| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/KRAS.LUNG_UP.V1_UP |
| Similar Terms | |
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281 genes differentially expressed following the KRAS.LUNG_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALLC | allantoicase |
| ANGPTL4 | angiopoietin-like 4 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATG10 | autophagy related 10 |
| AURKC | aurora kinase C |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BCL2A1 | BCL2-related protein A1 |
| BTC | betacellulin |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C3AR1 | complement component 3a receptor 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CD1A | CD1a molecule |
| CD247 | CD247 molecule |
| CD48 | CD48 molecule |
| CD80 | CD80 molecule |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CELA2B | chymotrypsin-like elastase family, member 2B |
| CFAP69 | cilia and flagella associated protein 69 |
| CLEC4A | C-type lectin domain family 4, member A |
| CLSTN3 | calsyntenin 3 |
| CRYAA | crystallin, alpha A |
| CSF3 | colony stimulating factor 3 (granulocyte) |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| CYTIP | cytohesin 1 interacting protein |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DOCK2 | dedicator of cytokinesis 2 |
| DOCK4 | dedicator of cytokinesis 4 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EVI2A | ecotropic viral integration site 2A |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO4 | F-box protein 4 |
| FNDC8 | fibronectin type III domain containing 8 |
| FRMD1 | FERM domain containing 1 |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
| G0S2 | G0/G1 switch 2 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) |
| GPR3 | G protein-coupled receptor 3 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
| GRIP2 | glutamate receptor interacting protein 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HOXD11 | homeobox D11 |
| HPN | hepsin |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFNA8 | interferon, alpha 8 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| IL1RL1 | interleukin 1 receptor-like 1 |
| IL23A | interleukin 23, alpha subunit p19 |
| INHBA | inhibin, beta A |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JAK3 | Janus kinase 3 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KIAA1549L | KIAA1549-like |
| KIF5C | kinesin family member 5C |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LAG3 | lymphocyte-activation gene 3 |
| LDB3 | LIM domain binding 3 |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAGEA6 | melanoma antigen family A6 |
| MMP1 | matrix metallopeptidase 1 |
| MMP20 | matrix metallopeptidase 20 |
| MT3 | metallothionein 3 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NAV3 | neuron navigator 3 |
| NDNF | neuron-derived neurotrophic factor |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NELL2 | NEL-like 2 (chicken) |
| NES | nestin |
| NGF | nerve growth factor (beta polypeptide) |
| NKX2-5 | NK2 homeobox 5 |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NRP1 | neuropilin 1 |
| NTM | neurotrimin |
| OGDHL | oxoglutarate dehydrogenase-like |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAX4 | paired box 4 |
| PCDH17 | protocadherin 17 |
| PDCD1LG2 | programmed cell death 1 ligand 2 |
| POLM | polymerase (DNA directed), mu |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRG3 | proteoglycan 3 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RBP4 | retinol binding protein 4, plasma |
| RELN | reelin |
| RETN | resistin |
| RGS4 | regulator of G-protein signaling 4 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCG5 | secretogranin V |
| SDCCAG8 | serologically defined colon cancer antigen 8 |
| SEMG2 | semenogelin II |
| SH2D2A | SH2 domain containing 2A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A8 | solute carrier family 16 (monocarboxylate transporter), member 8 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
| SLC6A11 | solute carrier family 6 (neurotransmitter transporter), member 11 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SMPX | small muscle protein, X-linked |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBX3 | T-box 3 |
| TEX13A | testis expressed 13A |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM176B | transmembrane protein 176B |
| TNNT2 | troponin T type 2 (cardiac) |
| TSPAN1 | tetraspanin 1 |
| TSPY1 | testis specific protein, Y-linked 1 |
| TTC22 | tetratricopeptide repeat domain 22 |
| UGT1A10 | UDP glucuronosyltransferase 1 family, polypeptide A10 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF639 | zinc finger protein 639 |
| ZNF749 | zinc finger protein 749 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACHE | acetylcholinesterase (Yt blood group) |
| ACPP | acid phosphatase, prostate |
| ADD2 | adducin 2 (beta) |
| ADORA3 | adenosine A3 receptor |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BBC3 | BCL2 binding component 3 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CACNA1F | calcium channel, voltage-dependent, L type, alpha 1F subunit |
| CALML3 | calmodulin-like 3 |
| CALML5 | calmodulin-like 5 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC132 | coiled-coil domain containing 132 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD22 | CD22 molecule |
| CD248 | CD248 molecule, endosialin |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) |
| CDH16 | cadherin 16, KSP-cadherin |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFAP74 | cilia and flagella associated protein 74 |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| CLCA4 | chloride channel accessory 4 |
| COBL | cordon-bleu WH2 repeat protein |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL2A1 | collagen, type II, alpha 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRYAB | crystallin, alpha B |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DEFB1 | defensin, beta 1 |
| DHX58 | DEXH (Asp-Glu-X-His) box polypeptide 58 |
| EMID1 | EMI domain containing 1 |
| EPHB3 | EPH receptor B3 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 |
| GALNT8 | polypeptide N-acetylgalactosaminyltransferase 8 |
| GAS1 | growth arrest-specific 1 |
| GDNF | glial cell derived neurotrophic factor |
| GLYAT | glycine-N-acyltransferase |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR45 | G protein-coupled receptor 45 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IHH | indian hedgehog |
| IL10RA | interleukin 10 receptor, alpha |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| IVL | involucrin |
| KLK11 | kallikrein-related peptidase 11 |
| KLK12 | kallikrein-related peptidase 12 |
| KLK7 | kallikrein-related peptidase 7 |
| KLK8 | kallikrein-related peptidase 8 |
| KRT1 | keratin 1, type II |
| KRT13 | keratin 13, type I |
| KRT15 | keratin 15, type I |
| KRT16 | keratin 16, type I |
| KRT4 | keratin 4, type II |
| LGALS7 | lectin, galactoside-binding, soluble, 7 |
| LMO1 | LIM domain only 1 (rhombotin 1) |
| LOC440895 | two pore channel 3 pseudogene |
| LOC57399 | uncharacterized gastric protein ZA52P |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MC5R | melanocortin 5 receptor |
| MEGF8 | multiple EGF-like-domains 8 |
| METTL7A | methyltransferase like 7A |
| MORC1 | MORC family CW-type zinc finger 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NGFR | nerve growth factor receptor |
| NPY4R | neuropeptide Y receptor Y4 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OLFML2A | olfactomedin-like 2A |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PALM | paralemmin |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLA2G10 | phospholipase A2, group X |
| PLCH2 | phospholipase C, eta 2 |
| POSTN | periostin, osteoblast specific factor |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PROM1 | prominin 1 |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAG1 | recombination activating gene 1 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RHCG | Rh family, C glycoprotein |
| RTP4 | receptor (chemosensory) transporter protein 4 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| S100A12 | S100 calcium binding protein A12 |
| S100A7 | S100 calcium binding protein A7 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCARF1 | scavenger receptor class F, member 1 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCRG1 | stimulator of chondrogenesis 1 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3BP1 | SH3-domain binding protein 1 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPRR3 | small proline-rich protein 3 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TF | transferrin |
| TGM1 | transglutaminase 1 |
| THAP9 | THAP domain containing 9 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRGV7 | T cell receptor gamma variable 7 (pseudogene) |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TRIM48 | tripartite motif containing 48 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK3B | uroplakin 3B |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VPREB1 | pre-B lymphocyte 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF750 | zinc finger protein 750 |
| ZNF862 | zinc finger protein 862 |
