Kidney Calculi Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0022650
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Genes

175 genes associated with the disease Kidney Calculi in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACKR3 atypical chemokine receptor 3
ADI1 acireductone dioxygenase 1
ADRA1A adrenoceptor alpha 1A
ADRA2B adrenoceptor alpha 2B
AGXT alanine-glyoxylate aminotransferase
AHSG alpha-2-HS-glycoprotein
ALB albumin
ALPL alkaline phosphatase, liver/bone/kidney
ALPP alkaline phosphatase, placental
AMBP alpha-1-microglobulin/bikunin precursor
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
APRT adenine phosphoribosyltransferase
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ASRGL1 asparaginase like 1
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATRNL1 attractin-like 1
BEST1 bestrophin 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BRS3 bombesin-like receptor 3
CA2 carbonic anhydrase II
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALCR calcitonin receptor
CAPN1 calpain 1, (mu/I) large subunit
CARMIL1 capping protein regulator and myosin 1 linker 1
CASR calcium-sensing receptor
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CD14 CD14 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHD1 chromodomain helicase DNA binding protein 1
CLC Charcot-Leyden crystal galectin
CLCN5 chloride channel, voltage-sensitive 5
CLCN7 chloride channel, voltage-sensitive 7
CLDN14 claudin 14
CLDN16 claudin 16
CLDN19 claudin 19
CRYZ crystallin, zeta (quinone reductase)
CXCR6 chemokine (C-X-C motif) receptor 6
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DEFB1 defensin, beta 1
DGKD diacylglycerol kinase, delta 130kDa
DGKH diacylglycerol kinase, eta
DMD dystrophin
EDNRA endothelin receptor type A
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
ENO1 enolase 1, (alpha)
F2 coagulation factor II (thrombin)
FAM20A family with sequence similarity 20, member A
FGF23 fibroblast growth factor 23
FLNA filamin A, alpha
FN1 fibronectin 1
FOXO1 forkhead box O1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLI2 GLI family zinc finger 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR42 G protein-coupled receptor 42 (gene/pseudogene)
GPX1 glutathione peroxidase 1
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRPR gastrin-releasing peptide receptor
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIPK2 homeodomain interacting protein kinase 2
HMGB1 high mobility group box 1
HPGDS hematopoietic prostaglandin D synthase
HPR haptoglobin-related protein
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INSM1 insulinoma-associated 1
ITPKC inositol-trisphosphate 3-kinase C
KL klotho
KLK3 kallikrein-related peptidase 3
LAT2 linker for activation of T cells family, member 2
LCN2 lipocalin 2
LPAR2 lysophosphatidic acid receptor 2
LPO lactoperoxidase
LRP2 low density lipoprotein receptor-related protein 2
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MAPK8 mitogen-activated protein kinase 8
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MGP matrix Gla protein
MLXIP MLX interacting protein
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MTNR1A melatonin receptor 1A
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC4 mucin 4, cell surface associated
MYLIP myosin regulatory light chain interacting protein
NAT10 N-acetyltransferase 10 (GCN5-related)
NCF1 neutrophil cytosolic factor 1
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NRK Nik related kinase
ORAI1 ORAI calcium release-activated calcium modulator 1
PBX1 pre-B-cell leukemia homeobox 1
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDLIM3 PDZ and LIM domain 3
PFN3 profilin 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLIN5 perilipin 5
PODXL podocalyxin-like
POMC proopiomelanocortin
POU2AF1 POU class 2 associating factor 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRRT2 proline-rich transmembrane protein 2
PTH parathyroid hormone
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS14 regulator of G-protein signaling 14
SCN10A sodium channel, voltage gated, type X alpha subunit
SHROOM3 shroom family member 3
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLPI secretory leukocyte peptidase inhibitor
SOD1 superoxide dismutase 1, soluble
SPP1 secreted phosphoprotein 1
SSTR4 somatostatin receptor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UMOD uromodulin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
WDR72 WD repeat domain 72
XDH xanthine dehydrogenase
XPR1 xenotropic and polytropic retrovirus receptor 1