KYSE-70 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: carcinoma, squamous cell (Cell Line Ontology, CLO_0007137)
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Genes

213 genes with high or low copy number in KYSE-70 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
LRRC42 leucine rich repeat containing 42 4.51153
MRPL37 mitochondrial ribosomal protein L37 4.51153
CYB5RL cytochrome b5 reductase-like 4.51153
LDLRAD1 low density lipoprotein receptor class A domain containing 1 4.51153
CDCP2 CUB domain containing protein 2 4.51153
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 4.51153
TMEM59 transmembrane protein 59 4.51153
MIR4781 microRNA 4781 4.51153
SSBP3 single stranded DNA binding protein 3 3.12177
MRVI1 murine retrovirus integration site 1 homolog 3.12177
YME1L1 YME1-like 1 ATPase 2.76305
MYO3A myosin IIIA 2.76305
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.76305
RAB18 RAB18, member RAS oncogene family 2.76305
PTCHD3 patched domain containing 3 2.76305
ACBD5 acyl-CoA binding domain containing 5 2.76305
LRRC37A6P leucine rich repeat containing 37, member A6, pseudogene 2.76305
MASTL microtubule associated serine/threonine kinase-like 2.76305
GSTA2 glutathione S-transferase alpha 2 2.64759
LYZL2 lysozyme-like 2 2.64759
ANKRD26 ankyrin repeat domain 26 2.64759
GSTA3 glutathione S-transferase alpha 3 2.64759
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.64759
MTPAP mitochondrial poly(A) polymerase 2.64759
LINC00264 long intergenic non-protein coding RNA 264 2.64759
ICK intestinal cell (MAK-like) kinase 2.64759
GSTA1 glutathione S-transferase alpha 1 2.64759
GSTA5 glutathione S-transferase alpha 5 2.64759
GSTA7P glutathione S-transferase alpha 7, pseudogene 2.64759
ABI1 abl-interactor 1 2.64759
GCM1 glial cells missing homolog 1 (Drosophila) 2.64759
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 2.64759
FBXO9 F-box protein 9 2.64759
GSTA4 glutathione S-transferase alpha 4 2.64759
LINC00202-1 long intergenic non-protein coding RNA 202-1 2.64759
LINC00202-2 long intergenic non-protein coding RNA 202-2 2.64759
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.64759
KIAA1462 KIAA1462 2.59653
PAQR8 progestin and adipoQ receptor family member VIII 2.59653
MIR206 microRNA 206 2.59653
TRAM2 translocation associated membrane protein 2 2.59653
TRAM2-AS1 TRAM2 antisense RNA 1 (head to head) 2.59653
GPR158 G protein-coupled receptor 158 2.59653
GPR158-AS1 GPR158 antisense RNA 1 2.59653
LOC730101 uncharacterized LOC730101 2.59653
TMEM14A transmembrane protein 14A 2.59653
MIR133B microRNA 133b 2.59653
ENKUR enkurin, TRPC channel interacting protein 2.59653
MIR5586 microRNA 5586 2.49065
IL17A interleukin 17A 2.49065
ARMC4 armadillo repeat containing 4 2.49065
BAMBI BMP and activin membrane-bound inhibitor 2.49065
LINC00837 long intergenic non-protein coding RNA 837 2.49065
WAC-AS1 WAC antisense RNA 1 (head to head) 2.49065
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 2.49065
MCM3 minichromosome maintenance complex component 3 2.49065
LYZL1 lysozyme-like 1 2.49065
MKX mohawk homeobox 2.49065
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 2.49065
WAC WW domain containing adaptor with coiled-coil 2.49065
IL17F interleukin 17F 2.49065
PTCHD3P1 patched domain containing 3 pseudogene 1 2.49065
EFHC1 EF-hand domain (C-terminal) containing 1 2.49065
LINC00470 long intergenic non-protein coding RNA 470 2.44392
DGKG diacylglycerol kinase, gamma 90kDa 2.44392
ADIPOQ-AS1 ADIPOQ antisense RNA 1 2.44392
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 2.44392
ADIPOQ adiponectin, C1Q and collagen domain containing 2.44392
DLGAP1-AS4 DLGAP1 antisense RNA 4 2.44392
DLGAP1-AS3 DLGAP1 antisense RNA 3 2.44392
RPL39L ribosomal protein L39-like 2.44392
NDC80 NDC80 kinetochore complex component 2.41451
LOC344887 NmrA-like family domain containing 1 pseudogene 2.41451
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 2.41451
SNORD2 small nucleolar RNA, C/D box 2 2.41451
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 2.41451
ENOSF1 enolase superfamily member 1 2.41451
CRYGS crystallin, gamma S 2.41451
ETV5 ets variant 5 2.41451
METTL4 methyltransferase like 4 2.41451
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.41451
TRA2B transformer 2 beta homolog (Drosophila) 2.41451
EIF4A2 eukaryotic translation initiation factor 4A2 2.41451
FETUB fetuin B 2.41451
RTP1 receptor (chemosensory) transporter protein 1 2.41451
RTP4 receptor (chemosensory) transporter protein 4 2.41451
YES1 YES proto-oncogene 1, Src family tyrosine kinase 2.41451
HRG histidine-rich glycoprotein 2.41451
TBCCD1 TBCC domain containing 1 2.41451
CBX3P2 chromobox homolog 3 pseudogene 2 2.41451
CLUL1 clusterin-like 1 (retinal) 2.41451
LOC253573 uncharacterized LOC253573 2.41451
AHSG alpha-2-HS-glycoprotein 2.41451
TYMS thymidylate synthetase 2.41451
SNORA4 small nucleolar RNA, H/ACA box 4 2.41451
RFC4 replication factor C (activator 1) 4, 37kDa 2.41451
SNORA81 small nucleolar RNA, H/ACA box 81 2.41451
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 2.39327
TMEM41A transmembrane protein 41A 2.39327
IGF2BP2-AS1 IGF2BP2 antisense RNA 1 2.39327
MAP6D1 MAP6 domain containing 1 2.39327
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.39327
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 2.39327
LIPH lipase, member H 2.39327
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.39327
FAM131A family with sequence similarity 131, member A 2.39327
TGIF1 TGFB-induced factor homeobox 1 2.39327
MYL12B myosin, light chain 12B, regulatory 2.39327
DLGAP1-AS1 DLGAP1 antisense RNA 1 2.39327
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.39327
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.39327
CHRD chordin 2.39327
ABCC5-AS1 ABCC5 antisense RNA 1 2.39327
PARL presenilin associated, rhomboid-like 2.39327
CLCN2 chloride channel, voltage-sensitive 2 2.39327
THPO thrombopoietin 2.39327
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 2.39327
MIR1224 microRNA 1224 2.36889
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.36889
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.36889
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.36889
YEATS2 YEATS domain containing 2 2.36889
MAP3K13 mitogen-activated protein kinase kinase kinase 13 2.36889
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.36889
DVL3 dishevelled segment polarity protein 3 2.36889
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.36889
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 2.36889
EPHB3 EPH receptor B3 2.36889
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.36889
EHHADH-AS1 EHHADH antisense RNA 1 2.36889
MAGEF1 melanoma antigen family F1 2.36889
KLHL24 kelch-like family member 24 2.36889
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.36889
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.36889
VWA5B2 von Willebrand factor A domain containing 5B2 2.36889
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.36889
ECE2 endothelin converting enzyme 2 2.36889
LINC00888 long intergenic non-protein coding RNA 888 2.35236
SNORD66 small nucleolar RNA, C/D box 66 2.35236
KLHL6 kelch-like family member 6 2.35236
C3ORF70 chromosome 3 open reading frame 70 2.35236
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 2.3178
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.3178
LAMP3 lysosomal-associated membrane protein 3 2.30944
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.30944
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.30944
ATP11B ATPase, class VI, type 11B 2.283
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 2.283
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.26395
ACTL6A actin-like 6A 2.26395
MRPL47 mitochondrial ribosomal protein L47 2.26395
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 2.26395
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 2.25904
PEX5L peroxisomal biogenesis factor 5-like 2.25904
MFN1 mitofusin 1 2.25904
ZNF639 zinc finger protein 639 2.25904
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 2.25904
FXR1 fragile X mental retardation, autosomal homolog 1 2.24845
FLJ46066 uncharacterized LOC401103 2.24845
CCDC39 coiled-coil domain containing 39 2.24845
TTC14 tetratricopeptide repeat domain 14 2.24845
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 2.24845
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.24139
LOC100507634 uncharacterized LOC100507634 2.14116
BSND barttin CLCNK-type chloride channel accessory beta subunit 2.12703
ACOT11 acyl-CoA thioesterase 11 2.12703
FAM151A family with sequence similarity 151, member A 2.12703
USP24 ubiquitin specific peptidase 24 2.12703
TMEM61 transmembrane protein 61 2.12703
TTC4 tetratricopeptide repeat domain 4 2.12703
MROH7 maestro heat-like repeat family member 7 2.12703
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 2.12225
PCSK9 proprotein convertase subtilisin/kexin type 9 2.12225
TTC22 tetratricopeptide repeat domain 22 2.12225
C1ORF177 chromosome 1 open reading frame 177 2.12225
DHCR24 24-dehydrocholesterol reductase 2.12225
MIR938 microRNA 938 2.10177
MIR604 microRNA 604 2.10177
KDM4C lysine (K)-specific demethylase 4C 2.09628
SVIL supervillin 2.09529
GLDC glycine dehydrogenase (decarboxylating) 2.09117
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene 2.09117
LPIN2 lipin 2 2.09117
DLGAP1-AS5 DLGAP1 antisense RNA 5 2.09073
EMILIN2 elastin microfibril interfacer 2 2.09073
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 2.08781
TPD52L3 tumor protein D52-like 3 2.08781
IL33 interleukin 33 2.08781
KNG1 kininogen 1 2.08712
MYOM1 myomesin 1 2.08712
BCL6 B-cell CLL/lymphoma 6 2.08334
LOC100131635 hCG1645011-like 2.08334
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.08334
RTP2 receptor (chemosensory) transporter protein 2 2.08334
SST somatostatin 2.08334
RANBP6 RAN binding protein 6 2.08066
MIR4665 microRNA 4665 2.08066
MLANA melan-A 2.07822
KIAA2026 KIAA2026 2.07822
ERMP1 endoplasmic reticulum metallopeptidase 1 2.07822
LPP-AS2 LPP antisense RNA 2 2.07558
FLJ42393 uncharacterized LOC401105 2.07558
LPP LIM domain containing preferred translocation partner in lipoma 2.07346
SNORA63 small nucleolar RNA, H/ACA box 63 2.07338
SOX2 SRY (sex determining region Y)-box 2 2.06316
SOX2-OT SOX2 overlapping transcript 2.06316

low copy number

Symbol Name Standardized Value
DMXL1 Dmx-like 1 -3.7119
MAP7 microtubule-associated protein 7 -3.29865
ZFHX3 zinc finger homeobox 3 -3.15179
LOC390705 protein phosphatase 2, regulatory subunit B'', beta pseudogene -3.14331
TP53TG3B TP53 target 3B -3.14331
RNU6-76P RNA, U6 small nuclear 76, pseudogene -3.11641
IGH immunoglobulin heavy locus -3.07287