KRAS.50_UP.V1 Gene Set

Dataset MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations
Category transcriptomics
Type gene perturbation
Description gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database)
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96 genes differentially expressed following the KRAS.50_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ADAM8 ADAM metallopeptidase domain 8
ANGPTL4 angiopoietin-like 4
CALB1 calbindin 1, 28kDa
CD1A CD1a molecule
CDR1 cerebellar degeneration-related protein 1, 34kDa
CFHR2 complement factor H-related 2
CHGB chromogranin B
CXCL5 chemokine (C-X-C motif) ligand 5
DHRS9 dehydrogenase/reductase (SDR family) member 9
DOCK4 dedicator of cytokinesis 4
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ETV1 ets variant 1
ETV5 ets variant 5
FABP3 fatty acid binding protein 3, muscle and heart
FAM155B family with sequence similarity 155, member B
FGF9 fibroblast growth factor 9
G0S2 G0/G1 switch 2
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HPN hepsin
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL13RA2 interleukin 13 receptor, alpha 2
IL1RL1 interleukin 1 receptor-like 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIAA1549L KIAA1549-like
KIF5C kinesin family member 5C
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMO3 LIM domain only 3 (rhombotin-like 2)
MMP11 matrix metallopeptidase 11
NRCAM neuronal cell adhesion molecule
NTM neurotrimin
PCDH8 protocadherin 8
PEG3 paternally expressed 3
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RBP4 retinol binding protein 4, plasma
RELN reelin
SCG3 secretogranin III
SCG5 secretogranin V
SIGLEC15 sialic acid binding Ig-like lectin 15
SNAP25 synaptosomal-associated protein, 25kDa
SNAP91 synaptosomal-associated protein, 91kDa
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STC1 stanniocalcin 1
TERT telomerase reverse transcriptase

decreased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACKR3 atypical chemokine receptor 3
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
C5AR2 complement component 5a receptor 2
CCR8 chemokine (C-C motif) receptor 8
CDH16 cadherin 16, KSP-cadherin
CGREF1 cell growth regulator with EF-hand domain 1
CRYGD crystallin, gamma D
EPHB6 EPH receptor B6
EPHX2 epoxide hydrolase 2, cytoplasmic
GADD45G growth arrest and DNA-damage-inducible, gamma
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HYAL4 hyaluronoglucosaminidase 4
IFI44L interferon-induced protein 44-like
IGF2-AS IGF2 antisense RNA
KIF25 kinesin family member 25
KRT13 keratin 13, type I
KRT16 keratin 16, type I
KRT38 keratin 38, type I
KRT4 keratin 4, type II
LOC440895 two pore channel 3 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MX2 MX dynamin-like GTPase 2
NCR3 natural cytotoxicity triggering receptor 3
NOS1 nitric oxide synthase 1 (neuronal)
NTF3 neurotrophin 3
OLFML2A olfactomedin-like 2A
PCDHB1 protocadherin beta 1
PLBD1 phospholipase B domain containing 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYHIN1 pyrin and HIN domain family, member 1
RRAD Ras-related associated with diabetes
S100A7 S100 calcium binding protein A7
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDS serine dehydratase
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SOX11 SRY (sex determining region Y)-box 11
SPRR1B small proline-rich protein 1B
SPRR3 small proline-rich protein 3
TAS2R4 taste receptor, type 2, member 4
TGM1 transglutaminase 1
THRB thyroid hormone receptor, beta
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TUBAL3 tubulin, alpha-like 3