KRAS Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Kirsten rat sarcoma viral oncogene homolog|This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3845)
External Link https://ncbi.nlm.nih.gov/gene/3845
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Genes

499 genes differentially expressed following the KRAS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0180988
SLC38A1 solute carrier family 38, member 1 0.0150478
MAP7 microtubule-associated protein 7 0.0148659
STK10 serine/threonine kinase 10 0.0133349
KRT14 keratin 14, type I 0.0132763
GNAS GNAS complex locus 0.0128792
HSPB8 heat shock 22kDa protein 8 0.0115839
APOD apolipoprotein D 0.0112535
PERP PERP, TP53 apoptosis effector 0.0110202
COL9A3 collagen, type IX, alpha 3 0.0108891
QPCT glutaminyl-peptide cyclotransferase 0.00929987
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00893751
SNAP25 synaptosomal-associated protein, 25kDa 0.0089309
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00881742
AQP3 aquaporin 3 (Gill blood group) 0.00871064
KANK1 KN motif and ankyrin repeat domains 1 0.00856429
HMOX1 heme oxygenase 1 0.00855461
AMOTL2 angiomotin like 2 0.00854015
HSPA1A heat shock 70kDa protein 1A 0.00835687
CRYAB crystallin, alpha B 0.00831593
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00829562
LAMB1 laminin, beta 1 0.00824388
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00816934
KRT7 keratin 7, type II 0.00811957
CIAO3 cytosolic iron-sulfur assembly component 3 0.00776447
REEP1 receptor accessory protein 1 0.00775201
PCDH9 protocadherin 9 0.00768222
TFPI2 tissue factor pathway inhibitor 2 0.00764709
S100P S100 calcium binding protein P 0.00763427
POU2AF1 POU class 2 associating factor 1 0.00760016
INAVA innate immunity activator 0.00754191
ANKRD11 ankyrin repeat domain 11 0.007366
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00734359
L1CAM L1 cell adhesion molecule 0.00716314
MGLL monoglyceride lipase 0.00714964
ASS1 argininosuccinate synthase 1 0.00710949
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00706759
TES testin LIM domain protein 0.00705884
NRCAM neuronal cell adhesion molecule 0.00701732
FGFR3 fibroblast growth factor receptor 3 0.00699391
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00697961
PXDN peroxidasin 0.00679692
UGT8 UDP glycosyltransferase 8 0.00678191
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00676671
DIPK1A divergent protein kinase domain 1A 0.00672083
PTK2B protein tyrosine kinase 2 beta 0.00669467
EGFL6 EGF-like-domain, multiple 6 0.00669433
OSBPL10 oxysterol binding protein-like 10 0.00665885
EPS8L2 EPS8-like 2 0.0066257
PXDC1 PX domain containing 1 0.00661885
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.00658092
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.00657557
HOMER3 homer scaffolding protein 3 0.00656164
CLCN7 chloride channel, voltage-sensitive 7 0.0065184
BRD4 bromodomain containing 4 0.00651074
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00648119
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.00644154
PPARG peroxisome proliferator-activated receptor gamma 0.0064121
SOX11 SRY (sex determining region Y)-box 11 0.00641192
ITGA6 integrin, alpha 6 0.00639706
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00638354
PILRB paired immunoglobin-like type 2 receptor beta 0.00635662
IFI6 interferon, alpha-inducible protein 6 0.00634942
GPR17 G protein-coupled receptor 17 0.00634564
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.0063098
PLIN2 perilipin 2 0.00628064
MET MET proto-oncogene, receptor tyrosine kinase 0.00627792
CLIP2 CAP-GLY domain containing linker protein 2 0.00627661
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00619595
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.00613551
GSDMB gasdermin B 0.00611767
CHGB chromogranin B 0.00611039
MVP major vault protein 0.00609428
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00608252
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00607983
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00607214
TRIP6 thyroid hormone receptor interactor 6 0.00606222
MX1 MX dynamin-like GTPase 1 0.00603846
HIP1R huntingtin interacting protein 1 related 0.00602222
COL9A2 collagen, type IX, alpha 2 0.00599368
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.0059882
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00597465
JAK1 Janus kinase 1 0.00595504
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00593815
CARD10 caspase recruitment domain family, member 10 0.00591975
STK26 serine/threonine protein kinase 26 0.00591683
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00589297
NUAK1 NUAK family, SNF1-like kinase, 1 0.00589241
SAMD4A sterile alpha motif domain containing 4A 0.00589071
RGS5 regulator of G-protein signaling 5 0.00588598
WDR45 WD repeat domain 45 0.00587946
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00586901
COL16A1 collagen, type XVI, alpha 1 0.00586257
EIF6 eukaryotic translation initiation factor 6 0.00580855
PDZK1 PDZ domain containing 1 0.00580665
SCGB2A2 secretoglobin, family 2A, member 2 0.00578623
CLCN4 chloride channel, voltage-sensitive 4 0.0057585
ARHGAP45 Rho GTPase activating protein 45 0.00574937
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00572413
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.00571722
RFTN1 raftlin, lipid raft linker 1 0.00571303
PEG10 paternally expressed 10 0.00569568
YPEL5 yippee-like 5 (Drosophila) 0.00568827
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00566736
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00564388
SCGB1D2 secretoglobin, family 1D, member 2 0.0056376
IFRD1 interferon-related developmental regulator 1 0.00562732
TRIM29 tripartite motif containing 29 0.00560761
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00557119
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00555788
SMAD7 SMAD family member 7 0.0055482
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0055468
KDM5A lysine (K)-specific demethylase 5A 0.00554531
ZBTB38 zinc finger and BTB domain containing 38 0.00553549
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00553099
CST1 cystatin SN 0.00551572
USP47 ubiquitin specific peptidase 47 0.0055103
DSP desmoplakin 0.00548419
GOLGA8A golgin A8 family, member A 0.00548338
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.005483
ACAN aggrecan 0.00546001
NOTCH1 notch 1 0.00544422
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.00544297
MB myoglobin 0.0054186
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00539472
ECM1 extracellular matrix protein 1 0.00538522
EHD3 EH-domain containing 3 0.00537572
ELF4 E74-like factor 4 (ets domain transcription factor) 0.00537043
GAL3ST1 galactose-3-O-sulfotransferase 1 0.00536469
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0053527
TMC6 transmembrane channel-like 6 0.00534606
CCND2 cyclin D2 0.0053388
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00533869
NVL nuclear VCP-like 0.00532875
FILIP1L filamin A interacting protein 1-like 0.00532121
SYNM synemin, intermediate filament protein 0.00531706
CLIC3 chloride intracellular channel 3 0.00531662
POU4F1 POU class 4 homeobox 1 0.00531628
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00531524
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 0.00527239
PLAAT3 phospholipase A and acyltransferase 3 0.00525583
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.00525441
ITM2C integral membrane protein 2C 0.00525193
PTN pleiotrophin 0.00525164
TUBB2B tubulin, beta 2B class IIb 0.00524643
MID1 midline 1 0.005246
ZNF395 zinc finger protein 395 0.0052398
XYLT1 xylosyltransferase I 0.00523374
CA10 carbonic anhydrase X 0.00522984
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00521114
TTC39A tetratricopeptide repeat domain 39A 0.00521076
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00520785
WARS1 tryptophanyl-tRNA synthetase 1 0.00520455
PLXNB2 plexin B2 0.00520371
NKX2-2 NK2 homeobox 2 0.00520261
LONP1 lon peptidase 1, mitochondrial 0.00519394
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.00518472
COL14A1 collagen, type XIV, alpha 1 0.00517008
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00516031
CYB5R2 cytochrome b5 reductase 2 0.0051587
ALOX5 arachidonate 5-lipoxygenase 0.00514032
PIP prolactin-induced protein 0.00513156
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.00512952
COBL cordon-bleu WH2 repeat protein 0.00510605
SPATA20 spermatogenesis associated 20 0.00510588
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00510226
GPNMB glycoprotein (transmembrane) nmb 0.00510189
RRAGA Ras-related GTP binding A 0.00508831
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00507546
LIMK2 LIM domain kinase 2 0.00504658
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.00504376
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00504278
DCX doublecortin 0.00504187
PARP12 poly (ADP-ribose) polymerase family, member 12 0.00502976
TRAF5 TNF receptor-associated factor 5 0.00502941
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0050233
RGS16 regulator of G-protein signaling 16 0.00501491
TGFB3 transforming growth factor, beta 3 0.0050101
AUTS2 autism susceptibility candidate 2 0.00499816
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00498894
FAM110B family with sequence similarity 110, member B 0.00498787
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.0049865
MYH9 myosin, heavy chain 9, non-muscle 0.0049798
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00497591
NUSAP1 nucleolar and spindle associated protein 1 0.00497157
PLXND1 plexin D1 0.00497106
ADGRG2 adhesion G protein-coupled receptor G2 0.00496421
ATF3 activating transcription factor 3 0.00493701
NEBL nebulette 0.00493664
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00492441
STK32B serine/threonine kinase 32B 0.00490823
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00488657
ZSWIM8 zinc finger, SWIM-type containing 8 0.00487593
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.00487037
ANGPT2 angiopoietin 2 0.00486911
MINK1 misshapen-like kinase 1 0.00486671
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00486317
INHBA inhibin, beta A 0.0048622
KLF5 Kruppel-like factor 5 (intestinal) 0.00485884
ITSN2 intersectin 2 0.00485082
ZNF91 zinc finger protein 91 0.00483398
BCAS1 breast carcinoma amplified sequence 1 0.0048009
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.0047922
GJA1 gap junction protein, alpha 1, 43kDa 0.00478801
KLK5 kallikrein-related peptidase 5 0.00478463
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00477749
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.00477245
TMCC1 transmembrane and coiled-coil domain family 1 0.00476564
BLNK B-cell linker 0.00476523
STMN2 stathmin 2 0.00476477
NEFH neurofilament, heavy polypeptide 0.00476052
TPSAB1 tryptase alpha/beta 1 0.00474426
FN1 fibronectin 1 0.00473787
MICALL2 MICAL-like 2 0.00472041
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00471644
STK38 serine/threonine kinase 38 0.00471578
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00471429
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00470982
CDV3 CDV3 homolog (mouse) 0.00470798
BMP2 bone morphogenetic protein 2 0.00470707
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00469563
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 0.00469258
NCAM1 neural cell adhesion molecule 1 0.00468685
RHOBTB3 Rho-related BTB domain containing 3 0.00468553
FXYD2 FXYD domain containing ion transport regulator 2 0.00468431
FBLN2 fibulin 2 0.00467935
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.0046742
ZHX2 zinc fingers and homeoboxes 2 0.00467183
SGK1 serum/glucocorticoid regulated kinase 1 0.00466983
TAGLN transgelin 0.00466944
NBEAL2 neurobeachin-like 2 0.00466671
NAV2 neuron navigator 2 0.0046654
SYNGR3 synaptogyrin 3 0.00466125
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00465608
RND3 Rho family GTPase 3 0.00464204
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00463569
CCND3 cyclin D3 0.00462948
MFAP3L microfibrillar-associated protein 3-like 0.00462159
TRIB3 tribbles pseudokinase 3 0.00461785
RBM34 RNA binding motif protein 34 0.00461149
HSPB1 heat shock 27kDa protein 1 0.0045983
COL2A1 collagen, type II, alpha 1 0.00459229
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.00459197
KMT2B lysine (K)-specific methyltransferase 2B 0.00458873
WASL Wiskott-Aldrich syndrome-like 0.00457268
SOX10 SRY (sex determining region Y)-box 10 0.00457004
PLXNB3 plexin B3 0.00456737
ZYX zyxin 0.00456159
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.00455615

decreased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 -0.0139771
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.01354
CDCA4 cell division cycle associated 4 -0.0113716
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0108085
DCXR dicarbonyl/L-xylulose reductase -0.00960844
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -0.0095357
TXNDC9 thioredoxin domain containing 9 -0.00900157
SSBP2 single-stranded DNA binding protein 2 -0.00883395
GCA grancalcin, EF-hand calcium binding protein -0.00864728
RPA3 replication protein A3, 14kDa -0.00859158
SFRP1 secreted frizzled-related protein 1 -0.00857719
CHEK2 checkpoint kinase 2 -0.00840874
PRPF4 pre-mRNA processing factor 4 -0.00840798
CDC20 cell division cycle 20 -0.00791604
GSTO1 glutathione S-transferase omega 1 -0.00767612
PRDX2 peroxiredoxin 2 -0.00764687
PIR pirin (iron-binding nuclear protein) -0.00760331
TYRP1 tyrosinase-related protein 1 -0.00750775
ESR1 estrogen receptor 1 -0.00748477
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00744166
CCNA2 cyclin A2 -0.00743996
COMMD10 COMM domain containing 10 -0.00733599
TMEM14A transmembrane protein 14A -0.00733351
ECI2 enoyl-CoA delta isomerase 2 -0.00731918
S100A9 S100 calcium binding protein A9 -0.0072105
PITX3 paired-like homeodomain 3 -0.00719606
WDR7 WD repeat domain 7 -0.00716281
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00700268
TFF3 trefoil factor 3 (intestinal) -0.00698465
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.0069427
COMMD8 COMM domain containing 8 -0.00690929
PI3 peptidase inhibitor 3, skin-derived -0.00687876
LRRC17 leucine rich repeat containing 17 -0.00683242
PRDX4 peroxiredoxin 4 -0.00682362
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00674256
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00667127
DPYD dihydropyrimidine dehydrogenase -0.00666919
LY86 lymphocyte antigen 86 -0.00662289
TMEM14B transmembrane protein 14B -0.0065966
LIPT1 lipoyltransferase 1 -0.00657374
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00651045
LSM1 LSM1, U6 small nuclear RNA associated -0.00649792
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00641071
PLPBP pyridoxal phosphate binding protein -0.00635241
SACS sacsin molecular chaperone -0.00634681
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.006322
CTSH cathepsin H -0.00631246
FXYD3 FXYD domain containing ion transport regulator 3 -0.00630895
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00630453
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00627115
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -0.00626953
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00626393
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.0062317
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00620521
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00620151
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00619188
ANXA5 annexin A5 -0.00618111
TYR tyrosinase -0.00611033
POLB polymerase (DNA directed), beta -0.00606702
AK4 adenylate kinase 4 -0.00602394
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00602263
PMEL premelanosome protein -0.00602119
ENO2 enolase 2 (gamma, neuronal) -0.00600847
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00597585
LAPTM4B lysosomal protein transmembrane 4 beta -0.00596765
RPS5 ribosomal protein S5 -0.00594709
AKAP7 A kinase (PRKA) anchor protein 7 -0.00593225
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00590755
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00590736
PDCD10 programmed cell death 10 -0.00590245
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00588879
SIVA1 SIVA1, apoptosis-inducing factor -0.00587167
CST3 cystatin C -0.00587165
TREM1 triggering receptor expressed on myeloid cells 1 -0.00585738
ATP5PD ATP synthase peripheral stalk subunit d -0.00582695
ATG5 autophagy related 5 -0.00581811
DCK deoxycytidine kinase -0.00581611
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00581419
RANBP1 RAN binding protein 1 -0.00580278
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.00580255
MRPL48 mitochondrial ribosomal protein L48 -0.005793
BCL2A1 BCL2-related protein A1 -0.00579252
MT1E metallothionein 1E -0.00578137
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00575559
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00575049
DLK1 delta-like 1 homolog (Drosophila) -0.00572432
BAG2 BCL2-associated athanogene 2 -0.00572022
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00570519
PGC progastricsin (pepsinogen C) -0.00569792
GUCY2C guanylate cyclase 2C -0.00568008
ATP5F1C ATP synthase F1 subunit gamma -0.00566232
SEPP1 selenoprotein P, plasma, 1 -0.00562011
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.0056096
F2R coagulation factor II (thrombin) receptor -0.00559547
LAGE3 L antigen family, member 3 -0.00553887
WDR61 WD repeat domain 61 -0.00552801
RHOA ras homolog family member A -0.0055195
COPS4 COP9 signalosome subunit 4 -0.00550588
RFK riboflavin kinase -0.00549892
HLA-F-AS1 HLA-F antisense RNA 1 -0.00549749
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00546482
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00545993
RNASEH2A ribonuclease H2, subunit A -0.00545154
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00543829
DYNLT1 dynein, light chain, Tctex-type 1 -0.00542735
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -0.00542067
IDE insulin-degrading enzyme -0.00541884
PPA2 pyrophosphatase (inorganic) 2 -0.00540746
ERLIN2 ER lipid raft associated 2 -0.00540505
PEX2 peroxisomal biogenesis factor 2 -0.00540468
ESD esterase D -0.00538772
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00538547
IER3IP1 immediate early response 3 interacting protein 1 -0.00537087
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00537042
CGRRF1 cell growth regulator with ring finger domain 1 -0.00534326
SKP1 S-phase kinase-associated protein 1 -0.00532519
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -0.00532057
SELENBP1 selenium binding protein 1 -0.00530683
ARL3 ADP-ribosylation factor-like 3 -0.00529876
SPTSSA serine palmitoyltransferase, small subunit A -0.00529804
PRDX6 peroxiredoxin 6 -0.00528925
EGR3 early growth response 3 -0.00528811
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00526062
CAPZB capping protein (actin filament) muscle Z-line, beta -0.00526011
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00525201
GCK glucokinase (hexokinase 4) -0.00524006
HAL histidine ammonia-lyase -0.00523633
ANAPC15 anaphase promoting complex subunit 15 -0.00523204
IFT52 intraflagellar transport 52 -0.00522678
ADGRE1 adhesion G protein-coupled receptor E1 -0.00520859
TSPAN6 tetraspanin 6 -0.00520381
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.00519653
CENPX centromere protein X -0.00519587
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.00518828
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.0051849
CPVL carboxypeptidase, vitellogenic-like -0.00518332
RGS10 regulator of G-protein signaling 10 -0.0051831
IQCG IQ motif containing G -0.00517216
VRK1 vaccinia related kinase 1 -0.00516227
ADAM9 ADAM metallopeptidase domain 9 -0.0051616
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0051604
NTS neurotensin -0.00515491
CTSB cathepsin B -0.00514403
ANG angiogenin, ribonuclease, RNase A family, 5 -0.00514157
PLAUR plasminogen activator, urokinase receptor -0.00513925
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00512977
SAP30 Sin3A-associated protein, 30kDa -0.00512726
SEC23A Sec23 homolog A (S. cerevisiae) -0.00508853
CEL carboxyl ester lipase -0.00508579
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -0.00508333
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -0.00508156
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.00507723
B3GNT1 -0.00507371
ZNHIT3 zinc finger, HIT-type containing 3 -0.00506004
TXNL1 thioredoxin-like 1 -0.00503917
KDM5D lysine (K)-specific demethylase 5D -0.00503265
HNMT histamine N-methyltransferase -0.00502098
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -0.00502014
RMI1 RecQ mediated genome instability 1 -0.00501161
NMD3 NMD3 ribosome export adaptor -0.00501003
TDP1 tyrosyl-DNA phosphodiesterase 1 -0.00500725
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00500457
GMDS GDP-mannose 4,6-dehydratase -0.00499358
MYBPC1 myosin binding protein C, slow type -0.00499279
PFN2 profilin 2 -0.00498302
NDP Norrie disease (pseudoglioma) -0.00496563
GPR65 G protein-coupled receptor 65 -0.00496555
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -0.00496502
MOCS2 molybdenum cofactor synthesis 2 -0.00495682
ZBTB18 zinc finger and BTB domain containing 18 -0.00495379
MYH10 myosin, heavy chain 10, non-muscle -0.00495069
RFC3 replication factor C (activator 1) 3, 38kDa -0.00494557
GLRX5 glutaredoxin 5 -0.00494164
EIF4A3 eukaryotic translation initiation factor 4A3 -0.00493598
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.00492972
CD302 CD302 molecule -0.0049269
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -0.00490645
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00489928
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -0.00488522
CRYL1 crystallin, lambda 1 -0.00486437
MBIP MAP3K12 binding inhibitory protein 1 -0.00485746
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00482892
COX7B cytochrome c oxidase subunit VIIb -0.00482584
GLRX3 glutaredoxin 3 -0.00481302
ICAM3 intercellular adhesion molecule 3 -0.00480674
RPL36 ribosomal protein L36 -0.0048047
TSNAX translin-associated factor X -0.0048039
TFF1 trefoil factor 1 -0.00480246
MLPH melanophilin -0.00477925
CETN2 centrin, EF-hand protein, 2 -0.00477614
ELOB elongin B -0.00476285
MRPL42 mitochondrial ribosomal protein L42 -0.00475472
PRKCQ protein kinase C, theta -0.00475085
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00475075
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.00474593
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00473455
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -0.00472153
TPGS2 tubulin polyglutamylase complex subunit 2 -0.00470231
FBXO11 F-box protein 11 -0.00468659
PFDN5 prefoldin subunit 5 -0.004684
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00468147
BLVRB biliverdin reductase B -0.00467242
CRYZ crystallin, zeta (quinone reductase) -0.00466215
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.00466184
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0046608
TMEM126B transmembrane protein 126B -0.00461347
NXT1 nuclear transport factor 2-like export factor 1 -0.00460618
RPL29 ribosomal protein L29 -0.00459951
POPDC3 popeye domain containing 3 -0.00459659
BIRC5 baculoviral IAP repeat containing 5 -0.00458907
PAQR3 progestin and adipoQ receptor family member III -0.0045788
DMAC2L distal membrane arm assembly component 2 like -0.00456551
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00456395
RSL1D1 ribosomal L1 domain containing 1 -0.00455039
MED7 mediator complex subunit 7 -0.0045458
ANXA10 annexin A10 -0.0045311
DCTN3 dynactin 3 (p22) -0.00452242
TOB1 transducer of ERBB2, 1 -0.00452153
BAG4 BCL2-associated athanogene 4 -0.00451851
FECH ferrochelatase -0.00451805
ZNF516 zinc finger protein 516 -0.00451788
JPT2 Jupiter microtubule associated homolog 2 -0.00451344
MRPL17 mitochondrial ribosomal protein L17 -0.00451328
FMO5 flavin containing monooxygenase 5 -0.00451169
SSR1 signal sequence receptor, alpha -0.00450762
FZD6 frizzled class receptor 6 -0.00450474
GEMIN2 gem (nuclear organelle) associated protein 2 -0.00450175
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00448779
ARMT1 acidic residue methyltransferase 1 -0.00448444
GCH1 GTP cyclohydrolase 1 -0.0044818
RPP30 ribonuclease P/MRP 30kDa subunit -0.00446879
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00446143
HPF1 histone PARylation factor 1 -0.0044481
COX5B cytochrome c oxidase subunit Vb -0.00444209
RALB v-ral simian leukemia viral oncogene homolog B -0.00443965
MXI1 MAX interactor 1, dimerization protein -0.00443919
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00443905
HIKESHI heat shock protein nuclear import factor hikeshi -0.0044293
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.00442836
JPT1 Jupiter microtubule associated homolog 1 -0.00442299
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00441925
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00441573
NDC1 NDC1 transmembrane nucleoporin -0.00441232
CA14 carbonic anhydrase XIV -0.00441087
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.00439972
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -0.00439877
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0043927
TMEM168 transmembrane protein 168 -0.00439178
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.00438505
CNTN1 contactin 1 -0.00438272