KYSE-510 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma, squamous cell (Cell Line Ontology, CLO_0007135)
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Genes

307 genes with high or low expression in KYSE-510 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 3.29962
ZNF271P zinc finger protein 271, pseudogene 3.14779
DHCR7 7-dehydrocholesterol reductase 2.76543
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 2.69523
NADSYN1 NAD synthetase 1 2.61726
ENOSF1 enolase superfamily member 1 2.5942
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2.50852
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.40976
FGF21 fibroblast growth factor 21 2.37139
RUVBL2 RuvB-like AAA ATPase 2 2.37088
SNW1 SNW domain containing 1 2.27249
MOCOS molybdenum cofactor sulfurase 2.20233
MUC4 mucin 4, cell surface associated 2.13283
ZNF146 zinc finger protein 146 2.12626
HEATR1 HEAT repeat containing 1 2.09065
CPT1A carnitine palmitoyltransferase 1A (liver) 2.08203
MFN2 mitofusin 2 2.06575
EGLN2 egl-9 family hypoxia-inducible factor 2 2.06413
YES1 YES proto-oncogene 1, Src family tyrosine kinase 2.06225
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 2.02162
THOC1 THO complex 1 1.97376
METTL4 methyltransferase like 4 1.96151
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene 1.96018
ZNF410 zinc finger protein 410 1.95901
DENR density-regulated protein 1.87053
POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.85073
CTTN cortactin 1.84605
EXT1 exostosin glycosyltransferase 1 1.84589
NAT10 N-acetyltransferase 10 (GCN5-related) 1.83541
PVT1 Pvt1 oncogene (non-protein coding) 1.8226
TRIM44 tripartite motif containing 44 1.81887
EIF3H eukaryotic translation initiation factor 3, subunit H 1.81846
ZNF473 zinc finger protein 473 1.80684
CHMP4A charged multivesicular body protein 4A 1.80447
PNKP polynucleotide kinase 3'-phosphatase 1.78757
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 1.76522
PTPRK protein tyrosine phosphatase, receptor type, K 1.7609
TMEM40 transmembrane protein 40 1.75325
ECI1 enoyl-CoA delta isomerase 1 1.75219
RDH16 retinol dehydrogenase 16 (all-trans) 1.74967
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.74931
NDC80 NDC80 kinetochore complex component 1.73555
ESR1 estrogen receptor 1 1.72004
EGR4 early growth response 4 1.70943
WNT4 wingless-type MMTV integration site family, member 4 1.7005
FADS3 fatty acid desaturase 3 1.69879
JADE2 jade family PHD finger 2 1.67414
EIF3J eukaryotic translation initiation factor 3, subunit J 1.66709
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1.64699
APOL6 apolipoprotein L, 6 1.64159
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 1.63731
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 1.62382
ATF3 activating transcription factor 3 1.61959
MRPS10 mitochondrial ribosomal protein S10 1.61641
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.59551
ACACA acetyl-CoA carboxylase alpha 1.59319
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.58956
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 1.58276
CNOT3 CCR4-NOT transcription complex, subunit 3 1.58064
MLH3 mutL homolog 3 1.56604
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.55471
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 1.55036
KTN1 kinectin 1 (kinesin receptor) 1.54896
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding) 1.54816
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 1.54512
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.53633
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.5353
PIH1D1 PIH1 domain containing 1 1.52268
RAP2B RAP2B, member of RAS oncogene family 1.52215
API5 apoptosis inhibitor 5 1.51716
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.50522
ECH1 enoyl CoA hydratase 1, peroxisomal 1.49782
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 1.49412
FAF2 Fas associated factor family member 2 1.49202
CRCP CGRP receptor component 1.48355
PSEN1 presenilin 1 1.48265
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.48005
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.47343
BCL10 B-cell CLL/lymphoma 10 1.47143
SF3B5 splicing factor 3b, subunit 5, 10kDa 1.47102
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.46838
GCLC glutamate-cysteine ligase, catalytic subunit 1.46582
SCARB1 scavenger receptor class B, member 1 1.46356
DNPEP aspartyl aminopeptidase 1.45735
TBP TATA box binding protein 1.45155
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1.44848
DKC1 dyskeratosis congenita 1, dyskerin 1.44714
DCAF8 DDB1 and CUL4 associated factor 8 1.44454
HNRNPK heterogeneous nuclear ribonucleoprotein K 1.44363
SSRP1 structure specific recognition protein 1 1.44004
TXNL4B thioredoxin-like 4B 1.43922
FANCE Fanconi anemia, complementation group E 1.4379
PELP1 proline, glutamate and leucine rich protein 1 1.42737
FJX1 four jointed box 1 (Drosophila) 1.42545
CEL carboxyl ester lipase 1.42196
FNTA farnesyltransferase, CAAX box, alpha 1.42047
DCTD dCMP deaminase 1.42046

low expression

Symbol Name Standardized Value
ALAD aminolevulinate dehydratase -3.53725
ZNF444 zinc finger protein 444 -3.49913
PLA2G15 phospholipase A2, group XV -3.16568
CUL4B cullin 4B -3.16057
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.74369
ELSPBP1 epididymal sperm binding protein 1 -2.67993
ATF7 activating transcription factor 7 -2.66371
OXNAD1 oxidoreductase NAD-binding domain containing 1 -2.64107
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 -2.62317
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -2.52493
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -2.49771
ZNF140 zinc finger protein 140 -2.49512
CCDC40 coiled-coil domain containing 40 -2.4373
FRG1 FSHD region gene 1 -2.41804
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.41156
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic -2.3882
NAG18 NAG18 mRNA -2.3806
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -2.3756
TMEM19 transmembrane protein 19 -2.34194
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.33779
ZNF507 zinc finger protein 507 -2.33543
GPHN gephyrin -2.31996
CD93 CD93 molecule -2.3112
RS1 retinoschisin 1 -2.29907
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -2.2917
DCT dopachrome tautomerase -2.28794
ZNF93 zinc finger protein 93 -2.28045
TMEM57 transmembrane protein 57 -2.2713
GSTM4 glutathione S-transferase mu 4 -2.26815
LIG4 ligase IV, DNA, ATP-dependent -2.26289
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.26031
SEC23A Sec23 homolog A (S. cerevisiae) -2.25477
FMOD fibromodulin -2.24214
TMEM50B transmembrane protein 50B -2.23971
CUTA cutA divalent cation tolerance homolog (E. coli) -2.21708
SEC14L1 SEC14-like 1 (S. cerevisiae) -2.21313
SMYD3 SET and MYND domain containing 3 -2.18529
APOLD1 apolipoprotein L domain containing 1 -2.18113
CYTH4 cytohesin 4 -2.16964
ANKRD46 ankyrin repeat domain 46 -2.16403
MAEA macrophage erythroblast attacher -2.15146
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.12821
UBE4A ubiquitination factor E4A -2.1281
SERGEF secretion regulating guanine nucleotide exchange factor -2.1263
CPB1 carboxypeptidase B1 (tissue) -2.12127
MDFIC MyoD family inhibitor domain containing -2.11912
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 -2.11119
MRPS6 mitochondrial ribosomal protein S6 -2.10141
STAB2 stabilin 2 -2.10021
TMCC2 transmembrane and coiled-coil domain family 2 -2.10015
ZMAT3 zinc finger, matrin-type 3 -2.09533
PADI1 peptidyl arginine deiminase, type I -2.09171
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.06032
NLGN1 neuroligin 1 -2.05908
GPX3 glutathione peroxidase 3 -2.04901
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.04384
HIST1H2BD histone cluster 1, H2bd -2.02957
CGA glycoprotein hormones, alpha polypeptide -2.0232
SYNJ1 synaptojanin 1 -2.02089
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -2.0181
APC adenomatous polyposis coli -2.01285
ZNF415 zinc finger protein 415 -2.00859
PSG6 pregnancy specific beta-1-glycoprotein 6 -2.00827
OR2B2 olfactory receptor, family 2, subfamily B, member 2 -1.99696
B3GNT1 -1.97183
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -1.97175
RHOH ras homolog family member H -1.96988
FAM8A1 family with sequence similarity 8, member A1 -1.96902
ZSCAN5A zinc finger and SCAN domain containing 5A -1.95471
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) -1.93191
RBL2 retinoblastoma-like 2 -1.92813
TMX4 thioredoxin-related transmembrane protein 4 -1.92145
AGBL2 ATP/GTP binding protein-like 2 -1.90875
ROR1 receptor tyrosine kinase-like orphan receptor 1 -1.90292
ULK4 unc-51 like kinase 4 -1.90083
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) -1.89582
GALK1 galactokinase 1 -1.89296
SAMHD1 SAM domain and HD domain 1 -1.88808
ZNF286A zinc finger protein 286A -1.88614
PTH1R parathyroid hormone 1 receptor -1.88457
MPPE1 metallophosphoesterase 1 -1.88225
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -1.87366
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -1.8692
MXD4 MAX dimerization protein 4 -1.86183
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -1.86089
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -1.86088
ARCN1 archain 1 -1.85551
RHD Rh blood group, D antigen -1.84795
NTAN1 N-terminal asparagine amidase -1.83037
ARL15 ADP-ribosylation factor-like 15 -1.82834
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -1.82516
CD72 CD72 molecule -1.82054
ZMYM3 zinc finger, MYM-type 3 -1.81568
SNRPN small nuclear ribonucleoprotein polypeptide N -1.80508
POMT1 protein-O-mannosyltransferase 1 -1.80163
TSNAXIP1 translin-associated factor X interacting protein 1 -1.79558
DRD2 dopamine receptor D2 -1.79339
CIAO1 cytosolic iron-sulfur assembly component 1 -1.77223
OR2J2 olfactory receptor, family 2, subfamily J, member 2 -1.76944
CADPS2 Ca++-dependent secretion activator 2 -1.76779
ACOX1 acyl-CoA oxidase 1, palmitoyl -1.76159
FMO4 flavin containing monooxygenase 4 -1.761
NOTCH4 notch 4 -1.7582
KPNA5 karyopherin alpha 5 (importin alpha 6) -1.75393
LOC642236 FSHD region gene 1 pseudogene -1.75165
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 -1.74766
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -1.74565
PXMP4 peroxisomal membrane protein 4, 24kDa -1.73819
RECQL4 RecQ protein-like 4 -1.72916
MGMT O-6-methylguanine-DNA methyltransferase -1.72804
ABHD17A abhydrolase domain containing 17A -1.71936
FLNC filamin C, gamma -1.71583
ZNF75D zinc finger protein 75D -1.711
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -1.70921
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -1.70825
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -1.70651
C2CD2L C2CD2-like -1.70591
MTMR8 myotubularin related protein 8 -1.70061
ANKRD12 ankyrin repeat domain 12 -1.70054
TSC22D4 TSC22 domain family, member 4 -1.70042
TMEM9B TMEM9 domain family, member B -1.69673
LPL lipoprotein lipase -1.69582
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -1.69395
SLAMF7 SLAM family member 7 -1.69314
EMX1 empty spiracles homeobox 1 -1.68682
PIAS2 protein inhibitor of activated STAT, 2 -1.68316
ADAMTSL4 ADAMTS-like 4 -1.68004
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -1.67655
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -1.66743
SIDT2 SID1 transmembrane family, member 2 -1.66675
TBC1D2B TBC1 domain family, member 2B -1.6609
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -1.65701
CHST10 carbohydrate sulfotransferase 10 -1.65443
SYN2 synapsin II -1.65037
CEP112 centrosomal protein 112kDa -1.64472
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -1.64422
CFAP74 cilia and flagella associated protein 74 -1.63752
SCD5 stearoyl-CoA desaturase 5 -1.63647
VAMP4 vesicle-associated membrane protein 4 -1.63407
MEIS3P1 Meis homeobox 3 pseudogene 1 -1.63004
RFX5 regulatory factor X, 5 (influences HLA class II expression) -1.62968
BPGM 2,3-bisphosphoglycerate mutase -1.62959
ACAD8 acyl-CoA dehydrogenase family, member 8 -1.61416
ZNF214 zinc finger protein 214 -1.6095
RRAGB Ras-related GTP binding B -1.60573
EFNB3 ephrin-B3 -1.60108
BHLHE41 basic helix-loop-helix family, member e41 -1.59834
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -1.59734
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -1.59084
RAB8B RAB8B, member RAS oncogene family -1.58876
MOSPD3 motile sperm domain containing 3 -1.58544
JRK Jrk homolog (mouse) -1.58501
HIPK1 homeodomain interacting protein kinase 1 -1.58446
LIN7B lin-7 homolog B (C. elegans) -1.5823
PCLO piccolo presynaptic cytomatrix protein -1.58227
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -1.5809
AVPR1A arginine vasopressin receptor 1A -1.58003
LIN28A lin-28 homolog A (C. elegans) -1.57518
NRP1 neuropilin 1 -1.57469
NARF nuclear prelamin A recognition factor -1.57016
TRAF2 TNF receptor-associated factor 2 -1.56938
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -1.566
TUBA4B tubulin, alpha 4b -1.56558
FKBP5 FK506 binding protein 5 -1.5609
ZNF91 zinc finger protein 91 -1.56039
ABHD14A abhydrolase domain containing 14A -1.55058
ZNF134 zinc finger protein 134 -1.54986
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -1.5493
PAAF1 proteasomal ATPase-associated factor 1 -1.54838
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -1.54574
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -1.54286
IL2RG interleukin 2 receptor, gamma -1.53814
MYT1 myelin transcription factor 1 -1.53579
LRRC23 leucine rich repeat containing 23 -1.53479
PHTF1 putative homeodomain transcription factor 1 -1.53417
ATP10A ATPase, class V, type 10A -1.52638
CBLN1 cerebellin 1 precursor -1.52609
EPOR erythropoietin receptor -1.52451
SIGLEC6 sialic acid binding Ig-like lectin 6 -1.5224
CASR calcium-sensing receptor -1.51985
TBCCD1 TBCC domain containing 1 -1.51819
TAS2R16 taste receptor, type 2, member 16 -1.51774
ETV1 ets variant 1 -1.51434
MRPL34 mitochondrial ribosomal protein L34 -1.51342
MYBPC3 myosin binding protein C, cardiac -1.51236
ZNF443 zinc finger protein 443 -1.51232
ABT1 activator of basal transcription 1 -1.51083
CRTC1 CREB regulated transcription coactivator 1 -1.50511
MINPP1 multiple inositol-polyphosphate phosphatase 1 -1.49685
COMMD3 COMM domain containing 3 -1.49447
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -1.49152
FSD1 fibronectin type III and SPRY domain containing 1 -1.48755
ZNF117 zinc finger protein 117 -1.48736
VAX2 ventral anterior homeobox 2 -1.47942
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.47115
CAPRIN2 caprin family member 2 -1.46899
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -1.46517
PRDX2 peroxiredoxin 2 -1.46171
PTPRB protein tyrosine phosphatase, receptor type, B -1.46068
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -1.45714
KIAA1654 KIAA1654 protein -1.45274
CTPS2 CTP synthase 2 -1.44625
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -1.44172
MYBPC1 myosin binding protein C, slow type -1.44154
UGT8 UDP glycosyltransferase 8 -1.43714
JAM3 junctional adhesion molecule 3 -1.42702
TRIP4 thyroid hormone receptor interactor 4 -1.42624
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 -1.42376
BTN2A1 butyrophilin, subfamily 2, member A1 -1.4232
GPR4 G protein-coupled receptor 4 -1.41683