KSR1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description kinase suppressor of ras 1| (NCBI Entrez Gene Database, 8844)
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Genes

309 genes differentially expressed following the KSR1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 3.47153
CFAP47 cilia and flagella associated protein 47 3.47153
KRT86 keratin 86, type II 3.47153
OTOA otoancorin 3.47153
COMP cartilage oligomeric matrix protein 3.47153
HES7 hes family bHLH transcription factor 7 3.47153
RAD21L1 RAD21-like 1 (S. pombe) 3.47153
TUBA3D tubulin, alpha 3d 3.47153
SNX31 sorting nexin 31 3.47153
IZUMO3 IZUMO family member 3 3.47153
SPATA22 spermatogenesis associated 22 3.47153
C11ORF96 chromosome 11 open reading frame 96 3.47153
VTCN1 V-set domain containing T cell activation inhibitor 1 3.47153
SPINK1 serine peptidase inhibitor, Kazal type 1 3.47153
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 3.47153
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.47153
TDO2 tryptophan 2,3-dioxygenase 3.47153
CFHR5 complement factor H-related 5 3.47153
CHADL chondroadherin-like 3.47153
IZUMO4 IZUMO family member 4 3.47153
TMEM132D transmembrane protein 132D 3.47153
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 3.47153
ETV2 ets variant 2 3.47153
MINAR2 membrane integral NOTCH2 associated receptor 2 3.47153
ADRA2A adrenoceptor alpha 2A 3.47153
NOS2 nitric oxide synthase 2, inducible 3.45125
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3.36967
CELF6 CUGBP, Elav-like family member 6 3.36967
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 3.36967
FAM187B family with sequence similarity 187, member B 3.36967
FOLR1 folate receptor 1 (adult) 3.36967
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 3.36967
OR52H1 olfactory receptor, family 52, subfamily H, member 1 3.36967
PTP4A1 protein tyrosine phosphatase type IVA, member 1 3.36967
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 3.36967
C1ORF141 chromosome 1 open reading frame 141 3.36967
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.36967
KLHL33 kelch-like family member 33 3.36967
CCDC187 coiled-coil domain containing 187 3.36967
CELA1 chymotrypsin-like elastase family, member 1 3.36967
TTLL8 tubulin tyrosine ligase-like family member 8 3.36967
CX3CR1 chemokine (C-X3-C motif) receptor 1 3.36967
S100A1 S100 calcium binding protein A1 3.36967
NPIPA7 nuclear pore complex interacting protein family, member A7 3.36967
WNT8B wingless-type MMTV integration site family, member 8B 3.36967
TRPC5OS TRPC5 opposite strand 3.36967
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.36967
THRSP thyroid hormone responsive 3.36967
PGBDF plakoglobin binding and degradation factor 3.36967
ADTRP androgen-dependent TFPI-regulating protein 3.36967
SH2D6 SH2 domain containing 6 3.36967
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.36967
PTH2 parathyroid hormone 2 3.36967
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 3.36967
SPINT3 serine peptidase inhibitor, Kunitz type, 3 3.36967
PTGFR prostaglandin F receptor (FP) 3.36967
PRDM13 PR domain containing 13 3.36967
CFHR3 complement factor H-related 3 3.36967
GPR6 G protein-coupled receptor 6 3.36967
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.36967
SPATS1 spermatogenesis associated, serine-rich 1 3.36967
PCDHGA9 protocadherin gamma subfamily A, 9 3.36967
PROP1 PROP paired-like homeobox 1 3.36967
CLDN14 claudin 14 3.36967
FRG2C FSHD region gene 2 family, member C 3.36967
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 3.36967
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 3.36967
JAML junction adhesion molecule like 3.36967
DNAAF6 dynein axonemal assembly factor 6 3.36967
SAXO5 stabilizer of axonemal microtubules 5 3.36967
PPIAL4H peptidylprolyl isomerase A like 4H 3.36967
SPMIP3 sperm microtubule inner protein 3 3.36967
LOC124903233 uncharacterized LOC124903233 3.36967
SMIM45 small integral membrane protein 45 3.36967
SPAAR small regulatory polypeptide of amino acid response 3.36967
RHEX regulator of hemoglobinization and erythroid cell expansion 3.36967
CLTRN collectrin, amino acid transport regulator 3.36967
PAPOLB poly(A) polymerase beta (testis specific) 3.36967
TSPAN1 tetraspanin 1 3.36967
THPO thrombopoietin 3.36967
PTGDR2 prostaglandin D2 receptor 2 3.36967
PTPRC protein tyrosine phosphatase, receptor type, C 3.36967
SLC35D3 solute carrier family 35, member D3 3.36967
RAB44 RAB44, member RAS oncogene family 3.36967
CD300LG CD300 molecule-like family member g 3.36967
FAM3D family with sequence similarity 3, member D 3.36967
TAS2R7 taste receptor, type 2, member 7 3.36967
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 3.36967
HPR haptoglobin-related protein 3.36967
TBX10 T-box 10 3.36967
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 3.36967
LTB lymphotoxin beta (TNF superfamily, member 3) 3.36967
TAS1R1 taste receptor, type 1, member 1 3.36967
S100B S100 calcium binding protein B 3.36967
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.36967
CXCL14 chemokine (C-X-C motif) ligand 14 3.36967
IDO2 indoleamine 2,3-dioxygenase 2 3.36967
CIMIP2B ciliary microtubule inner protein 2B 3.36967
ACKR2 atypical chemokine receptor 2 3.36967
MRLN myoregulin 3.36967
CNTF ciliary neurotrophic factor 3.36967
ERICH3 glutamate-rich 3 3.36967
CT55 cancer/testis antigen 55 3.36967
LCNL1 lipocalin-like 1 3.36967
EFCAB3 EF-hand calcium binding domain 3 3.36967
ADGRA1 adhesion G protein-coupled receptor A1 3.36967
C9ORF64 chromosome 9 open reading frame 64 3.36967
CTAGE9 CTAGE family, member 9 3.36967
SHOX2 short stature homeobox 2 3.36967
MYF6 myogenic factor 6 (herculin) 3.36967
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 3.36967
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.36967
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 3.36967
STAB1 stabilin 1 3.36967
MRPL47 mitochondrial ribosomal protein L47 3.36967
SLC25A52 solute carrier family 25, member 52 3.36967
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 3.36967
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.36967
TH tyrosine hydroxylase 3.36967
CYSLTR1 cysteinyl leukotriene receptor 1 3.36967
RNASE11 ribonuclease, RNase A family, 11 (non-active) 3.36967
TRADD TNFRSF1A-associated via death domain 3.36967
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.36967
PLA1A phospholipase A1 member A 3.36967
CLEC9A C-type lectin domain family 9, member A 3.36967
FCRLA Fc receptor-like A 3.36967
PRH2 proline-rich protein HaeIII subfamily 2 3.36967
ESPNL espin-like 3.36967
HLA-DMB major histocompatibility complex, class II, DM beta 3.36967
VMO1 vitelline membrane outer layer 1 homolog (chicken) 3.36967
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 3.36967
ISL1 ISL LIM homeobox 1 3.36967
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.36967
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 3.36967
TCP11X2 t-complex 11 family, X-linked 2 3.36967
CD244 CD244 molecule, natural killer cell receptor 2B4 3.36967
CBX8 chromobox homolog 8 3.36967
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 3.36967
TRIM55 tripartite motif containing 55 3.36967
CAGE1 cancer antigen 1 3.36967
VWA3A von Willebrand factor A domain containing 3A 3.36967
VWA3B von Willebrand factor A domain containing 3B 3.36967
UPK1B uroplakin 1B 3.36967
FAM25C family with sequence similarity 25, member C 3.36967
MYOZ2 myozenin 2 3.36967
A1CF APOBEC1 complementation factor 3.36967
OR51I2 olfactory receptor, family 51, subfamily I, member 2 3.36967
CXCL2 chemokine (C-X-C motif) ligand 2 3.36967
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.36967
ZPLD1 zona pellucida-like domain containing 1 3.36967
ARMCX6 armadillo repeat containing, X-linked 6 3.36967
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 3.36967
PADI6 peptidyl arginine deiminase, type VI 3.36967
GCM2 glial cells missing homolog 2 (Drosophila) 3.36967
PPP1R3A protein phosphatase 1, regulatory subunit 3A 3.36967
CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 3.36967
ZNF804B zinc finger protein 804B 3.36967
RBP4 retinol binding protein 4, plasma 3.36967
ABRA actin binding Rho activating protein 3.36967
LDHC lactate dehydrogenase C 3.36967
ASCL3 achaete-scute family bHLH transcription factor 3 3.36967
ZNF648 zinc finger protein 648 3.36967
THEM6 thioesterase superfamily member 6 3.36967
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 3.36967
CLK3 CDC-like kinase 3 3.31155
CHP2 calcineurin-like EF-hand protein 2 3.21587
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 3.21587
FNDC4 fibronectin type III domain containing 4 3.20729
SRSF2 serine/arginine-rich splicing factor 2 3.14305
ZNF45 zinc finger protein 45 3.13969
USP16 ubiquitin specific peptidase 16 3.13666
ANGPT1 angiopoietin 1 2.92298
RNF103 ring finger protein 103 2.92095
NKX3-1 NK3 homeobox 1 2.92095
FBXO16 F-box protein 16 2.89335
BAIAP2L2 BAI1-associated protein 2-like 2 2.83954
JMY junction mediating and regulatory protein, p53 cofactor 2.73201
KIRREL3 kin of IRRE like 3 (Drosophila) 2.66938
TBPL1 TBP-like 1 2.62779
ZFP41 ZFP41 zinc finger protein 2.58541
ZNF830 zinc finger protein 830 2.58165
ARSL arylsulfatase L 2.5454
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.54506
PIH1D2 PIH1 domain containing 2 2.472
OCLN occludin 2.46841
OTULIN OTU deubiquitinase with linear linkage specificity 2.46484
CAMKV CaM kinase-like vesicle-associated 2.44715
POU3F1 POU class 3 homeobox 1 2.41048
KANTR KDM5C adjacent non-coding transcript 2.38755
CPTP ceramide-1-phosphate transfer protein 2.38755
CENPV centromere protein V 2.36374
MRC1 mannose receptor, C type 1 2.35327
NPHP4 nephronophthisis 4 2.32874
MYRF myelin regulatory factor 2.31973
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 2.29497
PHF13 PHD finger protein 13 2.28347
TOR1A torsin family 1, member A (torsin A) 2.27912
SELENOK selenoprotein K 2.26281
MEGF6 multiple EGF-like-domains 6 2.25432
MACO1 macoilin 1 2.22626
CENPA centromere protein A 2.2151
SIKE1 suppressor of IKBKE 1 2.20748
ZNF771 zinc finger protein 771 2.19679
MED15 mediator complex subunit 15 2.18329
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 2.17764
ZNF468 zinc finger protein 468 2.16763
UNC93A unc-93 homolog A (C. elegans) 2.14963
PCDHB12 protocadherin beta 12 2.14963
CD1D CD1d molecule 2.14963
ADAM33 ADAM metallopeptidase domain 33 2.14963
NEK10 NIMA-related kinase 10 2.12033
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 2.11407
ZNF808 zinc finger protein 808 2.11339
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 2.09677
PNISR PNN-interacting serine/arginine-rich protein 2.07789
JUND jun D proto-oncogene 2.03972
FDXR ferredoxin reductase 2.03467
GCSH glycine cleavage system protein H (aminomethyl carrier) 2.03416
PHOSPHO2 phosphatase, orphan 2 2.01598
ZNF723 zinc finger protein 723 2.01577
TTPA tocopherol (alpha) transfer protein 2.01577
SMAD2 SMAD family member 2 2.01261
EHD2 EH-domain containing 2 2.00317
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.00317
STIMATE STIM activating enhancer 2.00236

decreased expression

Symbol Name Standardized Value
PRSS3 protease, serine, 3 -3.47153
COL11A2 collagen, type XI, alpha 2 -3.47153
DUSP15 dual specificity phosphatase 15 -3.47153
RGPD5 RANBP2-like and GRIP domain containing 5 -3.47153
WDR72 WD repeat domain 72 -3.47153
DNAH12 dynein, axonemal, heavy chain 12 -3.36967
IL4I1 interleukin 4 induced 1 -3.36967
AMIGO1 adhesion molecule with Ig-like domain 1 -3.36967
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -3.36967
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -3.36967
NTSR1 neurotensin receptor 1 (high affinity) -3.36967
SHOX short stature homeobox -3.36967
C9ORF57 chromosome 9 open reading frame 57 -3.36967
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -3.36967
ZNF324B zinc finger protein 324B -3.36967
ADAM29 ADAM metallopeptidase domain 29 -3.36967
SFTA2 surfactant associated 2 -3.36967
SLC22A14 solute carrier family 22, member 14 -3.36967
EMX1 empty spiracles homeobox 1 -3.36967
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -3.36967
NPIPB7 nuclear pore complex interacting protein family, member B7 -3.36967
INSL3 insulin-like 3 (Leydig cell) -3.36967
CSF1R colony stimulating factor 1 receptor -3.36967
PP2D1 protein phosphatase 2C-like domain containing 1 -3.36967
ICOSLG inducible T-cell co-stimulator ligand -3.36967
ZNF804A zinc finger protein 804A -3.36967
KLK4 kallikrein-related peptidase 4 -3.36967
CPZ carboxypeptidase Z -3.36967
OR2A1 olfactory receptor, family 2, subfamily A, member 1 -3.36967
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -3.36967
SSC5D scavenger receptor cysteine rich family, 5 domains -3.36967
C2CD4A C2 calcium-dependent domain containing 4A -3.36967
CUL7 cullin 7 -3.21566
RUVBL2 RuvB-like AAA ATPase 2 -3.17442
REEP4 receptor accessory protein 4 -3.10387
L3MBTL3 l(3)mbt-like 3 (Drosophila) -2.98738
H2BC15 H2B clustered histone 15 -2.91259
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.86007
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 -2.86007
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.65567
RTF2 replication termination factor 2 -2.65567
THAP11 THAP domain containing 11 -2.6182
PTCD3 pentatricopeptide repeat domain 3 -2.6182
NPIPA2 nuclear pore complex interacting protein family, member A2 -2.58541
TULP2 tubby like protein 2 -2.58541
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 -2.54213
FHIP2B FHF complex subunit HOOK interacting protein 2B -2.48662
CKMT1A creatine kinase, mitochondrial 1A -2.47907
C1ORF53 chromosome 1 open reading frame 53 -2.47907
ZNF616 zinc finger protein 616 -2.47907
RASGEF1A RasGEF domain family, member 1A -2.47907
AQP5 aquaporin 5 -2.46484
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 -2.46484
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.43063
DNAL1 dynein, axonemal, light chain 1 -2.41488
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.38755
CARNMT1 carnosine N-methyltransferase 1 -2.37542
IGSF1 immunoglobulin superfamily, member 1 -2.36573
ACSL6 acyl-CoA synthetase long-chain family member 6 -2.34035
LHX8 LIM homeobox 8 -2.321
SYNPO2L synaptopodin 2-like -2.31189
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.29497
RFXANK regulatory factor X-associated ankyrin-containing protein -2.29497
NCAPH2 non-SMC condensin II complex, subunit H2 -2.27912
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -2.27888
ACOT7 acyl-CoA thioesterase 7 -2.27883
HES1 hes family bHLH transcription factor 1 -2.26919
IQSEC1 IQ motif and Sec7 domain 1 -2.2501
PRRX2 paired related homeobox 2 -2.2249
SPATA6L spermatogenesis associated 6-like -2.22052
COPG1 coatomer protein complex, subunit gamma 1 -2.17311
MTNR1A melatonin receptor 1A -2.16191
ZFP28 ZFP28 zinc finger protein -2.15441
ANGEL2 angel homolog 2 (Drosophila) -2.14963
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.14963
FGFR1 fibroblast growth factor receptor 1 -2.10148
KIDINS220 kinase D-interacting substrate, 220kDa -2.08359
MAP2K2 mitogen-activated protein kinase kinase 2 -2.06945
PLEKHA7 pleckstrin homology domain containing, family A member 7 -2.06519
RNF157 ring finger protein 157 -2.06477
E2F7 E2F transcription factor 7 -2.04773
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.04759
MSL1 male-specific lethal 1 homolog (Drosophila) -2.01598
USP21 ubiquitin specific peptidase 21 -2.01598