| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG.BREAST_UP.V1_UP |
| Similar Terms | |
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285 genes differentially expressed following the KRAS.LUNG.BREAST_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| AMELY | amelogenin, Y-linked |
| ANGPTL4 | angiopoietin-like 4 |
| ATG10 | autophagy related 10 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP6 | bone morphogenetic protein 6 |
| CALB1 | calbindin 1, 28kDa |
| CATR1 | CATR tumorigenicity conversion 1 |
| CCDC181 | coiled-coil domain containing 181 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCR6 | chemokine (C-C motif) receptor 6 |
| CD1A | CD1a molecule |
| CD247 | CD247 molecule |
| CD37 | CD37 molecule |
| CDSN | corneodesmosin |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLPS | colipase, pancreatic |
| CLSTN2 | calsyntenin 2 |
| CMKLR1 | chemerin chemokine-like receptor 1 |
| CRCT1 | cysteine-rich C-terminal 1 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CSF3 | colony stimulating factor 3 (granulocyte) |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAH9 | dynein, axonemal, heavy chain 9 |
| DOCK4 | dedicator of cytokinesis 4 |
| ESM1 | endothelial cell-specific molecule 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FAM155B | family with sequence similarity 155, member B |
| FAM174B | family with sequence similarity 174, member B |
| FCRL2 | Fc receptor-like 2 |
| FNDC8 | fibronectin type III domain containing 8 |
| G0S2 | G0/G1 switch 2 |
| GABRA3 | gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) |
| GFI1 | growth factor independent 1 transcription repressor |
| GLRX | glutaredoxin (thioltransferase) |
| GPR4 | G protein-coupled receptor 4 |
| GRP | gastrin-releasing peptide |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| GYPC | glycophorin C (Gerbich blood group) |
| HAS2 | hyaluronan synthase 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HOXD11 | homeobox D11 |
| HPN | hepsin |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IFNA8 | interferon, alpha 8 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGHV3-48 | immunoglobulin heavy variable 3-48 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RL1 | interleukin 1 receptor-like 1 |
| IL23A | interleukin 23, alpha subunit p19 |
| IL37 | interleukin 37 |
| INHBA | inhibin, beta A |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNC2 | potassium channel, voltage gated Shaw related subfamily C, member 2 |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIAA1549L | KIAA1549-like |
| KIF5A | kinesin family member 5A |
| KIF5C | kinesin family member 5C |
| KRT34 | keratin 34, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LDB3 | LIM domain binding 3 |
| LIF | leukemia inhibitory factor |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| MGLL | monoglyceride lipase |
| MKRN3 | makorin ring finger protein 3 |
| MMP1 | matrix metallopeptidase 1 |
| MMP10 | matrix metallopeptidase 10 |
| MMP9 | matrix metallopeptidase 9 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| NAV3 | neuron navigator 3 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NELL2 | NEL-like 2 (chicken) |
| NPPB | natriuretic peptide B |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NRL | neural retina leucine zipper |
| NTM | neurotrimin |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSBP2 | oxysterol binding protein 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PDCD1LG2 | programmed cell death 1 ligand 2 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| POLM | polymerase (DNA directed), mu |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRL | prolactin |
| PRSS3 | protease, serine, 3 |
| PRY | PTPN13-like, Y-linked |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RBMXL2 | RNA binding motif protein, X-linked-like 2 |
| RBP4 | retinol binding protein 4, plasma |
| RELN | reelin |
| RETN | resistin |
| RMST | rhabdomyosarcoma 2 associated transcript (non-protein coding) |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCG5 | secretogranin V |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SH2D2A | SH2 domain containing 2A |
| SHOX | short stature homeobox |
| SLC25A31 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SMPX | small muscle protein, X-linked |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNAP91 | synaptosomal-associated protein, 91kDa |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STC1 | stanniocalcin 1 |
| TAAR5 | trace amine associated receptor 5 |
| TAGLN3 | transgelin 3 |
| TBX3 | T-box 3 |
| TERT | telomerase reverse transcriptase |
| TFDP3 | transcription factor Dp family, member 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRAF1 | TNF receptor-associated factor 1 |
| TSPAN1 | tetraspanin 1 |
| TSPY1 | testis specific protein, Y-linked 1 |
| TTC22 | tetratricopeptide repeat domain 22 |
| ZNF639 | zinc finger protein 639 |
| ZP4 | zona pellucida glycoprotein 4 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ADD2 | adducin 2 (beta) |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ALOX12B | arachidonate 12-lipoxygenase, 12R type |
| AMBN | ameloblastin (enamel matrix protein) |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APOB | apolipoprotein B |
| ART1 | ADP-ribosyltransferase 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BDKRB1 | bradykinin receptor B1 |
| C5AR2 | complement component 5a receptor 2 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CALCB | calcitonin-related polypeptide beta |
| CALML3 | calmodulin-like 3 |
| CALML5 | calmodulin-like 5 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC132 | coiled-coil domain containing 132 |
| CD248 | CD248 molecule, endosialin |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD6 | CD6 molecule |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) |
| CDH16 | cadherin 16, KSP-cadherin |
| CLCA2 | chloride channel accessory 2 |
| CLDN8 | claudin 8 |
| COBL | cordon-bleu WH2 repeat protein |
| COL2A1 | collagen, type II, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYP21A2 | cytochrome P450, family 21, subfamily A, polypeptide 2 |
| DEFB1 | defensin, beta 1 |
| DPT | dermatopontin |
| DTNB | dystrobrevin, beta |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FLT1 | fms-related tyrosine kinase 1 |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GDNF | glial cell derived neurotrophic factor |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLYAT | glycine-N-acyltransferase |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H3A | histone cluster 1, H3a |
| HRK | harakiri, BCL2 interacting protein |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI44L | interferon-induced protein 44-like |
| IFNA16 | interferon, alpha 16 |
| IGF2-AS | IGF2 antisense RNA |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL5RA | interleukin 5 receptor, alpha |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| IVL | involucrin |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KIF25 | kinesin family member 25 |
| KRT13 | keratin 13, type I |
| KRT16 | keratin 16, type I |
| KRT38 | keratin 38, type I |
| KRT4 | keratin 4, type II |
| LGALS7 | lectin, galactoside-binding, soluble, 7 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LOC100288903 | |
| LOC440895 | two pore channel 3 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEGF8 | multiple EGF-like-domains 8 |
| METTL7A | methyltransferase like 7A |
| MMP28 | matrix metallopeptidase 28 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MXD3 | MAX dimerization protein 3 |
| MXRA8 | matrix-remodelling associated 8 |
| MYL9 | myosin, light chain 9, regulatory |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NTF3 | neurotrophin 3 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OLFML2A | olfactomedin-like 2A |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCDHB1 | protocadherin beta 1 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLBD1 | phospholipase B domain containing 1 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PVALB | parvalbumin |
| RAG1 | recombination activating gene 1 |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBM17 | RNA binding motif protein 17 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RTP4 | receptor (chemosensory) transporter protein 4 |
| RUNDC3B | RUN domain containing 3B |
| RYR1 | ryanodine receptor 1 (skeletal) |
| S100A7 | S100 calcium binding protein A7 |
| SCARF1 | scavenger receptor class F, member 1 |
| SCN7A | sodium channel, voltage gated, type VII alpha subunit |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporter), member 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SOX11 | SRY (sex determining region Y)-box 11 |
| SPAG11A | sperm associated antigen 11A |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TBR1 | T-box, brain, 1 |
| TGM1 | transglutaminase 1 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNNI3 | troponin I type 3 (cardiac) |
| TRIM48 | tripartite motif containing 48 |
| TRIM9 | tripartite motif containing 9 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSHB | thyroid stimulating hormone, beta |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UPK3B | uroplakin 3B |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VAX2 | ventral anterior homeobox 2 |
| YPEL1 | yippee-like 1 (Drosophila) |
