ferritin, heavy polypeptide 1 0.00554122
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00552216
TRIM16 tripartite motif containing 16 0.00551883
GBP1 guanylate binding protein 1, interferon-inducible 0.00551742
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00551528
CTSG cathepsin G 0.00550637
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00550187
RFTN1 raftlin, lipid raft linker 1 0.00549899
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.00546668
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00543945
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00543358
CHKB choline kinase beta 0.00541901
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00541327
CYBB cytochrome b-245, beta polypeptide 0.00540209
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00540192
TCL1A T-cell leukemia/lymphoma 1A 0.00540086
PDE10A phosphodiesterase 10A 0.00537213
TPM2 tropomyosin 2 (beta) 0.00537136
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00533572
CD19 CD19 molecule 0.00533522
VEGFC vascular endothelial growth factor C 0.00532709
CDKN2AIP CDKN2A interacting protein 0.00531316
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.00528731
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00528213
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00527808
CLDN4 claudin 4 0.00526003
KRT13 keratin 13, type I 0.00525548
PITX1 paired-like homeodomain 1 0.00523402
PLA2G2D phospholipase A2, group IID 0.0052339
TACSTD2 tumor-associated calcium signal transducer 2 0.00522463
IDO1 indoleamine 2,3-dioxygenase 1 0.00520201
FAM46C family with sequence similarity 46, member C 0.00520073
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00518359
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00517842
TLE5 TLE family member 5, transcriptional modulator 0.00517258
CNN3 calponin 3, acidic 0.00514692
SIK1 salt-inducible kinase 1 0.00511021
PDLIM3 PDZ and LIM domain 3 0.0050985
GPNMB glycoprotein (transmembrane) nmb 0.00508105
LRRC15 leucine rich repeat containing 15 0.0050711
CD177 CD177 molecule 0.00505661
RAP1GAP2 RAP1 GTPase activating protein 2 0.00505457
CD8A CD8a molecule 0.00504729
NARS1 asparaginyl-tRNA synthetase 1 0.00503429
RNF6 ring finger protein (C3H2C3 type) 6 0.00503354
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0050278
JMJD6 jumonji domain containing 6 0.00502343
CTNND1 catenin (cadherin-associated protein), delta 1 0.00501093
KRT16 keratin 16, type I 0.0050105
WTAP Wilms tumor 1 associated protein 0.00497027
ZNF329 zinc finger protein 329 0.00496468
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00495275
NPY neuropeptide Y 0.00494269
PFN2 profilin 2 0.00494201
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00494069
CXCL11 chemokine (C-X-C motif) ligand 11 0.00492257
SLPI secretory leukocyte peptidase inhibitor 0.00491455
CD22 CD22 molecule 0.0049118
PLAAT3 phospholipase A and acyltransferase 3 0.00490101
GLOD4 glyoxalase domain containing 4 0.0049009
PERP PERP, TP53 apoptosis effector 0.00489657
MALL mal, T-cell differentiation protein-like 0.0048946
FAM162A family with sequence similarity 162, member A 0.00488892
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00486859
HAUS3 HAUS augmin-like complex, subunit 3 0.00486355
ATP5MJ ATP synthase membrane subunit j 0.00483272
MB myoglobin 0.00483123
WARS1 tryptophanyl-tRNA synthetase 1 0.00480258
SOX9 SRY (sex determining region Y)-box 9 0.00480206
REXO2 RNA exonuclease 2 0.00479857
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00479564
TOP1 topoisomerase (DNA) I 0.00479439
GJA1 gap junction protein, alpha 1, 43kDa 0.00479397
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00479363
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 0.00477699
STC2 stanniocalcin 2 0.00475864
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00475159
CLDN7 claudin 7 0.00474812
SCPEP1 serine carboxypeptidase 1 0.00474291
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00473899
SELENOT selenoprotein T 0.00472853
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 0.0047159
KRT8 keratin 8, type II 0.00471321
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00470493
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00469956
RABL6 RAB, member RAS oncogene family-like 6 0.004699
CLC Charcot-Leyden crystal galectin 0.00468327
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00467443
SOX11 SRY (sex determining region Y)-box 11 0.00467123
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00466039
EPHA2 EPH receptor A2 0.00464629
TMEM70 transmembrane protein 70 0.00464556
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.0046341
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.004617
DPYSL3 dihydropyrimidinase-like 3 0.0046166
ZSCAN18 zinc finger and SCAN domain containing 18 0.00461143
CYTL1 cytokine-like 1 0.00460026
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 0.00459991
PXDN peroxidasin 0.00458659
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00458377
GZMK granzyme K (granzyme 3; tryptase II) 0.00456988
KLF1 Kruppel-like factor 1 (erythroid) 0.00456705
DCN decorin 0.00456559
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00456164
CYB5A cytochrome b5 type A (microsomal) 0.00455661
TSPO translocator protein (18kDa) 0.00454292
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00453708
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00451759
CLINT1 clathrin interactor 1 0.00449839
SNRPG small nuclear ribonucleoprotein polypeptide G 0.0044971
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00448963
STRN3 striatin, calmodulin binding protein 3 0.00448074
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00446925
AZU1 azurocidin 1 0.00446836
CRYM crystallin, mu 0.00446548
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00444083
PHACTR2 phosphatase and actin regulator 2 0.00443421
CRCT1 cysteine-rich C-terminal 1 0.00443072
KRT14 keratin 14, type I 0.0044281
DUSP2 dual specificity phosphatase 2 0.00441115
MGAM maltase-glucoamylase 0.00440271
ZDHHC13 zinc finger, DHHC-type containing 13 0.00439469
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 0.00438607
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00438479
CRISP3 cysteine-rich secretory protein 3 0.004377
SGK1 serum/glucocorticoid regulated kinase 1 0.00437195
APOC1 apolipoprotein C-I 0.00436768

decreased expression

Symbol Name Standardized Value
RRAGA Ras-related GTP binding A -0.014696
MX1 MX dynamin-like GTPase 1 -0.0131284
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0123935
ISG15 ISG15 ubiquitin-like modifier -0.0121541
IFI44L interferon-induced protein 44-like -0.0120425
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0119836
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.0108799
IFI27 interferon, alpha-inducible protein 27 -0.0106954
IFI44 interferon-induced protein 44 -0.010465
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0103792
MX2 MX dynamin-like GTPase 2 -0.0098046
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00945468
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00944293
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00915658
RNASET2 ribonuclease T2 -0.00897749
TMEM176B transmembrane protein 176B -0.00879247
AOC1 amine oxidase, copper containing 1 -0.00873878
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00869954
PLIN2 perilipin 2 -0.00867561
SMC1A structural maintenance of chromosomes 1A -0.00861541
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00829562
GPC3 glypican 3 -0.00813544
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00813452
JPT2 Jupiter microtubule associated homolog 2 -0.00812649
IFI6 interferon, alpha-inducible protein 6 -0.00808649
TMEM176A transmembrane protein 176A -0.00794969
DEFB1 defensin, beta 1 -0.00791557
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00784837
CD93 CD93 molecule -0.00781308
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00781059
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00780578
PDZK1 PDZ domain containing 1 -0.00772508
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00767705
CEMIP cell migration inducing protein, hyaluronan binding -0.00761787
XAF1 XIAP associated factor 1 -0.00757645
TREM1 triggering receptor expressed on myeloid cells 1 -0.00757398
HOXB6 homeobox B6 -0.00752997
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00749999
IL17RB interleukin 17 receptor B -0.00735439
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00718851
TUBB2A tubulin, beta 2A class IIa -0.00715481
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00710479
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.007098
GPX2 glutathione peroxidase 2 -0.00708126
SCD5 stearoyl-CoA desaturase 5 -0.00703166
SORD sorbitol dehydrogenase -0.00702314
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00698037
CCL4 chemokine (C-C motif) ligand 4 -0.00693437
BIRC3 baculoviral IAP repeat containing 3 -0.0069325
CCL20 chemokine (C-C motif) ligand 20 -0.00689052
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00688659
C14ORF132 chromosome 14 open reading frame 132 -0.00685603
PIR pirin (iron-binding nuclear protein) -0.00677015
LAMA4 laminin, alpha 4 -0.006702
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00669641
MED1 mediator complex subunit 1 -0.00669031
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00666828
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00658781
EDNRB endothelin receptor type B -0.00657445
PCTP phosphatidylcholine transfer protein -0.00654268
TUBB2B tubulin, beta 2B class IIb -0.00652929
TXNIP thioredoxin interacting protein -0.00652023
ACKR3 atypical chemokine receptor 3 -0.00651433
MAMLD1 mastermind-like domain containing 1 -0.00645743
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00642978
ALB albumin -0.00641051
LRP4 low density lipoprotein receptor-related protein 4 -0.00640346
NEK3 NIMA-related kinase 3 -0.00638197
NBPF10 neuroblastoma breakpoint family, member 10 -0.00637098
C9ORF3 chromosome 9 open reading frame 3 -0.0063596
PLLP plasmolipin -0.00634169
PSAT1 phosphoserine aminotransferase 1 -0.00633685
TDRD7 tudor domain containing 7 -0.00633415
CFI complement factor I -0.00631106
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00626491
GAS7 growth arrest-specific 7 -0.006237
AIM2 absent in melanoma 2 -0.00621555
EPHB2 EPH receptor B2 -0.00621356
MAGEA3 melanoma antigen family A3 -0.00618384
RGS10 regulator of G-protein signaling 10 -0.00617901
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -0.00616021
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00613566
MDK midkine (neurite growth-promoting factor 2) -0.00612052
ABHD2 abhydrolase domain containing 2 -0.00610211
AQP1 aquaporin 1 (Colton blood group) -0.00602955
ASXL2 additional sex combs like transcriptional regulator 2 -0.0060223
CPD carboxypeptidase D -0.00599689
OXA1L oxidase (cytochrome c) assembly 1-like -0.00594216
EIF3D eukaryotic translation initiation factor 3, subunit D -0.00593575
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0059303
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0059069
MATN2 matrilin 2 -0.00589179
XPO7 exportin 7 -0.00588975
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00585107
LYPD1 LY6/PLAUR domain containing 1 -0.00584258
NCF2 neutrophil cytosolic factor 2 -0.00583599
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00581663
PIPOX pipecolic acid oxidase -0.00581652
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00580981
PLAT plasminogen activator, tissue -0.00580975
OPHN1 oligophrenin 1 -0.00580323
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00580075
SNX10 sorting nexin 10 -0.00579874
CES1 carboxylesterase 1 -0.00579374
ELOVL2 ELOVL fatty acid elongase 2 -0.0057927
DMD dystrophin -0.00579019
CDC14B cell division cycle 14B -0.00577584
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00577387
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00577374
IFIH1 interferon induced with helicase C domain 1 -0.00577329
CHN2 chimerin 2 -0.00574479
CBX1 chromobox homolog 1 -0.00573503
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00573135
THBD thrombomodulin -0.00572266
ATP10B ATPase, class V, type 10B -0.00572153
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -0.00571378
GPR183 G protein-coupled receptor 183 -0.00567913
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00566856
CD86 CD86 molecule -0.0056508
AKAP12 A kinase (PRKA) anchor protein 12 -0.00564683
BRCA1 breast cancer 1, early onset -0.00564308
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00564225
HAL histidine ammonia-lyase -0.00563362
PBX3 pre-B-cell leukemia homeobox 3 -0.00561178
CD83 CD83 molecule -0.00554533
TGFBI transforming growth factor, beta-induced, 68kDa -0.00551587
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00550809
MBD1 methyl-CpG binding domain protein 1 -0.00549731
IL2RA interleukin 2 receptor, alpha -0.00549303
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00548667
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00547763
EGR3 early growth response 3 -0.00547239
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00546489
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00545258
ADCY3 adenylate cyclase 3 -0.00544035
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.00543427
HMGB3 high mobility group box 3 -0.00541058
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00540752
EXOC5 exocyst complex component 5 -0.00539502
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00537514
GSTA4 glutathione S-transferase alpha 4 -0.00536292
APOLD1 apolipoprotein L domain containing 1 -0.0053308
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00531559
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00531347
IFI16 interferon, gamma-inducible protein 16 -0.00530297
MCOLN1 mucolipin 1 -0.00527144
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -0.00527027
HP haptoglobin -0.00525929
ZBTB18 zinc finger and BTB domain containing 18 -0.00525518
SATB2 SATB homeobox 2 -0.00525337
F8 coagulation factor VIII, procoagulant component -0.00524395
C8ORF4 chromosome 8 open reading frame 4 -0.00524021
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00522642
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00518913
DIAPH2 diaphanous-related formin 2 -0.00518874
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.00518754
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00517704
USP18 ubiquitin specific peptidase 18 -0.00517211
NLGN4X neuroligin 4, X-linked -0.00516776
MAGED2 melanoma antigen family D2 -0.00515845
ADAR adenosine deaminase, RNA-specific -0.00514181
MAGEA1 melanoma antigen family A1 -0.00513953
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00513347
KIAA0226L KIAA0226-like -0.00512703
FCGBP Fc fragment of IgG binding protein -0.00512308
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.0051185
DCTN4 dynactin 4 (p62) -0.00511753
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00511273
BARD1 BRCA1 associated RING domain 1 -0.00511231
DAPK1 death-associated protein kinase 1 -0.00510546
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.005102
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -0.00509421
TKTL1 transketolase-like 1 -0.00508306
MTUS1 microtubule associated tumor suppressor 1 -0.00508038
GAB2 GRB2-associated binding protein 2 -0.00507605
CRYBG3 beta-gamma crystallin domain containing 3 -0.00506482
LAMA3 laminin, alpha 3 -0.00505586
C4BPA complement component 4 binding protein, alpha -0.00504867
FGF13 fibroblast growth factor 13 -0.00503639
BST2 bone marrow stromal cell antigen 2 -0.00503547
LAGE3 L antigen family, member 3 -0.00502729
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00501899
SAMD9 sterile alpha motif domain containing 9 -0.00501674
BAG2 BCL2-associated athanogene 2 -0.00501357
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00501148
PPARG peroxisome proliferator-activated receptor gamma -0.00500915
LPAR6 lysophosphatidic acid receptor 6 -0.0050086
COL21A1 collagen, type XXI, alpha 1 -0.00500572
DPYSL4 dihydropyrimidinase-like 4 -0.00500503
DNMBP dynamin binding protein -0.00499931
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.00498361
SNX11 sorting nexin 11 -0.00497009
PNPO pyridoxamine 5'-phosphate oxidase -0.00494862
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.00494719
TSPAN8 tetraspanin 8 -0.00493958
MYO1C myosin IC -0.00493256
AMACR alpha-methylacyl-CoA racemase -0.00493088
NREP neuronal regeneration related protein -0.00491264
MAGEA12 melanoma antigen family A12 -0.00490542
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.00488742
TTC3 tetratricopeptide repeat domain 3 -0.00488409
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.00488016
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00485875
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.00485848
TCTN2 tectonic family member 2 -0.00485737
POGLUT2 protein O-glucosyltransferase 2 -0.00484983
FABP1 fatty acid binding protein 1, liver -0.00484895
HSPA12A heat shock 70kDa protein 12A -0.00484838
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00484831
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.00481517
MGLL monoglyceride lipase -0.00480631
TUG1 taurine up-regulated 1 (non-protein coding) -0.00480585
AK4 adenylate kinase 4 -0.00480316
STXBP6 syntaxin binding protein 6 (amisyn) -0.00480302
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00479039
NBR1 neighbor of BRCA1 gene 1 -0.00478156
PQBP1 polyglutamine binding protein 1 -0.00477785
AGTR1 angiotensin II receptor, type 1 -0.00476816
IGFBP4 insulin-like growth factor binding protein 4 -0.00476322
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -0.00475824
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00474811
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00473601
AGA aspartylglucosaminidase -0.00471749
PROM1 prominin 1 -0.00471685
RTP4 receptor (chemosensory) transporter protein 4 -0.00470194
CD99 CD99 molecule -0.00469987
GBAP1 glucosidase, beta, acid pseudogene 1 -0.004685
MYD88 myeloid differentiation primary response 88 -0.00467797
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.00466899
SOX13 SRY (sex determining region Y)-box 13 -0.00466645
ANO1 anoctamin 1, calcium activated chloride channel -0.00465909
VSIG4 V-set and immunoglobulin domain containing 4 -0.0046561
EGR2 early growth response 2 -0.00463671
WASF2 WAS protein family, member 2 -0.0046286
ADAP2 ArfGAP with dual PH domains 2 -0.00462801
NOTCH2NL notch 2 N-terminal like -0.00461762
JAK1 Janus kinase 1 -0.00461653
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00461263
F3 coagulation factor III (thromboplastin, tissue factor) -0.00460865
DENND4C DENN/MADD domain containing 4C -0.00460225
AHNAK AHNAK nucleoprotein -0.00460045
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -0.00459715
PDZD2 PDZ domain containing 2 -0.00459546
CALCOCO2 calcium binding and coiled-coil domain 2 -0.00459535
SNAP25 synaptosomal-associated protein, 25kDa -0.00459097
HOXD1 homeobox D1 -0.00458923
SPP1 secreted phosphoprotein 1 -0.00458727
EMP2 epithelial membrane protein 2 -0.00457261
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -0.00457014