KYSE-140 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Esophageal Squamous Cell Carcinoma Tumour (Cell Model Passports, SIDM01032)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM01032
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Genes

196 proteins associated with the cell line KYSE-140 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ARGLU1 arginine and glutamate rich 1
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
BCAM basal cell adhesion molecule (Lutheran blood group)
BCAS2 breast carcinoma amplified sequence 2
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BRD4 bromodomain containing 4
C1ORF50 chromosome 1 open reading frame 50
CCAR1 cell division cycle and apoptosis regulator 1
CCDC126 coiled-coil domain containing 126
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDC5L cell division cycle 5-like
CHD3 chromodomain helicase DNA binding protein 3
CHERP calcium homeostasis endoplasmic reticulum protein
CMC2 C-x(9)-C motif containing 2
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
CPT1A carnitine palmitoyltransferase 1A (liver)
CUX1 cut-like homeobox 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DHCR7 7-dehydrocholesterol reductase
DHRS4 dehydrogenase/reductase (SDR family) member 4
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19
DPYD dihydropyrimidine dehydrogenase
DSP desmoplakin
EBAG9 estrogen receptor binding site associated, antigen, 9
EPDR1 ependymin related 1
FAM120C family with sequence similarity 120C
FBN2 fibrillin 2
FECH ferrochelatase
FIP1L1 factor interacting with PAPOLA and CPSF1
FKBP9 FK506 binding protein 9, 63 kDa
FXR1 fragile X mental retardation, autosomal homolog 1
HMG20A high mobility group 20A
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone
HSPA9 heat shock 70kDa protein 9 (mortalin)
IGFBPL1 insulin-like growth factor binding protein-like 1
INO80B INO80 complex subunit B
INTS12 integrator complex subunit 12
KIAA1217 KIAA1217
KLC3 kinesin light chain 3
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LOC101929615 uncharacterized LOC101929615
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP7D2 MAP7 domain containing 2
MAPT microtubule-associated protein tau
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MECR mitochondrial trans-2-enoyl-CoA reductase
MSRB2 methionine sulfoxide reductase B2
MT-ATP8 ATP synthase F0 subunit 8
NUBPL nucleotide binding protein-like
NUP214 nucleoporin 214kDa
PABPN1 poly(A) binding protein, nuclear 1
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCCA propionyl CoA carboxylase, alpha polypeptide
PCCB propionyl CoA carboxylase, beta polypeptide
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCNT pericentrin
PEG3 paternally expressed 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PHF5A PHD finger protein 5A
PLRG1 pleiotropic regulator 1
PNN pinin, desmosome associated protein
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCSH protein kinase C substrate 80K-H
RBM17 RNA binding motif protein 17
RBM27 RNA binding motif protein 27
RREB1 ras responsive element binding protein 1
SACK1B scaffolding CK1 anchoring protein B
SAP18 Sin3A-associated protein, 18kDa
SCAF11 SR-related CTD-associated factor 11
SDK1 sidekick cell adhesion molecule 1
SFPQ splicing factor proline/glutamine-rich
SIPA1L3 signal-induced proliferation-associated 1 like 3
STRN3 striatin, calmodulin binding protein 3
SYNE2 spectrin repeat containing, nuclear envelope 2
TBC1D15 TBC1 domain family, member 15
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast)
TPR translocated promoter region, nuclear basket protein
TTC22 tetratricopeptide repeat domain 22
TTC27 tetratricopeptide repeat domain 27
U2SURP U2 snRNP-associated SURP domain containing
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WIZ widely interspaced zinc finger motifs
YLPM1 YLP motif containing 1
ZC3H13 zinc finger CCCH-type containing 13
ZC3H14 zinc finger CCCH-type containing 14
ZNF740 zinc finger protein 740

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ANXA6 annexin A6
APOB apolipoprotein B
APOL2 apolipoprotein L, 2
ARMC1 armadillo repeat containing 1
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
CORO7 coronin 7
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
DCTD dCMP deaminase
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DESI1 desumoylating isopeptidase 1
DRG1 developmentally regulated GTP binding protein 1
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
ERCC6L excision repair cross-complementation group 6-like
FLII flightless I homolog (Drosophila)
FNTA farnesyltransferase, CAAX box, alpha
GPHN gephyrin
GRIPAP1 GRIP1 associated protein 1
HAUS4 HAUS augmin-like complex, subunit 4
HDAC1 histone deacetylase 1
HK2 hexokinase 2
HS1BP3 HCLS1 binding protein 3
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
IL18 interleukin 18
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KIF16B kinesin family member 16B
KIF2C kinesin family member 2C
KPNA7 karyopherin alpha 7 (importin alpha 8)
LAMA2 laminin, alpha 2
LAT2 linker for activation of T cells family, member 2
LINC01205 long intergenic non-protein coding RNA 1205
MAP2K4 mitogen-activated protein kinase kinase 4
MCRIP2 MAPK regulated corepressor interacting protein 2
METTL1 methyltransferase like 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPZL1 myelin protein zero-like 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYO19 myosin XIX
NDRG3 NDRG family member 3
NOTCH2 notch 2
NTF3 neurotrophin 3
ORC3 origin recognition complex, subunit 3
PACS1 phosphofurin acidic cluster sorting protein 1
PDCD2 programmed cell death 2
PDE12 phosphodiesterase 12
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNPLA6 patatin-like phospholipase domain containing 6
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP6C protein phosphatase 6, catalytic subunit
PRMT3 protein arginine methyltransferase 3
PSAP prosaposin
PSMG4 proteasome (prosome, macropain) assembly chaperone 4
PTDSS2 phosphatidylserine synthase 2
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB35 RAB35, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RNF149 ring finger protein 149
RPE ribulose-5-phosphate-3-epimerase
RPL18A ribosomal protein L18a
RPP30 ribonuclease P/MRP 30kDa subunit
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SCARB1 scavenger receptor class B, member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SMYD3 SET and MYND domain containing 3
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK3 TAO kinase 3
TGFB2 transforming growth factor, beta 2
THUMPD1 THUMP domain containing 1
TPRKB TP53RK binding protein
TRAPPC8 trafficking protein particle complex 8
TRIP4 thyroid hormone receptor interactor 4
TRRAP transformation/transcription domain-associated protein
TSC22D1 TSC22 domain family, member 1
TTK TTK protein kinase
TXNDC9 thioredoxin domain containing 9
UBA3 ubiquitin-like modifier activating enzyme 3
VAC14 Vac14 homolog (S. cerevisiae)
VARS2 valyl-tRNA synthetase 2, mitochondrial
VRK2 vaccinia related kinase 2
WLS wntless Wnt ligand secretion mediator
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF703 zinc finger protein 703
ZW10 zw10 kinetochore protein