KYSE-50 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description cell line derived from -666 (Catalogue of Somatic Mutations In Cancer)
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Genes

304 genes with high or low copy number in KYSE-50 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
RCE1 Ras converting CAAX endopeptidase 1 2.39327
C11ORF80 chromosome 11 open reading frame 80 2.39327
C11ORF86 chromosome 11 open reading frame 86 2.39327
SYT12 synaptotagmin XII 2.39327
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.39327
PC pyruvate carboxylase 2.39327
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 2.36889
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 2.36889
SPAG1 sperm associated antigen 1 2.36889
FLJ42969 uncharacterized LOC441374 2.36889
ANKRD46 ankyrin repeat domain 46 2.35236
SNX31 sorting nexin 31 2.35236
FBXO43 F-box protein 43 2.35236
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.35236
BAALC brain and acute leukemia, cytoplasmic 2.35236
RGS22 regulator of G-protein signaling 22 2.35236
PABPC1 poly(A) binding protein, cytoplasmic 1 2.35236
MIR4471 microRNA 4471 2.35236
MIR3151 microRNA 3151 2.35236
FZD6 frizzled class receptor 6 2.35236
COX6C cytochrome c oxidase subunit VIc 2.35236
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 2.3178
CTHRC1 collagen triple helix repeat containing 1 2.3178
ZNF706 zinc finger protein 706 2.3178
KLF10 Kruppel-like factor 10 2.3178
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 2.3178
UBR5 ubiquitin protein ligase E3 component n-recognin 5 2.30944
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 2.30944
AZIN1 antizyme inhibitor 1 2.30944
MIR5680 microRNA 5680 2.30944
NCALD neurocalcin delta 2.30944
DCAF13 DDB1 and CUL4 associated factor 13 2.30944
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 2.30944
VPS13B vacuolar protein sorting 13 homolog B (yeast) 2.283
ODF1 outer dense fiber of sperm tails 1 2.283
GRHL2 grainyhead-like 2 (Drosophila) 2.26395
LRP12 low density lipoprotein receptor-related protein 12 2.25904
DCSTAMP dendrocyte expressed seven transmembrane protein 2.25904
DPYS dihydropyrimidinase 2.25904
RIMS2 regulating synaptic membrane exocytosis 2 2.24139
RSPO2 R-spondin 2 2.24139
ENY2 enhancer of yellow 2 homolog (Drosophila) 2.24139
SYBU syntabulin (syntaxin-interacting) 2.24139
EMC2 ER membrane protein complex subunit 2 2.2355
TRHR thyrotropin-releasing hormone receptor 2.2355
NUDCD1 NudC domain containing 1 2.2355
EIF3E eukaryotic translation initiation factor 3, subunit E 2.2355
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 2.23324
EBAG9 estrogen receptor binding site associated, antigen, 9 2.23324
TMEM74 transmembrane protein 74 2.23078
ANGPT1 angiopoietin 1 2.22917
ZFPM2 zinc finger protein, FOG family member 2 2.22917
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.22917
ABRA actin binding Rho activating protein 2.22793
OXR1 oxidation resistance 1 2.22783
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast) 2.22558
MIR3610 microRNA 3610 2.22558
RAD21-AS1 RAD21 antisense RNA 1 2.22558
RAD21 RAD21 homolog (S. pombe) 2.22558
EIF3H eukaryotic translation initiation factor 3, subunit H 2.22291
AARD alanine and arginine rich domain containing protein 2.22291
LINC00536 long intergenic non-protein coding RNA 536 2.21727
MED30 mediator complex subunit 30 2.21258
SLC30A8 solute carrier family 30 (zinc transporter), member 8 2.21258
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 2.21096
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.21096
COLEC10 collectin sub-family member 10 (C-type lectin) 2.21096
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 2.20309
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.20309
SAMD12-AS1 SAMD12 antisense RNA 1 2.20309
ZDHHC11 zinc finger, DHHC-type containing 11 2.20309
DSCC1 DNA replication and sister chromatid cohesion 1 2.20309
NOV nephroblastoma overexpressed 2.20309
EXT1 exostosin glycosyltransferase 1 2.20053
SAMD12 sterile alpha motif domain containing 12 2.18778
DERL1 derlin 1 2.18778
SACK1A scaffolding CK1 anchoring protein A 2.18778
ZHX2 zinc fingers and homeoboxes 2 2.18778
FAM83A-AS1 FAM83A antisense RNA 1 2.18778
C8ORF76 chromosome 8 open reading frame 76 2.18124
DEPTOR DEP domain containing MTOR-interacting protein 2.18124
MIR4663 microRNA 4663 2.18124
KLHL38 kelch-like family member 38 2.17694
RNF139 ring finger protein 139 2.17694
HAS2 hyaluronan synthase 2 2.16947
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 2.16947
ATAD2 ATPase family, AAA domain containing 2 2.16947
WDYHV1 WDYHV motif containing 1 2.16947
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) 2.16947
MTBP MDM2 binding protein 2.16947
HAS2-AS1 HAS2 antisense RNA 1 2.16947
FBXO32 F-box protein 32 2.16947
ZHX1 zinc fingers and homeoboxes 1 2.16947
TMEM65 transmembrane protein 65 2.16816
MTSS1 metastasis suppressor 1 2.16816
ANXA13 annexin A13 2.16816
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 2.16816
TATDN1 TatD DNase domain containing 1 2.16816
COL14A1 collagen, type XIV, alpha 1 2.16625
MRPL13 mitochondrial ribosomal protein L13 2.16625
FAM91A1 family with sequence similarity 91, member A1 2.16625
FER1L6-AS1 FER1L6 antisense RNA 1 2.16625
SNORA31 small nucleolar RNA, H/ACA box 31 2.16564
ZNF572 zinc finger protein 572 2.16564
FER1L6 fer-1-like family member 6 2.16459
SQLE squalene epoxidase 2.16459
KIAA0196 KIAA0196 2.16459
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 2.16307
TRIB1 tribbles pseudokinase 1 2.16176
LINC00861 long intergenic non-protein coding RNA 861 2.15967
FAM84B family with sequence similarity 84, member B 2.15847
SNORD78 small nucleolar RNA, C/D box 78 2.12439
PCAT1 prostate cancer associated transcript 1 (non-protein coding) 2.08634
KIAA1551 KIAA1551 2.06989
RNU6-78P RNA, U6 small nuclear 78, pseudogene 2.06989
H3F3C H3 histone, family 3C 2.06989
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) 2.06626
DENND5B-AS1 DENND5B antisense RNA 1 2.06626
METTL20 methyltransferase like 20 2.06626
SNORD77 small nucleolar RNA, C/D box 77 2.06505
BICD1 bicaudal D homolog 1 (Drosophila) 2.06473
TSPAN11 tetraspanin 11 2.06473
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 2.06473
DDX11-AS1 DDX11 antisense RNA 1 2.06473
DENND5B DENN/MADD domain containing 5B 2.06473
OVOS2 ovostatin 2 2.06316
FAM60A family with sequence similarity 60, member A 2.06316
TMTC1 transmembrane and tetratricopeptide repeat containing 1 2.06316
FLJ13224 uncharacterized LOC79857 2.06316
LINC00941 long intergenic non-protein coding RNA 941 2.06316
SNORA75 small nucleolar RNA, H/ACA box 75 2.06233
OVCH1 ovochymase 1 2.0622
CAPRIN2 caprin family member 2 2.0622
OVCH1-AS1 OVCH1 antisense RNA 1 2.0622
IPO8 importin 8 2.0622
FAR2 fatty acyl CoA reductase 2 2.0622
ERGIC2 ERGIC and golgi 2 2.0622
CCAT1 colon cancer associated transcript 1 (non-protein coding) 2.0614
CCDC91 coiled-coil domain containing 91 2.06061
MANSC4 MANSC domain containing 4 2.06061
MRPS35 mitochondrial ribosomal protein S35 2.06061
KLHL42 kelch-like family member 42 2.06061
REP15 RAB15 effector protein 2.06061
ETNK1 ethanolamine kinase 1 2.05973
PTHLH parathyroid hormone-like hormone 2.05965
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 2.05965
C2CD5 C2 calcium-dependent domain containing 5 2.05965
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.05942
TM7SF3 transmembrane 7 superfamily member 3 2.05864
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 2.05864
FGFR1OP2 FGFR1 oncogene partner 2 2.05864
MED21 mediator complex subunit 21 2.05864
C12ORF71 chromosome 12 open reading frame 71 2.05864
BHLHE41 basic helix-loop-helix family, member e41 2.05778
ASUN asunder spermatogenesis regulator 2.05778
MIR2053 microRNA 2053 2.05778
STK38L serine/threonine kinase 38 like 2.05778
MIR920 microRNA 920 2.05673
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 2.05661
RASSF8-AS1 RASSF8 atnisense RNA 1 2.05661
MIR4302 microRNA 4302 2.05635
SSPN sarcospan 2.05635
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.0557
CSMD3 CUB and Sushi multiple domains 3 2.05477
LINC00477 long intergenic non-protein coding RNA 477 2.05441
TRPS1 trichorhinophalangeal syndrome I 2.05422
SOX5 SRY (sex determining region Y)-box 5 2.05408
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.05311
C12ORF77 chromosome 12 open reading frame 77 2.05311
LRMP lymphoid-restricted membrane protein 2.05242
LYRM5 LYR motif containing 5 2.0521
CASC1 cancer susceptibility candidate 1 2.0521
KRAS Kirsten rat sarcoma viral oncogene homolog 2.05093
SNORD112 small nucleolar RNA, C/D box 112 2.04693

low copy number

Symbol Name Standardized Value
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -3.83684
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -3.83684
MSR1 macrophage scavenger receptor 1 -3.7119
MIR383 microRNA 383 -3.61078
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 -3.486
ATG7 autophagy related 7 -3.32901
VGLL4 vestigial-like family member 4 -3.29865
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -3.18157
FAM171B family with sequence similarity 171, member B -3.15836
ZC3H15 zinc finger CCCH-type containing 15 -3.15836
OR2J2 olfactory receptor, family 2, subfamily J, member 2 -3.11641
KCNIP4-IT1 KCNIP4 intronic transcript 1 -3.05196
ITGAV integrin, alpha V -3.0433
EPHA3 EPH receptor A3 -3.00743
DLC1 DLC1 Rho GTPase activating protein -3.00044
C8ORF48 chromosome 8 open reading frame 48 -2.99615
KCNIP4 Kv channel interacting protein 4 -2.969
SYAP1 synapse associated protein 1 -2.9644
FANCB Fanconi anemia, complementation group B -2.9644
GK glycerol kinase -2.9644
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -2.9644
ADGRG2 adhesion G protein-coupled receptor G2 -2.9644
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.9644
RGN regucalcin -2.9644
HCCS holocytochrome c synthase -2.9644
PORCN porcupine homolog (Drosophila) -2.9644
MIR4768 microRNA 4768 -2.9644
TXLNG taxilin gamma -2.9644
CTPS2 CTP synthase 2 -2.9644
S100G S100 calcium binding protein G -2.9644
MOSPD2 motile sperm domain containing 2 -2.9644
EBP emopamil binding protein (sterol isomerase) -2.9644
GLRA2 glycine receptor, alpha 2 -2.9644
TBC1D25 TBC1 domain family, member 25 -2.9644
SCARNA9L small Cajal body-specific RNA 9-like -2.93929
EIF1AX eukaryotic translation initiation factor 1A, X-linked -2.93929
MAP7D2 MAP7 domain containing 2 -2.93929
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.93929
PQBP1 polyglutamine binding protein 1 -2.93416
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.93416
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 -2.93416
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.93416
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -2.93416
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.93416
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -2.93416
PHKA2 phosphorylase kinase, alpha 2 (liver) -2.93416
GATA1 GATA binding protein 1 (globin transcription factor 1) -2.93416
ARHGAP6 Rho GTPase activating protein 6 -2.93416
MAGEB5 melanoma antigen family B5 -2.93416
MAGEB6 melanoma antigen family B6 -2.93416
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -2.93416
ERAS ES cell expressed Ras -2.93416
MAGIX MAGI family member, X-linked -2.93416
RBM10 RNA binding motif protein 10 -2.93416
PRICKLE3 prickle homolog 3 (Drosophila) -2.93416
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 -2.93416
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.93416
CDK16 cyclin-dependent kinase 16 -2.93416
PPP1R3F protein phosphatase 1, regulatory subunit 3F -2.93416
GPKOW G patch domain and KOW motifs -2.93416
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2 -2.93416
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1 -2.93416
SCML2 sex comb on midleg-like 2 (Drosophila) -2.93416
WDR13 WD repeat domain 13 -2.93416
GAGE10 G antigen 10 -2.93416
USP11 ubiquitin specific peptidase 11 -2.93416
INE1 inactivation escape 1 (non-protein coding) -2.93416
HDAC6 histone deacetylase 6 -2.93416
UBA1 ubiquitin-like modifier activating enzyme 1 -2.93416
FOXP3 forkhead box P3 -2.93416
WDR45 WD repeat domain 45 -2.93416
MIR23C microRNA 23c -2.93416
PHKA2-AS1 PHKA2 antisense RNA 1 -2.93416
AMELX amelogenin, X-linked -2.93416
LOC729609 uncharacterized LOC729609 -2.93416
CCDC22 coiled-coil domain containing 22 -2.93416
CXORF21 chromosome X open reading frame 21 -2.93416
SYP synaptophysin -2.93416
PRAF2 PRA1 domain family, member 2 -2.93416
ARX aristaless related homeobox -2.91268
CXORF23 chromosome X open reading frame 23 -2.91268
TFE3 transcription factor binding to IGHM enhancer 3 -2.91268
GRIPAP1 GRIP1 associated protein 1 -2.91268
CCDC120 coiled-coil domain containing 120 -2.91268
GLOD5 glyoxalase domain containing 5 -2.91268
WAS Wiskott-Aldrich syndrome -2.91268
SH3KBP1 SH3-domain kinase binding protein 1 -2.91268
OTUD5 OTU deubiquitinase 5 -2.91268
LINC01545 long intergenic non-protein coding RNA 1545 -2.91268
RS1 retinoschisin 1 -2.91268
VENTXP1 VENT homeobox pseudogene 1 -2.91268
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 -2.91268
SMPX small muscle protein, X-linked -2.91268
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.91268
MAGEB18 melanoma antigen family B18 -2.91268
MAGEB10 melanoma antigen family B10 -2.91268
MAGEB16 melanoma antigen family B16 -2.91268
CFAP47 cilia and flagella associated protein 47 -2.91268
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -2.91268
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) -2.89201
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.89201
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -2.88947
NLGN4X neuroligin 4, X-linked -2.88947
XK X-linked Kx blood group -2.88947
CDKL5 cyclin-dependent kinase-like 5 -2.88947
TMEM47 transmembrane protein 47 -2.88947
KLHL34 kelch-like family member 34 -2.88947
RP2 retinitis pigmentosa 2 (X-linked recessive) -2.88947
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.87802
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -2.87269
VCX2 variable charge, X-linked 2 -2.87269
FTH1P18 ferritin, heavy polypeptide 1 pseudogene 18 -2.87269
MIR651 microRNA 651 -2.86624
VCX variable charge, X-linked -2.85607
PNPLA4 patatin-like phospholipase domain containing 4 -2.85607
FAM47C family with sequence similarity 47, member C -2.85574
MID1 midline 1 -2.84999
KDM6A lysine (K)-specific demethylase 6A -2.84592
MIR4767 microRNA 4767 -2.82043
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 -2.80688
DEFB104B defensin, beta 104B -2.79198
DEFB4B defensin, beta 4B -2.79198
SPAG11B sperm associated antigen 11B -2.79198
DEFB106A defensin, beta 106A -2.79198
DEFB103A defensin, beta 103A -2.78913
DMD dystrophin -2.78077
STS steroid sulfatase (microsomal), isozyme S -2.7778
IFNA8 interferon, alpha 8 -2.73024
IFNA1 interferon, alpha 1 -2.72828
IFNE interferon, epsilon -2.72466