| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.50_UP.V1_UP |
| Similar Terms | |
| Downloads & Tools |
96 genes differentially expressed following the KRAS.50_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ANGPTL4 | angiopoietin-like 4 |
| CALB1 | calbindin 1, 28kDa |
| CD1A | CD1a molecule |
| CDR1 | cerebellar degeneration-related protein 1, 34kDa |
| CFHR2 | complement factor H-related 2 |
| CHGB | chromogranin B |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DOCK4 | dedicator of cytokinesis 4 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ETV1 | ets variant 1 |
| ETV5 | ets variant 5 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM155B | family with sequence similarity 155, member B |
| FGF9 | fibroblast growth factor 9 |
| G0S2 | G0/G1 switch 2 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLRX | glutaredoxin (thioltransferase) |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HPN | hepsin |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| IL1RL1 | interleukin 1 receptor-like 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KIAA1549L | KIAA1549-like |
| KIF5C | kinesin family member 5C |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| MMP11 | matrix metallopeptidase 11 |
| NRCAM | neuronal cell adhesion molecule |
| NTM | neurotrimin |
| PCDH8 | protocadherin 8 |
| PEG3 | paternally expressed 3 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| RBP4 | retinol binding protein 4, plasma |
| RELN | reelin |
| SCG3 | secretogranin III |
| SCG5 | secretogranin V |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNAP91 | synaptosomal-associated protein, 91kDa |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STC1 | stanniocalcin 1 |
| TERT | telomerase reverse transcriptase |
| Symbol | Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| C5AR2 | complement component 5a receptor 2 |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CDH16 | cadherin 16, KSP-cadherin |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CRYGD | crystallin, gamma D |
| EPHB6 | EPH receptor B6 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IFI44L | interferon-induced protein 44-like |
| IGF2-AS | IGF2 antisense RNA |
| KIF25 | kinesin family member 25 |
| KRT13 | keratin 13, type I |
| KRT16 | keratin 16, type I |
| KRT38 | keratin 38, type I |
| KRT4 | keratin 4, type II |
| LOC440895 | two pore channel 3 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MX2 | MX dynamin-like GTPase 2 |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NTF3 | neurotrophin 3 |
| OLFML2A | olfactomedin-like 2A |
| PCDHB1 | protocadherin beta 1 |
| PLBD1 | phospholipase B domain containing 1 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RRAD | Ras-related associated with diabetes |
| S100A7 | S100 calcium binding protein A7 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SDS | serine dehydratase |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SOX11 | SRY (sex determining region Y)-box 11 |
| SPRR1B | small proline-rich protein 1B |
| SPRR3 | small proline-rich protein 3 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TGM1 | transglutaminase 1 |
| THRB | thyroid hormone receptor, beta |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBAL3 | tubulin, alpha-like 3 |
