Keratitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0022568
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Genes

152 genes associated with the disease Keratitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIRE autoimmune regulator
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
APOE apolipoprotein E
AQP6 aquaporin 6, kidney specific
ARSA arylsulfatase A
ATF4 activating transcription factor 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL2 B-cell CLL/lymphoma 2
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CD38 CD38 molecule
CERS3 ceramide synthase 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRM3 cholinergic receptor, muscarinic 3
CLEC4E C-type lectin domain family 4, member E
CLEC7A C-type lectin domain family 7, member A
CNTF ciliary neurotrophic factor
COL7A1 collagen, type VII, alpha 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRLF1 cytokine receptor-like factor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DDB2 damage-specific DNA binding protein 2, 48kDa
DEFB1 defensin, beta 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2 fibroblast growth factor receptor 2
FLG filaggrin
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GRAP2 GRB2-related adaptor protein 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMGB1 high mobility group box 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL12B interleukin 12B
IL13RA2 interleukin 13 receptor, alpha 2
IL17A interleukin 17A
IL17RC interleukin 17 receptor C
IL1B interleukin 1, beta
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL24 interleukin 24
IL36RN interleukin 36 receptor antagonist
IL6 interleukin 6
IPP intracisternal A particle-promoted polypeptide
IRAK1 interleukin-1 receptor-associated kinase 1
ISG15 ISG15 ubiquitin-like modifier
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KIF22 kinesin family member 22
KRT14 keratin 14, type I
LTF lactotransferrin
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MBTPS2 membrane-bound transcription factor peptidase, site 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MMP12 matrix metallopeptidase 12
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NIPAL4 NIPA-like domain containing 4
NLRC3 NLR family, CARD domain containing 3
NLRC4 NLR family, CARD domain containing 4
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PANX1 pannexin 1
PAX6 paired box 6
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLB1 phospholipase B1
PLEC plectin
PNPLA1 patatin-like phospholipase domain containing 1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLH polymerase (DNA directed), eta
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PROX1 prospero homeobox 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT6 sirtuin 6
SMOX spermine oxidase
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SUMF2 sulfatase modifying factor 2
TAT tyrosine aminotransferase
TGFB1 transforming growth factor, beta 1
TGM1 transglutaminase 1
THBS1 thrombospondin 1
TIPE2 TNF alpha induced protein 8 like 2
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP63 tumor protein p63
TPT1 tumor protein, translationally-controlled 1
TREM1 triggering receptor expressed on myeloid cells 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIM8 tripartite motif containing 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSLP thymic stromal lymphopoietin
TSPO translocator protein (18kDa)
UBE3B ubiquitin protein ligase E3B
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIP vasoactive intestinal peptide
VWA3B von Willebrand factor A domain containing 3B
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB1 zinc finger E-box binding homeobox 1