Keratinization Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
Description The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. (Gene Ontology, GO_0031424)
External Link https://reactome.org/PathwayBrowser/#/R-HSA-6805567
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Genes

217 proteins participating in the Keratinization pathway from the Reactome Pathways 2024 dataset.

Symbol Name
CAPN1 calpain 1, (mu/I) large subunit
CAPNS1 calpain, small subunit 1
CASP14 caspase 14, apoptosis-related cysteine peptidase
CDSN corneodesmosin
CELA2A chymotrypsin-like elastase family, member 2A
CSTA cystatin A (stefin A)
DSC1 desmocollin 1
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG2 desmoglein 2
DSG3 desmoglein 3
DSG4 desmoglein 4
DSP desmoplakin
EVPL envoplakin
FLG filaggrin
FURIN furin (paired basic amino acid cleaving enzyme)
IVL involucrin
JUP junction plakoglobin
KAZN kazrin, periplakin interacting protein
KLK12 kallikrein-related peptidase 12
KLK13 kallikrein-related peptidase 13
KLK14 kallikrein-related peptidase 14
KLK5 kallikrein-related peptidase 5
KLK8 kallikrein-related peptidase 8
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT12 keratin 12, type I
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT2 keratin 2, type II
KRT20 keratin 20, type I
KRT23 keratin 23, type I
KRT24 keratin 24, type I
KRT25 keratin 25, type I
KRT26 keratin 26, type I
KRT27 keratin 27, type I
KRT28 keratin 28, type I
KRT3 keratin 3, type II
KRT31 keratin 31, type I
KRT32 keratin 32, type I
KRT33A keratin 33A, type I
KRT33B keratin 33B, type I
KRT34 keratin 34, type I
KRT35 keratin 35, type I
KRT36 keratin 36, type I
KRT37 keratin 37, type I
KRT38 keratin 38, type I
KRT39 keratin 39, type I
KRT4 keratin 4, type II
KRT40 keratin 40, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRT7 keratin 7, type II
KRT71 keratin 71, type II
KRT72 keratin 72, type II
KRT73 keratin 73, type II
KRT74 keratin 74, type II
KRT75 keratin 75, type II
KRT76 keratin 76, type II
KRT77 keratin 77, type II
KRT78 keratin 78, type II
KRT79 keratin 79, type II
KRT8 keratin 8, type II
KRT80 keratin 80, type II
KRT81 keratin 81, type II
KRT82 keratin 82, type II
KRT83 keratin 83, type II
KRT84 keratin 84, type II
KRT85 keratin 85, type II
KRT86 keratin 86, type II
KRT9 keratin 9, type I
KRTAP1-1 keratin associated protein 1-1
KRTAP1-3 keratin associated protein 1-3
KRTAP1-4 keratin associated protein 1-4
KRTAP1-5 keratin associated protein 1-5
KRTAP10-1 keratin associated protein 10-1
KRTAP10-10 keratin associated protein 10-10
KRTAP10-11 keratin associated protein 10-11
KRTAP10-12 keratin associated protein 10-12
KRTAP10-2 keratin associated protein 10-2
KRTAP10-3 keratin associated protein 10-3
KRTAP10-4 keratin associated protein 10-4
KRTAP10-5 keratin associated protein 10-5
KRTAP10-6 keratin associated protein 10-6
KRTAP10-7 keratin associated protein 10-7
KRTAP10-8 keratin associated protein 10-8
KRTAP10-9 keratin associated protein 10-9
KRTAP11-1 keratin associated protein 11-1
KRTAP12-1 keratin associated protein 12-1
KRTAP12-2 keratin associated protein 12-2
KRTAP12-3 keratin associated protein 12-3
KRTAP12-4 keratin associated protein 12-4
KRTAP13-1 keratin associated protein 13-1
KRTAP13-2 keratin associated protein 13-2
KRTAP13-3 keratin associated protein 13-3
KRTAP13-4 keratin associated protein 13-4
KRTAP15-1 keratin associated protein 15-1
KRTAP16-1 keratin associated protein 16-1
KRTAP17-1 keratin associated protein 17-1
KRTAP19-1 keratin associated protein 19-1
KRTAP19-2 keratin associated protein 19-2
KRTAP19-3 keratin associated protein 19-3
KRTAP19-4 keratin associated protein 19-4
KRTAP19-5 keratin associated protein 19-5
KRTAP19-6 keratin associated protein 19-6
KRTAP19-7 keratin associated protein 19-7
KRTAP19-8 keratin associated protein 19-8
KRTAP2-1 keratin associated protein 2-1
KRTAP2-2 keratin associated protein 2-2
KRTAP2-3 keratin associated protein 2-3
KRTAP2-4 keratin associated protein 2-4
KRTAP20-1 keratin associated protein 20-1
KRTAP20-2 keratin associated protein 20-2
KRTAP21-1 keratin associated protein 21-1
KRTAP21-2 keratin associated protein 21-2
KRTAP21-3 keratin associated protein 21-3
KRTAP22-1 keratin associated protein 22-1
KRTAP23-1 keratin associated protein 23-1
KRTAP24-1 keratin associated protein 24-1
KRTAP25-1 keratin associated protein 25-1
KRTAP26-1 keratin associated protein 26-1
KRTAP27-1 keratin associated protein 27-1
KRTAP29-1 keratin associated protein 29-1
KRTAP3-1 keratin associated protein 3-1
KRTAP3-2 keratin associated protein 3-2
KRTAP3-3 keratin associated protein 3-3
KRTAP4-1 keratin associated protein 4-1
KRTAP4-11 keratin associated protein 4-11
KRTAP4-2 keratin associated protein 4-2
KRTAP4-3 keratin associated protein 4-3
KRTAP4-4 keratin associated protein 4-4
KRTAP4-5 keratin associated protein 4-5
KRTAP4-6 keratin associated protein 4-6
KRTAP4-7 keratin associated protein 4-7
KRTAP4-8 keratin associated protein 4-8
KRTAP4-9 keratin associated protein 4-9
KRTAP5-1 keratin associated protein 5-1
KRTAP5-10 keratin associated protein 5-10
KRTAP5-11 keratin associated protein 5-11
KRTAP5-2 keratin associated protein 5-2
KRTAP5-3 keratin associated protein 5-3
KRTAP5-4 keratin associated protein 5-4
KRTAP5-5 keratin associated protein 5-5
KRTAP5-6 keratin associated protein 5-6
KRTAP5-7 keratin associated protein 5-7
KRTAP5-8 keratin associated protein 5-8
KRTAP5-9 keratin associated protein 5-9
KRTAP6-1 keratin associated protein 6-1
KRTAP6-2 keratin associated protein 6-2
KRTAP6-3 keratin associated protein 6-3
KRTAP8-1 keratin associated protein 8-1
KRTAP9-1 keratin associated protein 9-1
KRTAP9-2 keratin associated protein 9-2
KRTAP9-3 keratin associated protein 9-3
KRTAP9-4 keratin associated protein 9-4
KRTAP9-6 keratin associated protein 9-6
KRTAP9-7 keratin associated protein 9-7
KRTAP9-8 keratin associated protein 9-8
KRTAP9-9 keratin associated protein 9-9
LCE1A late cornified envelope 1A
LCE1B late cornified envelope 1B
LCE1C late cornified envelope 1C
LCE1D late cornified envelope 1D
LCE1E late cornified envelope 1E
LCE1F late cornified envelope 1F
LCE2A late cornified envelope 2A
LCE2B late cornified envelope 2B
LCE2C late cornified envelope 2C
LCE2D late cornified envelope 2D
LCE3A late cornified envelope 3A
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LCE3D late cornified envelope 3D
LCE3E late cornified envelope 3E
LCE4A late cornified envelope 4A
LCE5A late cornified envelope 5A
LCE6A late cornified envelope 6A
LELP1 late cornified envelope-like proline-rich 1
LIPJ lipase, family member J
LIPK lipase, family member K
LIPM lipase, family member M
LIPN lipase, family member N
LORICRIN loricrin cornified envelope precursor protein
PCSK6 proprotein convertase subtilisin/kexin type 6
PERP PERP, TP53 apoptosis effector
PI3 peptidase inhibitor 3, skin-derived
PKP1 plakophilin 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PKP4 plakophilin 4
PPL periplakin
PRSS8 protease, serine, 8
RPTN repetin
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK9 serine peptidase inhibitor, Kazal type 9
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2A small proline-rich protein 2A
SPRR2B small proline-rich protein 2B
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR2F small proline-rich protein 2F
SPRR2G small proline-rich protein 2G
SPRR3 small proline-rich protein 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TCHH trichohyalin
TGM1 transglutaminase 1
TGM5 transglutaminase 5