Keratocystic Odontogenic Tumor Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A benign uni- or multicystic, intraosseous tumor of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium and potential for aggressive, infiltrative behaviour. (Human Phenotype Ontology, HP_0010603)
External Link https://www.disgenet.org/browser/0/1/0/C1708604
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Genes

54 genes associated with the disease Keratocystic Odontogenic Tumor in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
CALB2 calbindin 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CKAP4 cytoskeleton-associated protein 4
COX2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCTN6 dynactin 6
FGF8 fibroblast growth factor 8 (androgen-induced)
FHIT fragile histidine triad
FZD3 frizzled class receptor 3
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HPSE heparanase
HSPG2 heparan sulfate proteoglycan 2
IFI27 interferon, alpha-inducible protein 27
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
MAPK10 mitogen-activated protein kinase 10
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MTDH metadherin
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOTCH1 notch 1
NSG1 neuron specific gene family member 1
PCNA proliferating cell nuclear antigen
PDPN podoplanin
PI3 peptidase inhibitor 3, skin-derived
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTCH1 patched 1
PTCH2 patched 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RB1 retinoblastoma 1
RPE65 retinal pigment epithelium-specific protein 65kDa
RUNX2 runt-related transcription factor 2
SOX2 SRY (sex determining region Y)-box 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SUFU suppressor of fused homolog (Drosophila)
TCEAL1 transcription elongation factor A (SII)-like 1
TEAD4 TEA domain family member 4
TICAM2 toll-like receptor adaptor molecule 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TP53 tumor protein p53
TP63 tumor protein p63
UVRAG UV radiation resistance associated
WNT1 wingless-type MMTV integration site family, member 1