Keratitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

812 genes co-occuring with the disease Keratitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
GJB2 gap junction protein, beta 2, 26kDa 3.022
IL1B interleukin 1, beta 2.81
KRT12 keratin 12, type I 2.712
IL6 interleukin 6 2.708
CD4 CD4 molecule 2.656
FGF2 fibroblast growth factor 2 (basic) 2.656
TNF tumor necrosis factor 2.642
NGF nerve growth factor (beta polypeptide) 2.62
KRT3 keratin 3, type II 2.616
IFNG interferon, gamma 2.592
KERA keratocan 2.569
MMP9 matrix metallopeptidase 9 2.563
GJB6 gap junction protein, beta 6, 30kDa 2.546
IL1A interleukin 1, alpha 2.495
LTF lactotransferrin 2.463
IL17A interleukin 17A 2.461
IL10 interleukin 10 2.458
TGFB1 transforming growth factor, beta 1 2.418
CXCL8 chemokine (C-X-C motif) ligand 8 2.418
TLR2 toll-like receptor 2 2.412
PECAM1 platelet/endothelial cell adhesion molecule 1 2.407
CD8A CD8a molecule 2.406
TLR4 toll-like receptor 4 2.401
TAC1 tachykinin, precursor 1 2.371
VEGFC vascular endothelial growth factor C 2.33
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.326
ALB albumin 2.317
CLEC7A C-type lectin domain family 7, member A 2.316
JDP2 Jun dimerization protein 2 2.309
PAX6 paired box 6 2.296
FLT1 fms-related tyrosine kinase 1 2.288
KDR kinase insert domain receptor 2.282
FN1 fibronectin 1 2.277
IL4 interleukin 4 2.277
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.275
CAMP cathelicidin antimicrobial peptide 2.272
CCL2 chemokine (C-C motif) ligand 2 2.27
FLT4 fms-related tyrosine kinase 4 2.269
MPO myeloperoxidase 2.249
FGF7 fibroblast growth factor 7 2.236
EGF epidermal growth factor 2.235
LACRT lacritin 2.233
COL18A1 collagen, type XVIII, alpha 1 2.212
IL2 interleukin 2 2.211
NECTIN1 nectin cell adhesion molecule 1 2.205
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 2.198
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.176
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.175
PTPRC protein tyrosine phosphatase, receptor type, C 2.167
GJB4 gap junction protein, beta 4, 30.3kDa 2.164
ICAM1 intercellular adhesion molecule 1 2.164
GJB3 gap junction protein, beta 3, 31kDa 2.152
MYD88 myeloid differentiation primary response 88 2.147
GYPC glycophorin C (Gerbich blood group) 2.133
THBS1 thrombospondin 1 2.127
IFNA1 interferon, alpha 1 2.126
MMP2 matrix metallopeptidase 2 2.115
VEGFD vascular endothelial growth factor D 2.108
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.105
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.098
PLG plasminogen 2.095
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.088
TLR3 toll-like receptor 3 2.079
DEFB4A defensin, beta 4A 2.076
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.071
CXCL10 chemokine (C-X-C motif) ligand 10 2.061
GJA1 gap junction protein, alpha 1, 43kDa 2.059
TLR5 toll-like receptor 5 2.057
IFNB1 interferon, beta 1, fibroblast 2.047
IL13 interleukin 13 2.039
LCN1 lipocalin 1 2.038
FGF10 fibroblast growth factor 10 2.038
TLR9 toll-like receptor 9 2.034
FGF16 fibroblast growth factor 16 2.034
FGF6 fibroblast growth factor 6 2.03
FGF22 fibroblast growth factor 22 2.025
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 2.019
FGF20 fibroblast growth factor 20 2.019
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.019
FGF9 fibroblast growth factor 9 2.018
FGF17 fibroblast growth factor 17 2.017
FGF5 fibroblast growth factor 5 2.016
IL18 interleukin 18 2.016
FGF18 fibroblast growth factor 18 2.015
FGF4 fibroblast growth factor 4 2.014
DCN decorin 2.012
FGF3 fibroblast growth factor 3 2.012
CCL3 chemokine (C-C motif) ligand 3 2.007
FGF8 fibroblast growth factor 8 (androgen-induced) 2.006
DEFB103A defensin, beta 103A 1.994
ACTB actin, beta 1.982
RTN4IP1 reticulon 4 interacting protein 1 1.981
LUM lumican 1.968
VEGFB vascular endothelial growth factor B 1.966
TAT tyrosine aminotransferase 1.959
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.956
TMSB4X thymosin beta 4, X-linked 1.949
PXDN peroxidasin 1.948
INS insulin 1.947
PXDNL peroxidasin-like 1.945
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.942
IL5 interleukin 5 1.94
GJA8 gap junction protein, alpha 8, 50kDa 1.921
PRTN3 proteinase 3 1.914
CLEC6A C-type lectin domain family 6, member A 1.913
CCL5 chemokine (C-C motif) ligand 5 1.911
IFNA2 interferon, alpha 2 1.911
IL1R1 interleukin 1 receptor, type I 1.906
GJB5 gap junction protein, beta 5, 31.1kDa 1.906
CRP C-reactive protein, pentraxin-related 1.889
GJB1 gap junction protein, beta 1, 32kDa 1.883
TJP1 tight junction protein 1 1.881
NLRP3 NLR family, pyrin domain containing 3 1.878
MMP3 matrix metallopeptidase 3 1.874
TIMP1 TIMP metallopeptidase inhibitor 1 1.873
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.872
MMP8 matrix metallopeptidase 8 1.872
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.872
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.87
DEFB1 defensin, beta 1 1.867
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.866
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.864
IRF3 interferon regulatory factor 3 1.863
AIRE autoimmune regulator 1.862
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.862
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.844
PGF placental growth factor 1.844
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.842
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.839
FGF13 fibroblast growth factor 13 1.838
CXCL2 chemokine (C-X-C motif) ligand 2 1.833
VIP vasoactive intestinal peptide 1.832
FASLG Fas ligand (TNF superfamily, member 6) 1.832
FOXP3 forkhead box P3 1.831
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.824
CD44 CD44 molecule (Indian blood group) 1.821
IL22 interleukin 22 1.819
CNTF ciliary neurotrophic factor 1.815
MMP1 matrix metallopeptidase 1 1.813
GJA3 gap junction protein, alpha 3, 46kDa 1.813
JUN jun proto-oncogene 1.81
CD86 CD86 molecule 1.809
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.803
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.799
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.793
RNASE7 ribonuclease, RNase A family, 7 1.792
TGFB2 transforming growth factor, beta 2 1.792
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 1.79
GSDMD gasdermin D 1.787
IGF1 insulin-like growth factor 1 (somatomedin C) 1.784
CD80 CD80 molecule 1.777
CARD9 caspase recruitment domain family, member 9 1.767
ELANE elastase, neutrophil expressed 1.762
C3 complement component 3 1.754
BDNF brain-derived neurotrophic factor 1.751
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.743
TGFBI transforming growth factor, beta-induced, 68kDa 1.732
ANGPT1 angiopoietin 1 1.73
TACR1 tachykinin receptor 1 1.729
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.727
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.727
VCAM1 vascular cell adhesion molecule 1 1.725
HMGB1 high mobility group box 1 1.721
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.721
KRT15 keratin 15, type I 1.717
CXCL9 chemokine (C-X-C motif) ligand 9 1.716
FAM20C family with sequence similarity 20, member C 1.716
LY96 lymphocyte antigen 96 1.71
CXCR2 chemokine (C-X-C motif) receptor 2 1.71
STAT1 signal transducer and activator of transcription 1, 91kDa 1.71
TK2 thymidine kinase 2, mitochondrial 1.707
CCL4 chemokine (C-C motif) ligand 4 1.706
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.705
CXCR4 chemokine (C-X-C motif) receptor 4 1.705
PILRA paired immunoglobin-like type 2 receptor alpha 1.699
IL17RA interleukin 17 receptor A 1.697
EGFR epidermal growth factor receptor 1.693
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.692
MAPK3 mitogen-activated protein kinase 3 1.687
TEK TEK tyrosine kinase, endothelial 1.686
THBS2 thrombospondin 2 1.684
HMOX1 heme oxygenase 1 1.681
DEFB4B defensin, beta 4B 1.679
CD34 CD34 molecule 1.678
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.676
TIMP2 TIMP metallopeptidase inhibitor 2 1.672
CCR2 chemokine (C-C motif) receptor 2 1.67
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.669
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.668
CD40 CD40 molecule, TNF receptor superfamily member 5 1.665
NLRC4 NLR family, CARD domain containing 4 1.66
CD68 CD68 molecule 1.656
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.655
GJC1 gap junction protein, gamma 1, 45kDa 1.654
IL17F interleukin 17F 1.651
CXCL12 chemokine (C-X-C motif) ligand 12 1.65
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.643
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.642
PRR4 proline rich 4 (lacrimal) 1.641
LGALS3 lectin, galactoside-binding, soluble, 3 1.641
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.638
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.636
CXCR3 chemokine (C-X-C motif) receptor 3 1.636
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.635
IFI16 interferon, gamma-inducible protein 16 1.631
CCL20 chemokine (C-C motif) ligand 20 1.63
TLR7 toll-like receptor 7 1.628
KRT14 keratin 14, type I 1.627
CSF3 colony stimulating factor 3 (granulocyte) 1.627
CD274 CD274 molecule 1.624
FOXC1 forkhead box C1 1.624
KRT4 keratin 4, type II 1.619
CLEC4E C-type lectin domain family 4, member E 1.616
ELN elastin 1.613
TLR1 toll-like receptor 1 1.611
ACE angiotensin I converting enzyme 1.61
CCK cholecystokinin 1.61
ERVW-1 endogenous retrovirus group W, member 1 1.602
TP53 tumor protein p53 1.602
BCL2 B-cell CLL/lymphoma 2 1.6
PTX3 pentraxin 3, long 1.596
NGFR nerve growth factor receptor 1.596
IL33 interleukin 33 1.594
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.592
RBP3 retinol binding protein 3, interstitial 1.587
HCFC1 host cell factor C1 1.587
MMP13 matrix metallopeptidase 13 1.583
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.579
CD36 CD36 molecule (thrombospondin receptor) 1.579
TBK1 TANK-binding kinase 1 1.577
SCARB2 scavenger receptor class B, member 2 1.574
IL17RC interleukin 17 receptor C 1.573
SCARB1 scavenger receptor class B, member 1 1.573
HSPG2 heparan sulfate proteoglycan 2 1.572
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.571
RHO rhodopsin 1.567
CGAS cyclic GMP-AMP synthase 1.565
CDH5 cadherin 5, type 2 (vascular endothelium) 1.564
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.563
GJA4 gap junction protein, alpha 4, 37kDa 1.563
THY1 Thy-1 cell surface antigen 1.562
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.562
SYK spleen tyrosine kinase 1.561
CALML5 calmodulin-like 5 1.558
ERV3-1 endogenous retrovirus group 3, member 1 1.557
COL8A2 collagen, type VIII, alpha 2 1.557
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.556
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.556
TSLP thymic stromal lymphopoietin 1.555
IL1RN interleukin 1 receptor antagonist 1.549
ANGPT2 angiopoietin 2 1.545
CYBB cytochrome b-245, beta polypeptide 1.544
HTN3 histatin 3 1.543
CALML3 calmodulin-like 3 1.542
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.542
CCN2 cellular communication network factor 2 1.541
SELE selectin E 1.541
GPX2 glutathione peroxidase 2 1.54
CALML6 calmodulin-like 6 1.54
CALML4 calmodulin-like 4 1.54
GDNF glial cell derived neurotrophic factor 1.537
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.532
LOX lysyl oxidase 1.531
AP1B1 adaptor-related protein complex 1, beta 1 subunit 1.529
CCL11 chemokine (C-C motif) ligand 11 1.526
CXCL5 chemokine (C-X-C motif) ligand 5 1.525
CD28 CD28 molecule 1.525
HLA-A major histocompatibility complex, class I, A 1.521
IFNA17 interferon, alpha 17 1.521
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.52
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 1.52
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.517
GDI1 GDP dissociation inhibitor 1 1.517
MUC16 mucin 16, cell surface associated 1.516
MMP10 matrix metallopeptidase 10 1.515
ACE2 angiotensin I converting enzyme 2 1.513
OCLN occludin 1.507
RPE65 retinal pigment epithelium-specific protein 65kDa 1.505
DEFB104A defensin, beta 104A 1.504
S100A12 S100 calcium binding protein A12 1.502
HPSE heparanase 1.502
NTF4 neurotrophin 4 1.501
GJA5 gap junction protein, alpha 5, 40kDa 1.5
MUC4 mucin 4, cell surface associated 1.499
PRF1 perforin 1 (pore forming protein) 1.497
KRT1 keratin 1, type II 1.495
FPR2 formyl peptide receptor 2 1.495
DEFB104B defensin, beta 104B 1.494
POMC proopiomelanocortin 1.493
PPARG peroxisome proliferator-activated receptor gamma 1.492
MMP7 matrix metallopeptidase 7 1.49
BECN1 beclin 1, autophagy related 1.489
KRT10 keratin 10, type I 1.489
TGM1 transglutaminase 1 1.487
SFTPD surfactant protein D 1.487
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.485
VTN vitronectin 1.484
IFNA4 interferon, alpha 4 1.483
KRT13 keratin 13, type I 1.48
TGFB3 transforming growth factor, beta 3 1.478
NTF3 neurotrophin 3 1.477
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.475
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.474
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.473
COL4A2 collagen, type IV, alpha 2 1.472
NECTIN2 nectin cell adhesion molecule 2 1.472
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.469
TLR8 toll-like receptor 8 1.467
GPX3 glutathione peroxidase 3 1.467
IRF7 interferon regulatory factor 7 1.466
IFNA10 interferon, alpha 10 1.465
KLK5 kallikrein-related peptidase 5 1.463
IFNA13 interferon, alpha 13 1.462
GPX6 glutathione peroxidase 6 1.462
PDGFB platelet-derived growth factor beta polypeptide 1.461
GPX5 glutathione peroxidase 5 1.461
GPX8 glutathione peroxidase 8 (putative) 1.46
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 1.46
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.46
IFNA6 interferon, alpha 6 1.459
GPX7 glutathione peroxidase 7 1.457
IFNA7 interferon, alpha 7 1.456
IFNA16 interferon, alpha 16 1.456
IFNA8 interferon, alpha 8 1.455
MAPK8 mitogen-activated protein kinase 8 1.454
IFNA5 interferon, alpha 5 1.454
CD46 CD46 molecule, complement regulatory protein 1.451
IFNA14 interferon, alpha 14 1.451
IFNA21 interferon, alpha 21 1.451
ANXA5 annexin A5 1.449
NTN4 netrin 4 1.446
AZU1 azurocidin 1 1.444
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.443
MMP12 matrix metallopeptidase 12 1.441
PGLYRP4 peptidoglycan recognition protein 4 1.441
CST4 cystatin S 1.44
IL7 interleukin 7 1.438
UNC5B unc-5 homolog B (C. elegans) 1.438
SDC1 syndecan 1 1.437
BGN biglycan 1.436
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 1.434
PITX2 paired-like homeodomain 2 1.434
LTA lymphotoxin alpha 1.433
NOD2 nucleotide-binding oligomerization domain containing 2 1.431
PGLYRP3 peptidoglycan recognition protein 3 1.431
IL15 interleukin 15 1.43
NID1 nidogen 1 1.425
GJC3 gap junction protein, gamma 3, 30.2kDa 1.423
MRC1 mannose receptor, C type 1 1.423
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.422
CYCS cytochrome c, somatic 1.421
TREM1 triggering receptor expressed on myeloid cells 1 1.419
MUC1 mucin 1, cell surface associated 1.416
GPR32 G protein-coupled receptor 32 1.414
ADGRB1 adhesion G protein-coupled receptor B1 1.413
IL36RN interleukin 36 receptor antagonist 1.413
UNC93B1 unc-93 homolog B1 (C. elegans) 1.411
TLR6 toll-like receptor 6 1.408
CD209 CD209 molecule 1.408
HSPA4 heat shock 70kDa protein 4 1.407
PROX1 prospero homeobox 1 1.406
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.404
S100A7 S100 calcium binding protein A7 1.404
CD19 CD19 molecule 1.4
ENG endoglin 1.396
ERBB2 erb-b2 receptor tyrosine kinase 2 1.396
AQP5 aquaporin 5 1.395
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.392
CCR1 chemokine (C-C motif) receptor 1 1.391
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.387
HBEGF heparin-binding EGF-like growth factor 1.386
NID2 nidogen 2 (osteonidogen) 1.385
FGF1 fibroblast growth factor 1 (acidic) 1.385
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.383
FLG filaggrin 1.383
SELL selectin L 1.38
CTSS cathepsin S 1.379
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.376
DOCK8 dedicator of cytokinesis 8 1.376
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 1.376
TRIM21 tripartite motif containing 21 1.372
IDO1 indoleamine 2,3-dioxygenase 1 1.371
CD207 CD207 molecule, langerin 1.37
DNTT DNA nucleotidylexotransferase 1.37
RHOA ras homolog family member A 1.37
GJC2 gap junction protein, gamma 2, 47kDa 1.369
CD40LG CD40 ligand 1.368
IL9 interleukin 9 1.368
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.367
NT5E 5'-nucleotidase, ecto (CD73) 1.367
HLA-B major histocompatibility complex, class I, B 1.366
CCR7 chemokine (C-C motif) receptor 7 1.366
NOD1 nucleotide-binding oligomerization domain containing 1 1.365
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.363
FLG2 filaggrin family member 2 1.355
CDC42 cell division cycle 42 1.354
VSX1 visual system homeobox 1 1.347
CTSF cathepsin F 1.346
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.344
AIM2 absent in melanoma 2 1.343
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.343
PLAU plasminogen activator, urokinase 1.342
JAK1 Janus kinase 1 1.341
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.337
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.336
IQCF3 IQ motif containing F3 1.335
PGLYRP1 peptidoglycan recognition protein 1 1.334
NIPAL4 NIPA-like domain containing 4 1.334
CCL17 chemokine (C-C motif) ligand 17 1.333
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.333
VASH1 vasohibin 1 1.332
CTAGE6 CTAGE family, member 6 1.332
CFH complement factor H 1.332
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 1.331
IRAK1 interleukin-1 receptor-associated kinase 1 1.331
ALOX15 arachidonate 15-lipoxygenase 1.329
KRT19 keratin 19, type I 1.328
NLRP12 NLR family, pyrin domain containing 12 1.327
IRF1 interferon regulatory factor 1 1.327
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.326
LAMP1 lysosomal-associated membrane protein 1 1.326
CTNS cystinosin, lysosomal cystine transporter 1.325
IL3 interleukin 3 1.325
TGFA transforming growth factor, alpha 1.324
IL4R interleukin 4 receptor 1.321
CXCL11 chemokine (C-X-C motif) ligand 11 1.32
BAX BCL2-associated X protein 1.318
PADI4 peptidyl arginine deiminase, type IV 1.318
CTSG cathepsin G 1.318
ISG15 ISG15 ubiquitin-like modifier 1.317
SLIT3 slit homolog 3 (Drosophila) 1.316
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.315
CTRB2 chymotrypsinogen B2 1.314
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.313
BMP4 bone morphogenetic protein 4 1.312
NOS2 nitric oxide synthase 2, inducible 1.312
PNPLA1 patatin-like phospholipase domain containing 1 1.31
CTRB1 chymotrypsinogen B1 1.308
PRDM12 PR domain containing 12 1.307
CRYGS crystallin, gamma S 1.306
IRS1 insulin receptor substrate 1 1.305
SIRT1 sirtuin 1 1.303
IFIH1 interferon induced with helicase C domain 1 1.301
NFE2L2 nuclear factor, erythroid 2-like 2 1.301
CTSB cathepsin B 1.298
GLB1 galactosidase, beta 1 1.297
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.296
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.296
LYZL1 lysozyme-like 1 1.294
NRP1 neuropilin 1 1.294
CLEC4D C-type lectin domain family 4, member D 1.292
MET MET proto-oncogene, receptor tyrosine kinase 1.291
EEF2 eukaryotic translation elongation factor 2 1.29
AIF1 allograft inflammatory factor 1 1.289
S100A4 S100 calcium binding protein A4 1.289
SAG S-antigen; retina and pineal gland (arrestin) 1.286
BST2 bone marrow stromal cell antigen 2 1.285
CCR3 chemokine (C-C motif) receptor 3 1.284
C21ORF91 chromosome 21 open reading frame 91 1.284
FOS FBJ murine osteosarcoma viral oncogene homolog 1.283
H2BC21 H2B clustered histone 21 1.282
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.281
ARG1 arginase 1 1.279
PF4 platelet factor 4 1.276
FGFR2 fibroblast growth factor receptor 2 1.276
APOE apolipoprotein E 1.275
KNG1 kininogen 1 1.274
AOC3 amine oxidase, copper containing 3 1.274
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.273
SMAD2 SMAD family member 2 1.273
CD160 CD160 molecule 1.271
IL36R interleukin 36 receptor 1.271
GSK3B glycogen synthase kinase 3 beta 1.269
F3 coagulation factor III (thromboplastin, tissue factor) 1.264
TIMP3 TIMP metallopeptidase inhibitor 3 1.264
ANXA1 annexin A1 1.262
IL24 interleukin 24 1.262
SPINT2 serine peptidase inhibitor, Kunitz type, 2 1.258
TKT transketolase 1.256
GJD2 gap junction protein, delta 2, 36kDa 1.255
PDCD1 programmed cell death 1 1.253
KRT6A keratin 6A, type II 1.252
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.252
TKTL2 transketolase-like 2 1.25
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.249
BMP7 bone morphogenetic protein 7 1.248
LGALS9 lectin, galactoside-binding, soluble, 9 1.248
SLURP1 secreted LY6/PLAUR domain containing 1 1.248
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.241
ALOX12B arachidonate 12-lipoxygenase, 12R type 1.24
PPARA peroxisome proliferator-activated receptor alpha 1.239
DNAH8 dynein, axonemal, heavy chain 8 1.239
CD59 CD59 molecule, complement regulatory protein 1.237
ALOXE3 arachidonate lipoxygenase 3 1.237
ZNF469 zinc finger protein 469 1.237
JAK2 Janus kinase 2 1.237
SLIT2 slit homolog 2 (Drosophila) 1.233
SOCS1 suppressor of cytokine signaling 1 1.233
FAS Fas cell surface death receptor 1.233
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.231
S100A1 S100 calcium binding protein A1 1.231
NTN1 netrin 1 1.23
PDGFC platelet derived growth factor C 1.23
CLEC1A C-type lectin domain family 1, member A 1.229
BCL2L1 BCL2-like 1 1.228
TACSTD2 tumor-associated calcium signal transducer 2 1.228
CCL21 chemokine (C-C motif) ligand 21 1.226
MUC7 mucin 7, secreted 1.226
PDPN podoplanin 1.226
TKTL1 transketolase-like 1 1.226
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.224
CD69 CD69 molecule 1.224
VWF von Willebrand factor 1.223
CSF1R colony stimulating factor 1 receptor 1.221
TSHR thyroid stimulating hormone receptor 1.221
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.22
MYH9 myosin, heavy chain 9, non-muscle 1.219
HTN1 histatin 1 1.218
CCR6 chemokine (C-C motif) receptor 6 1.217
ATG5 autophagy related 5 1.217
CCRL2 chemokine (C-C motif) receptor-like 2 1.216
ENO1 enolase 1, (alpha) 1.216
SLPI secretory leukocyte peptidase inhibitor 1.214
ANGPTL7 angiopoietin-like 7 1.213
OGN osteoglycin 1.213
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) 1.213
CTSL cathepsin L 1.212
COL4A1 collagen, type IV, alpha 1 1.211
LGALS8 lectin, galactoside-binding, soluble, 8 1.211
NOS3 nitric oxide synthase 3 (endothelial cell) 1.21
CA6 carbonic anhydrase VI 1.209
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.206
TREM2 triggering receptor expressed on myeloid cells 2 1.206
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.205
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.205
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.203
SOD1 superoxide dismutase 1, soluble 1.202
CD276 CD276 molecule 1.201
LOXHD1 lipoxygenase homology domains 1 1.201
TXN thioredoxin 1.2
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.199
CD63 CD63 molecule 1.198
PTK2 protein tyrosine kinase 2 1.196
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.193
SOCS3 suppressor of cytokine signaling 3 1.192
H3-4 H3.4 histone, cluster member 1.192
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.192
H3C12 H3 clustered histone 12 1.191
RAG2 recombination activating gene 2 1.19
H3-3B H3.3 histone B 1.189
VLDLR very low density lipoprotein receptor 1.189
TYR tyrosinase 1.189
AZGP1 alpha-2-glycoprotein 1, zinc-binding 1.188
SOX2 SRY (sex determining region Y)-box 2 1.187
H3C13 H3 clustered histone 13 1.187
H3-5 H3.5 histone 1.187
FOXO1 forkhead box O1 1.186
FOXC2 forkhead box C2 1.186
LGALS9C lectin, galactoside-binding, soluble, 9C 1.184
SAMD7 sterile alpha motif domain containing 7 1.182
SMAD7 SMAD family member 7 1.18
CST1 cystatin SN 1.18
CSF1 colony stimulating factor 1 (macrophage) 1.178
SOD2 superoxide dismutase 2, mitochondrial 1.178
NLRP1 NLR family, pyrin domain containing 1 1.176
EMP2 epithelial membrane protein 2 1.175
IFNGR1 interferon gamma receptor 1 1.174
CD163 CD163 molecule 1.174
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.173
FMOD fibromodulin 1.171
PXN paxillin 1.171
AGER advanced glycosylation end product-specific receptor 1.17
IFNL1 interferon, lambda 1 1.17
MYO7A myosin VIIA 1.17
EGR1 early growth response 1 1.169
FGFR1 fibroblast growth factor receptor 1 1.169
MLKL mixed lineage kinase domain-like 1.167
DLL4 delta-like 4 (Drosophila) 1.167
NOX4 NADPH oxidase 4 1.164
XPA xeroderma pigmentosum, complementation group A 1.163
MOG myelin oligodendrocyte glycoprotein 1.162
CREB1 cAMP responsive element binding protein 1 1.161
CCND1 cyclin D1 1.161
IL23R interleukin 23 receptor 1.161
MAVS mitochondrial antiviral signaling protein 1.158
IFNW1 interferon, omega 1 1.158
ACOD1 aconitate decarboxylase 1 1.158
CEP290 centrosomal protein 290kDa 1.157
KLF4 Kruppel-like factor 4 (gut) 1.157
CD1D CD1d molecule 1.156
IL17C interleukin 17C 1.156
ALOX5 arachidonate 5-lipoxygenase 1.155
PIP prolactin-induced protein 1.154
LCN2 lipocalin 2 1.154
HLA-G major histocompatibility complex, class I, G 1.154
RAG1 recombination activating gene 1 1.153
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.152
HDAC9 histone deacetylase 9 1.152
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.151
CFP complement factor properdin 1.151
TTR transthyretin 1.151
NELFCD negative elongation factor complex member C/D 1.15
PUS3 pseudouridylate synthase 3 1.15
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 1.149
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.148
VIM vimentin 1.148
MSRA methionine sulfoxide reductase A 1.148
SPDEF SAM pointed domain containing ETS transcription factor 1.147
GSR glutathione reductase 1.147
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.146
IDO2 indoleamine 2,3-dioxygenase 2 1.146
IL1F10 interleukin 1 family, member 10 (theta) 1.144
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.144
OTUD5 OTU deubiquitinase 5 1.144
SP100 SP100 nuclear antigen 1.144
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.144
RLBP1 retinaldehyde binding protein 1 1.142
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.142
PCNA proliferating cell nuclear antigen 1.142
IFNL2 interferon, lambda 2 1.141
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.139
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.139
PRKCA protein kinase C, alpha 1.139
EFNB2 ephrin-B2 1.139
NOTCH1 notch 1 1.139
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.138
MYH14 myosin, heavy chain 14, non-muscle 1.134
TMPRSS2 transmembrane protease, serine 2 1.132
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 1.13
DSG1 desmoglein 1 1.13
FOXO3 forkhead box O3 1.129
COL17A1 collagen, type XVII, alpha 1 1.128
SMAD3 SMAD family member 3 1.128
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.128
LYZ lysozyme 1.128
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.126
NCAM1 neural cell adhesion molecule 1 1.126
TEF thyrotrophic embryonic factor 1.126
LGALS9B lectin, galactoside-binding, soluble, 9B 1.126
AQP1 aquaporin 1 (Colton blood group) 1.125
NRP2 neuropilin 2 1.125
ANG angiogenin, ribonuclease, RNase A family, 5 1.124
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 1.124
PTGFR prostaglandin F receptor (FP) 1.124
TRAF3 TNF receptor-associated factor 3 1.124
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.122
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.118
LRP6 low density lipoprotein receptor-related protein 6 1.118
MAG myelin associated glycoprotein 1.117
HAVCR2 hepatitis A virus cellular receptor 2 1.116
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.116
RIPK3 receptor-interacting serine-threonine kinase 3 1.116
NEO1 neogenin 1 1.114
EPO erythropoietin 1.114
RNASE3 ribonuclease, RNase A family, 3 1.114
SPINK5 serine peptidase inhibitor, Kazal type 5 1.113
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.113
NPY neuropeptide Y 1.112
TYROBP TYRO protein tyrosine kinase binding protein 1.112
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.111
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.111
TYK2 tyrosine kinase 2 1.111
TBX21 T-box 21 1.111
MAPK14 mitogen-activated protein kinase 14 1.109
VIPR1 vasoactive intestinal peptide receptor 1 1.109
CD81 CD81 molecule 1.108
IL7R interleukin 7 receptor 1.107
DICER1 dicer 1, ribonuclease type III 1.107
CERS3 ceramide synthase 3 1.105
MBD4 methyl-CpG binding domain protein 4 1.103
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.102
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.101
PIGR polymeric immunoglobulin receptor 1.101
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.098
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.098
TLR10 toll-like receptor 10 1.097
STAT5B signal transducer and activator of transcription 5B 1.095
CXCR1 chemokine (C-X-C motif) receptor 1 1.095
DST dystonin 1.093
CLDN7 claudin 7 1.092
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.092
ZEB1 zinc finger E-box binding homeobox 1 1.091
TRPV3 transient receptor potential cation channel, subfamily V, member 3 1.089
B2M beta-2-microglobulin 1.088
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1.087
PENK proenkephalin 1.086
NUCLEOLIN nucleolin multifunctional protein 1.085
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.082
GJE1 gap junction protein, epsilon 1, 23kDa 1.082
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.081
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.08
CHUK conserved helix-loop-helix ubiquitous kinase 1.076
RSAD2 radical S-adenosyl methionine domain containing 2 1.076
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.074
ADAM10 ADAM metallopeptidase domain 10 1.073
STAT2 signal transducer and activator of transcription 2, 113kDa 1.072
MALT1 MALT1 paracaspase 1.072
JAK3 Janus kinase 3 1.072
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.07
PBK PDZ binding kinase 1.07
HLA-C major histocompatibility complex, class I, C 1.07
FADD Fas (TNFRSF6)-associated via death domain 1.065
CHIA chitinase, acidic 1.064
S100A6 S100 calcium binding protein A6 1.063
ARX aristaless related homeobox 1.062
TUB tubby bipartite transcription factor 1.06
PTEN phosphatase and tensin homolog 1.06
CLDN1 claudin 1 1.059
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 1.058
IL1RAP interleukin 1 receptor accessory protein 1.058
WNT6 wingless-type MMTV integration site family, member 6 1.057
ITGA9 integrin, alpha 9 1.056
CAV1 caveolin 1, caveolae protein, 22kDa 1.055
IGF1R insulin-like growth factor 1 receptor 1.055
IL2RA interleukin 2 receptor, alpha 1.055
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.055
GPKOW G patch domain and KOW motifs 1.054
NRTN neurturin 1.054
CLU clusterin 1.054
CKM creatine kinase, muscle 1.053
AHR aryl hydrocarbon receptor 1.053
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 1.052
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.052
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.052
CRLF2 cytokine receptor-like factor 2 1.051
CST2 cystatin SA 1.05
DCD dermcidin 1.05
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.05
MEFV Mediterranean fever 1.05
C1S complement component 1, s subcomponent 1.048
UBIAD1 UbiA prenyltransferase domain containing 1 1.048
CD83 CD83 molecule 1.047
BCL10 B-cell CLL/lymphoma 10 1.046
LIFR leukemia inhibitory factor receptor alpha 1.045
NCF1 neutrophil cytosolic factor 1 1.045
DEFB105A defensin, beta 105A 1.044
DNASE1 deoxyribonuclease I 1.044
DSP desmoplakin 1.044
NQO1 NAD(P)H dehydrogenase, quinone 1 1.043
FURIN furin (paired basic amino acid cleaving enzyme) 1.042
DHFR2 dihydrofolate reductase 2 1.042
CD38 CD38 molecule 1.041
TRIM8 tripartite motif containing 8 1.041
CKB creatine kinase, brain 1.041
EDN1 endothelin 1 1.04
NECTIN4 nectin cell adhesion molecule 4 1.04
MSLN mesothelin 1.039
VSX2 visual system homeobox 2 1.039
F2 coagulation factor II (thrombin) 1.039
ALCAM activated leukocyte cell adhesion molecule 1.038
CFL1 cofilin 1 (non-muscle) 1.037
S100A8 S100 calcium binding protein A8 1.036
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 1.035
IL11 interleukin 11 1.034
RCVRN recoverin 1.033
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1.033
LGALS7 lectin, galactoside-binding, soluble, 7 1.033
LGALS7B lectin, galactoside-binding, soluble, 7B 1.033
PI3 peptidase inhibitor 3, skin-derived 1.033
FOXE3 forkhead box E3 1.033
GUK1 guanylate kinase 1 1.032
PRG4 proteoglycan 4 1.032
CRYAA crystallin, alpha A 1.031
TUBB3 tubulin, beta 3 class III 1.029
BSG basigin (Ok blood group) 1.029
IFNLR1 interferon, lambda receptor 1 1.028
LCK LCK proto-oncogene, Src family tyrosine kinase 1.028
NLRP5 NLR family, pyrin domain containing 5 1.028
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.028
KRT5 keratin 5, type II 1.027
TCF15 transcription factor 15 (basic helix-loop-helix) 1.027
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.025
SST somatostatin 1.025
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.025
NUCB1 nucleobindin 1 1.025
DHFR dihydrofolate reductase 1.023
ERCC2 excision repair cross-complementation group 2 1.023
PLAUR plasminogen activator, urokinase receptor 1.022
CD47 CD47 molecule 1.022
GPHA2 glycoprotein hormone alpha 2 1.022
ATM ATM serine/threonine kinase 1.02
MPLKIP M-phase specific PLK1 interacting protein 1.019
A2M alpha-2-macroglobulin 1.018
CCL22 chemokine (C-C motif) ligand 22 1.018
CD27 CD27 molecule 1.018
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.016
HSH2D hematopoietic SH2 domain containing 1.015
METTL3 methyltransferase like 3 1.015
PPARD peroxisome proliferator-activated receptor delta 1.015
APP amyloid beta (A4) precursor protein 1.015
SPP1 secreted phosphoprotein 1 1.014
COL8A1 collagen, type VIII, alpha 1 1.014
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.013
CFL2 cofilin 2 (muscle) 1.013
CKMT1B creatine kinase, mitochondrial 1B 1.012
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.012
CST6 cystatin E/M 1.011
PANX1 pannexin 1 1.011
MATK megakaryocyte-associated tyrosine kinase 1.01
SPI1 Spi-1 proto-oncogene 1.01
NES nestin 1.009
CCL19 chemokine (C-C motif) ligand 19 1.009
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.009
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.006
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.005
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.004
ERCC3 excision repair cross-complementation group 3 1.004
IL37 interleukin 37 1.004
GPR18 G protein-coupled receptor 18 1.004
PTPRJ protein tyrosine phosphatase, receptor type, J 1.004
FZD4 frizzled class receptor 4 1.004
TJP2 tight junction protein 2 1.001