KLF5 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description Kruppel-like factor 5 (intestinal)|This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] (NCBI Entrez Gene Database, 688)
External Link http://www.ncbi.nlm.nih.gov/gene/688
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Genes

67 interacting proteins for KLF5 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
BUB3 BUB3 mitotic checkpoint protein
C1ORF116 chromosome 1 open reading frame 116
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CREBBP CREB binding protein
CSNK1D casein kinase 1, delta
DCAF7 DDB1 and CUL4 associated factor 7
DGKA diacylglycerol kinase, alpha 80kDa
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DOCK9 dedicator of cytokinesis 9
ELAVL1 ELAV like RNA binding protein 1
EP300 E1A binding protein p300
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERBB2IP erbb2 interacting protein
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GSK3B glycogen synthase kinase 3 beta
GTF2B general transcription factor IIB
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HSPA1B heat shock 70kDa protein 1B
ITGB4 integrin, beta 4
LEMD3 LEM domain containing 3
MFN2 mitofusin 2
MTCH1 mitochondrial carrier 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OPA1 optic atrophy 1 (autosomal dominant)
PCID2 PCI domain containing 2
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PSPC1 paraspeckle component 1
RARA retinoic acid receptor, alpha
RIN1 Ras and Rab interactor 1
RRBP1 ribosome binding protein 1
SACK1G scaffolding CK1 anchoring protein G
SET SET nuclear proto-oncogene
SIK3 SIK family kinase 3
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNW1 SNW domain containing 1
SQRDL sulfide quinone reductase-like (yeast)
TBP TATA box binding protein
TRIM25 tripartite motif containing 25
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
WRNIP1 Werner helicase interacting protein 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
WWTR1 WW domain containing transcription regulator 1
YAP1 Yes-associated protein 1
YY1 YY1 transcription factor
ZBTB17 zinc finger and BTB domain containing 17
ZFYVE9 zinc finger, FYVE domain containing 9